Research Profile

Olivia O'Leary

Biography

Dr. Olivia O'Leary is a Senior Lecturer in the Department of Anatomy and Neuroscience and Director of the BSc Neuroscience Programme in UCC. Olivia graduated with a BSc in Biotechnology, NUI, Galway, followed by an MSc in Neuropharmacology at the same institution.  She was a visiting scholar for over three years at the University of Pennsylvania, Philadelphia, USA, where she conducted her PhD research in behavioural neuropharmacology.  This was followed by postdoctoral research at the Neuroscience Centre at the University of Helsinki where her research was focused on the role of neuronal plasticity in pathophysiology and treatment of psychiatric disorders.  In 2008, Olivia was awarded a prestigious Career Development Award from the Health Research Board to conduct her research at the School of Pharmacy, University College Cork, where she was appointed as lecturer in 2011.  Olivia then joined the Department of Anatomy and Neuroscience as a lecturer in 2012, followed by promotion to Senior Lecturer.        

Olivia's main research interest is in the neurobiology and treatment of stress-related psychiatric disorders with a particular focus on depression.  Her research has been published in high-impact journals including PNAS and Science.  In addition, Olivia has been the recipient of several awards from international professional societies including  the 2015 most outstanding Junior Faculty Award from the International Behavioural and Neural Genetics Society (IBANGS), The Rafaelsen Young Investigator Award from the International College of Neuropsychopharmacology (2011) and the Fellowship Award from the European College of Neuropsychopharmacology (ECNP; 2010), as well the career development award from the Health Research Board Ireland (2008-2011).  Most recently, Olivia was honoured with the 2020 ECNP Citation Award.  In addition to her teaching and research activities, Olivia is an expert reviewer for >90 international journals and 19 international funding agencies. She is on the Editorial Board for 7 International Journals, acts as an external examiner for PhD thesis and was the external examiner for the BSc (Hons) Biology and Biopharmaceutical Science programme at Atlantic Technological University (2014-2020) and a Judge for the Life Science Industry Awards (2023, 2024). Olivia is a member of several committees focused on teaching, research and the student experience, at departmental, school, college and university levels. 



Research Interests


I lead a research group focused on determining the effects and consequences of psychological stress on the brain and identifying the biological mechanisms and factors that determine vulnerability or resilience to stress-induced depression, anxiety, and cognitive dysfunction. My research has increased understanding of  how antidepressant drugs exert their therapeutic  effects (e.g. Science PMID:18420937; PNAS PMID:15148402; Psychoneuroendocrinology PMID:18977602) and has identified novel biological mediators of stress resilience including FKBP51 (Mol Psych PMID: 36104438) and the GABAB1 receptor (PNAS PMID: 25288769). Much of my research focuses on the role of the hippocampus area of the brain and neurogenesis (the production of new neurons) as a cellular mediator of stress, anxiety, antidepressant action, and learning & memory. How the hippocampus has functions as diverse as memory and antidepressant action is not understood, but my research has shown that neurogenesis specifically in the ventral region but not the dorsal region of the hippocampus, plays a key role in responses to stress and antidepressants (e.g. Mol Psych PMID: 32709996). My research also discovered that the gut microbiome and neural signalling from the gut to the brain regulates hippocampal neurogenesis (Biol Psych PMID: 25700599; PMID: 29426666), findings that led to my 2020 Citation Award from the European College of Neuropsychopharmacology. My current SFI-funded project is focused on determining the mechanisms underlying the microbiota -gut-neurogenesis axis and the implications that this has for cognitive function and stress-related psychiatric disorders. My current research programme also investigates interactions between stress, the gut microbiota and female brain health (cognition, anxiety, depression) during hormonal transition periods of life (puberty, post-partum, menopause, e.g. PMID: 36532376) which may potentially explain the higher susceptibility of females to stress-related psychiatric disorders when compared with their male counterparts. 

Research Grants

 ProjectFunding
Body
Start DateEnd DateAward
Early Identification of Suicide and Self Harm Risk and Comorbid Mental and Physical Disorders: An INterdisciplinary TrAining, Research and InterventioN Programme (MHAINTAIN)Health Research Board01-APR-2201-APR-27€165,600.00
Unlocking the mechanisms underlying gut microbial regulation of adult hippocampal neurogenesis: Implications for cognitive and stress-related brain disordersScience Foundation Ireland01-DEC-2130-NOV-25€623,636.00
Investigating the impact of gut microbial metabolites and gut microbiota manipulation on the generation of new neurons in the hippocampus area of the brain01-JUL-2430-AUG-24€3,000.00
Investigating the effects of a magnesium-rich marine mineral blend (MMB) on stress induced changes in anxiety- and depression-like behaviour, hippocampal neurogenesis and proteomic profileIndustry Sponsor01-APR-2231-DEC-24€75,000.00
Sex matters, The role of maternal gut microbiota in shaping increased susceptibility of females to stress-related psychiatric disorders.Foreign Research Institute01-APR-2131-DEC-24€50,000.00
HEACOVID1901-SEP-2130-NOV-21€4,625.00
HEACOVID1901-SEP-2131-DEC-21€16,069.00
Investigation of the contribution of the gut microbiome in the behavioural and biological effects of the antidepressant, FluoxetineIrish Research Council01-SEP-1901-SEP-21€48,000.00
Inflammatory mechanisms underlying the negative effects of a cafeteria diet on brain and behaviour: exercise as a mitigating strategyIrish Research Council01-SEP-1901-SEP-22€72,000.00
Elucidation of the neural networks underlying sex differences in vulnerability to develop depression.Health Research Board01-JUN-1901-AUG-19€2,000.00
Sex Matters. Identification of Novel Therapeutic Targets to Mitigate the Increased Prevelance of Depression in Women Versus Men.Health Research Board01-DEC-1731-DEC-21€357,498.00
Validation of a novel therapeutic target for stress-related psychiatric disordersIndustry Sponsor01-JUL-1701-JUL-19€295,973.00
Gut Microbial Systems and Parkinson's Disease pathophysiology; Identification of novel microbial modifiable targets and biomarkers for a major neurodegenerative diseaseOther: Not Listed01-SEP-1501-SEP-19€118,000.00
Conference & Workshop GrantScience Foundation Ireland01-JUN-1801-JUL-18€17,300.00
ERC Application Support FundUCC Strategic Research Fund01-JAN-1501-JAN-16€2,500.00
Novel insights into the roles of the hippocampus and hippocampal neurogenesis in stress and antidepressant action”Other: Not Listed01-SEP-1401-SEP-18€136,792.00
Optogenetics - a platform for shedding light on brain dysfunctio n.Miscellaneous01-OCT-1330-SEP-14€10,000.00
Stress-Induced Alterations in Hippocampal Neuroplasticity and Behaviour: Effects of Antidepressants and Glycogen Synthase Kinase-3beta InhibitorsHealth Research Board01-OCT-0801-OCT-11€283,000.00

