Diversity, ecology and intestinal function of bifidobacteria

Typeset version

 

TY  - JOUR
  - Francesca Bottacini1,2, Marco Ventura2 , Douwe van Sinderen1 , Mary O’Connell Motherway1*
  - 2014
  - September
  - Microbial Cell Factories
  - Diversity, ecology and intestinal function of bifidobacteria
  - In Press
  - ()
  - 13
  - The human gastrointestinal tract represents an environment which is a densely populated home for a microbiota that has evolved to positively contribute to host health. At birth the essentially sterile gastrointestinal tract (GIT) is rapidly colonized by microorganisms that originate from the mother and the surrounding environment. Within a short timeframe a microbiota establishes within the (breastfed) infant’s GIT where bifidobacteria are among the dominant members, although their numerical dominance disappears following weaning. The numerous health benefits associated with bifidobacteria, and the consequent commercial relevance resulting from their incorporation into functional foods, has led to intensified research aimed at the molecular understanding of claimed probiotic attributes of this genus. In this review we provide the current status on the diversity and ecology of bifidobacteria. In addition, we will discuss the molecular mechanisms that allow this intriguing group of bacteria to colonize and persist in the GIT, so as to facilitate interaction with its host.
DA  - 2014/09
ER  - 
@article{V279397715,
   = {Francesca Bottacini1, 2 and  Marco Ventura2 ,  Douwe van Sinderen1  and  Mary O’Connell Motherway1* },
   = {2014},
   = {September},
   = {Microbial Cell Factories},
   = {Diversity, ecology and intestinal function of bifidobacteria},
   = {In Press},
   = {()},
   = {13},
   = {{The human gastrointestinal tract represents an environment which is a densely populated home for a microbiota that has evolved to positively contribute to host health. At birth the essentially sterile gastrointestinal tract (GIT) is rapidly colonized by microorganisms that originate from the mother and the surrounding environment. Within a short timeframe a microbiota establishes within the (breastfed) infant’s GIT where bifidobacteria are among the dominant members, although their numerical dominance disappears following weaning. The numerous health benefits associated with bifidobacteria, and the consequent commercial relevance resulting from their incorporation into functional foods, has led to intensified research aimed at the molecular understanding of claimed probiotic attributes of this genus. In this review we provide the current status on the diversity and ecology of bifidobacteria. In addition, we will discuss the molecular mechanisms that allow this intriguing group of bacteria to colonize and persist in the GIT, so as to facilitate interaction with its host.}},
  source = {IRIS}
}
AUTHORSFrancesca Bottacini1,2, Marco Ventura2 , Douwe van Sinderen1 , Mary O’Connell Motherway1*
YEAR2014
MONTHSeptember
JOURNAL_CODEMicrobial Cell Factories
TITLEDiversity, ecology and intestinal function of bifidobacteria
STATUSIn Press
TIMES_CITED()
SEARCH_KEYWORD
VOLUME13
ISSUE
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END_PAGE
ABSTRACTThe human gastrointestinal tract represents an environment which is a densely populated home for a microbiota that has evolved to positively contribute to host health. At birth the essentially sterile gastrointestinal tract (GIT) is rapidly colonized by microorganisms that originate from the mother and the surrounding environment. Within a short timeframe a microbiota establishes within the (breastfed) infant’s GIT where bifidobacteria are among the dominant members, although their numerical dominance disappears following weaning. The numerous health benefits associated with bifidobacteria, and the consequent commercial relevance resulting from their incorporation into functional foods, has led to intensified research aimed at the molecular understanding of claimed probiotic attributes of this genus. In this review we provide the current status on the diversity and ecology of bifidobacteria. In addition, we will discuss the molecular mechanisms that allow this intriguing group of bacteria to colonize and persist in the GIT, so as to facilitate interaction with its host.
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