Lecturer In Pharmaceutics
School of Pharmacy
Cavanagh Pharmacy Building
University College Cork
Cork
Ireland

T: +353-21-490-1667
F: +353-21-490-1656
E: a.crean@ucc.ie

Total Career Publications: 29

Publications 2008-2014: 25

Patents: 3

Total Citations: 205

h-index: 7

Total Career Research Income: €3,041,379

Research Income (2008-2014): €2,830,524

PhDs Graduated (Career): 7

PhDs Graduated (2008-2014): 7

Dr. Abina Crean graduated with a degree in Pharmacy from Robert Gordon's University, Aberdeen, Scotland in 1992.  In 1997, she completed a PhD in Pharmaceutics in the School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin. Dr. Crean was employed as a formulation scientist with Elan Pharmaceutical Technologies between 1997 and 2001 and as a Process Development Pharmacist at Servier (Ireland) Industries between 2002 and 2003.

Since joining the newly established School of Pharmacy in UCC. She has been actively involved in the development of the new research facilities and curriculum. As PI, she established a pharmaceutical technology research group in UCC and supervised a range research projects in the areas of pharmaceutical manufacturing and formulation science. A key element of her research is active collaborative projects with a number of pharmaceutical companies both SME and large multi-nationals. She is a funded researcher in both the SFI funded SSPC - Synthesis and Solid State Pharmaceutical Research Centre and CÚRAM - The Centre for Research in Medical Devices, as well as PI in the EI/IDA funded Pharmaceutical Manufacturing Technology Centre.

Research Interests

My research interests are focused on the development of high quality, effective medicines through thorough investigation and understanding of the properties and associated behaviour of constituent materials (both API and excipients). 

Examples of current research projects include

  • Development of quality by design strategies to study the critical material attributes of pharmaceutical excipients
  • Enabling continuous pharmaceutical solid oral dosage from manufacture through identification, control and monitoring of critical material attributes 
  • Formulation and characterisation of microneedle drug and vaccine delivery systems
  • Development of silica-based drug formulations to enhance the oral bioavailability of therapeutic compounds challenged by poor-water solubility
  • Biophysical characterisation, processing and formulation of peptide, protein and vaccine materials
  • Manipulation of commercial dosage forms for administration to elderly patients

 
 

