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Research Interests

My personal research interest in the areas of pre-eclampsia and haemostasis in pregnancy were formed as a research fellow at the Rotunda Hospital and at the Department of Obstetrics and Gynaecology, Trinity College, Dublin. This two year fellowship formed the basis of my MD thesis but also provided me with important exposure to the planning, organisation and management of a large clinical research projects and "hands on" laboratory work in the coagulation laboratory, TCD. This experience highlighted to me the importance of clinicians being exposed to the full range of research methodologies from epidemiology through to bench technologies. To further strengthen my own research training, as part of a perinatal medicine fellowship at the Royal Women's Hospital, Melbourne, I went "back to the bench", this time to learn a range of molecular research techniques. My personal research philosophy is that a clinical academic should act as an advocate for the clinical disorders and conditions of relevance to them. Through collaboration, the full repertoire of research methodologies should to be brought to bear on any specific clinical problem. My MD thesis and additional research work simultaneously undertaken on folic catabolism in pregnancy were funded by grants from the HRB and Welcome Trust respectively - grants which I wrote myself. At that time the vast majority of trainees in our specialty seeking to pursue research fellowship and an academic career would have pursued such research options overseas. Building research capacity in Ireland in Obstetrics and Gynaecology has been a long term ambition.

On returning to Ireland, to the Chair in Obstetrics and Gynaecology in U.C.C., the opportunity arose to develop a research centre dedicated to women's health and reproduction. Together with colleagues we have ensured that significant capital infrastructure in research has been developed in parallel with the construction of Cork University Maternity Hospital. The personal demands, of ensuring the successful amalgamation of three maternity hospitals and the development of the Anu Research Centre, interrupted my own research agenda. I have, however, maintained an ongoing interest in the area of haemostasis in pregnancy, including clinical issues relating to venous and arterial thrombosis in pregnancy and the application of therapeutic modalities. It is in the area of pregnancy haemostasis that I intend to continue to pursue a personal research agenda.

In addition, and perhaps more importantly, I wish to continue to contribute both in leadership and facilitator roles to the development of three separate levels of research endeavour within the U.C.C. Department of Obstetrics and Gynaecology.

Level 1: to strengthen the long tradition of clinical research among our specialist trainees. We want to ensure that this remains an essential component rather than an optional component of their training.

Level 2: the development of a strong range of MSc. projects and of MD/PhD research projects for trainees in the specialty in Obstetrics and Gynaecology.

Lever 3: the development of research programmes with PhD, post-doctorate opportunities etc. in the three major theme areas of the Anu Research Centre.

Research Grants

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Book Chapters

Peer Reviewed Journals

	Year	Publication
	(2014)	'Associations between health literacy and beliefs about medicines in an Irish obstetric population' Duggan L, McCarthy S, Curtis LM, Wolf MS, Noone C, Higgins JR, O'Shea S, Sahm LJ (2014) 'Associations between health literacy and beliefs about medicines in an Irish obstetric population'. Journal of Health Communication, 19 Suppl 2 :106-114 [DOI] [Details]
