Aideen Sullivan graduated from University College Dublin in 1992 with a BSc (First Class Honours) in Pharmacology. She obtained a PhD in Neuropharmacology from the University of Cambridge, UK, in 1995. She worked in Imperial College London School of Medicine as a post-doctoral researcher from 1995-1998, on a project funded by the Parkinson's Disease Society. In 1998, she was appointed as Lecturer in the Department of Anatomy at UCC; she was promoted to Senior Lecturer in 2006 and to Professor (Scale 2) in 2014 and appointed Head of the Department of Anatomy and Neuroscience in March 2021.
Upon her appointment to UCC, Aideen was actively involved in establishing the BSc in Neuroscience, the first Neuroscience degree in Ireland, and she taught on this degree since 1998, and was Academic Director until 2017. Recently, she led the development of a new cross-College BSc degree programme in Medical and Health Sciences (CK707), which had its first student intake in 2018.
Biography
Professor Aideen Sullivan is Head of the Department of Anatomy and Neuroscience. She leads an active research group, focused on novel approaches to the treatment of Parkinson's disease. Her particular interest is the development of neuroprotective therapies, which have the potential to slow or reverse the progression of this debilitating disease.Aideen Sullivan graduated from University College Dublin in 1992 with a BSc (First Class Honours) in Pharmacology. She obtained a PhD in Neuropharmacology from the University of Cambridge, UK, in 1995. She worked in Imperial College London School of Medicine as a post-doctoral researcher from 1995-1998, on a project funded by the Parkinson's Disease Society. In 1998, she was appointed as Lecturer in the Department of Anatomy at UCC; she was promoted to Senior Lecturer in 2006 and to Professor (Scale 2) in 2014 and appointed Head of the Department of Anatomy and Neuroscience in March 2021.
Upon her appointment to UCC, Aideen was actively involved in establishing the BSc in Neuroscience, the first Neuroscience degree in Ireland, and she taught on this degree since 1998, and was Academic Director until 2017. Recently, she led the development of a new cross-College BSc degree programme in Medical and Health Sciences (CK707), which had its first student intake in 2018.
In 2006, Aideen was awarded a Postgraduate Certificate in Teaching and Learning in Higher Education from UCC. She practices research-led teaching and encourages capable students to pursue research careers. She provides mentoring to undergraduate and postgraduate students and to colleagues. In 2010, she attained a FETAC certificate (awarded Distinction) in Peer-Mentoring. She has been an active participant in UCC's "Through the Glass Ceiling" Programme for Female Academics and Researchers (2011-13). In 2015, she was awarded a scholarship to participate in the Leadership Foundation's Aurora programme for women in Higher Education. She is Chair of the 'Flexible Working' Working Group for UCC's Athena SWAN Institutional application in 2020, and a member of UCC's main Athena SWAN steering group and of the College of Medicine and Health's Athena SWAN steering group.
Aideen is active in promoting Neuroscience and stem cell research in Ireland. She visits Parkinson’s support groups throughout Ireland, speaking to patients and their carers, clinicians and nurses, about recent advances in the research field. She has organised several conferences in the areas of Parkinson’s disease, stem cells and Neuroscience research, including the highly successful BRAINTALK Parkinson’s Community Meeting and Exhibition in 2015 (https://www.ucc.ie/en/braintalk/) and Brain Connections in 2018 (https://www.ucc.ie/en/cns/news/cork-neuroscience-centre--brain-connections-open-day.html). She undertakes visits to primary and secondary schools, to promote understanding and awareness of science and medicine. She has delivered talks and organised the Neuroscience information stand at each of UCC's Open Days for Schools since 1998.
Professor Sullivan is Editor-in-Chief of Neuronal Signaling, an Open Access peer-reviewed journal published by the Biochemical Socierty through Portland Press (http://www.neuronalsignaling.org). She is a member of Neuroscience Ireland, FENS (Federation of European Neurosciences), NECTAR (Network of European CNS Transplantation and Restoration), the Anatomical Society of Great Britain and Ireland, and the Irish Network of Neural Stem Cell Investigators.
Research Interests
Research Interests
Parkinson’s disease (PD) is the second most common neurodegenerative disorder, affecting ~2% of people aged over 65. Since PD is an age-related disorder, its incidence is steadily escalating, due to increases in life-expectancy. Current treatments are successful in alleviating symptoms in the short-term but their long-term use is associated with significant side-effects, and they have no effect to slow down the disease progression. The immediate future holds a significant challenge for researchers to develop novel treatments for PD, which will be efficacious and safe for long-term use by patients. Such developments will be driven by advances in the understanding of neuropathology of PD as well as the development, maintenance and health of dopamine neurons, the cells that degenerate in PD. My research programme aims to address these challenges through a coherently-linked program focused on key thematic areas, using in vitro and in vivo models:
- Optimisation of neuroprotective therapies by the use of viral vectors to achieve long-term and targeted delivery of dopaminergic neurotrophic factors to the nigrostriatal system.
- Elucidation of the molecular mechanisms mediating the protective effects of neurotrophic factors, to facilitate the development of drugs for PD which target these signalling pathways.
- Discovery of biomarkers for PD, to enable earlier diagnosis and personalised medicine.
- Investigation of the mechanisms of neuronal cell degeneration in PD, using new animal models which closely mimic the neuropathology which occurs in this disease.
- Characterisation of the mechanisms of dopaminergic neuronal development and survival, to enhance the development of stem cell-based treatments for PD.
- Investigation of the role of epigenetic mechanisms in the neurodegenerative pathomechanics of PD.
Research Grants
| Project | Funding Body | Start Date | End Date | Award | |
|---|---|---|---|---|---|
| [IC/2003/42] {Sullivan Dr. A} N | Enterprise Irl | 01-APR-03 | 01-APR-04 | €6,700.00 | |
| Determining the neuroprotective and neurorestorative efficacy of AAV-hGDF5 in the AAV-a-synuclein rat model of Parkinson's. | Foundation Funded Research | 01-JUL-22 | 30-SEP-25 | €226,032.00 | |
| Research Donation | Irish Charities | 01-OCT-20 | 30-JUN-24 | €15,000.00 | |
| 'Identification of Smad-interacting protein 1 as a novel regulator of ventral midbrain dopaminergic neuron development.’ | Health Research Board | 01-OCT-14 | 30-SEP-15 | €45,000.00 | |
| [HEA 3 NNN-TCD] {Scallan,Dr.Martina} N | Higher Education authority | 01-JUN-02 | 30-SEP-08 | €92,109.00 | |
| [WELLCOME TRUST] {Sullivan Dr. A} V | Foreign Research Institute | 17-JUN-02 | 12-AUG-02 | €1,811.00 | |
| [HEA 3 NNN-TCD] {Sullivan,Dr.Aideen} N | Higher Education authority | 01-JUN-02 | 30-SEP-08 | €364,574.00 | |
| [RP/150/2002] {Dr A Sullivan } N | Health Research Board | 01-OCT-02 | 30-SEP-05 | €131,900.00 | |
| ‘Roles of Sip-1 in the development of midbrain dopaminergic neurons’ | Irish Research Council | 01-OCT-14 | 30-SEP-15 | €45,828.00 | |
| ‘Characterisation of cognitive deficits in the alpha-synuclein rat model of Parkinson’s disease.’ | Molecular Medicine Ireland | 01-OCT-13 | 30-SEP-16 | €32,100.00 | |
| The role of Smad transcription in dopanimergic neuron survival. | Foreign Research Institute | 01-JUN-12 | 27-JUL-12 | €1,768.00 | |
| Support for ‘Parkinson’s Disease: from Molecules to Movement’ conference | Neuroscience Ireland | 01-JAN-12 | 31-DEC-12 | €1,000.00 | |
| ‘Potential biomarkers for Parkinson’s disease: comparison of levels of neurotrophic factors in cerebrospinal fluid and serum of Parkinson’s disease patients with those in healthy controls.’ | UCC TRAP (Translational Research Access Programme) | 01-JAN-12 | 31-DEC-12 | €9,750.00 | |
| ‘The role of Smad transcription factors in dopaminergic neuron survival.’ | Wellcome Trust | 01-JUN-12 | 27-JUL-12 | €1,768.00 | |
| ‘NF-kappaB transcription factors as a molecular target for Parkinson’s disease therapy’ | Irish Research Council | 01-JUL-11 | 30-JUN-13 | €75,962.00 | |
| The role of Smad transcription factors in dopaminergic neuron survival. | Irish Research Council for Science, Engineering & Technology (IRCSET) | 01-OCT-10 | 30-SEP-13 | €72,000.00 | |
| ‘The role of Smad transcription factors in dopaminergic neuron survival’ | Irish Research Council | 01-OCT-10 | 30-SEP-13 | €72,000.00 | |
| ‘Defining the potential of GDF-5 as a novel therapeutic for Parkinson’s disease’ | Health Research Board | 01-OCT-09 | 30-SEP-12 | €147,051.00 | |
| ‘ Investigation of the effects of VP025 in progressive rat models of Parkinson’s disease: proteasome inhibition and 6-OHDA striatal lesion’ | Vasogen Inc., Canada | 01-JAN-06 | 31-DEC-07 | €118,250.00 | |
| HRB "Embryonic stem cells for Parkinson's disease" | Health Research Board | 01-JAN-06 | 30-SEP-10 | €195,373.00 | |
| ‘Effect of pro-inflammatory cytokines on the fate of embryonic hippocampal neural precursor cells’ | Vasogen Inc., Canada | 01-JAN-06 | 31-DEC-08 | €48,000.00 | |
| ‘Embryonic stem cells for Parkinson’s disease | Health Research Board | 01-JAN-06 | 30-SEP-10 | €195,373.00 | |
| ‘Investigation of stem cell properties’ | Health Research Board | 01-JAN-06 | 31-DEC-06 | €32,700.00 | |
| ‘Analysis of the anti-inflammatory/neuroprotective effects of VP025 in progressive models of Parkinson’s disease’ | Vasogen Inc., Canada | 31-JAN-05 | 31-DEC-06 | €115,250.00 | |
| ‘The role of inflammation and p38 in 6-hydroxydopamine-induced dopaminergic neuronal death – implications for Parkinson’s disease’ | Irish Research Council | 01-JAN-04 | 31-MAR-08 | €75,962.00 | |
| The role of inflammation and p38 in 6-hydroxydopamin-induced dopaminergic neuronal .. | Irish Research Council for Science, Engineering & Technology (IRCSET) | 01-OCT-04 | 31-MAR-08 | €75,962.00 | |
| ‘Analysis of the anti-inflammatory/neuroprotective effects of novel phospholipids-based drug formulation in a rat model of Parkinson’s disease’ | Vasogen Inc., Canada | 01-JAN-04 | 31-DEC-05 | €115,250.00 | |
| ‘Confocal Imaging System’ | Health Research Board | 01-JAN-04 | 31-DEC-04 | €327,068.00 | |
| ‘Wnts and TGF-beta interactions in midbrain dopaminergic neuron development’ | Enterprise Ireland | 01-APR-03 | 01-APR-04 | €6,700.00 | |
| ‘Viral vectors for delivery of neurotrophins in models of Parkinson's disease’ | Higher Education Authority (HEA) | 01-JUN-02 | 30-SEP-08 | €92,109.00 | |
| 'Development of new therapies for Parkinson's disease' | Higher Education Authority | 01-JUN-02 | 30-SEP-08 | €364,574.00 | |
| ‘Generation of an enriched population of dopaminergic neurons for transplantation in Parkinson's disease' | Irish Research Council | 01-JAN-02 | 31-DEC-06 | €66,675.00 | |
| ‘Astroglial diversity and selective dopaminergic neuronal degeneration: implications for Parkinson's disease’ | Health Research Board | 01-JAN-02 | 30-DEC-05 | €103,200.00 | |
| ‘Establishment of neurotrophin-expressing dopaminergic cells for transplantation in Parkinson's disease’ | Health Research Board | 01-OCT-02 | 30-SEP-05 | €131,900.00 | |
| ‘Investigation of the role of GDF-5 in the developing and adult brain.’ | Irish Research Council | 01-JAN-02 | 31-DEC-04 | €51,000.00 | |
| ‘Stem cells for Parkinson's disease’ | Enterprise Ireland | 01-JAN-02 | 31-DEC-02 | €6,700.00 | |
| ‘Investigation of the immune response to a neurotrophin-expressing cell line in a rat model of Parkinson's disease’ | Health Research Board | 01-JUN-02 | 01-OCT-02 | €1,280.00 | |
| ‘Examination of a GDF5-expressing cell line in a rat model of Parkinson's disease’ | Wellcome Trust | 17-JUN-02 | 12-AUG-02 | €1,811.00 | |
| ‘Use of a cell line expressing the neurotrophin GDF-5 to enhance the efficacy of transplanted dopaminergic neurons in a rat model of Parkinson's disease’ | Health Research Board | 01-JAN-00 | 31-DEC-01 | €38,105.00 | |
| ‘The use of the neurotrophin GDF-5 to enhance transplantation in Parkinson's disease’ | Health Research Board | 01-JAN-00 | 01-JAN-01 | €640.00 | |
| ‘The role of GDF-5 and GDNF neurotrophins and glial-neuronal interactions in models of Parkinson's disease’ | Health Research Board | 01-JAN-99 | 30-DEC-02 | €45,820.00 |
Contract Researchers
| Researcher Name | Project | Role | Funding Body | |
|---|---|---|---|---|
| Dr Shane Hegarty | 'Identification of Smad-interacting protein 1 as a novel regulator of ventral midbrain dopaminergic neuron development.’ | Postdoctoral Researcher | National University of Ireland (NUI) | |
| Dr Louise Collins | ‘Molecular mechanisms of dopaminergic neuronal development’ | Postdoctoral Researcher | Health Research Board | |
| Dr Sinead Walsh | ‘NF-kappaB transcription factors as a molecular target for Parkinson’s disease therapy’ | Postdoctoral Researcher | Irish Research Council | |
| Dr Andre Toulouse | ‘Development of new therapies for Parkinson's disease’ | Postdoctoral Researcher | Higher Education Authority | |
| Dr David O’Sullivan | ‘Embryonic stem cells for Parkinson’s disease’ | Postdoctoral Researcher | Health Research Board | |
| Dr Tara Kelly | ‘Viral vectors for delivery of neurotrophins in models of Parkinson's disease’ | Postdoctoral Researcher | Higher Education Authority | |
| Dr Andrew Fisher | ‘Analysis of the anti-inflammatory / neuroprotective effects of novel phospholipids-based drug formulation in a rat model of Parkinson’s disease’ (co-supervised by Dr. Yvonne Nolan). | Postdoctoral Researcher | Vasogen Inc., Canada | |
| Patrick Fitzgerald | Analysis of the anti-inflammatory/neuroprotective effects of VP025 in progressive models of Parkinsons disease. (co-supervised by Dr. Yvonne Nolan). | Research Assistant | Vasogen Inc., Canada | |
| Eleanor Tuohy | Analysis of the anti-inflammatory/neuroprotective effects of novel phospholipids-based drug formulation in a rat model of Parkinsons disease (co-supervised by Dr. Yvonne Nolan). | Research Assistant | Vasogen Inc., Canada | |
| Suzanne Crotty | Analysis of the anti-inflammatory/neuroprotective effects of VP025 in progressive models of Parkinsons disease (co-supervised by Dr. Yvonne Nolan). | Research Assistant | Vasogen Inc., Canada | |
| Dawn Harris | Analysis of the anti-inflammatory/neuroprotective effects of novel phospholipids-based drug formulation in a rat model of Parkinsons disease (co-supervised by Dr. Yvonne Nolan). | Research Assistant | Vasogen Inc., Canada |
Publications
Peer Reviewed Journals
| Year | Publication | |
|---|---|---|
| (2022) | 'Peripheral administration of the Class-IIa HDAC inhibitor MC1568 partially protects against nigrostriatal neurodegeneration in the striatal 6-OHDA rat model of Parkinson's disease' Mazzocchi M;Goulding SR;Morales-Prieto N;Foley T;Collins LM;Sullivan AM;O'Keeffe GW; (2022) 'Peripheral administration of the Class-IIa HDAC inhibitor MC1568 partially protects against nigrostriatal neurodegeneration in the striatal 6-OHDA rat model of Parkinson's disease'. Brain Behav Immun, 102 [DOI] [Details] | |
| (2022) | 'Diet quality, sleep and quality of life in Parkinson's disease: a cross-sectional study' Dunk, D;Mulryan, P;Affonso, S;O'Keeffe, GW;O'Keeffe, M;Sullivan, AM (2022) 'Diet quality, sleep and quality of life in Parkinson's disease: a cross-sectional study'. Irish Journal of Medicine, [DOI] [Details] | |
| (2022) | 'Gene Co-expression Analysis of the Human Substantia Nigra Identifies ZNHIT1 as an SNCA Co-expressed Gene that Protects Against a-Synuclein-Induced Impairments in Neurite Growth and Mitochondrial Dysfunction in SH-SY5Y Cells' McCarthy E;Barron A;Morales-Prieto N;Mazzocchi M;McCarthy CM;Collins LM;Sullivan AM;O'Keeffe GW; (2022) 'Gene Co-expression Analysis of the Human Substantia Nigra Identifies ZNHIT1 as an SNCA Co-expressed Gene that Protects Against a-Synuclein-Induced Impairments in Neurite Growth and Mitochondrial Dysfunction in SH-SY5Y Cells'. Molecular Neurobiology, [DOI] [Details] | |
| (2022) | 'Growth differentiation factor 5: a neurotrophic factor with neuroprotective potential in Parkinson's disease' Goulding SR;Anantha J;Collins LM;Sullivan AM;O'Keeffe GW; (2022) 'Growth differentiation factor 5: a neurotrophic factor with neuroprotective potential in Parkinson's disease'. Neural Regeneration Research, 17 (1) [DOI] [Details] | |
| (2021) | 'NME1 Protects Against Neurotoxin-, a-Synuclein- and LRRK2-Induced Neurite Degeneration in Cell Models of Parkinson's Disease' Anantha J;Goulding SR;Tuboly E;O'Mahony AG;Moloney GM;Lomansey G;McCarthy CM;Collins LM;Sullivan AM;O'Keeffe GW; (2021) 'NME1 Protects Against Neurotoxin-, a-Synuclein- and LRRK2-Induced Neurite Degeneration in Cell Models of Parkinson's Disease'. Molecular Neurobiology, [DOI] [Details] | |
| (2021) | 'LMK235, a small molecule inhibitor of HDAC4/5, protects dopaminergic neurons against neurotoxin- and a-synuclein-induced degeneration in cellular models of Parkinson's disease' Mazzocchi M;Goulding SR;Wyatt SL;Collins LM;Sullivan AM;O'Keeffe GW; (2021) 'LMK235, a small molecule inhibitor of HDAC4/5, protects dopaminergic neurons against neurotoxin- and a-synuclein-induced degeneration in cellular models of Parkinson's disease'. Molecular and Cellular Neuroscience, 115 [DOI] [Details] | |