Peer Reviewed Journals

YearPublication
(2014)'Enhancement of the in vitro penetration of quercetin through pig skin by combined microneedles and lipid microparticles'
Paleco R., Vučen S.R., Crean A.M., Moore A.C., Scalia S (2014) 'Enhancement of the in vitro penetration of quercetin through pig skin by combined microneedles and lipid microparticles'. International Journal of Pharmaceutics, [DOI] [Details]
(2014)'The Use of PAT and Off-line Methods for Monitoring of Roller Compacted Ribbon and Granule Properties with a View to Continuous Processing'
M. A. P. McAuliffe, G. E. O’Mahony, C. A. Blackshields, J. A. Collins, D. P. Egan, L. Kiernan, E. O’Neill, S. Lenihan, G. M. Walker, A. M. Crean (2014) 'The Use of PAT and Off-line Methods for Monitoring of Roller Compacted Ribbon and Granule Properties with a View to Continuous Processing'. Organic Process Research & Development, [DOI] [Details]
(2013)'Production of dissolvable microneedles using an atomised spray process: Effect of microneedle composition on skin penetration'
McGrath MG, Vucen S, Vrdoljak A, Kelly A, O'Mahony C, Crean AM, Moore AC. (2013) 'Production of dissolvable microneedles using an atomised spray process: Effect of microneedle composition on skin penetration'. European Journal of Pharmaceutical Science, Epub ahead of print [DOI] [Details]
(2013)'Comparison of fenofibrate-mesoporous silica drug-loading processes for enhanced drug delivery'
Ahern, RJ,Hanrahan, JP,Tobin, JM,Ryan, KB,Crean, AM (2013) 'Comparison of fenofibrate-mesoporous silica drug-loading processes for enhanced drug delivery'. European Journal of Pharmaceutical Sciences, 50 :400-409 [DOI] [Details]
(2013)'Improved percutaneous delivery of ketoprofen using combined application of nanocarriers and silicon microneedles'
Vucen, SR,Vuleta, G,Crean, AM,Moore, AC,Ignjatovic, N,Uskokovic, D (2013) 'Improved percutaneous delivery of ketoprofen using combined application of nanocarriers and silicon microneedles'. Journal of Pharmacy and Pharmacology, 65 :1451-1462 [DOI] [Details]
(2012)'An Analysis of the Influence of Multiple Processing Factors on the Characteristics of Bioactive-Loaded Beads Prepared by Extrusion-Spheronisation'
Kuang, SS,Oliveira, JC,Crean, AM (2012) 'An Analysis of the Influence of Multiple Processing Factors on the Characteristics of Bioactive-Loaded Beads Prepared by Extrusion-Spheronisation'. Food and Bioprocess Technology, 5 :55-64 [DOI] [Details]
(2012)'Coated microneedle arrays for transcutaneous delivery of live virus vaccines'
Vrdoljak, A,McGrath, MG,Carey, JB,Draper, SJ,Hill, AVS,O'Mahony, C,Crean, AM,Moore, AC (2012) 'Coated microneedle arrays for transcutaneous delivery of live virus vaccines'. Journal of controlled release : official journal of the Controlled Release Society, 159 (1):34-42 [DOI] [Details]
(2012)'The influence of supercritical carbon dioxide (SC-CO2) processing conditions on drug loading and physicochemical properties'
Ahern, RJ,Crean, AM,Ryan, KB (2012) 'The influence of supercritical carbon dioxide (SC-CO2) processing conditions on drug loading and physicochemical properties'. International Journal of Pharmaceutics, 439 :92-99 [DOI] [Details]
(2011)'Evaluation of the influence of granulation processing parameters on the granule properties and dissolution characteristics of a modified release drug'
Ring, DT,Oliveira, JCO,Crean, A; (2011) 'Evaluation of the influence of granulation processing parameters on the granule properties and dissolution characteristics of a modified release drug'. Advanced Powder Technology, 22 :245-252 [DOI] [Details]
(2011)'Determination of parameters for successful spray coating of silicon microneedle arrays'
McGrath MG, Vrdoljak A, O'Mahony C, Oliveira JC, Moore AC, Crean AM; (2011) 'Determination of parameters for successful spray coating of silicon microneedle arrays'. International Journal of Pharmaceutics, 415 :140-149 [DOI] [CORA Link] [Details]
(2011)'A comparative study of spray-dried and freeze-dried hydrocortisone/polyvinyl pyrrolidone solid dispersions'
Rakesh Dontireddy, Abina M Crean; (2011) 'A comparative study of spray-dried and freeze-dried hydrocortisone/polyvinyl pyrrolidone solid dispersions'. Drug Development and Industrial Pharmacy, 37 (10):1141-1149 [DOI] [Details]
(2011)'Microneedle Array Design Determines the Induction of Protective Memory CD8+ T Cell Responses Induced by a Recombinant Live Malaria Vaccine in Mice'
John B. Carey, Frances E. Pearson, Anto Vrdoljak, Marie G. McGrath, Abina M. Crean, Patrick T. Walsh, Timothy Doody, Conor O'Mahony, Adrian V. S. Hill, Anne C. Moore; (2011) 'Microneedle Array Design Determines the Induction of Protective Memory CD8+ T Cell Responses Induced by a Recombinant Live Malaria Vaccine in Mice'. PloS ONE, 6 (7) [DOI] [Details]
(2011)'A Modified Surface on Titanium Deposited by a Blasting Process'
C. O'Sullivan, P. O'Hare, G. Byrne, L. O'Neill, K. B. Ryan and A. M. Crean (2011) 'A Modified Surface on Titanium Deposited by a Blasting Process'. Coatings, 1 (1):53-71 [Details]
(2010)'Deposition of substituted apatites with anticolonizing properties onto titanium surfaces using a novel blasting process'
O'Sullivan, C. and O'Hare, P. and O'Leary, N. D. and Crean, A. M. and Ryan, K. and Dobson, A. D. W. and O'Neill, L.; (2010) 'Deposition of substituted apatites with anticolonizing properties onto titanium surfaces using a novel blasting process'. Journal of Biomedical Materials Research, 95B (1):141-149 [DOI] [Details]
(2010)'Development of stabilized vaccines with needle-free devices for targeted skin immunization'
Moore, A. C., Crean, A. M., O¿Mahony; (2010) 'Development of stabilized vaccines with needle-free devices for targeted skin immunization'. European Pharmaceutical Review, 15 (6):56-60 [CORA Link] [Details]
(2010)'A Methodology for Knowledge Management in Biopharmaceutical Production'
Coakley, Jennifer; Hogan, Nicola; McGuire, Linda; Griffin, Brendan; Casey, Colman; Campbell, Cliff; Crean, Abina; (2010) 'A Methodology for Knowledge Management in Biopharmaceutical Production'. Pharmaceutical Engineering, 30 (3):30-40 [Details]
(2010)'Microencapsulation as a tool for incorporating bioactive ingredients into food'
Kuang, SS; Oliveira, JC; Crean, AM; (2010) 'Microencapsulation as a tool for incorporating bioactive ingredients into food'. Critical Reviews in Food Science and Nutrition, 50 (10):951-961 [Details]
(2002)'Comparative physicochemical properties of hydrocortisone-PVP composites prepared using supercritical carbon dioxide by the GAS anti-solvent recrystallization process, by coprecipitation and by spray drying'
Corrigan, O. I, Crean. A. M; (2002) 'Comparative physicochemical properties of hydrocortisone-PVP composites prepared using supercritical carbon dioxide by the GAS anti-solvent recrystallization process, by coprecipitation and by spray drying'. International Journal of Pharmaceutics, 245 (1-2):75-82 [Details]