Contract Researchers

 Researcher NameProjectRoleFunding Body
Dr Andrew Octavian SasmitaAlzheimer’s diseasePostdoctoral Researcher
Lewis O'ConnorStress induced alterations in blood proteomeResearch Assistant
Dr Sarah NicolasMechanisms underpinning the interplay between chronic neuroinflammation and exercise on cognitive function during middle age.Postdoctoral Researcher
Dr Stephen ShovlinMechanisms underpinning the interplay between chronic neuroinflammation and exercise on cognitive function during middle age.Postdoctoral Researcher
Dr Thieza MeloInvestigating the effects of a magnesium-rich marine mineral blend (MMB) on stress induced changes in anxiety- and depression-like behaviour, hippocampal neurogenesis and proteomic profilePostdoctoral Researcher
Francisca Manriquez VillalobosSex matters! The role of maternal gut microbiota in shaping increased susceptibility of females to stress related psychiatric disordersResearch Assistant
Dr Nirit KaraNovel Antidepressant Target ValidationPostdoctoral ResearcherIndustry Sponsor
Dr Martin CodagnoneNovel Antidepressant Target validationPostdoctoral Researcher
Dr Thieza MeloMechanisms underpinning the interplay between chronic neuroinflammation and exercise on cognitive function during middle age.Research Assistant
Dr Erin HarrisSex Matters. Identification of Novel Therapeutic Targets to Mitigate the Increased Prevelance of Depression in Women Versus Men.Postdoctoral Researcher
Dr Michael LyonsGut Microbiome & hippocampal neurogenesisPostdoctoral Researcher

Publications

Book Chapters

 YearPublication
(2020)'Revisiting the Behavioral Genetics of Serotonin: Relevance to Anxiety and Depression'
*O'Leary OF, Codagnone MG, *Cryan JF (2020) 'Revisiting the Behavioral Genetics of Serotonin: Relevance to Anxiety and Depression' In: The Handbook of the Behavioral Neurobiology of Serotonin. USA: Academic Press. [Details]
(2020)'GABAB Receptors and Stress Resilience: A Tale of Two Isoforms'
O’Leary OF, Cryan JF (2020) 'GABAB Receptors and Stress Resilience: A Tale of Two Isoforms' In: Stress Resilience: Molecular and Behavioral Aspects. x: Elsevier Inc./Academic Press. [Details]
(2019)'Gene by environment interactions in animal models of depression and anxiety'
Felice D., Gururajan A, O’Leary O.F, Cryan J.F (2019) 'Gene by environment interactions in animal models of depression and anxiety' In: Andrei C. Miu,Judith Homberg and Klaus-Peter Lesch (eds). Genes, Brain and Emotions: Resilience and Psychopathology. x: Oxford University Press. [Details]
(2016)'Targeting the GABAB Receptor for the Treatment of Depression and Anxiety Disorders'
Daniela Felice, Olivia F. O’Leary, John F. Cryan (2016) 'Targeting the GABAB Receptor for the Treatment of Depression and Anxiety Disorders' In: GABA B Receptor. Swritzerland: Srpinger. [Details]
(2010)'Neurotrophic factors and antidepressant action: Recent advances'
O'Leary OF, Castren E; (2010) 'Neurotrophic factors and antidepressant action: Recent advances' In: Depression: From Psychopathology to Pharmacotherapy; Mod Trends Pharmacopsychiatry. Basel: Karger. [Details]
(2010)'The behavioural Genetics of serotonin: relevance to anxiety and depression'
O'Leary OF, Cryan JF ; (2010) 'The behavioural Genetics of serotonin: relevance to anxiety and depression' In: Handbook of the Behavioral Neurobiology of Serotonin. USA: Academic Press. [Details]
(2009)'The tail suspension test: A model for characterizing antidepressant activity in mice'
O'Leary OF, Cryan JF; (2009) 'The tail suspension test: A model for characterizing antidepressant activity in mice' In: Mood & Anxiety Related Phenotypes in Mice; Neuromethods. USA: Springer. [Details]

