IRIS publication 70177620
Intestinal microsomal triglyceride transfer protein in type 2 diabetic and non-diabetic subjects: the relationship to triglyceride-rich postprandial lipoprotein composition.
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TY - JOUR - Phillips C, Mullan K, Owens D, Tomkin GH - 2006 - July - Atherosclerosis - Intestinal microsomal triglyceride transfer protein in type 2 diabetic and non-diabetic subjects: the relationship to triglyceride-rich postprandial lipoprotein composition. - Validated - () - 187 - 1 - 57 - 64 - Microsomal triglyceride transfer protein (MTP) is responsible for the assembly of the triglyceride-rich lipoproteins (TRLs) and is increased in diabetic animal models. Human intestinal MTP expression has not been previously reported. This study examined the relationship between intestinal MTP gene expression and postprandial TRL composition in diabetic and non-diabetic subjects. Since the MTP promoter region has a sterol response element the effect of statins on intestinal MTP mRNA was analysed. - 10.1016/j.atherosclerosis.2005.08.020 DA - 2006/07 ER -
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@article{V70177620, = {Phillips C, Mullan K and Owens D, Tomkin GH }, = {2006}, = {July}, = {Atherosclerosis}, = {Intestinal microsomal triglyceride transfer protein in type 2 diabetic and non-diabetic subjects: the relationship to triglyceride-rich postprandial lipoprotein composition.}, = {Validated}, = {()}, = {187}, = {1}, pages = {57--64}, = {{Microsomal triglyceride transfer protein (MTP) is responsible for the assembly of the triglyceride-rich lipoproteins (TRLs) and is increased in diabetic animal models. Human intestinal MTP expression has not been previously reported. This study examined the relationship between intestinal MTP gene expression and postprandial TRL composition in diabetic and non-diabetic subjects. Since the MTP promoter region has a sterol response element the effect of statins on intestinal MTP mRNA was analysed.}}, = {10.1016/j.atherosclerosis.2005.08.020}, source = {IRIS} }
Data as stored in IRIS
AUTHORS | Phillips C, Mullan K, Owens D, Tomkin GH | ||
YEAR | 2006 | ||
MONTH | July | ||
JOURNAL_CODE | Atherosclerosis | ||
TITLE | Intestinal microsomal triglyceride transfer protein in type 2 diabetic and non-diabetic subjects: the relationship to triglyceride-rich postprandial lipoprotein composition. | ||
STATUS | Validated | ||
TIMES_CITED | () | ||
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VOLUME | 187 | ||
ISSUE | 1 | ||
START_PAGE | 57 | ||
END_PAGE | 64 | ||
ABSTRACT | Microsomal triglyceride transfer protein (MTP) is responsible for the assembly of the triglyceride-rich lipoproteins (TRLs) and is increased in diabetic animal models. Human intestinal MTP expression has not been previously reported. This study examined the relationship between intestinal MTP gene expression and postprandial TRL composition in diabetic and non-diabetic subjects. Since the MTP promoter region has a sterol response element the effect of statins on intestinal MTP mRNA was analysed. | ||
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DOI_LINK | 10.1016/j.atherosclerosis.2005.08.020 | ||
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