Books

YearPublication
(2009)The Physicochemical Basis of Pharmaceuticals.
Humphrey Moynihan and Abina Crean; (2009) The Physicochemical Basis of Pharmaceuticals. Oxford: Oxford University Press. [Details]

Other Journals

YearPublication
(2010)'Development of Stabilised Vaccines with Needle-Free Devices for Targeted Skin Immunization'
A. Crean, C. O’Mahony and A. C. Moore (2010) 'Development of Stabilised Vaccines with Needle-Free Devices for Targeted Skin Immunization' European Pharmaceutical Review, 15 (6) :56-60. [Details]

Conference Publications

YearPublication
(2013)EuPAT 6: Sixth pan-European QbD & PAT Science Conference
Graham E. O’Mahony, Michael A. P. McAuliffe, Caroline Blackshields, Sandra Lenihan, David Egan, John A. Collins, Luke Kiernan, Gavin M. Walker, Eamonn O’Neill and Abina M. Crean (2013) Near infrared spectroscopy for real-time monitoring of roller-compacted ribbon density EuPAT 6: Sixth pan-European QbD & PAT Science Conference Porto, , 23-SEP-13 - 24-SEP-13 [Details]
(2013)EuPAT 6: Sixth pan-European QbD & PAT Science Conference
O’Mahony G, McAuliffe M, Blackshields C, Collins JA, Egan D, Kiernan L, Crean AM, Lenihan S, Walker GM and O’Neill E (2013) A study of the effects of roller compaction parameters on ribbon and granule properties by off-line and in-line methods with a view to continuous processing EuPAT 6: Sixth pan-European QbD & PAT Science Conference Porto, , 23-SEP-13 - 24-SEP-13 [Details]
(2013)Skin Vaccination Summit
Moore, A.,Allen, E.,O'Mahony, C.,Crean, A. (2013) ImmuPatch microneedle systems for addressing unmet needs in immunization programmes Skin Vaccination Summit Seattle, USA, , 05-DEC-13 [Details]
(2013)UCC School of Pharmacy Research Day
Nicholas D. Mullins, Anita R. Maguire, Humphrey A. Moynihan, Florence O. McCarthy, Simon E. Lawrence, Abina Crean, and Jonathan Thompson (2013) Degradation of Gentamicin Sulfate on Coated Titanium Surfaces UCC School of Pharmacy Research Day University College Cork, , 23-SEP-13 [Details]
(2013)35th All-Ireland Schools of Pharmacy Conference
Allen, E.,Crean, A.,O’Mahony, C.,Moore, A. C. (2013) Influenza Vaccination using Dissolvable ImmuPatchInfluenza Vaccination using Dissolvable ImmuPatch 35th All-Ireland Schools of Pharmacy Conference Belfast, UK, [Details]
(2012)UKICRS annual meeting, Aston University
Ahern, R. J., Ryan, K. B., Crean. A. M. (2012) Investigation and comparison of various drug-loading processes onto Mesoporous Silica UKICRS annual meeting, Aston University [Details]
(2012)2nd International Conference on Microneedles: Microneedles 2012
A. M. Crean, M. G. McGrath, C. O’Mahony, A. Vrdoljak and A. C. Moore (2012) Dissolvable ImmuPatch Microneedles for Drug Delivery 2nd International Conference on Microneedles: Microneedles 2012 Cork, , 13-MAY-12 - 15-MAY-12 [Details]
(2012)Microneedles 2012
Moore, A.,Vrdoljak, A.,McGrath, M.,Draper, S.,Hill, A.,Crean, A.,O'Mahony, C. (2012) ImmuPatch vaccination Microneedles 2012 Cork, Ireland, [Details]
(2011)5th International Granulation Workshop
D.T, Ring, J.C. Oliveira and A. Crean; (2011) Developing better process understanding; the role of the granulation process, materials properties and storage environment on drug release from a matrix tablet 5th International Granulation Workshop [Details]
(2011)38th Annual Meeting Controlled Release Society
M.G. McGrath, C.O¿Mahony, A. Vrdoljak, A.C. Moore, A.M. Crean; (2011) Design of Dissolvable Microneedles for Drug Delivery 38th Annual Meeting Controlled Release Society National Harbor, Maryland, U.S.A, [Details]
(2011)38th Annual Meeting Controlled Release Society
John B. Carey, Frances E. Pearson, Anto Vrdoljak, Abina M. Crean, Conor O¿Mahony, Adrian V.S. Hill, Anne C. Moore; (2011) Immunization using ImmuPatch Silicon Microneedle Arrays results in Enhanced T 38th Annual Meeting Controlled Release Society National Harbor, Maryland, U.S.A, [Details]
