Research Profile

Mary Cahill

Biography

Mary Cahill graduated from UCC in 1986. Having completed two years training in CUH she took up a training post in haematology in Leicester and then in the Royal London. During her time in London she completed two years of full time research on platelets and platelet function in myeloproliferative disorders, culminating in an MD award from the University of London. 

She left London in 1997 to become the first (and only) Consultant Haematologist in the Mid Western Health Board providing service to Nenagh, Ennis and St John’s hospitals as well as the Mid Western Regional Hospital (now University Hospital Limerick-UHL). She gained funding from the HRB for the clinical trials unit in UHL. 

She moved to CUH in 2004 where she continued her interest in clinical trials. She has a major interest in teaching medical and science students in UCC. Since 2014, she has combined her full-time clinical post with ongoing collaborative research, focusing on autophagy in leukaemia with her colleague Dr Sharon McKenna in CCRC. Drs Cahill and McKenna have co-supervised two medical doctors carrying out research and both are likely to be future clinician scientist leaders in haematology in the future. Dr Cahill has supervised three other PhD students and many masters students registered in UCC, Coleraine and CIT. 

Prof Cahill has research links with numerous departments including, Pharmacy, Biochemistry, CRF, HRB-Clinical trials unit, NCRI and BCNI. She is currently involved in a large study on the diagnosis of pre-myeloma and myeloma in collaboration with Epidemiology and Public Health in UCC, thereby providing further links between CCRC and other UCC Departments. 

In 2015, she was awarded an SFI/ICS grant, in collaboration with colleagues in NUIG and TCD, to establish an all Ireland phase one clinical trials network firmly rooted in National Cancer Registry enhanced data collection and with additional funded enhanced bio-banking for blood cancers. This initiative will allow for further blood cancer-related research to be rooted in CCRC with enhanced opportunities for national collaboration with NUIG and TCD.

Publications

Book Chapters

 YearPublication
(2013)'“Thrombocytopenia –perils and pitfalls”'
Cahill MR (2013) '“Thrombocytopenia –perils and pitfalls”' In: Learning Clinical Skils; peirls pitfalls ans tips for the OSCE. Nova: Nova Science Publishers. [Details]

