TY  - JOUR
  - Cotter, PD,O'Reilly, K,Hill, C
  - 2001
  - January
  - Journal of Food Protection
  - Role of the glutamate decarboxylase acid resistance system in the survival of Listeria monocytogenes LO28 in low pH foods
  - Validated
  - ()
  - ESCHERICHIA-COLI O157-H7 SALMONELLA-TYPHIMURIUM UNITED-STATES TOLERANCE GROWTH ADAPTATION IDENTIFICATION FERMENTATION ACIDULANTS RESPONSES
  - 64
  - 1362
  - 1368
  - The glutamate decarboxylase (GAD) acid resistance system of the foodborne pathogen Listeria monocytogenes plays a major role in its survival at low pH. It was found that survival of the wild-type strain. LO28, in acidified reconstituted skim milk. diluted to reduce free glutamate levels. improves in response to supplementation with monosodium glutamate. A mutant, in which the two listerial GAD homologs have been deleted (and in which there is no discernible GAD activity), did not respond to glutamate supplementation and displayed greatly enhanced sensitivity in a number of low pH foods, even when levels of free glutamate were as low as 0.22 mM. We thus show that the GAD system plays a major role in the survival of L. monocytogenes in acidic foods even when levels of free glutamate are low.
DA  - 2001/01
ER  - 

@article{V146949419,
   = {Cotter,  PD and O'Reilly,  K and Hill,  C },
   = {2001},
   = {January},
   = {Journal of Food Protection},
   = {Role of the glutamate decarboxylase acid resistance system in the survival of Listeria monocytogenes LO28 in low pH foods},
   = {Validated},
   = {()},
   = {ESCHERICHIA-COLI O157-H7 SALMONELLA-TYPHIMURIUM UNITED-STATES TOLERANCE GROWTH ADAPTATION IDENTIFICATION FERMENTATION ACIDULANTS RESPONSES},
   = {64},
  pages = {1362--1368},
   = {{The glutamate decarboxylase (GAD) acid resistance system of the foodborne pathogen Listeria monocytogenes plays a major role in its survival at low pH. It was found that survival of the wild-type strain. LO28, in acidified reconstituted skim milk. diluted to reduce free glutamate levels. improves in response to supplementation with monosodium glutamate. A mutant, in which the two listerial GAD homologs have been deleted (and in which there is no discernible GAD activity), did not respond to glutamate supplementation and displayed greatly enhanced sensitivity in a number of low pH foods, even when levels of free glutamate were as low as 0.22 mM. We thus show that the GAD system plays a major role in the survival of L. monocytogenes in acidic foods even when levels of free glutamate are low.}},
  source = {IRIS}
}