(2011)Transactions of 38th Annual Meeting and Exposition of the Controlled Release Society
R. J. Ahern, K. B. Ryan, A. M. Crean. (2011) Enhanced dissolution and stability properties of supercritical fluid processed fenofibrate-silica systems Transactions of 38th Annual Meeting and Exposition of the Controlled Release Society Maryland, U.S.A, July 2011, , 30-JUL-11 - 03-AUG-11 [Details]
(2011)38th Annual Meeting and Exposition of the Controlled Release Society
Vrdoljak, A.,McGrath, M. G.,Crean, A.,O'Mahony, C.,Moore, A. C. (2011) Development of ImmuPatch arrays coated with live vaccine 38th Annual Meeting and Exposition of the Controlled Release Society Maryland, USA, [Details]
(2011)British Association for Crystal Growth Annual Conference 2011
D. E. Horgan, D. M. Kelly, K. S. Eccles, S. E. Lawrence, H. A. Moynihan, R. Aherne, D. Ring, A. Crean (2011) Phenacetin as a Model Compound for Particle Engineering British Association for Crystal Growth Annual Conference 2011 University College London, , 10-JUL-11 - 12-JUL-11 [Details]
(2011)XXth Conference of the Groupment des Pharmacochimistes de l'Arc Atlantiques
Danielle E. Horgan, Dawn, M. Kelly, Kevin S. Eccles, Robert Aherne, Denis Ring, Abina Crean, Simon E. Lawrence, Humphrey A. Moynihan (2011) Phenacetin as a Model Compound for Particle Engineering XXth Conference of the Groupment des Pharmacochimistes de l'Arc Atlantiques UCC, , 01-SEP-11 - 02-SEP-11 [Details]
(2010)All Ireland Schools of Pharmacy Research Seminar
McCarthy, C., Ahern, R., Crean, A.M., Ryan, K; (2010) Investigation of Process and Formulation Parameters Impacting on Mesoporous Silica as a Carrier for Poorly soluble Drugs All Ireland Schools of Pharmacy Research Seminar Queen's University Belfast, , 29-MAR-10 - 30-MAR-10 [Details]
(2010)AAPS National Biotechnology Conference
Farag, F.F., O'Driscoll, C.M., Crean, A.M.; (2010) Formulation and storage conditions affecting the conformation and degradation of salmon calcitonin delivery systems AAPS National Biotechnology Conference San Francisco, [Details]
(2010)90th Annual Meeting of the British Association of Dermatologists
McAleer, M.,Moore, A.,Crean, A.,O'Mahony, C.,Bourke, J. F. (2010) A proof of concept study to investigate the efficacy of microneedle arrays in the administration of local anaesthetic in human skin 90th Annual Meeting of the British Association of Dermatologists Manchester, UKManchester, UK, , pp.101-117101 [Details]
(2010)12th International Conference on Perspectives in Percutaneous Penetration
M. G. McGrath, C. O¿Mahony, J. B. Carey, A. Vrdoljak, A. C. Moore and A. M. Crean; (2010) Spray Coating of Silicon Microneedle Patches for Intradermal Drug Delivery 12th International Conference on Perspectives in Percutaneous Penetration [Details]
(2010)First International Conference on Microneedles
Moore A.C., Carey J.B., Pearson F., Vrdoljak A., McGrath M., Draper S.J., Gilbert S.C., Hill A.V.S., Crean A. and O¿Mahony C., ; (2010) Enhanced Immune Responses induced by ImmuPatch Transcutaneous Vaccination First International Conference on Microneedles Atlanta, Georgia, , 24-MAY-10 - 26-MAY-10 [Details]
(2010)Perspectives in Percutaneous Penetreation
Moore A.C., Carey J.B., McGrath M. Pearson F.E., Vrdoljak A. Hill A.V.S., Crean A. and O¿Mahony C. ; (2010) Percutaneous immununization using ImmuPatch: Comparison of vaccine localisation and induction of antibody and T cell responses in a pre-clinical model Perspectives in Percutaneous Penetreation La Grande Motte, France, , 06-APR-10 - 10-APR-10 [Details]
(2010)First International Conference on Microneedles
McGrath M., Vrdoljak A., O¿Mahony C., Carey J.B., Moore A.C. and Crean A.; (2010) Percutaneous Vaccine Delivery Using Microneedles First International Conference on Microneedles Atlanta, Georgia, , 24-MAY-10 - 26-APR-10 [Details]