| (2021) | 'Quinacrine and Niclosamide Promote Neurite Growth in Midbrain Dopaminergic Neurons Through the Canonical BMP-Smad Pathway and Protect Against Neurotoxin and a-Synuclein-Induced Neurodegeneration' Goulding, Susan R.; Lévesque, Martin; Sullivan, Aideen M.; Collins, Louise M.; O’Keeffe, Gerard W. (2021) 'Quinacrine and Niclosamide Promote Neurite Growth in Midbrain Dopaminergic Neurons Through the Canonical BMP-Smad Pathway and Protect Against Neurotoxin and a-Synuclein-Induced Neurodegeneration'. Molecular Neurobiology, [DOI] [Full Text] [Details] | |
| (2021) | 'Alpha-synuclein alters the faecal viromes of rats in a gut-initiated model of Parkinson's disease' Stockdale SR;Draper LA;O'Donovan SM;Barton W;O'Sullivan O;Volpicelli-Daley LA;Sullivan AM;O'Neill C;Hill C; (2021) 'Alpha-synuclein alters the faecal viromes of rats in a gut-initiated model of Parkinson's disease'. Communications Biology, 4 (1) [DOI] [Details] | |
| (2020) | 'Growth differentiation factor 5 exerts neuroprotection in an a-synuclein rat model of Parkinson's disease' Goulding, Susan R.; Concannon, Ruth M.; Morales-Prieto, Noelia; Villalobos-Manriquez, Francisca; Clarke, Gerard; Collins, Louise M.; Lévesque, Martin; Wyatt, Sean L.; Sullivan, Aideen M.; O’Keeffe, Gerard W. (2020) 'Growth differentiation factor 5 exerts neuroprotection in an a-synuclein rat model of Parkinson's disease'. Brain, [DOI] [Full Text] [Details] | |
| (2020) | 'Association of distinct type 1 bone morphogenetic protein receptors with different molecular pathways and survival outcomes in neuroblastoma' Alshangiti AM;Wyatt SL;McCarthy E;Collins LM;Hegarty SV;Sullivan AM;O'Keeffe GW; (2020) 'Association of distinct type 1 bone morphogenetic protein receptors with different molecular pathways and survival outcomes in neuroblastoma'. Neuronal Signaling, 4 (1) [DOI] [Details] | |
| (2020) | 'Alterations in a-synuclein and PINK1 expression reduce neurite length and induce mitochondrial fission and Golgi fragmentation in midbrain neurons' Furlong R.;O'Keeffe G.;O'Neill C.;Sullivan A. (2020) 'Alterations in a-synuclein and PINK1 expression reduce neurite length and induce mitochondrial fission and Golgi fragmentation in midbrain neurons'. Neuroscience Letters, 720 [DOI] [Details] | |
| (2020) | 'Temporally Altered miRNA Expression in a Piglet Model of Hypoxic Ischemic Brain Injury' Casey S.;Goasdoue K.;Miller S.M.;Brennan G.P.;Cowin G.;O’Mahony A.G.;Burke C.;Hallberg B.;Boylan G.B.;Sullivan A.M.;Henshall D.C.;O’Keeffe G.W.;Mooney C.;Bjorkman T.;Murray D.M. (2020) 'Temporally Altered miRNA Expression in a Piglet Model of Hypoxic Ischemic Brain Injury'. Molecular Neurobiology, [DOI] [Details] | |
| (2020) | 'STRAP and NME1 Mediate the Neurite Growth-Promoting Effects of the Neurotrophic Factor GDF5' Anantha J.;Goulding S.R.;Wyatt S.L.;Concannon R.M.;Collins L.M.;Sullivan A.M.;O'Keeffe G.W. (2020) 'STRAP and NME1 Mediate the Neurite Growth-Promoting Effects of the Neurotrophic Factor GDF5'. Iscience, 23 (9) [DOI] [Details] | |
| (2019) | '4-Hydroxychalcone Induces Cell Death via Oxidative Stress in MYCN-Amplified Human Neuroblastoma Cells' Alshangiti AM;Tuboly E;Hegarty SV;McCarthy CM;Sullivan AM;O'Keeffe GW; (2019) '4-Hydroxychalcone Induces Cell Death via Oxidative Stress in MYCN-Amplified Human Neuroblastoma Cells'. Oxidative Medicine and Cellular Longevity, 2019 [DOI] [Details] | |
| (2019) | 'The Parkinson' disease gene PINK1 activates Akt via PINK1 kinase-dependent regulation of the phospholipid PI(3,4,5)P-3' Furlong, RM;Lindsay, A;Anderson, KE;Hawkins, PT;Sullivan, AM;O'Neill, C (2019) 'The Parkinson' disease gene PINK1 activates Akt via PINK1 kinase-dependent regulation of the phospholipid PI(3,4,5)P-3'. Journal of Cell Science, 132 [DOI] [Full Text] [Details] | |
| (2019) | 'Nigral overexpression of alpha-synuclein in a rat Parkinson's disease model indicates alterations in the enteric nervous system and the gut microbiome' O’Donovan, S.M., Crowley, E.K., Brown, J.R.-M., O’Sullivan, O., O’Leary, O.F., Timmons, S., Nolan, Y.M., Clarke, D.J., Hyland, N.P., Joyce, S.A., Sullivan, A.M., O’Neill, C (2019) 'Nigral overexpression of alpha-synuclein in a rat Parkinson's disease model indicates alterations in the enteric nervous system and the gut microbiome'. Neurogastroenterology and Motility, [DOI] [Details] | |
| (2019) | 'Gene Co-expression Analysis Identifies Histone Deacetylase 5 and 9 Expression in Midbrain Dopamine Neurons and as Regulators of Neurite Growth via Bone Morphogenetic Protein Signaling' Mazzocchi, M;Wyatt, SL;Mercatelli, D;Morari, M;Morales-Prieto, N;Collins, LM;Sullivan, AM;O'Keeffe, GW (2019) 'Gene Co-expression Analysis Identifies Histone Deacetylase 5 and 9 Expression in Midbrain Dopamine Neurons and as Regulators of Neurite Growth via Bone Morphogenetic Protein Signaling'. Frontiers In Cell And Developmental Biology, 7 [DOI] [Details] | |
| (2019) | 'The dietary flavonoid isoliquiritigenin is a potent cytotoxin for human neuroblastoma cells' Alshangiti AM;Togher KL;Hegarty SV;Sullivan AM;O'Keeffe GW; (2019) 'The dietary flavonoid isoliquiritigenin is a potent cytotoxin for human neuroblastoma cells'. Neuronal Signaling, 3 (1) [DOI] [Details] | |
| (2019) | 'Gene co-expression analysis of the human substantia nigra identifies BMP2 as a neurotrophic factor that can promote neurite growth in cells overexpressing wild-type or A53T a-synuclein' Goulding, Susan R.; Sullivan, Aideen M.; O'Keeffe, Gerard W.; Collins, Louise M. (2019) 'Gene co-expression analysis of the human substantia nigra identifies BMP2 as a neurotrophic factor that can promote neurite growth in cells overexpressing wild-type or A53T a-synuclein'. Parkinsonism & related disorders, [DOI] [Full Text] [Details] | |
| (2018) | 'Neuroprotective effects of voluntary running on cognitive dysfunction in an alpha-synuclein rat model of Parkinson's disease' Crowley, EK;Nolan, YM;Sullivan, AM (2018) 'Neuroprotective effects of voluntary running on cognitive dysfunction in an alpha-synuclein rat model of Parkinson's disease'. Neurobiology of Aging, 65 :60-68 [DOI] [Details] | |
| (2018) | 'Inhibition of miR-181a promotes midbrain neuronal growth through a Smad1/5-dependent mechanism: implications for Parkinson's disease' Hegarty SV;Sullivan AM;O'Keeffe GW; (2018) 'Inhibition of miR-181a promotes midbrain neuronal growth through a Smad1/5-dependent mechanism: implications for Parkinson's disease'. Neuronal Signaling, 2 (1) [DOI] [Details] | |
| (2018) | 'Evidence for dopaminergic axonal degeneration as an early pathological process in Parkinson's disease' O'Keeffe, Gerard W.; Sullivan, Aideen M. (2018) 'Evidence for dopaminergic axonal degeneration as an early pathological process in Parkinson's disease'. Parkinsonism & related disorders, [DOI] [Full Text] [Details] | |
| (2017) | 'Zeb2 is a negative regulator of midbrain dopaminergic axon growth and target innervation' Shane V. Hegarty, Sean L. Wyatt, Laura Howard, Elke Stappers, Danny Huylebroeck, Aideen M. Sullivan & Gerard W. O’Keeffe (2017) 'Zeb2 is a negative regulator of midbrain dopaminergic axon growth and target innervation'. Scientific Reports, 7 (1) [DOI] [Details] | |
| (2017) | 'Effects of intracerebral neurotrophic factor application on motor symptoms in Parkinson's disease: A systematic review and meta-analysis' Hegarty, S.V., Lee, D.J., O'Keeffe, G.W., Sullivan, A.M. (2017) 'Effects of intracerebral neurotrophic factor application on motor symptoms in Parkinson's disease: A systematic review and meta-analysis'. Parkinsonism & related disorders, 38 :19-25 [DOI] [Full Text] [Details] | |
| (2017) | 'Endocytosis contributes to BMP2-induced Smad signalling and neuronal growth' Hegarty, S.V., Sullivan, A.M., O’Keeffe, G.W. (2017) 'Endocytosis contributes to BMP2-induced Smad signalling and neuronal growth'. Neuroscience Letters, 643 :32-37 [DOI] [Full Text] [Details] | |
| (2017) | 'Romidepsin induces caspase-dependent cell death in human neuroblastoma cells' Hegarty, SV;Togher, KL;O'Leary, E;Solger, F;Sullivan, AM;O'Keeffe, GW (2017) 'Romidepsin induces caspase-dependent cell death in human neuroblastoma cells'. Neuroscience Letters, 653 :12-18 [DOI] [Details] | |
| (2017) | 'An Attitudinal Survey of Undergraduate Neuroscience Students Regarding Their Views on the Relevance of Lectures to their Education' O'Keeffe GW;Sullivan AM;McCarthy MM; (2017) 'An Attitudinal Survey of Undergraduate Neuroscience Students Regarding Their Views on the Relevance of Lectures to their Education'. Journal of Undergraduate Neuroscience Education, 16 (1) [Details] | |
| (2016) | 'Protocol for evaluation of neurotrophic strategies in Parkinson’s disease-related dopaminergic and sympathetic neurons in vitro' Hegarty, Shane V.; Sullivan, Aideen M.; O’Keeffe, Gerard W. (2016) 'Protocol for evaluation of neurotrophic strategies in Parkinson’s disease-related dopaminergic and sympathetic neurons in vitro'. Journal of Biological Methods, 3 (3) [DOI] [Full Text] [Details] | |
| (2016) | 'Distinct alterations in motor & reward seeking behavior are dependent on the gestational age of exposure to LPS-induced maternal immune activation' Straley ME;Van Oeffelen W;Theze S;Sullivan AM;O'Mahony SM;Cryan JF;O'Keeffe GW; (2016) 'Distinct alterations in motor & reward seeking behavior are dependent on the gestational age of exposure to LPS-induced maternal immune activation'. Brain Behav Immun, [DOI] [Details] | |
| (2016) | 'A Small Molecule Activator of p300/CBP Histone Acetyltransferase Promotes Survival and Neurite Growth in a Cellular Model of Parkinson's Disease' Hegarty S.V., O'Leary E., Solger F., Stanicka J., Sullivan A.M., O'Keeffe G.W. (2016) 'A Small Molecule Activator of p300/CBP Histone Acetyltransferase Promotes Survival and Neurite Growth in a Cellular Model of Parkinson's Disease'. Neurotoxicity Research, 30 (3):510-520 [DOI] [Full Text] [Details] | |
| (2015) | 'Class-IIa Histone Deacetylase Inhibition Promotes the Growth of Neural Processes and Protects Them Against Neurotoxic Insult' Collins L.M., Adriaanse L.J., Theratile S.D., Hegarty S.V., Sullivan A.M., O'Keeffe G.W. (2015) 'Class-IIa Histone Deacetylase Inhibition Promotes the Growth of Neural Processes and Protects Them Against Neurotoxic Insult'. Molecular Neurobiology, 51 (3):1432-1442 [DOI] [Details] | |
| (2015) | 'Nociceptin/Orphanin FQ Inhibits the Survival and Axon Growth of Midbrain Dopaminergic Neurons Through a p38-MAPK Dependent Mechanism' Collins LM;Dal Bo G;Calcagno M;Monzón-Sandoval J;Sullivan AM;Gutierrez H;Morari M;O'Keeffe GW; (2015) 'Nociceptin/Orphanin FQ Inhibits the Survival and Axon Growth of Midbrain Dopaminergic Neurons Through a p38-MAPK Dependent Mechanism'. Molecular Neurobiology, [DOI] [Details] | |
| (2014) | 'Canonical BMP-Smad Signalling Promotes Neurite Growth in Rat Midbrain Dopaminergic Neurons' Hegarty, SV;Collins, LM;Gavin, AM;Roche, SL;Wyatt, SL;Sullivan, AM;O'Keeffe, GW (2014) 'Canonical BMP-Smad Signalling Promotes Neurite Growth in Rat Midbrain Dopaminergic Neurons'. Neuromolecular medicine, 16 :473-489 [DOI] [Details] | |
| (2014) | 'Expression of endogenous Mkp1 in 6-OHDA rat models of Parkinson's disease' Collins LM, Gavin AM, Walsh S, Sullivan AM, Wyatt SL, O'Keeffe GW, Nolan YM, Toulouse A (2014) 'Expression of endogenous Mkp1 in 6-OHDA rat models of Parkinson's disease'. SpringerPlus, 3 [DOI] [Details] | |
| (2014) | '6-Hydroxydopamine induces distinct alterations in GDF5 and GDNF mRNA expression in the rat nigrostriatal system in vivo' Gavin AM, Walsh S, Wyatt SL, O'Keeffe GW*, Sullivan AM* (2014) '6-Hydroxydopamine induces distinct alterations in GDF5 and GDNF mRNA expression in the rat nigrostriatal system in vivo'. Neuroscience Letters, (561):176-181 [Details] | |
| (2014) | 'Knockdown of interleukin-1 receptor 1 is not neuroprotective in the 6-hydroxydopamine striatal lesion rat model of Parkinson's disease' Walsh, S., Gavin, A., Wyatt, S., O'Connor, C., Keeshan, K., Nolan, Y.M., O'Keeffe, G.W., Sullivan, A.M. (2014) 'Knockdown of interleukin-1 receptor 1 is not neuroprotective in the 6-hydroxydopamine striatal lesion rat model of Parkinson's disease'. The International journal of neuroscience, 125 (1):70-77 [DOI] [Details] | |
| (2014) | 'Ventral midbrain neural stem cells have delayed neurogenic potential in vitro' Hegarty S.V., Spitere K., O'Keeffe G.W., Sullivan A.M. (2014) 'Ventral midbrain neural stem cells have delayed neurogenic potential in vitro'. Neuroscience Letters, 559 :193-198 [DOI] [Details] | |
| (2013) | 'BMP2 and GDF5 induce neuronal differentiation through a Smad dependant pathway in a model of human midbrain dopaminergic neurons' Hegarty S.V., Sullivan A.M., O'Keeffe G.W. (2013) 'BMP2 and GDF5 induce neuronal differentiation through a Smad dependant pathway in a model of human midbrain dopaminergic neurons'. Molecular and Cellular Neuroscience, 56 :263-271 [DOI] [Details] | |
| (2013) | 'Mitogen-activated protein kinase phosphatase (MKP)-1 as a neuroprotective agent: promotion of the morphological development of midbrain dopaminergic neurons' Collins, L.M., O'Keeffe, G.W., Long-Smith, C.M., Wyatt, S.L., Sullivan, A.M., Toulouse, A., Nolan, Y.M. (2013) 'Mitogen-activated protein kinase phosphatase (MKP)-1 as a neuroprotective agent: promotion of the morphological development of midbrain dopaminergic neurons'. NeuroMolecular Medicine, 15 (2):435-446 [DOI] [Details] | |
| (2012) | 'Neurotrophic effects of growth/differentiation factor 5 in a neuronal cell line' Toulouse, A., Collins, G., Sullivan, A.M. (2012) 'Neurotrophic effects of growth/differentiation factor 5 in a neuronal cell line'. Neurotoxicity Research, 21 (3):256-265 [DOI] [Details] | |
| (2012) | 'A role for interleukin-1 beta in determining the lineage fate of embryonic rat hippocampal neural precursor cells' Green, HF;Treacy, E;Keohane, AK;Sullivan, AM;O'Keeffe, GW;Nolan, YM (2012) 'A role for interleukin-1 beta in determining the lineage fate of embryonic rat hippocampal neural precursor cells'. Molecular and Cellular Neuroscience, 49 :311-321 [DOI] [Details] | |
| (2012) | 'Transplantation of novel human GDF5-expressing CHO cells is neuroprotective in models of Parkinson's disease' Costello, D. J.,O'Keeffe, G. W.,Hurley, F. M.,Sullivan, A. M. (2012) 'Transplantation of novel human GDF5-expressing CHO cells is neuroprotective in models of Parkinson's disease'. Journal of Cellular and Molecular Medicine, 16 (10):2451-2460 [DOI] [Details] | |
| (2010) | 'Interleukin-1 beta contributes to dopaminergic neuronal death induced by lipopolysaccharide-stimulated rat glia in vitro' Long-Smith, C.M., Collins, L., Toulouse, A., Sullivan, A.M., Nolan Y.M. (2010) 'Interleukin-1 beta contributes to dopaminergic neuronal death induced by lipopolysaccharide-stimulated rat glia in vitro'. Journal of Neuroimmunology, 226 (1-2):20-26 [DOI] [Details] | |
| (2010) | 'Effects of GDF5 overexpression on embryonic rat dopaminergic neurones in vitro and in vivo' O’Sullivan, D.B., Harrison, P.T., Sullivan, A.M. (2010) 'Effects of GDF5 overexpression on embryonic rat dopaminergic neurones in vitro and in vivo'. Journal of Neural Transmission, 117 (5):559-572 [DOI] [Details] | |
| (2010) | 'Tumour necrosis factor-alpha impairs neuronal differentiation but not proliferation of hippocampal neural precursor cells: Role of Hes1' Keohane, A., Ryan, S., Maloney, E., Sullivan, A.M., Nolan Y.M. (2010) 'Tumour necrosis factor-alpha impairs neuronal differentiation but not proliferation of hippocampal neural precursor cells: Role of Hes1'. Molecular and cellular neurosciences, 43 (1):127-135 [DOI] [Details] | |
| (2008) | 'TAT-PAX6 protein transduction in neural progenitor cells: a novel approach for generation of dopaminergic neurones in vitro' Spitere, K., Toulouse, A., O’Sullivan, D.B., Sullivan, A.M. (2008) 'TAT-PAX6 protein transduction in neural progenitor cells: a novel approach for generation of dopaminergic neurones in vitro'. Brain Research, 1208 :25-34 [DOI] [Details] | |
| (2008) | 'Treatment with phosphotidylglycerol-based nanoparticles prevents motor deficits induced by proteasome inhibition: implications for Parkinson's disease' Fitzgerald, P., Mandel, A., Bolton, A.E., Sullivan, A.M., Nolan, Y.M. (2008) 'Treatment with phosphotidylglycerol-based nanoparticles prevents motor deficits induced by proteasome inhibition: implications for Parkinson's disease'. Behavioural Brain Research, 195 (2):271-274 [DOI] [Details] | |
| (2008) | 'Neuroprotective effects of novel phosphatidylglycerol-based phospholipids in the 6-hydroxydopamine model of Parkinson's disease' Crotty, S., Fitzgerald, P., Tuohy, E., Harris, D.M., Fisher, A., Mandel, A., Bolton, A. E., Sullivan, A.M., Nolan, Y.M. (2008) 'Neuroprotective effects of novel phosphatidylglycerol-based phospholipids in the 6-hydroxydopamine model of Parkinson's disease'. The European Journal of Neuroscience, 27 (2):294-300 [DOI] [Details] | |
| (2007) | 'Differential effects of GDF5 on the medial and lateral rat ventral mesencephalon' Clayton, K.B. and Sullivan, A.M. (2007) 'Differential effects of GDF5 on the medial and lateral rat ventral mesencephalon'. Neuroscience Letters, 427 (3):132-137 [DOI] [Details] | |
| (2007) | 'Expression of the cell surface markers mAb 2F7 and PSA-NCAM in the embryonic rat brain' Shanley, D.K. and Sullivan, A.M. (2007) 'Expression of the cell surface markers mAb 2F7 and PSA-NCAM in the embryonic rat brain'. Neuroscience Letters, 424 (3):165-169 [DOI] [Details] | |