	(2014)	'Day Care Compared With Inpatient Management of Nausea and Vomiting of Pregnancy A Randomized Controlled Trial' McCarthy, FP,Murphy, A,Khashan, AS,McElroy, B,Spillane, N,Marchocki, Z,Sarkar, R,Higgins, JR (2014) 'Day Care Compared With Inpatient Management of Nausea and Vomiting of Pregnancy A Randomized Controlled Trial'. Obstetrics & Gynaecology, 124 :743-748 [DOI] [Details]
	(2014)	'Weight-adjusted LMWH prophylaxis provides more effective thrombin inhibition in morbidly obese pregnant women' Ismail SK, Norris L, O'Shea S, Higgins JR (2014) 'Weight-adjusted LMWH prophylaxis provides more effective thrombin inhibition in morbidly obese pregnant women'. Thrombosis Research, 134 (2):234-239 [DOI] [Details]
	(2014)	'Umbilical and fetal middle cerebral artery Doppler reference ranges in a twin population followed longitudinally from 24 to 38 weeks' gestation' Mulcahy, C,McAuliffe, FM,Breathnach, F,Geary, M,Daly, S,Higgins, J,Hunter, A,Morrison, J,Burke, G,Higgins, S,Dicker, P,Mahony, R,Tully, E,Malone, F (2014) 'Umbilical and fetal middle cerebral artery Doppler reference ranges in a twin population followed longitudinally from 24 to 38 weeks' gestation'. Ultrasound In Obstetrics & Gynecology, 44 :461-467 [DOI] [Details]
	(2014)	'Comparison of outcomes of twins conceived spontaneously and by artificial reproductive therapy' Anbazhagan, A,Hunter, A,Breathnach, FM,Mcauliffe, FM,Geary, MP,Daly, S,Higgins, JR,Morrison, JJ,Burke, G,Higgins, S,Dicker, P,Tully, E,Carroll, S,Malone, FD (2014) 'Comparison of outcomes of twins conceived spontaneously and by artificial reproductive therapy'. Journal Of Maternal-Fetal & Neonatal Medicine, 27 :458-462 [DOI] [Details]
	(2014)	'The influence of maternal body mass index on fetal weight estimation in twin pregnancy' Ryan, HM,Morrison, JJ,Breathnach, FM,McAuliffe, FM,Geary, MP,Daly, S,Higgins, JR,Hunter, A,Burke, G,Higgins, S,Mahony, R,Dicker, P,Manning, F,Tully, E,Malone, FD (2014) 'The influence of maternal body mass index on fetal weight estimation in twin pregnancy'. American Journal of Obstetrics and Gynaecology, 210 [DOI] [Details]
	(2013)	'Implementation of thromboprophylaxis guidelines' Cregan A, Higgins JR, O'Shea S (2013) 'Implementation of thromboprophylaxis guidelines'. Irish medical journal, 106 (3):80-82 [Details]
	(2013)	'Prediction of outcome in twin pregnancy with first and early second trimester ultrasound' O'Connor C, McAuliffe FM, Breathnach FM, Geary M, Daly S, Higgins JR, Dornan J, Morrison JJ, Burke G, Higgins S, Mooney E, Dicker P, Manning F, McParland P, Malone FD (2013) 'Prediction of outcome in twin pregnancy with first and early second trimester ultrasound'. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 26 (10):1030-1035 [DOI] [Details]
	(2012)	'Placental pathology, birthweight discordance, and growth restriction in twin pregnancy: results of the ESPRiT Study' Malone FD, Kent EM, Breathnach FM, Gillan JE, McAuliffe FM, Geary MP, Daly S, Higgins JR, Hunter A, Morrison JJ, Burke G, Higgins S, Carroll S, Dicker P, Manning F, Tully E (2012) 'Placental pathology, birthweight discordance, and growth restriction in twin pregnancy: results of the ESPRiT Study'. American Journal of Obstetrics and Gynaecology, 207 (3):2200-2205 [DOI] [Details]
	(2012)	'The PAI-1 4G/5G polymorphism is not associated with an increased risk of adverse pregnancy outcome in asymptomatic nulliparous women' Said JM, Tsui R, Borg AJ, Higgins JR, Moses EK, Walker SP, Monagle PT, Brennecke SP (2012) 'The PAI-1 4G/5G polymorphism is not associated with an increased risk of adverse pregnancy outcome in asymptomatic nulliparous women'. Journal of Thrombosis and Haemostasis, 10 (5):881-886 [DOI] [Details]
	(2012)	'Inherited thrombophilias and adverse pregnancy outcomes: a case-control study in an Australian population' Said, JM,Higgins, JR,Moses, EK,Walker, SP,Monagle, PT,Brennecke, SP (2012) 'Inherited thrombophilias and adverse pregnancy outcomes: a case-control study in an Australian population'. Acta Obstetricia Et Gynecologica Scandinavica, 91 :250-255 [DOI] [Details]
