Professor & Chair
Anatomy & Neuroscience
386
Western Gateway Building
University College Cork
Cork
Ireland

T: +353-21-420-5426
E: J.Cryan@ucc.ie

John F. Cryan is Professor & Chair, Dept. of Anatomy & Neuroscience, University College Cork.  He received a B.Sc. (Hons) and PhD from the National University of Ireland, Galway, Ireland. He was a visiting fellow at the Dept Psychiatry, University of Melbourne, Australia (1997-1998), which was followed by postdoctoral fellowships  at the University of Pennsylvania, Philadelphia, USA and The Scripps Research Institute, La Jolla, California. He spent four years at the Novartis Institutes for BioMedical Research in Basel Switzerland, as a LabHead, Behavioural Pharmacology prior to joining UCC in 2005 where he was  a Senior Lecturer in Pharmacology in the School of Pharmacy and in the Dept. Pharmacology & Therapeutics UCC. Currently he is also a Principal Investigator in the Alimentary Pharmabiotic Centre (http://www.ucc.ie/research/apc/content).

Prof. Cryan has an H-Index of 45 (Google Scholar) having published over 190 peer-reviewed articles and book chapters including articles in high-impact journals such as PNAS, Neuron, Nature Reviews Neurosci. Molecular Psychiatry, Biological Psychiatry, Progress in Neurobiology, Nature Reviews Drug Discovery, Gastroenterology, Gut and Journal of Neuroscience. He  has edited books  on "Behavioural Neurogenetics" (Springer Press, 2012) and on "Depression: From Psychopathology to Pharmacotherapy" (Karger Press, 2010).

Prof. Cryan is a Senior Editor of Neuropharmacology and Nutritional Neuroscience and an Editor of British Journal of Pharmacology. He is Advisory Editor of Psychopharmacology; on the Board of Reviewing Editors of Brain Research; an Associate Editor of Frontiers in Behavioural Neuroscience; an Associate Editor of Frontiers in Psychopharmacology and Frontiers in Gastrointestinal Pharmacology; an Editorial Board Member of Behavioural Pharmacology; Neuroscience and Biobehavioral Reviews and International Journal of Neuropsychopharmacology. He is an adhoc reviewer for >75  different journals including Science, PNAS, J.Neurosci, Mol. Psychiatry, Arch Gen Psych, TiPS, Nature Methods and  PLOS Biology. Prof Cryan received the inaugural University College Cork Researcher of the Year Award in 2012. Cryan has also been honoured with the European College of Neuropsychopharmacology (ECNP) Fellowship Award, the Wyeth Psychopharmacology Award from British Association of Psychopharmacology and the Young Scientist Award from the European Behavioural Pharmacology Society. He has received commercialisation awards from UCC in 2012 and 2013. In 2013 he received the University of Utrecht Award for Excellence in Pharmaceutical Research and delivered the Royal Academy of Medicine in Ireland Conway Review Lecture.

Prof. Cryan's current research interests include the neurobiological basis of stress-related neuropsychiatric disorders including depression, anxiety and drug dependence. Moreover, his group is also focused on understanding the interaction between brain, gut & microbiome and how it applies to stress and immune-related disorders, including irritable bowel syndrome and obesity and neurodevelopmental disorders such as autism. He is also interested in applying novel approaches to facilitate drug/siRNA delivery to the brain in vivo.

Prof. Cryan's research group consists of 7 Postdoctoral Fellows, 13 PhD students, 2 MD students, 1 MSc Students, 3 research scientists and various visiting students from Ireland, Spain, The Netherlands, USA & Canada. It is funded by Science Foundation Ireland, the Health Research Board, Enterprise Ireland and the Irish Research Council. Moreover, Prof. Cryan receives funding as a PI on the two different EU Framework 7 Programme grants.

Books

 YearPublication
(2012)Behavioural Neurogenetics.
Cryan (2012) Behavioural Neurogenetics. Heidelberg: Springer. [Details]
(2010)Depression: From Psychopathology to Pharmacotherapy.
Cryan, JF and Leonard, BE; (2010) Depression: From Psychopathology to Pharmacotherapy. Basel: Karger. [Details]

Book Chapters

 YearPublication
(2009)'The tail suspension test: A model for characterizing antidepressant activity in mice'
O'Leary OF, Cryan JF; (2009) 'The tail suspension test: A model for characterizing antidepressant activity in mice' In: Todd Gould (eds). Mood & Anxiety Related Phenotypes in Mice; Neuromethods. USA: Springer. [No details]
(2010)'The behavioural Genetics of serotonin: relevance to anxiety and depression'
O'Leary OF, Cryan JF ; (2010) 'The behavioural Genetics of serotonin: relevance to anxiety and depression' In: Christian P. Muller & Barry L. Jacobs (eds). Handbook of the Behavioral Neurobiology of Serotonin. USA: Academic Press. [No details]
(2008)'GABA receptors and depression: Focus on GABAB'
Cryan JF, Slattery DA; (2008) 'GABA receptors and depression: Focus on GABAB' In: Chaki S and Shirayama Y (eds). Recent Developments on Depression Research. to follow: to follow. [No details]
(2008)'Developing more efficacious antidepressant medications: Improving and aligning preclinical and clinical assessment tools'
Cryan JF, Sanchez C, Dinan TG, Borsini F; (2008) 'Developing more efficacious antidepressant medications: Improving and aligning preclinical and clinical assessment tools' In: RA McArthur and F Borsini (eds). Animal and Translational Models for Drug Discovery: Psychiatric Disorders. NY: Elsevier. [No details]
(2007)'Role of glutamate in anxiety'
Cryan JF, Dev KK; (2007) 'Role of glutamate in anxiety' In: Blanchard DC, Blanchard RM (eds). Handbook of fear and anxiety. to follow: to follow. [No details]
(2006)'Modelling human anxiety and depression in mutant mice'
Holmes A, Cryan JF; (2006) 'Modelling human anxiety and depression in mutant mice' In: G Fisch and J Flint (eds). Transgenic and Knockout Models of Neuropsychiatric Disorders. to follow: Humana Press. [No details]

