Bioactivities of Glycoalkaloids and Their Aglycones from Solanum Species

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TY  - JOUR
  - Milner, Sinead Eileen and Brunton, Nigel Patrick and Jones, Peter Wyn and O'Brien, Nora Mary and Collins, Stuart Gerard and Maguire, Anita Rose
  - 2011
  - Journal of Agricultural and Food Chemistry
  - Bioactivities of Glycoalkaloids and Their Aglycones from Solanum Species
  - Validated
  - ()
  - 59
  - 8
  - 3454
  - 3484
  - Potatoes, tomatoes, and aubergines are all species of the Solanum genus and contain a vast array of secondary metabolites including calystegine alkaloids, phenolic compounds, lectins, and glycoalkaloids. Glycoalkaloids have been the subject of many literature papers, occur widely in the human diet, and are known to induce toxicity. Therefore, from a food safety perspective further information is required regarding their analysis, toxicity, and bioavailability. This is especially important in crop cultivars derived from wild species to prevent glycoalkaloid-induced toxicity. A comprehensive review of the bioactivity of glycoalkaloids and their aglycones of the Solanum species, particularly focused on comparison of their bioactivities including their anticancer, anticholesterol, antimicrobial, anti-inflammatory, antinociceptive, and antipyretic effects, toxicity, and synergism of action of the principal Solanum glycoalkaloids, correlated to differences of their individual molecular structures is presented.
DA  - 2011/NaN
ER  - 
@article{V113214870,
   = {Milner, Sinead Eileen and Brunton, Nigel Patrick and Jones, Peter Wyn and O'Brien, Nora Mary and Collins, Stuart Gerard and Maguire, Anita Rose},
   = {2011},
   = {Journal of Agricultural and Food Chemistry},
   = {Bioactivities of Glycoalkaloids and Their Aglycones from Solanum Species},
   = {Validated},
   = {()},
   = {59},
   = {8},
  pages = {3454--3484},
   = {{Potatoes, tomatoes, and aubergines are all species of the Solanum genus and contain a vast array of secondary metabolites including calystegine alkaloids, phenolic compounds, lectins, and glycoalkaloids. Glycoalkaloids have been the subject of many literature papers, occur widely in the human diet, and are known to induce toxicity. Therefore, from a food safety perspective further information is required regarding their analysis, toxicity, and bioavailability. This is especially important in crop cultivars derived from wild species to prevent glycoalkaloid-induced toxicity. A comprehensive review of the bioactivity of glycoalkaloids and their aglycones of the Solanum species, particularly focused on comparison of their bioactivities including their anticancer, anticholesterol, antimicrobial, anti-inflammatory, antinociceptive, and antipyretic effects, toxicity, and synergism of action of the principal Solanum glycoalkaloids, correlated to differences of their individual molecular structures is presented.}},
  source = {IRIS}
}
AUTHORSMilner, Sinead Eileen and Brunton, Nigel Patrick and Jones, Peter Wyn and O'Brien, Nora Mary and Collins, Stuart Gerard and Maguire, Anita Rose
YEAR2011
MONTH
JOURNAL_CODEJournal of Agricultural and Food Chemistry
TITLEBioactivities of Glycoalkaloids and Their Aglycones from Solanum Species
STATUSValidated
TIMES_CITED()
SEARCH_KEYWORD
VOLUME59
ISSUE8
START_PAGE3454
END_PAGE3484
ABSTRACTPotatoes, tomatoes, and aubergines are all species of the Solanum genus and contain a vast array of secondary metabolites including calystegine alkaloids, phenolic compounds, lectins, and glycoalkaloids. Glycoalkaloids have been the subject of many literature papers, occur widely in the human diet, and are known to induce toxicity. Therefore, from a food safety perspective further information is required regarding their analysis, toxicity, and bioavailability. This is especially important in crop cultivars derived from wild species to prevent glycoalkaloid-induced toxicity. A comprehensive review of the bioactivity of glycoalkaloids and their aglycones of the Solanum species, particularly focused on comparison of their bioactivities including their anticancer, anticholesterol, antimicrobial, anti-inflammatory, antinociceptive, and antipyretic effects, toxicity, and synergism of action of the principal Solanum glycoalkaloids, correlated to differences of their individual molecular structures is presented.
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