| (2006) | 'Alterations in cellular phenotypes differentiating from embryonic rat brain neurosphere cultures by immunoselection of neuronal progenitors' Shanley, D.K. and Sullivan, A.M. (2006) 'Alterations in cellular phenotypes differentiating from embryonic rat brain neurosphere cultures by immunoselection of neuronal progenitors'. Brain Research, 1067 (1):85-94 [DOI] [Details] | |
| (2005) | 'The role of growth/differentiation factor 5 (GDF5) in the induction and survival of midbrain dopaminergic neurones: relevance to Parkinson's disease treatment' Sullivan, A.M., O'Keeffe, G.W. (2005) 'The role of growth/differentiation factor 5 (GDF5) in the induction and survival of midbrain dopaminergic neurones: relevance to Parkinson's disease treatment'. Journal of Anatomy, 207 (3):219-226 [DOI] [Details] | |
| (2005) | 'Donor age affects differentiation of rat ventral mesencephalic stem cells' O' Keeffe, G.W., Sullivan, A.M. (2005) 'Donor age affects differentiation of rat ventral mesencephalic stem cells'. Neuroscience Letters, 375 (2):101-106 [DOI] [Details] | |
| (2005) | 'Differential effects of growth/differentiation factor 5 and glial cell line-derived neurotrophic factor on dopaminergic neurons and astroglia in cultures of embryonic rat midbrain' Wood, T.K., McDermott, K.W., Sullivan, A.M. (2005) 'Differential effects of growth/differentiation factor 5 and glial cell line-derived neurotrophic factor on dopaminergic neurons and astroglia in cultures of embryonic rat midbrain'. Journal of Neuroscience Research, 80 (6):759-766 [DOI] [Details] | |
| (2004) | 'Expression of growth differentiation factor-5 in the developing and adult rat brain' O'Keeffe, G.W., Hanke, M., Pohl, J., Sullivan, A.M. (2004) 'Expression of growth differentiation factor-5 in the developing and adult rat brain'. Brain research. Developmental brain research, 151 (1-2):199-202 [DOI] [Details] | |
| (2004) | 'Neuroprotective effects of delayed administration of growth/ differentiation factor-5 in the partial lesion model of Parkinson's disease' Hurley, F. M.,Costello, D. J.,Sullivan, A. M. (2004) 'Neuroprotective effects of delayed administration of growth/ differentiation factor-5 in the partial lesion model of Parkinson's disease'. Experimental Neurology, 185 (2):281-289 [DOI] [Details] | |
| (2004) | 'Effects of growth/differentiation factor 5 on the survival and morphology of embryonic rat midbrain dopaminergic neurones in vitro' O'Keeffe, G.W., Dockery, P., Sullivan, A.M. (2004) 'Effects of growth/differentiation factor 5 on the survival and morphology of embryonic rat midbrain dopaminergic neurones in vitro'. Journal of Neurocytology, 33 (5):479-488 [DOI] [Details] | |
| (2004) | 'Heparin-binding epidermal growth factor-like growth factor: a component in chromaffin granules which promotes the survival of nigrostriatal dopaminergic neurones in vitro and in vivo' Hanke, M., Farkas, L., Jakob, M., Ries, R., Pohl, J., Sullivan, A.M. (2004) 'Heparin-binding epidermal growth factor-like growth factor: a component in chromaffin granules which promotes the survival of nigrostriatal dopaminergic neurones in vitro and in vivo'. Neuroscience, 124 (4):757-766 [DOI] [Details] | |
| (2003) | 'Growth/differentiation factor-15 (GDF-15), a novel member of the TGF-beta superfamily, promotes survival of lesioned mesencephalic dopaminergic neurons in vitro and in vivo and is induced in neurons following cortical lesioning' Strelau, J., Sullivan, A., Bottner, M., Lingor, P., Falkenstein, P., Suter-Crazzolara, C., Galter, D., Jaszai, J., Krieglstein, K., Unsicker, K. (2003) 'Growth/differentiation factor-15 (GDF-15), a novel member of the TGF-beta superfamily, promotes survival of lesioned mesencephalic dopaminergic neurons in vitro and in vivo and is induced in neurons following cortical lesioning'. Journal of neural transmission. Supplementum, (65):197-203 [Details] | |
| (2003) | 'Viability of dopaminergic neurones is influenced by serum and astroglial cells in vitro' Wood, TK;Sullivan, AM;McDermott, KW (2003) 'Viability of dopaminergic neurones is influenced by serum and astroglial cells in vitro'. Journal of Neurocytology, 32 :97-103 [Details] | |
| (2002) | 'TGF-beta and the regulation of neuron survival and death' Krieglstein, K;Strelau, J;Schober, A;Sullivan, A;Unsicker, K (2002) 'TGF-beta and the regulation of neuron survival and death'. Journal of physiology, Paris, 96 :25-30 [Details] | |
| (2002) | 'Growth Differentiation Factor-5 (GDF-5) expression in the rat brain: developmental regulator, potential treatment?' O'keeffe G;Costello Dj;Hanke M;Sullivan A; (2002) 'Growth Differentiation Factor-5 (GDF-5) expression in the rat brain: developmental regulator, potential treatment?'. Journal of Anatomy, 201 (5) [Details] | |
| (2000) | 'GDF-15/MIC-1 a novel member of the TGF-beta superfamily' Strelau, J., Bottner, M., Lingor, P., Suter-Crazzolara, C., Galter, D., Jaszai, J., Sullivan, A., Schober, A., Krieglstein, K., Unsicker, K. (2000) 'GDF-15/MIC-1 a novel member of the TGF-beta superfamily'. Journal of neural transmission. Supplementum, (60):273-276 [Details] | |
| (2000) | 'Growth/differentiation factor-15/macrophage inhibitory cytokine-1 is a novel trophic factor for midbrain dopaminergic neurons in vivo' Strelau, J., Sullivan, A., Bottner, M., Lingor, P., Falkenstein, P., Suter-Crazzolara, C., Galter, D., Jaszai, J., Krieglstein, K., Unsicker, K. (2000) 'Growth/differentiation factor-15/macrophage inhibitory cytokine-1 is a novel trophic factor for midbrain dopaminergic neurons in vivo'. The Journal of Neuroscience, 20 (23):8597-8603 [Details] | |
| (1999) | 'Neuroprotective effects of growth/differentiation factor 5 depend on the site of administration' Sullivan, AM;Opacka-Juffry, J;Pohl, J;Blunt, SB (1999) 'Neuroprotective effects of growth/differentiation factor 5 depend on the site of administration'. Brain Research, 818 :176-179 [Details] | |
| (1998) | 'Growth/differentiation factor 5 and glial cell line-derived neurotrophic factor enhance survival and function of dopaminergic grafts in a rat model of Parkinson's disease' Sullivan, A.M. Pohl, J., Blunt, S.B. (1998) 'Growth/differentiation factor 5 and glial cell line-derived neurotrophic factor enhance survival and function of dopaminergic grafts in a rat model of Parkinson's disease'. The European Journal of Neuroscience, 10 (12):3681-3688 [Details] | |
| (1998) | 'Long-term protection of the rat nigrostriatal dopaminergic system by glial cell line-derived neurotrophic factor against 6-hydroxydopamine in vivo' Sullivan, A.M. Opacka-Juffry, J., Blunt, S.B. (1998) 'Long-term protection of the rat nigrostriatal dopaminergic system by glial cell line-derived neurotrophic factor against 6-hydroxydopamine in vivo'. The European Journal of Neuroscience, 10 (1):57-63 [Details] | |
| (1997) | 'Growth/differentiation factor 5 protects nigrostriatal dopaminergic neurones in a rat model of Parkinson's disease' Sullivan, A.M. Opacka Juffry, J., Hotten, G., Pohl, J., Blunt, S.B. (1997) 'Growth/differentiation factor 5 protects nigrostriatal dopaminergic neurones in a rat model of Parkinson's disease'. Neuroscience Letters, 233 (2-3):73-76 [Details] | |
| (1996) | 'Endothelins induce Fos expression in neurons and glia in organotypic cultures of rat cerebellum' Sullivan, A.M. and Morton, A.J. (1996) 'Endothelins induce Fos expression in neurons and glia in organotypic cultures of rat cerebellum'. Journal of Neurochemistry, 67 :1409-1418 [DOI] [Details] | |
| (1996) | 'Cortical induction of c-fos by intrastriatal endothelin-1 is mediated via NMDA receptors' Sullivan, A.M. Reynolds, D.S., Thomas, K.L., Morton, A.J. (1996) 'Cortical induction of c-fos by intrastriatal endothelin-1 is mediated via NMDA receptors'. Neuroreport, 8 (1):211-216 [Details] | |
| (1996) | 'Lack of permanent nigrostriatal dopamine deficit following 6-hydroxydopamine injection into the rat striatum. Short communication' Opacka-Juffry, J., Ashworth, S., Sullivan, A.M. Banati, R.B., Blunt, S.B. (1996) 'Lack of permanent nigrostriatal dopamine deficit following 6-hydroxydopamine injection into the rat striatum. Short communication'. Journal of Neural Transmission, 103 (12):1429-1434 [DOI] [Details] |
Reviews
| Year | Publication | |
|---|---|---|
| (2022) | Growth differentiation factor 5: a neurotrophic factor with neuroprotective potential in Parkinson's disease. Goulding, SR;Anantha, J;Collins, LM;Sullivan, AM;O'Keeffe, GW (2022) Growth differentiation factor 5: a neurotrophic factor with neuroprotective potential in Parkinson's disease. MUMBAI: Reviews [DOI] [Details] | |
| (2020) | The potential of bone morphogenetic protein 2 as a neurotrophic factor for Parkinson's disease. Goulding SR;Sullivan AM;O'Keeffe GW;Collins LM; (2020) The potential of bone morphogenetic protein 2 as a neurotrophic factor for Parkinson's disease. Reviews [DOI] [Details] | |
| (2019) | Exercise as a therapeutic intervention for motor and non-motor symptoms in Parkinson's disease: Evidence from rodent models. Crowley EK;Nolan YM;Sullivan AM; (2019) Exercise as a therapeutic intervention for motor and non-motor symptoms in Parkinson's disease: Evidence from rodent models. Reviews [DOI] [Details] | |
| (2017) | Targeting bone morphogenetic protein signalling in midbrain dopaminergic neurons as a therapeutic approach in Parkinson's disease. O’Keeffe, G.W., Hegarty, S.V., Sullivan, A.M. (2017) Targeting bone morphogenetic protein signalling in midbrain dopaminergic neurons as a therapeutic approach in Parkinson's disease. Reviews [DOI] [Full Text] [Details] | |
| (2017) | Targeting transcriptional regulators to regenerate midbrain dopaminergic axons in Parkinson's disease. Hegarty SV;Sullivan AM;O'Keeffe GW; (2017) Targeting transcriptional regulators to regenerate midbrain dopaminergic axons in Parkinson's disease. Reviews [DOI] [Details] | |
| (2016) | The epigenome as a therapeutic target for Parkinson’s disease. Hegarty, S.V., Sullivan, A.M., O'Keeffe, G.W. (2016) The epigenome as a therapeutic target for Parkinson’s disease. Reviews [DOI] [Full Text] [Details] | |
| (2016) | Microbiota-gut-brain signalling in Parkinson's disease: Implications for non-motor symptoms. Felice, V.D., Quigley, E.M., Sullivan, A.M., O'Keeffe, G.W., O'Mahony, S.M. (2016) Microbiota-gut-brain signalling in Parkinson's disease: Implications for non-motor symptoms. Reviews [Details] | |
| (2016) | Neurotrophic factor therapy for Parkinson's disease: past, present and future. Sullivan AM;O'Keeffe GW; (2016) Neurotrophic factor therapy for Parkinson's disease: past, present and future. Reviews [DOI] [Details] | |
| (2015) | Zeb2: A multifunctional regulator of nervous system development. Hegarty S.V., Sullivan A.M., O'Keeffe G.W.; (2015) Zeb2: A multifunctional regulator of nervous system development. Reviews [DOI] [Details] | |
| (2014) | Roles for the TGFβ Superfamily in the Development and Survival of Midbrain Dopaminergic Neurons. Shane V. Hegarty, Aideen M. Sullivan, Gerard W. O’Keeffe (2014) Roles for the TGFβ Superfamily in the Development and Survival of Midbrain Dopaminergic Neurons. Reviews [DOI] [Details] | |
| (2013) | BMP-Smad 1/5/8 signalling in the development of the nervous system. Hegarty S.V., O'Keeffe G.W., Sullivan A.M. (2013) BMP-Smad 1/5/8 signalling in the development of the nervous system. Reviews [DOI] [Details] | |
| (2013) | Parkinson's Disease in the Nuclear Age of Neuroinflammation. Nolan Y.M., Sullivan A.M., Toulouse A. (2013) Parkinson's Disease in the Nuclear Age of Neuroinflammation. Reviews [DOI] [Details] | |
| (2013) | Midbrain dopaminergic neurons: a review of the molecular circuitry that regulates their development. Hegarty, S.V., Sullivan, A.M., O'Keeffe, G.W. (2013) Midbrain dopaminergic neurons: a review of the molecular circuitry that regulates their development. Reviews [DOI] [Details] | |
| (2009) | The influence of microglia on the pathogenesis of Parkinson's disease. Long-Smith CM;Sullivan AM;Nolan YM; (2009) The influence of microglia on the pathogenesis of Parkinson's disease. Reviews [DOI] [Details] | |
| (2020) | The class II histone deacetylases as therapeutic targets for Parkinson's disease. Mazzocchi M;Collins LM;Sullivan AM;O'Keeffe GW; (2020) The class II histone deacetylases as therapeutic targets for Parkinson's disease. Reviews [DOI] [Details] | |
| (2019) | Trophic factors for Parkinson's disease: Where are we and where do we go from here?. Paul, G;Sullivan, AM (2019) Trophic factors for Parkinson's disease: Where are we and where do we go from here?. HOBOKEN: Reviews [DOI] [Details] | |
| (2018) | Exercise as therapy for Parkinson's?. Crowley EK;Nolan YM;Sullivan AM; (2018) Exercise as therapy for Parkinson's?. Reviews [DOI] [Details] | |
| (2015) | Viral vector delivery of neurotrophic factors for Parkinson's disease therapy. Kelly, MJ;O'Keeffe, GW;Sullivan, AM (2015) Viral vector delivery of neurotrophic factors for Parkinson's disease therapy. NEW YORK: Reviews [DOI] [Details] | |
| (2014) | Neurotrophic factors: from neurodevelopmental regulators to novel therapies for Parkinson's disease. Hegarty, SV;O'Keeffe, GW;Sullivan, AM (2014) Neurotrophic factors: from neurodevelopmental regulators to novel therapies for Parkinson's disease. SHENYANG: Reviews [DOI] [Details] | |
| (2008) | Progress in Parkinson's disease - Where do we stand?. Toulouse, A;Sullivan, AM (2008) Progress in Parkinson's disease - Where do we stand?. OXFORD: Reviews [DOI] [Details] |
Conference Publications
| Year | Publication | |
|---|---|---|
| (2017) | Neuroscience Ireland SM O’Donovan, EK Crowley, J Browne, O O’Sullivan, OF O’Leary, S Timmons, YM Nolan, PW O’Toole, DJ Clarke, NP Hyland, SA Joyce, AM Sullivan, C O’Neill (2017) Investigation of the brain ↔ gut axis in the raav2/6-alpha-synuclein pd model: alterations in enteric nervous system pathology and the gut microbiome Neuroscience Ireland NUI Galway, , 28-AUG-17 - 29-AUG-17 [Details] | |
| (2017) | Neurogastroenterology and Motiltiy S O'Donovan, EK Crowley, J Browne, O O'Sullivan, OF O'Leary, S Timmons, YM Nolan, PW O'Toole, DJ Clarke, NP Hyland, SA Joyce, AM Sullivan, C O'Neill (2017) Investigation of the brain gut axis in the rAAV-alpha-synuclein PD model: Reveals enteric nervous system pathology and alterations in the gut microbiome Neurogastroenterology and Motiltiy , pp.33-34 [DOI] [Details] | |
| (2017) | AD/PDTM 2017, the 13th International Conference on Alzheimer's and Parkinson's Diseases and Related Neurological Disorders O’Donovan SM, Crowley E, Browne J, O’Sullivan O, O’Leary OF, Timmons S, Nolan YM, O’Toole PW, Clarke DJ, Hyland NP, Joyce SA, Sullivan AM, O’Neill C (2017) The brain ↔gut axis in Parkinson’s disease: defining gut pathology and the impact of exercise in the rAAV-α-synuclein rat model of PD AD/PDTM 2017, the 13th International Conference on Alzheimer's and Parkinson's Diseases and Related Neurological Disorders , 29-MAR-17 - 02-APR-17 [Details] | |
| (2017) | NEUROGASTROENTEROLOGY AND MOTILITY S O'Donovan, EK Crowley, J Browne, O O'Sullivan, OF O'Leary, S Timmons, YM Nolan, PW O'Toole, DJ Clarke, NP Hyland, SA Joyce, AM Sullivan, C O'Neill (2017) Investigation of the brain gut axis in the rAAV-alpha-synuclein PD model: Reveals enteric nervous system pathology and alterations in the gut microbiome NEUROGASTROENTEROLOGY AND MOTILITY [Details] | |
| (2016) | Young Neuroscientists Symposium 2016 Grant Hanni M., Sullivan A.M., Toulouse A. (2016) SHSY-5Y cell model:differentiation and neuroprotection Young Neuroscientists Symposium 2016 Trinity College, Dublin. Ireland, , 01-SEP-16 [Details] | |
| (2016) | New Horizons in Translational Research 2016 Grant Hanni M., Sullivan A.M., Toulouse A. (2016) SHSY-5Y cell model:differentiation and neuroprotection New Horizons in Translational Research 2016 University College Cork, Cork, Ireland, , 08-DEC-16 [Details] | |
| (2016) | New Horizons in Medical Research, December 8th 2016, University College Cork SM O’Donovan, E Dolan, OF O’Leary, S Timmons, PW O’Toole, DJ Clarke, NP Hyland, SA Joyce, AM Sullivan, C O’Neill (2016) The brain ↔ gut axis in Parkinson’s disease (PD): Central nervous system administration of rAAV-α-synuclein altered gut pathophysiology and increased gut inflammation in the rAAV-α-synuclein rat model of PD New Horizons in Medical Research, December 8th 2016, University College Cork [Details] | |
| (2016) | APC Microbiome Institute Symposium SM O’Donovan, E Dolan, OF O’Leary, S Timmons, PW O’Toole, DJ Clarke, NP Hyland, SA Joyce, AM Sullivan, C O’Neill (2016) The brain ↔ gut axis in Parkinson’s disease: defining gut pathophysiology in the rAAV-α-synuclein rat model of PD APC Microbiome Institute Symposium [Details] | |
| (2016) | 2016 Biochemical Society Meeting: Inflammatory diseases - mechanisms and clinical perspectives, 3—4 November 2016, Maynooth University, Ireland SM O’Donovan, E Dolan, OF O’Leary, S Timmons, PW O’Toole, DJ Clarke, NP Hyland, SA Joyce, AM Sullivan, C O’Neill (2016) The brain ↔ gut axis in Parkinson’s disease (PD): Central nervous system administration of rAAV-α-synuclein altered gut pathophysiology and increased gut inflammation in the rAAV-α-synuclein rat model of PD 2016 Biochemical Society Meeting: Inflammatory diseases - mechanisms and clinical perspectives, 3—4 November 2016, Maynooth University, Ireland [Details] | |
| (2016) | 29th ECNP Congress of Applied & Translational Neuroscience Hegarty S.V., O'Leary E., Solger F., Wyatt S.L., Sullivan A.M., O'Keeffe G.W.. (2016) S.12.01. Novel neurotrophic strategy: interrogation of intracellular molecules regulating growth of midbrain dopaminergic neurons 29th ECNP Congress of Applied & Translational Neuroscience 26 (S2), , pp.S127-S127 [DOI] [Details] | |