Peer Reviewed Journals

 YearPublication
(2024)'Plasma proteomic signature of chronic psychosocial stress in mice'
O'Connor LA;Melo TG;Golubeva AV;Donoso F;Scaife C;English JA;Nolan YM;O'Leary OF; (2024) 'Plasma proteomic signature of chronic psychosocial stress in mice'. Physiology & behavior, [DOI] [Details]
(2024)'Ageing, Cognitive Decline, and Effects of Physical Exercise: Complexities, and Considerations from Animal Models'
Caruso MG, Nicolas S, Lucassen PJ, Mul J, *O’Leary, OF, *Nolan, YM (2024) 'Ageing, Cognitive Decline, and Effects of Physical Exercise: Complexities, and Considerations from Animal Models'. Brain Plasticity (Amsterdam, Netherlands), 9 (1-2):43-73 [DOI] [Details]
(2024)'Examining patterns of patient adherence to Cognitive Behavioural Therapy in chronic physical illnesses and comorbid mental health disorders: a scoping review protocol'
Khan A, O’Leary OF, Corcoran P, Kelleher E, Ismail MF, Hursztyn P, Arensman (2024) 'Examining patterns of patient adherence to Cognitive Behavioural Therapy in chronic physical illnesses and comorbid mental health disorders: a scoping review protocol'. HRB Open Research,   [DOI] [Details]
(2023)'Microbiota from Alzheimer's patients induce deficits in cognition and hippocampal neurogenesis'
Grabrucker S;Marizzoni M;Silajdžic E;Lopizzo N;Mombelli E;Nicolas S;Dohm-Hansen S;Scassellati C;Moretti DV;Rosa M;Hoffmann K;Cryan JF;O'Leary OF;English JA;Lavelle A;O'Neill C;Thuret S;Cattaneo A;Nolan YM; (2023) 'Microbiota from Alzheimer's patients induce deficits in cognition and hippocampal neurogenesis'. Brain, 146 (12) [DOI] [Details]
(2023)'Outrunning a bad diet: Interactions between exercise and a Western-style diet for adolescent mental health, metabolism and microbes'
Nota MHC;Nicolas S;O'Leary OF;Nolan YM; (2023) 'Outrunning a bad diet: Interactions between exercise and a Western-style diet for adolescent mental health, metabolism and microbes'. Neuroscience and Biobehavioral Reviews, 149 [DOI] [Details]
(2022)'Stress during puberty exerts sex-specific effects on depressive-like behavior and monoamine neurotransmitters in adolescence and adulthood'
Harris, Erin P.; Villalobos-Manriquez, Francisca; Melo, Thieza G.; Clarke, Gerard; O'Leary, Olivia F. (2022) 'Stress during puberty exerts sex-specific effects on depressive-like behavior and monoamine neurotransmitters in adolescence and adulthood'. Neurobiology of Stress, [DOI] [Full Text] [Details]
(2022)'GABAB Receptors: Anxiety and Mood Disorders'
Felice D;Cryan JF;O'Leary OF; (2022) 'GABAB Receptors: Anxiety and Mood Disorders'. Current Topics In Behavioral Neurosciences, 52 [DOI] [Details]
(2022)'Inhibition of FKBP51 induces stress resilience and alters hippocampal neurogenesis'
Codagnone, MG;Kara, N;Ratsika, A;Levone, BR;van de Wouw, M;Tan, LA;Cunningham, JI;Sanchez, C;Cryan, JF;O'Leary, OF (2022) 'Inhibition of FKBP51 induces stress resilience and alters hippocampal neurogenesis'. Molecular Psychiatry, [DOI] [Details]
(2022)'Microbiota-Gut-Brain Axis Regulation of Adult Hippocampal Neurogenesis'
Guzzetta KE;Cryan JF;O'Leary OF; (2022) 'Microbiota-Gut-Brain Axis Regulation of Adult Hippocampal Neurogenesis'. Brain Plasticity (Amsterdam, Netherlands), 8 (1) [DOI] [Details]
(2022)'Juvenile stress exerts sex-independent effects on anxiety, antidepressant-like behaviours and dopaminergic innervation of the prelimbic cortex in adulthood and does not alter hippocampal neurogenesis'
Harris, Erin P.; McGovern, Andrew J.; Melo, Thieza G.; Barron, Aaron; Nolan, Yvonne M.; O’Leary, Olive F; (2022) 'Juvenile stress exerts sex-independent effects on anxiety, antidepressant-like behaviours and dopaminergic innervation of the prelimbic cortex in adulthood and does not alter hippocampal neurogenesis'. Behavioural Brain Research, 421 (421) [DOI] [Full Text] [Details]
(2021)'Specific sub-regions along the longitudinal axis of the hippocampus mediate antidepressant-like behavioral effects'
Levone, BR;Moloney, GM;Cryan, JF;O'Leary, OF (2021) 'Specific sub-regions along the longitudinal axis of the hippocampus mediate antidepressant-like behavioral effects'. Neurobiology of Stress, 14 [DOI] [Details]
(2021)'Specific sub-regions of the longitudinal axis of the hippocampus mediate behavioural responses to chronic psychosocial stress'
Levone, Brunno Rocha; Cryan, John F.; O'Leary, Olivia F. (2021) 'Specific sub-regions of the longitudinal axis of the hippocampus mediate behavioural responses to chronic psychosocial stress'. Neuropharmacology, [DOI] [Details]
(2021)'Prior maternal separation stress alters the dendritic complexity of new hippocampal neurons and neuroinflammation in response to an inflammatory stressor in juvenile female rats'
Nicolas, Sarah; McGovern, Andrew J.; Hueston, Cara M.; O'Mahony, Siobhain M.; Cryan, John F.; O'Leary, Olivia F.; Nolan, Yvonne M. (2021) 'Prior maternal separation stress alters the dendritic complexity of new hippocampal neurons and neuroinflammation in response to an inflammatory stressor in juvenile female rats'. Brain Behav Immun, [DOI] [Full Text] [Details]
(2021)'Adult-born neurons from the dorsal, intermediate, and ventral regions of the longitudinal axis of the hippocampus exhibit differential sensitivity to glucocorticoids'
Levone B.R.;Codagnone M.G.;Moloney G.M.;Nolan Y.M.;Cryan J.F.;O’ Leary O.F. (2021) 'Adult-born neurons from the dorsal, intermediate, and ventral regions of the longitudinal axis of the hippocampus exhibit differential sensitivity to glucocorticoids'. Molecular Psychiatry, [DOI] [Details]
(2021)'Microbiota from young mice counteracts selective age-associated behavioral deficits'
Boehme M;Guzzetta KE;Bastiaanssen TFS;van de Wouw M;Moloney GM;Gual-Grau A;Spichak S;Olavarría-Ramírez L;Fitzgerald P;Morillas E;Ritz NL;Jaggar M;Cowan CSM;Crispie F;Donoso F;Halitzki E;Neto MC;Sichetti M;Golubeva AV;Fitzgerald RS;Claesson MJ;Cotter PD;O'Leary OF;Dinan TG;Cryan JF; (2021) 'Microbiota from young mice counteracts selective age-associated behavioral deficits'. Nature Aging, 1 (8) [DOI] [Details]
(2020)'Depression's Unholy Trinity: Dysregulated Stress, Immunity, and the Microbiome'
Cruz-Pereira JS;Rea K;Nolan YM;O'Leary OF;Dinan TG;Cryan JF; (2020) 'Depression's Unholy Trinity: Dysregulated Stress, Immunity, and the Microbiome'. Annual Review Of Psychology, 71 [DOI] [Details]
(2019)'Nigral overexpression of a-synuclein in a rat Parkinson’s disease model indicates alterations in the enteric nervous system and the gut microbiome'
O’Donovan S.;Crowley E.;Brown J.;O’Sullivan O.;O’Leary O.;Timmons S.;Nolan Y.;Clarke D.;Hyland N.;Joyce S.;Sullivan A.;O'Neill C. (2019) 'Nigral overexpression of a-synuclein in a rat Parkinson’s disease model indicates alterations in the enteric nervous system and the gut microbiome'. Neurogastroenterology and Motility, [DOI] [Details]
(2019)'Chronic intrahippocampal interleukin-1ß overexpression in adolescence impairs hippocampal neurogenesis but not neurogenesis-associated cognition'
Pawley, Lauren C.; Hueston, Cara M.; O'Leary, James D.; Kozareva, Danka A.; Cryan, John F.; O'Leary, Olivia F.; Nolan, Yvonne M. (2019) 'Chronic intrahippocampal interleukin-1ß overexpression in adolescence impairs hippocampal neurogenesis but not neurogenesis-associated cognition'. Brain Behav Immun,   [DOI] [Full Text] [Details]
(2019)'Without a bug's life: Germ-free rodents to interrogate microbiota-gut-neuroimmune interactions'
Spichak S.;Guzzetta K.;O'Leary O.;Clarke G.;Dinan T.;Cryan J. (2019) 'Without a bug's life: Germ-free rodents to interrogate microbiota-gut-neuroimmune interactions'. Drug Discovery Today, [DOI] [Details]