Peer Reviewed Journals

 YearPublication
(2018)'The potential for clinical translation of antibody-targeted nanoparticles in the treatment of acute myeloid leukaemia'
Guo J;Luan X;Cong Z;Sun Y;Wang L;McKenna SL;Cahill MR;O'Driscoll CM; (2018) 'The potential for clinical translation of antibody-targeted nanoparticles in the treatment of acute myeloid leukaemia'. Journal Of Controlled Release, 286 [DOI] [Details]
(2017)'Antibody-Targeted Cyclodextrin-Based Nanoparticles for siRNA Delivery in the Treatment of Acute Myeloid Leukemia: Physicochemical Characteristics, in Vitro Mechanistic Studies, and ex Vivo Patient Derived Therapeutic Efficacy'
Guo J;Russell EG;Darcy R;Cotter TG;McKenna SL;Cahill MR;O'Driscoll CM; (2017) 'Antibody-Targeted Cyclodextrin-Based Nanoparticles for siRNA Delivery in the Treatment of Acute Myeloid Leukemia: Physicochemical Characteristics, in Vitro Mechanistic Studies, and ex Vivo Patient Derived Therapeutic Efficacy'. Molecular Pharmaceutics, 14 (3) [DOI] [Details]
(2017)'Haemophagocytic lymphohistiocytosis presenting as HELLP syndrome: a diagnostic and therapeutic challenge'
Kerley RN;Kelly RM;Cahill MR;Kenny LC; (2017) 'Haemophagocytic lymphohistiocytosis presenting as HELLP syndrome: a diagnostic and therapeutic challenge'. BMJ case reports, 2017 [DOI] [Details]
(2017)'Risk adjusted therapy in chronic lymphocytic leukemia: a phase II cancer trials Ireland (CTRIAL-IE [ICORG 07-01]) study of fludarabine, cyclophosphamide, and rituximab therapy evaluating response adapted, abbreviated frontline therapy with FCR in non-del(17p) CLL'
Appleby N;O'Brien D;Quinn FM;Smyth L;Kelly J;Parker I;Scott K;Cahill MR;Crotty G;Enright H;Hennessy B;Hodgson A;Leahy M;O'Leary H;O'Dwyer M;Hayat A;Vandenberghe EA; (2017) 'Risk adjusted therapy in chronic lymphocytic leukemia: a phase II cancer trials Ireland (CTRIAL-IE [ICORG 07-01]) study of fludarabine, cyclophosphamide, and rituximab therapy evaluating response adapted, abbreviated frontline therapy with FCR in non-del(17p) CLL'. Leukemia & Lymphoma, [DOI] [Details]
(2017)'Physician and practice characteristics associated with immunoglobulin test ordering'
Cadogan SL;Browne JP;Bradley CP;Fitzgerald AP;Cahill MR; (2017) 'Physician and practice characteristics associated with immunoglobulin test ordering'. Family Practice, [DOI] [Details]
(2016)'The presence of C/EBP alpha and its degradation are both required for TRIB2-mediated leukaemia'
O'Connor, C,Lohan, F,Campos, J,Ohlsson, E,Salome, M,Forde, C,Artschwager, R,Liskamp, RM,Cahill, MR,Kiely, PA,Porse, B,Keeshan, K (2016) 'The presence of C/EBP alpha and its degradation are both required for TRIB2-mediated leukaemia'. Oncogene, 35 :5272-5281 [DOI] [Details]
(2016)'RNA interference for multiple myeloma therapy: targeting signal transduction pathways'
Guo J;McKenna SL;O'Dwyer ME;Cahill MR;O'Driscoll CM; (2016) 'RNA interference for multiple myeloma therapy: targeting signal transduction pathways'. Expert Opinion on Therapeutic Targets, 20 (1) [DOI] [Details]
(2016)'Ionizing radiation exposure as a result of diagnostic imaging in patients with lymphoma'
Crowley, MP;O'Neill, SB;Kevane, B;O'Neill, DC;Eustace, JA;Cahill, MR;Bird, B;Maher, MM;O'Regan, K;O'Shea, D (2016) 'Ionizing radiation exposure as a result of diagnostic imaging in patients with lymphoma'. Clinical & Translational Oncology, 18 :533-536 [DOI] [Details]
(2016)'General practitioner views on the determinants of test ordering: a theory-based qualitative approach to the development of an intervention to improve immunoglobulin requests in primary care'
Cadogan, SL;McHugh, SM;Bradley, CP;Browne, JP;Cahill, MR (2016) 'General practitioner views on the determinants of test ordering: a theory-based qualitative approach to the development of an intervention to improve immunoglobulin requests in primary care'. Implementation Science, 11 [DOI] [Details]
(2016)'General practitioner views on the determinants of test ordering: a theory-based qualitative approach to the development of an intervention to improve immunoglobulin requests in primary care'
Cadogan, S; McHugh, SM; Cahill, MR; Browne, JP; Bradley, C. (2016) 'General practitioner views on the determinants of test ordering: a theory-based qualitative approach to the development of an intervention to improve immunoglobulin requests in primary care'. Implementation Science, 11 [Details]
(2016)'CALR mutation profile in Irish patients with myeloproliferative neoplasms'
Haslam, Karl; Conneally, Eibhlin; Flynn, Catherine M.; Cahill, Mary R.; Gilligan, Oonagh; O’Shea, Derville; Langabeer, Stephen E. (2016) 'CALR mutation profile in Irish patients with myeloproliferative neoplasms'. Hematology/Oncology And Stem Cell Therapy, 9 (3):112-115 [DOI] [CORA Link] [Details]
(2016)'A novel 33-Gene targeted resequencing panel provides accurate, clinical-grade diagnosis and improves patient management for rare inherited anaemias'
Roy, NBA;Wilson, EA;Henderson, S;Wray, K;Babbs, C;Okoli, S;Atoyebi, W;Mixon, A;Cahill, MR;Carey, P;Cullis, J;Curtin, J;Dreau, H;Ferguson, DJP;Gibson, B;Hall, G;Mason, J;Morgan, M;Proven, M;Qureshi, A;Garcia, JS;Sirachainan, N;Teo, J;Tedgard, U;Higgs, D;Roberts, D;Roberts, I;Schuh, A (2016) 'A novel 33-Gene targeted resequencing panel provides accurate, clinical-grade diagnosis and improves patient management for rare inherited anaemias'. British Journal of Haematology, 175 :318-330 [DOI] [Details]
(2015)'The effectiveness of interventions to improve laboratory requesting patterns among primary care physicians: a systematic review'