| (2014) | RAMI Section of Biomedical Sciences Annual Meeting 2014 Hegarty S.V., Collins L.M., Gavin A.M., Roche S.L., Wyatt S.L., Sullivan A.M., O'Keeffe G.W. (2014) Canonical BMP-SMAD Signalling Promotes Neurite Growth in Embryonic Rat Midbrain Dopaminergic Neurons RAMI Section of Biomedical Sciences Annual Meeting 2014 [DOI] [Details] | |
| (2012) | Neuroscience Ireland Conference, Dublin Collins, L.M., O'Keeffe, G.W., Long-Smith, C.M., Sullivan, A.M., Toulouse, A., Nolan, Y.M. (2012) Mitogen-activated protein kinase phosphatase (MKP)-1 promotes the morphological development of midbrain dopaminergic neurons. Poster Prize . In: Irish J. Med. Sci eds. Neuroscience Ireland Conference, Dublin [Details] | |
| (2012) | Neuroscience Ireland Conference, Dublin Hegarty, S.V., Sullivan, A.M., O'Keeffe G.W. (2012) GDF5 and BMP2 have differential effects on rat ventral mesencephalic neural stem cells, depending on their developmental stage . In: Irish J. Med. Sci eds. Neuroscience Ireland Conference, Dublin [Details] | |
| (2012) | Neuroscience Ireland Conference, Dublin Walsh, S., Keeshan, K., Nolan, Y.M., O'Keeffe, G.W., Sullivan, A.M. (2012) The effect of IL-1R1 shRNA intra-nigral administration in a hemi-parkinsonian 6-hydroxydopamine rat model . In: Irish J. Med. Sci eds. Neuroscience Ireland Conference, Dublin [Details] | |
| (2011) | IBRO World Congress of Neuroscience, Florence, Italy Gavin, A., Wyatt, S., Sullivan, A.M., O'Keeffe, G.W. (2011) Analysis of the temporal expression and neurotrophic effects of GDNF in the developing rat nigrostriatal system IBRO World Congress of Neuroscience, Florence, Italy [Details] | |
| (2011) | Neuroscience Ireland Conference, Maynooth Hegarty, S.V., Sullivan, A.M., O'Keeffe G.W. (2011) The Development of Rat Ventral Mesencephalic Neural Stem Cells in vitro . In: Irish J. Med. Sci eds. Neuroscience Ireland Conference, Maynooth [Details] | |
| (2010) | Neuroscience Ireland Conference, Dublin Crampton, S.J., Sullivan, A.M., O'Keeffe, G.W. (2010) Stereological analysis of the brachypod mouse brain . In: Irish J. Med. Sci eds. Neuroscience Ireland Conference, Dublin [Details] | |
| (2010) | Neuroscience Ireland Conference, Dublin Gavin, A., Wyatt, S., Sullivan, A.M., O'Keeffe, G.W. (2010) Spatiotemporal analysis of GDF-5 expression in the developing rat nigrostriatal system . In: Irish J. Med. Sci eds. Neuroscience Ireland Conference, Dublin [Details] | |
| (2009) | International Conference on Alzheimer's and Parkinson's Diseases Toulouse A., Collins G.C., Sullivan, A.M. (2009) The neurotrophic effects of Growth/Differentiation Factor 5 in a neuronal cell line International Conference on Alzheimer's and Parkinson's Diseases Prague, Czech Republic, , 11-MAR-09 - 15-MAR-09 [Details] | |
| (2006) | Neuroscience Ireland Meeting, Cork Crotty, S., Fitzgerald, P., Harris, D.M., Fisher, A., Mandel, A., Bolton, A.E., Sullivan, A.M., Nolan, Y.M. (2006) Neuroprotective evidence of a novel phospholipid-based drug formulation in a rat model of Parkinson’s disease . In: Irish J Med Sci eds. Neuroscience Ireland Meeting, Cork Cork, [Details] | |
| (2005) | JOURNAL OF ANATOMY Sullivan, AM;O'Keeffe, GW (2005) The role of growth/differentiation factor 5 (GDF5) in the induction and survival of midbrain dopaminergic neurones: relevance to Parkinson's disease treatment JOURNAL OF ANATOMY , pp.219-226 [Details] | |
| (2005) | Society for Neuroscience meeting, Washington, USA Shanley, D.K., Sullivan, A.M. (2005) Identification, isolation and expansion of neuronal precursor cells: A step-by-step process involving microarray analysis, immunoselection and neurosphere culture . In: Soc. Neurosci. Abs. 708.2 eds. Society for Neuroscience meeting, Washington, USA [Details] | |
| (2005) | VII European Meeting on Glial Cell Function in Health and Disease. Amsterdam Barrett, R.J., McDermott, K.W., Sullivan, A.M. (2005) The effects of astroglial and neurotrophic interactions on the survival of dopaminergic neurons in vitro VII European Meeting on Glial Cell Function in Health and Disease. Amsterdam [Details] | |
| (2005) | Royal Academy of Medicine in Ireland Biomedical Section Meeting, Dublin Harris, D.M., Fisher, A., Harkin, A.J., Bolton, A.E., Sullivan, A.M., Nolan Y.M. (2005) Novel phospholipid-based drug formulation prevents degeneration of dopaminergic neurons from substantia nigra in a rat model of Parkinson’s disease . In: Irish J Med Sci 174 eds. Royal Academy of Medicine in Ireland Biomedical Section Meeting, Dublin [Details] | |
| (2005) | International Congress on Parkinson’s Disease and Related Disorders, Berlin, Germany Toulouse, A., Sullivan, A.M. (2005) Investigation of the neurotrophic effects of growth/differentiation factor 5 in an in vitro model of Parkinson’s disease. Prize for Best Poster . In: Parkinsonism and Related Disorders, Vol. 11 eds. International Congress on Parkinson’s Disease and Related Disorders, Berlin, Germany [Details] | |
| (2005) | Society for Neuroscience meeting, Washington, USA Spitere, K., Toulouse, A., Sullivan, A.M. (2005) T.A.T-Pax6 protein transduction in neural progenitor cells: A novel strategy for dopaminergic neuron generation . In: Soc. Neurosci. Abs. 142.2 eds. Society for Neuroscience meeting, Washington, USA [Details] | |
| (2005) | 16th International Congress on Parkinson’s Disease and Related Disorders, Berlin, Germany Kelly, T.A., Harrison, P.T., Scallan, M.F., Sullivan, A.M. (2005) Lentiviral-mediated delivery of growth/differentiation factor-5 attenuates parkinsonian symptoms in the rat . In: Parkinsonism & Related Disorders Volume 11, Supplement 2 eds. 16th International Congress on Parkinson’s Disease and Related Disorders, Berlin, Germany Berlin, [Details] | |
| (2004) | 4th Forum of European Neuroscience Lisbon Portugal Shanley, D.K., Sullivan, A.M. (2004) Cellular differentiation in neurosphere cultures of embryonic day 14 rat cortical and striatal tissue . In: FENS Abstr. Vol.2, A107.15 eds. 4th Forum of European Neuroscience Lisbon Portugal [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland Barrett, R.J., McDermott, K.W., Sullivan, A.M. (2004) The effects of GDNF, GDF-5 and astroglia on the survival of rat mesencephalic dopaminergic neurons in vitro . In: J. Anat. 205 (6) eds. Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland O’Sullivan, D.B., Harrison, P.T., Sullivan, A.M. (2004) Rat ventral mesencephalic cultures transfected with a plasmid expressing growth/differentiation factor 5 exhibit improved dopaminergic neuronal survival . In: J. Anat. 205 (6) eds. Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland Toulouse, A., Sullivan, A.M. (2004) Investigation of the effects of the neurotrophin GDF-5 on the growth and differentiation of SH-SY5Y cells . In: J. Anat. 205 (6) eds. Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland [Details] | |
| (2004) | 15th Biennial Meeting of the International Society for Developmental Neuroscience, Edinburgh, Scotland, United Kingdom Spitere, K., Sullivan, A.M. (2004) A comparison of genetic cascades involved in induction of dopaminergic neuronal fate in the developing rodent ventral mesencephalon, embryonic stem cells and neural stem cells . In: Int. J. Dev. Neurosci., Vol. 22 eds. 15th Biennial Meeting of the International Society for Developmental Neuroscience, Edinburgh, Scotland, United Kingdom , pp.601-728 [Details] | |
| (2004) | 4th Forum of European Neuroscience Lisbon Portugal Clayton, K.B., McDonnell, E., Sullivan, A.M. (2004) Growth/differentiation factor 5 (GDF5) expression in the developing rat brain . In: FENS Abstr. Vol.2, A0732.6 eds. 4th Forum of European Neuroscience Lisbon Portugal [Details] | |
| (2004) | 4th Forum of European Neuroscience Lisbon Portugal. July 2004 Barrett, R.J., McDermott, K.W., Sullivan, A.M. (2004) The roles of GDNF, GDF-5 and astroglia on the survival of mesencephalic dopaminergic neurons in vitro . In: FENS Abstr. Vol.2, A019.4 eds. 4th Forum of European Neuroscience Lisbon Portugal. July 2004 [Details] | |
| (2004) | 4th Forum of European Neuroscience Lisbon Portugal O’Sullivan, D.B., Sullivan, A.M., Harrison, P.T. (2004) Establishment of neurotrophin-expressing dopaminergic cells for transplantation in Parkinson’s disease . In: FENS Abstr. Vol.2, A053.17 eds. 4th Forum of European Neuroscience Lisbon Portugal [Details] | |
| (2004) | 4th Forum of European Neuroscience Lisbon Portugal Toulouse, A., Sullivan, A.M. (2004) Investigation of the role of GDF-5 in the growth and differentiation of human neuroblastoma cells . In: FENS Abstr. Vol.2, A196.18 eds. 4th Forum of European Neuroscience Lisbon Portugal [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland Harty, M., Sullivan, A.M., McDermott, K.W. (2004) Astroglial diversity in rat dopaminergic nuclei: implications for selective neuronal degeneration and Parkinson’s disease . In: J. Anat. 205 (6) 529 eds. Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland Kelly, T.A., Harrison, P.T., Scallan, M.F., Sullivan, A.M. (2004) Viral vectors to deliver neurotrophin genes to a rat model of Parkinson’s disease . In: J. Anat. 205 (6) eds. Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland Shanley, D.K., Sullivan, A.M. (2004) In vitro expansion and differentiation of neurospheres derived from embryonic day 14 rat cortical and striatal tissue . In: J. Anat. 205 (6) eds. Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland Sullivan, A.M. (2004) Effects of growth/differentiation factor 5 (GDF5) on the induction and survival of midbrain dopaminergic neurons . In: J. Anat. 205 (6) 524 eds. Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland Clayton, K.B., McDonnell, E., Sullivan, A.M. (2004) Investigation of the spatio-temporal pattern of expression of the neurotrophin growth/differentiation factor 5 in the developing and adult rat brain . In: J. Anat. 205 (6) eds. Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland Spitere, K., Sullivan, A.M. (2004) Characterisation of the cellular populations and dopaminergic gene cascade in rat ventral mesencephalic neural stem cell cultures . In: J. Anat. 205 (6) eds. Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland [Details] | |
| (2004) | Society for Neuroscience Meeting, San Diego, USA Toulouse, A., O’Keeffe, G.W., Sullivan, A.M. (2004) Dopaminergic induction from expanded rat ventral mesencephalic progenitor cells by GDF5 and BMP2 requires signalling through BMPR1b . In: Soc. Neurosci. Abs. 677.11 eds. Society for Neuroscience Meeting, San Diego, USA [Details] | |
| (2004) | Society for Neuroscience Meeting, San Diego, USA Toulouse, A., Sullivan, A.M. (2004) Roles of type 1 BMP receptors in the induction of midbrain dopaminergic neurones by GDF5 . In: Soc. Neurosci. Abs. 677.11 eds. Society for Neuroscience Meeting, San Diego, USA [Details] | |
| (2004) | 15th Biennial Meeting of the International Society for Developmental Neuroscience, Edinburgh, Scotland, United Kingdom Shanley, D.K., Sullivan, A.M. (2004) Expression and characterisation of the neuronal cell surface markers 2F7 and E-NCA.M. within the developing rat brain: An in vitro analysis of the development of neuronal restricted precursors . In: Int. J. Dev. Neurosci., Vol. 22 eds. 15th Biennial Meeting of the International Society for Developmental Neuroscience, Edinburgh, Scotland, United Kingdom , pp.601-728 [Details] | |
| (2004) | 4th Forum of European Neuroscience Lisbon Portugal Spitere, K., Sullivan, A.M. (2004) Cellular composition and gene expression in embryonic rat ventral mesencephalic neurosphere cultures . In: FENS Abstr. Vol.2, A107.16 eds. 4th Forum of European Neuroscience Lisbon Portugal [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland Crotty, S.G., Sullivan, A.M., So K.F., Chau, W.K.D., Sharma, A.K., Dockery, P. (2004) Cytoskeletal reorganization in neurons: a stereological approach . In: J. Anat. 205 (60) eds. Anatomical Society of Great Britain and Ireland Summer Meeting 2004, Cork, Ireland [Details] | |
| (2003) | Anatomical Society of Great Britain and Ireland Winter Meeting. Egham, Surrey, United Kingdom O’Keeffe, G.W., Hanke, M., Sullivan, A.M. (2003) Growth/differentiation factor-5, a growth factor with potential for therapeutic approaches to Parkinson’s disease. Oral presentation prize . In: J. Anat. Vol. 203 eds. Anatomical Society of Great Britain and Ireland Winter Meeting. Egham, Surrey, United Kingdom [Details] | |
| (2003) | Journal of Neural Transmission, Supplement Strelau J.;Schober A.;Sullivan A.;Schilling L.;Unsicker E. (2003) Growth/differentiation factor-15 (GDF-15), a novel member of the TGF-ß superfamily, promotes survival of lesioned mesencephalic dopaminergic neurons in vitro and in vivo and is induced in neurons following cortical lesioning Journal of Neural Transmission, Supplement , pp.197-203 [Details] | |
| (2003) | JOURNAL OF NEURAL TRANSMISSION-SUPPLEMENT Strelau, J;Schober, A;Sullivan, A;Schilling, L;Unsicker, K (2003) Growth/differentiation factor-15 (GDF-15), a novel member of the TGF-beta superfamily, promotes survival of lesioned mesencephalic dopaminergic neurons in vitro and in vivo and is induced in neurons following cortical lesioning JOURNAL OF NEURAL TRANSMISSION-SUPPLEMENT , pp.197-203 [Details] | |
| (2003) | International Conference on Alzheimer’s and Parkinson’s Diseases, Seville, Spain Costello, D.J., O'Keeffe, G.W., Hurley, FM, Hanke, M, Sullivan, A.M. (2003) A growth/differentiation factor 5-producing CHO cell line enhances the survival and function of dopaminergic grafts in a 6-OHDA rodent model of Parkinsonism International Conference on Alzheimer’s and Parkinson’s Diseases, Seville, Spain [Details] | |
| (2002) | Anatomical Society of Great Britain and Ireland Summer Meeting, Dublin, Ireland Costello, D.J., O'Keeffe, G.W., Hurley, F.M., Hanke, M., Sullivan, A.M. (2002) Neuroprotective effects of growth / differentiation factor-5 in a rat model of Parkinson's disease . In: J Anat. Vol. 200 (2) eds. Anatomical Society of Great Britain and Ireland Summer Meeting, Dublin, Ireland Dublin, Ireland, [Details] | |
| (2002) | FENS Forum of Neuroscience, Paris. France Wood, T.K., Sullivan, A.M., McDermott, K.W. (2002) In vitro analysis of the effects of the neurotrophins GDF-5, GDNF and glial cells on dopaminergic neurone survival in the ventral mesencephalon . In: FENS Abs eds. FENS Forum of Neuroscience, Paris. France Paris. France, [Details] | |
| (2002) | Anatomical Society of Great Britain and Ireland Summer meeting 2002 Dundee Scotland O’Keeffe, G.W., Costello, D.J., Sullivan, A.M. (2002) Growth/differentiation factor-5: developmental regulator, potential treatment . In: J. Anat eds. Anatomical Society of Great Britain and Ireland Summer meeting 2002 Dundee Scotland Dundee, Scotland, [Details] | |
| (2002) | Anatomical Society of Great Britain and Ireland Summer Meeting, Dublin O’Keeffe, G.W., Sullivan, A.M. (2002) Investigation of the expression of growth/differentiation factor-5 in the developing rat brain. Poster prize . In: J. Anat. 200 (2) 212 eds. Anatomical Society of Great Britain and Ireland Summer Meeting, Dublin Dublin, [Details] | |
| (2002) | Journal of Physiology Paris Krieglstein K.;Strelau J.;Schober A.;Sullivan A.;Unsicker K. (2002) TGF-ß and the regulation of neuron survival and death Journal of Physiology Paris , pp.25-30 [DOI] [Details] | |
| (2002) | FENS Forum of Neuroscience, Paris. France Sullivan, A.M., Hurley FM, Costello D.J. (2002) Restorative effects of growth/differentiation factor-5 (GDF-5) in a rat model of Parkinson's disease . In: FENS eds. FENS Forum of Neuroscience, Paris. France Paris. France, [Details] | |
| (2002) | Glia Wood, T.K., Sullivan, A.M., McDermott, K.W. (2002) In vitro analysis of astroglial-neuronal interactions in the ventral mesencephlon . In: Glia eds. Glia [Details] | |
| (2002) | Anatomical Society of Great Britain and Ireland Summer Meeting, Dublin, Ireland Wood, T.K., Sullivan, A.M., McDermott, K.W. (2002) Antimitotic treatment to achieve neurone enriched ventral mesencephalic cultures for studies of neurotrophins . In: J Anat. 200 (2) eds. Anatomical Society of Great Britain and Ireland Summer Meeting, Dublin, Ireland Dublin, Ireland, [Details] | |
| (2002) | In vitro analysis of astroglial-neuronal interactions in the ventral mesencephalon Wood, TK,Sullivan, AM,McDermott, KW (2002) GLIA In vitro analysis of astroglial-neuronal interactions in the ventral mesencephalon , pp.37-37 [Details] | |
| (2002) | Biochem. Soc O’Keeffe, G.W., Crotty, S.G., Dockery, P., Sullivan, A.M. (2002) The type of cell death induced by MPP+ is both concentration-and time-dependent . In: Biochem. Soc. Trans. 29 (5), 117 eds. Biochem. Soc [Details] | |
| (2002) | Anatomical Society of Great Britain and Ireland Summer Meeting, Dublin, Ireland Costello, D.J., Hurley, F.M., Sullivan, A.M. (2002) Growth/differentiation factor-5 enhances graft survival and reverses motor asymmetry in a rat model of Parkinson's disease . In: J Anat. Vol. 200 (2) eds. Anatomical Society of Great Britain and Ireland Summer Meeting, Dublin, Ireland Dublin, Ireland, [Details] | |
| (2000) | FENS Forum of Neuroscience, Brighton, UK Wood, T.K., Sullivan, A.M., McDermott, K.W. (2000) Glia-depleted mesencephalic cultures for investigation of the action of the dopaminergic neurotrophin GDF-5 . In: Eur. J. Neurosci. 12, Suppl. 11 eds. FENS Forum of Neuroscience, Brighton, UK Brighton, UK, [Details] | |
