IRIS publication 235379998
Non-Linkage of a T-Cell Receptor-Gamma Chain Microsatellite (D7s485) to Rheumatoid-Arthritis, in Multiplex Families
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TY - JOUR - Mcdermott, M.,Hsu, C.,Molloy, M. G.,Mulcahy, B.,Phelan, M.,Shanahan, F.,Ogara, F.,Adams, C.,Rubin, L. A.,Clegg, D. O.,Husebye, D.,Amos, C. I.,Ward, R. H.,Kastner, D. L. - 1995 - February - Non-Linkage of a T-Cell Receptor-Gamma Chain Microsatellite (D7s485) to Rheumatoid-Arthritis, in Multiplex Families - Validated - () - 8 - 11 - 131 - 138131 - A highly informative microsatellite marker, D7S485, from the T-cell receptor gamma (TCRG) locus, has been used to study segregation of TCRG genes in 26 multiplex rheumatoid arthritis (RA) families. We used the sib-pair method to assess excess identity-by-descent sharing among affected members in these families and the LINKAGE package of programs was used to calculate two-point lod scores far the D7S485 marker. There was no evidence for segregation of TCRG genes with RA in affected siblings and significantly negative lad scores were obtained from Linkage analyses using bath autosomal dominant and recessive models of inheritance.A highly informative microsatellite marker, D7S485, from the T-cell receptor gamma (TCRG) locus, has been used to study segregation of TCRG genes in 26 multiplex rheumatoid arthritis (RA) families. We used the sib-pair method to assess excess identity-by-descent sharing among affected members in these families and the LINKAGE package of programs was used to calculate two-point lod scores far the D7S485 marker. There was no evidence for segregation of TCRG genes with RA in affected siblings and significantly negative lad scores were obtained from Linkage analyses using bath autosomal dominant and recessive models of inheritance. - 0896-84110896-8411 - ://WOS:A1995QF80900010://WOS:A1995QF80900010 DA - 1995/02 ER -
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@article{V235379998, = {Mcdermott, M. and Hsu, C. and Molloy, M. G. and Mulcahy, B. and Phelan, M. and Shanahan, F. and Ogara, F. and Adams, C. and Rubin, L. A. and Clegg, D. O. and Husebye, D. and Amos, C. I. and Ward, R. H. and Kastner, D. L. }, = {1995}, = {February}, = {Non-Linkage of a T-Cell Receptor-Gamma Chain Microsatellite (D7s485) to Rheumatoid-Arthritis, in Multiplex Families}, = {Validated}, = {()}, = {8}, = {11}, pages = {131--138131}, = {{A highly informative microsatellite marker, D7S485, from the T-cell receptor gamma (TCRG) locus, has been used to study segregation of TCRG genes in 26 multiplex rheumatoid arthritis (RA) families. We used the sib-pair method to assess excess identity-by-descent sharing among affected members in these families and the LINKAGE package of programs was used to calculate two-point lod scores far the D7S485 marker. There was no evidence for segregation of TCRG genes with RA in affected siblings and significantly negative lad scores were obtained from Linkage analyses using bath autosomal dominant and recessive models of inheritance.A highly informative microsatellite marker, D7S485, from the T-cell receptor gamma (TCRG) locus, has been used to study segregation of TCRG genes in 26 multiplex rheumatoid arthritis (RA) families. We used the sib-pair method to assess excess identity-by-descent sharing among affected members in these families and the LINKAGE package of programs was used to calculate two-point lod scores far the D7S485 marker. There was no evidence for segregation of TCRG genes with RA in affected siblings and significantly negative lad scores were obtained from Linkage analyses using bath autosomal dominant and recessive models of inheritance.}}, issn = {0896-84110896-8411}, = {://WOS:A1995QF80900010://WOS:A1995QF80900010}, source = {IRIS} }
Data as stored in IRIS
AUTHORS | Mcdermott, M.,Hsu, C.,Molloy, M. G.,Mulcahy, B.,Phelan, M.,Shanahan, F.,Ogara, F.,Adams, C.,Rubin, L. A.,Clegg, D. O.,Husebye, D.,Amos, C. I.,Ward, R. H.,Kastner, D. L. | ||
YEAR | 1995 | ||
MONTH | February | ||
JOURNAL_CODE | |||
TITLE | Non-Linkage of a T-Cell Receptor-Gamma Chain Microsatellite (D7s485) to Rheumatoid-Arthritis, in Multiplex Families | ||
STATUS | Validated | ||
TIMES_CITED | () | ||
SEARCH_KEYWORD | |||
VOLUME | 8 | ||
ISSUE | 11 | ||
START_PAGE | 131 | ||
END_PAGE | 138131 | ||
ABSTRACT | A highly informative microsatellite marker, D7S485, from the T-cell receptor gamma (TCRG) locus, has been used to study segregation of TCRG genes in 26 multiplex rheumatoid arthritis (RA) families. We used the sib-pair method to assess excess identity-by-descent sharing among affected members in these families and the LINKAGE package of programs was used to calculate two-point lod scores far the D7S485 marker. There was no evidence for segregation of TCRG genes with RA in affected siblings and significantly negative lad scores were obtained from Linkage analyses using bath autosomal dominant and recessive models of inheritance.A highly informative microsatellite marker, D7S485, from the T-cell receptor gamma (TCRG) locus, has been used to study segregation of TCRG genes in 26 multiplex rheumatoid arthritis (RA) families. We used the sib-pair method to assess excess identity-by-descent sharing among affected members in these families and the LINKAGE package of programs was used to calculate two-point lod scores far the D7S485 marker. There was no evidence for segregation of TCRG genes with RA in affected siblings and significantly negative lad scores were obtained from Linkage analyses using bath autosomal dominant and recessive models of inheritance. | ||
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ISBN_ISSN | 0896-84110896-8411 | ||
EDITION | |||
URL | ://WOS:A1995QF80900010://WOS:A1995QF80900010 | ||
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