IRIS publication 241507054
Virulence aspects of Listeria monocytogenes LO28 high pressure-resistant variants.
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TY - JOUR - Van Boeijen IK, Casey PG, Hill C, Moezelaar R, Zwietering MH, Gahan CG, Abee T - 2013 - June - Microbial Pathogenesis - Virulence aspects of Listeria monocytogenes LO28 high pressure-resistant variants. - Validated - () - 59-60 - 48 - 51 - High pressure treatment is a novel food processing approach for reducing pathogens in foods and food ingredients. However, relatively little is known about the pathogenic potential of organisms that survive the treatment. Twelve previously isolated and characterized variants of Listeria monocytogenes LO28 obtained after a high pressure treatment were assessed for their virulence potential and antibiotic susceptibility. Ten variants showed attenuated virulence while two variants retained full virulence in a mouse model of infection. Seven of the attenuated variants demonstrated a reduction in virulence factor activity. Compared to the wild type, all variants exhibited similar or increased susceptibility to multiple antibiotics commonly used in listeriosis treatment. - 10.1016/j.micpath.2013.04.007 DA - 2013/06 ER -
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@article{V241507054, = {Van Boeijen IK, Casey PG and Hill C, Moezelaar R and Zwietering MH, Gahan CG and Abee T }, = {2013}, = {June}, = {Microbial Pathogenesis}, = {Virulence aspects of Listeria monocytogenes LO28 high pressure-resistant variants.}, = {Validated}, = {()}, = {59-60}, pages = {48--51}, = {{High pressure treatment is a novel food processing approach for reducing pathogens in foods and food ingredients. However, relatively little is known about the pathogenic potential of organisms that survive the treatment. Twelve previously isolated and characterized variants of Listeria monocytogenes LO28 obtained after a high pressure treatment were assessed for their virulence potential and antibiotic susceptibility. Ten variants showed attenuated virulence while two variants retained full virulence in a mouse model of infection. Seven of the attenuated variants demonstrated a reduction in virulence factor activity. Compared to the wild type, all variants exhibited similar or increased susceptibility to multiple antibiotics commonly used in listeriosis treatment.}}, = {10.1016/j.micpath.2013.04.007}, source = {IRIS} }
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AUTHORS | Van Boeijen IK, Casey PG, Hill C, Moezelaar R, Zwietering MH, Gahan CG, Abee T | ||
YEAR | 2013 | ||
MONTH | June | ||
JOURNAL_CODE | Microbial Pathogenesis | ||
TITLE | Virulence aspects of Listeria monocytogenes LO28 high pressure-resistant variants. | ||
STATUS | Validated | ||
TIMES_CITED | () | ||
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VOLUME | 59-60 | ||
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START_PAGE | 48 | ||
END_PAGE | 51 | ||
ABSTRACT | High pressure treatment is a novel food processing approach for reducing pathogens in foods and food ingredients. However, relatively little is known about the pathogenic potential of organisms that survive the treatment. Twelve previously isolated and characterized variants of Listeria monocytogenes LO28 obtained after a high pressure treatment were assessed for their virulence potential and antibiotic susceptibility. Ten variants showed attenuated virulence while two variants retained full virulence in a mouse model of infection. Seven of the attenuated variants demonstrated a reduction in virulence factor activity. Compared to the wild type, all variants exhibited similar or increased susceptibility to multiple antibiotics commonly used in listeriosis treatment. | ||
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DOI_LINK | 10.1016/j.micpath.2013.04.007 | ||
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