Why is celiac disease so common in Ireland?

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TY  - JOUR
  - Cronin, C. C.,Shanahan, F.
  - 2001
  - Why is celiac disease so common in Ireland?
  - Validated
  - ()
  - 44
  - 33
  - 342
  - 352342
  - Celiac disease (gluten sensitive enteropathy) is a condition affecting the small bowel, characterized by permanent intolerance to dietary gluten, and giving rise to varying degrees of malabsorption and diarrhea. With the advent of sensitive screening tests, the condition is being increasingly diagnosed. Celiac disease is more common in the Irish and in those of Irish descent. Simoons (1978, 1981) hypothesized that the present-day prevalence of celiac disease across Europe is related to the interaction between genetic gradients, largely determined by the advance of agriculture, and historical patterns of cereal ingestion. This essay examines Simoons' hypothesis as it relates to Ireland, reviews the ethnic and genetic mix of those living on the island of Ireland and aspects of Irish dietary history and considers how these factors may have combined to result in a high frequency of celiac disease.Celiac disease (gluten sensitive enteropathy) is a condition affecting the small bowel, characterized by permanent intolerance to dietary gluten, and giving rise to varying degrees of malabsorption and diarrhea. With the advent of sensitive screening tests, the condition is being increasingly diagnosed. Celiac disease is more common in the Irish and in those of Irish descent. Simoons (1978, 1981) hypothesized that the present-day prevalence of celiac disease across Europe is related to the interaction between genetic gradients, largely determined by the advance of agriculture, and historical patterns of cereal ingestion. This essay examines Simoons' hypothesis as it relates to Ireland, reviews the ethnic and genetic mix of those living on the island of Ireland and aspects of Irish dietary history and considers how these factors may have combined to result in a high frequency of celiac disease.
  - 0031-59820031-5982
  - ://WOS:000169935900003://WOS:000169935900003
DA  - 2001/NaN
ER  - 
@article{V235379626,
   = {Cronin,  C. C. and Shanahan,  F. },
   = {2001},
   = {Why is celiac disease so common in Ireland?},
   = {Validated},
   = {()},
   = {44},
   = {33},
  pages = {342--352342},
   = {{Celiac disease (gluten sensitive enteropathy) is a condition affecting the small bowel, characterized by permanent intolerance to dietary gluten, and giving rise to varying degrees of malabsorption and diarrhea. With the advent of sensitive screening tests, the condition is being increasingly diagnosed. Celiac disease is more common in the Irish and in those of Irish descent. Simoons (1978, 1981) hypothesized that the present-day prevalence of celiac disease across Europe is related to the interaction between genetic gradients, largely determined by the advance of agriculture, and historical patterns of cereal ingestion. This essay examines Simoons' hypothesis as it relates to Ireland, reviews the ethnic and genetic mix of those living on the island of Ireland and aspects of Irish dietary history and considers how these factors may have combined to result in a high frequency of celiac disease.Celiac disease (gluten sensitive enteropathy) is a condition affecting the small bowel, characterized by permanent intolerance to dietary gluten, and giving rise to varying degrees of malabsorption and diarrhea. With the advent of sensitive screening tests, the condition is being increasingly diagnosed. Celiac disease is more common in the Irish and in those of Irish descent. Simoons (1978, 1981) hypothesized that the present-day prevalence of celiac disease across Europe is related to the interaction between genetic gradients, largely determined by the advance of agriculture, and historical patterns of cereal ingestion. This essay examines Simoons' hypothesis as it relates to Ireland, reviews the ethnic and genetic mix of those living on the island of Ireland and aspects of Irish dietary history and considers how these factors may have combined to result in a high frequency of celiac disease.}},
  issn = {0031-59820031-5982},
   = {://WOS:000169935900003://WOS:000169935900003},
  source = {IRIS}
}
AUTHORSCronin, C. C.,Shanahan, F.
YEAR2001
MONTH
JOURNAL_CODE
TITLEWhy is celiac disease so common in Ireland?
STATUSValidated
TIMES_CITED()
SEARCH_KEYWORD
VOLUME44
ISSUE33
START_PAGE342
END_PAGE352342
ABSTRACTCeliac disease (gluten sensitive enteropathy) is a condition affecting the small bowel, characterized by permanent intolerance to dietary gluten, and giving rise to varying degrees of malabsorption and diarrhea. With the advent of sensitive screening tests, the condition is being increasingly diagnosed. Celiac disease is more common in the Irish and in those of Irish descent. Simoons (1978, 1981) hypothesized that the present-day prevalence of celiac disease across Europe is related to the interaction between genetic gradients, largely determined by the advance of agriculture, and historical patterns of cereal ingestion. This essay examines Simoons' hypothesis as it relates to Ireland, reviews the ethnic and genetic mix of those living on the island of Ireland and aspects of Irish dietary history and considers how these factors may have combined to result in a high frequency of celiac disease.Celiac disease (gluten sensitive enteropathy) is a condition affecting the small bowel, characterized by permanent intolerance to dietary gluten, and giving rise to varying degrees of malabsorption and diarrhea. With the advent of sensitive screening tests, the condition is being increasingly diagnosed. Celiac disease is more common in the Irish and in those of Irish descent. Simoons (1978, 1981) hypothesized that the present-day prevalence of celiac disease across Europe is related to the interaction between genetic gradients, largely determined by the advance of agriculture, and historical patterns of cereal ingestion. This essay examines Simoons' hypothesis as it relates to Ireland, reviews the ethnic and genetic mix of those living on the island of Ireland and aspects of Irish dietary history and considers how these factors may have combined to result in a high frequency of celiac disease.
PUBLISHER_LOCATION
ISBN_ISSN0031-59820031-5982
EDITION
URL://WOS:000169935900003://WOS:000169935900003
DOI_LINK
FUNDING_BODY
GRANT_DETAILS