	(2012)	'Investigation of the role of multidetector computer tomography in the evaluation of stillbirth: a prospective study' K O’Donoghue, K O’Regan, CP Sheridan, OJ O’Connor, J Benson, R Chopra, Moore N, Murphy MJ, Higgins JR, Maher M. (2012) 'Investigation of the role of multidetector computer tomography in the evaluation of stillbirth: a prospective study'. European Journal of Radiology, [Details]
	(2012)	'Thrombin generation post elective caesarean section: Effect of low molecular weight heparin' Ismail, SK,Norris, L,Muttukrishna, S,Higgins, JR (2012) 'Thrombin generation post elective caesarean section: Effect of low molecular weight heparin'. Thrombosis Research, 130 :799-803 [DOI] [Details]
	(2012)	'Optimum Timing for Planned Delivery of Uncomplicated Monochorionic and Dichorionic Twin Pregnancies' Breathnach, FM,McAuliffe, FM,Geary, M,Daly, S,Higgins, JR,Dornan, J,Morrison, JJ,Burke, G,Higgins, S,Dicker, P,Manning, F,Carroll, S,Malone, FD (2012) 'Optimum Timing for Planned Delivery of Uncomplicated Monochorionic and Dichorionic Twin Pregnancies'. Obstetrics & Gynaecology, 119 :50-59 [DOI] [Details]
	(2011)	'Investigation of the role of computed tomography as an adjunct to autopsy in the evaluation of stillbirth' O'Donoghue K, O'Regan KN, Sheridan CP, O'Connor OJ, Benson J, McWilliams S, Moore N, Murphy MJ, Chopra R, Higgins JR, Maher MM.; (2011) 'Investigation of the role of computed tomography as an adjunct to autopsy in the evaluation of stillbirth'. European Journal of Radiology, [Details]
	(2011)	'Prediction of safe and successful vaginal twin birth' Breathnach FM, McAuliffe FM, Geary M, Daly S, Higgins JR, Dornan J, Morrison JJ, Burke G, Higgins S, Dicker P, Manning F, Carroll S, Malone FD (2011) 'Prediction of safe and successful vaginal twin birth'. American Journal of Obstetrics and Gynaecology, 205 (3):2370-2377 [DOI] [Details]
	(2011)	'Hemostasis in Pre-Eclampsia' Ismail, SK,Higgins, JR; (2011) 'Hemostasis in Pre-Eclampsia'. Seminars In Thrombosis and Hemostasis, 37 :111-117 [DOI] [Details]
	(2011)	'Definition of intertwin birth weight discordance' Breathnach FM, McAuliffe FM, Geary M, Daly S, Higgins JR, Dornan J, Morrison JJ, Burke G, Higgins S, Dicker P, Manning F, Mahony R, Malone FD (2011) 'Definition of intertwin birth weight discordance'. Obstetrics and Gynecology, 118 (1):94-103 [DOI] [Details]
	(2011)	'Inherited thrombophilias and adverse pregnancy outcomes: a case-control study in an Australian population' Said JM, Higgins JR, Moses EK, Walker SP, Monagle PT, Brennecke SP (2011) 'Inherited thrombophilias and adverse pregnancy outcomes: a case-control study in an Australian population'. Obstetrics and Gynecology, [DOI] [Details]
	(2011)	'Response of serum 25-hydroxyvitamin D concentrations to vitamin D supplementation during lactation' Zhang JY, Lucey AJ, Higgins JR, Cashman KD, Kiely M. (2011) 'Response of serum 25-hydroxyvitamin D concentrations to vitamin D supplementation during lactation'. Annals of Nutrition and Metabolism, 58 :179-180 [Details]
	(2011)	'Placental cord insertion and birthweight discordance in twin pregnancies: results of the national prospective ESPRiT Study' Kent EM, Breathnach FM, Gillan JE, McAuliffe FM, Geary MP, Daly S, Higgins JR, Dornan J, Morrison JJ, Burke G, Higgins S, Carroll S, Dicker P, Manning F, Malone FD (2011) 'Placental cord insertion and birthweight discordance in twin pregnancies: results of the national prospective ESPRiT Study'. American Journal of Obstetrics and Gynaecology, 205 (4):3760-3767 [DOI] [Details]
	(2010)	'The natural history of anencephaly' Obeidi N, Russell N, Higgins JR, O'Donoghue K; (2010) 'The natural history of anencephaly'. Prenatal Diagnosis, 30 (4):357-360 [DOI] [Details]