(2019)'Enduring Effects of Muscarinic Receptor Activation on Adult 2 Hippocampal Neurogenesis, MicroRNA expression and Behaviour 3 4'
Ramos Costa AP, Levone BR; Gururajan A, Moloney G, Hoeller A, Lino-de-Oliveira C, Dinan TG, O’Leary OF, Monteiro de Lima TC, Cryan JF* (2019) 'Enduring Effects of Muscarinic Receptor Activation on Adult 2 Hippocampal Neurogenesis, MicroRNA expression and Behaviour 3 4'. Behavioural Brain Research, 362 :188-198 [Details]
(2019)'Differential Effects of Adolescent and Adult‐initiated Exercise on Cognition and Hippocampal Neurogenesis'
James D. O'Leary Alan E. Hoban Ashley Murphy Olivia F. O'Leary John F. Cryan Yvonne M. Nolan (2019) 'Differential Effects of Adolescent and Adult‐initiated Exercise on Cognition and Hippocampal Neurogenesis'. Hippocampus, 4 :352-365 [DOI] [Details]
(2019)'Programming Bugs: Microbiota and the Developmental Origins of Brain Health and Disease'
Codagnone, Martin G.; Spichak, Simon; O’Mahony, Siobhain M.; O’Leary, Olivia F.; Clarke, Gerard; Stanton, Catherine; Dinan, Timothy G.; Cryan, John F. (2019) 'Programming Bugs: Microbiota and the Developmental Origins of Brain Health and Disease'. Biological Psychiatry, 85 (2):150-163   [DOI] [Full Text] [Details]
(2019)'Differential effects of adolescent and adult-initiated voluntary exercise on context and cued fear conditioning'
O'Leary JD;Hoban AE;Cryan JF;O'Leary OF;Nolan YM; (2019) 'Differential effects of adolescent and adult-initiated voluntary exercise on context and cued fear conditioning'. Neuropharmacology, 45 (Pt A):49-58 [DOI] [Details]
(2018)'Differential Effects of Adolescent and Adult-initiated Exercise on Cognition and Hippocampal Neurogenesis'
James D. O’Leary, Alan E. Hoban, Ashley Murphy, Olivia F. O'Leary, John F. Cryan and Yvonne M. Nolan 2* (2018) 'Differential Effects of Adolescent and Adult-initiated Exercise on Cognition and Hippocampal Neurogenesis'. Hippocampus, [Details]
(2018)'A low-cost touchscreen operant chamber using a Raspberry Pi™'
O'Leary JD, O'Leary OF, Cryan JF, Nolan YM. (2018) 'A low-cost touchscreen operant chamber using a Raspberry Pi™'. Behavioural Research Methods, 50 (6):2523-2530 [DOI] [Details]
(2018)'Chronic Interleukin-1β in the Dorsal Hippocampus Impairs Behavioural Pattern Separation'
Hueston CM, O'Leary JD, Hoban AE, Kozareva DA, Pawley LC, O'Leary OF, Cryan JF, Nolan YM. (2018) 'Chronic Interleukin-1β in the Dorsal Hippocampus Impairs Behavioural Pattern Separation'. Brain Behav Immun, 74 :252-264 [Details]
(2018)'The Vagus Nerve Modulates BDNF expression and Neurogenesis in the Hippocampus'
O’Leary OF*, Ogbonnaya ES, Felice D, Levone BR, Conroy L, Fitzgerald P, Bravo JA, Forsythe P, Bienenstock J, Dinan TG Cryan JF (2018) 'The Vagus Nerve Modulates BDNF expression and Neurogenesis in the Hippocampus'. European Neuropsychopharmacology, 28 (2):307-331 [Details]
(2018)'Deletion of Tlx and social isolation impairs exercise-induced neurogenesis in the adolescent hippocampus'
Kozareva DA, O'Leary OF, Cryan JF, Nolan YM. (2018) 'Deletion of Tlx and social isolation impairs exercise-induced neurogenesis in the adolescent hippocampus'. Hippocampus, 28 (1):3-11 [Details]
(2018)'Elucidation of the Neural Circuits Activated by a GABAB Receptor Positive Modulator: Relevance to Anxiety'
Pizzo R*, O’Leary OF* and Cryan JF (2018) 'Elucidation of the Neural Circuits Activated by a GABAB Receptor Positive Modulator: Relevance to Anxiety'. Neuropharmacology, 136 (Pt A):129-145 [Details]
(2018)'Regulation of behaviour by the nuclear receptor Tlx'
James D. O’Leary, Olivia F. O'Leary, John F. Cryan and Yvonne M. Nolan (2018) 'Regulation of behaviour by the nuclear receptor Tlx'. Genes Brain And Behavior, 17 (3) [DOI] [Details]
(2017)'Microbial regulation of hippocampal miRNA expression: Implications for transcription of kynurenine pathway enzymes'
Moloney GM, O'Leary OF, Salvo-Romero E, Desbonnet L, Shanahan F, Dinan TG, Clarke G, Cryan JF. (2017) 'Microbial regulation of hippocampal miRNA expression: Implications for transcription of kynurenine pathway enzymes'. Behavioural Brain Research, 334 :50-54 [Details]
(2017)'The hippocampus and dorsal raphe nucleus are key brain areas associated with the antidepressant effects of lithium augmentation of desipramine'
Cussotto S, Cryan JF, O’Leary OF (2017) 'The hippocampus and dorsal raphe nucleus are key brain areas associated with the antidepressant effects of lithium augmentation of desipramine'. Neuroscience Letters, 648 :14-20 [DOI] [Details]
(2016)'Inhibiting Neuroinflammation: The Role and Therapeutic Potential of GABA in Neuro-Immune Interactions'
Crowley T, Cryan JF, Downer EJ, O’Leary OF (2016) 'Inhibiting Neuroinflammation: The Role and Therapeutic Potential of GABA in Neuro-Immune Interactions'. Brain Behav Immun, 54 :260-277 [DOI] [Details]
(2016)'The nuclear receptor Tlx regulates motor, cognitive and anxiety-related behaviours during adolescence and adulthood'
O’LearyJD, Kozareva DA, Hueston CM, O'Leary OF, Cryan JF and NolanYM (2016) 'The nuclear receptor Tlx regulates motor, cognitive and anxiety-related behaviours during adolescence and adulthood'. Behav. Brain Res, 306 :36-47 [DOI] [Details]
(2016)'Differential Roles of GABAB1 Subunit Isoforms on Locomotor Responses to Acute and Repeated Administration of Cocaine'
Jacobson LH, Sweeney F, Kaupmann K, O’Leary OF, Gassmann M, Bettler B, Cryan JF (2016) 'Differential Roles of GABAB1 Subunit Isoforms on Locomotor Responses to Acute and Repeated Administration of Cocaine'. Behavioral Brain Research, 298 (Pt B):12-16 [DOI] [Details]
(2015)'Modulation of TLR3/TLR4 inflammatory signaling by the GABAB receptor agonist baclofen in glia and immune cells: relevance to therapeutic effects in multiple sclerosis'
Crowley T, Fitzpatrick J, Kuijper T, Cryan JF, O’Toole O, O'Leary OF, Downer EJ (2015) 'Modulation of TLR3/TLR4 inflammatory signaling by the GABAB receptor agonist baclofen in glia and immune cells: relevance to therapeutic effects in multiple sclerosis'. Frontiers in Cellular Neuroscience, 9 [Details]
(2015)'When ageing meets the blues: are current antidepressants effective in depressed aged patients'
Felice D, O’Leary OF, Cryan JF, Dinan TG, Gardier A, Sanchez C, David DJ (2015) 'When ageing meets the blues: are current antidepressants effective in depressed aged patients'. Neuroscience & Biobehavioral Reviews, 55 :478-497 [Details]
(2015)'Adult hippocampal neurogenesis is regulated by the microbiome'
Ogbonnaya ES, Clarke G, Shanahan F, Dinan TG, Cryan JF, O'Leary OF (2015) 'Adult hippocampal neurogenesis is regulated by the microbiome'. Biological Psychiatry, 78 (4):e7-9 [Details]
(2014)'Role of adult hippocampal neurogenesis in stress resilience'
Levone BR, Cryan JF, O'Leary OF (2014) 'Role of adult hippocampal neurogenesis in stress resilience'. Neurobiology of Stress, 1 :147-155 [DOI] [Details]
(2014)'Glycogen Synthase Kinase-3 as a Therapeutic Target for Cognitive Dysfunction in Neuropsychiatric Disorders'
O'Leary OF, Nolan YM (2014) 'Glycogen Synthase Kinase-3 as a Therapeutic Target for Cognitive Dysfunction in Neuropsychiatric Disorders'. Cns Drugs, [DOI] [Details]
(2014)'A Ventral View on Antidepressant Action: Roles for Adult Hippocampal Neurogenesis along the Dorso-ventral Axis'
O'Leary OF, Cryan JF (2014) 'A Ventral View on Antidepressant Action: Roles for Adult Hippocampal Neurogenesis along the Dorso-ventral Axis'. Trends In Pharmacological Sciences, 35 :675-687 [DOI] [Details]