Peer Reviewed Journals

 YearPublication
(2012)'Interleukin-6 modulates transepithelial ion transport in Wistar Kyoto rat distal colon'
O’Malley D, Dinan TG & Cryan JF (2012) 'Interleukin-6 modulates transepithelial ion transport in Wistar Kyoto rat distal colon' [Details]
(2012)'Characterisation of cationic amphiphilic cyclodextrins for neuronal delivery of siRNA: Effect of reversing primary and secondary face modifications'
O'Mahony AM, Doyle D, Darcy R, Cryan JF, O'Driscoll CM. (2012) 'Characterisation of cationic amphiphilic cyclodextrins for neuronal delivery of siRNA: Effect of reversing primary and secondary face modifications' [DOI] [Full Text] [Details]
(2012)'Click-modified cyclodextrins as non-viral vectors for neuronal siRNA delivery'
O'Mahony, AM, Godinho, BMDC, Ogier, J, Devocelle, M, Darcy, R, Cryan, JF, O'Driscoll, CM (2012) 'Click-modified cyclodextrins as non-viral vectors for neuronal siRNA delivery' [DOI] [Full Text] [Details]
(2012)'DIFFERENTIAL LIPOPOLYSACCHARIDE-INDUCED IMMUNE ALTERATIONS IN THE HIPPOCAMPUS OF TWO MOUSE STRAINS: EFFECTS OF STRESS'
Browne, CA,O'Brien, FE,Connor, TJ,Dinan, TG,Cryan, JF (2012) 'DIFFERENTIAL LIPOPOLYSACCHARIDE-INDUCED IMMUNE ALTERATIONS IN THE HIPPOCAMPUS OF TWO MOUSE STRAINS: EFFECTS OF STRESS' [DOI] [Details]
(2012)'Bifidobacterium breve with alpha-Linolenic Acid and Linoleic Acid Alters Fatty Acid Metabolism in the Maternal Separation Model of Irritable Bowel Syndrome'
Barrett, E,Fitzgerald, P,Dinan, TG,Cryan, JF,Ross, RP,Quigley, EM,Shanahan, F,Kiely, B,Fitzgerald, GF,O'Toole, PW,Stanton, C (2012) 'Bifidobacterium breve with alpha-Linolenic Acid and Linoleic Acid Alters Fatty Acid Metabolism in the Maternal Separation Model of Irritable Bowel Syndrome' [DOI] [Details]
(2012)'Blockade of the GABA(B) receptor increases neurogenesis in the ventral but not dorsal adult hippocampus: Relevance to antidepressant action'
Felice, D,O'Leary, OF,Pizzo, RC,Cryan, JF (2012) 'Blockade of the GABA(B) receptor increases neurogenesis in the ventral but not dorsal adult hippocampus: Relevance to antidepressant action' [DOI] [Details]
(2012)'Click-Modified Cyclodextrins as Nonviral Vectors for Neuronal siRNA Delivery'
O'Mahony, AM,Godinho, BMDC,Ogier, J,Devocelle, M,Darcy, R,Cryan, JF,O'Driscoll, CM (2012) 'Click-Modified Cyclodextrins as Nonviral Vectors for Neuronal siRNA Delivery' [DOI] [Details]
(2012)'Genetic vs. pharmacological inactivation of COMT influences cannabinoid-induced expression of schizophrenia-related phenotypes'
O'Tuathaigh, CMP,Clarke, G,Walsh, J,Desbonnet, L,Petit, E,O'Leary, C,Tighe, O,Clarke, N,Karayiorgou, M,Gogos, JA,Dinan, TG,Cryan, JF,Waddington, JL (2012) 'Genetic vs. pharmacological inactivation of COMT influences cannabinoid-induced expression of schizophrenia-related phenotypes' [DOI] [Details]
(2012)'Schizophrenia patients with a history of childhood trauma have a pro-inflammatory phenotype'
Dennison, U,McKernan, D,Cryan, J,Dinan, T (2012) 'Schizophrenia patients with a history of childhood trauma have a pro-inflammatory phenotype' [DOI] [Details]
(2013)'In vitro investigations of the efficacy of Cyclodextrin-siRNA complexes modified with Lipid-PEG-Octaarginine: Towards A Formulation Strategy for Effective Neuronal siRNA Delivery'
O'Mahony, AM., Desgranges S., Ogier JR., Quinlan A., Devocelle M., Darcy, R., Cryan, JF and O'Driscoll, CM. (2013) 'In vitro investigations of the efficacy of Cyclodextrin-siRNA complexes modified with Lipid-PEG-Octaarginine: Towards A Formulation Strategy for Effective Neuronal siRNA Delivery' [DOI] [Full Text] [Details]
(2013)'Self-assembling Modified β-Cyclodextrin Nanoparticles as Neuronal siRNA Delivery Vectors: Focus on Huntington's Disease'
Godinho BM, Ogier JR, Darcy R, O'Driscoll CM, Cryan JF. (2013) 'Self-assembling Modified β-Cyclodextrin Nanoparticles as Neuronal siRNA Delivery Vectors: Focus on Huntington's Disease' [DOI] [Details]
(2013)'Cyclodextrins for Non-Viral Gene and siRNA Delivery'
O'Mahony AM., O’Neill MJ., Godinho BMDC., Darcy, R., Cryan, JF and; O'Driscoll, CM. (2013) 'Cyclodextrins for Non-Viral Gene and siRNA Delivery' [Full Text] [Details]
(2013)'Towards translational rodent models of depression'
O'Leary OF, Cryan JF (2013) 'Towards translational rodent models of depression' [Details]
(2010)'A Gut Feeling about GABA: Focus on GABA(B) Receptors'
Hyland NP and Cryan JF (2010) 'A Gut Feeling about GABA: Focus on GABA(B) Receptors' [DOI] [Details]
(2011)'Enhanced peripheral toll-like receptor responses in psychosis: further evidence of a pro-inflammatory phenotype'
McKernan, DP,Dennison, U,Gaszner, G,Cryan, JF,Dinan, TG (2011) 'Enhanced peripheral toll-like receptor responses in psychosis: further evidence of a pro-inflammatory phenotype' [DOI] [Details]
(2011)'BDNF expression in the hippocampus of maternally separated rats: does Bifidobacterium breve 6330 alter BDNF levels?'
O'Sullivan, E,Barrett, E,Grenham, S,Fitzgerald, P,Stanton, C,Ross, RP,Quigley, EMM,Cryan, JF,Dinan, TG (2011) 'BDNF expression in the hippocampus of maternally separated rats: does Bifidobacterium breve 6330 alter BDNF levels?' [DOI] [Details]
(2012)'A click chemistry route to 2-functionalised PEGylated and cationic beta-cyclodextrins: co-formulation opportunities for siRNA delivery'
O'Mahony, AM,Ogier, J,Desgranges, S,Cryan, JF,Darcy, R,O'Driscoll, CM (2012) 'A click chemistry route to 2-functionalised PEGylated and cationic beta-cyclodextrins: co-formulation opportunities for siRNA delivery' [DOI] [Full Text] [Details]
(2012)'Inhibition of P-glycoprotein enhances transport of imipramine across the blood-brain barrier: microdialysis studies in conscious freely moving rats'
O'Brien, FE,Clarke, G,Fitzgerald, P,Dinan, TG,Griffin, BT,Cryan, JF (2012) 'Inhibition of P-glycoprotein enhances transport of imipramine across the blood-brain barrier: microdialysis studies in conscious freely moving rats' [DOI] [Details]
(2012)'Using the rat forced swim test to assess antidepressant-like activity in rodents'
Slattery, DA,Cryan, JF (2012) 'Using the rat forced swim test to assess antidepressant-like activity in rodents' [DOI] [Details]
(2012)'Rodent models of colorectal distension'
O'Mahony SM, Tramullas M, Fitzgerald P, Cryan JF (2012) 'Rodent models of colorectal distension' [DOI] [Details]
(2012)'Dynamic 5-HT2C Receptor Editing in a Mouse Model of Obesity'
Schellekens, H,Clarke, G,Jeffery, IB,Dinan, TG,Cryan, JF (2012) 'Dynamic 5-HT2C Receptor Editing in a Mouse Model of Obesity' [DOI] [Details]
(2012)'The temporal impact of chronic intermittent psychosocial stress on high-fat diet-induced alterations in body weight'
Finger, BC,Dinan, TG,Cryan, JF (2012) 'The temporal impact of chronic intermittent psychosocial stress on high-fat diet-induced alterations in body weight' [DOI] [Details]
(2012)'Chronic stress-induced alterations in mouse colonic 5-HT and defecation responses are strain dependent'
Julio-Pieper, M,O'Mahony, CM,Clarke, G,Bravo, JA,Dinan, TG,Cryan, JF (2012) 'Chronic stress-induced alterations in mouse colonic 5-HT and defecation responses are strain dependent' [DOI] [Details]
(2012)'Lithium-induced effects on adult hippocampal neurogenesis are topographically segregated along the dorso-ventral axis of stressed mice'
O'Leary, OF,O'Connor, RM,Cryan, JF (2012) 'Lithium-induced effects on adult hippocampal neurogenesis are topographically segregated along the dorso-ventral axis of stressed mice' [DOI] [Details]
(2012)'Diet-induced obesity blunts the behavioural effects of ghrelin: studies in a mouse-progressive ratio task'
Finger, BC,Dinan, TG,Cryan, JF (2012) 'Diet-induced obesity blunts the behavioural effects of ghrelin: studies in a mouse-progressive ratio task' [DOI] [Details]
(2012)'Blockade of the GABA(B) receptor increases neurogenesis in the ventral but not dorsal adult hippocampus: Relevance to antidepressant action'
Felice D, O'Leary OF, Pizzo RC, Cryan JF. (2012) 'Blockade of the GABA(B) receptor increases neurogenesis in the ventral but not dorsal adult hippocampus: Relevance to antidepressant action' [DOI] [Details]
(2013)'Hippocampal group III mGlu receptor mRNA levels are not altered in specific mouse models of stress, depression and antidepressant action'
O'Connor RM, Pusceddu M, O'Leary OF, Savignac HM, Bravo JF, El Yacoubi M, Vaugeois JM, Dinan TG, Cryan JF. (2013) 'Hippocampal group III mGlu receptor mRNA levels are not altered in specific mouse models of stress, depression and antidepressant action' [DOI] [Details]
(2013)'Lithium Augmentation of the effects of Desipramine in a Mouse Model of Treatment-Resistant Depression: A Role for Hippocampal Cell Proliferation'
O'Leary OF, Zandy S, Dinan TG, Cryan JF (2013) 'Lithium Augmentation of the effects of Desipramine in a Mouse Model of Treatment-Resistant Depression: A Role for Hippocampal Cell Proliferation' [DOI] [Details]
(2013)'Alterations in prefrontal cortical serotonin and antidepressant-like behavior in a novel C3H/HeJxDBA/2J recombinant inbred mouse strain'
Browne, CA,Clarke, G,Hanke, J,Dinan, TG,Schwegler, H,Yilmazer-Hanke, DM,Cryan, JF (2013) 'Alterations in prefrontal cortical serotonin and antidepressant-like behavior in a novel C3H/HeJxDBA/2J recombinant inbred mouse strain' [DOI] [Details]
(2004)'Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors'
Cryan JF, O'Leary OF, Jin SH, Friedland JC, Ouyang M, Hirsch BR, Page ME, Dalvi A, Thomas SA, Lucki I; (2004) 'Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors' [DOI] [Details]
(2010)'A Gut Feeling about GABA: Focus on GABA(B) Receptors'
Hyland NP, Cryan JF (2010) 'A Gut Feeling about GABA: Focus on GABA(B) Receptors' [DOI] [Details]
(2011)'Altered expression and secretion of colonic Interleukin-6 in a stress-sensitive animal model of brain-gut axis dysfunction'
O'Malley, D,Dinan, TG,Cryan, JF; (2011) 'Altered expression and secretion of colonic Interleukin-6 in a stress-sensitive animal model of brain-gut axis dysfunction' [DOI] [Details]
(2012)'Lithium-induced effects on adult hippocampal neurogenesis are topographically segregated along the dorso-ventral axis of stressed mice'
O'Leary OF, O'Connor RM, Cryan JF; (2012) 'Lithium-induced effects on adult hippocampal neurogenesis are topographically segregated along the dorso-ventral axis of stressed mice' [DOI] [Details]
(2011)'Genetic vs. pharmacological inactivation of COMT influences cannabinoid-induced expression of schizophrenia-related phenotypes'
O'Tuathaigh CM, Clarke G, Walsh J, Desbonnet L, Petit E, O'Leary C, Tighe O, Clarke N, Karayiorgou M, Gogos JA, Dinan TG, Cryan JF, Waddington JL (2011) 'Genetic vs. pharmacological inactivation of COMT influences cannabinoid-induced expression of schizophrenia-related phenotypes' [DOI] [Details]
(2011)'BDNF expression in the hippocampus of maternally separated rats: does Bifidobacterium breve 6330 alter BDNF levels?'
O'Sullivan E, Barrett E, Grenham S, Fitzgerald P, Stanton C, Ross RP, Quigley EM, Cryan JF, Dinan TG (2011) 'BDNF expression in the hippocampus of maternally separated rats: does Bifidobacterium breve 6330 alter BDNF levels?' [DOI] [Details]
(2011)'Do interactions between stress and immune responses lead to symptom exacerbations in irritable bowel syndrome?'
O'Malley D, Quigley EM, Dinan TG, Cryan JF (2011) 'Do interactions between stress and immune responses lead to symptom exacerbations in irritable bowel syndrome?' [DOI] [Details]
(2011)'Behavioral satiety sequence in a genetic mouse model of obesity: effects of ghrelin receptor ligands'
Finger, BC,Dinan, TG,Cryan, JF; (2011) 'Behavioral satiety sequence in a genetic mouse model of obesity: effects of ghrelin receptor ligands' [DOI] [Details]
(2011)'Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve'
Bravo, JA,Forsythe, P,Chew, MV,Escaravage, E,Savignac, HM,Dinan, TG,Bienenstock, J,Cryan, JF; (2011) 'Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve' [DOI] [Details]
(2011)'The effects of gabapentin in two animal models of co-morbid anxiety and visceral hypersensitivity'
O'Mahony, SM,Coelho, AM,Fitzgerald, P,Lee, K,Winchester, W,Dinan, TG,Cryan, JF; (2011) 'The effects of gabapentin in two animal models of co-morbid anxiety and visceral hypersensitivity' [DOI] [Details]
(2011)'HIGH-FAT DIET SELECTIVELY PROTECTS AGAINST THE EFFECTS OF CHRONIC SOCIAL STRESS IN THE MOUSE'
Finger, BC,Dinan, TG,Cryan, JF (2011) 'HIGH-FAT DIET SELECTIVELY PROTECTS AGAINST THE EFFECTS OF CHRONIC SOCIAL STRESS IN THE MOUSE' [DOI] [Details]
(2011)'Brain-gut-microbe communication in health and disease'
Grenham S, Clarke G, Cryan JF, Dinan TG (2011) 'Brain-gut-microbe communication in health and disease' [DOI] [Details]
(2011)'Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve'
Bravo JA, Forsythe P, Chew MV, Escaravage E, Savignac HM, Dinan TG, Bienenstock J, Cryan JF (2011) 'Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve' [DOI] [Details]
(2011)'High-fat diet selectively protects against the effects of chronic social stress in the mouse'
Finger BC, Dinan TG, Cryan JF (2011) 'High-fat diet selectively protects against the effects of chronic social stress in the mouse' [DOI] [Details]
(2011)'The effects of gabapentin in two animal models of co-morbid anxiety and visceral hypersensitivity'
O' Mahony SM, Coelho AM, Fitzgerald P, Lee K, Winchester W, Dinan TG, Cryan JF (2011) 'The effects of gabapentin in two animal models of co-morbid anxiety and visceral hypersensitivity' [DOI] [Details]
(2011)'The age of anxiety: role of animal models of anxiolytic action in drug discovery'
Cryan JF, Sweeney FF (2011) 'The age of anxiety: role of animal models of anxiolytic action in drug discovery' [DOI] [Details]
(2011)'Resistance to early-life stress in mice: effects of genetic background and stress duration'
Savignac HM, Dinan TG, Cryan JF (2011) 'Resistance to early-life stress in mice: effects of genetic background and stress duration' [DOI] [Details]
(2011)'Altered peripheral toll-like receptor responses in the irritable bowel syndrome'
McKernan DP, Gaszner G, Quigley EM, Cryan JF, Dinan TG (2011) 'Altered peripheral toll-like receptor responses in the irritable bowel syndrome' [DOI] [Details]
(2011)'Gut Memories: Towards a Cognitive Neurobiology of Irritable Bowel Syndrome'
Kennedy, P.J., G. Clarke, G., Quigley, E.M.M., Groeger., J.A., Dinan., T.G., Cryan. J.F. ; (2011) 'Gut Memories: Towards a Cognitive Neurobiology of Irritable Bowel Syndrome' [Details]
(2011)'Altered expression and secretion of colonic interleukin-6 in a stress-sensitive animal model of brain-gut axis dysfunction'
O'Malley D, Dinan TG, Cryan JF (2011) 'Altered expression and secretion of colonic interleukin-6 in a stress-sensitive animal model of brain-gut axis dysfunction' [DOI] [Details]
(2011)'Chronic psychosocial stress induces visceral hyperalgesia in mice'
Tramullas M, Dinan TG, Cryan JF (2011) 'Chronic psychosocial stress induces visceral hyperalgesia in mice' [DOI] [Details]
(2011)'Increased sensitivity to the effects of chronic social defeat stress in an innately anxious mouse strain'
Savignac HM, Finger BC, Pizzo RC, O'Leary OF, Dinan TG, Cryan JF; (2011) 'Increased sensitivity to the effects of chronic social defeat stress in an innately anxious mouse strain' [DOI] [Details]
(2012)'Chronic stress-induced alterations in mouse colonic 5-HT and defecation responses are strain dependent'
Julio-Pieper M, O'Mahony CM, Clarke G, Bravo JA, Dinan TG, Cryan JF (2012) 'Chronic stress-induced alterations in mouse colonic 5-HT and defecation responses are strain dependent' [DOI] [Details]
(2012)'Gut memories: towards a cognitive neurobiology of irritable bowel syndrome'
Kennedy PJ, Clarke G, Quigley EM, Groeger JA, Dinan TG, Cryan JF (2012) 'Gut memories: towards a cognitive neurobiology of irritable bowel syndrome' [DOI] [Details]
(2012)'Dynamic 5-HT(2C) Receptor Editing in a Mouse Model of Obesity'
Schellekens H, Clarke G, Jeffery IB, Dinan TG, Cryan JF (2012) 'Dynamic 5-HT(2C) Receptor Editing in a Mouse Model of Obesity' [DOI] [Full Text] [Details]
(2012)'Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk gene neuregulin-1: A putative model of gene×environment interaction'
Desbonnet L, O'Tuathaigh C, Clarke G, O'Leary C, Petit E, Clarke N, Tighe O, Lai D, Harvey R, Cryan JF, Dinan TG, Waddington JL (2012) 'Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk gene neuregulin-1: A putative model of gene×environment interaction' [Details]
(2012)'Schizophrenia patients with a history of childhood trauma have a pro-inflammatory phenotype'
Dennison U, McKernan D, Cryan J, Dinan T (2012) 'Schizophrenia patients with a history of childhood trauma have a pro-inflammatory phenotype' [DOI] [Details]
(2012)'Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters'
Davey KJ, O'Mahony SM, Schellekens H, O'Sullivan O, Bienenstock J, Cotter PD, Dinan TG, Cryan JF (2012) 'Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters' [DOI] [Details]
(2012)'Diet-induced obesity blunts the behavioural effects of ghrelin: studies in a mouse-progressive ratio task'
Finger BC, Dinan TG, Cryan JF (2012) 'Diet-induced obesity blunts the behavioural effects of ghrelin: studies in a mouse-progressive ratio task' [DOI] [Details]
(2012)'A Distinct Profile of Tryptophan Metabolism along the Kynurenine Pathway Downstream of Toll-Like Receptor Activation in Irritable Bowel Syndrome'
Clarke, G; McKernan, D; Gaszner, G; Quigley, E; Cryan, J; Dinan, T (2012) 'A Distinct Profile of Tryptophan Metabolism along the Kynurenine Pathway Downstream of Toll-Like Receptor Activation in Irritable Bowel Syndrome' [DOI] [Details]
(2013)'The Microbiome-Gut-Brain Axis During Early-Life Regulates the Hippocampal Serotonergic System in a Sex-Dependent Manner'
Clarke, G; Grenham, S; Scully, P; Fitzgerald, P; Moloney, R; Shanahan, F; Dinan, T; Cryan, J (2013) 'The Microbiome-Gut-Brain Axis During Early-Life Regulates the Hippocampal Serotonergic System in a Sex-Dependent Manner' [Details]
(2012)'Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk gene neuregulin-1: A putative model of gene x environment interaction'
Desbonnet, L,O'Tuathaigh, C,Clarke, G,O'Leary, C,Petit, E,Clarke, N,Tighe, O,Lai, D,Harvey, R,Cryan, JF,Dinan, TG,Waddington, JL (2012) 'Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk gene neuregulin-1: A putative model of gene x environment interaction' [DOI] [Details]
(2012)'Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters'
Davey, KJ,O'Mahony, SM,Schellekens, H,O'Sullivan, O,Bienenstock, J,Cotter, PD,Dinan, TG,Cryan, JF (2012) 'Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters' [DOI] [Details]
(2012)'Genetic Strain Differences in Learned Fear Inhibition Associated with Variation in Neuroendocrine, Autonomic, and Amygdala Dendritic Phenotypes'
Camp, MC,MacPherson, KP,Lederle, L,Graybeal, C,Gaburro, S,DeBrouse, LM,Ihne, JL,Bravo, JA,O'Connor, RM,Ciocchi, S,Wellman, CL,Luthi, A,Cryan, JF,Singewald, N,Holmes, A (2012) 'Genetic Strain Differences in Learned Fear Inhibition Associated with Variation in Neuroendocrine, Autonomic, and Amygdala Dendritic Phenotypes' [DOI] [Details]
(2012)'Chronic psychosocial stress induces visceral hyperalgesia in mice'
Tramullas, M,Dinan, TG,Cryan, JF (2012) 'Chronic psychosocial stress induces visceral hyperalgesia in mice' [DOI] [Details]