(2010)Modern Mucosal Vaccines and Adjuvants
Moore A.C., Carey J.B, Pearson F.E., Vrdoljak A., McGrath M., Draper S.J., Gilbert S.C., Hill A.V.S., Crean A. and O¿Mahony C. ; (2010) Enhanced T cell and Antibody Responses induced by ImmuPatch Transdermal Vaccination Modern Mucosal Vaccines and Adjuvants Dublin, Ireland, , 28-APR-10 - 30-APR-10 [Details]
(2010)4th Vaccine and ISV Annual Global Congress
A.C. Moore, J. Carey, F. Pearson, A. Vrdoljak, M. McGrath, S. Draper, S. Gilbert, A. Hill, A. Crean and C. O¿Mahony; (2010) Percutaneous Immunization using ImmuPatch: Needle-free vaccination that results in stronger T cell and antibody responses compared to traditional immunization routes 4th Vaccine and ISV Annual Global Congress Vienna, Austria, , 03-OCT-10 - 05-OCT-10 [Details]
(2009)36rd Annual meeting of the Controlled Release Society
Blackshields, C., McHugh, C., Duffy, P., Madigan, K., Cullen, A., Leonard, T., Crean, A.; (2009) Impact of Film Properties and Drug Physicochemical Properties on Diffusion through a Poly (Vinyl Alcohol) Film for the development of GIRESTM 36rd Annual meeting of the Controlled Release Society [Details]
(2009)AAPS Annual Meeting
Caroline Blackshields, Catherine McHugh, Thomas Leonard, Alan Cullen, Kieran Madigan, Patricia Duffy, Abina Crean; (2009) Control of Rate of Gas Generation for a Gastrointestinal Retention System (GIRES) AAPS Annual Meeting Los Angeles, [Details]
(2009)Transactions of 36th Annual meeting of the Controlled Release Society
O'Callaghan, J, Ryan, K., Hanrahan, J. P., Crean, A. M.; (2009) Mesoporous Silica for Optimised Drug delivery Transactions of 36th Annual meeting of the Controlled Release Society [Details]
(2008)35th Annual meeting of the Controlled Release Society
Blackshields. C.A, Conway. E. C, Crean. A. M; (2008) Alginate based beads for controlled release of Lebobupivacaine Base 35th Annual meeting of the Controlled Release Society [Details]
(2008)35th Annual meeting of the Controlled Release Society
Reddy. R.D, Crean. A.M; (2008) Hydrocortisone - PVP solid dispersions prepared from aqueous-solutions 35th Annual meeting of the Controlled Release Society [Details]
(2006)British Pharmaceutical Conference
Ring, D, Oliveira, F.A.R ., Twomey, M., Crean, A.; (2006) Process Optimisation for a Modified Release (MR) Tablet Using Production Data British Pharmaceutical Conference [Details]
(2007)Workshop on Bioencapsulation XV
Kuang, S. S., Oliveira, J. C. and Crean, A.M.; (2007) Development and characterization of microcapsules containing acetylsalicylic acid for long term suspension in acidic aqueous environment Workshop on Bioencapsulation XV [Details]
(2006)33rd Annual meeting of the Controlled Relsease Society
Blackshields, C.A, Oliveira, J., Moynihan, H. A, Crean. A. M; (2006) The influence of Processing Parameters on Alginate-Chitosan Bead Formation 33rd Annual meeting of the Controlled Relsease Society [Details]
(2006)British Pharmaceutical Conference
Blackshields, C. A, Oliveira, J., Moynihan, H.A., Crean, A.M.; (2006) Alginate-Chitosan Beads: Determining the Influence of Processing Parameters on Bead Formation British Pharmaceutical Conference [Details]
(2005)British Pharmaceutical Conference
Cararro, C., Crean, A.M.; (2005) A viscometric study of the critical concentration of PVP solutions British Pharmaceutical Conference [Details]
(2005)Schools of Pharmacy Research Seminar
Caroline A. Blackshields, Ken J. Devine, Humphrey. A. Moynihan, Abina M. Crean; (2005) The effect of pH on Levobupivacaine free base solubility and retention on reverse phase HPLC . In: * eds. Schools of Pharmacy Research Seminar Trinity College Dublin, , 21-MAR-05 - 22-MAR-05 , pp.*-* [Details]