	(2010)	'The managment of reduced fetal movements at term:results of an anonymous national online survey in the Republic of Ireland' Unterscheider, J; Horgan, RP; Greene, RA; Higgins, JR (2010) 'The managment of reduced fetal movements at term:results of an anonymous national online survey in the Republic of Ireland'. Journal of Obstetrics and Gynaecology, [Details]
	(2010)	'Inherited Thrombophilia Polymorphisms and Pregnancy Outcomes in Nulliparous Women' Said, JM,Higgins, JR,Moses, EK,Walker, SP,Borg, AJ,Monagle, PT,Brennecke, SP; (2010) 'Inherited Thrombophilia Polymorphisms and Pregnancy Outcomes in Nulliparous Women'. Obstetrics and Gynecology, 115 :5-13 [Details]
	(2010)	'Altered reference ranges for protein C and protein S during early pregnancy: Implications for the diagnosis of protein C and protein S deficiency during pregnancy' Said, JM,Ignjatovic, V,Monagle, PT,Walker, SP,Higgins, JR,Brennecke, SP; (2010) 'Altered reference ranges for protein C and protein S during early pregnancy: Implications for the diagnosis of protein C and protein S deficiency during pregnancy'. Thrombosis and Haemostasis, 103 :984-988 [DOI] [Details]
	(2009)	'Expression of Pleiotrophin and its Receptors in Human Placenta Suggests Roles in Trophoblast Life Cycle and Angiogenesis' Ball, M,Carmody, M,Wynne, F,Dockery, P,Aigner, A,Cameron, I,Higgins, J,Smith, SD,Aplin, JD,Moore, T; (2009) 'Expression of Pleiotrophin and its Receptors in Human Placenta Suggests Roles in Trophoblast Life Cycle and Angiogenesis'. Placenta, 30 :649-653 [DOI] [Details]
	(2009)	'Fetal heart rate patterns in neonatal hypoxic-ischemic encephalopathy: relationship with early cerebral activity and neurodevelopmental outcome' Murray DM, O'Riordan MN, Horgan R, Boylan G, Higgins JR, Ryan CA; (2009) 'Fetal heart rate patterns in neonatal hypoxic-ischemic encephalopathy: relationship with early cerebral activity and neurodevelopmental outcome'. American Journal of Perinatology, 26 (8):605-612 [DOI] [Details]
	(2008)	'Self-collected versus health professional-collected genital swabs to identify the prevalence of group B streptococcus: a comparison of patient preference and efficacy' Arya, A., Cryan, B., O'Sullivan, K., Greene, R.A., Higgins, J.R. (2008) 'Self-collected versus health professional-collected genital swabs to identify the prevalence of group B streptococcus: a comparison of patient preference and efficacy'. European Journal of Obstetrics & Gynecology and Reproductive Biology, 139 (1):43-45 [DOI] [Details]
	(2008)	'The decline of laparoscopic sterilisation' Horgan R, Higgins JR, Burke G; (2008) 'The decline of laparoscopic sterilisation'. Irish Medical Journal, 101 (2):53-55 [CORA Link] [Details]
	(2008)	'The prevalence of inherited thrombophilic polymorphisms in an asymptomatic Australian antenatal population' Said, JM,Brennecke, SP,Moses, EK,Walker, SP,Monagle, PT,Campbell, J,Bryant, VJ,Borg, AJ,Higgins, JR (2008) 'The prevalence of inherited thrombophilic polymorphisms in an asymptomatic Australian antenatal population'. Australian & New Zealand Journal Of Obstetrics & Gynaecology, 48 :536-541 [DOI] [Details]
	(2008)	'Timing of birth related to obstetric practice and neonatal outcome' O'Donoghue K, Sheridan CP, O'Sullivan K, Greene RA, Higgins JR; (2008) 'Timing of birth related to obstetric practice and neonatal outcome'. Irish Medical Journal, 101 (7):205-207 [Details]
	(2008)	'Prevalence of suboptimal vitamin D status during pregnancy' O'Riordan MN, Kiely M, Higgins JR, Cashman KD. (2008) 'Prevalence of suboptimal vitamin D status during pregnancy'. Irish Medical Journal, 101 (8):1-3 [Details]
	(2007)	'Audit of antenatal clinic for high-risk obstetric patients; activity and outcomes' Allen C, Greene R, Higgins J; (2007) 'Audit of antenatal clinic for high-risk obstetric patients; activity and outcomes'. Irish Medical Journal, 100 (9):591-593 [Details]
	(2006)	'Poor uptake of reproductive health screening services by female renal transplant recipients' Kerkhoff BA, O'Connor TC, Plant WD, Higgins Jr; (2006) 'Poor uptake of reproductive health screening services by female renal transplant recipients'. Irish Medical Journal, 99 (3):78-80 [Details]