(2012)'Early-life stress induces visceral hypersensitivity in mice'
Moloney, RD,O'Leary, OF,Felice, D,Bettler, B,Dinan, TG,Cryan, JF (2012) 'Early-life stress induces visceral hypersensitivity in mice' [DOI] [Details]
(2012)'An effective dietary method for chronic tryptophan depletion in two mouse strains illuminates a role for 5-HT in nesting behaviour'
Browne, CA,Clarke, G,Dinan, TG,Cryan, JF (2012) 'An effective dietary method for chronic tryptophan depletion in two mouse strains illuminates a role for 5-HT in nesting behaviour' [DOI] [Details]
(2012)'Menstrual Cycle Influences Toll-Like Receptor Responses'
Dennison, U,McKernan, DP,Scully, P,Clarke, G,Cryan, J,Dinan, T (2012) 'Menstrual Cycle Influences Toll-Like Receptor Responses' [DOI] [Details]
(2012)'The temporal impact of chronic intermittent psychosocial stress on high-fat diet-induced alterations in body weight'
Finger BC, Dinan TG, Cryan JF (2012) 'The temporal impact of chronic intermittent psychosocial stress on high-fat diet-induced alterations in body weight' [DOI] [Details]
(2012)'Little things on which happiness depends: microRNAs as novel therapeutic targets for the treatment of anxiety and depression'
O'Connor RM, Dinan TG, Cryan JF (2012) 'Little things on which happiness depends: microRNAs as novel therapeutic targets for the treatment of anxiety and depression' [DOI] [Details]
(2012)'Early-life stress induces visceral hypersensitivity in mice'
Moloney RD, O'Leary OF, Felice D, Bettler B, Dinan TG, Cryan JF (2012) 'Early-life stress induces visceral hypersensitivity in mice' [DOI] [Details]
(2012)'Regulation of the stress response by the gut microbiota: Implications for psychoneuroendocrinology'
Dinan TG, Cryan JF (2012) 'Regulation of the stress response by the gut microbiota: Implications for psychoneuroendocrinology' [DOI] [Details]
(2012)'Early-life stress induces visceral hypersensitivity in mice'
Moloney RD, O'Leary OF, Felice D, Bettler B, Dinan TG, Cryan JF. (2012) 'Early-life stress induces visceral hypersensitivity in mice' [Details]
(2012)'An effective dietary method for chronic tryptophan depletion in two mouse strains illuminates a role for 5-HT in nesting behaviour'
Browne CA, Clarke G, Dinan TG, Cryan JF (2012) 'An effective dietary method for chronic tryptophan depletion in two mouse strains illuminates a role for 5-HT in nesting behaviour' [DOI] [Details]
(2012)'Review article: probiotics for the treatment of irritable bowel syndrome - focus on lactic acid bacteria'
Clarke G, Cryan JF, Dinan TG, Quigley EM (2012) 'Review article: probiotics for the treatment of irritable bowel syndrome - focus on lactic acid bacteria' [DOI] [Details]
(2012)'Inhibition of P-glycoprotein Enhances Transport of the Antidepressant Imipramine across the Blood-Brain Barrier: Microdialysis Studies in the Conscious Freely Moving Rat'
O'Brien FE, Clarke G, Fitzgerald P, Dinan TG, Griffin BT, Cryan JF (2012) 'Inhibition of P-glycoprotein Enhances Transport of the Antidepressant Imipramine across the Blood-Brain Barrier: Microdialysis Studies in the Conscious Freely Moving Rat' [DOI] [Details]
(2012)'Menstrual Cycle Influences Toll-Like Receptor Responses'
Dennison U, McKernan DP, Scully P, Clarke G, Cryan J, Dinan T (2012) 'Menstrual Cycle Influences Toll-Like Receptor Responses' [DOI] [Details]
(2011)'Interactions between antidepressants and P-glycoprotein at the blood-brain barrier: Clinical significance of in vitro and in vivo findings'
O'Brien FE, Dinan TG, Griffin BT, Cryan JF; (2011) 'Interactions between antidepressants and P-glycoprotein at the blood-brain barrier: Clinical significance of in vitro and in vivo findings' [DOI] [Details]
(2011)'Exciting Times beyond the Brain: Metabotropic Glutamate Receptors in Peripheral and Non-Neural Tissues'
Julio-Pieper M, Flor PJ, Dinan TG, Cryan JF; (2011) 'Exciting Times beyond the Brain: Metabotropic Glutamate Receptors in Peripheral and Non-Neural Tissues' [DOI] [Details]
(2011)'The microbiome-gut-brain axis: from bowel to behavior'
Cryan JF, O'Mahony SM; (2011) 'The microbiome-gut-brain axis: from bowel to behavior' [DOI] [Details]
(2011)'Differential stress-induced alterations in tryptophan hydroxylase activity and serotonin turnover in two inbred mouse strains'
Browne CA, Clarke G, Dinan TG, Cryan JF; (2011) 'Differential stress-induced alterations in tryptophan hydroxylase activity and serotonin turnover in two inbred mouse strains' [DOI] [Details]
(2011)'Altered peripheral toll-like receptor responses in the irritable bowel syndrome'
McKernan, DP,Gaszner, G,Quigley, EM,Cryan, JF,Dinan, TG; (2011) 'Altered peripheral toll-like receptor responses in the irritable bowel syndrome' [DOI] [Details]
(2011)'Alterations in the central CRF system of two different rat models of comorbid depression and functional gastrointestinal disorders'
Bravo, JA,Dinan, TG,Cryan, JF; (2011) 'Alterations in the central CRF system of two different rat models of comorbid depression and functional gastrointestinal disorders' [DOI] [Details]
(2011)'Is there altered sensitivity to ghrelin-receptor ligands in leptin-deficient mice?: importance of satiety state and time of day'
Finger BC, Schellekens H, Dinan TG, Cryan JF; (2011) 'Is there altered sensitivity to ghrelin-receptor ligands in leptin-deficient mice?: importance of satiety state and time of day' [DOI] [Details]
(2010)'Riluzole Normalizes Early-Life Stress-induced Visceral Hypersensitivity in Rats: Role of Spinal Glutamate Reuptake Mechanisms'
Gosselin, RD; O'Connor, RM; Tramullas, M; Julio-Pieper, M; Dinan, TG; Cryan, JF; (2010) 'Riluzole Normalizes Early-Life Stress-induced Visceral Hypersensitivity in Rats: Role of Spinal Glutamate Reuptake Mechanisms' [DOI] [Details]
(2010)'Lean mean fat reducing ghrelin machine: hypothalamic ghrelin and ghrelin receptors as therapeutic targets in obesity'
Schellekens, H; Dinan, TG; Cryan, JF; (2010) 'Lean mean fat reducing ghrelin machine: hypothalamic ghrelin and ghrelin receptors as therapeutic targets in obesity' [DOI] [Details]
(2010)'Colorectal distension-induced prefrontal cortex activation in the Wistar-Kyoto rat: implications for irritable bowel syndrome'
Gibney, SM; Gosselin, RD; Dinan, TG; Cryan, JF; (2010) 'Colorectal distension-induced prefrontal cortex activation in the Wistar-Kyoto rat: implications for irritable bowel syndrome' [DOI] [Details]
(2010)'Metabotropic glutamate receptor 7: At the interface of cognition and emotion'
O'Connor, RM; Finger, BC; Flor, PJ; Cryan, JF; (2010) 'Metabotropic glutamate receptor 7: At the interface of cognition and emotion' [DOI] [Details]
(2010)'Transient inactivation of the infralimbic cortex induces antidepressant-like effects in the rat'
Slattery, DA; Neumann, I; Cryan, JF; (2010) 'Transient inactivation of the infralimbic cortex induces antidepressant-like effects in the rat' [DOI] [Details]
(2010)'Neonatal maternal separation in the rat impacts on the stress responsivity of central corticotropin-releasing factor receptors in adulthood'
O'Malley, D; Dinan, TG; Cryan, JF; (2010) 'Neonatal maternal separation in the rat impacts on the stress responsivity of central corticotropin-releasing factor receptors in adulthood' [DOI] [Details]
(2010)'Restraint stress-induced brain activation patterns in two strains of mice differing in their anxiety behaviour'
O'Mahony, CM; Sweeney, FF; Daly, E; Dinan, TG; Cryan, JF; (2010) 'Restraint stress-induced brain activation patterns in two strains of mice differing in their anxiety behaviour' [DOI] [Details]
(2010)'5-HT2B receptors modulate visceral hypersensitivity in a stress-sensitive animal model of brain-gut axis dysfunction'
O'Mahony, SM; Bulmer, DC; Coelho, AM; Fitzgerald, P; Bongiovanni, C; Lee, K; Winchester, W; Dinan, TG; Cryan, JF; (2010) '5-HT2B receptors modulate visceral hypersensitivity in a stress-sensitive animal model of brain-gut axis dysfunction' [DOI] [Details]
(2010)'A Sensitive Period of Mice Inhibitory System to Neonatal GABA Enhancement by Vigabatrin is Brain Region Dependent'
Levav-Rabkin, T; Melamed, O; Clarke, G; Farber, M; Cryan, JF; Dinan, TG; Grossman, Y; Golan, HM; (2010) 'A Sensitive Period of Mice Inhibitory System to Neonatal GABA Enhancement by Vigabatrin is Brain Region Dependent' [DOI] [Details]
(2010)'GABAB receptors and depression. Current status'
Cryan JF, Slattery DA; (2010) 'GABAB receptors and depression. Current status' [DOI] [Details]
(2010)'IBs: an epigenetic perspective'
Dinan, Timothy G; Cryan, John; Shanahan, Fergus; Keeling, PW Napoleon; Quigley, Eamonn MM; (2010) 'IBs: an epigenetic perspective' [DOI] [Details]
(2010)'Strain differences in the neurochemical response to chronic restraint stress in the rat: Relevance to depression'
O'Mahony CM, Clarke G, Gibney S, Dinan TG, Cryan JF; (2010) 'Strain differences in the neurochemical response to chronic restraint stress in the rat: Relevance to depression' [DOI] [Details]
(2010)'A Gut Feeling about GABA: Focus on GABAB receptors'
Hyland, NP; Cryan, JF; (2010) 'A Gut Feeling about GABA: Focus on GABAB receptors' [DOI] [Details]
(2010)'Maternal separation as a model of brain-gut axis dysfunction'
O'Mahony, SM; Hyland, NP; Dinan, TG; Cryan, JF; (2010) 'Maternal separation as a model of brain-gut axis dysfunction' [DOI] [Details]
(2010)'Colonic Soluble Mediators from the Maternal Separation Model of Irritable Bowel Syndrome Activate Submucosal Neurons via an Interleukin-6-dependent Mechanism'
O'Malley D, Liston M, Hyland NP, Dinan TG, Cryan JF; (2010) 'Colonic Soluble Mediators from the Maternal Separation Model of Irritable Bowel Syndrome Activate Submucosal Neurons via an Interleukin-6-dependent Mechanism' [DOI] [Details]
(2010)'Marked elevations in pro-inflammatory polyunsaturated fatty acid metabolites in females with irritable bowel syndrome'
Clarke, G; Fitzgerald, P; Hennessy, AA; Cassidy, EM; Quigley, EMM; Ross, P; Stanton, C; Cryan, JF; Dinan, TG; (2010) 'Marked elevations in pro-inflammatory polyunsaturated fatty acid metabolites in females with irritable bowel syndrome' [DOI] [Details]
(2010)'Distinct alterations in colonic morphology and physiology in two rat models of enhanced stress-induced anxiety and depression-like behaviour'
O'Malley, D; Julio-Pieper, M; Gibney, SM; Dinan, TG; Cryan, JF; (2010) 'Distinct alterations in colonic morphology and physiology in two rat models of enhanced stress-induced anxiety and depression-like behaviour' [DOI] [Details]
(2010)'Differential stress-induced alterations of colonic corticotropin-releasing factor receptors in the Wistar Kyoto rat'
O'Malley, D; Julio-Pieper, M; Gibney, SM; Gosselin, RD; Dinan, TG; Cryan, JF; (2010) 'Differential stress-induced alterations of colonic corticotropin-releasing factor receptors in the Wistar Kyoto rat' [DOI] [Details]
(2010)'Neuroscience. A glutamate pathway to faster-acting antidepressants?'
Cryan JF, O'Leary OF; (2010) 'Neuroscience. A glutamate pathway to faster-acting antidepressants?' [DOI] [Details]
(2010)'Progressive ratio responding in an obese mouse model: Effects of fenfluramine'
Finger BC, Dinan TG, Cryan JF; (2010) 'Progressive ratio responding in an obese mouse model: Effects of fenfluramine' [DOI] [Details]
(2010)'A novel role for the metabotropic glutamate receptor-7: modulation of faecal water content and colonic electrolyte transport in the mouse'
Pieper-Julio, M; Hyland, NP; Bravo, JA; Dinan, TG; Cryan, JF; (2010) 'A novel role for the metabotropic glutamate receptor-7: modulation of faecal water content and colonic electrolyte transport in the mouse' [DOI] [Details]
(2010)'Alterations in colonic corticotropin-releasing factor receptors in the maternally separated rat model of irritable bowel syndrome: Differential effects of acute psychological and physical stressors'
O'Malley, D; Dinan, TG; Cryan, JF; (2010) 'Alterations in colonic corticotropin-releasing factor receptors in the maternally separated rat model of irritable bowel syndrome: Differential effects of acute psychological and physical stressors' [DOI] [Details]
(2010)'The effects of repeated social interaction stress on behavioural and physiological parameters in a stress-sensitive mouse strain'
Savignac, HM; Hyland, NP; Dinan, TG; Cryan, JF; (2010) 'The effects of repeated social interaction stress on behavioural and physiological parameters in a stress-sensitive mouse strain' [DOI] [Details]
(2010)'The probiotic Bifidobacterium infantis 35624 displays visceral antinociceptive effects in the rat'
McKernan, DP; Fitzgerald, P; Dinan, TG; Cryan, JF; (2010) 'The probiotic Bifidobacterium infantis 35624 displays visceral antinociceptive effects in the rat' [DOI] [Details]
(2010)'Comparison of Hippocampal Metabotropic Glutamate Receptor 7 (mGlu(7)) mRNA Levels in Two Animal Models of Depression'
O'Mahony, CM; Bravo, J; Dinan, TG; Cryan, JF; (2010) 'Comparison of Hippocampal Metabotropic Glutamate Receptor 7 (mGlu(7)) mRNA Levels in Two Animal Models of Depression' [DOI] [Details]
(2010)'Therapeutic targeting in the silent era: advances in non-viral siRNA delivery'
Guo, J; Fisher, KA; Darcy, R; Cryan, JF; O'Driscoll, C; (2010) 'Therapeutic targeting in the silent era: advances in non-viral siRNA delivery' [DOI] [Full Text] [Details]
(2010)'Leptin-deficient mice retain normal appetitive spatial learning yet exhibit marked increases in anxiety-related behaviours'
Finger, BC; Dinan, TG; Cryan JF; (2010) 'Leptin-deficient mice retain normal appetitive spatial learning yet exhibit marked increases in anxiety-related behaviours' [DOI] [Details]
(2009)'Region specific decrease in glial fibrillary acidic protein immunoreactivity in the brain of a rat model of depression'
Gosselin RD, Gibney S, O'Malley D, Dinan TG, Cryan JF; (2009) 'Region specific decrease in glial fibrillary acidic protein immunoreactivity in the brain of a rat model of depression' [DOI] [Details]
(2009)'Toll-Like Receptor mRNA Expression Is Selectively Increased in the Colonic Mucosa of Two Animal Models Relevant to Irritable Bowel Syndrome'
McKernan, DP,Nolan, A,Brint, EK,O'Mahony, SM,Hyland, NP,Cryan, JF,Dinan, TG; (2009) 'Toll-Like Receptor mRNA Expression Is Selectively Increased in the Colonic Mucosa of Two Animal Models Relevant to Irritable Bowel Syndrome' [DOI] [Details]
(2009)'Chain reactions: Early-life stress alters the metabolic profile of plasma polyunsaturated fatty acids in adulthood'
Clarke, G,O'Mahony, SM,Hennessy, AA,Ross, P,Stanton, C,Cryan, JF,Dinan, TG; (2009) 'Chain reactions: Early-life stress alters the metabolic profile of plasma polyunsaturated fatty acids in adulthood' [DOI] [Details]
(2009)'REGION SPECIFIC DECREASE IN GLIAL FIBRILLARY ACIDIC PROTEIN IMMUNOREACTIVITY IN THE BRAIN OF A RAT MODEL OF DEPRESSION'
Gosselin, RD,Gibney, S,O'Malley, D,Dinan, TG,Cryan, JF; (2009) 'REGION SPECIFIC DECREASE IN GLIAL FIBRILLARY ACIDIC PROTEIN IMMUNOREACTIVITY IN THE BRAIN OF A RAT MODEL OF DEPRESSION' [DOI] [Details]
(2009)'Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort. BMC Gastroenterol'
Clarke, G.,Fitzgerald, P.,Cryan, J. F.,Cassidy, E. M.,Quigley, E. M.,Dinan, T. G.; (2009) 'Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort. BMC Gastroenterol' [Details]
(2009)'A mouse model for visualization of GABA(B) receptors'
Casanova E, Guetg N, Vigot R, Seddik R, Julio-Pieper M, Hyland NP, Cryan JF, Gassmann M, Bettler B; (2009) 'A mouse model for visualization of GABA(B) receptors' [DOI] [Details]
(2009)'Killing the Blues: a role for cellular suicide (apoptosis) in depression and the antidepressant response?'
McKernan DP, Dinan TG, Cryan JF; (2009) 'Killing the Blues: a role for cellular suicide (apoptosis) in depression and the antidepressant response?' [DOI] [Details]
(2009)'Update on smoking cessation therapies'
Glynn DA, Cryan JF, Kent P, Flynn RA, Kennedy MP; (2009) 'Update on smoking cessation therapies' [DOI] [Details]
(2009)'Verapamil in treatment resistant depression: a role for the P-glycoprotein transporter?'
Clarke G, O'Mahony SM, Cryan JF, Dinan TG; (2009) 'Verapamil in treatment resistant depression: a role for the P-glycoprotein transporter?' [DOI] [Details]
(2009)'Irritable bowel syndrome: towards biomarker identification'
Clarke, G; Quigley, EM; Cryan, JF; Dinan, TG; (2009) 'Irritable bowel syndrome: towards biomarker identification' [DOI] [Details]
(2009)'A Distinct Subset of Submucosal Mast Cells Undergoes Hyperplasia Following Neonatal Maternal Separation: A Role In Visceral Hypersensitivity?'
Hyland, NP, Julio-Pieper, M, O'Mahony, SM, Bulmer, DC, Lee, K, Quigley, EM, Dinan, TG, Cryan, JF; (2009) 'A Distinct Subset of Submucosal Mast Cells Undergoes Hyperplasia Following Neonatal Maternal Separation: A Role In Visceral Hypersensitivity?' [DOI] [Details]
(2008)'The Rostral Anterior Cingulate Cortex Modulates The Efficiency of Amygdala-Dependent Fear Learning'
Bissiere, S, Plachta, N, Hoyer, D, McAllister, KH, Olpe, HR, Grace, AA, Cryan, JF; (2008) 'The Rostral Anterior Cingulate Cortex Modulates The Efficiency of Amygdala-Dependent Fear Learning' [DOI] [Details]
(2008)'Enhanced cholinergic-mediated increase in the pro-inflammatory cytokine IL-6 in irritable bowel syndrome: role of muscarinic receptors'
Dinan TG, Clarke G, Quigley EM, Scott LV, Shanahan F, Cryan J, Cooney J, Keeling PW; (2008) 'Enhanced cholinergic-mediated increase in the pro-inflammatory cytokine IL-6 in irritable bowel syndrome: role of muscarinic receptors' [DOI] [Details]
(2008)'Tryptophan catabolism in females with irritable bowel syndrome: relationship to interferon-gamma, severity of symptoms and psychiatric co-morbidity'
Fitzgerald, P,Eugene, MC,Clarke, G,Scully, P,Barry, S,Eamonn, MMQ,Shanahan, F,Cryan, J,Timothy, GD; (2008) 'Tryptophan catabolism in females with irritable bowel syndrome: relationship to interferon-gamma, severity of symptoms and psychiatric co-morbidity' [DOI] [Details]
(2008)'Evaluation of the anxiolytic-like profile of the GABA(B) receptor positive modulator CGP7930 in rodents'
Jacobson, LH,Cryan, JF; (2008) 'Evaluation of the anxiolytic-like profile of the GABA(B) receptor positive modulator CGP7930 in rodents' [DOI] [Details]
(2008)'mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity'
Fendt, M,Schmid, S,Thakker, DR,Jacobson, LH,Yamamoto, R,Mitsukawa, K,Maier, R,Natt, F,Husken, D,Kelly, PH,McAllister, KH,Hoyer, D,van der Putten, H,Cryan, JF,Flor, PJ; (2008) 'mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity' [DOI] [Details]
(2008)'Specific roles of GABAB(1) receptor isoforms in cognition'
Jacobson LH, Kelly PH, Bettler B, Kaupmann K and Cryan JF ; (2008) 'Specific roles of GABAB(1) receptor isoforms in cognition' [Details]
(2008)'Selective activation of metabotropic G-protein-coupled glutamate 7 receptor elicits anxiolytic-like effects in mice by modulating GABAergic neurotransmission'
Stachowicz K, Brañski P, Kłak K, van der Putten H, Cryan JF, Flor PJ, Andrzej P; (2008) 'Selective activation of metabotropic G-protein-coupled glutamate 7 receptor elicits anxiolytic-like effects in mice by modulating GABAergic neurotransmission' [Details]
(2008)'Activation of mGluR7 alters amygdala plasticity and facilitates extinction of fear memories'
5. Fendt, M., Schmid, S., Thakker, D.R., Jacobson, L.H., Yamamota, R. Mitsukawa, K. Maier, R, McAllister, K.H., Hoyer, D. van der Putten, H. Cryan JF and Flor, P.J; (2008) 'Activation of mGluR7 alters amygdala plasticity and facilitates extinction of fear memories' [Details]