Cadogan SL;Browne JP;Bradley CP;Cahill MR; (2015) 'The effectiveness of interventions to improve laboratory requesting patterns among primary care physicians: a systematic review'. Implementation Science : Is, 10 [DOI] [Details]
(2015)'Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation'
Orfali, N;O'Donovan, TR;Nyhan, MJ;Britschgi, A;Tschan, MP;Cahill, MR;Mongan, NP;Gudas, LJ;McKenna, SL (2015) 'Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation'. Experimental Hematology, 43 :781-793 [DOI] [Details]
(2015)'Smoking as an independent risk factor for macrocytosis in middle-aged adults: a population-based observational study'
O'Reilly MA, Millar SR, Buckley CM, Harrington JM, Perry IJ, Cahill MR (2015) 'Smoking as an independent risk factor for macrocytosis in middle-aged adults: a population-based observational study'. American journal of hematology, 90 (9) [DOI] [Details]
(2015)'The effectiveness of interventions to improve laboratory requesting patterns among primary care physicians: a systematic review'
Cadogan, S; Browne, JP; Bradley, C; Cahill, MR. (2015) 'The effectiveness of interventions to improve laboratory requesting patterns among primary care physicians: a systematic review'. Implementation Science, 10 [Details]
(2014)'Biomimetic nanoparticles for siRNA delivery in the treatment of leukaemia'
Guo J;Cahill MR;McKenna SL;O'Driscoll CM; (2014) 'Biomimetic nanoparticles for siRNA delivery in the treatment of leukaemia'. Biotechnology Advances, 32 (8) [DOI] [Details]
(2014)'Retinoid receptor signaling and autophagy in acute promyelocytic leukemia'
Orfali N;McKenna SL;Cahill MR;Gudas LJ;Mongan NP; (2014) 'Retinoid receptor signaling and autophagy in acute promyelocytic leukemia'. Experimental Cell Research, 324 (1) [DOI] [Details]
(2014)'Biomimetic nanoparticles for siRNA delivery in the treatment of leukaemia'
Guo J, Cahill MR, McKenna SL, O’Driscoll CM. (2014) 'Biomimetic nanoparticles for siRNA delivery in the treatment of leukaemia'. Biotechnology Advances, [DOI] [Details]
(2014)'Regulation of Trib2 by an E2F1-C/EBP alpha feedback loop in AML cell proliferation'
Rishi, L,Hannon, M,Salome, M,Hasemann, M,Frank, AK,Campos, J,Timoney, J,O'Connor, C,Cahill, MR,Porse, B,Keeshan, K (2014) 'Regulation of Trib2 by an E2F1-C/EBP alpha feedback loop in AML cell proliferation'. Blood, 123 :2389-2400 [DOI] [Details]
(2013)'Induction of autophagy by Imatinib sequesters Bcr-Abl in autophagosomes and down-regulates Bcr-Abl protein'
Elzinga, BM,Nyhan, MJ,Crowley, LC,O'Donovan, TR,Cahill, MR,McKenna, SL (2013) 'Induction of autophagy by Imatinib sequesters Bcr-Abl in autophagosomes and down-regulates Bcr-Abl protein'. American journal of hematology, 88 :455-462 [DOI] [Details]
(2013)'Haematinic Deficiency and Macrocytosis in Middle-Aged and Older Adults'
McNamee, T,Hyland, T,Harrington, J,Cadogan, S,Honari, B,Perera, K,Fitzgerald, AP,Perry, IJ,Cahill, MR (2013) 'Haematinic Deficiency and Macrocytosis in Middle-Aged and Older Adults'. Plos One, 8 [DOI] [Details]
(2013)'A multi-centre retrospective study of rituximab use in the treatment of relapsed or resistant warm autoimmune haemolytic anaemia'
Maung SW, Leahy M, O'Leary HM, Khan I, Cahill MR, Gilligan O, Murphy P, McPherson S, Jackson F, Ryan M, Hennessy B, McHugh J, Goodyer M, Bacon L, O'Gorman P, Nee A, O'Dwyer M, Enright H, Saunders J, O'Keeffe D (2013) 'A multi-centre retrospective study of rituximab use in the treatment of relapsed or resistant warm autoimmune haemolytic anaemia'. British Journal of Haematology, 163 (1):118-122 [DOI] [Details]
(2013)'A multi-centre retrospective study of rituximab use in the treatment of relapsed or resistant warm autoimmune haemolytic anaemia'
Maung, SW,Leahy, M,O'Leary, HM,Khan, I,Cahill, MR,Gilligan, O,Murphy, P,McPherson, S,Jackson, F,Ryan, M,Hennessy, B,McHugh, J,Goodyer, M,Bacon, L,O'Gorman, P,Nee, A,O'Dwyer, M,Enright, H,Saunders, J,O'Keeffe, D (2013) 'A multi-centre retrospective study of rituximab use in the treatment of relapsed or resistant warm autoimmune haemolytic anaemia'. British Journal of Haematology, 163 :118-122 [DOI] [Details]
(2010)'Phase I/II safety study of transfusion of prion-filtered red cell concentrates in transfusion-dependent patients'
Cahill, MR;Murphy, T;Khan, M;Fagan, J;Murphy, WG (2010) 'Phase I/II safety study of transfusion of prion-filtered red cell concentrates in transfusion-dependent patients'. Vox sanguinis, 99 :174-176 [DOI] [Details]
(2009)'Can mean platelet component be used as an index of platelet activity in stable coronary artery disease?'
Cooke, J;Murphy, T;McFadden, E;O'Reilly, M;Cahill, MR (2009) 'Can mean platelet component be used as an index of platelet activity in stable coronary artery disease?'. Hematology, 14 :111-114 [DOI] [Details]
(2006)'Writing to patients: a randomised controlled trial'
O'Reilly, M;Cahill, MR;Perry, IJ (2006) 'Writing to patients: a randomised controlled trial'. Clinical Medicine, 6 :178-182 [Details]
(2005)'The issue of Anti-D: An integrated seamless approach from recognition of need to bedside administration'
Ryan, MJ;Joyce, S;O'Brien, N;Lynch, E;Burke, G;Cahill, MR (2005) 'The issue of Anti-D: An integrated seamless approach from recognition of need to bedside administration'. Irish Journal of Medicine, 174 :58-63 [Details]
(2005)'Duration of increased bleeding tendency after cessation of aspirin therapy'
