IRIS publication 268806212
Altered FXR signaling is associated with bile acid dysmetabolism in short bowel syndrome-associated liver disease.
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TY - JOUR - Pereira-Fantini PM, Lapthorne S, Joyce SA, Dellios NL, Wilson G, Fouhy F, Thomas SL, Scurr M, Hill C, Gahan CG, Cotter PD, Fuller PJ, Hardikar W, Bines JE - 2014 - July - Journal of hepatology - Altered FXR signaling is associated with bile acid dysmetabolism in short bowel syndrome-associated liver disease. - Validated - Altmetric: 1 () - Despite the mortality associated with liver disease observed in patients with short bowel syndrome (SBS), mechanisms underlying the development of SBS-associated liver disease (SBS-ALD) are poorly understood. This study examines the impact of bacterially-mediated bile acid (BA) dysmetabolism on FXR signaling pathways and clinical outcome in a piglet model of SBS-ALD. - 10.1016/j.jhep.2014.06.025 DA - 2014/07 ER -
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@article{V268806212, = {Pereira-Fantini PM, Lapthorne S and Joyce SA, Dellios NL and Wilson G, Fouhy F and Thomas SL, Scurr M and Hill C, Gahan CG and Cotter PD, Fuller PJ and Hardikar W, Bines JE }, = {2014}, = {July}, = {Journal of hepatology}, = {Altered FXR signaling is associated with bile acid dysmetabolism in short bowel syndrome-associated liver disease.}, = {Validated}, = {Altmetric: 1 ()}, = {{Despite the mortality associated with liver disease observed in patients with short bowel syndrome (SBS), mechanisms underlying the development of SBS-associated liver disease (SBS-ALD) are poorly understood. This study examines the impact of bacterially-mediated bile acid (BA) dysmetabolism on FXR signaling pathways and clinical outcome in a piglet model of SBS-ALD.}}, = {10.1016/j.jhep.2014.06.025}, source = {IRIS} }
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AUTHORS | Pereira-Fantini PM, Lapthorne S, Joyce SA, Dellios NL, Wilson G, Fouhy F, Thomas SL, Scurr M, Hill C, Gahan CG, Cotter PD, Fuller PJ, Hardikar W, Bines JE | ||
YEAR | 2014 | ||
MONTH | July | ||
JOURNAL_CODE | Journal of hepatology | ||
TITLE | Altered FXR signaling is associated with bile acid dysmetabolism in short bowel syndrome-associated liver disease. | ||
STATUS | Validated | ||
TIMES_CITED | Altmetric: 1 () | ||
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ABSTRACT | Despite the mortality associated with liver disease observed in patients with short bowel syndrome (SBS), mechanisms underlying the development of SBS-associated liver disease (SBS-ALD) are poorly understood. This study examines the impact of bacterially-mediated bile acid (BA) dysmetabolism on FXR signaling pathways and clinical outcome in a piglet model of SBS-ALD. | ||
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DOI_LINK | 10.1016/j.jhep.2014.06.025 | ||
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