(2008)'Early life stress alters behaviour, immunity and microbiota: implications for irritable bowel syndrome and psychiatric illnesses'
2. O' Mahony SM, Marchesi J, Scully P, Codling C, Ceolho A-M, Quigley EMM, Cryan JF, and Dinan TG; (2008) 'Early life stress alters behaviour, immunity and microbiota: implications for irritable bowel syndrome and psychiatric illnesses' [Details]
(2008)'Mglur7 Facilitates Extinction of Aversive Memories and Controls Amygdala Plasticity'
Fendt, M, Schmid, S, Thakker, DR, Jacobson, LH, Yamamoto, R, Mitsukawa, K, Maier, R, Natt, F, Husken, D, Kelly, PH, McAllister, KH, Hoyer, D, van der Putten, H, Cryan, JF, Flor, PJ; (2008) 'Mglur7 Facilitates Extinction of Aversive Memories and Controls Amygdala Plasticity' [DOI] [Details]
(2007)'Amyloid Precursor Protein Knockdown By Sirna Impairs Spontaneous Alternation In Adult Mice'
Senechal, Y, Kelly, PH, Cryan, JF, Natt, F, Dev, KK; (2007) 'Amyloid Precursor Protein Knockdown By Sirna Impairs Spontaneous Alternation In Adult Mice' [DOI] [Details]
(2007)'Evaluation of Reward Processes In An Animal Model of Depression'
Slattery, DA, Markou, A, Cryan, JF; (2007) 'Evaluation of Reward Processes In An Animal Model of Depression' [DOI] [Details]
(2007)'GABAB Receptor positive modulation decreases selective molecular and behavioral effects of cocaine'
Lhuillier L., Mombereau C., *Cryan JF and *Kaupmann, K. ; (2007) 'GABAB Receptor positive modulation decreases selective molecular and behavioral effects of cocaine' [Details]
(2007)'Animal models of mood disorders: recent developments'
Cryan, JF,Slattery, DA; (2007) 'Animal models of mood disorders: recent developments' [Details]
(2007)'GABA(B) receptor-positive modulation-induced blockade of the rewarding properties of nicotine is associated with a reduction in nucleus accumbens Delta FosB accumulation'
Mombereau, C,Lhuillier, L,Kaupmann, K,Cryan, JF; (2007) 'GABA(B) receptor-positive modulation-induced blockade of the rewarding properties of nicotine is associated with a reduction in nucleus accumbens Delta FosB accumulation' [DOI] [Details]
(2007)'Feeling strained? Influence of genetic background on depression-related behavior in mice: A review'
Jacobson LH and Cryan JF; (2007) 'Feeling strained? Influence of genetic background on depression-related behavior in mice: A review' [Details]
(2007)'Behavioural evaluation of mice deficient in GABAB(1) receptor isoforms in tests of unconditioned anxiety'
Jacobson LH, Kaupmann, K., Bettler., Cryan JF ; (2007) 'Behavioural evaluation of mice deficient in GABAB(1) receptor isoforms in tests of unconditioned anxiety' [Details]
(2007)'Antidepressant-like effects of the novel, slelective, 5-HT2C receptor agonist WAY-163909 in rodents'
Rosenzweig-Lipson S, Sabb A, Stack G, Mitchell PJ, Lucki I, Malberg J, Grauer S, Brennan J, Cryan JF, Dunlop J, Barrett J, Marquis KL; (2007) 'Antidepressant-like effects of the novel, slelective, 5-HT2C receptor agonist WAY-163909 in rodents' [Details]
(2007)'Neurogenetics and Behaviour: From Basic Processes to Neuropsychiatric Disorders'
Cryan, JF, Driscoll, P, Waddington, JL; (2007) 'Neurogenetics and Behaviour: From Basic Processes to Neuropsychiatric Disorders' [DOI] [Details]
(2007)'Concise Clinical Pharmacology'
Sahm L., and Cryan J.F.; (2007) 'Concise Clinical Pharmacology' [Details]
(2007)'Emerging use of non-viral RNA interference in the brain'
Cryan JF, Thakker DR, Hoyer D; (2007) 'Emerging use of non-viral RNA interference in the brain' [DOI] [Details]
(2006)'The Rostral Anterior Cingulate Cortex Modulates Depression But Not Anxiety-Related Behaviour In The Rat'
Bissiere, S, McAllister, KH, Olpe, HR, Cryan, JF; (2006) 'The Rostral Anterior Cingulate Cortex Modulates Depression But Not Anxiety-Related Behaviour In The Rat' [DOI] [Details]
(2006)'Gaba(B(1)) Receptor Subunit Isoforms Exert A Differential Influence On Baseline But Not Gaba(B) Receptor Agonist-Induced Changes In Mice'
Jacobson, LH, Bettler, B, Kaupmann, K, Cryan, JF; (2006) 'Gaba(B(1)) Receptor Subunit Isoforms Exert A Differential Influence On Baseline But Not Gaba(B) Receptor Agonist-Induced Changes In Mice' [DOI] [Details]
(2006)'The role of GABAB receptors in depression and the antidepressant response'
Slattery DA, Cryan JF; (2006) 'The role of GABAB receptors in depression and the antidepressant response' [Details]
(2006)'GABA(B(1)) receptor isoforms differentially mediate the acquisition and extinction of aversive taste memories'
Jacobson, LH,Kelly, PH,Bettler, B,Kaupmann, K,Cryan, JF; (2006) 'GABA(B(1)) receptor isoforms differentially mediate the acquisition and extinction of aversive taste memories' [DOI] [Details]
(2006)'GABA(B(1)) receptor subunit isoforms exert a differential influence on baseline but not GABA(B) receptor agonist-induced changes in mice'
Jacobson, LH,Bettler, B,Kaupmann, K,Cryan, JF; (2006) 'GABA(B(1)) receptor subunit isoforms exert a differential influence on baseline but not GABA(B) receptor agonist-induced changes in mice' [DOI] [Details]
(2006)'Differential compartmentalization and distinct functions of GABAB receptor variants'
Vigot R, Barbieri S, Bräuner-Osborne H, Turecek R, Shigemoto R, Zhang YP, Luján R, Jacobson LH, Biermann B, Fritschy JM, Vacher CM, Müller M, Sansig G, Guetg N, Cryan JF, Kaupmann K, Gassmann M, Oertner TG and Bettler B; (2006) 'Differential compartmentalization and distinct functions of GABAB receptor variants' [Details]
(2006)'Interfering with the brain: The utility of siRNA to unravel the pathophysiology of psychiatric and neurological disorders'
Thakker DR, Hoyer D, Cryan JF; (2006) 'Interfering with the brain: The utility of siRNA to unravel the pathophysiology of psychiatric and neurological disorders' [Details]
(2006)'Global down-regulation of gene expression in the brain using RNA interference, with emphasis on monamine transporters and GPCRs: implications for target characterization in psychiatric and neurological disorders'
Hoyer D, Thakker DR, Natt F, Maier R, Huesken D, Müller M, Flor PJ, van der Putten H, Schmutz M, Bilbe, G. and Cryan JF; (2006) 'Global down-regulation of gene expression in the brain using RNA interference, with emphasis on monamine transporters and GPCRs: implications for target characterization in psychiatric and neurological disorders' [Details]
(2006)'GABAB(1) receptor isoforms differentially mediate the acquisition and the extinction of aversive taste learning'
Jacobson LH, Kelly PH, Bettler B, Kaupmann K and Cryan JF; (2006) 'GABAB(1) receptor isoforms differentially mediate the acquisition and the extinction of aversive taste learning' [Details]
(2006)'Metabotropic glutamate receptor subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels; implications for stress-related psychiatric disorders'
Mitsukawa K, Mombereau C, Loetscher E, Uzunov D, van der Putten H, Flor PJ, Cryan JF; (2006) 'Metabotropic glutamate receptor subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels; implications for stress-related psychiatric disorders' [Details]
(2006)'Concomitant deficits in working memory and fear extinction are functionally dissociated from reduced anxiety in mGluR7-deficient mice'
Callaerts-Vegh Z, Beckers T, Baeyens F, Callaerts PF, Cryan JF, Molnar E, D'Hooge R; (2006) 'Concomitant deficits in working memory and fear extinction are functionally dissociated from reduced anxiety in mGluR7-deficient mice' [Full Text] [Details]
(2005)'The GABAB receptor positive modulator GS39783 and the GABAB receptor agonist decrease the rewarding effects of cocaine: Intracranial self-stimulation studies in the rat'
Slattery DA, Markou A. and Cryan JF; (2005) 'The GABAB receptor positive modulator GS39783 and the GABAB receptor agonist decrease the rewarding effects of cocaine: Intracranial self-stimulation studies in the rat' [Details]
(2005)'siRNA-mediated knockdown of the serotonin transporter in the adult mouse brain. '
Thakker DR, Natt F, Husken D, van der Putten H, Maier R, Hoyer D, Cryan JF; (2005) 'siRNA-mediated knockdown of the serotonin transporter in the adult mouse brain. ' [Details]
(2005)'Short and long-term administration of reboxetine, fluoxetine and moclobemide differentially alter behaviour in a modified rat forced swim test'
Cryan JF, Page M.E. and Lucki I.; (2005) 'Short and long-term administration of reboxetine, fluoxetine and moclobemide differentially alter behaviour in a modified rat forced swim test' [Details]
(2005)'Don't worry 'B' happy!: a role for GABA(B) receptors in anxiety and depression. '
Cryan JF, Kaupmann K. ; (2005) 'Don't worry 'B' happy!: a role for GABA(B) receptors in anxiety and depression. ' [Details]
(2005)'Differential sensitivity to the motor and hypothermic effects of the GABA B receptor agonist baclofen in various mouse strains. '
Jacobson LH, Cryan JF; (2005) 'Differential sensitivity to the motor and hypothermic effects of the GABA B receptor agonist baclofen in various mouse strains. ' [Details]
(2005)'The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice. '
Cryan JF, Mombereau C, Vassout A. ; (2005) 'The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice. ' [Details]
(2005)'Blockade of the Group I metabotropic glutamate receptor mGluR5 decreases basal and stress induced increases in cortical norepinephrine in the rat'
Page, M.E., Szeliga, P.J., Gasparini, F. and Cryan, JF ; (2005) 'Blockade of the Group I metabotropic glutamate receptor mGluR5 decreases basal and stress induced increases in cortical norepinephrine in the rat' [Details]
(2005)'GABAB receptor-mediated antidepressant-like effects are serotonin dependent'
Slattery, D., Desrayaud, S. and Cryan JF ; (2005) 'GABAB receptor-mediated antidepressant-like effects are serotonin dependent' [Details]
(2005)'The modified rat forced swim test: Assessing serotonergic influences on depression-related behavior'
Cryan JF, Valentino RJ, Lucki I; (2005) 'The modified rat forced swim test: Assessing serotonergic influences on depression-related behavior' [Details]
(2005)'Altered anxiety and depression-related behaviour in mice lacking GABAB(2) receptor subunits. '
Mombereau C, Kaupmann K, Gassmann M, Bettler B, van der Putten H, Cryan JF. ; (2005) 'Altered anxiety and depression-related behaviour in mice lacking GABAB(2) receptor subunits. ' [Details]
(2005)'Blockade of the mGlu5 receptor decreases basal and stress-induced cortical norepinephrine in rodents. '
Page ME, Szeliga P, Gasparini F, Cryan JF; (2005) 'Blockade of the mGlu5 receptor decreases basal and stress-induced cortical norepinephrine in rodents. ' [Details]
(2005)'The first selective mGluR7 agonist, AMN082 activates receptor signaling via a novel allosteric site and modulates stress parameters in vivo'
Mitsukawa K, Yamamoto R, Ofner S, Nozulak J, Pescott O, Lukic S, Stoehr N, Mombereau C, Kuhn R, McAllister KH, van der Putten H, Cryan JF, Flor PJ; (2005) 'The first selective mGluR7 agonist, AMN082 activates receptor signaling via a novel allosteric site and modulates stress parameters in vivo' [Details]
(2005)'The ascent of mouse: Using mice to model human depression and anxiety'
Cryan JF, Holmes A; (2005) 'The ascent of mouse: Using mice to model human depression and anxiety' [Details]
(2004)'Genetic and pharmacological evidence of a key role for GABAB receptors in the modulation of anxiety and antidepressant-like behaviour'
Mombereau C., Kaupmann K., Froestl, W. Sansig, G. van der Putten H. and Cryan, JF; (2004) 'Genetic and pharmacological evidence of a key role for GABAB receptors in the modulation of anxiety and antidepressant-like behaviour' [Details]
(2004)'Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice. '
Gassmann M., Shaban H., Vigot R., Sansig G., Haller C., Barbieri S., Humeau Y., Schuler V., Muller M., Kinzel B., Klebs K., Schmutz M., Froestl W., Heid J., Kelly P.H., Gentry C., Jaton A.L., Van der Putten H., Mombereau C., Lecourtier L., Mosbacher J., Cryan JF, Fritschy J.M., Luthi A., Kaupmann K., Bettler B. ; (2004) 'Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice. ' [Details]
(2004)'In search of a depressed mouse: utility of models for studying depression-related behavior in genetically modified mice'
Cryan JF, Mombereau C.; (2004) 'In search of a depressed mouse: utility of models for studying depression-related behavior in genetically modified mice' [Details]
(2004)'Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors'
Cryan, JF, O’Leary O., Hirsch, B.R., Jin S-H, Page M.E., Dalvi A., Thomas S.A. and Lucki I.; (2004) 'Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors' [Details]
(2004)'Altered response to benzodiazepine anxiolytics in mice lacking GABAB(1) receptors'
Mombereau C., Kaupmann K., van der Putten H., and Cryan JF; (2004) 'Altered response to benzodiazepine anxiolytics in mice lacking GABAB(1) receptors' [Details]
(2004)'Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines'
Cryan JF, Kelly PH, Chaperon F, Gentsch C, Froestl W, Mombereau C, Lingenhoehl K, Bettler B, Kaupmann K, Spooren WPJM; (2004) 'Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines' [Details]
(2003)'The antidepressant bupropion enhances brain reward function and reverses affective and somatic aspects of nicotine withdrawal'
Cryan J.F, Bruijnzeel A.W., Skjei K.S. and Markou A.; (2003) 'The antidepressant bupropion enhances brain reward function and reverses affective and somatic aspects of nicotine withdrawal' [Details]
(2003)'Withdrawal from chronic amphetamine induces depression-like behavioural effects in rodents'
Cryan J.F., Hoyer D. and Markou A.; (2003) 'Withdrawal from chronic amphetamine induces depression-like behavioural effects in rodents' [Details]
(2003)'Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7'
Cryan J.F., Kelly P.H., Sansig G., Flor P.J. and van Der Putten H.; (2003) 'Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7' [Details]
(2003)'Non-nicotinic neuropharmacological strategies for Smoking Cessation'
Cryan J.F., Gasparini F., van Heeke G. and Markou A.; (2003) 'Non-nicotinic neuropharmacological strategies for Smoking Cessation' [Details]
(2003)'Specific ã-Hydroxybutyrate (GHB) binding sites but loss of pharmacological effects of GHB in GABA-B(1) receptor deficient mice'
Kaupmann K., Cryan J.F., Wellendorph P., Mombereau C., Sansig G., Klebs K., Schmutz, M., Froestl, W. van der Putten, H., Mosbacher, J., Bräuner-Osborne, H., Waldmeier, P., and Bettler, B.; (2003) 'Specific ã-Hydroxybutyrate (GHB) binding sites but loss of pharmacological effects of GHB in GABA-B(1) receptor deficient mice' [Details]
(2002)'Neurochemical and behavioral characterization of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor EMD 68843'
Page M.E., Cryan J.F., Sulivan A., Dalvi A. and Lucki I.; (2002) 'Neurochemical and behavioral characterization of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor EMD 68843' [Details]
(2002)'Noradrenergic lesions differentially alter the antidepressant-like effects of reboxetine'
Cryan, J.F. Page M.E., and Lucki. I.; (2002) 'Noradrenergic lesions differentially alter the antidepressant-like effects of reboxetine' [Details]
(2002)'CREB is essential for upregulation of brain derived neurotrophic factor transcription, but not behavioral or endocrine responses to antidepressant drugs'
Conti A.C., Cryan J.F., Dalvi A., Lucki I. and Blendy J.A.; (2002) 'CREB is essential for upregulation of brain derived neurotrophic factor transcription, but not behavioral or endocrine responses to antidepressant drugs' [Details]
(2002)'Assessing antidepressant activity in rodents: recent developments and future needs. '
Cryan J.F., Markou A., Lucki I. ; (2002) 'Assessing antidepressant activity in rodents: recent developments and future needs. ' [Details]
(2001)'Use of dopamine-beta-hydroxylase-deficient mice to determine the role of norepinephrine in the mechanism of action of antidepressant drugs. '
Cryan J.F., Dalvi A., Hirsch B.R., Jin, S-H, Lucki , I. and Thomas, S.A.; (2001) 'Use of dopamine-beta-hydroxylase-deficient mice to determine the role of norepinephrine in the mechanism of action of antidepressant drugs. ' [Details]
(2000)'Antidepressant-like behavioral effects mediated by 5-Hydroxytryptamine(2C) receptors'
Cryan J.F. and Lucki I.; (2000) 'Antidepressant-like behavioral effects mediated by 5-Hydroxytryptamine(2C) receptors' [Details]
(2000)'Pindolol augmentation of antidepressants: a review and rationale. '
Olver J.S., Cryan J.F., Burrows G.D. and Norman T.R.; (2000) 'Pindolol augmentation of antidepressants: a review and rationale. ' [Details]
(2000)'5-HT1A and Beyond- The role of serotonin and its receptors in depression and the antidepressant response'
Cryan J.F. and Leonard B.E.; (2000) '5-HT1A and Beyond- The role of serotonin and its receptors in depression and the antidepressant response' [Details]
(2000)'Characterization of d-fenfluramine-induced hypothermia- Evidence for multiple sites of action'
Cryan J.F., Harkin A., Kelly J.P. and Leonard B.E.; (2000) 'Characterization of d-fenfluramine-induced hypothermia- Evidence for multiple sites of action' [Details]
(1999)'Metyrapone displays antidepressant-like properties in preclinical paradigms'
Healy D.G., Harkin A. Cryan J.F., Kelly J.P. and Leonard B.E.; (1999) 'Metyrapone displays antidepressant-like properties in preclinical paradigms' [Details]
(1999)'Onset of the effects of the 5-HT1A antagonist, WAY-100635, alone, and in combination with paroxetine, on olfactory bulbectomy and 8-OH-DPAT-induced changes in the rat. '
Cryan J.F., McGrath C., Leonard B.E. and Norman T.R.; (1999) 'Onset of the effects of the 5-HT1A antagonist, WAY-100635, alone, and in combination with paroxetine, on olfactory bulbectomy and 8-OH-DPAT-induced changes in the rat. ' [Details]
(1999)'Comparative effects of serotonergic agonists with varying efficacy at the 5-HT1A receptor on core body temperature: Modification by the selective 5-HT1A receptor antagonist WAY-100635'
Cryan J.F., Kelliher P., Kelly J.P. and Leonard B.E.; (1999) 'Comparative effects of serotonergic agonists with varying efficacy at the 5-HT1A receptor on core body temperature: Modification by the selective 5-HT1A receptor antagonist WAY-100635' [Details]
(1998)'Combining pindolol and paroxetine in an animal model of chronic antidepressant action - Can early onset of action be detected?'
Cryan J.F., McGrath C., Leonard B.E. and Norman T.R.; (1998) 'Combining pindolol and paroxetine in an animal model of chronic antidepressant action - Can early onset of action be detected?' [Details]
(1997)'The effects of the 5-HT1A agonist flesinoxan, in three paradigms for assessing antidepressant potential in the rat. '
Cryan J.F., Redmond A.M., Kelly J.P. and Leonard B.E.; (1997) 'The effects of the 5-HT1A agonist flesinoxan, in three paradigms for assessing antidepressant potential in the rat. ' [Details]
(1996)'Does the serenic eltoprazine have antidepressant potential? -An investigation in three rodent paradigms'
Cryan J.F., Redmond A.M., Kelly J.P. and Leonard B.E.; (1996) 'Does the serenic eltoprazine have antidepressant potential? -An investigation in three rodent paradigms' [Details]

