Synthesis of enantioenriched sulfoxides

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TY  - JOUR
  - O'Mahony, Graham E. and Kelly, Padraig and Lawrence, Simon E. and Maguire, Anita R.
  - 2011
  - Arkivoc
  - Synthesis of enantioenriched sulfoxides
  - Validated
  - ()
  - 1
  - 110
  - This review discusses strategies for the asymmetric synthesis of sulfoxides, compounds with many applications in stereoselective synthesis and in some cases with pharmaceutical application. The review describes asymmetric oxidation, including metal catalyzed and nonmetal and biological oxidation processes, in addition to synthetic approaches via nucleophilic substitution of appropriately substituted precursors. Kinetic resolution in oxidation of sulfoxides to the analogous sulfones is also discussed; in certain instances, access to enantioenriched sulfoxides can be achieved via a combination of asymmetric sulfide oxidation and complementary kinetic resolution in sulfoxide oxidation.
DA  - 2011/NaN
ER  - 
@article{V119669225,
   = {O'Mahony, Graham E. and Kelly, Padraig and Lawrence, Simon E. and Maguire, Anita R.},
   = {2011},
   = {Arkivoc},
   = {Synthesis of enantioenriched sulfoxides},
   = {Validated},
   = {()},
  pages = {1--110},
   = {{This review discusses strategies for the asymmetric synthesis of sulfoxides, compounds with many applications in stereoselective synthesis and in some cases with pharmaceutical application. The review describes asymmetric oxidation, including metal catalyzed and nonmetal and biological oxidation processes, in addition to synthetic approaches via nucleophilic substitution of appropriately substituted precursors. Kinetic resolution in oxidation of sulfoxides to the analogous sulfones is also discussed; in certain instances, access to enantioenriched sulfoxides can be achieved via a combination of asymmetric sulfide oxidation and complementary kinetic resolution in sulfoxide oxidation.}},
  source = {IRIS}
}
AUTHORSO'Mahony, Graham E. and Kelly, Padraig and Lawrence, Simon E. and Maguire, Anita R.
YEAR2011
MONTH
JOURNAL_CODEArkivoc
TITLESynthesis of enantioenriched sulfoxides
STATUSValidated
TIMES_CITED()
SEARCH_KEYWORD
VOLUME
ISSUE
START_PAGE1
END_PAGE110
ABSTRACTThis review discusses strategies for the asymmetric synthesis of sulfoxides, compounds with many applications in stereoselective synthesis and in some cases with pharmaceutical application. The review describes asymmetric oxidation, including metal catalyzed and nonmetal and biological oxidation processes, in addition to synthetic approaches via nucleophilic substitution of appropriately substituted precursors. Kinetic resolution in oxidation of sulfoxides to the analogous sulfones is also discussed; in certain instances, access to enantioenriched sulfoxides can be achieved via a combination of asymmetric sulfide oxidation and complementary kinetic resolution in sulfoxide oxidation.
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