The spiFEG Locus in Streptococcus infantarius subsp infantarius BAA-102 Confers Protection against Nisin U

Typeset version

 

TY  - JOUR
  - Draper, LA,Tagg, JR,Hill, C,Cotter, PD,Ross, RP
  - 2012
  - January
  - Antimicrobial Agents and Chemotherapy
  - The spiFEG Locus in Streptococcus infantarius subsp infantarius BAA-102 Confers Protection against Nisin U
  - Validated
  - ()
  - GRAM-POSITIVE PATHOGENS LACTOCOCCUS-LACTIS LISTERIA-MONOCYTOGENES LANTIBIOTIC NISIN INNATE RESISTANCE GENE-CLUSTER IMMUNITY BIOSYNTHESIS IDENTIFICATION ANTIBIOTICS
  - 56
  - 573
  - 578
  - Nisin U is a member of the extended nisin family of lantibiotics. Here we identify the presence of nisin U immunity gene homologues in Streptococcus infantarius subsp. infantarius BAA-102. Heterologous expression of these genes in Lactococcus lactis subsp. cremoris HP confers protection to nisin U and other members of the nisin family, thereby establishing that the recently identified phenomenon of resistance through immune mimicry also occurs with respect to nisin.
  - DOI 10.1128/AAC.05778-11
DA  - 2012/01
ER  - 
@article{V160748385,
   = {Draper,  LA and Tagg,  JR and Hill,  C and Cotter,  PD and Ross,  RP },
   = {2012},
   = {January},
   = {Antimicrobial Agents and Chemotherapy},
   = {The spiFEG Locus in Streptococcus infantarius subsp infantarius BAA-102 Confers Protection against Nisin U},
   = {Validated},
   = {()},
   = {GRAM-POSITIVE PATHOGENS LACTOCOCCUS-LACTIS LISTERIA-MONOCYTOGENES LANTIBIOTIC NISIN INNATE RESISTANCE GENE-CLUSTER IMMUNITY BIOSYNTHESIS IDENTIFICATION ANTIBIOTICS},
   = {56},
  pages = {573--578},
   = {{Nisin U is a member of the extended nisin family of lantibiotics. Here we identify the presence of nisin U immunity gene homologues in Streptococcus infantarius subsp. infantarius BAA-102. Heterologous expression of these genes in Lactococcus lactis subsp. cremoris HP confers protection to nisin U and other members of the nisin family, thereby establishing that the recently identified phenomenon of resistance through immune mimicry also occurs with respect to nisin.}},
   = {DOI 10.1128/AAC.05778-11},
  source = {IRIS}
}
AUTHORSDraper, LA,Tagg, JR,Hill, C,Cotter, PD,Ross, RP
YEAR2012
MONTHJanuary
JOURNAL_CODEAntimicrobial Agents and Chemotherapy
TITLEThe spiFEG Locus in Streptococcus infantarius subsp infantarius BAA-102 Confers Protection against Nisin U
STATUSValidated
TIMES_CITED()
SEARCH_KEYWORDGRAM-POSITIVE PATHOGENS LACTOCOCCUS-LACTIS LISTERIA-MONOCYTOGENES LANTIBIOTIC NISIN INNATE RESISTANCE GENE-CLUSTER IMMUNITY BIOSYNTHESIS IDENTIFICATION ANTIBIOTICS
VOLUME56
ISSUE
START_PAGE573
END_PAGE578
ABSTRACTNisin U is a member of the extended nisin family of lantibiotics. Here we identify the presence of nisin U immunity gene homologues in Streptococcus infantarius subsp. infantarius BAA-102. Heterologous expression of these genes in Lactococcus lactis subsp. cremoris HP confers protection to nisin U and other members of the nisin family, thereby establishing that the recently identified phenomenon of resistance through immune mimicry also occurs with respect to nisin.
PUBLISHER_LOCATION
ISBN_ISSN
EDITION
URL
DOI_LINKDOI 10.1128/AAC.05778-11
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