Patents

 Patent NumberTitleInventorGranted
US20130110078Vaccination Method Using Microneedle Arrays Anne C. Moore, Frances Pearson, Adrian V.S. Hill, Abina M. Crean, Conor O'Mahony, Marie G. McGrath, John B. Carey02-MAY-13
WO2012066506Method Abina M. Crean, Marie G. McGrath, Conor O'Mahony, Anto Vrdoljak, Anne C. Moore, John B. Carey,23-AUG-12
EP2640356Method of Fabricating a Microneedle Anto Vrdoljak, Abina. M. Crean, Marie. G. Mcgrath, Conor O'mahony, Anne Clare Moore, John Carey18-NOV-11

Conference Contributions

YearPublication
(2014)Pharmacists in Industry Education and Regulatory AGM,
A. M. Crean (2014) Microneedles; Delivery and Diagnostics. [Invited Oral Presentation], Pharmacists in Industry Education and Regulatory AGM, Dublin , 13-DEC-14. [Details]
(2014)Design of amorphous drug systems optimised for enhanced dissolution,
Crean A.M. (2014) Amorphous by Design. [Invited Oral Presentation], Design of amorphous drug systems optimised for enhanced dissolution, University of Bradford, UK , 23-APR-14. [Details]
(2014)The Modes of Action of Vaccine Adjuvants,
O. Flynn, E. Allen, K. Dillane, A. Crean , E. Norton and A. Moore (2014) Immunogenicity of dmLT Adjuvanted Vaccines in ImmuPatch Dissolvable Microneedle. [Oral Presentation], The Modes of Action of Vaccine Adjuvants, Seattle, WA, USA , 08-OCT-14 - 13-OCT-14. [Details]
(2013)Almac Symposium, Cork 2013,
Crean A.M. (2013) Stabilisation of the amorphous drug state for enhanced oral delivery. [Invited Oral Presentation], Almac Symposium, Cork 2013, University College Cork , 09-SEP-13. [Details]
(2012)Sharebiotech: Fostering Open Innovation in Biotechnology,
Crean, A.M., Moore A.C., O'Mahony C. (2012) ImmuPatch: a skin-deep approach to vaccination and drug delivery. [Invited Oral Presentation], Sharebiotech: Fostering Open Innovation in Biotechnology, Pamplona , 10-MAY-12 - 11-MAY-12. [Details]
(2008)Amorphous Materials, Challenge or Opportunity,
Crean, A.M; (2008) Preparation of Amorphous Material using Solid Dispersions. [Invited Oral Presentation], Amorphous Materials, Challenge or Opportunity, Bath, UK , 18-MAR-08 - 18-MAR-08. [Details]
(2006)2006 All-Ireland Schools of Pharmacy 28th Research Seminar,
Caroline A. Blackshields, Jorge Oliveira, Humphrey A. Moynihan and Abina M. Crean; (2006) Alginate-Chitosan Beads: Determining the Influence of Processing Parameters on Bead Formation. [Poster Presentation], 2006 All-Ireland Schools of Pharmacy 28th Research Seminar, Queen's University Belfast School of Pharmacy , 10-APR-06 - 11-APR-06. [Details]
(2008)British Pharmaceutical Conference,
Crean, A.M; (2008) Solid Dispersion Technology. [Oral Presentation], British Pharmaceutical Conference, Manchester, UK , 08-OCT-08 - 08-OCT-08. [Details]