| (1997) | Society for Neuroscience meeting, New Orleans, USA Sullivan, A.M., Opacka-Juffry J, Hotten G, Pohl J, Blunt S.B. (1997) Growth/differentiation factor 5 protects nigrostriatal dopaminergic neurones in a rat model of Parkinson’s disease . In: Soc. Neurosci. Abs. 23, p622 eds. Society for Neuroscience meeting, New Orleans, USA New Orleans, USA, [Details] | |
| (1997) | Movement Disorders Sullivan, A.M., Opacka-Juffry, J., Blunt, S.B. (1997) Long-term protection of the rat nigrostriatal dopaminergic system by GDNF in vivo . In: Movement Disorders Vol 12, p157 eds. Movement Disorders [Details] | |
| (1997) | British Neuroscience Association meeting Sullivan, A.M., Opacka-Juffry, J., Blunt, S.B. (1997) Long-term protection of the rat nigrostriatal dopaminergic system by GDNF in vivo . In: Brain Res. Assoc. Abs. Vol. 14 eds. British Neuroscience Association meeting [Details] | |
| (1995) | British Neuroscience Association meeting Sullivan, A.M., Morton A.J. (1995) Induction of Fos protein in organotypic cultures of rat cerebellum by endothelins . In: Brain Res. Assoc. Abs. Vol. 12 eds. British Neuroscience Association meeting [Details] | |
| (1994) | British Neuroscience Association meeting Sullivan, A.M., Morton A.J. (1994) Glutamate-induced expression of Fos protein by granule cells in organotypic cultures of rat cerebellum . In: Brain Res. Assoc. Abs. Vol. 11 eds. British Neuroscience Association meeting [Details] | |
| (1994) | British Neuroscience Association meeting Sullivan, A.M., Morton A.J. (1994) Is the development of Purkinje cell dendrites in organotypic culture of rat cerebellum dependent on granule cells? . In: Brain Res. Assoc. Abs. Vol. 11 eds. British Neuroscience Association meeting [Details] |
Abstract
| Year | Publication | |
|---|---|---|
| (2020) | Sleep and Depression in Parkinson's Disease: Investigating the Relationship between Sleep and Depression Using a Combination of Subjective and Objective Sleep Assessment Methods. Mulryan, P;Affonso, S;Sullivan, A (2020) Sleep and Depression in Parkinson's Disease: Investigating the Relationship between Sleep and Depression Using a Combination of Subjective and Objective Sleep Assessment Methods. HOBOKEN: Abstract [Details] | |
| (2017) | Investigation of the brain gut axis in the rAAV-alpha-synuclein PD model: Reveals enteric nervous system pathology and alterations in the gut microbiome. O'Donovan, S;Crowley, EK;Browne, J;O'Sullivan, O;O'Leary, OF;Timmons, S;Nolan, YM;O'Toole, PW;Clarke, DJ;Hyland, NP;Joyce, SA;Sullivan, AM;O'Neill, C (2017) Investigation of the brain gut axis in the rAAV-alpha-synuclein PD model: Reveals enteric nervous system pathology and alterations in the gut microbiome. HOBOKEN: Abstract [Details] | |
| (2016) | Canonical BMP-SMAD Signalling Promotes Neurite Growth in Embryonic Rat Midbrain Dopaminergic Neurons. Hegarty, SV;Collins, LM;Gavin, AM;Roche, SL;Wyatt, SL;Sullivan, AM;O'Keeffe, GW (2016) Canonical BMP-SMAD Signalling Promotes Neurite Growth in Embryonic Rat Midbrain Dopaminergic Neurons. LONDON: Abstract [Details] | |
| (2016) | Novel neurotrophic strategy: interrogation of intracellular molecules regulating growth of midbrain dopaminergic neurons. Hegarty, S;O'Leary, E;Wyatt, S;Sullivan, A;O'Keeffe, G (2016) Novel neurotrophic strategy: interrogation of intracellular molecules regulating growth of midbrain dopaminergic neurons. AMSTERDAM: Abstract [Details] | |
| (2016) | Novel neurotrophic strategy: interrogation of intracellular molecules regulating growth of midbrain dopaminergic neurons. Hegarty, SV;O'Leary, E;Solger, F;Wyatt, SL;Sullivan, AM;O'Keeffe, GW (2016) Novel neurotrophic strategy: interrogation of intracellular molecules regulating growth of midbrain dopaminergic neurons. AMSTERDAM: Abstract [Details] | |
| (2011) | SPATIOTEMPORAL ANALYSIS OF GDF-5 EXPRESSION IN THE DEVELOPING RAT NIGROSTRIATAL SYSTEM. Gavin, AM;Wyatt, S;Sullivan, AM;O'Keeffe, GW (2011) SPATIOTEMPORAL ANALYSIS OF GDF-5 EXPRESSION IN THE DEVELOPING RAT NIGROSTRIATAL SYSTEM. LONDON: Abstract [Details] | |
| (2011) | STEREOLOGICAL ANALYSIS OF THE BRACHYPOD MOUSE BRAIN. Crampton, S;Sullivan, A;O'Keeffe, G (2011) STEREOLOGICAL ANALYSIS OF THE BRACHYPOD MOUSE BRAIN. LONDON: Abstract [Details] | |
| (2010) | EFFECTS OF TUMOUR NECROSIS FACTOR-A ON PROLIFERATION AND DIFFERENTATION OF EMBRYONIC RAT HIPPOCAMPAL NEURAL PRECURSOR CELLS: A ROLE FOR HES1. Ryan, S;Keohane, A;Maloney, E;Sullivan, AM;Nolan, Y (2010) EFFECTS OF TUMOUR NECROSIS FACTOR-A ON PROLIFERATION AND DIFFERENTATION OF EMBRYONIC RAT HIPPOCAMPAL NEURAL PRECURSOR CELLS: A ROLE FOR HES1. LONDON: Abstract [Details] | |
| (2008) | The effects of the pro-intlanumatory cytokine TNF-alpha on the proliferation and differentiation of embryonic rat hippocampal neural precursor cells. Keohanc, A;Sullivan, AM;Nolan, Y (2008) The effects of the pro-intlanumatory cytokine TNF-alpha on the proliferation and differentiation of embryonic rat hippocampal neural precursor cells. AMSTERDAM: Abstract [Details] | |
| (2008) | IL-1 beta released from LPS-stimulated cortical glial cultures exacerbates 6-OHDA-induced dopaminergic neuronal cell death in vitro. Long, CM;Sullivan, AM;Nolan, Y (2008) IL-1 beta released from LPS-stimulated cortical glial cultures exacerbates 6-OHDA-induced dopaminergic neuronal cell death in vitro. AMSTERDAM: Abstract [Details] | |
| (2002) | In vitro analysis of astroglial-neuronal interactions in the ventral mesencephalon. Wood, TK;Sullivan, AM;McDermott, KW (2002) In vitro analysis of astroglial-neuronal interactions in the ventral mesencephalon. NEW YORK: Abstract [Details] |
Editorship
| Year | Publication | |
|---|---|---|
| (2021) | Neuronal Signaling: A reflection on the Biochemical Society's newest journal and an exciting outlook on its next steps. Sullivan AM;Stanford SC; (2021) Neuronal Signaling: A reflection on the Biochemical Society's newest journal and an exciting outlook on its next steps. Editorship [DOI] [Details] | |
| (2020) | Editorial: The Role of Stem Cells, Epigenetics and MicroRNAs in Parkinson's Disease. Hegarty S.V.;Green H.F.;Niclis J.;O'Keeffe G.W.;Sullivan A.M. (2020) Editorial: The Role of Stem Cells, Epigenetics and MicroRNAs in Parkinson's Disease. Editorship [DOI] [Details] | |
| (2017) | Neuronal Signaling: an introduction. Sullivan, A.M. (2017) Neuronal Signaling: an introduction. Editorship [DOI] [Details] | |
| (2005) | Symposium on ‘Neural stem and progenitor cells: biology and clinical potential’, part two. Sullivan AM, McDermott KW, Butt A, Fraher J (2005) Symposium on ‘Neural stem and progenitor cells: biology and clinical potential’, part two. Editorship [DOI] [Details] | |
| (2005) | Symposium on ‘Neural stem and progenitor cells: biology and clinical potential’ Part 1. Butt A, Sullivan A, McDermott KW, Fraher J (2005) Symposium on ‘Neural stem and progenitor cells: biology and clinical potential’ Part 1. Editorship [DOI] [Details] |
Book Chapters
| Year | Publication | |
|---|---|---|
| (2011) | 'The potential of neurotrophic factors in the treatment of Parkinson’s disease' Sullivan, A.M. and Toulouse, A. (2011) 'The potential of neurotrophic factors in the treatment of Parkinson’s disease' In: David I. Finkelstein (eds). Parkinson's Disease / Book 4. Croatia: InTech. [DOI] [Details] |
Unpublished work
| Year | Publication | |
|---|---|---|
| (2014) | Sympathetic innervation depends on target-derived growth differentiation factor 5. O’Keeffe, G.W., Gutierrez, H., Laurie, C., Osorio, C., Sullivan, A.M. Gavaldà, N. Wyatt, S.L., Davies, A.M. (2014) Sympathetic innervation depends on target-derived growth differentiation factor 5. Unpublished work [Details] | |
| (2014) | Smad-interacting protein 1 (Sip1) is a novel regulator of the development of ventral midbrain dopaminergic neurons. Hegarty, S.V., Wyatt, S.L., Sullivan, A.M., O'Keeffe, G.W (2014) Smad-interacting protein 1 (Sip1) is a novel regulator of the development of ventral midbrain dopaminergic neurons. Unpublished work [Details] | |
| (2014) | Neurotrophic and neuroprotective effects of class-specific Histone deacetylase (HDAC) inhibitors in cellular models of Parkinson’s disease. Collins, L.M., Adriaanse, L., Hegarty, S.V., Sullivan A.M, O’Keeffe, G.W. (2014) Neurotrophic and neuroprotective effects of class-specific Histone deacetylase (HDAC) inhibitors in cellular models of Parkinson’s disease. Unpublished work [Details] | |
| (2014) | Mood disorders and cognitive dysfunction in Parkinson’s disease: role of alpha-synuclein transmission. Kelly, M.J., O’Keeffe, G.W., Sullivan, A.M (2014) Mood disorders and cognitive dysfunction in Parkinson’s disease: role of alpha-synuclein transmission. Unpublished work [Details] | |
| (2014) | Cognitive dysfunction in alpha-synuclein animal models of Parkinson’s disease. Dolan, E. Nolan, Y.M., Sullivan, A.M. (2014) Cognitive dysfunction in alpha-synuclein animal models of Parkinson’s disease. Unpublished work [Details] | |
| (2014) | Pain in Parkinson’s disease: Relevance of gut to brain signalling. Felice, V.D., Quigley, E.M. Sullivan, A.M, O’Sullivan, S., O’Keeffe, G.W., O’Mahony, S.M. (2014) Pain in Parkinson’s disease: Relevance of gut to brain signalling. Unpublished work [Details] | |
| (2014) | Differential requirement for dynamin-dependent endocytosis by bone morphogenetic proteins in the promotion of neurite growth in a model of human midbrain dopaminergic neurons. Hegarty, S.V., Sullivan, A.M.*, O'Keeffe, G.W.* (JOINT SENIOR AUTHOR) (2014) Differential requirement for dynamin-dependent endocytosis by bone morphogenetic proteins in the promotion of neurite growth in a model of human midbrain dopaminergic neurons. Unpublished work [Details] | |
| (2014) | The role of Nociceptin/Orphanin FQ in the development of midbrain dopaminergic neurons. Dal Bo, G. Collins, L.M., Sullivan, A.M., Morari, M., O’Keeffe, G.W. (2014) The role of Nociceptin/Orphanin FQ in the development of midbrain dopaminergic neurons. Unpublished work [Details] |
Professional Activities
Education
| Year | Institution | Qualification | Subject | |
|---|---|---|---|---|
| 2005 | University College Cork | Postgraduate Certificate in Teaching and Learning in Higher Ed. | Teaching and Learning in Higher Education | |
| 1995 | University of Cambridge | PhD | Neuropharmacology | |
| 1992 | University College Dublin | BSc | Pharmacology |
Professional Associations
| Association | Function | From / To | |
|---|---|---|---|
| Federation of European Neuroscience Societies | Member | / | |
| Network of European Cerebral Transplantation and Repair | Member | / | |
| Neuroscience Ireland | Member | / | |
| Irish Institute of Clinical Neuroscience | Member | / |
Employment
| Employer | Position | From / To | |
|---|---|---|---|
| University College Cork | Senior Lecturer | 01-OCT-98 / | |
| University College Cork | College Lecturer | 01-OCT-98 / 30-SEP-06 | |
| Imperial College London | Post-doctoral researcher | 01-OCT-95 / 30-SEP-98 |
Honours and Awards
| Year | Title | Awarding Body | |
|---|---|---|---|
| 2013 | Neuroscience Ireland Conference, Cork. Prize for Best Poster | Neuroscience Ireland | |
| 2012 | Neuroscience Ireland Conference, Dublin. Prize for Best Poster. | Neuroscience Ireland | |
| 2010 | Certificate in Peer-Mentoring (Distinction) | FETAC | |
| 2007 | British Neuroscience Association meeting, Harrogate, UK. Prize for Best Poster. | British Neuroscience Association | |
| 2006 | Royal Academy of Medicine in Ireland Biomedical Section Winter Meeting, Dublin. Prize for Best Poster. | Royal Academy of Medicine in Ireland | |
| 2005 | International Congress on Parkinson’s Disease and Related Disorders, Berlin, Germany. Prize for Best Poster. | International Congress on Parkinson’s Disease and Related Disorders | |
| 2003 | Anatomical Society of Great Britain and Ireland Winter Meeting, UK. Oral presentation prize. | Anatomical Society of Great Britain and Ireland | |
| 2002 | Anatomical Society of Great Britain and Ireland Summer Meeting, Dublin. Prize for Best Poster. | Anatomical Society of Great Britain and Ireland |
Journal Activities
| Journal | Role | To / From | |
|---|---|---|---|
| Editor | - | ||
| Behavioural Brain Research | Referee | - | |
| Biomedcentral Neuroscience | Referee | - | |
| Biomedicine And Biotechnology | Referee | - | |
| Bioscience Reports | Referee | - | |
| Brain Research | Referee | - | |
| Brain Research Bulletin | Referee | - | |
| Cns Neuroscience And Therapeutics | Referee | - | |
| Current Stem Cell Research And Therapy | Referee | - | |
| Cytotherapy | Referee | - | |
| European Journal Of Neuroscience | Referee | - | |
| Experimental Neurology | Referee | - | |
| International Journal Of Molecular Sciences | Referee | - | |
| International Journal Of Neuroscience | Referee | - | |
| Journal Of Anatomy | Referee | - | |
| Journal Of Anatomy | Editor | - | |
| Journal Of Biomaterials And Tissue Engineering | Referee | - | |
| Journal Of Cell And Molecular Biology | Referee | - | |
| Journal Of Neural Transmission | Referee | - | |
| Journal Of Neurodegenerative Diseases | Referee | - | |
| Journal Of Neuroscience | Referee | - | |
| Journal Of Neuroscience Methods | Referee | - | |
| Journal Of Neuroscience Research | Referee | - | |
| Molecular Therapy | Referee | - | |
| Neural Regeneration Research | Referee | - | |
| Neurobiology Of Disease | Referee | - | |
| Neuronal Signaling | Referee | - | |
| Neuropharmacology | Referee | - | |
| Neuropsychobiology | Referee | - | |
| Neuroreport | Referee | - | |
| Neuroreport | Member of Editorial Board | - | |
| Neuroscience | Referee | - | |
| Neuroscience Letters | Referee | - | |
| Neurotoxicology | Referee | - | |
| Neurotoxicity Research | Referee | - | |
| Parkinson’S Disease | Referee | - | |
| Parkinsonism & Related Disorders | Referee | - | |
| Physiology And Behaviour | Referee | - | |
| Science | Referee | - | |
| Science Signaling | Referee | - | |
| Scientific Reports | Referee | - | |
| Stem Cell Research And Therapy | Referee | - | |
| Stem Cell Reviews And Reports | Referee | - |
Committees
| Committee | Function | From / To | |
|---|---|---|---|
| Fulbright Commission, Ireland. Panel Member. | Science and Technology Scholarship Awards Reviewer | 2014 / | |
| ERASMUS Scheme | Departmental Co-ordinator | 2004 / | |
| NECTAR International Conference. Organising Committee. | Committee Member | 2014 / 2014 | |
| First Irish Parkinson's Disease Meeting | Organiser | 2013 / 2013 | |
| Neuroscience Ireland Conference. Organising Committee. | Committee Member | 2013 / 2013 | |
| Cork NeuroScience Group | Secretary | 2010 / | |
| Health Research Board, Ireland. Postdoctoral Fellowship Scheme Grant Reviewer 2009-2010 | Grant Reviewer | 2009 / 2010 | |
| Anatomical Society of Great Britain and Ireland. Elected Council Member 2006 - 2009 | Council member | 2006 / 2009 | |
| Neuroscience Ireland Conference. Organising Committee. | Committee Member | 2006 / 2006 | |
| College of SEFS Board of Studies for CK402 degree | Committee Member | 2014 / | |
| National University of Ireland. Grant Reviewer 2006 - current | Grant Reviewer | 2006 / | |
| Wellcome Trust, London. Grant Reviewer 2006 - current | Grant reviewer | 2006 / | |
| Medical Research Council, London. Grant Reviewer 2006 - current | Grant reviewer | 2006 / | |
| Anatomical Society of Great Britain and Ireland. Grant Reviewer 2005 - 2010 | Grant Reviewer | 2005 / 2009 | |
| Health Research Board, Ireland. Neuroscience Clinical Neurology and Mental Health Grant Review Panel 2005-2008 | Grant Reviewer | 2005 / 2008 | |
| Irish Network of Neural Stem Cell Investigators | Committee member | 2004 / 2008 | |
| Parkinson's UK, London. Grant Reviewer 2004-current | Grant Reviewer | 2004 / | |
| Anatomical Society of Great Britain and Ireland Conference. Organising Committee. | Committee Member | 2004 / 2004 | |
| UCC International Education Office | Departmental Representative | 2004 / | |
| College of SEFS Academic Programmes and Curriculum Development Committee | Committee Member | 2002 / | |
| Curriculum Committee for BSc Neuroscience | Chair | 1998 / | |
| Disability Support Service | Departmental Representative | 1999 / 2005 | |
| Department of Anatomy and Neuroscience Graduate Studies Committee | Chair | 1999 / 2007 |
Outreach Activities
| Description | |
|---|---|
NEUROSCIENCE OUTREACH ACTIVITIES BY POSTGRADUATES
| |
SCHOOL LIAISON ACTIVITIES
| |
PUBLIC AWARENESS OF PARKINSON’S DISEASE AND NEURODEGENERATIVE DISORERS
|
Other Activities
| Description | |
|---|---|
External Examiner, MSc in Stem Cells and Regeneration. Bristol University, UK. (2013-2018) | |
External Examiner for PhD thesis. Trinity College Dublin, Dept. of Physiology. 2012. | |
External Examiner for PhD thesis. Trinity College Dublin, Dept. of Biochemistry. 2011. | |
External Examiner for PhD thesis. National University of Ireland Galway, Dept. of Biochemistry. 2009. | |
External Examiner for PhD thesis. Edinburgh University. 2007. | |
External Examiner for PhD thesis. Trinity College Dublin, Dept. of Physiology. 2007. | |
External Examiner for PhD thesis. Cardiff University, School of Biosciences. 2005. | |
External Examiner for PhD thesis. Trinity College Dublin, Dept. of Physiology. 2003. | |
External Examiner in Anatomy for the Membership of the Faculty of Dental Surgeons (MFDS/MFD), Royal College of Surgeons in Ireland. (2001-2007) | |
External Examiner in Pharmacology for examinations for non-EEA-trained dentists, Dental Council of Ireland. (2000-2006). |
Languages
| Language | Reading | Writing | Speaking | |
|---|---|---|---|---|
| French | Functional | Functional | Functional | |
| English | Fluent | Fluent | Fluent | |
