IRIS publication 146554694
A practical chemo-enzymatic approach to highly enantio-enriched cyanohydrin acetates
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TY - JOUR - Maguire, NM,Ford, A,Clarke, SL,Eccles, KS,Lawrence, SE,Brossat, M,Moody, TS,Maguire, AR - 2011 - January - Tetrahedron-Asymmetry - A practical chemo-enzymatic approach to highly enantio-enriched cyanohydrin acetates - Validated - () - CATALYZED KINETIC RESOLUTION RACEMIC CYANOHYDRINS BUILDING-BLOCKS CANDIDA-RUGOSA LIPASE ESTERIFICATION ESTERS - 22 - 2144 - 2150 - The preparation of enantiopure cyanohydrin acetates via enzymatic hydrolysis has been investigated by screening a range of biocatalysts and reaction conditions. Enzymatic resolution has been optimised through variation of the hydrolase biocatalyst and reaction conditions leading to synthetically useful routes to enantiopure cyanohydrin acetates. (C) 2011 Elsevier Ltd. All rights reserved. - DOI 10.1016/j.tetasy.2011.11.022 DA - 2011/01 ER -
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@article{V146554694, = {Maguire, NM and Ford, A and Clarke, SL and Eccles, KS and Lawrence, SE and Brossat, M and Moody, TS and Maguire, AR }, = {2011}, = {January}, = {Tetrahedron-Asymmetry}, = {A practical chemo-enzymatic approach to highly enantio-enriched cyanohydrin acetates}, = {Validated}, = {()}, = {CATALYZED KINETIC RESOLUTION RACEMIC CYANOHYDRINS BUILDING-BLOCKS CANDIDA-RUGOSA LIPASE ESTERIFICATION ESTERS}, = {22}, pages = {2144--2150}, = {{The preparation of enantiopure cyanohydrin acetates via enzymatic hydrolysis has been investigated by screening a range of biocatalysts and reaction conditions. Enzymatic resolution has been optimised through variation of the hydrolase biocatalyst and reaction conditions leading to synthetically useful routes to enantiopure cyanohydrin acetates. (C) 2011 Elsevier Ltd. All rights reserved.}}, = {DOI 10.1016/j.tetasy.2011.11.022}, source = {IRIS} }
Data as stored in IRIS
AUTHORS | Maguire, NM,Ford, A,Clarke, SL,Eccles, KS,Lawrence, SE,Brossat, M,Moody, TS,Maguire, AR | ||
YEAR | 2011 | ||
MONTH | January | ||
JOURNAL_CODE | Tetrahedron-Asymmetry | ||
TITLE | A practical chemo-enzymatic approach to highly enantio-enriched cyanohydrin acetates | ||
STATUS | Validated | ||
TIMES_CITED | () | ||
SEARCH_KEYWORD | CATALYZED KINETIC RESOLUTION RACEMIC CYANOHYDRINS BUILDING-BLOCKS CANDIDA-RUGOSA LIPASE ESTERIFICATION ESTERS | ||
VOLUME | 22 | ||
ISSUE | |||
START_PAGE | 2144 | ||
END_PAGE | 2150 | ||
ABSTRACT | The preparation of enantiopure cyanohydrin acetates via enzymatic hydrolysis has been investigated by screening a range of biocatalysts and reaction conditions. Enzymatic resolution has been optimised through variation of the hydrolase biocatalyst and reaction conditions leading to synthetically useful routes to enantiopure cyanohydrin acetates. (C) 2011 Elsevier Ltd. All rights reserved. | ||
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DOI_LINK | DOI 10.1016/j.tetasy.2011.11.022 | ||
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