(2014)'GABAB(1) receptor subunit isoforms differentially regulate stress resilience'
O'Leary OF, Felice D, Galimberti S, Savignac HM, Bravo JA, Crowley T, El Yacoubi M, Vaugeois JM, Gassmann M, Bettler B, Dinan TG, Cryan JF. (2014) 'GABAB(1) receptor subunit isoforms differentially regulate stress resilience'. Proceedings of The National Academy of Science Usa, 111 (42):15232-15237 [Details]
(2014)'Faster, Better, Stronger: Towards New Antidepressant Therapeutic Strategies'
O'leary O.F, Dinan T.G, Cryan J.F. (2014) 'Faster, Better, Stronger: Towards New Antidepressant Therapeutic Strategies'. European Journal of Pharmacology, 123 :55-76 [DOI] [Details]
(2014)'A review of ketamine in affective disorders: Current evidence of clinical efficacy, limitations of use and pre-clinical evidence on proposed mechanisms of action'
Naughton M, Clarke G, O'Leary OF, Cryan JF, Dinan TG (2014) 'A review of ketamine in affective disorders: Current evidence of clinical efficacy, limitations of use and pre-clinical evidence on proposed mechanisms of action'. Journal of Affective Disorders, 156 :24-35 [Details]
(2014)'Activation but not Blockade of GABAB Receptors During Early-life Alters Anxiety in Adulthood in BALB/c mice'
Sweeney F., O'Leary O.F., Cryan J.F. (2014) 'Activation but not Blockade of GABAB Receptors During Early-life Alters Anxiety in Adulthood in BALB/c mice'. Neuropharmacology, 81 :303-310 [Details]
(2013)'Drugs, Genes and the Blues: Pharmacogenetics of the Antidepressant Response from Mouse to Man'
O’Leary O.F., O’Brien F.E., O’Connor R.M., Cryan J.F. (2013) 'Drugs, Genes and the Blues: Pharmacogenetics of the Antidepressant Response from Mouse to Man'. Pharmacology Biochemistry and Behavior, (123):55-76 [Details]
(2013)'Towards translational rodent models of depression'
O'Leary OF, Cryan JF (2013) 'Towards translational rodent models of depression'. Cell Tissue Research, 354 (1):141-145 [Details]
(2013)'Hippocampal group III mGlu receptor mRNA levels are not altered in specific mouse models of stress, depression and antidepressant action'
O'Connor RM, Pusceddu M, O'Leary OF, Savignac HM, Bravo JF, El Yacoubi M, Vaugeois JM, Dinan TG, Cryan JF. (2013) 'Hippocampal group III mGlu receptor mRNA levels are not altered in specific mouse models of stress, depression and antidepressant action'. Pharmacology Biochemistry and Behavior, 103 (3):561-567 [DOI] [Details]
(2013)'GABAB receptor ligands do not modify conditioned fear responses in BALB/c mice'
Sweeney F.F., O'Leary O.F., Cryan J.F. (2013) 'GABAB receptor ligands do not modify conditioned fear responses in BALB/c mice'. Behavioural Brain Research, 256 :151-156 [DOI] [Details]
(2013)'Lithium Augmentation of the effects of Desipramine in a Mouse Model of Treatment-Resistant Depression: A Role for Hippocampal Cell Proliferation'
O'Leary OF, Zandy S, Dinan TG, Cryan JF (2013) 'Lithium Augmentation of the effects of Desipramine in a Mouse Model of Treatment-Resistant Depression: A Role for Hippocampal Cell Proliferation'. Neuroscience, 228 :36-46 [DOI] [Details]
(2012)'Blockade of the GABA(B) receptor increases neurogenesis in the ventral but not dorsal adult hippocampus: Relevance to antidepressant action'
Felice D, O'Leary OF, Pizzo RC, Cryan JF. (2012) 'Blockade of the GABA(B) receptor increases neurogenesis in the ventral but not dorsal adult hippocampus: Relevance to antidepressant action'. Neuropharmacology, 63 (8):1380-1388 [DOI] [Details]
(2012)'Lithium-induced effects on adult hippocampal neurogenesis are topographically segregated along the dorso-ventral axis of stressed mice'
O'Leary OF, O'Connor RM, Cryan JF; (2012) 'Lithium-induced effects on adult hippocampal neurogenesis are topographically segregated along the dorso-ventral axis of stressed mice'. Neuropharmacology, 62 (1):247-255 [DOI] [Details]
(2012)'Early-life stress induces visceral hypersensitivity in mice'
Moloney RD, O'Leary OF, Felice D, Bettler B, Dinan TG, Cryan JF. (2012) 'Early-life stress induces visceral hypersensitivity in mice'. Neuroscience Letters, 512 (2):99-102 [Details]
(2011)'Increased sensitivity to the effects of chronic social defeat stress in an innately anxious mouse strain'
Savignac HM, Finger BC, Pizzo RC, O'Leary OF, Dinan TG, Cryan JF; (2011) 'Increased sensitivity to the effects of chronic social defeat stress in an innately anxious mouse strain'. Neuroscience, 192 :524-536 [DOI] [Details]
(2010)'Neuroscience. A glutamate pathway to faster-acting antidepressants?'
Cryan JF, O'Leary OF.; (2010) 'Neuroscience. A glutamate pathway to faster-acting antidepressants?'. Science, 329 (5994):913-914 [Details]
(2009)'Chronic fluoxetine treatment increases expression of synaptic proteins in the hippocampus of the ovariectomized rat: role of BDNF signalling'
O'Leary OF, Wu X, Castren E; (2009) 'Chronic fluoxetine treatment increases expression of synaptic proteins in the hippocampus of the ovariectomized rat: role of BDNF signalling'. Psychoneuroendocrinology, 34 (3):367-381 [DOI] [Details]
(2008)'The antidepressant fluoxetine restores plasticity in the adult visual cortex'
Maya Vetencourt JF, Sale A, Viegi A, Baroncelli L, De Pasquale R, O'Leary OF, Castr�n E, Maffei L; (2008) 'The antidepressant fluoxetine restores plasticity in the adult visual cortex'. Science, 320 (5874):385-388 [DOI] [Details]
(2007)'Chronic antidepressant treatment selectively increases expression of plasticity-related proteins in the hippocampus and medial prefrontal cortex of the rat'
Sairanen M, O'Leary OF, Knuuttila JE, Castr�n E; (2007) 'Chronic antidepressant treatment selectively increases expression of plasticity-related proteins in the hippocampus and medial prefrontal cortex of the rat'. Neuroscience, 144 (1):368-374 [DOI] [Details]
(2007)'The role of noradrenergic tone in the dorsal raphe nucleus of the mouse in the acute behavioral effects of antidepressant drugs'
O'Leary OF, Bechtholt AJ, Crowley JJ, Valentino RJ, Lucki I; (2007) 'The role of noradrenergic tone in the dorsal raphe nucleus of the mouse in the acute behavioral effects of antidepressant drugs'. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 17 (3):215-226 [DOI] [Details]
(2007)'Depletion of serotonin and catecholamines block the acute behavioral response to different classes of antidepressant drugs in the mouse tail suspension test'
O'Leary OF, Bechtholt AJ, Crowley JJ, Hill TE, Page ME, Lucki I; (2007) 'Depletion of serotonin and catecholamines block the acute behavioral response to different classes of antidepressant drugs in the mouse tail suspension test'. Psychopharmacology, 192 (3):357-371 [DOI] [Details]
(2004)'Automated tests for measuring the effects of antidepressants in mice'
Crowley JJ, Jones MD, O'Leary OF, Lucki I; (2004) 'Automated tests for measuring the effects of antidepressants in mice'. Pharmacology Biochemistry and Behavior, 78 (2):269-274 [DOI] [Details]
(2004)'Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors'
Cryan JF, O'Leary OF, Jin SH, Friedland JC, Ouyang M, Hirsch BR, Page ME, Dalvi A, Thomas SA, Lucki I; (2004) 'Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors'. Proceedings of The National Academy of Sciences of The United States of America, 101 (21):8186-8191 [DOI] [Details]
(2004)'Distinguishing roles for norepinephrine and serotonin in the behavioral effects of antidepressant drugs'
Lucki I, O'Leary OF; (2004) 'Distinguishing roles for norepinephrine and serotonin in the behavioral effects of antidepressant drugs'. The Journal of Clinical Psychiatry, 65 Suppl 4 :11-24 [Details]