| Irish | Functional | Functional | Functional |
Conference Contributions
| Year | Publication | |
|---|---|---|
| (2017) | AD/PDTM 2017, O’Donovan SM, Crowley E, Browne J, O’Sullivan O, O’Leary OF, Timmons S, Nolan YM, O’Toole PW, Clarke DJ, Hyland NP, Joyce SA, Sullivan AM, O’Neill C (2017) The brain ↔gut axis in Parkinson’s disease: defining gut pathology and the impact of exercise in the rAAV-α-synuclein rat model of PD AD/PDTM 2017, the 13th International Conference on Alzheimer's and Parkinson's Diseases and Related Neurological Disorders. [Invited Lectures (Conference)], AD/PDTM 2017, Vienna,Austria . [Details] | |
| (2017) | Neurogastroenterology and Motiltiy, S O'Donovan, EK Crowley, J Browne, O O'Sullivan, OF O'Leary, S Timmons, YM Nolan, PW O'Toole, DJ Clarke, NP Hyland, SA Joyce, AM Sullivan, C O'Neill (2017) Investigation of the brain gut axis in the rAAV-alpha-synuclein PD model: Reveals enteric nervous system pathology and alterations in the gut microbiome. [Poster Presentation], Neurogastroenterology and Motiltiy, Cork Ireland . [Details] | |
| (2017) | AD/PDTM 2017, O’Donovan SM, Crowley E, Browne J, O’Sullivan O, O’Leary OF, Timmons S, Nolan YM, O’Toole PW, Clarke DJ, Hyland NP, Joyce SA, Sullivan AM, O’Neill C (2017) The brain ↔gut axis in Parkinson’s disease: defining gut pathology and the impact of exercise in the rAAV-α-synuclein rat model of PD AD/PDTM 2017, the 13th International Conference on Alzheimer's and Parkinson's Diseases and Related Neurological Disorders. [Poster Presentation], AD/PDTM 2017, Vienna,Austria . [Details] | |
| (2017) | Neuroscience Ireland, SM O’Donovan, EK Crowley, J Browne, O O’Sullivan, OF O’Leary, S Timmons, YM Nolan, PW O’Toole, DJ Clarke, NP Hyland, SA Joyce, AM Sullivan, C O’Neill (2017) Investigation of the brain gut axis in the rAAV-alpha-synuclein PD model: Reveals enteric nervous system pathology and alterations in the gut microbiome. [Poster Presentation], Neuroscience Ireland, NUI Galway , 24-AUG-17. [Details] | |
| (2016) | HEC 2016: The Scholarship of Teaching, Learning and Organising, O'Mahony, C., Higgs, B. and O'Sullivan, A. (2016) Building institutional capacity for a whole programme approach to undergraduate research. [Oral Presentation], HEC 2016: The Scholarship of Teaching, Learning and Organising, Amsterdam , 13-JUL-16 - 15-JUL-16. [Details] | |
| (2014) | Molecular Medicine Ireland Education and Training Annual Scientific Meeting, Dolan, E. Nolan, Y.M., Sullivan, A.M. (2014) Characterisation of cognitive deficits in an alpha-synuclein model of Parkinson’s disease. [Invited Lectures (Conference)], Molecular Medicine Ireland Education and Training Annual Scientific Meeting, Trinity College Dublin . [Details] | |
| (2014) | EURON workshop: New Targets in Neurodegenerative Diseases, Dolan, E. Nolan, Y.M., Sullivan, A.M. (2014) Motor effects of unilateral and bilateral lesions induced by viral vector-mediated overexpression of alpha-synuclein in a rodent model of Parkinson’s disease. [Invited Lectures (Conference)], EURON workshop: New Targets in Neurodegenerative Diseases, Braga, Portugal . [Details] | |
| (2014) | Molecular Medicine Ireland Education and Training Annual Scientific Meeting, Dolan, E. Nolan, Y.M., Sullivan, A.M. (2014) Cognitive dysfunction in alpha-synuclein animal models of Parkinson’s disease. [Invited Lectures (Conference)], Molecular Medicine Ireland Education and Training Annual Scientific Meeting, Trinitry College Dublin . [Details] | |
| (2013) | 8th Neuroscience Ireland Conference, Hegarty, S.V., Sullivan, A.M., O'Keeffe G.W. (2013) BMP2 and GDF5 induce neuronal differentiation through a Smad dependant pathway in a model of human midbrain dopaminergic neurons. Prize for best poster. [Poster Presentation], 8th Neuroscience Ireland Conference, Cork, Ireland , 03-SEP-13 - 05-SEP-13. [Details] | |
| (2011) | 8th IBRO World Congress of Neuroscience, O’Brien, I., Sullivan, A.M., Nolan, Y.M., Toulouse, A. (2011) Expression of the 2F7 epitope in the rat embryo, and adult brain. [Invited Lectures (Conference)], 8th IBRO World Congress of Neuroscience, Florence, Italy , 14-JUL-11 - 18-JUL-11. [Details] | |
| (2010) | Neuroscience Ireland Conference, Dublin, Ryan, S., Keohane, A., Maloney, E., Sullivan, A.M., Nolan, Y. (2010) Effects of TNF-alpha on proliferation and differentiation of embryonic rat hippocampal neural precursor cells: a role for Hes1. [Invited Lectures (Conference)], Neuroscience Ireland Conference, Dublin, Ireland . [Details] | |
| (2010) | Neuroscience Ireland Conference, Dublin, Ryan, S., Keohane, A., Maloney, E., Sullivan, A.M., Nolan, Y. (2010) Effects of tumour necrosis factor-a on proliferation and differentation of embryonic rat hippocampal neural precursor cells: a role for HES1. [Invited Lectures (Conference)], Neuroscience Ireland Conference, Dublin, Ireland . [Details] | |
| (2009) | International conference on Alzheimer's and Parkinson's diseases, Long, C., Sullivan, A.M., Nolan, Y. (2009) The effect of pharmacological and endogenous p38 inhibition on 6-hydroxydopamine-treated rat ventral mesencephalic neurons in vitro. [Invited Lectures (Conference)], International conference on Alzheimer's and Parkinson's diseases, Prague, Czech Republic . [Details] | |
| (2008) | International Neuroimmunology Symposium, Dublin, Long, C., Sullivan, A.M., Nolan, Y. (2008) IL-1β released from LPS-stimulated cortical glial cultures exacerbates 6-OHDA-induced dopaminergic neuronal cell death in vitro. [Invited Lectures (Conference)], International Neuroimmunology Symposium, Dublin, Ireland . [Details] | |
| (2008) | 2nd Neuroscience Ireland Conference, NUI Galway, Keohane, A., Sullivan, A.M., Nolan, Y. (2008) IL-1 receptor antagonist prevents the effects of the pro-inflammatory cytokine, IL-1β on differentiating embryonic rat hippocampal neuronal precursor cells. [Invited Lectures (Conference)], 2nd Neuroscience Ireland Conference, NUI Galway, Ireland . [Details] | |
| (2008) | Neuroscience Ireland Conference, Galway, Ryan, S., Maloney, E., Keohane, A., Sullivan, A.M., Nolan, Y.M. (2008) TNF-a affects the proliferation and differentiation of embryonic rat hippocampal neural precursor cells. [Invited Lectures (Conference)], Neuroscience Ireland Conference, Galway, Ireland . [Details] | |
| (2008) | International Neuroimmunology Symposium, Dublin, Long, C., Sullivan, A.M., Nolan, Y. (2008) Il-1 Beta Released From Lps-Stimulated Cortical Glial Cultures Exacerbates 6-Ohda-Induced Dopaminergic Neuronal Cell Death In Vitro. [Invited Lectures (Conference)], International Neuroimmunology Symposium, Dublin, Ireland . [Details] | |
| (2008) | International Neuroimmunology Symposium, Dublin, Ireland, Keohane, A., Sullivan, A.M., Nolan, Y. (2008) The effect of the pro-inflammatory cytokine, TNFα, on the proliferation and differentiation of embryonic hippocampal neural cells. [Invited Lectures (Conference)], International Neuroimmunology Symposium, Dublin, Ireland, Ireland . [Details] | |
| (2008) | Neuroscience Ireland Conference, Galway, Long, C., Sullivan, A.M., Nolan, Y. (2008) The role of IL-1b in mediating the effects of LPS-stimulated rat glia on dopaminergic neuronal death in vitro. [Invited Lectures (Conference)], Neuroscience Ireland Conference, Galway, Ireland . [Details] | |
| (2007) | XVIIth World Federation of Neurology World Congress on Parkinson's Disease and Related Disorders, Amsterdam, Long, C., Sullivan, A.M., Nolan, Y. (2007) The effect of p38 inhibition on the survival of 6-hydroxydopamine-treated rat ventral mesencephalic neurons in vitro. [Invited Lectures (Conference)], XVIIth World Federation of Neurology World Congress on Parkinson's Disease and Related Disorders, Amsterdam, Netherlands . [Details] | |
| (2007) | British Neuroscience Association meeting, Harrogate, UK. Brit. Neurosci. Assoc, Long, C., Sullivan, A.M., Nolan, Y; (2007) The effect of conditioned media from LPS-stimulated rat mixed glial cultures on 6-OHDA-treated rat ventral mesencephalic neurons in vitro. Prize for Best Poster. [Invited Lectures (Conference)], British Neuroscience Association meeting, Harrogate, UK. Brit. Neurosci. Assoc, UK . [Details] | |
| (2007) | British Neuroscience Association Meeting, Keohane, A., Sullivan, A.M., Nolan, Y. (2007) The effect of pro-inflammatory cytokines, IL-1β and TNFα on embryonic rat hippocampal neuronal precursor cells. [Invited Lectures (Conference)], British Neuroscience Association Meeting, UK . [Details] | |
| (2006) | New Horizon's in Medical Research, Keohane, A., Sullivan, A.M., Nolan, Y. (2006) Characterisation of embryonic rat hippocampal neuronal precursor cells in neurosphere cultures. [Invited Lectures (Conference)], New Horizon's in Medical Research, Cork . [Details] | |
| (2006) | Neuroscience Ireland Meeting, Cork, Long, C., Sullivan, A.M., Nolan, Y. (2006) 6-hydroxydopamine induces a direct neurotoxic effect on embryonic rat midbrain dopaminergic neurons independent of microglial activation in vitro. [Invited Lectures (Conference)], Neuroscience Ireland Meeting, Cork, Ireland . [Details] | |
| (2006) | Society for Neuroscience meeting, Atlanta, USA, Crotty,S., Fitzgerald, P., Mandel,A.,Bolton, A.E., Sullivan, A.M., Nolan, Y. (2006) Treatment with a novel phospholipid-based drug formulation prevents behavioural deficits induced by proteasome inibition: implications for Parkinson's disease. [Invited Lectures (Conference)], Society for Neuroscience meeting, Atlanta, USA, Atlanta, USA . [Details] | |
| (2006) | FENS Forum of Neuroscience, Vienna, Austria, Long, C., Sullivan, A.M., Nolan, Y. (2006) 6-hydroxydopamine induces a direct neurotoxic effect on embryonic rat midbrain dopaminergic neurons independent of microglial activation in vitro. [Invited Lectures (Conference)], FENS Forum of Neuroscience, Vienna, Austria, Vienna, Austria . [Details] | |
| (2006) | Royal Academy of Medicine in Ireland Biomedical Section Winter Meeting, Dublin, Long, C., Nolan, Y.M., Sullivan, A.M. (2006) Effects of 6-hydroxydopamine on the survival of embryonic rat midbrain dopamine neurons in vitro. Poster Prize. [Invited Lectures (Conference)], Royal Academy of Medicine in Ireland Biomedical Section Winter Meeting, Dublin, Ireland . [Details] | |
| (2006) | Royal Academy of Medicine in Ireland Biomedical Section Meeting, Dublin, Crotty, S., Fitzgerald, P., Harris, D.M., Fisher, A., Mandel, A., Bolton, A.E., Sullivan, A.M., Nolan, Y. (2006) 6-hydroxydopamine-induced p38 activation in rat nigral dopaminergic neurons is reduced by treatment with a novel phospholipid-based drug formulation. [Invited Lectures (Conference)], Royal Academy of Medicine in Ireland Biomedical Section Meeting, Dublin, Ireland . [Details] | |
| (2005) | Society for Neuroscience meeting, Washington, USA, O’Sullivan, D.B., Harrison, P.T., Nolan, Y.M., Sullivan, A.M. (2005) Prevention of apoptosis in cultured dopaminergic neurons by GDNF and GDF5. [Invited Lectures (Conference)], Society for Neuroscience meeting, Washington, USA, Washington DC, USA , 12-NOV-05 - 16-NOV-05. [Details] | |
| (2005) | Royal Academy of Medicine in Ireland Biomedical Section Meeting, Dublin, Fitzgerald, P., Harris, D.M., Crotty, S., Fisher, A., Mandel, A., Bolton, A.E., Sullivan, A.M., Nolan, Y.M. (2005) 6-hydroxydopamine-induced degeneration of rat nigral dopaminergic neurons and microglial activation is reduced by treatment with a novel phospholipid-based drug formulation. [Invited Lectures (Conference)], Royal Academy of Medicine in Ireland Biomedical Section Meeting, Dublin, Ireland . [Details] | |
| (2005) | International Congress on Parkinson’s Disease and Related Disorders, Berlin, Germany, Harris, D.M., Fisher, A., Mandel, A., Bolton, A.E., Sullivan, A.M., Nolan, Y. (2005) 6-hydroxydopamine-induced degeneration of rat nigral dopaminergic neurons and microglial activation is reduced by treatment with a novel phospholipid-based drug formulation. [Invited Lectures (Conference)], International Congress on Parkinson’s Disease and Related Disorders, Berlin, Germany, Berlin, Germany , 05-JUN-05 - 08-JUN-06. [Details] | |
| (2005) | Society for Neuroscience meeting, Washington, USA, Fitzgerald, P., Harris, D.M., Crotty, S., Harkin, A., Mandel, A., Bolton, A.E., Sullivan, A.M., Nolan, Y. (2005) Treatment with a novel phospholipid-based drug formulation inhibits 6-hydroxydopamine-induced p38 activation in rat substantia nigra. [Invited Lectures (Conference)], Society for Neuroscience meeting, Washington, USA, Washington DC, USA , 11-DEC-05 - 16-NOV-05. [Details] | |
| (2004) | Society for Neuroscience Meeting, San Diego, USA, Fisher, A., Harris, D.M., Harkin, A.J., Bolton, A.E., Sullivan, A.M., Nolan Y.M. (2004) Novel phospholipid-based drug formulation retards the 6-hydroxydopamine-induced degeneration of rat nigral dopaminergic neurons. [Invited Lectures (Conference)], Society for Neuroscience Meeting, San Diego, USA, San Diego, USA . [Details] | |
| (2002) | 3rd Forum of European Neuroscience, O’Keeffe, G.W., Costello, D.J., Sullivan, A.M. (2002) Restorative effects of growth/differentiation factor-5 (GDF-5) in a rat model of Parkinson's disease. [Poster Presentation], 3rd Forum of European Neuroscience, Paris, France , 13-JUL-02 - 17-JUL-02. [Details] | |
| (2012) | 7th Neuroscience Ireland Conference, Walsh S, Keeshan K, Nolan Y, O’Keeffe GW, Sullivan AM. (2012) The effect of IL-1R1 shRNA intra-nigral administration in a hemi-parkinsonian 6-hydroxydopamine rat model. [Poster Presentation], 7th Neuroscience Ireland Conference, Dublin, Ireland , 05-SEP-12 - 06-SEP-12. [Details] | |
| (2012) | 7th Neuroscience Ireland Conference, Collins LM, O'Keeffe GW, Long-Smith CM, Sullivan AM, Toulouse A, Nolan YM. (2012) Mitogen-activated protein kinase phosphatase (MKP)-1 promotes the morphological development of midbrain dopmainergic neurons. [Poster Presentation], 7th Neuroscience Ireland Conference, Dublin, Ireland , 05-SEP-12 - 05-SEP-12. [Details] | |
| (2013) | Young Life Scientists Conference 2013, Hegarty, S.V., Sullivan, A.M., O'Keeffe G.W. (2013) BMP2 and GDF5 induce neurite extension in ventral midbrain dopaminergic neurons through a Smad dependent pathway. [Oral Presentation], Young Life Scientists Conference 2013, UCC, Cork , 11-SEP-13 - 11-SEP-13. [Details] | |
| (2013) | 8th Neuroscience Ireland Conference 2013, Collins, L.M., O'Keeffe, G.W., Gavin, A.M., Wyatt, S.L., Sullivan, A.M., Toulouse, A., Nolan, Y.M. (2013) Expression of endogenous MKP-1 in the adult rat nigrostriatal system following a unilateral 6-hydroxydopamine striatal and medial forebrain lesion. [Poster Presentation], 8th Neuroscience Ireland Conference 2013, Cork, Ireland , 03-SEP-13 - 06-SEP-13. [Details] | |
| (2012) | 7th Neuroscience Ireland Conference, Gavin A, Wyatt S, Sullivan AM, O'Keeffe GW (2012) Expression of endogenous GDF5, GDNF, and their receptors in the rat nigrostriatal pathway following a unilateral 6-hydroxydopamine terminal lesion. [Poster Presentation], 7th Neuroscience Ireland Conference, Dublin, Ireland , 05-SEP-12 - 06-SEP-12. [Details] | |
| (2012) | UCC Doctoral Showcase [Finalist], Hegarty SV, O’Keeffe GW, Sullivan AM. (2012) Parkinson’s disease: Can we move in the right direction?. [Oral Presentation], UCC Doctoral Showcase [Finalist], Cork, Ireland , 07-JUN-12 - 07-JUN-12. [Details] | |
| (2012) | 7th Neuroscience Ireland Conference, Hegarty SV, Sullivan AM, O’Keeffe GW. (2012) GDF5 and BMP2 have differential effects on rat ventral mesencephalic neural stem cells, depending on their developmental stage. [Poster Presentation], 7th Neuroscience Ireland Conference, Dublin, Ireland , 05-SEP-12 - 06-SEP-12. [Details] | |
| (2011) | IBRO World Congress of Neuroscience 2011, Gavin A, Wyatt S, Sullivan AM, O'Keeffe GW. (2011) Analysis of the temporal expression and neurotrophic effects of GDNF in the developing rat nigrostriatal system. [Poster Presentation], IBRO World Congress of Neuroscience 2011, Florence, Italy , 14-JUL-11 - 18-JUL-11. [Details] | |
| (2011) | 6th Neuroscience Ireland 2011, Hegarty SV, Sullivan AM, O'Keeffe GW. (2011) The Development of Rat Ventral Mesencephalic Neural Stem Cells in vitro. [Poster Presentation], 6th Neuroscience Ireland 2011, Maynooth, Ireland , 01-SEP-11 - 02-SEP-11. [Details] | |
| (2010) | Neuroscience Ireland 2010, Crampton SJ, Sullivan AM, O'Keeffe GW. (2010) Stereological analysis of the brachypod mouse brain. [Poster Presentation], Neuroscience Ireland 2010, Dublin, Ireland , 02-SEP-10 - 03-SEP-10. [Details] | |
| (2010) | 5th Neuroscience Ireland, Gavin A, Wyatt S, Sullivan AM, O'Keeffe GW. (2010) Spatiotemporal analysis of GDF-5 expression in the developing rat nigrostriatal system. [Poster Presentation], 5th Neuroscience Ireland, Dublin, Ireland , 02-SEP-10 - 03-SEP-10. [Details] | |
| (2007) | Irish Network of Neural Stem Cell Investigators, Sullivan, A.M. (2007) rish Network of Neural Stem Cell Investigators. [Conference Organising Committee Member], Irish Network of Neural Stem Cell Investigators, Dublin , 01-JAN-07 - 01-JAN-07. [Details] | |
| (2006) | Irish Society for Gene and Cell Therapy meeting, Sullivan, A.M. (2006) Neuroprotective and restorative therapies for Parkinson's disease. [Oral Presentation], Irish Society for Gene and Cell Therapy meeting, Galway , 01-JAN-06 - 01-JAN-06. [Details] | |
| (2006) | Irish Network of Neural Stem Cell Investigators, Sullivan, A.M. (2006) Organising Committee Member. [Conference Organising Committee Member], Irish Network of Neural Stem Cell Investigators, Dublin , 01-JAN-06 - 01-JAN-06. [Details] | |
