TY  - JOUR
  - McCarthy, FO,Chopra, J,Ford, A,Hogan, SA,Kerry, JP,O'Brien, NM,Ryan, E,Maguire, AR
  - 2005
  - May
  - Organic and Biomolecular Chemistry
  - Synthesis, isolation and characterisation of beta-sitosterol and beta-sitosterol oxide derivatives
  - Validated
  - ()
  - OXIDATION-PRODUCTS CHROMATOGRAPHIC SEPARATION MASS-SPECTROMETRY STEROL SYNTHESIS HIGHER-PLANTS PHYTOSTEROLS CHOLESTEROL RATS OXYPHYTOSTEROLS ATHEROSCLEROSIS
  - 3
  - 3059
  - 3065
  - beta-Sitosterol is the most prevalent plant cholesterol derivative (phytosterol) and can undergo similar oxidation to cholesterol, leading to beta-sitosterol oxides. The biological impact of phytosterol oxides has only been evaluated in a phytosterol blend (usually of beta-sitosterol, campesterol, stigmasterol and dihydrobrassicasterol). The lack of pure phytosterols, including beta-sitosterol, hinders the collection of significant toxicity data on the individual beta-sitosterol oxides. An efficient synthetic route to multi-gram quantities of pure beta-sitosterol is described here, together with the first syntheses and characterisation of pure beta-sitosterol oxides.
  - DOI 10.1093/b505069c
DA  - 2005/05
ER  - 

@article{V43337012,
   = {McCarthy,  FO and Chopra,  J and Ford,  A and Hogan,  SA and Kerry,  JP and O'Brien,  NM and Ryan,  E and Maguire,  AR },
   = {2005},
   = {May},
   = {Organic and Biomolecular Chemistry},
   = {Synthesis, isolation and characterisation of beta-sitosterol and beta-sitosterol oxide derivatives},
   = {Validated},
   = {()},
   = {OXIDATION-PRODUCTS CHROMATOGRAPHIC SEPARATION MASS-SPECTROMETRY STEROL SYNTHESIS HIGHER-PLANTS PHYTOSTEROLS CHOLESTEROL RATS OXYPHYTOSTEROLS ATHEROSCLEROSIS},
   = {3},
  pages = {3059--3065},
   = {{beta-Sitosterol is the most prevalent plant cholesterol derivative (phytosterol) and can undergo similar oxidation to cholesterol, leading to beta-sitosterol oxides. The biological impact of phytosterol oxides has only been evaluated in a phytosterol blend (usually of beta-sitosterol, campesterol, stigmasterol and dihydrobrassicasterol). The lack of pure phytosterols, including beta-sitosterol, hinders the collection of significant toxicity data on the individual beta-sitosterol oxides. An efficient synthetic route to multi-gram quantities of pure beta-sitosterol is described here, together with the first syntheses and characterisation of pure beta-sitosterol oxides.}},
   = {DOI 10.1093/b505069c},
  source = {IRIS}
}