Cahill, RA;McGreal, GT;Crowe, BH;Ryan, DA;Manning, BJ;Cahill, MR;Redmond, HP (2005) 'Duration of increased bleeding tendency after cessation of aspirin therapy'. Journal of The American College of Surgeons, 200 :564-573 [DOI] [Details]
(2005)'Duration of increased bleeding tendency after cessation of aspirin therapy'
Cahill, R. A.,McGreal, G. T.,Crowe, B. H.,Ryan, D. A.,Manning, B. J.,Cahill, M. R.,Redmond, H. P.; (2005) 'Duration of increased bleeding tendency after cessation of aspirin therapy'. Journal of the American College of Surgeons, 200 (44):564-573564   [Details]
(2013)'Induction of autophagy by Imatinib sequesters Bcr-Abl in autophagosomes and down-regulates Bcr-Abl protein'
Elzinga BM, Nyhan MJ, Crowley LC, O'Donovan TR, Cahill MR, McKenna SL (2013) 'Induction of autophagy by Imatinib sequesters Bcr-Abl in autophagosomes and down-regulates Bcr-Abl protein'. American journal of hematology, 88 (6):455-462 [DOI] [Details]
(2010)'Sustained clinical remission despite suboptimal molecular response to imatinib in e1a2 BCR-ABL chronic myeloid leukemia'
Langabeer SE, Crampe M, Haslam K, Kelly J, Cahill MR; (2010) 'Sustained clinical remission despite suboptimal molecular response to imatinib in e1a2 BCR-ABL chronic myeloid leukemia'. Leukemia Research, 34 (7):1-7 [DOI] [Details]
(2010)'Phase I/II safety study of transfusion of prion-filtered red cell concentrates in transfusion-dependent patients'
Cahill MR, Murphy T, Khan M, Fagan J, Murphy WG (2010) 'Phase I/II safety study of transfusion of prion-filtered red cell concentrates in transfusion-dependent patients'. Vox sanguinis, 99 (2):174-176 [DOI] [Details]
(2009)'Can mean platelet component be used as an index of platelet activity in stable coronary artery disease?'
Cooke J, Murphy T, McFadden E, O'Reilly M, Cahill MR; (2009) 'Can mean platelet component be used as an index of platelet activity in stable coronary artery disease?'. Hematology (Amsterdam, Netherlands), 14 (2):111-114 [DOI] [Details]
(2007)'Warfarin prevalence, indications for use and haemorrhagic events'
Ouirke, W.;Cahill, M.R.;Perera, K.;Sargent, J.;Conway, J. (2007) 'Warfarin prevalence, indications for use and haemorrhagic events'. Irish Medical Journal, 100 (3):402-404 [CORA Link] [Details]
(2006)'Writing to patients: a randomised controlled trial'
O'Reilly M.; Cahill MR; Perry IJ; (2006) 'Writing to patients: a randomised controlled trial'. Clinical Medicine, 6 (2):178-182   [CORA Link] [Details]
(2005)'Autologous stem cell transplantation in myeloma: the St James's Hospital experience, 1997-2003. Ir J Med Sci. 2005 Apr-Jun;174(2):26-32'
Hayden PJ, O'Driscoll A, Gardiner N, Swords R, Sargent J, Ainle FN, Fortune A, Murphy PT, Leahy M, Jackson F, Ryan M, Hennessy B, Cahill M, Crotty GM, Enright H, Conneally E, Vandenberghe E, McCann SR, Browne PV.; (2005) 'Autologous stem cell transplantation in myeloma: the St James's Hospital experience, 1997-2003. Ir J Med Sci. 2005 Apr-Jun;174(2):26-32'. Irish Journal of Medical Science, 174 (2):26-32 [Details]
(2005)'Detection of Aspirin Resistance by PFA-100: Prevalence and Aspirin Compliance in Patients with Chronic Stable Angina'
Crowe B, Abbas S, Meany B, de Haan J, Cahill MR.; (2005) 'Detection of Aspirin Resistance by PFA-100: Prevalence and Aspirin Compliance in Patients with Chronic Stable Angina'. Seminars In Thrombosis and Hemostasis, 31 (4):420-425 [Details]
(2005)'Writing to patients: 'putting the patient in the picture''
Reilly MO, Cahill M, Perry IJ.; (2005) 'Writing to patients: 'putting the patient in the picture''. Irish Medical Journal, 98 (2):58-60 [CORA Link] [Details]
(2005)'The issue of Anti-D: An integrated seamless approach from recognition of need to bedside administration'
Ryan, MJ,Joyce, S,O'Brien, N,Lynch, E,Burke, G,Cahill, MR (2005) 'The issue of Anti-D: An integrated seamless approach from recognition of need to bedside administration'. Irish Journal of Medical Science, 174 :58-63 [Details]
(2004)'Fatal thrombocytopaenia temporally related to the administration of alemtuzumab (MabCampath) for refractory CLL despite early discontinuation of therapy'
Haider I, Cahill M.; (2004) 'Fatal thrombocytopaenia temporally related to the administration of alemtuzumab (MabCampath) for refractory CLL despite early discontinuation of therapy'. Hematology, 9 (5-6):409-411 [Details]
(2004)'Successful intra-articular chemotherapy for relapsed acute myeloid leukaemia infiltrating the knee joint. '
Ramadan K, Cahill M.; (2004) 'Successful intra-articular chemotherapy for relapsed acute myeloid leukaemia infiltrating the knee joint. '. British Journal of Haematology, 124 (3):258-258 [Details]
(2003)'Haemovigilance is associated with decreased use and improved appropriateness of blood transfusion'
Cahill, M. R. and Joyce, S. and O'Brien, N. and Casey, M. (2003) 'Haemovigilance is associated with decreased use and improved appropriateness of blood transfusion'. Vox Sanguinis, 85 (2):121-122   [DOI] [Details]
(2003)'Cerebral venous sinus thrombosis precipitated by Graves' disease and Factor V Leiden mutation'
Molloy E, Cahill M, O'Hare JA.; (2003) 'Cerebral venous sinus thrombosis precipitated by Graves' disease and Factor V Leiden mutation'. Irish Medical Journal, 96 (2):46-47 [Details]
(2001)'The effects of ropivacaine hydrochloride on platelet function: an assessment using the platelet function analyser (PFA-100)'
Porter J, Crowe B, Cahill M, Shorten G.; (2001) 'The effects of ropivacaine hydrochloride on platelet function: an assessment using the platelet function analyser (PFA-100)'. Anesthesia, 56 (1):15-18 [Details]
