IRIS publication 70177622
Low density lipoprotein non-esterified fatty acids and lipoprotein lipase in diabetes.
RIS format for Endnote and similar
TY - JOUR - Phillips C, Owens D, Collins P, Tomkin GH - 2005 - July - Atherosclerosis - Low density lipoprotein non-esterified fatty acids and lipoprotein lipase in diabetes. - Validated - () - 181 - 1 - 109 - 114 - Fatty acid metabolism is disturbed in poorly controlled diabetes. Low density lipoprotein (LDL) oxidation, thought to be an atherogenic modification, is partly dependent on LDL fatty acid content whether it be in the form of cholesteryl ester, phospholipids, triglyceride or non-esterified fatty acid (NEFA). Lipoprotein lipase (LPL) is deficient in diabetic patients. Lipoprotein lipase bound to LDL may facilitate cholesterol accumulation in the artery wall through the attachment of LDL to the proteoglycans expressed on endothelial cells and collagen. The purpose of this study was to examine the degree of binding of fatty acids and lipoprotein lipase to LDL in type 2 diabetic patients and to examine the relationship between non-esterified fatty acids attached to LDL and LDL oxidisability. - 10.1016/j.atherosclerosis.2004.12.033 DA - 2005/07 ER -
BIBTeX format for JabRef and similar
@article{V70177622, = {Phillips C, Owens D and Collins P, Tomkin GH }, = {2005}, = {July}, = {Atherosclerosis}, = {Low density lipoprotein non-esterified fatty acids and lipoprotein lipase in diabetes.}, = {Validated}, = {()}, = {181}, = {1}, pages = {109--114}, = {{Fatty acid metabolism is disturbed in poorly controlled diabetes. Low density lipoprotein (LDL) oxidation, thought to be an atherogenic modification, is partly dependent on LDL fatty acid content whether it be in the form of cholesteryl ester, phospholipids, triglyceride or non-esterified fatty acid (NEFA). Lipoprotein lipase (LPL) is deficient in diabetic patients. Lipoprotein lipase bound to LDL may facilitate cholesterol accumulation in the artery wall through the attachment of LDL to the proteoglycans expressed on endothelial cells and collagen. The purpose of this study was to examine the degree of binding of fatty acids and lipoprotein lipase to LDL in type 2 diabetic patients and to examine the relationship between non-esterified fatty acids attached to LDL and LDL oxidisability.}}, = {10.1016/j.atherosclerosis.2004.12.033}, source = {IRIS} }
Data as stored in IRIS
AUTHORS | Phillips C, Owens D, Collins P, Tomkin GH | ||
YEAR | 2005 | ||
MONTH | July | ||
JOURNAL_CODE | Atherosclerosis | ||
TITLE | Low density lipoprotein non-esterified fatty acids and lipoprotein lipase in diabetes. | ||
STATUS | Validated | ||
TIMES_CITED | () | ||
SEARCH_KEYWORD | |||
VOLUME | 181 | ||
ISSUE | 1 | ||
START_PAGE | 109 | ||
END_PAGE | 114 | ||
ABSTRACT | Fatty acid metabolism is disturbed in poorly controlled diabetes. Low density lipoprotein (LDL) oxidation, thought to be an atherogenic modification, is partly dependent on LDL fatty acid content whether it be in the form of cholesteryl ester, phospholipids, triglyceride or non-esterified fatty acid (NEFA). Lipoprotein lipase (LPL) is deficient in diabetic patients. Lipoprotein lipase bound to LDL may facilitate cholesterol accumulation in the artery wall through the attachment of LDL to the proteoglycans expressed on endothelial cells and collagen. The purpose of this study was to examine the degree of binding of fatty acids and lipoprotein lipase to LDL in type 2 diabetic patients and to examine the relationship between non-esterified fatty acids attached to LDL and LDL oxidisability. | ||
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DOI_LINK | 10.1016/j.atherosclerosis.2004.12.033 | ||
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