| (2005) | 16th International Conference on Parkinson's Disease, Harris, D.M., Fisher, A., Mandel, A., Bolton, A.E., Sullivan, A.M., Nolan, Y. (2005) 6-hydroxydopamine-induced degeneration of rat nigral dopaminergic neurons and microglial activation is reduced by treatment with a novel phospholipid-based drug formulation. [Poster Presentation], 16th International Conference on Parkinson's Disease, Berlin, Germany , 05-JUN-05 - 09-JUN-05. [Details] | |
| (2005) | 16th International Conference on Parkinson's Disease, Toulouse, A., Sullivan, A.M. (2005) Investigation of the neurotrophic effects of growth/differentiation factor 5 in an in vitro model of Parkinson' s disease. [Poster Presentation], 16th International Conference on Parkinson's Disease, Berlin, Germany , 05-JUN-05 - 09-JUN-05. [Details] | |
| (2005) | 16th International Conference on Parkinson's Disease, Kelly, T.A., Harrison, P.T., Scallan, M.F., Sullivan, A.M. (2005) Lentiviral-mediated delivery of growth/differentiation factor 5 attenuates parkinsonian symptoms in the rat. [Poster Presentation], 16th International Conference on Parkinson's Disease, Berlin, Germany , 05-JUN-05 - 09-JUN-05. [Details] | |
| (2005) | Irish Network of Neural Stem Cell Investigators, Sullivan, A.M. (2005) Irish Network of Neural Stem Cell Investigators. [Conference Organising Committee Member], Irish Network of Neural Stem Cell Investigators, Dublin , 01-JAN-05 - 01-JAN-05. [Details] | |
| (2005) | School of Biosciences, Sullivan, A.M. (2005) GDF5 and neural stem cells for the treatment of Parkinson's disease. [Oral Presentation], School of Biosciences, Cardiff University , 01-JAN-05 - 01-JAN-05. [Details] | |
| (2005) | Launch of Institute of Neuroscience, Sullivan, A.M. (2005) Neuroprotective therapies. [Invited Oral Presentation], Launch of Institute of Neuroscience, Trinity College Dublin , 01-JAN-05 - 01-JAN-05. [Details] | |
| (2005) | Royal Irish Academy of Medicine, Fitzgerald, P., Harris, D.M., Crotty, S., Fisher, A., Mandel, A., Bolton, A.E., Sullivan, A.M., Nolan, Y.M. (2005) 6-hydroxydopamine-induced degeneration of rat nigral dopaminergic neurons and microglial activation is reduced by treatment with a novel phospholipid-based drug formulation. [Poster Presentation], Royal Irish Academy of Medicine, Dublin, Ireland , 05-JUN-05 - 06-JUN-05. [Details] | |
| (2005) | 7th European Meeting in Glial Cell Function in Health and Disease, Barrett, R.J., McDermott, K.W., Sullivan, A.M. (2005) The effects of astroglial and neurotrophic interactions on the survival of dopaminergic neurons in vitro. [Poster Presentation], 7th European Meeting in Glial Cell Function in Health and Disease, Amsterdam, Holland , 20-MAY-05 - 23-MAY-05. [Details] | |
| (2005) | School of Biosciences Cardiff University, Sullivan, A.M. (2005) GDF5 and neural stem cells for the treatment of Parkinson's disease. [Oral Presentation], School of Biosciences Cardiff University, School of Biosciences Cardiff University , 01-JAN-05 - 01-JAN-05. [Details] | |
| (2005) | launch of Institute of Neuroscience Trinity College Dublin, Sullivan, A.M. (2005) Neuroprotective therapies for Parkinson's disease. [Oral Presentation], launch of Institute of Neuroscience Trinity College Dublin, Trinity College Dublin , 01-JAN-05 - 01-JAN-05. [Details] | |
| (2005) | Meeting of the Physiological Society, Flynn, R., O’Sullivan, D., Sullivan, A.M., Harrison, P. (2005) Use of pCEP4 Vector for Simple and Rapid Establishment of Stable Cell-Lines and Long-Term Gene Expression. [Poster Presentation], Meeting of the Physiological Society, Bristol, UK , 02-AUG-05 - 04-AUG-05. [Details] | |
| (2005) | Royal Irish Academy of Medicine, Harris, D.M., Fisher, A., Harkin, A.J., Bolton,A.E., Sullivan, A.M., Nolan, Y.M. (2005) Novel phospholipid-based drug formulation prevents degeneration of dopaminergic neurons from substantia nigra in a rat model of Parkinson’s disease. [Poster Presentation], Royal Irish Academy of Medicine, Dublin, Ireland , 05-JAN-05 - 06-JAN-05. [Details] | |
| (2005) | 13th Annual Medical Faculty Research Day. Cork, June 2005, Barrett, R.J., McDermott, K.W. & Sullivan, A.M. (2005) The effects of astroglial and dopaminergic neurotrophins on the survival of dopaminergic neurons in vitro. [Poster Presentation], 13th Annual Medical Faculty Research Day. Cork, June 2005, Cork , 01-MAY-05 - 01-MAY-05. [Details] | |
| (2004) | Irish Network of Stem Cell Investigators meeting, Sullivan, A.M. (2004) Neuronal stem cells for the treatment of Parkinson¿s disease. [Oral Presentation], Irish Network of Stem Cell Investigators meeting, Dublin , 01-JAN-04 - 01-JAN-04. [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland meeting, Sullivan, A.M. (2004) Effects of GDF5 on the induction and survival of dopaminergic neurones. [Oral Presentation], Anatomical Society of Great Britain and Ireland meeting, Cork , 01-JAN-04 - 01-JAN-04. [Details] | |
| (2004) | Irish Network of Neural Stem Cell Investigators, Sullivan, A.M. (2004) Irish Network of Neural Stem Cell Investigators. [Conference Organising Committee Member], Irish Network of Neural Stem Cell Investigators, Dublin , 01-JAN-04 - 01-JAN-04. [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland, Sullivan, A.M. (2004) Anatomical Society of Great Britain and Ireland. [Conference Organising Committee Member], Anatomical Society of Great Britain and Ireland, Cork , 01-JAN-04 - 01-JAN-04. [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting, Sullivan A.M. (2004) Effects of growth / differentiation factor 5 (GDF5) on the induction and survival of midbrain dopaminergic neurones. [Invited Oral Presentation], Anatomical Society of Great Britain and Ireland Summer Meeting, Cork, Ireland , 06-AUG-04 - 08-AUG-04. [Details] | |
| (2004) | 4th Forum of European Neuroscience, Barrett, R.J., McDermott, K.W., Sullivan, A.M. (2004) The roles of GDNF GDF-5 and astroglia on the survival of mesencephalic dopaminergic neurons in vitro. [Poster Presentation], 4th Forum of European Neuroscience, Lisbon, Portugal , 10-JUL-04 - 14-JUL-04. [Details] | |
| (2004) | 4th Forum of European Neuroscience, Clayton, K.B., Sullivan, A.M. (2004) Growth/differentiation factor-5 (GDF-5) expression in the developing and adult rat brain. [Poster Presentation], 4th Forum of European Neuroscience, Lisbon, Portugal , 10-JUL-04 - 14-JUL-04. [Details] | |
| (2004) | 4th Forum of European Neuroscience, O’Sullivan, D.B., Harrison, P.T., Sullivan, A.M. (2004) Establishment of neurotrophin-expressing dopaminergic cells for transplantation in Parkinson’s disease. [Poster Presentation], 4th Forum of European Neuroscience, Lisbon, Portugal , 10-JUL-04 - 14-JUL-04. [Details] | |
| (2004) | 4th Forum of European Neuroscience, Shanley, D.K., Sullivan, A.M. (2004) Cellular differentiation in neurosphere cultures of embryonic day 14 rat cortical and striatal tissue. [Poster Presentation], 4th Forum of European Neuroscience, Lisbon, Portugal , 10-JUL-04 - 14-JUL-04. [Details] | |
| (2004) | 4th Forum of European Neuroscience, Spitere, K., Sullivan, A.M. (2004) Cellular composition and gene expression in embryonic rat ventralmesencephalic neurosphere cultures. [Poster Presentation], 4th Forum of European Neuroscience, Lisbon, Portugal , 10-JUL-04 - 14-JUL-04. [Details] | |
| (2004) | 4th Forum of European Neuroscience, Toulouse, A., Sullivan, A.M. (2004) Investigation of the role of GDF-5 in the growth and differentiation of human neuroblastoma cells. [Poster Presentation], 4th Forum of European Neuroscience, Lisbon, Portugal , 10-JUL-04 - 14-JUL-04. [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting, Shanley, D.K., Sullivan, A.M. (2004) In vitro expansion and differentiation of neurospheres derived from embryonic day 14 rat cortical and striatal tissue. [Poster Presentation], Anatomical Society of Great Britain and Ireland Summer Meeting, Cork, Ireland , 06-AUG-04 - 08-AUG-04. [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting, Spitere, K., Sullivan, A.M. (2004) Characterisation of the cellular populations and dopaminergic gene cascade in rat ventral mesencephalic neural stem cell cultures. [Poster Presentation], Anatomical Society of Great Britain and Ireland Summer Meeting, Cork, Ireland , 06-AUG-04 - 06-AUG-04. [Details] | |
| (2004) | 34th Annual Meeting of the Society for Neuroscience, Fisher, A., Harris, D.M., Harkin, A.J., Bolton, A.E., Sullivan, A.M., Nolan Y.M. (2004) Novel phospholipid-based drug formulation retards the 6-hydroxydopamine-induced degeneration of rat nigral dopaminergic neurons. [Poster Presentation], 34th Annual Meeting of the Society for Neuroscience, San Diego USA , 23-OCT-04 - 27-OCT-04. [Details] | |
| (2004) | 34th Annual Meeting of the Society for Neuroscience, O’Keeffe, G.W., Toulouse, A., Sullivan, A.M. (2004) Dopaminergic induction from expanded rat ventral mesencephalic progenitor cells by GDF5 and BMP2 requires signalling through BMPR-Ib. [Poster Presentation], 34th Annual Meeting of the Society for Neuroscience, San Diego, USA , 23-OCT-04 - 27-OCT-04. [Details] | |
| (2004) | 34th Annual Meeting of the Society for Neuroscience, Toulouse, A., Sullivan, A.M. (2004) Roles of type 1 BMP receptors in the induction of midbrain dopaminergic neurones by GDF5. [Poster Presentation], 34th Annual Meeting of the Society for Neuroscience, San Diego USA , 23-OCT-04 - 27-OCT-04. [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting, Kelly, T.A., Harrison, P.T., Scallan, M.F., Sullivan, A.M. (2004) Viral vectors to deliver neurotrophin genes to a rat model of Parkinson's disease. [Poster Presentation], Anatomical Society of Great Britain and Ireland Summer Meeting, Cork, Ireland , 06-AUG-04 - 08-AUG-04. [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting, Harty, M., Sullivan, A.M., McDermott, K.W. (2004) Astroglial diversity in dopaminergic nuclei implications for selective neuronal degeneration and Parkinson’s disease. [Poster Presentation], Anatomical Society of Great Britain and Ireland Summer Meeting, Cork, Ireland , 06-AUG-04 - 08-AUG-04. [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting, O’Sullivan, D.B., Harrison, P.T., Sullivan, A.M. (2004) Rat ventral mesencephalic cultures transfected with a plasmid expressing growth/differentiation factor 5 exhibit improved dopaminergic neuronal survival. [Poster Presentation], Anatomical Society of Great Britain and Ireland Summer Meeting, Cork, Ireland , 06-AUG-04 - 08-AUG-04. [Details] | |
| (2004) | 15th Biennial Meeting of the International Society for Developmental Neuroscience,, Shanley, D.K., Sullivan, A.M. (2004) Expression and characterisation of the neuronal cell surface markers 2F7 and E-NCAM within the developing rat brain: An in vitro analysis of the development of neuronal restricted precursors. [Poster Presentation], 15th Biennial Meeting of the International Society for Developmental Neuroscience,, Edinburgh, UK , 04-AUG-04 - 07-AUG-04. [Details] | |
| (2004) | 15th Biennial Meeting of the International Society for Developmental Neuroscience, Spitere, K., Sullivan, A.M. (2004) A comparison of genetic cascades involved in induction of dopaminergic neuronal fate in the developing rodent ventral mesencephalon embryonic stem cells and neural stem cells. [Poster Presentation], 15th Biennial Meeting of the International Society for Developmental Neuroscience, Edinburgh, UK , 04-AUG-04 - 07-AUG-04. [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting, Barrett, R.J., McDermott, K.W., Sullivan, A.M. (2004) The effects of GDNF GDF5 and astroglia on the survival of rat mesencephalic dopaminergic neurons in vitro. [Poster Presentation], Anatomical Society of Great Britain and Ireland Summer Meeting, Cork, Ireland , 06-AUG-04 - 08-AUG-04. [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting, Clayton, K.B., Sullivan, A.M. (2004) Investigation of the spatio-temporal pattern of expression of the neurotrophin growth/differentiation factor 5 in the developing and adult rat brain. [Poster Presentation], Anatomical Society of Great Britain and Ireland Summer Meeting, Cork, Ireland , 06-AUG-04 - 08-AUG-04. [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting, Crotty, S., Sullivan, A.M., So, K.F., Chau, W.K.D., Sharma, A.K., Dockery, P. (2004) Cytoskeletal Reorganisation in Neurons: A Stereological Approach. [Poster Presentation], Anatomical Society of Great Britain and Ireland Summer Meeting, Cork, Ireland , 06-AUG-04 - 08-AUG-04. [Details] | |
| (2004) | Physiological Society meeting, Kelly, T.A., Harrison, P.T., Scallan, M.F., Sullivan, A.M. (2004) Viral vectors to deliver neurotrophin genes to a rat model of Parkinson’s disease. [Poster Presentation], Physiological Society meeting, Bristol, UK , 11-SEP-04 - 12-SEP-04. [Details] | |
| (2004) | Anatomical Society of Great Britain and Ireland Summer Meeting, Toulouse, A., Sullivan, A.M. (2004) Investigation of the effects of the neurotrophin GDF-5 on the growth and differentiation of SHSY-5Y cells. [Poster Presentation], Anatomical Society of Great Britain and Ireland Summer Meeting, Cork, Ireland , 06-AUG-04 - 08-AUG-04. [Details] | |
| (2003) | Brain Repair Group, Sullivan, A.M. (2003) GDF-5: a dopaminergic neurotrophin with potential for use in Parkinson's disease. [Oral Presentation], Brain Repair Group, Cardiff University , 01-JAN-03 - 01-JAN-03. [Details] | |
| (2003) | Dept. of Zoology Trinity College Dublin, Sullivan, A.M. (2003) Neuroprotective approaches to the treatment of Parkinson's disease. [Oral Presentation], Dept. of Zoology Trinity College Dublin, Dept. of Zoology Trinity College Dublin , 01-JAN-03 - 01-JAN-03. [Details] | |
| (2003) | 6th International Conference on Alzheimer`s and Parkinson`s Disease, Costello, D.J., O’Keeffe, G.W., Hurley, F.M., Hanke, M., Sullivan, A.M. (2003) A growth/differentiation factor 5-producing CHO cell line enhances the survival and function of dopaminergic grafts in a 6-OHDA rodent model of Parkinsonism. [Oral Presentation], 6th International Conference on Alzheimer`s and Parkinson`s Disease, Seville Spain , 08-MAY-03 - 12-MAY-03. [Details] | |
| (2003) | Anatomical Society of Great Britain and Ireland Winter Meeting,, O’Keeffe, G.W., Hanke, M., Sullivan, A.M. (2003) Growth/differentiation factor-5, a growth factor with potential for therapeutic approaches for Parkinson's disease. [Oral Presentation], Anatomical Society of Great Britain and Ireland Winter Meeting,, Egham, UK , 07-JAN-03 - 09-JAN-03. [Details] | |
| (2003) | 5th European Meeting on Glial Cell Function in Health and Disease, Wood, T.K., Sullivan, A.M., McDermott, K.W. (2003) In vitro analysis of astroglial-neuronal interactions in the ventral mesencephlon. [Poster Presentation], 5th European Meeting on Glial Cell Function in Health and Disease, Rome, Ital , 21-MAY-03 - 25-MAY-03. [Details] | |
| (2003) | 3rd Forum of European Neuroscience, Wood, T.K., Sullivan, A.M., McDermott, K.W. (2003) In vitro analysis of the effects of the neurotrophins GDF-5 GDNF and glial cells on dopaminergic neurone survival in the ventral mesencephalon. [Poster Presentation], 3rd Forum of European Neuroscience, Paris, France , 13-JUL-03 - 17-JUL-03. [Details] | |
| (2003) | Alzheimer’s and Parkinson’s diseases: New perspectives,, Costello, D.J., O’Keeffe,G.W., Hurley, F.M., Hanke, M., Sullivan, A.M. (2003) A growth/differentiation factor 5-producing CHO cell line enhances the survival and function of dopaminergic grafts in a 6-OHDA rodent model of Parkinsonism. [Poster Presentation], Alzheimer’s and Parkinson’s diseases: New perspectives,, Seville, Spain , 08-MAY-03 - 12-MAY-03. [Details] | |
| (2003) | Anatomical Society of Great Britain and Ireland, O’Keeffe, G.W., Hanke, M., Sullivan, A.M. (2003) Growth/differentiation factor-5, a growth factor with potential for therapeutic approaches to Parkinson’s disease. [Poster Presentation], Anatomical Society of Great Britain and Ireland, Egham,UK , 07-JAN-03 - 10-JAN-03. [Details] | |
| (2003) | Anatomical Society of Great Britain and Ireland Winter Meeting 2003, O’Keeffe, G.W., Hanke, M., Sullivan, A.M. (2003) Growth/differentiation factor-5, a growth factor with potential for therapeutic approaches for Parkinson's disease. [Best oral presentation]. [Oral Presentation], Anatomical Society of Great Britain and Ireland Winter Meeting 2003, Egham, UK , 07-JAN-03 - 10-JAN-03. [Details] | |
| (2003) | 6th International Conference on Alzheimer`s and Parkinson`s Disease, Costello, D.J., O'Keeffe, G.W., Hurley, F.M., Hanke, M., Sullivan, A.M. (2003) A growth/differentiation factor 5-producing CHO cell line enhances the survival and function of dopaminergic grafts in a 6-OHDA rodent model of Parkinsonism. [Poster Presentation], 6th International Conference on Alzheimer`s and Parkinson`s Disease, Seville, Spain , 08-MAY-03 - 12-MAY-03. [Details] | |
| (2003) | Annual Medical Research Day Cork University Hospital, June 2003, Harty, M., Barrett, R., Mc Dermott, K., Sullivan. A; (2003) Characterisation of the populations of dopaminergic neurons and astroglia in rat ventral mesencephalic and hypothalamic cultures. [Oral Presentation], Annual Medical Research Day Cork University Hospital, June 2003, Cork Hospital , 01-JUN-03 - 01-JUN-03. [Details] | |
| (2003) | Irish Society for Neurology meeting 2003, Costello, D.J., O'Keeffe, G.W., Hurley, F.M., Sullivan, A.M. (2003) A growth/differentiation factor 5 producing CHO cell line enhances the survival and function of dopaminergic grafts in a 6-OHDA rodent model of Parkinsonism. [Poster Presentation], Irish Society for Neurology meeting 2003, Cork, Ireland . [Details] | |