(2001)'P-selectin and glycoprotein 53 expression in myeloproliferative disorders'
Cahill MR.; (2001) 'P-selectin and glycoprotein 53 expression in myeloproliferative disorders'. British Journal of Haematology, 112 (1):253-253 [Details]
(1998)'Adhesion molecules in clinical medicine'
Cavenagh JD, Cahill MR, Kelsey SM (1998) 'Adhesion molecules in clinical medicine'. Critical reviews in clinical laboratory sciences, 35 (5):415-459 [DOI] [Details]
(1998)'Protein A immunoadsorption in chronic refractory ITP reverses increased platelet activation but fails to achieve sustained clinical benefit'
Cahill MR, Macey MG, Cavenagh JD, Newland AC (1998) 'Protein A immunoadsorption in chronic refractory ITP reverses increased platelet activation but fails to achieve sustained clinical benefit'. British Journal of Haematology, 100 (2):358-364 [Details]
(1998)'The rational use of platelet transfusions in children'
Cahill MR, Lilleyman JS.; (1998) 'The rational use of platelet transfusions in children'. Seminars In Thrombosis and Hemostasis, 24 (6):567-575 [Details]
(1997)'Clinical significance of platelet size in inflammatory bowel disease?'
Collins CE, Cahill MR, Rampton DS (1997) 'Clinical significance of platelet size in inflammatory bowel disease?'. Thrombosis and Haemostasis, 77 (1):218-219 [Details]
(1997)'Inflammation, aspirin, and the risk of cardiovascular disease'
Cahill MR; Perry IJ.; (1997) 'Inflammation, aspirin, and the risk of cardiovascular disease'. New England Journal of Medicine, 337 (6):422-423   [DOI] [CORA Link] [Details]
(1997)'Is it refractory idiopathic thrombocytopenic purpura?'
Cahill MR, Newland AC.; (1997) 'Is it refractory idiopathic thrombocytopenic purpura?'. Lancet, 349 (9058):1066-* [Details]
(1997)'Haemophilia'
Cahill Mary R.; Colvin BT; (1997) 'Haemophilia'. Postgraduate Medical Journal, 73 (858):201-206 [CORA Link] [Details]
(1996)'Platelet surface activation antigen expression at baseline and during elective angioplasty in patients with mild to moderate coronary artery disease'
Cahill MR, Macey MG, Dawson JR, Newland AC.; (1996) 'Platelet surface activation antigen expression at baseline and during elective angioplasty in patients with mild to moderate coronary artery disease'. Blood Coagulation and Fibrinolysis, 7 (2):165-168 [Details]
(1996)'Correlation of GP53 and P-selectin expression in myeloproliferative disorders and normal controls. '
Cahill MR, Macey MG, Newland AC.; (1996) 'Correlation of GP53 and P-selectin expression in myeloproliferative disorders and normal controls. '. Blood Coagulation and Fibrinolysis, 7 (2):169-171 [Details]
(1995)'Treatment of acute myeloid leukaemia in pregnancy'
Cavenagh JD, Richardson DS, Cahill MR, Bernard T, Kelsey SM, Newland AC (1995) 'Treatment of acute myeloid leukaemia in pregnancy'. Lancet, 346 (8972):441-442 [Details]
(1994)'Prevention of restenosis after angioplasty'
Cahill MR, Macey MG, Dawson JR, Newland AC (1994) 'Prevention of restenosis after angioplasty'. Lancet, 343 (8909) [Details]
(1994)'Effect of fixation on quantification of the expression of leucocyte function-associated surface antigens'
McCarthy DA, Macey MG, Cahill MR, Newland AC (1994) 'Effect of fixation on quantification of the expression of leucocyte function-associated surface antigens'. Cytometry, 17 (1):39-49 [DOI] [Details]
(1994)'Platelets circulate in an activated state in inflammatory bowel disease'
Collins CE, Cahill MR, Newland AC, Rampton DS (1994) 'Platelets circulate in an activated state in inflammatory bowel disease'. Gastroenterology, 106 (4):840-845 [Details]
(1993)'Clubbing in Crohn's disease'
Collins CE, Cahill MR, Rampton DS (1993) 'Clubbing in Crohn's disease'. BMJ (Clinical Research Ed.), 307 (6902) [Details]
(1993)'von Willebrand factor release and P-selectin expression is stimulated by thrombin and trypsin but not IL-1 in cultured human endothelial cells'
Collins PW, Macey MG, Cahill MR, Newland AC (1993) 'von Willebrand factor release and P-selectin expression is stimulated by thrombin and trypsin but not IL-1 in cultured human endothelial cells'. Thrombosis and Haemostasis, 70 (2):346-350 [Details]
(1993)'Platelet activation in coronary artery disease'
Cahill MR, Newland AC (1993) 'Platelet activation in coronary artery disease'. British journal of biomedical science, 50 (3):221-234 [Details]
(1993)'Fixation with formaldehyde induces expression of activation dependent platelet membrane glycoproteins, P selectin (CD62) and GP53 (CD63)'
Cahill MR, Macey MG, Newland AC (1993) 'Fixation with formaldehyde induces expression of activation dependent platelet membrane glycoproteins, P selectin (CD62) and GP53 (CD63)'. British Journal of Haematology, 84 (3):527-529 [Details]
(1993)'Protein-A-column plasma immunoadsorption in refractory autoimmune neutropenia and thrombocytopenia'
Bernard T, Kelsey SM, Macey MG, Cahill MR, Howe T, Newland AC (1993) 'Protein-A-column plasma immunoadsorption in refractory autoimmune neutropenia and thrombocytopenia'. Lancet, 341 (8861):1657-1658 [Details]
(1991)'Aplastic anaemia in systemic lupus erythematosus: a cellular immune mechanism?'
Roffe C, Cahill MR, Samanta A, Bricknell S, Durrant ST (1991) 'Aplastic anaemia in systemic lupus erythematosus: a cellular immune mechanism?'. The Journal of Rheumatology, 30 (4):301-304 [Details]
(1986)'The measles immunisation programme--early results from Cork'
Cahill, M.,McKiernan, J. (1986) 'The measles immunisation programme--early results from Cork'. Irish Medical Journal, 79 (7)   [Details]