Other Journals

 YearPublication
(2007)'Emerging Use of Non-Viral Rna Interference In The Brain'
Cryan, JF, Thakker, DR, Hoyer, D; (2007) 'Emerging Use of Non-Viral Rna Interference In The Brain' (NA) :411-415. [Details]

Conference Publications

 YearPublication
(2011)Proceedings of the British Pharmacological Society
Lomasney KW, Cryan JF and Hyland NP (2011) Effects of the gut microbiota on colonic secretomotor function Proceedings of the British Pharmacological Society [Details]
(2001)Society for Neuroscience, San Diego, California, USA
O'Leary OF, Page ME, Hirsch BR, Thomas SA, Cryan JF and Lucki I. ; (2001) Role of serotonin in the antidepressant-like effects of SSRIs in the tail suspension test Society for Neuroscience, San Diego, California, USA [Details]
(2002)Society for Neuroscience, Orlando, Florida, USA
O'Leary OF, Cryan JF, Page ME, Hirsch BR, Thomas SA and Lucki I; (2002) Reduced sensitivity to the behavioral and neurochemical effects of SSRIs in norepinephrine-deficient mice Society for Neuroscience, Orlando, Florida, USA [Details]
(2007)Irish Society of Gastroenterology, Dublin
20. O’Malley, D, Hyland, N, Julio-Pieper, M, Gosselin, R, Gibney, S, O’Mahony, S, Dinan, TG and Cryan, JF (2007) Early life stress alters colonic CRF1 and CRF2 receptor expression in the rat Irish Society of Gastroenterology, Dublin [Details]
(2007)European College of Neuropsychopharmacology (ECNP, Vienna 2007)
Mahony, SO,Clarke, G,Mahony, LO,Quigley, E,Cryan, J,Dinan, TG (2007) Depressive behaviours and alterations in the immune and stress response systems following neonatal maternal separation European College of Neuropsychopharmacology (ECNP, Vienna 2007) , pp.280-280 [Details]
(2007)Society for Neuroscience
Gibney SM, Gosselin RD, Fitzgerald P, O’Malley D, Dinan TG and Cryan JF. (2007) Genetic influence on stress- and colonic rectal distension-induced alterations in brain activation: Implications for the pathophysiology of irritable bowel syndrome Society for Neuroscience [Details]
(2007)Society for Neuroscience
Gosselin RD, O'Mahony S, Gibney S, Fitzgerald P, O’Malley D, Dinan TG and Cryan JF. (2007) Altered spinal glial activation in genetically anxious Wistar Kyoto rats: implications for visceral pain in irritable bowel syndrome (IBS) Society for Neuroscience [Details]
(2008)Second Joint International Meeting for Neurogastroenterology and Motilit (Lucerne, Switzerland, November 2008)
Clarke G, Fitzgerald P, Cryan JF, Dinan TG (2008) Increased tryptophan metabolism in irritable bowel syndrome (IBS)–an immune mediated phenomenon? Second Joint International Meeting for Neurogastroenterology and Motilit (Lucerne, Switzerland, November 2008) [Details]
(2008)Digestive Disease Week (San Diego, USA, May 2008)
Clarke G, Fitzgerald P, Cryan JF, Cassidy EM,Quigley EMM, Dinan TG. (2008) Altered kynurenine pathway metabolism in Irritable Bowel Syndrome (IBS)-Evidence of indoleamine 2,3-dioxygenase (IDO) activation in a male cohort Digestive Disease Week (San Diego, USA, May 2008) [Details]
(2008)Digestive Disease Week (San Diego, USA, May 2008)
Fitzgerald P, Clarke G, Scully P, Cryan JF, Shanahan F, Quigley EMM, Cassidy EM, Dinan TG (2008) Tryptophan catabolism in irritable bowel syndrome: Relationship to cytokines, severity and psychiatric comorbidity Digestive Disease Week (San Diego, USA, May 2008) [Details]
(2008)Irish Society of Gastroenterology (Sligo, Ireland, April 2008)
Clarke G, Fitzgerald P, Cassidy E, Cryan JF, Quigley EM, Dinan T (2008) Increased tryptophan degradation along the kynurenine pathway in Irritable Bowel Syndrome (IBS)-Evidence of an immune mediated indoleamine 2,3-dioxygenase (IDO) activation in a male cohort Irish Society of Gastroenterology (Sligo, Ireland, April 2008) [Details]
(2008)International Neuroimmunology Symposium (University College Dublin, Dublin, Ireland, March 2008)
Clarke G, Fitzgerald P, Cryan JF, Cassidy EM,Quigley EMM, Dinan TG (2008) Tryptophan Degradation and Irritable Bowel Syndrome (IBS)-Evidence of an immune mediated indoleamine-2,3-dioxygenase (IDO) activation in a male cohort International Neuroimmunology Symposium (University College Dublin, Dublin, Ireland, March 2008) [Details]
(2008)European College of Neuropsychopharmacology (Workshop on Neuropsychopharmacology for Young Scientists in Europe, Nice, France, March 2008)
Clarke, G,Barry, S,Scully, P,Cryan, JF,Dinan, TG (2008) Evidence of increased tryptophan degradation in psychosis: simultaneous measurement of tryptophan and kynurenine pathway metabolites by HPLC European College of Neuropsychopharmacology (Workshop on Neuropsychopharmacology for Young Scientists in Europe, Nice, France, March 2008) , pp.67-68 [Details]
(2008)European Behavioural Pharmacology Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders (Cork, Ireland, September 2008)
Clarke, G,O'Mahony, S,Hyland, NP,Fitzgerald, P,Dinan, TG,Cryan, JF (2008) Beta3 adrenoceptor modulation of visceral pain - A possible role for the kynurenine pathway? European Behavioural Pharmacology Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders (Cork, Ireland, September 2008) , pp.671-672 [Details]
(2008)Irish Society Gastroenterology, Sligo
Gibney, SM; Gosselin, RD; O’Malley, D; Dinan, TG and Cryan, JF (2008) Imaging distinct patterns of cortical brain activation following Colorectal Distension in an animal model of irritable bowel syndrome Irish Society Gastroenterology, Sligo [Details]
(2008)Eur. Behav. Pharm. Soc, Cork
Gosselin, RD; Gibney, SM; O’Malley, D; Dinan, TG and Cryan, JF (2008) Region specific decrease in glial fibrillary acidic protein (GFAP) immunoreactivity in the brain of a genetic rat model of depression Eur. Behav. Pharm. Soc, Cork [Details]
(2008)Neuroscience Ireland, Galway
O’Malley, D: Julio-Pieper, M; Dinan, T.G. and Cryan, J.F. (2008) Colo-rectal distension induces changes in expression of CRF receptors in the CNS of WKY rats Neuroscience Ireland, Galway [Details]
(2008)Neurogastroenterology & Motility, Lucerne
O’Malley, D, Julio-Pieper, M, Gosselin, RD, Dinan, TG and Cryan, JF (2008) Changes in the expression of CRF receptors in the brain and colon following Colo-rectal distension Neurogastroenterology & Motility, Lucerne [Details]
(2008)Neurogastroenterology & Motility, Lucerne
O’Malley, D, Julio-Pieper, M; Dinan, TG and Cryan, JF (2008) The effects of stress on colonic morphology in two animal models of Irritable Bowel Syndrome Neurogastroenterology & Motility, Lucerne [Details]
(2008)Neurogastroenterology & Motility, Lucerne
Hyland, NP, O’ Callaghan K, O’Malley, D, Lee, K, Dinan, TG, Cryan, JF (2008) Differential cholinergic sensitivity in the enteric nervous system in two models of visceral hypersensitivity Neurogastroenterology & Motility, Lucerne [Details]
(2008)Neurogastroenterology & Motility, Lucerne
Gibney SM, Gosselin RD, O'Malley, D, Dinan TG and Cryan JF (2008) Altered Colonic Rectal Distension-induced activation of the prefrontal cortex in two animal models of Irritable Bowel Syndrome Neurogastroenterology & Motility, Lucerne [Details]
(2008)EURON workshop (Bad Honnef,November 2007)
Clarke, G, Barry, S, Scully, P, Cryan, JF, Dinan, TG; (2008) Simultaneous measurement of tryptophan and its kynurenine pathway metabolites by HPLC: evidence of increased tryptophan degradation in psychosis EURON workshop (Bad Honnef,November 2007) , pp.67-68 [Details]
(2009)Neuroscience Ireland Annual Conference, Dublin
O'Leary OF, O'Connor R and Cryan JF; (2009) Lithium increases hippocampal cell proliferation and alters behaviour in a high anxiety mouse strain: Effects of chronic immobilisation stress Neuroscience Ireland Annual Conference, Dublin [Details]
(2009)European Behavioural Pharmacology Society, Rome, Italy
O'Leary OF, O'Connor R and Cryan JF; (2009) Lithium increases hippocampal cell proliferation and alters behaviour in a high anxiety mouse strain: Effects of chronic immobilization stress European Behavioural Pharmacology Society, Rome, Italy [Details]
(2009)European Behavioural Pharmacology Society, Rome, Italy
Sweeney F, O'Leary OF and Cryan J; (2009) GABAB receptor activation during early adolescence affects adult anxiety behaviour European Behavioural Pharmacology Society, Rome, Italy [Details]
(2009)Neurogastroenterology & Motility, Chicago
O’Malley, D; Dinan, TG and Cryan, JF. (2009) IL-6 activates neurons of the sub-mucosal plexus via a MAPK-dependent mechanism: relevance to irritable bowel syndrome Neurogastroenterology & Motility, Chicago [Details]
(2009)Irish Society for Gastroenterology, Killarney
O’Malley, D; Dinan, TG and Cryan, JF (2009) IL-6 activates neurons in the sub-mucosal plexus via a MAPK-dependent mechanism Irish Society for Gastroenterology, Killarney [Details]
(2009)Translational Health Research Conference, UCC, Cork
O’Malley, D; Dinan, TG and Cryan, JF (2009) IL-6 activates neurons in the sub-mucosal plexus via a MAPK-dependent mechanism Translational Health Research Conference, UCC, Cork [Details]
(2009)Translational Health Research Conference, UCC, Cork
O’Malley, D, Julio-Pieper, M, Dinan, TG and Cryan, JF (2009) Colo-rectal distension induces changes in expression of CRF receptors in the CNS of Wistar Kyoto rats Translational Health Research Conference, UCC, Cork [Details]
(2009)Neuroscience Ireland (Trinity College Dublin, September 2009)
Browne, CA,Clarke, G,Dinan, TG,Cryan, JF (2009) BEHAVIOURAL EFFECTS OF DIETARY TRYPOTPHAN MANIPULATIONS ON C57BL/6J AND BALB/C MICE Neuroscience Ireland (Trinity College Dublin, September 2009) , pp.112-113 [Details]
(2009)Digestive Disease Week (Chicago, USA, June 2009)
Clarke G, Fitzgerald P, Hennessy AA, Cassidy EM, Quigley EMM, Ross P, Stanton C, Cryan JF, Dinan TG. (2009) Polyunsaturated fatty acids contribute to the inflammatory phenotype in irritable bowel syndrome Digestive Disease Week (Chicago, USA, June 2009) [Details]
(2009)European College of Neuropsychopharmacology (Workshop on Neuropsychopharmacology for Young Scientists in Europe,Nice, France, March 2009)
Browne CA, Clarke G., Dinan TG, Cryan JF (2009) Restraint stress alters tryptophan hydroxylase 2 activity in BALB/c mice: relevance to depression European College of Neuropsychopharmacology (Workshop on Neuropsychopharmacology for Young Scientists in Europe,Nice, France, March 2009) [Details]
(2009)Society for Neuroscience, Chicago
Bravo JA, O'Leary OF, Dinan TG and Cryan JF; (2009) Altered stress-related gene expression in the amygdala of a genetic model of anxiety and depression Society for Neuroscience, Chicago [Details]
(2009)Neuroscience Ireland Annual Conference, Dublin
Sweeney F, O'Leary OF and Cryan JF ; (2009) GABAB receptor activation during early adolescence affects adult anxiety behaviour Neuroscience Ireland Annual Conference, Dublin [Details]
(2010)Society for Neuroscience annual meeting, San Diego, CA, USA
O'Leary OF, O¿Connor RM, McGrath B and Cryan JF; (2010) Distinguishing the roles of the ventral versus dorsal hippocampus in stress and lithium-induced changes in cell turnover Society for Neuroscience annual meeting, San Diego, CA, USA [Details]
(2010)European Behavioural Pharmacology Society, Workshop on drugs, psychiatric disorders and neurogenesis, Tours, France
O'Leary OF, O¿Connor RM, McGrath B and Cryan JF; (2010) Lithium-induced increases in cell proliferation are restricted to the ventral hippocampus in stressed BALB/c mice: Relationship to cell survival European Behavioural Pharmacology Society, Workshop on drugs, psychiatric disorders and neurogenesis, Tours, France [Details]
(2010)Neuroscience Ireland Annual Conference, University College Dublin
Pizzo RC, O'Leary OF and Cryan JF; (2010) The medial prefrontal cortex contributes to the anxiolytic effects of the GABAB receptor positive modulator GS39783 Neuroscience Ireland Annual Conference, University College Dublin [Details]
(2010)European Behavioural Pharmacology Society, Workshop on drugs, psychiatric disorders and neurogenesis, Tours, France
Felice D, O'Leary OF, Sweeney F, Pizzo R and Cryan J; (2010) GABAB receptor blockade induces antidepressant-like behavioural effects: Relationship with neurogenesis European Behavioural Pharmacology Society, Workshop on drugs, psychiatric disorders and neurogenesis, Tours, France [Details]
(2010)European College of Neuropsychopharmacology (ECNP) congress, Amsterdam, The Netherlands
O'Leary OF, O¿Connor RM, and Cryan JF; (2010) Lithium preferentially increases neurogenesis in the ventral but not dorsal hippocampus of stressed BALB/c mice European College of Neuropsychopharmacology (ECNP) congress, Amsterdam, The Netherlands [Details]
(2010)7th World Congress on Stress Leiden, The Netherlands
O'Leary OF, O¿Connor RM and Cryan JF; (2010) Desipramine differentially regulates antidepressant-like behaviour and the HPA axis in stressed BALB/c mice 7th World Congress on Stress Leiden, The Netherlands [Details]
(2010)6th Euron Workshop Drugs and the Brain: an update in Psychopharmacology, Braga, Portugal
O'Connor RM, O'Leary OF, Dinan A, Gokul A, Grenham S, Dinan TG and Cryan JF; (2010) Stress-induced Alterations in Hippocampal and Amygdalar microRNAs: Effects of Lithium 6th Euron Workshop Drugs and the Brain: an update in Psychopharmacology, Braga, Portugal [Details]
(2010)ECNP workshop on psychopharmacolgy for young scientists, Nice, France
O'Connor RM, O'Leary OF, Dinan A, Gokul A, Grenham S, Dinan TG and Cryan JF; (2010) Stress-induced alterations in hippocampal microRNAs: effects of lithium ECNP workshop on psychopharmacolgy for young scientists, Nice, France [Details]
(2010)Neurogastroenterology & Motility, Boston
O’Malley, D; Cryan, JF; Dinan, TG. (2010) Corticotropin-Releasing Factor Sensitizes Rat Sub-Mucosal Neurons to the Effects of IL-6 Neurogastroenterology & Motility, Boston [Details]
(2010)Translational Health Research Conference, UCC, Cork
O’Malley, D; Liston, M; Dinan, TG; Cryan, JF; Hyland, NP (2010) CRF1 receptor-dependent activation of submucosal neurones by colonic supernatants from maternally separated rats Translational Health Research Conference, UCC, Cork [Details]
(2010)PNIRS, Dublin
O’Malley, D; Cryan, JF; Dinan, TG (2010) Corticotropin-Releasing Factor-mediated enhancement of Interleukin-6-induced activation of Sub-Mucosal Neurons PNIRS, Dublin [Details]
(2010)DDW, New Orleans
O’Malley, D; Liston, M; Dinan, TG; Cryan, JF; Hyland, NP. (2010) CRF1 receptor-dependent activation of submucosal neurones by colonic supernatants from maternally separated rats DDW, New Orleans [Details]
(2010)Health and Medicine Research Day (Brookfield, Cork, June 2010)
9. Scully P, Clarke G, Grenham S, Fitzgerald P, O’Mahony CM, ,McKernan DP,Tramullas M,Shanahan F, Dinan TG, & Cryan JF (2010) Gender-Dependent Influence of the Gut Microbiome on the Hippocampal 5-HT System Health and Medicine Research Day (Brookfield, Cork, June 2010) [Details]
(2010)Psychoneuroimmunology Research Society (Trinity College, Dublin, June 2010)
Scully P, Clarke G, Grenham S, Fitzgerald P, O’Mahony CM, ,McKernan DP,Tramullas M,Shanahan F, Dinan TG, & Cryan JF (2010) Gender-Dependent Influence of the Gut Microbiome on the Hippocampal 5-HT System Psychoneuroimmunology Research Society (Trinity College, Dublin, June 2010) [Details]
(2010)7th World Congress on Stress (Leiden, Holland, August 2010)
Julio M, O’Mahony C, Clarke G, Bravo J, Dinan TG, Cryan JF (2010) Strain-specific alterations in colon 5-HT levels correlate to defecation responses in chronically stressed mice 7th World Congress on Stress (Leiden, Holland, August 2010) [Details]
(2010)Society for Neuroscience (San Diego, USA, November 2010)
Cryan JF, Clarke G, Grenham S, Scully P, Shanahan F, Dinan TG (2010) The gut microbiome markedly influences hippocampal neurotransmission in the mouse: Role of gender Society for Neuroscience (San Diego, USA, November 2010) [Details]
(2010)Society for Neuroscience (San Diego, USA, November 2010)
Tramullas M, Clarke G, Shanahan F, Dinan TG, Cryan JF (2010) The gut microbiome alters toll-like receptor and cytokine expression levels in the spinal cord: Role of gender Society for Neuroscience (San Diego, USA, November 2010) [Details]
(2011)College of Medicine and Health Research Day (Brookfield, UCC, June 2011)
O’Brien FE, Clarke G, Fitzgerald P, Griffin BT, Cryan JF (2011) An integrated microdialysis model for the analysis of blood-brain barrier drug transport in the conscious freely moving rat College of Medicine and Health Research Day (Brookfield, UCC, June 2011) [Details]
(2011)Health Research Board Watts Medal Competition
O'Mahony E, O'Leary OF, McKernan DP, O¿Malley D, Dinan TG and Cryan JF ; (2011) Investigation of glycogen synthase kinase-3 as a biomarker of schizophrenia and early-life stress Health Research Board Watts Medal Competition [Details]
(2011)The International College of Neuropsychopharmacology (CINP) thematic meeting: Polypharmacy: The Good, The Bad and The Ugly, Salzburg, Austria
O'Leary OF, Zandy S, Dinan TG and Cryan JF; (2011) Increased hippocampal cell proliferation as a molecular mechanism for the therapeutic efficacy of adjunctive lithium therapy in treatment-resistant depression The International College of Neuropsychopharmacology (CINP) thematic meeting: Polypharmacy: The Good, The Bad and The Ugly, Salzburg, Austria [Details]
(2011)Anxiety and Depression, 21st Neuropharmacology Conference, Virginia, USA
O'Leary OF, Zandy S, Dinan TG, Cryan JF; (2011) Adjunctive lithium treatment has antidepressant-like behavioural effects and increases adult hippocampal neurogenesis in a mouse model of treatment resistance Anxiety and Depression, 21st Neuropharmacology Conference, Virginia, USA [Details]
(2011)Anxiety and Depression, 21st Neuropharmacology Conference, Virginia, USA
O'Leary OF, Savignac HM, Felice D., Bettler B., Cryan JF; (2011) GABAB(1) receptor isoforms confer differential susceptibility to the effects of social defeat stress Anxiety and Depression, 21st Neuropharmacology Conference, Virginia, USA [Details]
(2011)European Behavioural Pharmacology society, Amsterdam
O'Leary OF, Zandy S, Dinan TG, and Cryan JF ; (2011) Adjunctive lithium treatment has antidepressant-like behavioural effects and increases hippocampal neurogenesis in a model of treatment-resistant depression European Behavioural Pharmacology society, Amsterdam [Details]
(2011)Wiring the brain: Making connections, Wicklow, Ireland
O'Leary OF, Zandy S, Dinan TG, and Cryan JF; (2011) Increased hippocampal cell proliferation as a molecular mechanism for the therapeutic efficacy of adjunctive lithium therapy in treatment-resistant depression Wiring the brain: Making connections, Wicklow, Ireland [Details]
(2011)DDW, Chicago
O’Malley, D; Quigley, EM; Cryan, JF; Dinan, TG (2011) Plasma derived from patients with irritable bowel syndrome excites rat submucosal neurons via IL-6 and CRFR1 dependent mechanisms DDW, Chicago [Details]
(2011)Neuropharmacology Conference, Virginia, USA, November 10-11
Felice D, O'Leary OF, Pizzo RC, Cryan JF; (2011) Adult hippocampal neurogenesis is increased by a GABAB receptor antagonist : Relevance to antidepressant action Neuropharmacology Conference, Virginia, USA, November 10-11 [Details]
(2011)Anxiety and Depression, 21st Neuropharmacology Conference, Virginia, USA
Felice D, O'Leary OF, Bettler B, Cryan JF; (2011) The role of GABAB(1) receptor subunits in the modulation of early life stress on anxiety and depression-related behaviour in adulthood Anxiety and Depression, 21st Neuropharmacology Conference, Virginia, USA [Details]
(2012)Digestive Disease Week (San Diego, USA, May 2012)
Kennedy PJ, Clarke G, O’Neill A, Groeger JA, Quigley EM, Shanahan F , Cryan JF, Dinan TG (2012) An assessment of cognitive function in irritable bowel syndrome (IBS): Are deficits in episodic memory stress-related and mediated by tryptophan metabolism along the kynurenine pathway? Digestive Disease Week (San Diego, USA, May 2012) [Details]
(2012)Digestive Disease Week (San Diego, USA, May 2012)
Clarke G, Grenham S, Scully P, Fitzgerald P, Shanahan F, Dinan TG, Cryan JF (2012) Regulation of Serotonergic Neurotransmission and Behaviour by the Brain-Gut-Microbiome Axis Digestive Disease Week (San Diego, USA, May 2012) [Details]
(2012)ECNP Workshop on Neuropsychopharmacology, March 15-18 2012, Nice, France
Felice D, O’Leary O.F, Bettler B, Cryan JF (2012) GABAB(1) Receptor Subunit Isoforms Differentially Mediate Susceptibility to Depression-Related Behaviour Following Early-Life Stress ECNP Workshop on Neuropsychopharmacology, March 15-18 2012, Nice, France [Details]
(2010)Gastroenterology
O'Malley, D; Liston, M; Dinan, TG; Cryan, JF; Hyland, NP; (2010) CRF1 receptor-dependent activation of submucosal neurones by colonic supernatants from maternally separated rats Gastroenterology [Details]
(2010)Neuroscience Ireland Annual Conference 2010
Godinho, BMDC; O'Mahony, AM; Ogier, JR; Darcy, R; O'Driscoll, CM; Cryan, JF; (2010) Cyclodextrins as nonviral-vectors for siRNA delivery to the central nervous system Neuroscience Ireland Annual Conference 2010 [Details]
(2010)All-Ireland School of Pharmacy Conference. Queens University, Belfast
O'Mahony, A; Ogier, J; Doyle, D; Darcy, R; Cryan, JF; O'Driscoll, CM; (2010) Modified cyclodextrins as siRNA delivery vectors for neuronal and non-neuronal cells: A study of different structural modifications All-Ireland School of Pharmacy Conference. Queens University, Belfast [Details]
(2010)Gastroenterology
OMahony SM; Savignac HM; O'Brien T; Scully P; Quigley EM; Marchesi, J; O'Toole, PW; Dinan TG; Cryan JF; (2010) Early-life Dysbiosis-Induced Visceral Hypersensitivity in Adulthood Gastroenterology [Details]
(2010)American Association of Pharmaceutical Scientists (AAPS) Annual Conference
O'Mahony, AM; Ogier, J; O'Neill, M; Darcy, R; Cryan, JF; O'Driscoll, CM; (2010) Cyclodextrin-based vectors for siRNA delivery: Effects of pegylation on physical and biological properties in vitro American Association of Pharmaceutical Scientists (AAPS) Annual Conference [Details]
(2009)Gastroenterology
Julio-Pieper M, Hyland NP, Cryan JF, Dinan TG; (2009) Group-III Metabotropic Glutamate Receptors Are Expressed in Rodent Colon: A Role in Cholinergically Induced Electrolyte Secretion Gastroenterology [Details]
(2009)Gastroenterology
Hyland NP, Bongiovanni C, O'Mahony CM, Fitzgerald P, Dinan TG, Cryan JF; (2009) The Combined Effects of Neonatal Psychological Stress and An Anxious Phenotype On Visceral Hypersensitivity and Colonic Function in Rats Gastroenterology [Details]
(2009)Neurogastroenterology and Motility
Hyland NP, Bongiovanni C, O¿Mahony SM, Fitzgerald P, Dinan TG, Cryan JF; (2009) The combined effects of neonatal psychological stress and an anxious phenotype on visceral hypersensitivity and colonic function in rats Neurogastroenterology and Motility [Details]
(2009)Neuroscience
O' Mahony SM, Fitzgerald P, O¿ Sullivan B, Dinan TG, Cryan JF; (2009) Aberrant behavioural and physiological responses to a systemic immune challenge in the wistar kyoto rat Neuroscience [Details]
(2009)Gastroenterology (DDW)
McKernan DP, Nolan A, O'Mahony SM, Hyland NP, Brint E, Dinan TG, Cryan JF.; (2009) Toll-Like Receptor mRNA Expression Is Selectively Increased in the Colonic Mucosa of Two Animal Models of Chronic Stress: Relevance to Irritable Bowel Syndrome Gastroenterology (DDW) [Details]
(2008)Neurogastroenterology Motility
Clarke G, O¿ Mahony SM, Hyland NP, Fitzgerald P, Cryan JF, Dinan TG. ; (2008) Visceral pain and beta3 adrenoceptor modulation a role for the kynurenine pathway? Neurogastroenterology Motility , pp.1-159 [Details]
(2008)Gastroenterology
Hyland NP, Gibney SM, Gosselin RD, Lee K, Dinan TG, Cryan JF. ; (2008) Assessment of colonic secretory function and faecal output in viscerally hypersensitive Wistar Kyoto rats Gastroenterology [Details]
(2008)Neurogastroenterology Motility
Hyland NP, O¿ Callaghan K, O¿Malley D, Lee K, Dinan TG, Cryan JF. ; (2008) Differential cholinergic sensitivity in the enteric nervous system in two models of visceral hypersensitivity Neurogastroenterology Motility , pp.1-159 [Details]
(2008)Neurogastroenterology Motility
Hyland NP, O¿Mahony SM, Bulmer DC, Julio-Pieper M, Bongiovanni C, Dinan TG, Cryan JF. ; (2008) Beta3-adrenoceptor mediated secretion and localisation in the submucosal plexus of descending colon from maternally separated animals Neurogastroenterology Motility , pp.1-159 [Details]
(2008)Neurogastroenterology and Motility
¿ O'Mahony SM, Coelho AM, Bulmer DC, Fitzgerald P, Bongiovanni C, Winchester W, Lee K, Dinan TG, Cryan JF; (2008) Central 5-HT2B Receptors Modulate Visceral Hypersensitivity in a Genetic Model of Irritable Bowel Syndrome Neurogastroenterology and Motility [Details]
(2008)Gastroenterology
Coelho AM, O'Mahony SM, Taylor CM, Wheeldon A, Fitzgerald P, Dinan TG, Cryan JF, Lee K, Winchester WJ. ; (2008) reverses colorectal distension-induced visceral pain behaviours in rat models of acute and chronic visceral hypersensitivity Gastroenterology [Details]
(2008)Neurogastroenterology and Motility (NGM, Lucerne 2008)
Clarke G, Mahony SM, Hyland NP, Fitzgerald P, Cryan JF, Dinan TG; (2008) Visceral pain and beta3 adrenoceptor modulation a role for the kynurenine pathway? Neurogastroenterology and Motility (NGM, Lucerne 2008) [Details]
(2008)Gastroenterology (DDW)
¿ Bulmer DC, O'Mahony SM, Coelho AM, Gray K, Taylor C, Dinan TG, Cryan JF, Lee K, Winchester WJ; (2008) Analgesic effects of 5-HT2B antagonists in pre-clinical models of colorectal pain Gastroenterology (DDW) [Details]
(2008)Gastroenterology
Hyland NP, O¿Mahony SM, Bulmer DC, Lee K, Dinan TG, Cryan JF.; (2008) Do mast cells contribute to visceral hypersensitivity in adult rats following neonatal psychological stress? Gastroenterology , pp.A552-553 [Details]
(2007)Neuropsychopharmacology
Mahony SM, Clarke G, Mahony L, Quigley EMM, Cryan JF, Dinan TG. (2007) Depressive behaviours and alterations in the immune and stress response systems following neonatal maternal separation Neuropsychopharmacology [Details]
(2004)Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference
Thakker DR, Natt F, Husken D, Maier R, Muller M, van der Putten H, Hoyer D, Cryan JF; (2004) Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference , pp.17270-17275 [Details]

