IRIS publication 235380085
Pathways of Activation of the Epstein-Barr-Virus Productive Cycle
RIS format for Endnote and similar
TY - JOUR - Sinclair, A. J.,Brimmell, M.,Shanahan, F.,Farrell, P. J. - 1991 - May - Pathways of Activation of the Epstein-Barr-Virus Productive Cycle - Validated - () - 65 - 55 - 2237 - 22442237 - The promoter for the 2.8-kb RNA of Epstein-Barr virus encoding BZLF1 and BRLF1 was identified and shown to be activated by both BZLF1 and BRLF1 but not by 12-O-tetradecanoylphorbol-13-acetate. Site-directed mutagenesis suggests that two binding sites for BZLF1 within the promoter contribute to the transactivation by BZLF1. The early kinetics of induction of the 2.8- and 1.0-kb RNAs encoding BZLF1 and BRLF1 in Akata cells treated with anti-immunoglobulin indicate that both RNAs appear within 60 min. The results indicate some likely pathways of activation of Epstein-Barr virus productive cycle gene expression.The promoter for the 2.8-kb RNA of Epstein-Barr virus encoding BZLF1 and BRLF1 was identified and shown to be activated by both BZLF1 and BRLF1 but not by 12-O-tetradecanoylphorbol-13-acetate. Site-directed mutagenesis suggests that two binding sites for BZLF1 within the promoter contribute to the transactivation by BZLF1. The early kinetics of induction of the 2.8- and 1.0-kb RNAs encoding BZLF1 and BRLF1 in Akata cells treated with anti-immunoglobulin indicate that both RNAs appear within 60 min. The results indicate some likely pathways of activation of Epstein-Barr virus productive cycle gene expression. - 0022-538X0022-538X - ://WOS:A1991FG77700011://WOS:A1991FG77700011 DA - 1991/05 ER -
BIBTeX format for JabRef and similar
@article{V235380085, = {Sinclair, A. J. and Brimmell, M. and Shanahan, F. and Farrell, P. J. }, = {1991}, = {May}, = {Pathways of Activation of the Epstein-Barr-Virus Productive Cycle}, = {Validated}, = {()}, = {65}, = {55}, pages = {2237--22442237}, = {{The promoter for the 2.8-kb RNA of Epstein-Barr virus encoding BZLF1 and BRLF1 was identified and shown to be activated by both BZLF1 and BRLF1 but not by 12-O-tetradecanoylphorbol-13-acetate. Site-directed mutagenesis suggests that two binding sites for BZLF1 within the promoter contribute to the transactivation by BZLF1. The early kinetics of induction of the 2.8- and 1.0-kb RNAs encoding BZLF1 and BRLF1 in Akata cells treated with anti-immunoglobulin indicate that both RNAs appear within 60 min. The results indicate some likely pathways of activation of Epstein-Barr virus productive cycle gene expression.The promoter for the 2.8-kb RNA of Epstein-Barr virus encoding BZLF1 and BRLF1 was identified and shown to be activated by both BZLF1 and BRLF1 but not by 12-O-tetradecanoylphorbol-13-acetate. Site-directed mutagenesis suggests that two binding sites for BZLF1 within the promoter contribute to the transactivation by BZLF1. The early kinetics of induction of the 2.8- and 1.0-kb RNAs encoding BZLF1 and BRLF1 in Akata cells treated with anti-immunoglobulin indicate that both RNAs appear within 60 min. The results indicate some likely pathways of activation of Epstein-Barr virus productive cycle gene expression.}}, issn = {0022-538X0022-538X}, = {://WOS:A1991FG77700011://WOS:A1991FG77700011}, source = {IRIS} }
Data as stored in IRIS
AUTHORS | Sinclair, A. J.,Brimmell, M.,Shanahan, F.,Farrell, P. J. | ||
YEAR | 1991 | ||
MONTH | May | ||
JOURNAL_CODE | |||
TITLE | Pathways of Activation of the Epstein-Barr-Virus Productive Cycle | ||
STATUS | Validated | ||
TIMES_CITED | () | ||
SEARCH_KEYWORD | |||
VOLUME | 65 | ||
ISSUE | 55 | ||
START_PAGE | 2237 | ||
END_PAGE | 22442237 | ||
ABSTRACT | The promoter for the 2.8-kb RNA of Epstein-Barr virus encoding BZLF1 and BRLF1 was identified and shown to be activated by both BZLF1 and BRLF1 but not by 12-O-tetradecanoylphorbol-13-acetate. Site-directed mutagenesis suggests that two binding sites for BZLF1 within the promoter contribute to the transactivation by BZLF1. The early kinetics of induction of the 2.8- and 1.0-kb RNAs encoding BZLF1 and BRLF1 in Akata cells treated with anti-immunoglobulin indicate that both RNAs appear within 60 min. The results indicate some likely pathways of activation of Epstein-Barr virus productive cycle gene expression.The promoter for the 2.8-kb RNA of Epstein-Barr virus encoding BZLF1 and BRLF1 was identified and shown to be activated by both BZLF1 and BRLF1 but not by 12-O-tetradecanoylphorbol-13-acetate. Site-directed mutagenesis suggests that two binding sites for BZLF1 within the promoter contribute to the transactivation by BZLF1. The early kinetics of induction of the 2.8- and 1.0-kb RNAs encoding BZLF1 and BRLF1 in Akata cells treated with anti-immunoglobulin indicate that both RNAs appear within 60 min. The results indicate some likely pathways of activation of Epstein-Barr virus productive cycle gene expression. | ||
PUBLISHER_LOCATION | |||
ISBN_ISSN | 0022-538X0022-538X | ||
EDITION | |||
URL | ://WOS:A1991FG77700011://WOS:A1991FG77700011 | ||
DOI_LINK | |||
FUNDING_BODY | |||
GRANT_DETAILS |