A practical chemo-enzymatic approach to highly enantio-enriched cyanohydrin acetates

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TY  - JOUR
  - Maguire, NM,Ford, A,Clarke, SL,Eccles, KS,Lawrence, SE,Brossat, M,Moody, TS,Maguire, AR
  - 2011
  - January
  - Tetrahedron-Asymmetry
  - A practical chemo-enzymatic approach to highly enantio-enriched cyanohydrin acetates
  - Validated
  - ()
  - CATALYZED KINETIC RESOLUTION RACEMIC CYANOHYDRINS BUILDING-BLOCKS CANDIDA-RUGOSA LIPASE ESTERIFICATION ESTERS
  - 22
  - 2144
  - 2150
  - The preparation of enantiopure cyanohydrin acetates via enzymatic hydrolysis has been investigated by screening a range of biocatalysts and reaction conditions. Enzymatic resolution has been optimised through variation of the hydrolase biocatalyst and reaction conditions leading to synthetically useful routes to enantiopure cyanohydrin acetates. (C) 2011 Elsevier Ltd. All rights reserved.
  - DOI 10.1016/j.tetasy.2011.11.022
DA  - 2011/01
ER  - 
@article{V146554694,
   = {Maguire,  NM and Ford,  A and Clarke,  SL and Eccles,  KS and Lawrence,  SE and Brossat,  M and Moody,  TS and Maguire,  AR },
   = {2011},
   = {January},
   = {Tetrahedron-Asymmetry},
   = {A practical chemo-enzymatic approach to highly enantio-enriched cyanohydrin acetates},
   = {Validated},
   = {()},
   = {CATALYZED KINETIC RESOLUTION RACEMIC CYANOHYDRINS BUILDING-BLOCKS CANDIDA-RUGOSA LIPASE ESTERIFICATION ESTERS},
   = {22},
  pages = {2144--2150},
   = {{The preparation of enantiopure cyanohydrin acetates via enzymatic hydrolysis has been investigated by screening a range of biocatalysts and reaction conditions. Enzymatic resolution has been optimised through variation of the hydrolase biocatalyst and reaction conditions leading to synthetically useful routes to enantiopure cyanohydrin acetates. (C) 2011 Elsevier Ltd. All rights reserved.}},
   = {DOI 10.1016/j.tetasy.2011.11.022},
  source = {IRIS}
}
AUTHORSMaguire, NM,Ford, A,Clarke, SL,Eccles, KS,Lawrence, SE,Brossat, M,Moody, TS,Maguire, AR
YEAR2011
MONTHJanuary
JOURNAL_CODETetrahedron-Asymmetry
TITLEA practical chemo-enzymatic approach to highly enantio-enriched cyanohydrin acetates
STATUSValidated
TIMES_CITED()
SEARCH_KEYWORDCATALYZED KINETIC RESOLUTION RACEMIC CYANOHYDRINS BUILDING-BLOCKS CANDIDA-RUGOSA LIPASE ESTERIFICATION ESTERS
VOLUME22
ISSUE
START_PAGE2144
END_PAGE2150
ABSTRACTThe preparation of enantiopure cyanohydrin acetates via enzymatic hydrolysis has been investigated by screening a range of biocatalysts and reaction conditions. Enzymatic resolution has been optimised through variation of the hydrolase biocatalyst and reaction conditions leading to synthetically useful routes to enantiopure cyanohydrin acetates. (C) 2011 Elsevier Ltd. All rights reserved.
PUBLISHER_LOCATION
ISBN_ISSN
EDITION
URL
DOI_LINKDOI 10.1016/j.tetasy.2011.11.022
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