Conference Contributions

 YearPublication
(2012)Up-regulation of il-6-expressing macrophages in human colonic mucosal biopsies,
O’Malley, D; Quigley, EM; Cryan, JF; Dinan, TG. (2012) Poster. [Poster Presentation], Up-regulation of il-6-expressing macrophages in human colonic mucosal biopsies, Neurogastroenterology and Motility , 06-SEP-12 - 09-SEP-12
(2012)Neurogastroenterology and Motility, Bologna, Italy, 2012,
Clarke G, Grenham S, Scully P, Fitzgerald P, Shanahan F, Dinan TG, Cryan JF (2012) The Microbiome-Gut-Brain Axis as a Regulator of Serotonergic Neurotransmission and Behaviour. [Poster Presentation], Neurogastroenterology and Motility, Bologna, Italy, 2012, Bologna , 06-SEP-12 - 08-SEP-12
(2012)Neurogastroenterology and Motility, Bologna, Italy, 2012,
Kennedy PJ, Clarke G, O’Neill A, Groeger JA, Quigley EM, Shanahan F , Cryan JF, Dinan TG (2012) An evaluation of neuropsychological performance in Irritable Bowel Syndrome (IBS): Relationship between altered visuo-spatial memory function, salivary cortisol levels and tryptophan metabolism along the kynurenine pathway. [Poster Presentation], Neurogastroenterology and Motility, Bologna, Italy, 2012, Bologna , 06-SEP-12 - 08-SEP-12
(2012)Neuroscience Ireland, RCSI, Dublin, 2012,
O’Brien FE, Clarke G, Dinan TG, Cryan JF, Griffin BT (2012) P-glycoprotein restricts blood-brain barrier transport of the antidepressant escitalopram: converging evidence from in vitro and in vivo studies. [Poster Presentation], Neuroscience Ireland, RCSI, Dublin, 2012, Dublin , 06-SEP-12 - 07-SEP-12
(2012)American Association of Pharmaceutical Scientists Annual Meeting and Exposition (AAPS) Chicago, USA, October 2012,
O’Brien FE, Clarke G, Dinan TG, Cryan JF, Griffin BT (2012) P-glycoprotein limits antidepressant transport across the blood-brain barrier: converging evidence from in vitro and in vivo studies. [Poster Presentation], American Association of Pharmaceutical Scientists Annual Meeting and Exposition (AAPS) Chicago, USA, October 2012, Chicago , 03-OCT-12 - 04-OCT-12
(2012)British Pharmacological Society (BPS) Winter Meeting, London, December 2012,
O’Brien FE, Clarke G, Dinan TG, Cryan JF, Griffin BT (2012) The Influence of P-glycoprotein on the Blood-Brain Barrier Transport of the Antidepressant Escitalopram: Converging Evidence from In Vivo and In Vitro Studies. [Poster Presentation], British Pharmacological Society (BPS) Winter Meeting, London, December 2012, London , 17-DEC-12 - 19-DEC-12
(2007)European College of Neuropsychopharmacology (ECNP), 20th ECNP Congress, Vienna, Austria, September 2007,
O' Mahony SM, Clarke G, O' Mahony L, Quigley EMM, Cryan JF, Dinan TG (2007) Depressive behaviours and alterations in the immune and stress response systems following neonatal maternal separation. [Poster Presentation], European College of Neuropsychopharmacology (ECNP), 20th ECNP Congress, Vienna, Austria, September 2007, Vienna , 13-OCT-07 - 17-OCT-07
(2008)Irish Society of Gastroenterology, Sligo, Ireland, April 2008,
Clarke G, Fitzgerald P, Cassidy E, Cryan JF, Quigley EM, Dinan TG (2008) Increased tryptophan degradation along the kynurenine pathway in Irritable Bowel Syndrome (IBS)-Evidence of an immune mediated indoleamine 2,3-dioxygenase (IDO) activation in a male cohort. [Poster Presentation], Irish Society of Gastroenterology, Sligo, Ireland, April 2008, Sligo , 24-APR-08 - 25-APR-08
(2008)Digestive Disease Week, San Diego, USA, May 2008,
Fitzgerald P, Clarke G, Scully P, Cryan JF, Shanahan F, Quigley EMM, Cassidy EM, Dinan TG (2008) Tryptophan catabolism in irritable bowel syndrome: Relationship to cytokines, severity and psychiatric comorbidity. [Poster Presentation], Digestive Disease Week, San Diego, USA, May 2008, San Diego , 17-MAY-08 - 22-MAY-08
(2008)Digestive Disease Week, San Diego, USA, May 2008,
Clarke G, Fitzgerald P, Cryan JF, Cassidy EM,Quigley EMM, Dinan TG (2008) Altered kynurenine pathway metabolism in Irritable Bowel Syndrome (IBS)-Evidence of indoleamine 2,3-dioxygenase (IDO) activation in a male cohort. [Poster Presentation], Digestive Disease Week, San Diego, USA, May 2008, San Diego , 17-MAY-08 - 22-MAY-08
(2008)European Behavioural Pharmacology Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders, Cork, Ireland, September 2008,
Clarke G, O’Mahony SM, Hyland, NP, Fitzgerald P, Cryan JF, Dinan TG (2008) Beta3 adrenoceptor modulation of visceral pain-a possible role for the kynurenine pathway?. [Poster Presentation], European Behavioural Pharmacology Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders, Cork, Ireland, September 2008, Cork , 25-AUG-08 - 27-AUG-08
(2008)Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland, November 2008,
Clarke G, Fitzgerald P, Cryan JF, Dinan TG. (2008) Increased tryptophan metabolism in irritable bowel syndrome (IBS)–an immune mediated phenomenon?. [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland, November 2008, Lucerne , 06-NOV-08 - 09-NOV-08
(2008)Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland, November 2008,
Clarke G, O’Mahony SM, Hyland NP, Fitzgerald P, Dinan TG, Cryan JF (2008) Visceral pain and beta3 adrenoceptor modulation: a role for the kynurenine pathway?. [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland, November 2008, Lucerne , 06-NOV-08 - 09-NOV-08
(2008)Beta3 Adrenoceptor Modulation of Visceral Pain - A Possible Role For The Kynurenine Pathway?,
Clarke, G, O'Mahony, S, Hyland, NP, Fitzgerald, P, Dinan, TG, Cryan, JF; (2008) Beta3 Adrenoceptor Modulation of Visceral Pain - A Possible Role For The Kynurenine Pathway?,
(2008)International Neuroimmunology Symposium, University College Dublin, Dublin, Ireland, March 2008,
Clarke G, Fitzgerald P, Cryan JF, Cassidy EM,Quigley EMM, Dinan TG (2008) Tryptophan Degradation and Irritable Bowel Syndrome (IBS)-Evidence of an immune mediated indoleamine-2,3-dioxygenase (IDO) activation in a male cohort. [Poster Presentation], International Neuroimmunology Symposium, University College Dublin, Dublin, Ireland, March 2008, Dublin , 13-MAR-08 - 14-MAR-08
(2009)Neuroscience Ireland, Trinity College Dublin, September 2009,
Browne CA, Clarke, G, Dinan TG, Cryan JF. (2009) Behavioural effects of dietary trypotphan manipulations on c57bl/6j and balb/c mice. [Poster Presentation], Neuroscience Ireland, Trinity College Dublin, September 2009, Dublin , 10-SEP-09 - 11-SEP-09
(2009)Digestive Disease Week, Chicago, USA, June 2009,
Clarke G, Fitzgerald P, Hennessy AA, Cassidy EM, Quigley EMM, Ross P, Stanton C, Cryan JF, Dinan TG (2009) Polyunsaturated fatty acids contribute to the inflammatory phenotype in irritable bowel syndrome. [Poster Presentation], Digestive Disease Week, Chicago, USA, June 2009, Chicago , 31-MAY-09 - 03-JUN-09
(2009)European College of Neuropsychopharmacology, Workshop on Neuropsychopharmacology for Young Scientists in Europe, Nice, France, March 2009,
Browne CA, Clarke G., Dinan TG, Cryan JF (2009) Restraint stress alters tryptophan hydroxylase 2 activity in BALB/c mice: relevance to depression. [Poster Presentation], European College of Neuropsychopharmacology, Workshop on Neuropsychopharmacology for Young Scientists in Europe, Nice, France, March 2009, Nice , 05-MAR-09 - 08-MAR-09
(2009)European College of Neuropsychopharmacology, Istanbul, Turkey, September 2009,
Clarke G, O'Mahony SM, Hennessy AA, Ross P, Stanton C, Cryan JF, Dinan TG (2009) Chain reactions: Polyunsaturated fatty acids and the depressive phenotype in maternally separated rodents. [Poster Presentation], European College of Neuropsychopharmacology, Istanbul, Turkey, September 2009, Istanbul , 12-SEP-09 - 16-SEP-09
(2010)7th World Congress on Stress, Leiden, Holland, August 2010,
Julio M, O’Mahony C, Clarke G, Bravo J, Dinan TG, Cryan JF (2010) Strain-specific alterations in colon 5-HT levels correlate to defecation responses in chronically stressed mice. [Poster Presentation], 7th World Congress on Stress, Leiden, Holland, August 2010, Leiden , 25-AUG-12 - 27-AUG-12
(2010)Psychoneuroimmunology Research Society, Trinity College, Dublin, June 2010,
Scully P, Clarke G, Grenham S, Fitzgerald P, O’Mahony CM, ,McKernan DP,Tramullas M,Shanahan F, Dinan TG, & Cryan JF (2010) Gender-Dependent Influence of the Gut Microbiome on the Hippocampal 5-HT System. [Poster Presentation], Psychoneuroimmunology Research Society, Trinity College, Dublin, June 2010, Dublin , 02-JUN-10 - 05-JUN-10
(2010)Health and Medicine Research Day, Brookfield, Cork, June 2010,
Scully P, Clarke G, Grenham S, Fitzgerald P, O’Mahony CM,McKernan DP,Tramullas M,Shanahan F, Dinan TG, & Cryan JF (2010) Gender-Dependent Influence of the Gut Microbiome on the Hippocampal 5-HT System. [Poster Presentation], Health and Medicine Research Day, Brookfield, Cork, June 2010, Cork , 16-JUN-10 - 16-JUN-10
(2010)Society for Neuroscience, San Diego, USA, November 2010,
Cryan JF, Clarke G, Grenham S, Scully P, Shanahan F, Dinan TG (2010) The gut microbiome markedly influences hippocampal neurotransmission in the mouse: Role of gender. [Poster Presentation], Society for Neuroscience, San Diego, USA, November 2010, San Diego , 13-NOV-10 - 17-NOV-10
(2010)Society for Neuroscience, San Diego, USA, November 2010,
Tramullas M, Clarke G, Shanahan F, Dinan TG, Cryan JF (2010) The gut microbiome alters toll-like receptor and cytokine expression levels in the spinal cord: Role of gender. [Poster Presentation], Society for Neuroscience, San Diego, USA, November 2010, San Diego , 13-NOV-10 - 17-NOV-10
(2011)College of Medicine and Health Research Day, UCC, June 2011,
O’Brien FE, Clarke G, Fitzgerald P, Griffin BT, Cryan JF (2011) An integrated microdialysis model for the analysis of blood-brain barrier drug transport in the conscious freely moving rat. [Poster Presentation], College of Medicine and Health Research Day, UCC, June 2011, Cork , 22-JUN-11 - 22-JUN-11
(2012)Digestive Disease Week, San Diego, USA, May 2012,
Clarke G, Grenham S, Scully P, Fitzgerald P, Moloney, RD, Shanahan F, Dinan TG, Cryan JF (2012) Regulation of Serotonergic Neurotransmission and Behaviour by the Brain-Gut-Microbiome Axis. [Poster Presentation], Digestive Disease Week, San Diego, USA, May 2012, San Diego , 19-MAY-12 - 22-MAY-12
(2012)Digestive Disease Week, San Diego, USA, May 2012,
Kennedy PJ, Clarke G, O’Neill A, Groeger JA, Quigley EM, Shanahan F , Cryan JF, Dinan TG (2012) Are deficits in episodic memory stress-related and mediated by tryptophan metabolism along the kynurenine pathway?. [Poster Presentation], Digestive Disease Week, San Diego, USA, May 2012, San Diego , 19-MAY-12 - 22-MAY-12
(2008)European Behavioural Pharmacology Society Meeting,
Cryan, J. F.; (2008) From Mouse to Man: Behavioural Genetics and its Relevance to Psychiatric Disorders. [Conference Organising Committee Member], European Behavioural Pharmacology Society Meeting, Cork, Ireland , 01-JAN-08 - 01-JAN-08
(2008)XXVIth Congress of the Collegium Internationale Neuro-Psychopharmacologium,
Cryan, J. F.; (2008) Corticolimbic dysfunction in stress-related disorders: From mouse to man, from molecule to medicine. [Conference Organising Committee Member], XXVIth Congress of the Collegium Internationale Neuro-Psychopharmacologium, Munich, Germany , 01-JUL-08 - 01-JUL-08
(2008)FENS Meeting,
Cryan, J. F.; (2008) New insights into Cortico-Amygdala interactions: implications for disorders of emotion. [Conference Organising Committee Member], FENS Meeting, Geneva, Switzerland , 01-JUL-08 - 01-JUL-08
(2007)Ninth Annual Meeting of the International Behavioural and Neural Genetics Society,
Cryan, J. F.; (2007) Genetic Approaches to Study Depression and the Antidepressant response. [Conference Organising Committee Member], Ninth Annual Meeting of the International Behavioural and Neural Genetics Society, Doorwerth, The Netherlands , 21-MAY-07 - 25-MAY-07
(2006)Young Scientist Workshop of the European College of Neuropsychopharmacology,
L. Lhuillier, C. Mombereau, J.F. Cryan, K. Kaupmann; (2006) The GABAB receptor positive allosteric modulator GS39783 attenuates selected molecular markers and behavioral effects relevant to both cocaine and nicotine dependence. [Poster Presentation], Young Scientist Workshop of the European College of Neuropsychopharmacology, Nice, France , 01-MAR-06 - 01-MAR-06
(2006)XXVth Congress of the Collegium Internationale Neuro-Psychopharmacologium,
Cryan, J. F.; (2006) Recent advances in understanding the neural substrates of anxiety using rodent models. [Conference Organising Committee Member], XXVth Congress of the Collegium Internationale Neuro-Psychopharmacologium, Chicago , 01-JUL-06 - 01-JUL-06
(2005)The Society for Neuroscience 35th Annual Meeting,
C. Mombereau, L.C. Lhuillier, K. Kaupmann, J.F. Cryan; (2005) The GABAB Receptor-Positive Modulator GS39783 blocks the acquisition of nicotine place preference in the rat. [Poster Presentation], The Society for Neuroscience 35th Annual Meeting, Washington, USA , 01-NOV-05 - 01-NOV-05
(2005)The Society for Neuroscience 35th Annual Meeting,
D.A. Slattery, A. Markou, W. Froestl, J.F. Cryan; (2005) The GABAB receptor-positive modulator GS39783 and the GABAB receptor agonist baclofen attenuate the reward-facilitating effects of cocaine: intracranial self-stimulation studies in the rat. [Poster Presentation], The Society for Neuroscience 35th Annual Meeting, Washington, USA , 01-NOV-05 - 01-NOV-05
(2005)The Society for Neuroscience 35th Annual Meeting,
P.J. Flor, K. Mitsukawa, C. Mombereau, E. Ltscher, D.P. Uzunov, H. van der Putten, J.F. Cryan; (2005) Metabotropic glutamate receptor subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels: implications for stress-related psychiatric disorders. [Poster Presentation], The Society for Neuroscience 35th Annual Meeting, Washington, USA , 01-NOV-05 - 01-NOV-05
(2005)The Society for Neuroscience 35th Annual Meeting,
Mitsukawa, R. Yamamoto, J. Nozulak, S. Ofner, O. Pescott, S. Lukic, N. Stoehr, S. Urwyler, R. Kuhn, P. Herrling, J.F. Cryan, P.J. Flor; (2005) AMN082, the first selective metabotropic glutamate receptor subtype 7 agonist: activation of receptor signaling via an allosteric site in the transmembrane domain. [Poster Presentation], The Society for Neuroscience 35th Annual Meeting, Washington, USA , 01-NOV-05 - 01-NOV-05
(2005)The Society for Neuroscience 35th Annual Meeting,
L.H. Jacobson, K. Kaupmann, B. Bettler, J.F. Cryan; (2005) differential influence of GABAB(1) receptor subunit isoforms on baseline but not GABAB agonist-induced behavioural changes in mice. [Poster Presentation], The Society for Neuroscience 35th Annual Meeting, Washington, USA , 01-NOV-05 - 01-NOV-05
(2005)Young Scientist Workshop of the European College of Neuropsychopharmacology,
D.A. Slattery, C. Mombereau, W. Froestl, A. Markou, K. Kaupmann, and Cryan, J.F; (2005) GABAB receptor positive modulation as a novel therapeutic approach to drug dependence: Blockade of the rewarding and psychostimulant effects of cocaine. [Poster Presentation], Young Scientist Workshop of the European College of Neuropsychopharmacology, Nice, France , 01-MAR-05 - 01-MAR-05
(2005)Experimental Biology Meeting,
D.R. Thakker, F. Natt, D. Hüsken, M. Mller, R. Maier, H. van der Putten, D. Hoyer, Cryan, J.F.; (2005) Behavioural and neurochemical consequences of siRNA-induced knockdown of serotonin and dopamine transporters in the adult mouse brain: Implications for validation of novel therapeutic targets for psychiatric illnesses. [Poster Presentation], Experimental Biology Meeting, San Diego, USA , 01-APR-05 - 01-APR-05
(2005)The American College of Neuropsychopharmacology 44th Annual Meeting,
A. Markou; N.E. Paterson; P.J. Kenny; S. Semenova; J.F.Cryan; (2005) Measuring anhedonia in animals: Reversal by Antidepressant Treatments. [Poster Presentation], The American College of Neuropsychopharmacology 44th Annual Meeting, Hawaii , 01-DEC-05 - 01-DEC-05
(2005)European Brain and Behaviour Society,
Cryan, J. F.; (2005) ETH Zurich on Neurogenetics and Behaviour. [Conference Organising Committee Member], European Brain and Behaviour Society, Dublin, Ireland , 01-SEP-05 - 01-SEP-05
(2003)The Society for Neuroscience 33rd Annual Meeting,
Kaupmann, K., Cryan, J.F., Wellendorph, P. Mombereau, C. Sansig, G. Klebs, K., Schmutz, M., Froestl, W. van der Putten, H., Mosbacher, J., Bräuner-Osborne, H., Waldmeier, P., and Bettler, B.; (2003) Effects of g-hydroxybutyrate in GABA-B receptor deficient mice. [Poster Presentation], The Society for Neuroscience 33rd Annual Meeting, New Orleans, USA , 01-NOV-03 - 01-NOV-03
(2003)The Society for Neuroscience 33rd Annual Meeting,
Cryan, J.F. , Szeliga, P.J., Gasparini, F. Page. M.E.; (2003) Potential anxiolytic-like actions of metabotropic glutamate receptor 5 (mGluR5) antagonists revealed by neurochemical and behavioral studies. [Poster Presentation], The Society for Neuroscience 33rd Annual Meeting, New Orleans, USA , 01-NOV-03 - 01-NOV-03
(2003)Experimental Biology Meeting,
Cryan, J.F. Kelly, P.H. Sansig, G., Flor P.J. and van Der Putten, H.; (2003) Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7 `03 E. [Poster Presentation], Experimental Biology Meeting, San Diego, USA , 01-APR-03 - 01-APR-03
(2008)In search of a depressed mouse: Genetic and behavioural approaches to understand the pathophysiology of depression,
Cryan, J. F. ; (2008) unknown. [Oral Presentation], In search of a depressed mouse: Genetic and behavioural approaches to understand the pathophysiology of depression, University of Newcastle, UK , 01-OCT-08 - 01-OCT-08
(2008)Unknown,
Cryan, J. F. ; (2008) Stress and the Brain-Gut Axis: From the Bowel to Behaviour. [Oral Presentation], Unknown, MacMaster University, Hamilton, Canada , 01-SEP-08 - 01-SEP-08
(2008)Irish Society of Gastroenterology Spring Conference,
Clarke G, Fitzgerald P, Cassidy E, Cryan JF, Quigley EM, Dinan TG; (2008) Increased tryptophan degradation along the kynurenine pathway in Irritable Bowel Syndrome (IBS)-Evidence of an immune mediated indoleamine 2,3-dioxygenase (IDO) activation in a male cohort. [Poster Presentation], Irish Society of Gastroenterology Spring Conference, Sligo, Ireland , 01-APR-08 - 01-APR-08
(2008)Irish Society of Gastroenterology Spring Conference,
Hyland NP, O¿Mahony SM, Bulmer DC, Lee K, Dinan TG & Cryan JF; (2008) Do mast cells contribute to visceral hypersensitivity in adult rats following neonatal psychological stress?. [Poster Presentation], Irish Society of Gastroenterology Spring Conference, Sligo, Ireland , 01-APR-08 - 01-APR-08
(2008)Irish Society of Gastroenterology Spring Conference,
Gibney SM, Gosselin RD, O¿Malley DM, Dinan TG & Cryan JF; (2008) Imaging distinct patterns of cortical brain activation following colorectal distension in an animal model of Irritable Bowel Syndrome. [Poster Presentation], Irish Society of Gastroenterology Spring Conference, Sligo, Ireland , 01-JAN-08 - 01-JAN-08
(2008)International neuroimmunology symposium,
Bravo JA, Dinan TG & Cryan JF; (2008) The effects of the acetylcholinesterase inhibitor pyridostigmine on inflammatory responses in an animal model of irritable bowel syndrome. [Poster Presentation], International neuroimmunology symposium, UCD, Dublin, Ireland , 01-MAR-08 - 01-MAR-08
(2008)Digestive Disease Week,
Clarke G, Fitzgerald P, Cassidy E, Cryan JF, Quigley EM, Dinan TG; (2008) Altered kynurenine pathway metabolism in Irritable Bowel Syndrome (IBS)-Evidence of indoleamine 2,3-dioxygenase (IDO) activation in a male cohort. [Poster Presentation], Digestive Disease Week, San Diego, USA , 01-MAY-08 - 01-MAY-08
(2008)Digestive Disease Week,
Bulmer DC, O' Mahony, SM, Coelho A-M, Gray K, Taylor CM, Dinan TG, Cryan JF, Lee K, Winchester WJ; (2008) Analgesic effects of 5-HT2B antagonists in pre-clinical models of colorectal pain. [Poster Presentation], Digestive Disease Week, San Diego, USA , 01-JAN-08 - 01-JAN-08
(2008)Digestive Disease Week,
Coelho AM, O 'Mahony SM, Taylor CM, Wheeldon A, Fitzgerald P, Dinan T, Cryan JF, Lee K, Winchester WJ.; (2008) Gabapentin reverses colorectal distension-induced visceral pain behaviours in rat models of acute and chronic visceral hypersensitivity. [Poster Presentation], Digestive Disease Week, San Diego, USA , 01-JAN-08 - 01-JAN-08
(2008)Digestive Disease Week,
Hyland NP, O¿Mahony SM, Bulmer DC, Lee K, Dinan TG & Cryan JF; (2008) Do mast cells contribute to visceral hypersensitivity in adult rats following neonatal psychological stress?. [Poster Presentation], Digestive Disease Week, San Diego, USA , 01-JAN-08 - 01-JAN-08
(2008)Digestive Disease Week,
Hyland NP, Gibney SM, Gosselin RD, Lee K, Dinan TG & Cryan JF; (2008) Assessment of colonic secretory function and faecal output in viscerally hypersensitive Wistar Kyoto rats. [Poster Presentation], Digestive Disease Week, San Diego, USA , 01-JAN-08 - 01-JAN-08
(2008)All Ireland Schools of Pharmacy Research Conference,
Savignac HM, Hyland NP, Dinan TG & Cryan JF ; (2008) Social stress induces mild colonic damage and altered anti-inflammatory cytokines in the mouse. [Poster Presentation], All Ireland Schools of Pharmacy Research Conference, Cork, Ireland , 01-APR-08 - 01-APR-08
(2008)British Association for psychoparmacology, Summer meeting,