	(2006)	'Ethnic differences in the prevalence of inherited thrombophilic polymorphisms in an asymptomatic Australian prenatal population' Said JM; Brennecke SP; Moses EK; Walker SP; Borg AJ; Williams JT; Higgins JR; (2006) 'Ethnic differences in the prevalence of inherited thrombophilic polymorphisms in an asymptomatic Australian prenatal population'. Human biology; an international record of research, 78 (4):403-412 [DOI] [CORA Link] [Details]
	(2005)	'Ascertaining women's preferred mode of address and preferred choice of title during pregnancy and childbirth' Horgan R, Guha S, Sullivan KO, Higgins JR.; (2005) 'Ascertaining women's preferred mode of address and preferred choice of title during pregnancy and childbirth'. Irish Medical Journal, 98 (2):55-57 [Details]
	(2005)	'Management of valvular heart disease' Higgins JR; (2005) 'Management of valvular heart disease'. Thrombosis Research, 115 Suppl 1 :32-34 [Details]
	(2004)	'Patient satisfaction with the SpaceLabs 90207 ambulatory blood pressure monitor in pregnancy' Walker SP, Permezel MJ, Brennecke SP, Tuttle LK, Higgins JR; (2004) 'Patient satisfaction with the SpaceLabs 90207 ambulatory blood pressure monitor in pregnancy'. Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy, 23 (3):295-301 [DOI] [Details]
	(2003)	'Haemostasis in normal and abnormal pregnancy' O'Riordan MN, Higgins JR; (2003) 'Haemostasis in normal and abnormal pregnancy'. Best practice & research. Clinical obstetrics & gynaecology, 17 (3):385-396 [Details]
	(2002)	'Thrombomodulin Ala455Val dimorphism is not associated with pre-eclampsia in Australian and New Zealand women' Borg, AJ,Higgins, JR,Brennecke, SP,Moses, EK; (2002) 'Thrombomodulin Ala455Val dimorphism is not associated with pre-eclampsia in Australian and New Zealand women'. Gynecologic And Obstetric Investigation, 54 :43-45 [Details]
	(2002)	'The effect of hospitalisation on ambulatory blood pressure in pregnancy' Walker S, Permezel M, Brennecke S, Tuttle L, Ugoni A, Higgins J; (2002) 'The effect of hospitalisation on ambulatory blood pressure in pregnancy'. Journal of Obstetrics and Gynaecology, 42 (5):490-493 [Details]
	(2002)	'Ascertaining women's choice of title during pregnancy and childbirth' Denning AS, Tuttle LK, Bryant VJ, Walker SP, Higgins JR; (2002) 'Ascertaining women's choice of title during pregnancy and childbirth'. Journal of Obstetrics and Gynaecology, 42 (2):125-129 [Details]
	(2002)	'The effect of hospitalisation on ambulatory blood pressure in pregnancy' Walker, S,Permezel, M,Brennecke, S,Tuttle, L,Ugoni, A,Higgins, J; (2002) 'The effect of hospitalisation on ambulatory blood pressure in pregnancy'. Rna-A Publication of The Rna Society, 42 :490-493 [Details]
	(2002)	'The relationship between maternal work, ambulatory blood pressure, and pregnancy hypertension' Higgins J.R.; Walshe J.J.; Conroy R.M.; Darling M.R. (2002) 'The relationship between maternal work, ambulatory blood pressure, and pregnancy hypertension'. Journal of Epidemiology and Community Health, 56 (5):389-393 [DOI] [CORA Link] [Details]
	(2001)	'Maternal work significantly increases ambulatory blood pressure in late pregnancy' Walker S.P., Permezel M.P., Brennecke S.P., Ugoni A., Higgins, J.R.; (2001) 'Maternal work significantly increases ambulatory blood pressure in late pregnancy'. Obstetrics and Gynecology, Obstetrics & Gynaecology (97):361-365 [Details]
	(2001)	'Blood pressure in late pregnancy and work outside the home' Walker SP, Permezel M, Brennecke SP, Ugoni AM, Higgins JR; (2001) 'Blood pressure in late pregnancy and work outside the home'. Obstetrics and Gynecology, 97 (3):361-365 [Details]
	(2001)	'Anticoagulation in pregnancy and the puerperium' Hague WM, North RA, Gallus AS, Walters BN, Orlikowski C, Burrows RF, Cincotta RB, Dekker GA, Higgins JR, Lowe SA, Morris JM, Peek MJ; (2001) 'Anticoagulation in pregnancy and the puerperium'. The Medical Journal of Australia, 175 (5):258-263 [Details]