Conference Publications

 YearPublication
(2024)37th European College of Neuropsychopharmacology (ECNP) congress, 21-24 September 2024, Milan, Italy
Williams Z.A.P., Sasmita AO, Nave KA, O’Leary OF, Cryan JF, Nicolas S, Nolan YM (2024) Biological sex influences exercise-induced changes in memory, mood, and neuropathology in Alzheimer’s disease: a preclinical study 37th European College of Neuropsychopharmacology (ECNP) congress, 21-24 September 2024, Milan, Italy [Details]
(2024)XIst International Federation of Associations of Anatomists Congress, September 5-8, 2024 South Korea
Alturkustani S, Durfee A, O’Mahony SM, O’Leary OF, O’Mahony C, Lone M, Factor A (2024) Exploring Virtual Anatomy Learning: An Irish Students’ Perception XIst International Federation of Associations of Anatomists Congress, September 5-8, 2024 South Korea [Details]
(2024)37th European College of Neuropsychopharmacology (ECNP) congress, Milan, Italy
Caruso MG, Nicolas S, O’Leary OF, Nolan YM (2024) Exercise paradigms: contrasting effects of treadmill and voluntary wheel running on hippocampus-associated functions in rats 37th European College of Neuropsychopharmacology (ECNP) congress, Milan, Italy [Details]
(2024)SPHERE Conference, RCSI Dublin
Khan A, Arensman E, O’Leary OF, Corcoran P, Ismail MF, Kelleher E (2024) Examining patterns of patient adherence to Cognitive Behavioural Therapy in chronic physical illnesses and comorbid mental health disorders: a scoping review protocol SPHERE Conference, RCSI Dublin [Details]
(2024)5th Eurogenesis Meeting, Bordeaux, France
Nicolas S, Caruso MG, O’Leary OF, Nolan YM (2024) Chronic low grade hippocampal inflammation blunts an exercise-induced increase in hippocampal neurogenesis in rats 5th Eurogenesis Meeting, Bordeaux, France [Details]
(2024)5th Eurogenesis Meeing, Bordeaux, France
Caruso MG, Nicolas S, Dohm-Hansen S, Lucassen PJ, O’Leary OF, Nolan YM (2024) Rasal1: A potential exercise mimetic to increase adult hippocampal neurogenesis in middle age 5th Eurogenesis Meeing, Bordeaux, France [Details]
(2024)5th Eurogenesis Meeting, Bordeaux, France
Dohm-Hansen S, Caruso MG, Nicolas S, Melo T, Foley T, Scaife C, Lucassen PJ, Lavelle A, O'Leary OF, English JA, Nolan YM (2024) Rasal1 as a systemic regulator of exercise-induced changes in hippocampal neurogenesis 5th Eurogenesis Meeting, Bordeaux, France [Details]
(2023)European College of Neuropsychopharmacology (ECNP) Workshop for Young Scientists in Europe, Nice, France
Nota M.H.C., Nicolas S, Harris E.P., Foley T, *O’Leary OF, *Nolan YM (2023) Peripheral alterations underlying the interactions between a cafeteria diet and exercise on brain and behaviour European College of Neuropsychopharmacology (ECNP) Workshop for Young Scientists in Europe, Nice, France [Details]
(2023)2023 COMH Futures Research conference, UCC
Mulay KP, Donoso F, Caruso MG, Nicolas, Nota MHC, Foley, D-H. Allard S, Fitzgerald P, Prosilis A, Cryan JF, Nolan YM, *O’Leary OF (2023) Gut microbial depletion impairs spatial memory in a sex-dependent manner 2023 COMH Futures Research conference, UCC [Details]
(2023)Frontiers in Microbiome-Gut-Brain Science A Public Webinar from the Board on Life Sciences of the National Academy of Sciences USA
O'Leary OF (2023) Unlocking mechanisms underlying gut microbial regulation of adult hippocampal neurogenesis: Implications for cognitive and stress-related brain disorders Frontiers in Microbiome-Gut-Brain Science A Public Webinar from the Board on Life Sciences of the National Academy of Sciences USA [Details]
(2023)36th European College of Neuropsychopharmacology (ECNP) congress, Barcelona, Spain
Mulay KP, Donoso F, Caruso MG, Nicolas S, Nota MHC, Foley T, D-H Allard, Fitzgerald P, Prosilis Cryan JF, Nolan YM, *O’Leary OF. (2023) Gut microbial depletion impairs spatial memory in a sex-dependent manner 36th European College of Neuropsychopharmacology (ECNP) congress, Barcelona, Spain [Details]
(2023)2023 COMH Teaching and learning showcase, UCC
Durfee AA, Alturkustani S, O’Leary OF, O’Mahony SM, Lone M, O’Mahony C, Factor A (2023) Future Learning: Enhancing Students' Anatomy Understanding Using Virtual Reality Technology 2023 COMH Teaching and learning showcase, UCC [Details]
(2023)36th European College of Neuropsychopharmacology (ECNP) congress, Barcelona, Spain
Mulay KP, Donoso F, Caruso MG, Nicolas S, Nota MHC, Foley T, D-H Allard, Fitzgerald P, Prosilis Cryan JF, Nolan YM, *O’Leary OF. (2023) Gut microbial depletion impairs spatial memory in a sex-dependent manner 36th European College of Neuropsychopharmacology (ECNP) congress, Barcelona, Spain [Details]
(2022)The Irish Mass Spectrometry Society (IMSS)
Dohm-Hansen S, Lavelle A, Nicolas S, Caruso MG, Melo T, Foley T, Scaife C, Lucassen PJ, O’Leary OF, English J, Nolan YM (2022) Neuroproteomic profiling of the opposing effects of middle age and exercise on the rat dentate gyrus The Irish Mass Spectrometry Society (IMSS) [Details]
(2022)COMH Learning and Teaching Showcase, UCC, Ireland
Garcia P, O’Keeffe GW, *O’Leary OF (2022) Investigating ‘Air Anatomy’ as a pedagogical approach for learning Human Anatomy COMH Learning and Teaching Showcase, UCC, Ireland [Details]
(2022)COMH Inaugural conference From Molecules to People, UCC, Ireland
Villalobos-Manriquez F, Csatlosova K, Cryan JF, *O’Leary OF (2022) Effects of prebiotics on post-partum stress resilience: Implications for post-partum depression and anxiety disorders COMH Inaugural conference From Molecules to People, UCC, Ireland [Details]
(2022)APC Microbiome Institute annual symposium
O'Leary OF (2022) Unlocking mechanisms underlying gut microbial regulation of adult hippocampal neurogenesis:​ Implications for cognitive and stress-related brain disorders APC Microbiome Institute annual symposium [Details]
(2021)34th European College of Neuropsychopharmacology (ECNP) congress, Lisbon, Portugal
O'Leary OF (2021) Stress during puberty exerts sexually dimorphic effects on brain and antidepressant-like behaviour 34th European College of Neuropsychopharmacology (ECNP) congress, Lisbon, Portugal [Details]
(2021)34th European College of Neuropsychopharmacology (ECNP) congress, Lisbon, Portugal
Nota MHC, Kavanagh MA, Harris EP, Nicolas S, Foley T, *Nolan YM, *O’Leary OF (2021) Exercise mitigates the negative effects of a cafeteria diet on antidepressant-like behaviour in adult male rats 34th European College of Neuropsychopharmacology (ECNP) congress, Lisbon, Portugal [Details]
(2021)Neuroscience Ireland Conference (Virtual)
Nota M, *O’Leary OF, *Nolan YM (2021) Exercise mitigates the negative effects of a cafeteria diet on antidepressant-like behaviour in adult male rats Neuroscience Ireland Conference (Virtual) [Details]
(2020)Federation of European Neuroscience Societies Conference (Virtual)
