IRIS publication 43334808
Chain reactions: Early-life stress alters the metabolic profile of plasma polyunsaturated fatty acids in adulthood
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TY - JOUR - Clarke, G,O'Mahony, SM,Hennessy, AA,Ross, P,Stanton, C,Cryan, JF,Dinan, TG - 2009 - May - Behavioural Brain Research - Chain reactions: Early-life stress alters the metabolic profile of plasma polyunsaturated fatty acids in adulthood - Validated - () - Stress Animal model Maternal separation Arachidonic acid Depression Gas chromatography IRRITABLE-BOWEL-SYNDROME MOOD DISORDERS MESSENGER-RNA ANIMAL-MODELS RATS DEPRESSION DEPRIVATION ILLNESSES RODENTS - 205 - 319 - 321 - The rat maternal separation paradigm can be used to examine the biological consequences of early-life stress. Immunomodulatory polyunsaturated fatty acids (PUFAs) have recently attracted attention in the study of stress-related disorders. We established the plasma PUFA profile of maternally separated rodents compared to controls. Our results identify a proinflammatory PUFA profile as a persistent consequence of early-life stress and suggest new avenues of investigation in stress-related disorders. (C) 2009 Elsevier B.V. All rights reserved. - DOI 10.1016/j.bbr.2009.07.008 DA - 2009/05 ER -
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@article{V43334808, = {Clarke, G and O'Mahony, SM and Hennessy, AA and Ross, P and Stanton, C and Cryan, JF and Dinan, TG }, = {2009}, = {May}, = {Behavioural Brain Research}, = {Chain reactions: Early-life stress alters the metabolic profile of plasma polyunsaturated fatty acids in adulthood}, = {Validated}, = {()}, = {Stress Animal model Maternal separation Arachidonic acid Depression Gas chromatography IRRITABLE-BOWEL-SYNDROME MOOD DISORDERS MESSENGER-RNA ANIMAL-MODELS RATS DEPRESSION DEPRIVATION ILLNESSES RODENTS}, = {205}, pages = {319--321}, = {{The rat maternal separation paradigm can be used to examine the biological consequences of early-life stress. Immunomodulatory polyunsaturated fatty acids (PUFAs) have recently attracted attention in the study of stress-related disorders. We established the plasma PUFA profile of maternally separated rodents compared to controls. Our results identify a proinflammatory PUFA profile as a persistent consequence of early-life stress and suggest new avenues of investigation in stress-related disorders. (C) 2009 Elsevier B.V. All rights reserved.}}, = {DOI 10.1016/j.bbr.2009.07.008}, source = {IRIS} }
Data as stored in IRIS
AUTHORS | Clarke, G,O'Mahony, SM,Hennessy, AA,Ross, P,Stanton, C,Cryan, JF,Dinan, TG | ||
YEAR | 2009 | ||
MONTH | May | ||
JOURNAL_CODE | Behavioural Brain Research | ||
TITLE | Chain reactions: Early-life stress alters the metabolic profile of plasma polyunsaturated fatty acids in adulthood | ||
STATUS | Validated | ||
TIMES_CITED | () | ||
SEARCH_KEYWORD | Stress Animal model Maternal separation Arachidonic acid Depression Gas chromatography IRRITABLE-BOWEL-SYNDROME MOOD DISORDERS MESSENGER-RNA ANIMAL-MODELS RATS DEPRESSION DEPRIVATION ILLNESSES RODENTS | ||
VOLUME | 205 | ||
ISSUE | |||
START_PAGE | 319 | ||
END_PAGE | 321 | ||
ABSTRACT | The rat maternal separation paradigm can be used to examine the biological consequences of early-life stress. Immunomodulatory polyunsaturated fatty acids (PUFAs) have recently attracted attention in the study of stress-related disorders. We established the plasma PUFA profile of maternally separated rodents compared to controls. Our results identify a proinflammatory PUFA profile as a persistent consequence of early-life stress and suggest new avenues of investigation in stress-related disorders. (C) 2009 Elsevier B.V. All rights reserved. | ||
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DOI_LINK | DOI 10.1016/j.bbr.2009.07.008 | ||
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