O¿ Mahony Cliona M, Bravo J, Dinan TG, Cryan JF; (2008) Comparison of stress-induced alterations in hippocampal mGluR7 mRNA in two animal models of depression. [Poster Presentation], British Association for psychoparmacology, Summer meeting, Harrogate, UK , 01-JUL-08 - 01-JUL-08
(2008)6th Meeting on Metabotropic Glutamate receptors,
Fendt, M., Schmid, S., Thakker, D.R., Jacobson, L.H., Yamamota, R. Mitsukawa, K. Maier, R, McAllister, K.H., Hoyer, D. van der Putten, H. Cryan JF and Flor, P.J; (2008) Control of stress- and anxiety- related physiology and behavior by mGluR7 modulation. [Poster Presentation], 6th Meeting on Metabotropic Glutamate receptors, Taormina, Sicily Italy , 01-SEP-08 - 01-SEP-08
(2008)European-Behavioural-Pharmacology-Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders,
Clarke G, O'Mahony S, Hyland NP, Dinan TG & Cryan JF; (2008) Beta3 adrenoceptor modulation of visceral pain - A possible role for the kynurenine pathway?. [Poster Presentation], European-Behavioural-Pharmacology-Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders, Cork, Ireland , 01-AUG-08 - 01-AUG-08
(2008)Unknown,
Cryan, J. F. ; (2008) Genetic and Pharmacological Tools to Unravel the Role of mGluR7 in Stress-related Behavioural Disorders. [Oral Presentation], Unknown, Samuel Lunenfeld Research Center, Mt Sinai Hospital, Univ. Toronto, Canada , 01-SEP-08 - 01-SEP-08
(2008)Unknown,
Cryan, J. F. ; (2008) In vivo Genetic Approaches to Aid in Development of Novel Therapeutic Targets for Stress-related Disorders: Focus on mGluR7. [Oral Presentation], Unknown, Helmholz Zentrum Muenchen, Institute of Developmental Genetics, Munich , 01-JUL-08 - 01-JUL-08
(2008)Unknown,
Cryan, J. F. ; (2008) In vivo Genetic Approaches to Understand the Role of mGluR7 in Stress-Related Disorders. [Oral Presentation], Unknown, Ruhr Univ. Bochum, Germany , 01-JUL-08 - 01-JUL-08
(2008)Unknown,
Cryan, J. F. ; (2008) Silencing the Unquiet Mind: Knockout and RNA Interference-based approaches to Understand Depression and Anxiety. [Oral Presentation], Unknown, Univ Oxford, Dept Pharmacology, UK , 01-JUN-08 - 01-JUN-08
(2008)Unknown,
Cryan, J. F. ; (2008) Silencing the Unquiet Mind: Knockout and RNA Interference-based approaches to Understand Depression and Anxiety. [Oral Presentation], Unknown, Univ. California San Diego , 01-JUN-08 - 01-JUN-08
(2008)Unknown,
Cryan, J. F. ; (2008) Silencing the Unquiet Mind: Knockout and RNA Interference-based approaches to Understand Depression and Anxiety. [Oral Presentation], Unknown, Univ. Liverpool, UK , 01-APR-08 - 01-APR-08
(2008)Unknown,
Cryan, J. F. ; (2008) Silencing the Unquiet Mind: Knockout and RNA Interference-based approaches to Understand Depression and Anxiety. [Oral Presentation], Unknown, Boerhinger Ingelheim, Biberach, Germany, , 01-FEB-08 - 01-FEB-08
(2008)XVIII Asociación Latino- Americana de Farmacología Congress,
Cryan, J. F.; (2008) Novel pharmacological and genetic tools to unravel GABA-Glutamate imbalance in anxiety. [Invited Oral Presentation], XVIII Asociación Latino- Americana de Farmacología Congress, Coquimbo, Chile , 01-OCT-08 - 01-OCT-08
(2008)XXVIth Congress of the Collegium Internationale Neuro-Psychopharmacologium,
Cryan, J. F.; (2008) Genetic and pharmacological tools to unravel the role of mGluR7 in stress-related disorders. [Invited Oral Presentation], XXVIth Congress of the Collegium Internationale Neuro-Psychopharmacologium, Chicago , 01-JUL-08 - 01-JUL-08
(2008)Meeting for Neurogastroenterology and Motility Second Joint International M,
Hyland NP, O¿Mahony SM, Bongiovanni C, Julio-Pieper, M, Bulmer DC, Dinan TG, Cryan JF; (2008) Beta3-adrenoceptor mediated secretion and localisation in the submucosal plexus of descending colon from maternally separated animals. [Poster Presentation], Meeting for Neurogastroenterology and Motility Second Joint International M, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08
(2008)Second Joint International Meeting for Neurogastroenterology and Motility,,
Clarke G., Fitzgerald P, Cryan JF, Dinan TG; (2008) Increased tryptophan metabolism in irritable bowel syndrome (IBS)¿an immune mediated phenomenon?. [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility,, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08
(2008)Second Joint International Meeting for Neurogastroenterology and Motility,
Gibney SM, Gosselin RD, O¿Malley D, Dinan TG & Cryan JF; (2008) Altered colonic rectal distension-induced activation of the prefrontal cortex in two animals models of irritable bowel syndrome (IBS). [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08
(2008)Second Joint International Meeting for Neurogastroenterology and Motility,,
Hyland NP, O¿Callaghan K., O¿Malley D, Dinan TG & Cryan JF; (2008) Differential cholinergic sensitivity in the enteric nervous system in two models of visceral hypersensitivity. [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility,, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08
(2008)Second Joint International Meeting for Neurogastroenterology and Motility,
O¿Mahony SM, Fitzgerald P, Bulmer DC, Coelho AM, Dinan TG & Cryan JF; (2008) Central 5-HT2B receptors modulate visceral hypersensitivity in a genetic model of irritable bowel syndrome. [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08
(2008)Second Joint International Meeting for Neurogastroenterology and Motility,
O¿Malley D, Julio-Pieper M, Dinan TG & Cryan JF; (2008) The effects of stress on colonic morphology in two animal models of irritable bowel syndrome. [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08
(2008)Second Joint International Meeting for Neurogastroenterology and Motility,
O¿Malley D, Julio-Pieper M, Dinan TG & Cryan JF; (2008) CRF receptor expression in the brain and colon of WKY rats following colorectal distension. [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08
(2008)European-Behavioural-Pharmacology-Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders,
Gosselin RD, Gibney S, O'Malley D, Dinan TG & Cryan JF; (2008) Region specific decrease in glial fibrillary acidic protein (GFAP) immunoreactivity in the brain of a genetic rat model of depression. [Poster Presentation], European-Behavioural-Pharmacology-Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders, Cork, Ireland , 01-AUG-08 - 01-AUG-08
(2007)Irish Society of Gastroenterology, Winter Meeting,
Hyland NP, Dinan TG, Cryan JF; (2007) Stress susceptible Wistar Kyoto rats display altered epithelial cholinergic sensitivity in the distal colon. [Poster Presentation], Irish Society of Gastroenterology, Winter Meeting, Dublin, Ireland , 01-DEC-07 - 01-DEC-07
(2007)European Graduate School of Neuroscience workshop,
Clarke G, Barry S, Scully P, Cryan JF, Dinan T; (2007) Simultaneous measurement of tryptophan and it¿s kynurenine pathway metabolites by HPLC: evidence of increased tryptophan degradation in psychosis. [Poster Presentation], European Graduate School of Neuroscience workshop, Bad Honnef, Germany , 01-NOV-07 - 01-NOV-07
(2007)Unknown,
Cryan, J. F. ; (2007) Using novel genetic and pharmacological tools to unravel the role of GABAB receptors in anxiety, depression and drug abuse. [Oral Presentation], Unknown, Univ. Birmingham, UK , 01-FEB-07 - 01-FEB-07
(2007)Unknown,
Cryan, J. F. ; (2007) GABAB receptors Play a Key Role in Neuropsychiatric Disorders: Recent Developments with Novel Genetic and Pharmacological Tools. [Oral Presentation], Unknown, Univ. Copenhagen, Denmark , 01-MAR-07 - 01-MAR-07
(2007)Unknown,
Cryan, J. F. ; (2007) Silencing the Unquiet Mind: Knockout and RNA Interference-based approaches to Understand Depression and Anxiety. [Oral Presentation], Unknown, National Institute of Health, Bethesda USA, Mood and Anxiety Disorders Program Distinguished Lecturer , 01-APR-07 - 01-APR-07
(2007)Unknown,
Cryan, J. F. ; (2007) Silencing the Unquiet Mind: Knockout and RNA Interference-based Approaches to Understand Depression and Anxiety. [Oral Presentation], Unknown, Sepracor Corp, Marlborough MA, USA, , 01-AUG-07 - 01-AUG-07
(2007)19th congress of the European College of Neuropharmacology,
O' Mahony SM, Clarke G, O' Mahony L, Quigley EMM, Cryan JF, Dinan TG; (2007) Depressive behaviours and alterations in the immune and stress response systems following neonatal maternal separation. [Poster Presentation], 19th congress of the European College of Neuropharmacology, Vienna, Austria , 01-JAN-07 - 01-JAN-07
(2007)Brainstorming session, 20th Congress of European College of Neuropsychopharmacology,
Clarke G, Cryan JF, Dinan TG; (2007) An important subplot in the inflammatory theory of depression?. [Poster Presentation], Brainstorming session, 20th Congress of European College of Neuropsychopharmacology, Vienna, Austria , 01-OCT-07 - 01-OCT-07
(2007)The College of Medicine & Health, UCC Joint Health Research Day incorporating Cork University Hospital Research Day,
O' Mahony SM, Fitzgerald P, Coehlo A-M, Taylor C, Cryan JF, Dinan TG.; (2007) Visceral hypersensitivity in two potential animal models of Irritable Bowel Syndrome. [Poster Presentation], The College of Medicine & Health, UCC Joint Health Research Day incorporating Cork University Hospital Research Day, Cork, Ireland , 01-JAN-07 - 01-JAN-07
(2007)The Irish Society of Gastroenterology Winter meeting,
Savignac HM, Hyland NP, Dinan TG, Cryan JF ; (2007) Social stress induces mild colonic damage and altered pro- and anti-inflammatory cytokines in the mouse. [Poster Presentation], The Irish Society of Gastroenterology Winter meeting, Clontarf Castle Hotel, Dublin, Ireland , 01-NOV-07 - 01-NOV-07
(2007)British Neuroscience Association Annual Meeting,
Cryan, J. F.; (2007) Novel therapeutic targets for stress-related disorders. [Invited Oral Presentation], British Neuroscience Association Annual Meeting, Harrogate, UK , 01-APR-07 - 01-APR-07
(2007)Unknown,
Cryan, J. F.; (2007) In search of depressed mouse: Using genetically modified mice to understand depression. [Invited Oral Presentation], Unknown, Doorwerth, The Netherlands , 01-MAY-07 - 01-MAY-07
(2007)Royal Academy of Medicine in Ireland, Summer Meeting,
Cryan, J. F.; (2007) Anatomy of emotion: Corticolimbic modulation of depression and anxiety-related behaviour in animal models. [Invited Oral Presentation], Royal Academy of Medicine in Ireland, Summer Meeting, Cork, Ireland , 01-JUN-07 - 01-JUN-07
(2007)European Graduate School of Neuroscience (EURON),
Browne, CA, O¿Brien, F, Connor TJ, Dinan, TG, & Cryan JF; (2007) Differential LPS-induced cytokine responses in C57BL/6J and BALB/c mice following stress: Relevance to depression. [Poster Presentation], European Graduate School of Neuroscience (EURON), Bad Honnef, Germany , 01-NOV-07 - 01-NOV-07
(2006)Unknown,
Cryan, J. F. ; (2006) Silencing the Unquiet Mind: The Emerging use of RNAi to Understand the Pathophysiology of Neuropsychiatric Disorders. [Oral Presentation], Unknown, Solvay Duphar, Weesp, The Netherlands , 01-OCT-06 - 01-OCT-06
(2006)Uncle Tom's Cabin and the Irish National Tale,
Cryan, J. F. ; (2006) Silencing the Unquiet Mind: The Emerging use of RNAi in Preclinical Neuropsychiatric Research. [Oral Presentation], Uncle Tom's Cabin and the Irish National Tale, International Symposium RNAi in vivo Technologies¿, Munich, Germany , 01-OCT-06 - 01-OCT-06
(2006)Unknown,
Cryan, J. F. ; (2006) Silencing the Unquiet Mind: The Emerging use of RNAi to Understand the Pathophysiology of Neuropsychiatric Disorders. [Oral Presentation], Unknown, Johnson and Johnson, Beerse, Belgium , 01-SEP-06 - 01-SEP-06
(2006)Unknown,
Cryan, J. F.; (2006) Genetic and behavioural approaches to understand the pathophysiology of depression. [Oral Presentation], Unknown, European Science Foundation (ESF) Workshop on Links between Visceral Dysfunction and Affective Disorders, Graz, Austria , 01-AUG-06 - 01-AUG-06
(2006)Unknown,
Cryan, J. F.; (2006) In vivo Genetic Approaches to Understand the Role of mGluR7 in Brain Function. [Oral Presentation], Unknown, Wyeth Pharma, Princeton New Jersey, USA , 01-JUL-06 - 01-JUL-06
(2006)Unknown,
Cryan, J. F.; (2006) Mouse models of psychiatric illness. [Oral Presentation], Unknown, Hi Q Workshop on Assessing Cognition in Animal Models of Huntington Disease, Cambridge, UK , 01-JUL-06 - 01-JUL-06
(2006)Unknown,
Cryan, J. F.; (2006) Silencing the Unquiet Mind: The Emerging use of RNAi to understand the pathophysiology of neurological and psychiatric disorders. [Oral Presentation], Unknown, Roche Pharma AG, Basel, Switzerland , 01-MAR-06 - 01-MAR-06
(2006)Unknown,
Cryan, J. F.; (2006) Modifying Mood: From molecule to mouse to man- A personal perspective on neuropharmacological research in industry and academia. [Oral Presentation], Unknown, Galway-Mayo Institute of Technology, Galway, Ireland , 01-JAN-06 - 01-JAN-06
(2006)European College of Neuropsychopharmacology,
Cryan, J. F.; (2006) Anxiety viewed as a GABA-ergic and glutamatergic disbalance, perspectives for development of new anxiolytic drugs. [Invited Oral Presentation], European College of Neuropsychopharmacology, Paris , 01-SEP-06 - 01-SEP-06
(2006)Neuroscience Ireland Inaugural meeting,
Cryan, J. F.; (2006) Widespread gene knockdown in the adult brain using RNA Interference. [Invited Oral Presentation], Neuroscience Ireland Inaugural meeting, Cork, Ireland , 01-SEP-06 - 01-SEP-06
(2006)XXVth Congress of the Collegium Internationale Neuro-Psychopharmacologium,
Cryan, J. F.; (2006) Academia-Industry Interactions in Neuropsychopharmacology Research. [Invited Oral Presentation], XXVth Congress of the Collegium Internationale Neuro-Psychopharmacologium, Chicago , 01-JUL-06 - 01-JUL-06
(2006)Neuroscience Ireland inaugural conference,
O¿ Mahony Cliona, Daly E, Dinan TG, Cryan JF.; (2006) Genetic influence on stress-induced changes in brain activation in the mouse. [Poster Presentation], Neuroscience Ireland inaugural conference, Cork, Ireland , 01-SEP-06 - 01-SEP-06
(2006)Program No. 67.26. 2006 Neuroscience Meeting Planner,
Bissiere, S., Plachta, N., McAllister, K., Hoyer, D., Olpe, HR, Grace, AA, Cryan, JF; (2006) The rostral anterior cingulate cortex determines the efficiency of amygdala-dependent fear learning. [Poster Presentation], Program No. 67.26. 2006 Neuroscience Meeting Planner, Atlanta, Georgia , 01-JAN-06 - 01-JAN-06
(2006)Program No. 72.17. 2006 Neuroscience Meeting Planner,
Jacobson LH, Kaupmann, K., Bettler., Cryan JF; (2006) GABAB(1) receptor subunit isoforms: A role in anxiety?. [Poster Presentation], Program No. 72.17. 2006 Neuroscience Meeting Planner, Atlanta, Georgia , 01-JAN-06 - 01-JAN-06
(2006)Program No. 72.18. 2006 Neuroscience Meeting Planner. Atlanta, GA: Society for Neuroscience,
Jacobson LH, Kaupmann, K., Bettler., Cryan JF; (2006) The GABAB(1a) receptor subunit isoform mediates antidepressant-like effects: role of 5-HT1A receptors. [Poster Presentation], Program No. 72.18. 2006 Neuroscience Meeting Planner. Atlanta, GA: Society for Neuroscience, Atlanta, Georgia , 01-JAN-06 - 01-JAN-06
(2006)Program No. 370.15. 2006 Neuroscience Meeting Planner,
Fendt, M., Schmid, S., Thakker, D.R., Jacobson, L.H., Yamamota, R. Mitsukawa, K. Maier, R, McAllister, K.H., Hoyer, D. van der Putten, H. Cryan JF and Flor, P.J; (2006) Activation of mGluR7 alters amygdala plasticity and facilitates extinction of fear memories. [Poster Presentation], Program No. 370.15. 2006 Neuroscience Meeting Planner, Atlanta, Georgia , 01-JAN-06 - 01-JAN-06
(2006)2nd Interdisciplinary research day of the college of medicine and health,
O¿ Mahony Cliona, Daly E, Dinan TG, Cryan JF; (2006) Genetic influence on stress-induced changes in brain activation in the mouse. [Poster Presentation], 2nd Interdisciplinary research day of the college of medicine and health, University College Cork, Ireland , 01-NOV-06 - 01-NOV-06
(2006)19th Congress of European College of Neuropsychopharmacology,
Slattery DA, Markou A, Cryan JF; (2006) Evaluation of reward processes in an animal model of depression. [Poster Presentation], 19th Congress of European College of Neuropsychopharmacology, Paris , 01-SEP-06 - 01-SEP-06
(2006)XXVth Congress of the Collegium Internationale Neuro-Psychopharmacologium,
Slattery DA, Markou A, Cryan JF; (2006) Evaluation of reward processes in an animal model of depression. [Poster Presentation], XXVth Congress of the Collegium Internationale Neuro-Psychopharmacologium, Chicago , 01-JUL-06 - 01-JUL-06
(2005)Interfering with the brain : The use of siRNA to understand the roles of genes in neuropsychiatric,
Cryan J.F.; (2005) Interfering with the brain : The use of siRNA to understand the roles of genes in neuropsychiatric. [Invited Lectures (Conference)], Interfering with the brain : The use of siRNA to understand the roles of genes in neuropsychiatric,
(2005)Interfering with Brain Function: Emerging use of siRNA to unravel the roles of genes in psychiatric and neurological disorders,
Cryan J.F.; (2005) Interfering with Brain Function: Emerging use of siRNA to unravel the roles of genes in psychiatric and neurological disorders. [Invited Lectures (Conference)], Interfering with Brain Function: Emerging use of siRNA to unravel the roles of genes in psychiatric and neurological disorders,
(2005)Unknown,
Cryan, J. F.; (2005) Interfering with Brain Function: Emerging use of siRNA to understand the roles of genes in psychiatric disorders. [Oral Presentation], Unknown, University of Innsbruck, Department of Pharmacology and Toxicology, Austria , 01-JAN-05 - 01-JAN-05
(2005)Unknown,
Cryan, J. F.; (2005) Interfering with the brain : The use of siRNA to understand the roles of genes in neuropsychiatric disorders. [Oral Presentation], Unknown, Rockefeller University, New York, USA , 01-NOV-05 - 01-NOV-05
(2005)A role for GABAB receptors in anxiety, depression and drug abuse: Recent developments with novel genetic and pharmacological tools,
Cryan J.F.; (2005) A role for GABAB receptors in anxiety, depression and drug abuse: Recent developments with novel genetic and pharmacological tools. [Invited Lectures (Conference)], A role for GABAB receptors in anxiety, depression and drug abuse: Recent developments with novel genetic and pharmacological tools,
(2005)A role for GABAB receptors in anxiety, depression and drug abuse: Recent developments with novel genetic and pharmacological tools,
Cryan J.F.; (2005) A role for GABAB receptors in anxiety, depression and drug abuse: Recent developments with novel genetic and pharmacological tools. [Invited Lectures (Conference)], A role for GABAB receptors in anxiety, depression and drug abuse: Recent developments with novel genetic and pharmacological tools,
(2005)Interfering with Brain Function: Emerging use of siRNA to understand the roles of genes in psychiatric and neurological disorders,
Cryan J.F.; (2005) Interfering with Brain Function: Emerging use of siRNA to understand the roles of genes in psychiatric and neurological disorders. [Invited Lectures (Conference)], Interfering with Brain Function: Emerging use of siRNA to understand the roles of genes in psychiatric and neurological disorders,
(2005)siRNA-Induced Widespread Gene Knockdown in the Adult Mouse Brain: Utility for studying the molecular basis of neuropsychiatric disorders,
Cryan J.F.; (2005) siRNA-Induced Widespread Gene Knockdown in the Adult Mouse Brain: Utility for studying the molecular basis of neuropsychiatric disorders. [Invited Lectures (Conference)], siRNA-Induced Widespread Gene Knockdown in the Adult Mouse Brain: Utility for studying the molecular basis of neuropsychiatric disorders,
(2005)Interfering with Brain Function: Emerging use of siRNA to understand the roles of genes in psychiatric disorders,
Cryan J.F.; (2005) Interfering with Brain Function: Emerging use of siRNA to understand the roles of genes in psychiatric disorders. [Invited Lectures (Conference)], Interfering with Brain Function: Emerging use of siRNA to understand the roles of genes in psychiatric disorders,
(2005)The American College of Neuropsychopharmacology 44th Annual Meeting,
Cryan, J. F.; (2005) mGluR7: A novel therapeutic target for stress-related disorders. [Invited Oral Presentation], The American College of Neuropsychopharmacology 44th Annual Meeting, Hawaii , 01-DEC-05 - 01-DEC-05
(2004)From Academia to Industry: A Personal Perspective,
Cryan J.F.; (2004) From Academia to Industry: A Personal Perspective. [Invited Lectures (Conference)], From Academia to Industry: A Personal Perspective,
(2003)Unknown,
Cryan, J. F.; (2003) In search of a depressed mouse: models for studying depression-related behaviour in genetically modified mice. [Oral Presentation], Unknown, ETH Zurich , 01-OCT-03 - 01-OCT-03
(2003)Utility of models for studying depression and anxiety-related behavior in genetically modified mice,
Cryan J.F.; (2003) Utility of models for studying depression and anxiety-related behavior in genetically modified mice. [Invited Lectures (Conference)], Utility of models for studying depression and anxiety-related behavior in genetically modified mice,
(2003)In search of a depressed mouse: models for studying depression-related behaviour in genetically modified mice,
Cryan J.F.; (2003) In search of a depressed mouse: models for studying depression-related behaviour in genetically modified mice. [Invited Lectures (Conference)], In search of a depressed mouse: models for studying depression-related behaviour in genetically modified mice,

