Leptin-deficient mice retain normal appetitive spatial learning yet exhibit marked increases in anxiety-related behaviours.

Typeset version

 

TY  - JOUR
  - Finger, BC; Dinan, TG; Cryan JF
  - 2010
  - April
  - Psychopharmacology
  - Leptin-deficient mice retain normal appetitive spatial learning yet exhibit marked increases in anxiety-related behaviours.
  - Validated
  - ()
  - The individual's emotional state influences food intake in both humans and rodents. Moreover, specific cognitive processes regulating the salient aspects of food reward are also critical for ingestive behaviour. However, the molecular mechanisms underlying such influence remain unclear. Genetic mouse models thus are important tools in dissecting the molecular and pathophysiological processes which cause complex human diseases. Leptin, encoded by the ob gene, plays an important part in the energy homeostasis and is critical for the development of obesity.
  - 10.1007/s00213-010-1858-z
DA  - 2010/04
ER  - 
@article{V16860366,
   = {Finger, BC and  Dinan, TG and  Cryan JF},
   = {2010},
   = {April},
   = {Psychopharmacology},
   = {Leptin-deficient mice retain normal appetitive spatial learning yet exhibit marked increases in anxiety-related behaviours.},
   = {Validated},
   = {()},
   = {{The individual's emotional state influences food intake in both humans and rodents. Moreover, specific cognitive processes regulating the salient aspects of food reward are also critical for ingestive behaviour. However, the molecular mechanisms underlying such influence remain unclear. Genetic mouse models thus are important tools in dissecting the molecular and pathophysiological processes which cause complex human diseases. Leptin, encoded by the ob gene, plays an important part in the energy homeostasis and is critical for the development of obesity.}},
   = {10.1007/s00213-010-1858-z},
  source = {IRIS}
}
AUTHORSFinger, BC; Dinan, TG; Cryan JF
YEAR2010
MONTHApril
JOURNAL_CODEPsychopharmacology
TITLELeptin-deficient mice retain normal appetitive spatial learning yet exhibit marked increases in anxiety-related behaviours.
STATUSValidated
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ABSTRACTThe individual's emotional state influences food intake in both humans and rodents. Moreover, specific cognitive processes regulating the salient aspects of food reward are also critical for ingestive behaviour. However, the molecular mechanisms underlying such influence remain unclear. Genetic mouse models thus are important tools in dissecting the molecular and pathophysiological processes which cause complex human diseases. Leptin, encoded by the ob gene, plays an important part in the energy homeostasis and is critical for the development of obesity.
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DOI_LINK10.1007/s00213-010-1858-z
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