Preparation of 2-Aminopyridoimidazoles and 2-Aminobenzimidazoles via Phosphorus Oxychloride-Mediated Cyclization of Aminoureas

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TY  - JOUR
  - Deasy, RE,Slattery, CN,Maguire, AR,Kjell, DP,Hawk, MKN,Joo, JM,Gu, RL,Moynihan, H
  - 2014
  - April
  - The Journal of Organic Chemistry
  - Preparation of 2-Aminopyridoimidazoles and 2-Aminobenzimidazoles via Phosphorus Oxychloride-Mediated Cyclization of Aminoureas
  - Validated
  - WOS: 5 ()
  - SPONGE LEUCETTA-CHAGOSENSIS IMIDAZOLE ALKALOIDS IN-VIVO 2-AMINOIMIDAZOLES DISPACAMIDES ANTAGONIST INHIBITOR
  - 79
  - 3688
  - 3695
  - The novel preparation of 2-aminopyridoimidazoles and 2-aminobenzimidazoles via the cyclization of (2-aminopyridin-3-yl)urea and (2-aminophenyl)urea substrates in the presence of phosphorus oxychloride is described. This methodology is demonstrated for a range of urea substrates with aminoimidazole products obtained in good yields and with excellent levels of purity.
  - 10.1021/jo500360k
DA  - 2014/04
ER  - 
@article{V271355206,
   = {Deasy,  RE and Slattery,  CN and Maguire,  AR and Kjell,  DP and Hawk,  MKN and Joo,  JM and Gu,  RL and Moynihan,  H },
   = {2014},
   = {April},
   = {The Journal of Organic Chemistry},
   = {Preparation of 2-Aminopyridoimidazoles and 2-Aminobenzimidazoles via Phosphorus Oxychloride-Mediated Cyclization of Aminoureas},
   = {Validated},
   = {WOS: 5 ()},
   = {SPONGE LEUCETTA-CHAGOSENSIS IMIDAZOLE ALKALOIDS IN-VIVO 2-AMINOIMIDAZOLES DISPACAMIDES ANTAGONIST INHIBITOR},
   = {79},
  pages = {3688--3695},
   = {{The novel preparation of 2-aminopyridoimidazoles and 2-aminobenzimidazoles via the cyclization of (2-aminopyridin-3-yl)urea and (2-aminophenyl)urea substrates in the presence of phosphorus oxychloride is described. This methodology is demonstrated for a range of urea substrates with aminoimidazole products obtained in good yields and with excellent levels of purity.}},
   = {10.1021/jo500360k},
  source = {IRIS}
}
AUTHORSDeasy, RE,Slattery, CN,Maguire, AR,Kjell, DP,Hawk, MKN,Joo, JM,Gu, RL,Moynihan, H
YEAR2014
MONTHApril
JOURNAL_CODEThe Journal of Organic Chemistry
TITLEPreparation of 2-Aminopyridoimidazoles and 2-Aminobenzimidazoles via Phosphorus Oxychloride-Mediated Cyclization of Aminoureas
STATUSValidated
TIMES_CITEDWOS: 5 ()
SEARCH_KEYWORDSPONGE LEUCETTA-CHAGOSENSIS IMIDAZOLE ALKALOIDS IN-VIVO 2-AMINOIMIDAZOLES DISPACAMIDES ANTAGONIST INHIBITOR
VOLUME79
ISSUE
START_PAGE3688
END_PAGE3695
ABSTRACTThe novel preparation of 2-aminopyridoimidazoles and 2-aminobenzimidazoles via the cyclization of (2-aminopyridin-3-yl)urea and (2-aminophenyl)urea substrates in the presence of phosphorus oxychloride is described. This methodology is demonstrated for a range of urea substrates with aminoimidazole products obtained in good yields and with excellent levels of purity.
PUBLISHER_LOCATION
ISBN_ISSN
EDITION
URL
DOI_LINK10.1021/jo500360k
FUNDING_BODY
GRANT_DETAILS