Education

 YearInstitutionQualificationSubject
1992Robert Gordon's University BSc PharmPharmacy
1997Trinity College Dublin PHDPharmaceutics

Teaching Interests

Undergraduate teaching: Pharmacy degree course module coordinator for module Introduction to Pharmaceutics: Formulation Science and major contributor to modules Pharmaceutical Technology, Novel Drug Delivery Systems and Pharmaceutical Biotechnology 

Postgraduate teaching: MSc (Pharmaceutical Technology and Quality Systems) module coordinator for modules in; Pharmaceutical Manufacturing - API to Finished Product and  Pharmaceutical Plant and Process: From Design through Validation. Masters in Applied Sciences (Biotechnology) a contributor to module Biopharmaceuticals; Formulation Design, Secondary Processing and Regulatory Compliance. 

Recent Postgraduates

 Graduation YearStudent NameInstitutionDegree TypeThesis Title
2012Denis Ring University College CorkPHDAnalysis and modelling of the influence of high shear wet granulation process parameters on critical quality attributes of an active pharmaceutical ingredient using robust design of experiments
2012Caroline O’Sullivan University College CorkPHDNovel coatings for hard tissue implants
2013Sean Cullen University College CorkM.Sc.The impact of excipient state on the structure and stability of lyophilized biopharmaceuticals
2011Marie McGrath University College CorkPHDDesign and characterisation of Microneedles for Percutaneous Vaccine Delivery
2012Fatma Farag PHDAn investigation of the chemical and physical stability of salmon calcitonin formulations
2013Robert Ahern University College CorkPHDApplication of mesoporous silica for the oral delivery of poorly water-soluble drugs
2010Rakesh Dontireddy University College CorkPHDInvestigation of dissolution properties of amorphous drug and drug-carrier systems
2008Caroline Blackshields University College CorkPHDDevelopment of hydrogel based drug delivery systems of local anaesthetics
2014Aisling Sheehan University College CorkM.Sc.An investigation into influenza vaccine stability in a dissolvable microneedle formulation

Current Postgraduate Students

 StudentDegree Type
Allen Evin Anthony Doctoral Degree
Mc Gillicuddy Aoife Catherine Doctoral Degree
Mc Carthy Carol Doctoral Degree
Crowley Mary Ellen Doctoral Degree

Modules Taught

 Term (ID))TitleLinkSubject
2015Biopharmaceuticals: Formulation Design, Secondary Processing and Regulatory compliance PF6301Biopharmaceuticals: Formulation Design, Secondary Processing and Regulatory compliance
2015Pharmaceutical Plant and Process: From Design through Validation PF6207Pharmaceutical Plant and Process: From Design through Validation
2015Pharmaceutical Manufacturing - API to Finished Product PF6202Pharmaceutical Manufacturing - API to Finished Product
2015Intro to Pharmaceutics: Formulation ScienceI PF1012Intro to Pharmaceutics: Formulation ScienceI
2015Pharmaceutical Technology PF2008Pharmaceutical Technology