TY  - JOUR
  - Mathur, H,O'Connor, PM,Hill, C,Cotter, PD,Ross, RP
  - 2013
  - June
  - Antimicrobial Agents and Chemotherapy
  - Analysis of Anti-Clostridium difficile Activity of Thuricin CD, Vancomycin, Metronidazole, Ramoplanin, and Actagardine, both Singly and in Paired Combinations
  - Validated
  - WOS: 34 ()
  - IN-VITRO NARROW-SPECTRUM INFECTION DISEASES SUSCEPTIBILITY SYNERGY SOCIETY COLONIZATION RECURRENCE GUIDELINES
  - 57
  - 2882
  - 2886
  - Due to the ongoing problem of recurrence of Clostridium difficile-associated diarrhea following antibiotic treatment, there is an urgent need for alternative treatment options. We assessed the MICs of five antimicrobials singly and in combinations against a range of C. difficile clinical isolates. Ramoplanin-actagardine combinations were particularly effective, with partial synergistic/additive effects observed against 61.5% of C. difficile strains tested.
  - 10.1128/AAC.00261-13
DA  - 2013/06
ER  - 

@article{V243941534,
   = {Mathur,  H and O'Connor,  PM and Hill,  C and Cotter,  PD and Ross,  RP },
   = {2013},
   = {June},
   = {Antimicrobial Agents and Chemotherapy},
   = {Analysis of Anti-Clostridium difficile Activity of Thuricin CD, Vancomycin, Metronidazole, Ramoplanin, and Actagardine, both Singly and in Paired Combinations},
   = {Validated},
   = {WOS: 34 ()},
   = {IN-VITRO NARROW-SPECTRUM INFECTION DISEASES SUSCEPTIBILITY SYNERGY SOCIETY COLONIZATION RECURRENCE GUIDELINES},
   = {57},
  pages = {2882--2886},
   = {{Due to the ongoing problem of recurrence of Clostridium difficile-associated diarrhea following antibiotic treatment, there is an urgent need for alternative treatment options. We assessed the MICs of five antimicrobials singly and in combinations against a range of C. difficile clinical isolates. Ramoplanin-actagardine combinations were particularly effective, with partial synergistic/additive effects observed against 61.5% of C. difficile strains tested.}},
   = {10.1128/AAC.00261-13},
  source = {IRIS}
}