	(2001)	'Blood-pressure measurement and classification in pregnancy' Higgins JR, de Swiet M; (2001) 'Blood-pressure measurement and classification in pregnancy'. Lancet, 357 (9250):131-135 [DOI] [Details]
	(2000)	'Pregnancy and the impact of inherited thrombophilias' Higgins JR; (2000) 'Pregnancy and the impact of inherited thrombophilias'. Journal of Obstetrics and Gynaecology, 40 (2):118-121 [Details]
	(2000)	'The effect of pre-eclampsia on coagulation and fibrinolytic activation in the neonate' Higgins JR, Bonnar J, Norris LA, Darling MR, Walshe JJ; (2000) 'The effect of pre-eclampsia on coagulation and fibrinolytic activation in the neonate'. Thrombosis Research, 99 (6):567-570 [Details]
	(2000)	'Prothrombin G20210A mutation: is it associated with pre-eclampsia?' Higgins JR, Kaiser T, Moses EK, North R, Brennecke SP (2000) 'Prothrombin G20210A mutation: is it associated with pre-eclampsia?'. Gynecologic And Obstetric Investigation, 50 (4):361-365 [Details]
	(2000)	'Management of essential thrombocythaemia during pregnancy' Cincotta R, Higgins JR, Tippett C, Gallery E, North R, McMahon LP, Brennecke SP; (2000) 'Management of essential thrombocythaemia during pregnancy'. Journal of Obstetrics and Gynaecology, 40 (1):33-37 [Details]
	(2000)	'The relationship between increased folate catabolism and the increased requirement for folate in pregnancy' Higgins JR, Quinlivan EP, McPartlin J, Scott JM, Weir DG, Darling MR (2000) 'The relationship between increased folate catabolism and the increased requirement for folate in pregnancy'. An International Journal of Obstetrics and Gynaecology, 107 (9):1149-1154 [Details]
	(1999)	'Alternative forms of a novel aspartyl protease gene are differentially expressed in human gestational tissues' Moses EK, Freed KA, Higgins JR, Brennecke SP (1999) 'Alternative forms of a novel aspartyl protease gene are differentially expressed in human gestational tissues'. Human reproduction (Oxford, England), 5 (10):983-989 [Details]
	(1999)	''White coat hypertension' in pregnancy' Walker SP, Higgins JR, Permezel M, Brennecke SP, Phil D; (1999) ''White coat hypertension' in pregnancy'. Journal of Obstetrics and Gynaecology, 39 (2):200-202 [Details]
	(1999)	'Chronic hypertension and pregnancy' Higgins JR, Brennecke SP (1999) 'Chronic hypertension and pregnancy'. Hospital medicine (London, England : 1998), 35 :38-44 [Details]
	(1999)	'Nitric oxide in the uteroplacental, fetoplacental, and peripheral circulations in preeclampsia' Norris LA, Higgins JR, Darling MR, Walshe JJ, Bonnar J; (1999) 'Nitric oxide in the uteroplacental, fetoplacental, and peripheral circulations in preeclampsia'. Obstetrics and Gynecology, 93 (6):958-963 [Details]
	(1999)	'Maternal work and pregnancy' Walker SP, Higgins JR, Permezel M, Brennecke SP, Phil D; (1999) 'Maternal work and pregnancy'. Journal of Obstetrics and Gynaecology, 39 (2):144-151 [Details]
	(1998)	'Pre-eclampsia and eclampsia: magnesium salts for all?' Higgins JR, Brennecke SP; (1998) 'Pre-eclampsia and eclampsia: magnesium salts for all?'. The Medical Journal of Australia, 168 (4):151-152 [Details]
	(1998)	'Pre-eclampsia--still a disease of theories?' Higgins JR, Brennecke SP; (1998) 'Pre-eclampsia--still a disease of theories?'. Obstetrics and Gynecology, 10 (2):129-133 [Details]
	(1998)	'The diastolic debate: is it time to discard Korotkoff phase IV in favour of phase V for blood pressure measurements in pregnancy?' Walker SP, Higgins JR, Brennecke SP; (1998) 'The diastolic debate: is it time to discard Korotkoff phase IV in favour of phase V for blood pressure measurements in pregnancy?'. The Medical Journal of Australia, 169 (4):203-205 [Details]
