IRIS publication 160748385
The spiFEG Locus in Streptococcus infantarius subsp infantarius BAA-102 Confers Protection against Nisin U
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TY - JOUR - Draper, LA,Tagg, JR,Hill, C,Cotter, PD,Ross, RP - 2012 - January - Antimicrobial Agents and Chemotherapy - The spiFEG Locus in Streptococcus infantarius subsp infantarius BAA-102 Confers Protection against Nisin U - Validated - () - GRAM-POSITIVE PATHOGENS LACTOCOCCUS-LACTIS LISTERIA-MONOCYTOGENES LANTIBIOTIC NISIN INNATE RESISTANCE GENE-CLUSTER IMMUNITY BIOSYNTHESIS IDENTIFICATION ANTIBIOTICS - 56 - 573 - 578 - Nisin U is a member of the extended nisin family of lantibiotics. Here we identify the presence of nisin U immunity gene homologues in Streptococcus infantarius subsp. infantarius BAA-102. Heterologous expression of these genes in Lactococcus lactis subsp. cremoris HP confers protection to nisin U and other members of the nisin family, thereby establishing that the recently identified phenomenon of resistance through immune mimicry also occurs with respect to nisin. - DOI 10.1128/AAC.05778-11 DA - 2012/01 ER -
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@article{V160748385, = {Draper, LA and Tagg, JR and Hill, C and Cotter, PD and Ross, RP }, = {2012}, = {January}, = {Antimicrobial Agents and Chemotherapy}, = {The spiFEG Locus in Streptococcus infantarius subsp infantarius BAA-102 Confers Protection against Nisin U}, = {Validated}, = {()}, = {GRAM-POSITIVE PATHOGENS LACTOCOCCUS-LACTIS LISTERIA-MONOCYTOGENES LANTIBIOTIC NISIN INNATE RESISTANCE GENE-CLUSTER IMMUNITY BIOSYNTHESIS IDENTIFICATION ANTIBIOTICS}, = {56}, pages = {573--578}, = {{Nisin U is a member of the extended nisin family of lantibiotics. Here we identify the presence of nisin U immunity gene homologues in Streptococcus infantarius subsp. infantarius BAA-102. Heterologous expression of these genes in Lactococcus lactis subsp. cremoris HP confers protection to nisin U and other members of the nisin family, thereby establishing that the recently identified phenomenon of resistance through immune mimicry also occurs with respect to nisin.}}, = {DOI 10.1128/AAC.05778-11}, source = {IRIS} }
Data as stored in IRIS
AUTHORS | Draper, LA,Tagg, JR,Hill, C,Cotter, PD,Ross, RP | ||
YEAR | 2012 | ||
MONTH | January | ||
JOURNAL_CODE | Antimicrobial Agents and Chemotherapy | ||
TITLE | The spiFEG Locus in Streptococcus infantarius subsp infantarius BAA-102 Confers Protection against Nisin U | ||
STATUS | Validated | ||
TIMES_CITED | () | ||
SEARCH_KEYWORD | GRAM-POSITIVE PATHOGENS LACTOCOCCUS-LACTIS LISTERIA-MONOCYTOGENES LANTIBIOTIC NISIN INNATE RESISTANCE GENE-CLUSTER IMMUNITY BIOSYNTHESIS IDENTIFICATION ANTIBIOTICS | ||
VOLUME | 56 | ||
ISSUE | |||
START_PAGE | 573 | ||
END_PAGE | 578 | ||
ABSTRACT | Nisin U is a member of the extended nisin family of lantibiotics. Here we identify the presence of nisin U immunity gene homologues in Streptococcus infantarius subsp. infantarius BAA-102. Heterologous expression of these genes in Lactococcus lactis subsp. cremoris HP confers protection to nisin U and other members of the nisin family, thereby establishing that the recently identified phenomenon of resistance through immune mimicry also occurs with respect to nisin. | ||
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DOI_LINK | DOI 10.1128/AAC.05778-11 | ||
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