Thrombomodulin Ala455Val dimorphism is not associated with pre-eclampsia in Australian and New Zealand women

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TY  - JOUR
  - Borg, AJ,Higgins, JR,Brennecke, SP,Moses, EK
  - 2002
  - February
  - Gynecologic And Obstetric Investigation
  - Thrombomodulin Ala455Val dimorphism is not associated with pre-eclampsia in Australian and New Zealand women
  - Validated
  - ()
  - thrombomodulin polymorphism pre-eclampsia MYOCARDIAL-INFARCTION PREECLAMPSIA GENE RISK FIBRINOLYSIS HYPERTENSION POLYMORPHISM
  - 54
  - 43
  - 45
  - Thrombomodulin plays an important role in thromboresistance. A common mutation of the gene at amino acid 455 producing valine instead of alanine has been implicated as being a risk factor in myocardial infarction and chronic heart disease. However, its link with pre-eclampsia remains controversial. This report explores the Ala455Val point mutation in 280 women as a predictor of pre-eclampsia with the conclusion that in this regard, the dimorphism is essentially neutral. Copyright (C) 2002 S. KargerAG, Basel.
DA  - 2002/02
ER  - 
@article{V43338112,
   = {Borg,  AJ and Higgins,  JR and Brennecke,  SP and Moses,  EK },
   = {2002},
   = {February},
   = {Gynecologic And Obstetric Investigation},
   = {Thrombomodulin Ala455Val dimorphism is not associated with pre-eclampsia in Australian and New Zealand women},
   = {Validated},
   = {()},
   = {thrombomodulin polymorphism pre-eclampsia MYOCARDIAL-INFARCTION PREECLAMPSIA GENE RISK FIBRINOLYSIS HYPERTENSION POLYMORPHISM},
   = {54},
  pages = {43--45},
   = {{Thrombomodulin plays an important role in thromboresistance. A common mutation of the gene at amino acid 455 producing valine instead of alanine has been implicated as being a risk factor in myocardial infarction and chronic heart disease. However, its link with pre-eclampsia remains controversial. This report explores the Ala455Val point mutation in 280 women as a predictor of pre-eclampsia with the conclusion that in this regard, the dimorphism is essentially neutral. Copyright (C) 2002 S. KargerAG, Basel.}},
  source = {IRIS}
}
AUTHORSBorg, AJ,Higgins, JR,Brennecke, SP,Moses, EK
YEAR2002
MONTHFebruary
JOURNAL_CODEGynecologic And Obstetric Investigation
TITLEThrombomodulin Ala455Val dimorphism is not associated with pre-eclampsia in Australian and New Zealand women
STATUSValidated
TIMES_CITED()
SEARCH_KEYWORDthrombomodulin polymorphism pre-eclampsia MYOCARDIAL-INFARCTION PREECLAMPSIA GENE RISK FIBRINOLYSIS HYPERTENSION POLYMORPHISM
VOLUME54
ISSUE
START_PAGE43
END_PAGE45
ABSTRACTThrombomodulin plays an important role in thromboresistance. A common mutation of the gene at amino acid 455 producing valine instead of alanine has been implicated as being a risk factor in myocardial infarction and chronic heart disease. However, its link with pre-eclampsia remains controversial. This report explores the Ala455Val point mutation in 280 women as a predictor of pre-eclampsia with the conclusion that in this regard, the dimorphism is essentially neutral. Copyright (C) 2002 S. KargerAG, Basel.
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