Conference Publications

 YearPublication
(2013)British Society for HaematologyPoster presentation at BSH Liverpool April 2013 (Publication in British Journal Haematology suppl)
JM O’ Sullivan, S Prendeville, TJ Browne, K Feeley, C Duggan, MR Cahill (2013) Review of bone marrow examination quality in a university teaching hospital and referring peripheral hospitals British Society for HaematologyPoster presentation at BSH Liverpool April 2013 (Publication in British Journal Haematology suppl) [Details]

Abstract

 YearPublication
(2018)WEEKLY CYBORD-DARA IS A SAFE AND EFFECTIVE UPFRONT TREATMENT FOR NEWLY DIAGNOSED MULTIPLE MYELOMA. PRELIMINARY RESULTS OF THE EARLY-PHASE 16-BCNI-001/CTRIAL-IE (ICORG) 16-02 STUDY.
McEllistrim, C;Cahill, MR;Murphy, P;Mykytiv, V;Quinn, J;Bray, A;Walsh, J;Lenihan, E;Kenny, T;Hirakata,;Parker, I;Hernando, A;O'Dwyer, M (2018) WEEKLY CYBORD-DARA IS A SAFE AND EFFECTIVE UPFRONT TREATMENT FOR NEWLY DIAGNOSED MULTIPLE MYELOMA. PRELIMINARY RESULTS OF THE EARLY-PHASE 16-BCNI-001/CTRIAL-IE (ICORG) 16-02 STUDY. PAVIA: Abstract [Details]
(2016)A Prospective Audit of Haematinic Requests from General Practice in Cork University Hospital (CUH) Haematology Laboratory.
O'Meara, M;Cadogan, S;O'Reilly, M;Minihane, D;Cahill, MR (2016) A Prospective Audit of Haematinic Requests from General Practice in Cork University Hospital (CUH) Haematology Laboratory. LONDON: Abstract [Details]
(2015)ANTIBODY-TARGETED CYCLODEXTRIN NANOPARTICLES DELIVER SIRNA AND ACHIEVE THERAPEUTIC GENE SILENCING IN BLOOD FROM ACUTE MYELOID LEUKAEMIA (AML) PATIENTS.
Guo, J;Fitzgerald, KA;Russell, EG;Darcy, R;Cotter, TG;McKenna, SL;Cahill, MR;Driscoll, CMO (2015) ANTIBODY-TARGETED CYCLODEXTRIN NANOPARTICLES DELIVER SIRNA AND ACHIEVE THERAPEUTIC GENE SILENCING IN BLOOD FROM ACUTE MYELOID LEUKAEMIA (AML) PATIENTS. PAVIA: Abstract [Details]
(2015)ANTIBODY-TARGETED CYCLODEXTRIN NANOPARTICLES DELIVER SIRNA AND ACHIEVE THERAPEUTIC GENE SILENCING IN BLOOD FROM ACUTE MYELOID LEUKAEMIA (AML) PATIENTS.
Guo, J,Fitzgerald, KA,Russell, EG,Darcy, R,Cotter, TG,McKenna, SL,Cahill, MR,Driscoll, CMO (2015) ANTIBODY-TARGETED CYCLODEXTRIN NANOPARTICLES DELIVER SIRNA AND ACHIEVE THERAPEUTIC GENE SILENCING IN BLOOD FROM ACUTE MYELOID LEUKAEMIA (AML) PATIENTS. Abstract [Details]
(2014)ATRA-Induced Activation of the Autophagy Regulator Tfeb Regulates Myeloid Differentiation in Acute Promyelocytic Leukemia.
Orfali, NM;Mongan, NP;Cahill, MR;McKenna, SL;Gudas, LJ (2014) ATRA-Induced Activation of the Autophagy Regulator Tfeb Regulates Myeloid Differentiation in Acute Promyelocytic Leukemia. WASHINGTON: Abstract [Details]
(2014)THE IMPACT OF LIFESTYLE FACTORS ON RAISED RED CELL MEAN CORPUSCULAR VOLUME IN AN IRISH POPULATION-NOT JUST A 'HAEMATOLOGY' PROBLEM.
O'Reilly, MA;Harrington, JM;Buckley, CM;Perry, IJ;Cahill, MR (2014) THE IMPACT OF LIFESTYLE FACTORS ON RAISED RED CELL MEAN CORPUSCULAR VOLUME IN AN IRISH POPULATION-NOT JUST A 'HAEMATOLOGY' PROBLEM. PAVIA: Abstract [Details]
(2014)A REVIEW OF HIGH GRADE NON-HODGKIN LYMPHOMA CARE IN A UNIVERSITY HOSPITAL GROUP IN IRELAND.
Crowley, MP;Crotty, R;Cahill, MR;Murphy, CG;O'Keeffe, J;Bird, BR (2014) A REVIEW OF HIGH GRADE NON-HODGKIN LYMPHOMA CARE IN A UNIVERSITY HOSPITAL GROUP IN IRELAND. PAVIA: Abstract [Details]
(2014)A REVIEW OF HIGH GRADE NON-HODGKIN LYMPHOMA CARE IN A UNIVERSITY HOSPITAL GROUP IN IRELAND.
Crowley, MP,Crotty, R,Cahill, MR,Murphy, CG,O'Keeffe, J,Bird, BR (2014) A REVIEW OF HIGH GRADE NON-HODGKIN LYMPHOMA CARE IN A UNIVERSITY HOSPITAL GROUP IN IRELAND. Abstract [Details]
(2013)Review of bone marrow examination quality in a university teaching hospital and referring peripheral hospitals.
O'Sullivan, JM;Prendeville, S;Browne, TJ;Feeley, K;Duggan, C;Cahill, MR (2013) Review of bone marrow examination quality in a university teaching hospital and referring peripheral hospitals. HOBOKEN: Abstract [Details]
(2013)A prospective audit of haematinic requests from general practice in Cork University Hospital (CUH) Haematology Laboratory.
O'Meara, M;Cadogan, S;O'Reilly, M;Minihane, D;Cahill, MR (2013) A prospective audit of haematinic requests from general practice in Cork University Hospital (CUH) Haematology Laboratory. HOBOKEN: Abstract [Details]
(2013)A prospective audit of haematinic requests from general practice in Cork University Hospital (CUH) Haematology Laboratory.
O'Meara, M,Cadogan, S,O'Reilly, M,Minihane, D,Cahill, MR (2013) A prospective audit of haematinic requests from general practice in Cork University Hospital (CUH) Haematology Laboratory. Abstract [Details]
(2013)Review of bone marrow examination quality in a university teaching hospital and referring peripheral hospitals.
O'Sullivan, JM,Prendeville, S,Browne, TJ,Feeley, K,Duggan, C,Cahill, MR (2013) Review of bone marrow examination quality in a university teaching hospital and referring peripheral hospitals. Abstract [Details]
(2012)Autophagy As a Target for Differentiation Therapy in Acute Myeloid Leukemia.
