IRIS publication 43336889
The recombinant phage lysin LysK has a broad spectrum of lytic activity against clinically relevant Staphylococci, including methicillin-resistant Staphylococcus aureus
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TY - JOUR - O'Flaherty, S,Coffey, A,Meaney, W,Fitzgerald, GF,Ross, RP - 2005 - May - Journal of Bacteriology - The recombinant phage lysin LysK has a broad spectrum of lytic activity against clinically relevant Staphylococci, including methicillin-resistant Staphylococcus aureus - Validated - () - IDENTIFICATION ENDOLYSIN ENZYME AGENT HOLIN GENE - 187 - 7161 - 7164 - This study concerns the cloning, characterization, and expression of the lysin (LysK) from staphylococcal phage K in Lactococcus lactis. Lactococcal lysates containing recombinant LysK were found to inhibit a range of different species of staphylococci isolated from bovine and human infection sources, including methicillin-resistant Staphylococcus aureus. LysK thus has potential as an antimicrobial for applications in the prevention and/or treatment of infections caused by staphylococci. - DOI 10.1128/JB.187.20.7161-7164.2005 DA - 2005/05 ER -
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@article{V43336889, = {O'Flaherty, S and Coffey, A and Meaney, W and Fitzgerald, GF and Ross, RP }, = {2005}, = {May}, = {Journal of Bacteriology}, = {The recombinant phage lysin LysK has a broad spectrum of lytic activity against clinically relevant Staphylococci, including methicillin-resistant Staphylococcus aureus}, = {Validated}, = {()}, = {IDENTIFICATION ENDOLYSIN ENZYME AGENT HOLIN GENE}, = {187}, pages = {7161--7164}, = {{This study concerns the cloning, characterization, and expression of the lysin (LysK) from staphylococcal phage K in Lactococcus lactis. Lactococcal lysates containing recombinant LysK were found to inhibit a range of different species of staphylococci isolated from bovine and human infection sources, including methicillin-resistant Staphylococcus aureus. LysK thus has potential as an antimicrobial for applications in the prevention and/or treatment of infections caused by staphylococci.}}, = {DOI 10.1128/JB.187.20.7161-7164.2005}, source = {IRIS} }
Data as stored in IRIS
AUTHORS | O'Flaherty, S,Coffey, A,Meaney, W,Fitzgerald, GF,Ross, RP | ||
YEAR | 2005 | ||
MONTH | May | ||
JOURNAL_CODE | Journal of Bacteriology | ||
TITLE | The recombinant phage lysin LysK has a broad spectrum of lytic activity against clinically relevant Staphylococci, including methicillin-resistant Staphylococcus aureus | ||
STATUS | Validated | ||
TIMES_CITED | () | ||
SEARCH_KEYWORD | IDENTIFICATION ENDOLYSIN ENZYME AGENT HOLIN GENE | ||
VOLUME | 187 | ||
ISSUE | |||
START_PAGE | 7161 | ||
END_PAGE | 7164 | ||
ABSTRACT | This study concerns the cloning, characterization, and expression of the lysin (LysK) from staphylococcal phage K in Lactococcus lactis. Lactococcal lysates containing recombinant LysK were found to inhibit a range of different species of staphylococci isolated from bovine and human infection sources, including methicillin-resistant Staphylococcus aureus. LysK thus has potential as an antimicrobial for applications in the prevention and/or treatment of infections caused by staphylococci. | ||
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DOI_LINK | DOI 10.1128/JB.187.20.7161-7164.2005 | ||
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