Abstract

 YearPublication
(2011)Metabotropic Glutamate Receptors in Peripheral and Non-Neural Tissues: Implications for Drug Discovery.
Cryan, JF,Julio-Pieper, M (2011) Metabotropic Glutamate Receptors in Peripheral and Non-Neural Tissues: Implications for Drug Discovery. Abstract [Details]
(2011)Impact of Early-Life Stress on Group III mGlu receptor levels in the rat Hippocampus: Effects of ketamine, Electroconvulsive Shock Therapy and Fluoxetine Treatment.
Connor, RMO,Pusceddu, M,Dinan, TG,Cryan, JF (2011) Impact of Early-Life Stress on Group III mGlu receptor levels in the rat Hippocampus: Effects of ketamine, Electroconvulsive Shock Therapy and Fluoxetine Treatment. Abstract [Details]
(2011)MGLUR7: A THERAPEUTIC TARGET AT THE INTERFACE OF COGNITION AND EMOTION.
Cryan, JF,O'Connor, RM (2011) MGLUR7: A THERAPEUTIC TARGET AT THE INTERFACE OF COGNITION AND EMOTION. Abstract [Details]
(2011)ADJUNCTIVE LITHIUM TREATMENT HAS ANTIDEPRESSANT-LIKE BEHAVIOURAL EFFECTS AND INCREASES HIPPOCAMPAL NEUROGENESIS IN A MODEL OF TREATMENT-RESISTANT DEPRESSION.
O'Leary, OF,Zandy, S,Dinan, TG,Cryan, JF (2011) ADJUNCTIVE LITHIUM TREATMENT HAS ANTIDEPRESSANT-LIKE BEHAVIOURAL EFFECTS AND INCREASES HIPPOCAMPAL NEUROGENESIS IN A MODEL OF TREATMENT-RESISTANT DEPRESSION. Abstract [Details]
(2011)miRNAS AS NOVEL ANTIDEPRESSANT TARGETS: CONVERGING EFFECTS OF ACUTE KETAMINE, ELECTROCONVULSIVE SHOCK THERAPY AND CHRONIC FLUOXETINE TREATMENTS.
Connor, RMO,Dinan, TG,Cryan, JF (2011) miRNAS AS NOVEL ANTIDEPRESSANT TARGETS: CONVERGING EFFECTS OF ACUTE KETAMINE, ELECTROCONVULSIVE SHOCK THERAPY AND CHRONIC FLUOXETINE TREATMENTS. Abstract [Details]
(2006)Molecular dissection of the role of GABA(B1) receptor isoforms 1a and 1b in anxiety-related behaviour.
Jacobson, LH,Neijt, HC,Bettler, B,Kaupmann, K,Cryan, JF (2006) Molecular dissection of the role of GABA(B1) receptor isoforms 1a and 1b in anxiety-related behaviour. Abstract [Details]
(2006)The infralimbic cortex modulates stress-induced coping behaviour - implications for depression.
Slattery, DA,Cryan, JF (2006) The infralimbic cortex modulates stress-induced coping behaviour - implications for depression. Abstract [Details]
(2006)Evaluation of reward processes in an animal model of depression.
Slattery, DA,Markou, A,Cryan, JF (2006) Evaluation of reward processes in an animal model of depression. Abstract [Details]
(2006)Emerging use of RNA interference to understand the role of genes in anxiety.
Cryan, JF,Thakker, DR,van der Putten, H,Flor, PJ,Hoyer, D (2006) Emerging use of RNA interference to understand the role of genes in anxiety. Abstract [Details]
(2006)Evaluation of reward processes in an animal model of depression.
Slattery, DA,Markou, A,Cryan, JF (2006) Evaluation of reward processes in an animal model of depression. Abstract [Details]
(2006)Molecular dissection of the role of GABA1 receptor isoforms 1a and 1b in anxiety-related behaviour.
Jacobson, LH,Neijt, HC,Bettler, B,Kaupmann, K,Cryan, JF (2006) Molecular dissection of the role of GABA1 receptor isoforms 1a and 1b in anxiety-related behaviour. Abstract [Details]
(2007)Assessing the genetic influence on anxiety behaviour and stress-induced brain activation in the mouse.
Mahony, CMO,Sweeney, F,Daly, E,Dinan, TG,Cryan, JF (2007) Assessing the genetic influence on anxiety behaviour and stress-induced brain activation in the mouse. Abstract [Details]
(2008)The effects of acetylcholinesterase inhibitor pyridostigmine on inflammatory responses in an animal model of irritable bowel syndrome.
Bravo, JA,Dinan, TG,Cryan, JF (2008) The effects of acetylcholinesterase inhibitor pyridostigmine on inflammatory responses in an animal model of irritable bowel syndrome. Abstract [Details]
(2008)Tryptophan Degradation and Irritable Bowel Syndrome (IBS) - Evidence of an immune mediated indoleamine-2,3-dioxygenase (IDO) activation in a male cohort.
Clarkc, G,Fitzgerald, P,Cryan, JF,Dinan, TG (2008) Tryptophan Degradation and Irritable Bowel Syndrome (IBS) - Evidence of an immune mediated indoleamine-2,3-dioxygenase (IDO) activation in a male cohort. Abstract [Details]
(2008)Genetic influences on hippocampal susceptibility to cell death following immune activation.
O'Connor, RM,McKernan, DR,Browne, C,Dinan, TG,Cryan, JF (2008) Genetic influences on hippocampal susceptibility to cell death following immune activation. Abstract [Details]
(2008)Aberrant cytokine response to stress in BALB/c mice after lipopolysaccharide (LPS) challenge: relevance of tryptophan hydroxylase 2.
Browne, CA,O'Brien, F,Connor, TJ,Cryan, JF (2008) Aberrant cytokine response to stress in BALB/c mice after lipopolysaccharide (LPS) challenge: relevance of tryptophan hydroxylase 2. Abstract [Details]
(2008)Aberrant LPS-induced cytokine responses in mice following stress: Relevance to major depression.
Browne, CA,O'Brien, F,Connor, TJ,Dinan, TG,Cryan, JF (2008) Aberrant LPS-induced cytokine responses in mice following stress: Relevance to major depression. Abstract [Details]
(2008)Genetic and pharmacological tools to unravel the role of mGluR7 in stress-related disorders.
Cryan, J (2008) Genetic and pharmacological tools to unravel the role of mGluR7 in stress-related disorders. Abstract [Details]
(2008)Region specific decrease in glial fibrillary acidic protein (GFAP) immunoreactivity in the brain of a genetic rat model of depression.
Gosselin, RD,Gibney, S,O'Malley, D,Dinan, TG,Cryan, JF (2008) Region specific decrease in glial fibrillary acidic protein (GFAP) immunoreactivity in the brain of a genetic rat model of depression. Abstract [Details]
(2008)Gobal down-regulation of gene expression in the brain using RNA interference, with emphasis on neuropeptides, GPCRS and monoamine transporters.
Hoyer, D,Thakker, DR,Natt, F,Maier, R,Huesken, D,Mueller, M,Flor, PJ,van der Putten, H,Schmutz, M,Cryan, JF (2008) Gobal down-regulation of gene expression in the brain using RNA interference, with emphasis on neuropeptides, GPCRS and monoamine transporters. Abstract [Details]
(2008)Differential expression of mGluR7 in two animal models of depression.
O'Mahony, CM,Bravo, J,Dinan, TG,Cryan, JF (2008) Differential expression of mGluR7 in two animal models of depression. Abstract [Details]
(2008)The effects of acute and chronic stress on mGluR7 and BDNF gene expression in two inbred strains of mice which differ in emotionality.
O'Mahony, CM,Dinan, TG,Cryan, JF (2008) The effects of acute and chronic stress on mGluR7 and BDNF gene expression in two inbred strains of mice which differ in emotionality. Abstract [Details]
(2008)Altered stress-related gene expression in the hippocampus of a gentetic model of anxiety & depression.
Bravo, JA,Dinan, TG,Cryan, JF (2008) Altered stress-related gene expression in the hippocampus of a gentetic model of anxiety & depression. Abstract [Details]
(2008)BALB/c mice as a model of aberrant stress-induced cytokine expression: Relevence to major depression.
Browne, CA,O'Brien, F,Connor, TJ,Dinan, TG,Cryan, JF (2008) BALB/c mice as a model of aberrant stress-induced cytokine expression: Relevence to major depression. Abstract [Details]
(2008)Differential activation of the prefrontal cortex in response to stress and colonic rectal distension in a genetically susceptible model of depression & irritable bowel syndrome (IBS).
Gibney, SM,Gosselin, RD,Dinan, TG,Cryan, JF (2008) Differential activation of the prefrontal cortex in response to stress and colonic rectal distension in a genetically susceptible model of depression & irritable bowel syndrome (IBS). Abstract [Details]
(2009)Altered expression of hippocampal mGLUR7 mRNA in a model of depression.
O'Mahony, C,Dinan, TG,Cryan, JF (2009) Altered expression of hippocampal mGLUR7 mRNA in a model of depression. Abstract [Details]
(2009)Mice are resistant to early-life stress-induced alterations in adult behaviour.
Savignac, HM,Dinan, TG,Cryan, JF (2009) Mice are resistant to early-life stress-induced alterations in adult behaviour. Abstract [Details]
(2010)Stress-induced alterations in hippocampal microRNAs: effects of lithium.
O'Connor, RM,O'Leary, OF,Dinan, A,Grenham, S,Dinan, TG,Cryan, JF (2010) Stress-induced alterations in hippocampal microRNAs: effects of lithium. Abstract [Details]
(2010)Stress-induced alterations in hippocampal and amygdalar microRNAs: effects of lithium.
O'Connor, RM,O'Leary, OF,Dinan, A,Gokul, A,Dinan, TG,Cryan, JF (2010) Stress-induced alterations in hippocampal and amygdalar microRNAs: effects of lithium. Abstract [Details]
(2010)Animal models of co-morbid depression and irritable bowel syndrome.
Cryan, J,Bravo, JA,Clarke, G,Hyland, NP,O'Malley, D,O'Mahony, D,Julio-Pieper, M,McKernan, DP,Tramullas, M,Dinan, TG (2010) Animal models of co-morbid depression and irritable bowel syndrome. Abstract [Details]
(2010)Increased serotonin 2c receptor editing in a mouse model of obesity.
Schellekens, H,Dinan, TO,Cryan, JF (2010) Increased serotonin 2c receptor editing in a mouse model of obesity. Abstract [Details]
(2010)Lithium preferentially increases neurogenesis in the ventral but not dorsal hippocampus of stressed BALB/c mice.
O'Leary, OF,O'Connor, RM,Cryan, JF (2010) Lithium preferentially increases neurogenesis in the ventral but not dorsal hippocampus of stressed BALB/c mice. Abstract [Details]
(2010)Peripheral metabotropic glutamate receptors: focus on the role of mGluR7 in brain-gut axis regulation.
Julio-Pieper, M,Hyland, NP,Bravo, JA,Dinan, TG,Cryan, JF (2010) Peripheral metabotropic glutamate receptors: focus on the role of mGluR7 in brain-gut axis regulation. Abstract [Details]
(2010)LITHIUM-INDUCED INCREASES IN CELL PROLIFERATION ARE RESTRICTED TO THE VENTRAL HIPPOCAMPUS IN STRESSED BALB/C MICE: RELATIONSHIP TO CELL SURVIVAL.
O'Leary, OF,O'Connor, RM,McGrath, B,Cryan, JF (2010) LITHIUM-INDUCED INCREASES IN CELL PROLIFERATION ARE RESTRICTED TO THE VENTRAL HIPPOCAMPUS IN STRESSED BALB/C MICE: RELATIONSHIP TO CELL SURVIVAL. Abstract [Details]
(2010)GABAB RECEPTOR BLOCKADE INDUCES ANTIDEPRESSANT-LIKE BEHAVIOURAL EFFECTS: RELATIONSHIP WITH NEUROGENESIS.
Felice, D,O'Leary, OF,Sweeney, FF,Pizzo, RC,Cryan, JF (2010) GABAB RECEPTOR BLOCKADE INDUCES ANTIDEPRESSANT-LIKE BEHAVIOURAL EFFECTS: RELATIONSHIP WITH NEUROGENESIS. Abstract [Details]
(2010)BIFIDOBACTERIUM INFANTIS 35624 REDUCES VISCERAL HYPERACTIVITY IN A RAT MODEL OF CHRONIC STRESS.
McKernan, DP,Bongiovanni, C,Fitzgerald, P,Dinan, TG,Cryan, JF (2010) BIFIDOBACTERIUM INFANTIS 35624 REDUCES VISCERAL HYPERACTIVITY IN A RAT MODEL OF CHRONIC STRESS. Abstract [Details]
(2010)LITHIUM INCREASES HIPPOCAMPAL CELL PROLIFERATION AND ALTERS BEHAVIOUR IN A HIGH ANXIETY MOUSE STRAIN: EFFECTS OF CHRONIC IMMOBILISATION STRESS.
O'Leary, OF,O'Connor, RM,Cryan, JF (2010) LITHIUM INCREASES HIPPOCAMPAL CELL PROLIFERATION AND ALTERS BEHAVIOUR IN A HIGH ANXIETY MOUSE STRAIN: EFFECTS OF CHRONIC IMMOBILISATION STRESS. Abstract [Details]
(2010)Neural circuitry underlying GABA-B receptor positive modulator-induced effects on anxiety behaviour in the mouse.
Pizzo, RC,Cucinotta, AL,Cryan, JF (2010) Neural circuitry underlying GABA-B receptor positive modulator-induced effects on anxiety behaviour in the mouse. Abstract [Details]
(2010)GABA(B) RECEPTOR ACTIVATION DURING EARLY ADOLESCENCE AFFECTS ADULT ANXIETY BEHAVIOUR.
Sweeney, FF,O'Leary, OF,Cryan, JF (2010) GABA(B) RECEPTOR ACTIVATION DURING EARLY ADOLESCENCE AFFECTS ADULT ANXIETY BEHAVIOUR. Abstract [Details]
(2010)ABERRANT BEHAVIOURAL AND PHYSIOLOGICAL RESPONSES TO A SYSTEMIC IMMUNE CHALLENGE IN THE WISTAR KYOTO RAT.
O'Mahony, SM,Fitzgerald, P,O'Sullivan, B,Dinan, TG,Cryan, JF (2010) ABERRANT BEHAVIOURAL AND PHYSIOLOGICAL RESPONSES TO A SYSTEMIC IMMUNE CHALLENGE IN THE WISTAR KYOTO RAT. Abstract [Details]
(2011)ALTERED TOLL-LIKE RECEPTOR RESPONSES IN SCHIZOPHRENIA AND BIPOLAR DISORDER PATIENTS.
McKernan, DP,Dennison, U,Cryan, JF,Dinan, TG (2011) ALTERED TOLL-LIKE RECEPTOR RESPONSES IN SCHIZOPHRENIA AND BIPOLAR DISORDER PATIENTS. Abstract [Details]
(2011)CHRONIC SOCIAL DEFEAT STRESS INDUCES DIFFERENTIAL CHANGES IN HIPPOCAMPAL MICRORNA EXPRESSION IN TWO INBRED MOUSE STRAINS DIFFERING IN ANXIETY BEHAVIOUR.
O'Connor, RM,Savignac, HM,Finger, BC,Dinan, TG,Cryan, JF (2011) CHRONIC SOCIAL DEFEAT STRESS INDUCES DIFFERENTIAL CHANGES IN HIPPOCAMPAL MICRORNA EXPRESSION IN TWO INBRED MOUSE STRAINS DIFFERING IN ANXIETY BEHAVIOUR. Abstract [Details]
(2011)THE MEDIAL PREFRONTAL CORTEX CONTRIBUTES TO THE ANXIOLYTIC EFFECTS OF THE GABA(B) RECEPTOR POSITIVE MODULATOR GS39783.
Pizzo, RC,O'Leary, OF,Cryan, JF (2011) THE MEDIAL PREFRONTAL CORTEX CONTRIBUTES TO THE ANXIOLYTIC EFFECTS OF THE GABA(B) RECEPTOR POSITIVE MODULATOR GS39783. Abstract [Details]
(2011)THE UTILITY OF LEPTIN-DEFICIENT MICE FOR STUDYING THE EFFECTS OF GHRELIN RECEPTOR AGONISTS AND ANTAGONISTS ON FOOD INTAKE.
Finger, BC,Dinan, TG,Cryan, JF (2011) THE UTILITY OF LEPTIN-DEFICIENT MICE FOR STUDYING THE EFFECTS OF GHRELIN RECEPTOR AGONISTS AND ANTAGONISTS ON FOOD INTAKE. Abstract [Details]
(2011)CYCLODEXTRINS AS NONVIRAL-VECTORS FOR siRNA DELIVERY TO THE CENTRAL NERVOUS SYSTEM.
Godinho, BMDC,O'Mahony, AM,Ogier, JR,Darcy, R,O'Driscoll, CM,Cryan, JF (2011) CYCLODEXTRINS AS NONVIRAL-VECTORS FOR siRNA DELIVERY TO THE CENTRAL NERVOUS SYSTEM. Abstract [Details]
(2011)DIFFERENTIAL STRESS-INDUCED ALTERATIONS OF THE SEROTONERGIC SYSTEM OF TWO INBRED MOUSE STRAINS, BALB/C AND C57BL/6 J MICE, WHICH DIFFER IN FUNCTIONAL POLYMORPHISMS OF THE TPH2 GENE.
Browne, CA,Clarke, G,Dinan, TG,Cryan, JF (2011) DIFFERENTIAL STRESS-INDUCED ALTERATIONS OF THE SEROTONERGIC SYSTEM OF TWO INBRED MOUSE STRAINS, BALB/C AND C57BL/6 J MICE, WHICH DIFFER IN FUNCTIONAL POLYMORPHISMS OF THE TPH2 GENE. Abstract [Details]
(2011)Olanzapine-induced weight gain is associated with increased hypothalamic ghrelin receptor expression.
Schellekens, H,Davey, KJ,O'Mahony, SM,Dinan, TG,Cryan, JF (2011) Olanzapine-induced weight gain is associated with increased hypothalamic ghrelin receptor expression. Abstract [Details]
(2011)LEPTIN-DEFICIENT MICE RETAIN NORMAL APPETITIVE SPATIAL AND OPERANT LEARNING YET EXHIBIT MARKED INCREASES IN ANXIETY-RELATED BEHAVIOURS.
Finger, BC,Dinan, TG,Cryan, JF (2011) LEPTIN-DEFICIENT MICE RETAIN NORMAL APPETITIVE SPATIAL AND OPERANT LEARNING YET EXHIBIT MARKED INCREASES IN ANXIETY-RELATED BEHAVIOURS. Abstract [Details]
(2011)SPINAL TOLL-LIKE RECEPTOR mRNA EXPRESSION IS SELECTIVELY INCREASED IN AN ANIMAL MODEL OF VISCERAL PAIN: RELEVANCE TO IRRITABLE BOWEL SYNDROME.
Tramullas, M,Dinan, TG,Cryan, JF (2011) SPINAL TOLL-LIKE RECEPTOR mRNA EXPRESSION IS SELECTIVELY INCREASED IN AN ANIMAL MODEL OF VISCERAL PAIN: RELEVANCE TO IRRITABLE BOWEL SYNDROME. Abstract [Details]

Editorial

 YearPublication
(2012)Stress, anxiety and depression: Toward new treatment strategies.
Markou, A,Cryan, JF (2012) Stress, anxiety and depression: Toward new treatment strategies. Editorial [DOI] [Details]
(2011)The microbiome-gut-brain axis: from bowel to behavior.
Cryan, JF,O'Mahony, SM; (2011) The microbiome-gut-brain axis: from bowel to behavior. Editorial [DOI] [Details]
(2010)A Glutamate Pathway to Faster-Acting Antidepressants?.
Cryan, JF,O'Leary, OF; (2010) A Glutamate Pathway to Faster-Acting Antidepressants?. Editorial [DOI] [Details]
(2007)Neurogenetics and behaviour: From basic processes to neuropsychiatric disorders.
Cryan, JF,Driscoll, P,Waddington, JL; (2007) Neurogenetics and behaviour: From basic processes to neuropsychiatric disorders. Editorial [DOI] [Details]

Newspaper Articles

 YearPublication
(2010)Banning mephedrone won't stop next wave.
Keating J.J., Cryan J.F.; (2010) Banning mephedrone won't stop next wave. Irish Examiner: Newspaper Articles [Details]

Review Articles

 YearPublication
(2009)Irritable bowel syndrome: towards biomarker identification.
Clarke G, Quigley EMM, Cryan JF, Dinan TG (2009) Irritable bowel syndrome: towards biomarker identification. Review Articles [Details]
(2011)Brain-Gut-Microbe communication in health and disease.
Grenham S, Clarke G, Cryan JF, Dinan TG (2011) Brain-Gut-Microbe communication in health and disease. Review Articles [Details]
(2012)Gut Memories: Towards a Cognitive Neurobiology of Irritable Bowel Syndrome.
Kennedy P, Clarke G, Groeger J, Quigley EMM, Cryan J, Dinan T (2012) Gut Memories: Towards a Cognitive Neurobiology of Irritable Bowel Syndrome. Review Articles [Details]
(2012)Probiotics for the Treatment of Irritable Bowel Syndrome: Focus on Lactic Acid Bacteria.
Clarke G, Cryan JF, Dinan TG, Quigley EM (2012) Probiotics for the Treatment of Irritable Bowel Syndrome: Focus on Lactic Acid Bacteria. Review Articles [Details]
(2005)New medications for smoking cessation: beyond NRT and bupropion.
Cryan J.F.; (2005) New medications for smoking cessation: beyond NRT and bupropion. Review Articles [Details]
(2005)mGluR7 Plays a Key Role in the Modulation of Anxiety Behavior: Evidence from mGluR7 Knockout Mice and siRNA-induced Knockdown in the Adult Mouse Brain.
Cryan J.F.; (2005) mGluR7 Plays a Key Role in the Modulation of Anxiety Behavior: Evidence from mGluR7 Knockout Mice and siRNA-induced Knockdown in the Adult Mouse Brain. Review Articles [Details]
(2005)Use of RNAi in Target Validation for Neuropsychiatric Disorders.
Cryan J.F.; (2005) Use of RNAi in Target Validation for Neuropsychiatric Disorders. Review Articles [Details]
(2005)The use of genetically modified mice to understand the role of metabotropic glutamate 7 Receptors in Anxiety.
Cryan J.F.; (2005) The use of genetically modified mice to understand the role of metabotropic glutamate 7 Receptors in Anxiety. Review Articles [Details]
(2004)The Modified Rat Forced Swim Test:A tool to assess the role of monoamines in antidepressant action.
Cryan J.F.; (2004) The Modified Rat Forced Swim Test:A tool to assess the role of monoamines in antidepressant action. Review Articles [Details]
(2004)Targeting the GABAB receptor for the development of anxiolytic and antidepressants: Recent advances with novel pharmacological and genetic tools.
Cryan J.F.; (2004) Targeting the GABAB receptor for the development of anxiolytic and antidepressants: Recent advances with novel pharmacological and genetic tools. Review Articles [Details]
(2004)In search of a depressed mouse: models for studying depression-related behaviour in genetically modified mice.
Cryan J.F.; (2004) In search of a depressed mouse: models for studying depression-related behaviour in genetically modified mice. Review Articles [Details]
(2003)Murine models of depression: Utility for knockout and transgenic behavioral studies.
Cryan, J.F.; (2003) Murine models of depression: Utility for knockout and transgenic behavioral studies. Review Articles [Details]
(2000)Antidepressants associated with norepinephrine and serotonin pathways elicit distinct behaviors in a modified forced swim test.
Cryan, J.F., Page, M.E. and Lucki, I.; (2000) Antidepressants associated with norepinephrine and serotonin pathways elicit distinct behaviors in a modified forced swim test. Review Articles [Details]
(1997)Combining pindolol and paroxetine in an animal model of chronic antidepressant action - Can early onset of action be detected?.
Cryan J.F., McGrath, C., Leonard B.E. and Norman T.R; (1997) Combining pindolol and paroxetine in an animal model of chronic antidepressant action - Can early onset of action be detected?. Review Articles [Details]
(1996)The effects of the 5-HT1A agonist flesinoxan, in three paradigms for assessing antidepressant potential in the rat.
Cryan J.F., Redmond A.M., Kelly J.P. and Leonard B.E.; (1996) The effects of the 5-HT1A agonist flesinoxan, in three paradigms for assessing antidepressant potential in the rat. Review Articles [Details]

Honours and Awards

 YearTitleAwarding Body
2007National Institutes for Mental Health, NIH, USA. Distinguished Lecturer National Institutes for Mental Health, NIH, USA.
2006European College of Neuropsychopharmacology Fellowship Award European College of Neuropsychopharmacology
2006Wyeth Psychopharmacology Award of British Association of Psychopharmacology British Association of Psychopharmacology
2005Keynote speaker at New York Academy of the Sciences New York Academy of the Sciences
2005Young Scientist Award from Foundation of the European Behavioural Pharmacology Society Foundation of the European Behavioural Pharmacology Society
2005Novartis Neuroscience Recognition Award Novartis Pharma AG

Patents

 Patent NumberTitleInventorGranted
WO/2011/058535Probiotic bifidobacterium strain O'Mahony, L, Kiely B, Cryan JF, Dinan T, Murphy E.19-MAY-11
WO 2004/071152Use of S-10 hydroxy-10, 11-dihydro-carbamazepine for the treatment of anxiety and bipolar disorders Bilbe G, Cryan JF, Gentsch C, McAllister KH, Schmutz M, Vassout A01-JAN-04

Committees

 CommitteeFunctionFrom / To
External Examiner: University Birmingham, BMed Sci Degree 2008 /
External Examiner: Galway-Mayo Institute of Technology, Bachelor of Science (Honours) in Applied Biology and Biopharmaceutical Science 2008 / 2008
PhD Examiner Mr. Lucas Lecourtier, University of Bordeaux /
PhD Examiner Mr Danny Allen, Genetics Dept., Trinity College Dublin /
PhD Examiner Mr. Lawrence Tam, Genetics Dept., Trinity College Dublin /
Quality Review: NUI Galway, BSc Biotechnology Programme /

Employment

 EmployerPositionFrom / To
School of Pharmacy, University College Cork Senior Lecturer/Principal Investigator01-JUL-06 /
University College Cork Lecturer01-JAN-05 / 31-DEC-06
Novartis Institutes for BioMedical Research LabHead Behavioural Pharmacology01-JAN-02 / 31-DEC-05
The Scripps Research Institute Senior Postdoctoral Fellow01-JAN-01 / 31-DEC-01

Education

 YearInstituionQualificationSubject
1995NUI Galway BSc Hons, (NUI,Galway)Biochemistry
1998NUI Galway PHDPharmacology

Consultancy

 ClientDescription
National Institutes for Drug Abuse (NIDA): Review and Evaluation of NIDA Targets for Potential NIH Roadmap Library Screening

Reviews

 JournalRole
Proceedings Of The National Academy Of Science Usa Referee
Science Referee
Frontiers In Pharmacology Editor
Science Referee
Plos Biology Referee
Neuropharmacology Editor
Psychopharmacology Editor
Brain Research Member of Editorial Board
Behavioural Pharmacology Member of Editorial Board
Neuroscience And Biobehavioral Reviews Member of Editorial Board
Behavioural Brain Research Referee
Behavior Genetics Referee
Behavioural Pharmacology Referee
Brain Research Referee
British Journal Of Pharmacology Editor
European Journal Of Pharmacology Referee
Experimental Brain Research Referee
Genome Research Referee
Human Psychopharmacology Referee
Human Molecular Genetics Referee
Neuropsychopharmacology Referee
Journal Of Neural Transmission Referee
Journal Of Neurochemistry Referee
Journal Of Neuroscience Referee
Journal Of Pharmacology And Experimental Therapeutics Referee
Journal Of Psychopharmacology Referee
Neuropharmacology Referee
Neuropsychopharmacology Referee
Neuroscience Referee
Neuroscience And Biobehavioral Reviews Referee
Pharmacogenomics Referee
Pharmacology Biochemistry And Behavior Referee
Proceedings Of The National Academy Of Sciences Of The United States Of America Referee
Psychiatry Research Referee
Psychopharmacology Referee
Psychoneuroendocrinology Referee
Stress And Health Referee
Synapse (New York, N.Y.) Referee
Trends In Pharmacological Sciences Referee

Kennedy Paul JohnDoctoral DegreeCo-SupervisedMcallan LiamDoctoral DegreeMoloney GerardDoctoral DegreeHassan Sheikh AhmadDoctoral DegreeCo-SupervisedFelice ValeriaDoctoral DegreeCo-SupervisedO Brien Fionn EdwardDoctoral DegreeCo-SupervisedLomasney Kevin WilliamDoctoral DegreeCo-SupervisedMc Carthy Triona MaireDoctoral DegreeCo-SupervisedMoloney RachelDoctoral DegreeCo-SupervisedGodinho Bruno Miguel Da CruzDoctoral DegreeCo-Supervised
 Term (ID))TitleLinkSubject
2014Neurobiology of Disease AN3013Neurobiology of Disease