IRIS publication 179169603
Development of Stabilised Vaccines with Needle-Free Devices for Targeted Skin Immunization
RIS format for Endnote and similar
TY - JOUR - A. Crean, C. O’Mahony and A. C. Moore - 2010 - June - European Pharmaceutical Review - Development of Stabilised Vaccines with Needle-Free Devices for Targeted Skin Immunization - Published - 0 - microneedles, transdermal delivery, vaccine - 15 - 6 - 56 - 60 - Vaccination represents the primary public health measure to combat infectious diseases. However, limitations of cold-chain storage, vaccine wastage, hazardous sharps-waste and the requirements for trained personnel add significant and unsustainable financial and logistic costs to immunisation programmes. Developments of needle-free methods should aim to overcome these logistics issues from the very start of the vaccine production process. Dermal vaccine administration using microneedle-based devices promises to be one such needle-free method that addresses all of these issues. Methods of stabilisation of vaccines onto or incorporated into microneedles should be developed to permit seamless transition and cost-effectiveness from vaccine bulk-up to final product. This review examines recent developments in microneedle technology and highlights the current challenges to translate this technology into practice. DA - 2010/06 ER -
BIBTeX format for JabRef and similar
@article{V179169603, = {A. Crean, C. O’Mahony and A. C. Moore}, = {2010}, = {June}, = {European Pharmaceutical Review}, = {Development of Stabilised Vaccines with Needle-Free Devices for Targeted Skin Immunization}, = {Published}, = {0}, = {microneedles, transdermal delivery, vaccine}, = {15}, = {6}, pages = {56--60}, = {{Vaccination represents the primary public health measure to combat infectious diseases. However, limitations of cold-chain storage, vaccine wastage, hazardous sharps-waste and the requirements for trained personnel add significant and unsustainable financial and logistic costs to immunisation programmes. Developments of needle-free methods should aim to overcome these logistics issues from the very start of the vaccine production process. Dermal vaccine administration using microneedle-based devices promises to be one such needle-free method that addresses all of these issues. Methods of stabilisation of vaccines onto or incorporated into microneedles should be developed to permit seamless transition and cost-effectiveness from vaccine bulk-up to final product. This review examines recent developments in microneedle technology and highlights the current challenges to translate this technology into practice.}}, source = {IRIS} }
Data as stored in IRIS
AUTHORS | A. Crean, C. O’Mahony and A. C. Moore | ||
YEAR | 2010 | ||
MONTH | June | ||
JOURNAL | European Pharmaceutical Review | ||
TITLE | Development of Stabilised Vaccines with Needle-Free Devices for Targeted Skin Immunization | ||
STATUS | Published | ||
PEER_REVIEW | 0 | ||
SEARCH_KEYWORD | microneedles, transdermal delivery, vaccine | ||
VOLUME | 15 | ||
ISSUE | 6 | ||
START_PAGE | 56 | ||
END_PAGE | 60 | ||
ABSTRACT | Vaccination represents the primary public health measure to combat infectious diseases. However, limitations of cold-chain storage, vaccine wastage, hazardous sharps-waste and the requirements for trained personnel add significant and unsustainable financial and logistic costs to immunisation programmes. Developments of needle-free methods should aim to overcome these logistics issues from the very start of the vaccine production process. Dermal vaccine administration using microneedle-based devices promises to be one such needle-free method that addresses all of these issues. Methods of stabilisation of vaccines onto or incorporated into microneedles should be developed to permit seamless transition and cost-effectiveness from vaccine bulk-up to final product. This review examines recent developments in microneedle technology and highlights the current challenges to translate this technology into practice. | ||
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