| (2003) | BioResearch Day, University College Cork, September 2003, Harty, M., Barrett, R., Mc Dermott, K., Sullivan. A. (2003) Characterisation of the populations of dopaminergic neurons and astroglia in rat ventral mesencephalic and hypothalamic cultures. [Poster Presentation], BioResearch Day, University College Cork, September 2003, University College Cork , 01-SEP-03 - 01-SEP-03. [Details] | |
| (2002) | National Parkinson's Disease Study Day, Sullivan, A.M. (2002) Stem cells and growth factors for Parkinson¿s disease. [Oral Presentation], National Parkinson's Disease Study Day, Dublin , 01-JAN-02 - 01-JAN-02. [Details] | |
| (2002) | Anatomical Society of Great Britain and Ireland Summer meeting 2002, O’Keeffe, G.W., Costello, D.J., Sullivan, A.M. (2002) Growth/differentiation factor-5: developmental regulator, potential treatment. [Poster Presentation], Anatomical Society of Great Britain and Ireland Summer meeting 2002, Dundee, Scotland , 23-JUL-12 - 26-JUL-12. [Details] | |
| (2002) | Irish Neuroscience Group meeting, Sullivan, A.M. (2002) Neuroprotective and restorative approaches to Parkinson¿s disease. [Oral Presentation], Irish Neuroscience Group meeting, Tullamore , 01-JAN-02 - 01-JAN-02. [Details] | |
| (2002) | 3rd Forum of European Neuroscience, O’Keeffe, G.W., Costello, D.J., Sullivan, A.M. (2002) Expression of the dopaminergic neurotrophin Growth differentiation factor-5 in the developing ventral mesencephalon and its effect on the differentiation of neural stem cells. [Poster Presentation], 3rd Forum of European Neuroscience, Paris, France , 13-JUL-02 - 17-JUL-02. [Details] | |
| (2002) | Anatomical Society of Great Britain and Ireland, O’Keeffe, G.W., Costello, D.J., Sullivan, A.M. (2002) Growth/differentiation factor-5: developmental regulator, potential treatment. [Poster Presentation], Anatomical Society of Great Britain and Ireland, Dundee, Scotland , 23-JUL-02 - 26-JUL-02. [Details] | |
| (2002) | Anatomical Society of Great Britain and Ireland Summer Meeting, O’Keeffe, G.W., Hanke, M., Sullivan, A.M. (2002) Growth/differentiation factor-5 (GDF-5) and dopaminergic neurones: developmental regulator potential treatment. [Oral Presentation], Anatomical Society of Great Britain and Ireland Summer Meeting, Dundee, Scotland , 23-JUL-02 - 25-JUL-02. [Details] | |
| (2002) | 3rd Forum of European Neuroscience, O’Keeffe, G.W., Costello, D.J., Sullivan, A.M. (2002) Expression of the dopaminergic neurotrophin Growth differentiation factor-5 in the developing ventral mesencephalon and its effect on the differentiation of neural stem cells. [Poster Presentation], 3rd Forum of European Neuroscience, Paris, France , 13-JUL-02 - 17-JUL-02. [Details] | |
| (2001) | Beaumont Hospital Neurology meeting, Sullivan, A.M. (2001) Cell transplantation for Parkinson¿s disease. [Oral Presentation], Beaumont Hospital Neurology meeting, Dublin , 01-JAN-01 - 01-JAN-01. [Details] | |
| (2001) | Anatomical Society of Great Britain and Ireland Summer Meeting 2001, O’Keeffe, G.W., Sullivan, A.M. (2001) Investigation of the expression of growth/differentiation factor-5 in the developing rat brain. [Best poster presentation]. [Poster Presentation], Anatomical Society of Great Britain and Ireland Summer Meeting 2001, Dublin, Ireland , 10-JUL-01 - 12-JUL-01. [Details] | |
| (2001) | Anatomical Society of Great Britain and Ireland Summer Meeting, Hurley, F.M., Costello, D.J., Sullivan, A.M. (2001) Neuroprotective effects of growth/differentiation factor-5 in a rat model of Parkinson's disease. [Poster Presentation], Anatomical Society of Great Britain and Ireland Summer Meeting, Dublin, Ireland , 10-JUL-01 - 12-JUL-01. [Details] | |
| (2001) | Anatomical Society of Great Britain and Ireland Summer Meeting, Costello, D.J., Hurley, F.M., Sullivan, A.M. (2001) Growth/differentiation factor-5 enhances graft survival and reverses motor asymmetry in a rat model of Parkinson's disease. [Poster Presentation], Anatomical Society of Great Britain and Ireland Summer Meeting, Dublin, Ireland, , 10-JUL-01 - 12-JUL-01. [Details] | |
| (2001) | Anatomical Society of Great Britain and Ireland Summer Meeting, 10-12th July 2001, O’Keeffe, G.W., Sullivan, A.M. (2001) Investigation of the expression of growth/differentiation factor-5 in the developing rat brain. [Poster Presentation], Anatomical Society of Great Britain and Ireland Summer Meeting, 10-12th July 2001, Dublin, Ireland , 10-JUL-01 - 12-JUL-01. [Details] | |
| (2001) | Anatomical Society of Great Britain and Ireland Summer Meeting, Wood, T.K., Sullivan, A.M., McDermott, K.W. (2001) Antimitotic treatment to achieve neurone enriched ventral mesencephalic cultures for studies of neurotrophins. [Poster Presentation], Anatomical Society of Great Britain and Ireland Summer Meeting, Dublin, Ireland , 10-JUL-01 - 12-JUL-01. [Details] | |
| (2000) | 2nd Forum of European Neuroscience, Wood, T.K., Sullivan, A.M., McDermott, K.W. (2000) Glia-depleted mesencephalic cultures for investigation of the action of the dopaminergic neurotrophins GDF-5 and GDNF. [Poster Presentation], 2nd Forum of European Neuroscience, Brighton, UK , 24-JUN-00 - 28-JUN-00. [Details] | |
| (2000) | Mater Hospital Neurology meeting, Sullivan, A.M. (2000) Neuroprotective approaches to Parkinson's disease. [Oral Presentation], Mater Hospital Neurology meeting, Dublin , 01-JAN-00 - 01-JAN-00. [Details] | |
| (1999) | Irish Neuroscience Group meeting, Sullivan, A.M. (1999) GDF5, a neurotrophic factor with potential for Parkinson's disease. [Oral Presentation], Irish Neuroscience Group meeting, Galway , 01-JAN-99 - 01-JAN-99. [Details] | |
| (1998) | Hammersmith Hospital Neurology meeting, Sullivan, A.M. (1998) Effects of GDF5 and GDNF in animal models of Parkinson's disease. [Oral Presentation], Hammersmith Hospital Neurology meeting, London , 01-JAN-98 - 01-JAN-98. [Details] | |
| (1998) | Charing Cross & Westminster Hospital Neuroscience meeting, Sullivan, A.M. (1998) GDF5, a neuroprotective protein with potential for Parkinson's disease treatment. [Oral Presentation], Charing Cross & Westminster Hospital Neuroscience meeting, London , 01-JAN-98 - 01-JAN-98. [Details] | |
| (1997) | XIIth International Symposium on Parkinson's Disease, Sullivan, A.M., Opacka-Juffry, J., Blunt, S.B.; (1997) Long-term protection of the rat nigrostriatal dopaminergic system by GDNF in vivo. [Poster Presentation], XIIth International Symposium on Parkinson's Disease, London, UK , 23-MAR-97 - 26-MAR-97. [Details] | |
| (1997) | 14th Meeting of Brain Research Association, Sullivan, A.M., Opacka-Juffry, J., Blunt, S.B. (1997) Long-term protection of the rat nigrostriatal dopaminergic system by GDNF in vivo. [Poster Presentation], 14th Meeting of Brain Research Association, Liverpool, UK , 07-APR-97 - 09-APR-97. [Details] | |
| (1997) | 27th Annual Meeting of the Society for Neuroscience, Sullivan, A.M., Opacka-Juffry J, Hotten G, Pohl J, Blunt S.B. (1997) Growth/differentiation factor 5 protects nigrostriatal dopaminergic neurones in a rat model of Parkinson’s disease. [Poster Presentation], 27th Annual Meeting of the Society for Neuroscience, New Orleans, USA , 25-OCT-97 - 30-OCT-97. [Details] | |
| (1996) | 13th Meeting of Brain Research Association, Ashworth, S., Opacka-Juffry, J., Sullivan, A.M., Banati, R.B., Blunt, S.B. (1996) Lack of functional nigrostriatal dopamine deficit following 6-hydroxydopamine injection into the striatum. [Poster Presentation], 13th Meeting of Brain Research Association, Newcastle, UK , 25-MAR-96 - 27-MAR-96. [Details] | |
| (1995) | 12th Meeting of Brain Research Association, Sullivan, A.M., Morton, A.J. (1995) Induction of Fos protein in organotypic cultures of rat cerebellum by endothelins. [Poster Presentation], 12th Meeting of Brain Research Association, Oxford, UK , 29-MAR-95 - 31-MAR-95. [Details] | |
| (1994) | 11th Meeting of Brain Research Association, Sullivan, A.M., Morton, A.J. (1994) Glutamate-induced expression of Fos protein by granule cells in organotypic cultures of rat cerebellum. [Poster Presentation], 11th Meeting of Brain Research Association, Southampton, UK , 10-APR-94 - 13-APR-94. [Details] | |
| (1994) | 11th Meeting of Brain Research Association, Sullivan, A.M., Morton, A.J. (1994) Is the development of Purkinje cell dendrites in organotypic culture of rat cerebellum dependent on granule cells?. [Poster Presentation], 11th Meeting of Brain Research Association, Southampton, UK , 10-APR-94 - 13-APR-94. [Details] |
Teaching Activities
Teaching Interests
- Professor Aideen Sullivan is Programme Director of the BSc in Medical and Health Science (CK707), a cross-College multidisciplinary degree which will begin student intake in 2018
- She was actively involved in the establishment and development of the BSc in Neuroscience in UCC, which started in 1998. She was Director and 4th Year co-ordinator of this degree from 1998 until 2016. She co-ordinates and teaches several modules on this degree, and practices research-led teaching in all modules.
- She is module co-ordinator and lecturer for the Neuroscience modules: AN2004, AN3003 and AN4009. She also lectures on modules AN3001, AN3011, AN3012, AN3013, AN4008, AN4013 and AN4014.
- In addition to the above modules on the BSc Neuroscience, Professor Sullivan co-ordinates and delivers lectures to other programmes, including AN1074 (Pharmacy), AN2007 (Dentistry), AN1004 (Dental Hygiene) and FM2101 (Medicine).
- She is a member of the programme committee for the MSc in Molecular Cell Biology with Innovation, and delivers lectures on module ML6002 for this course.
- Professor Sullivan supervises laboratory research projects each year for BSc Neuroscience (AN4011), and occasionally for intercalated BSc in Anatomy or Neuroscience (AN4011), BSc Genetics (GN4002), BSc Pharmacy (PF4004). She also supervises Masters-level laboratory research projects for the MSc Molecular Cell Biology with Innovation (ML6001) and MSc in Biotechnology (BT6002).
- Professor Sullivan acted as the Department of Anatomy and Neuroscience's representative on the College of Science, Engineering and Food Science Committee for Academic Programmes and Curriculum Developmeny from 2002 until 2016. She represented the Department on the Biological Sciences Committee from 2002 until its dissolution in 2009. She was Departmental representative on the CK402 (Biological and Chemical Sciences) Board of Studies until 2016.
- Professor Aideen Sullivan is invited external examiner for the MSc in Stem Cells and Regeneration in Bristol University, UK (2013-2018).
Current Postgraduate Students
- Grace Crotty MB BCh BAO. Doctoral Degree Structured (2013-2016). Biomarkers for Parkinson’s disease.
- Erin Dolan MPharm. Doctoral Degree Structured (2013-2016). Characterisation of cognitive deficits in the alpha-synuclein rat model of Parkinson’s disease.
Recent Postgraduates
| Graduation Year | Student Name | Institution | Degree Type | Thesis Title | |
|---|---|---|---|---|---|
| 2022 | Erin McCarthy | University College Cork | PHD | Defining the potential of ZNHIT1, an SNCA co-expressed gene in the substantia nigra, as a therapeutic target in Parkinson’s disease | |
| 2021 | Jayanth Anantha | University College Cork | PHD | Characterisation of the molecular mechanisms of dopaminergic axonal growth and their impairment in Parkinson's disease | |
| 2021 | Martina Mazzocchi | University College Cork | PHD | Defining the potential of class-IIa histone deacetylases as a therapeutic target for Parkinson’s disease | |
| 2020 | Amnah Alshangiti | University College Cork | PHD | From neurons to neuroblastoma: dietary flavonoids as regulators of life, death and differentiation | |
| 2019 | Rachel Furlong | University College Cork | PHD | Investigating the mechanisms by which PINK1 protects against Parkinson’s disease | |
| 2019 | Sarah O’Donovan | University College Cork | PHD | The microbiome-gut-brain axis in preclinical alpha-synuclein rat models of Parkinson’s disease | |
| 2017 | Sinead Campion | University College Cork | Investigation of microRNAs regulation of the bone morphogenetic protein-Smad signalling pathway’ | ||
| 2017 | Erin Dolan | University College Cork | PHD | Non-motor symptoms in the AAV-alpha-synuclein rat model of Parkinson’s disease: exercise as a therapeutic intervention | |
| 2015 | Eimear O’Leary | University College Cork | Interrogating the contribution of epigenetic regulation in BMP-Smad signal-induced neuronal differentiation | ||
| 2014 | Shane Hegarty | University College Cork | PhD | ‘Characterisation of the role of canonical BMP-Smad 1/5/8 signalling in the development of ventral midbrain dopaminergic neurons’ | |
| 2013 | Aisling Gavin | University College Cork | PhD | ‘Expression and function of the neurotrophic factors GDF5 and GDNF in the nigrostriatal system during development and in rat models of Parkinson’s disease’ | |
| 2012 | Grace Collins | University College Cork | PhD | ‘Generation of a ‘suicide gene’ system for cell replacement therapy’ | |
| 2012 | Martin Kelly | University College Cork | MSc | ‘Optimisation of GDF5 protein expression from an adeno-associated viral vector in SH-SY5Y cell cultures’ | |
| 2010 | Sean Crampton | University College Cork | MSc | ‘Stereological quantification of GDF5-treated dopamine neurons in vitro and of the brachypod (GDF5-null) mouse brain’ | |
| 2010 | Aoife Keohane | University College Cork | PhD | ‘Effects of pro-inflammatory cytokines on the fate of embryonic and adult hippocampal neural precursor cells’ | |
| 2008 | Caitriona Long | University College Cork | PhD | ‘The role of inflammation and p38 in 6-hydroxydopamine-induced dopaminergic neuronal death-implications for Parkinson’s disease’ | |
| 2007 | Robert Barrett | University College Cork | PhD | ‘The effects of astroglia on dopaminergic neuronal survival: implications for Parkinson’s disease’ | |
| 2006 | Kevin Clayton | University College Cork | PhD | ‘The expression and function of growth/differentiation factor 5 in the rat midbrain’ | |
| 2006 | Meghan Coakley | University College Cork | MSc | ‘Examination of the roles of DJ-1 and PINK-1 and their interaction with the survival signalling pathway controlled by Akt and PTEN in adult brain and in Parkinson’s disease’ | |
| 2006 | Suzanne Crotty | University College Cork | MSc | ‘Morphological correlates of cell death in a model of Parkinson’s disease’ | |
| 2006 | Emma McDonnell | University College Cork | MSc | ‘Sub-cloning and expression analysis of the Ki67 promoter’ | |
| 2006 | David O'Sullivan | University College Cork | PhD | ‘Establishment of growth/differentiation factor 5-expressing cells for transplantation in a model of Parkinson’s disease’ | |
| 2006 | Daniel Shanley | University College Cork | PhD | ‘Characterisation and manipulation of expanded neural progenitor cells derived from the embryonic rat brain’ | |
| 2006 | Katie Spitere | University College Cork | PhD | ‘Generation of an enriched population of dopaminergic neurones from neural stem cells’ | |
| 2004 | Jennifer Godsell | University College Cork | MSc | ‘Optimisation of neural stem cell culture techniques’ | |
| 2004 | Margo Harty | University College Cork | MSc | ‘Astrocyte diversity in dopaminergic nuclei: implications for selective neuronal degeneration and Parkinson’s disease’ | |
| 2004 | Gerard O'Keeffe | University College Cork | PhD | ‘The role of the dopaminergic neurotrophin growth/differentiation factor 5 in the developing rat ventral midbrain’ | |
| 2004 | Terri Wood | University College Cork | PhD | ‘Dopaminergic neurotrophins and astroglial-neuronal interactions in the rat ventral mesencephalon’ | |
| 2003 | Daniel Shanley | University College Cork | MSc | ‘Quantification of cellular phenotypes arising from embryonic day 14 rat cortical and striatal tissue grown in long-term neurosphere culture’ | |
| 2002 | Daniel Costello | University College Cork | MD | ‘Use of a cell line expressing the neurotrophin GDF5 to enhance the efficacy of transplanted dopaminergic neurons in a rat model of Parkinson’s disease’ | |
| 2001 | Fiona Hurley | University College Cork | MSc | ‘Neuroprotective and restorative effects of GDF5 in rat models of Parkinson’s disease’ |
Current Postgraduate Students
| Student | Degree Type | |
|---|---|---|
| Mc Carthy Erin | Doctoral Degree | |
| Bevans Rebekah | Doctoral Degree | |
| Morisho Jolie Zainabu | Doctoral Degree | |
| Wilson Fionnuala Elizabeth | Doctoral Degree | |
| Osayande Joan Omosefe | Doctoral Degree |
Research Information
Internal Collaborators
| Name | Institute | Country | |
|---|---|---|---|
| Dr Cora O'Neill | University College Cork | IRELAND | |
| Dr Sean O'Sullivan | Cork University Hospital | IRELAND | |
| Dr Andre Toulouse | University College Cork | IRELAND | |
| Dr Yvonne Nolan | University College Cork | IRELAND | |
| Dr Gerard O'Keeffe | University College Cork | IRELAND | |
| Dr Suzanne Timmons | St Finbarr's Hospital, Cork | IRELAND |
External Collaborators
| Name | Organisation / Institute | Country | |
|---|---|---|---|
| Dr Eilis Dowd | National University of Ireland, Galway | IRELAND | |
| Dr Frank Ploeger | Biopharm GmbH | GERMANY | |
| Dr Karen Keeshan | University of Glasgow | SCOTLAND | |
| Prof. Maeve Caldwell | Trinity College Dublin | IRELAND | |
| Prof. Michael Zigmond | University of Pittsburgh | U.S.A. | |
| Dr Michele Morari | University of Ferrara | ITALY | |
| Dr Sean Wyatt | Cardiff University | WALES |
Contact details
- Professor (Scale 2) /Head of Department PhD(Cantab), BSc, PG Cert T& L
- a.sullivan@ucc.ie
- Western Gateway Building
Western Road
Cork - +353 21 4205427
- www.ucc.ie/en/anatomy/