Harris EP, *O’Leary OF (2020) Stress during puberty exerts sexually dimorphic effects on antidepressant-like behaviour in adolescence and adulthood Federation of European Neuroscience Societies Conference (Virtual) [Details]
(2020)European College of Neuropsychopharmacology (ECNP) congress (Virtual)
O'Leary OF (2020) The Vagus Nerve Modulates BDNF Expression and Neurogenesis in the Hippocampus European College of Neuropsychopharmacology (ECNP) congress (Virtual) [Details]
(2020)Neuroscience Ireland Young investigator Symposium (Virtual)
Harris EP, Villalobos FJ, Clarke G, *O’Leary OF (2020) Sex-specific effects of stress during puberty on antidepressant-like behaviour and monoamine neurotransmitters in adolescence and adulthood Neuroscience Ireland Young investigator Symposium (Virtual) [Details]
(2020)New Horizons Conference
Boehme M, Guzzetta KE, Bastiaanssen TFS, van de Wouw M, Gual-Grau A, Molony GM, Spichak S, Olavarria-Ramirez L, Fitzgerald, Morillas E, Ritz N, Jaggar M, Cowan CSM, Crispie F, Donoso F, Halitzki E, Neto MC, Sicchetti M, Golubeva AV, Fitzgerald RS, Claesson MJ, Cotter PD, O’Leary OF, Dinan TG, Cryan JF. (2020) Microbiota from Young Mice Counteracts the ​Effects of Aging on Hippocampal-Dependent Behavior and Neuroimmunity New Horizons Conference [Details]
(2020)American College of Neuropsychopharmacology Meeting (Virtual)
Harris EP, Villalobos-Manriquez F, Clarke G, *O’Leary OF (2020) Stress during Puberty Exerts Sexually Dimorphic Effects on Antidepressant-Like Behaviour and Monoamine Neurotransmitters in Adolescence and Adulthood American College of Neuropsychopharmacology Meeting (Virtual) [Details]
(2020)APC Microbiome Ireland Symposium, Cork
O'Leary OF (2020) Gut feelings, sex, stress, antidepressants & hippocampal neurogenesis APC Microbiome Ireland Symposium, Cork [Details]
(2020)Neuroscience Ireland, (Virtual)
Caruso MG, Harris EP, *O’Leary OF (2020) Effects of pubertal stress on hippocampal neurogenesis: role of biological sex Neuroscience Ireland, (Virtual) [Details]
(2019)European Behavioural Pharmacology Society Biennial Meeting, Braga, Portugal
O'Leary OF (2019) Emerging strategies for the treatment of stress-related psychiatric disorders European Behavioural Pharmacology Society Biennial Meeting, Braga, Portugal [Details]
(2019)BNA2019 Festival of Neuroscience, Dublin, Ireland
O’Donovan SM, Crowley E, O’Leary OF, Timmons S, Nolan YM, O’Sullivan O, Clarke DJ, Hyland NP, Joyce SA, Sullivan AM, O’Neill C (2019) The brain ↔ gut axis in Parkinson’s disease: enteric nervous system pathology and gut microbiome alterations in the AAV-synuclein rat model BNA2019 Festival of Neuroscience, Dublin, Ireland [Details]
(2019)New Horizons Conference, UCC, Cork
Daswani H, Harris E, *O’Leary OF (2019) Effects of prior juvenile stress on stressor-specific patterns of neural activation in adulthood: Role of Biological sex New Horizons Conference, UCC, Cork [Details]
(2019)Australasian Neuroscience Society 2019 conference, Adelaide, Australia
O’Leary OF (2019) FKBP51: An emerging therapeutic target for stress-related psychiatric disorders Australasian Neuroscience Society 2019 conference, Adelaide, Australia [Details]
(2019)New Horizons Conference, UCC, Cork
Daswani H, Harris E, *O’Leary OF (2019) Effects of prior juvenile stress on stressor-specific patterns of neural activation in adulthood: Role of Biological sex New Horizons Conference, UCC, Cork [Details]
(2019)New Horizons Conference
Guzzetta KE, Boehme M, Gual-Grau A, Bastiaanssen TFS, Spichak S, Morillas E, Jaggar M, Pereira J, van de Wouw M, Moloney GM, Ritz N, Dinan TG, O’Leary OF, Cryan JF (2019) The impact of age-associated microbiota on neuroimmunity, physiology, and behavior in germ-free mice New Horizons Conference [Details]
(2019)AWARE Conference - The Future of Depression & Bipolar disorder
O'Leary OF (2019) Emerging roles of the gut-brain axis and psychobiotics in depression AWARE Conference - The Future of Depression & Bipolar disorder [Details]
(2019)The Organization for the Study of Sex Differences (OSSD) 2019 Meeting Washington DC, USA
Harris EP, *O’Leary OF (2019) Behavioural Effects of Juvenile Stress in Adult Male and Female Rats The Organization for the Study of Sex Differences (OSSD) 2019 Meeting Washington DC, USA [Details]
(2019)BNA2019 Festival of Neuroscience, Dublin, Ireland
Pawley LC, McGovern A, O’Leary JD, Heuston CM, Kozareva DA, Cryan JF, *O’Leary OF, *Nolan YM (2019) Differential effects of chronic neuroinflammation on adult and adolescent hippocampal neurogenesis BNA2019 Festival of Neuroscience, Dublin, Ireland [Details]
(2019)Society for Free Radical Research – Europe SFRR-E Meeting
O’Leary OF (2019) Microbiota Gut-brain axis regulation of hippocampal neurogenesis and behaviour Society for Free Radical Research – Europe SFRR-E Meeting [Details]
(2019)Australasian Neuroscience Society 2019 conference, Adelaide, Australia
O’Leary OF (2019) FKBP51: An emerging therapeutic target for stress-related psychiatric disorders Australasian Neuroscience Society 2019 conference, Adelaide, Australia [Details]
(2019)New Horizons Conference, UCC, Ireland
Harris EP, *O’Leary OF (2019) Stress during puberty exerts sexually dimorphic effects on antidepressant-like behaviour New Horizons Conference, UCC, Ireland [Details]
(2019)26th Annual PsychoNeuroImmunolgy Research Society (PNIRS) and GEBIN Scientific Meeting, Berlin, Germany
Hueston CM, O’Leary JD, Kozareva DA, O’Leime CS, Hoban AE, Pawley LC, O’Leary OF, Cryan JF, Nolan YM (2019) Differential effects of chronic inflammation and exercise on hippocampal neurogenesis-associated behaviour through the lifespan 26th Annual PsychoNeuroImmunolgy Research Society (PNIRS) and GEBIN Scientific Meeting, Berlin, Germany [Details]
(2019)BNA2019 Festival of Neuroscience, Dublin, Ireland
Codagnone MG, Harrington J, Cunningham JI, Sanchez C, Cryan JF, *O’Leary OF (2019) FKBP5 inhibition increases hippocampal neurogenesis and neuronal outgrowth BNA2019 Festival of Neuroscience, Dublin, Ireland [Details]
(2019)European Behavioural Pharmacology Society Biennial Meeting, Braga, Portugal
O'Leary OF (2019) Emerging strategies for the treatment of stress-related psychiatric disorders European Behavioural Pharmacology Society Biennial Meeting, Braga, Portugal [Details]
(2019)The Organization for the Study of Sex Differences (OSSD) 2019 Meeting, Washington DC, USA
Harris EP, Codagnone MG, Kavanagh LN, Nolan YM, *O’Leary OF (2019) Sex Differences in Sensitivity of Hippocampal Neurogenesis to the Stress Hormone Corticosterone The Organization for the Study of Sex Differences (OSSD) 2019 Meeting, Washington DC, USA [Details]
(2019)Mind mood microbes 17-18 Jan, Amsterdam