	(1998)	'Re: Which Korotkoff sound should be used for diastolic blood pressure in pregnancy?' Higgins JR, Walker SP, Brennecke SP; (1998) 'Re: Which Korotkoff sound should be used for diastolic blood pressure in pregnancy?'. Journal of Obstetrics and Gynaecology, 38 (4):480-481 [Details]
	(1998)	'Ambulatory blood pressure monitoring in pregnancy' Walker SP, Higgins JR, Brennecke SP; (1998) 'Ambulatory blood pressure monitoring in pregnancy'. Obstetrics and Gynecology, 53 (10):636-644 [Details]
	(1998)	'Hemostasis in the uteroplacental and peripheral circulations in normotensive and pre-eclamptic pregnancies' Higgins JR, Walshe JJ, Darling MR, Norris L, Bonnar J (1998) 'Hemostasis in the uteroplacental and peripheral circulations in normotensive and pre-eclamptic pregnancies'. American Journal of Obstetrics and Gynaecology, 179 (2):520-526 [Details]
	(1998)	'Circulating vascular cell adhesion molecule-1 in pre-eclampsia, gestational hypertension, and normal pregnancy: evidence of selective dysregulation of vascular cell adhesion molecule-1 homeostasis in pre-eclampsia' Higgins JR, Papayianni A, Brady HR, Darling MR, Walshe JJ (1998) 'Circulating vascular cell adhesion molecule-1 in pre-eclampsia, gestational hypertension, and normal pregnancy: evidence of selective dysregulation of vascular cell adhesion molecule-1 homeostasis in pre-eclampsia'. American Journal of Obstetrics and Gynaecology, 179 (2):464-469 [Details]
	(1998)	'Circulating adhesion molecules in pre-eclampsia, gestational hypertension and normal pregnancy: evidence for selective dysfunction of VCAM-1 homeostasis in pre-eclampsia' Higgins J.R., Papayianni A., Brady H.R., Darling M.R.N., Walsh J.J.; (1998) 'Circulating adhesion molecules in pre-eclampsia, gestational hypertension and normal pregnancy: evidence for selective dysfunction of VCAM-1 homeostasis in pre-eclampsia'. American Journal Obstet Gynecol, * (179):464-469 [Details]
	(1997)	'Can 24-hour ambulatory blood pressure predict the development of hypertension in primgravidae?' Higgins J.R., Walshe J.J., Halligan A., O'Brien E., Conroy R., Darling M.; (1997) 'Can 24-hour ambulatory blood pressure predict the development of hypertension in primgravidae?'. British Journal Obstetrics and Gynaecology, * (104):356-362 [Details]
	(1997)	'Liver function tests in pre-eclampsia: importance of comparison with a reference range derived for normal pregnancy' Higgins JR, Walshe JJ, Darling MR (1997) 'Liver function tests in pre-eclampsia: importance of comparison with a reference range derived for normal pregnancy'. Journal of Obstetrics and Gynaecology, 104 (10) [Details]
	(1996)	'Maternal and neonatal hyponatraemia: a comparison of Hartmanns solution with 5% dextrose for the delivery of oxytocin in labour' Higgins J, Gleeson R, Holohan M, Cooney C, Darling M; (1996) 'Maternal and neonatal hyponatraemia: a comparison of Hartmanns solution with 5% dextrose for the delivery of oxytocin in labour'. Obstetrics and Gynecology, 68 (1-2):47-48 [Details]
	(1995)	'The definition of pre-eclampsia' Higgins JR, Byrne P (1995) 'The definition of pre-eclampsia'. Journal of Obstetrics and Gynaecology, 102 (7):586-587 [Details]
	(1995)	'Hormonal treatment of endometrial sarcoma - a case report' Hickey K, HigginsJ, Moriarty M, McGuinness E (1995) 'Hormonal treatment of endometrial sarcoma - a case report'. J Obstet Gynaecol, 15 :59-60 [Details]
	(1995)	'Hypertension in pregnancy - an unsolved problem' Higgins J (1995) 'Hypertension in pregnancy - an unsolved problem'. Irish Doctor, 7 (10):28-31 [Details]
	(1994)	'CLASP - Millstone or milestone? (Editorial to accompany the publication of the CLASP trial)' Darling M., Higgins, J. R.; (1994) 'CLASP - Millstone or milestone? (Editorial to accompany the publication of the CLASP trial)'. Lancet, * (343):616-661 [Details]
	(1987)	'Public attitudes to kidney donation' Higgins JR, Gaine SP, Chan K, Lam J (1987) 'Public attitudes to kidney donation'. Irish Medical Journal, 80 (11) [Details]

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