Orfali, NM;O'Donovan, T;Nyhan, M;Mongan, NP;Gudas, LJ;Cahill, MR;McKenna, S (2012) Autophagy As a Target for Differentiation Therapy in Acute Myeloid Leukemia. WASHINGTON: Abstract [Details]
(2012)Minimal Residual Disease Stratification in Fludarabine Ccyclophosphamide Rituximab (FCR) Therapy in Chronic Lymphocytic Leukaemia (CLL.
Hayat, A,O'Brien, D,Quinn, F,Keane, F,Parker, I,Kelly, J,Wieczorkowska, M,Crotty, G,Leahy, M,Enright, H,Hennessy, B,Cahill, M,Vandenberghe, EA (2012) Minimal Residual Disease Stratification in Fludarabine Ccyclophosphamide Rituximab (FCR) Therapy in Chronic Lymphocytic Leukaemia (CLL. Abstract [Details]
(2011)Aspirin treated subjects show attenuated electron microscopic evidence of platelet activation and a parallel attenuation in thrombin stimulated platelet activation antigens.
Cahill, MR;Macey, M;Newland, AC (2011) Aspirin treated subjects show attenuated electron microscopic evidence of platelet activation and a parallel attenuation in thrombin stimulated platelet activation antigens. HOBOKEN: Abstract [Details]
(2011)Aspirin treated subjects show attenuated electron microscopic evidence of platelet activation and a parallel attenuation in thrombin stimulated platelet activation antigens.
Cahill, MR,Macey, M,Newland, AC (2011) Aspirin treated subjects show attenuated electron microscopic evidence of platelet activation and a parallel attenuation in thrombin stimulated platelet activation antigens. Abstract [Details]
(2010)Molecular responses to tyrosine kinase inhibitors in rare, variant e1a2, e6a2 and e19a2 BCR-ABL chronic myeloid leukaemia.
Langabeer, SE;Crampe, M;McCarron, SL;Haslam, K;Connaghan, G;Perera, K;Cahill, MR;Conneally, E (2010) Molecular responses to tyrosine kinase inhibitors in rare, variant e1a2, e6a2 and e19a2 BCR-ABL chronic myeloid leukaemia. MALDEN: Abstract [Details]
(2010)DURATION OF ANTI-HAEMOSTATIC EFFECTS FOLLOWING CESSATION OF CLOPIDOGREL THERAPY AND DUAL CLOPIDOGREL AND ASPIRIN THERAPY.
Cronin, PA;Quinn, EM;Killeen, SD;O'Brien, GC;Andrews, EJ;Cahill, MR;Redmond, HP;Fulton, GJ (2010) DURATION OF ANTI-HAEMOSTATIC EFFECTS FOLLOWING CESSATION OF CLOPIDOGREL THERAPY AND DUAL CLOPIDOGREL AND ASPIRIN THERAPY. LONDON: Abstract [Details]
(2008)A PHASE 1 CLINICAL TRIAL OF PRION-FILTERED RED CELL CONCENTRATES IN PATIENTS REQUIRING ALLOGENEIC BLOOD TRANSFUSION.
Cahill, MR;Murphy, TM;Fagan, J;Croxon, H;McGrath, S;Gilligan, O;Murphy, W (2008) A PHASE 1 CLINICAL TRIAL OF PRION-FILTERED RED CELL CONCENTRATES IN PATIENTS REQUIRING ALLOGENEIC BLOOD TRANSFUSION. PAVIA: Abstract [Details]
(2012)Autophagy As a Target for Differentiation Therapy in Acute Myeloid Leukemia.
Orfali, NM,O'Donovan, T,Nyhan, M,Mongan, NP,Gudas, LJ,Cahill, MR,McKenna, S (2012) Autophagy As a Target for Differentiation Therapy in Acute Myeloid Leukemia. Abstract [Details]
(2012)Induction of Autophagy by Imatinib Sequesters BCR-ABL in Autophagosomes and Reduces BCR-ABL Expression.
Nyhan, M,Elzinga, B,Crowley, L,O'Donovan, T,Orfali, N,O'Sullivan, GC,Cahill, M,McKenna, SL (2012) Induction of Autophagy by Imatinib Sequesters BCR-ABL in Autophagosomes and Reduces BCR-ABL Expression. Abstract [Details]
(2011)Multicentre Retrospective Analysis of Rituximab Use in the Treatment of Steroid Resistant Autoimmune Haemolytic Anaemia in Ireland.
Maung, SW,O'Keeffe, D,Leahy, M,O'Leary, HM,Khan, I,Cahill, M,Galligan, O,Murphy, P,Krawczyk, J,McPherson, S,Jackson, JF,Ryan, M,Hennessy, B,Burke, AC,Enright, H,McHugh, J (2011) Multicentre Retrospective Analysis of Rituximab Use in the Treatment of Steroid Resistant Autoimmune Haemolytic Anaemia in Ireland. Abstract [Details]
(2010)Molecular responses to tyrosine kinase inhibitors in rare, variant e1a2, e6a2 and e19a2 BCR-ABL chronic myeloid leukaemia.
Langabeer, SE,Crampe, M,McCarron, SL,Haslam, K,Connaghan, G,Perera, K,Cahill, MR,Conneally, E (2010) Molecular responses to tyrosine kinase inhibitors in rare, variant e1a2, e6a2 and e19a2 BCR-ABL chronic myeloid leukaemia. Abstract [Details]
(2010)DURATION OF ANTI-HAEMOSTATIC EFFECTS FOLLOWING CESSATION OF CLOPIDOGREL THERAPY AND DUAL CLOPIDOGREL AND ASPIRIN THERAPY.
Cronin, PA,Quinn, EM,Killeen, SD,O'Brien, GC,Andrews, EJ,Cahill, MR,Redmond, HP,Fulton, GJ (2010) DURATION OF ANTI-HAEMOSTATIC EFFECTS FOLLOWING CESSATION OF CLOPIDOGREL THERAPY AND DUAL CLOPIDOGREL AND ASPIRIN THERAPY. Abstract [Details]
(2008)A PHASE 1 CLINICAL TRIAL OF PRION-FILTERED RED CELL CONCENTRATES IN PATIENTS REQUIRING ALLOGENEIC BLOOD TRANSFUSION.
Cahill, MR,Murphy, TM,Fagan, J,Croxon, H,McGrath, S,Gilligan, O,Murphy, W (2008) A PHASE 1 CLINICAL TRIAL OF PRION-FILTERED RED CELL CONCENTRATES IN PATIENTS REQUIRING ALLOGENEIC BLOOD TRANSFUSION. Abstract [Details]
(1999)The effects of ropivacaine hydrochloride on platelet function.
Porter, JM,Crowe, B,Cahill, M,Shorten, GD (1999) The effects of ropivacaine hydrochloride on platelet function. Abstract [Details]

