Soluble mediators in plasma from irritable bowel syndrome patients excite rat submucosal neurons.

Typeset version

 

TY  - JOUR
  - O'Malley D, Buckley MM, McKernan DP, Quigley EM, Cryan JF, Dinan TG
  - 2014
  - August
  - Brain Behav Immun
  - Soluble mediators in plasma from irritable bowel syndrome patients excite rat submucosal neurons.
  - Validated
  - WOS: 12 ()
  - Episodic bouts of abdominal pain and altered bowel habit are characteristic of irritable bowel syndrome (IBS). Although a comprehensive understanding of IBS pathophysiology remains elusive, support is growing for a primary role for immune activation in disease severity as evidenced by altered cytokine profiles in IBS plasma. Additionally, aberrant stimulation of the stress axis is likely to result in altered plasma constituents.
  - 10.1016/j.bbi.2014.08.005
DA  - 2014/08
ER  - 
@article{V271226715,
   = {O'Malley D,  Buckley MM and  McKernan DP,  Quigley EM and  Cryan JF,  Dinan TG },
   = {2014},
   = {August},
   = {Brain Behav Immun},
   = {Soluble mediators in plasma from irritable bowel syndrome patients excite rat submucosal neurons.},
   = {Validated},
   = {WOS: 12 ()},
   = {{Episodic bouts of abdominal pain and altered bowel habit are characteristic of irritable bowel syndrome (IBS). Although a comprehensive understanding of IBS pathophysiology remains elusive, support is growing for a primary role for immune activation in disease severity as evidenced by altered cytokine profiles in IBS plasma. Additionally, aberrant stimulation of the stress axis is likely to result in altered plasma constituents.}},
   = {10.1016/j.bbi.2014.08.005},
  source = {IRIS}
}
AUTHORSO'Malley D, Buckley MM, McKernan DP, Quigley EM, Cryan JF, Dinan TG
YEAR2014
MONTHAugust
JOURNAL_CODEBrain Behav Immun
TITLESoluble mediators in plasma from irritable bowel syndrome patients excite rat submucosal neurons.
STATUSValidated
TIMES_CITEDWOS: 12 ()
SEARCH_KEYWORD
VOLUME
ISSUE
START_PAGE
END_PAGE
ABSTRACTEpisodic bouts of abdominal pain and altered bowel habit are characteristic of irritable bowel syndrome (IBS). Although a comprehensive understanding of IBS pathophysiology remains elusive, support is growing for a primary role for immune activation in disease severity as evidenced by altered cytokine profiles in IBS plasma. Additionally, aberrant stimulation of the stress axis is likely to result in altered plasma constituents.
PUBLISHER_LOCATION
ISBN_ISSN
EDITION
URL
DOI_LINK10.1016/j.bbi.2014.08.005
FUNDING_BODY
GRANT_DETAILS