Other

 YearPublication
(2010)Sustained clinical remission despite suboptimal molecular response to imatinib in e1a2 BCR-ABL chronic myeloid leukemia.
Langabeer, SE,Crampe, M,Haslam, K,Kelly, J,Cahill, MR (2010) Sustained clinical remission despite suboptimal molecular response to imatinib in e1a2 BCR-ABL chronic myeloid leukemia. Other [DOI] [Details]
(2005)Detection of aspirin resistance by PFA-100: Prevalence and aspirin compliance in patients with chronic stable angina.
Crowe, B,Abbas, S,Meany, B,de Haan, J,Cahill, MR (2005) Detection of aspirin resistance by PFA-100: Prevalence and aspirin compliance in patients with chronic stable angina. Other [Details]
(1997)Inflammation, aspirin, and the risk of cardiovascular disease.
Cahill, MR,Perry, IJ (1997) Inflammation, aspirin, and the risk of cardiovascular disease. Other [Details]

Published Letters

 YearPublication
(2015)Smoking as an independent risk factor for macrocytosis in middle-aged adults: A population-based observational study.
O'Reilly, MA;Millar, SR;Buckley, CM;Harrington, JM;Perry, IJ;Cahill, MR (2015) Smoking as an independent risk factor for macrocytosis in middle-aged adults: A population-based observational study. HOBOKEN: Published Letters [DOI] [Details]
(2010)Sustained clinical remission despite suboptimal molecular response to imatinib in e1a2 BCR-ABL chronic myeloid leukemia.
Langabeer, SE;Crampe, M;Haslam, K;Kelly, J;Cahill, MR (2010) Sustained clinical remission despite suboptimal molecular response to imatinib in e1a2 BCR-ABL chronic myeloid leukemia. OXFORD: Published Letters [DOI] [Details]
(1997)Inflammation, aspirin, and the risk of cardiovascular disease.
Cahill, MR;Perry, IJ (1997) Inflammation, aspirin, and the risk of cardiovascular disease. BOSTON: Published Letters [Details]

Teaching Activities

Teaching Interests

Contribution to teaching in Medicine and Pathology in Cork University Hospital. Teaching at undergraduate and postgraduate level. 
Examminer for Pathology and final Medicine

Examminer for the Royal College of Pathologists (UK) -examining 2-3 tomes per year in London and Leicester for FRCPath in Haematology. 

Occassional lecture for School of Pharmacy and Biosciences postgraduate programme, Public Health and MSc in Obstetrics. 


Contact details

Search profiles by name

Search profiles by topic

Pathology

Paiteolaíocht

UCC Department of Pathology, Cork University Hospital, Wilton, Cork, Ireland

Top