Boehme M, Guzzetta K, van de Wouw M, Scott KA, Ida M, Olavarria-Ramirez, Moloney G, Minuto C, Golubeva AV, Morillas E, Cowan C, Ritz N, Bastiaanssen TFS, Clarke G, O’Leary OF, Schellekens H, Dinan TG, Cryan JF (2019) Microbiome, Neuroimmunity and Aging: Finding the Fountain of (Brain) Youth in our Gut Microbes? Mind mood microbes 17-18 Jan, Amsterdam [Details]
(2018)New Horizons Research Conference
Harris EP, Codagnone MG, *O'Leary OF (2018) Sex differences in the actions of corticosterone on hippocampal neural progenitor cells New Horizons Research Conference [Details]
(2018)Lake Como Neuroscience School, 9-13 April, Italy
Codagnone MG, O’Leary OF, Sanchez C, Cunningham J, Cryan JF, *O’Leary OF (2018) FKBP5 pharmacological inhibition as a novel strategy for the treatment of stress-related disorders: in vivo and in vitro approaches Lake Como Neuroscience School, 9-13 April, Italy [Details]
(2018)New Horizons Research Conference
O'Leary OF (2018) The Stressed Brain: From Neurobiology to Behaviour to Treatment Strategies New Horizons Research Conference [Details]
(2018)Young Neuroscience Ireland Symposium 2018, 25th October, University College Dublin, Ireland
O’Donovan SM, Dolan E, O’Leary OF, Timmons S, O’Toole PW, Clarke DJ, Hyland NP, Joyce SA, Sullivan AM, O’Neill C (2018) The Brain ↔ Gut Axis in Parkinson’s disease (PD): Alterations in Enteric Nervous System Pathology and Gut Microbiome in the rAAV-α-synuclein Rat Model of PD Young Neuroscience Ireland Symposium 2018, 25th October, University College Dublin, Ireland [Details]
(2018)New Horizons Research Conference
Codagnone MG, Cunningham JI, Sanchez C, Cryan JF, *O'Leary, OF (2018) FKBP5 pharmacological inhibition as a novel strategy for the treatment of stress-related disorders: in vivo and in vitro approaches New Horizons Research Conference [Details]
(2018)Young Neuroscience Ireland Symposium 2018, 25th October, University College Dublin, Ireland
Codagnone MG, Cunningham JI, Sanchez C, Cryan JF, *O’Leary OF (2018) FKBP5 pharmacological inhibition as a novel strategy for the treatment of stress-related disorders: in vivo and in vitro approaches Young Neuroscience Ireland Symposium 2018, 25th October, University College Dublin, Ireland [Details]
(2018)9th Meeting of International Society for Serotonin Research (ISSR), July 15- 19
Levone BR, Cryan JF, *O’Leary OF (2018) The anxiolytic and antidepressant effects of fluoxetine are mediated by specific regions along the longitudinal axis of the hippocampus 9th Meeting of International Society for Serotonin Research (ISSR), July 15- 19 [Details]
(2018)9th Meeting of International Society for Serotonin Research (ISSR), July 15- 19
Levone BR, Cryan JF, *O’Leary OF (2018) The anxiolytic and antidepressant effects of fluoxetine are mediated by specific regions along the longitudinal axis of the hippocampus 9th Meeting of International Society for Serotonin Research (ISSR), July 15- 19 [Details]
(2018)Young Neuroscience Ireland Symposium 2018
Harris E, Codagnone M, *O’Leary OF (2018) Intrinsic sex differences in hippocampal neurogenesis and its regulation by the stress hormone corticosterone Young Neuroscience Ireland Symposium 2018 [Details]
(2018)New Horizons Research Conference, University College Cork, Ireland
Pawley LC, O'Leary JD, Hueston CM, Cryan JF, *O'Leary OF, *Nolan YM (2018) The impact of chronic neuroinflammation on adult and adolescent hippocampal neurogenesis and on the stressed brain New Horizons Research Conference, University College Cork, Ireland [Details]
(2017)Society for Neuroscience (SFN) Conference, November 11-15 Washington DC, USA
O'Leary JD, Hoban AE, Brouwers C, Sullivan AM, O'Leary OF, Cryan JF, Nolan YM (2017) Differential effects of exercise during adolescence and adulthood on cognition and plasticity Society for Neuroscience (SFN) Conference, November 11-15 Washington DC, USA Washington DC, USA, [Details]
(2017)Lake Como Neuroscience School, 9-13 April, Italy
Codagnone MG, O’Leary OF, Sanchez C, Cunningham J, Cryan JF, *O’Leary OF (2017) FKBP5 pharmacological inhibition as a novel strategy for the treatment of stress-related disorders: in vivo and in vitro approaches Lake Como Neuroscience School, 9-13 April, Italy [Details]
(2017)New Horizons Conference
Novelli V, Levone BR, Cryan JF, *O’Leary OF (2017) The primary cilium in the CNS: an organelle of stress-related psychiatric disorders and antidepressant action? New Horizons Conference [Details]
(2017)New Horizons Conference, University College Cork
Kozareva DA, O’Leary OF, Cryan JF, Nolan YM (2017) Deletion of Tlx and social isolation impairs exercise-induced neurogenesis in the adolescent hippocampus New Horizons Conference, University College Cork [Details]
(2017)The 7th International Human Microbiome Congress (IHMC), June 26-28th, Killarney, County Kerry, Ireland
O’Donovan SM, Crowley EK, Browne J, O’Sullivan O, O’Leary OF, Timmons S, Nolan Y, O’Toole PW, Clarke DJ, Hyland NP, Joyce SA, Sullivan AM, O’Neill C (2017) Gut microbiome alterations and enteric nervous system pathology in the alpha-synuclein rat model of Parkinson's disease The 7th International Human Microbiome Congress (IHMC), June 26-28th, Killarney, County Kerry, Ireland [Details]
(2017)New Horizons Conference, UCC, Ireland
Levone BR, Cryan JF, *O’Leary OF (2017) Role of specific subregions along the longitudinal axis of the hippocampus in the behavioural responses to chronic stress New Horizons Conference, UCC, Ireland [Details]
(2017)New Horizons Conference
Novelli V, Levone BR, Cryan JF, *O’Leary OF (2017) The primary cilium in the CNS: an organelle of stress-related psychiatric disorders and antidepressant action? New Horizons Conference [Details]
(2014)Careers in Neuroscience Symposium Galway
Crowley T, Cryan JF, Downer EJ, O'Leary OF (2014) Investigation of the GABAB receptor as a modulator of central and peripheral inflammation Careers in Neuroscience Symposium Galway [Details]
(2013)Royal Academy of Medicine in Ireland (RAMI) Annual Meeting, University College Cork, June 2013
Ogbonnaya S, Clarke G, Shanahan FS, Cryan JF, O’Leary OF (2013) Establishment of the gut microbiome during early life influences the survival of newly-born cells in the adult hippocampus Royal Academy of Medicine in Ireland (RAMI) Annual Meeting, University College Cork, June 2013 [Details]
(2017)EBPS (European Behavioural Pharmacology Society) Biennial Meeting
Levone BR., Cryan JF., O’Leary OF. (2017) The anxiolytic and antidepressant effects of fluoxetine are mediated by specific regions of the longitudinal axis of the hippocampus EBPS (European Behavioural Pharmacology Society) Biennial Meeting Heraklion, Crete, Greece, , 31-AUG-17 - 03-SEP-17 [Details]
(2017)European Brain and Behaviour Society (EBBS)
O'Leary JD, Hoban AE, O'Leary OF, Cryan JF, Nolan YM (2017) DIFFERENTIAL EFFECTS OF EXERCISE DURING ADOLESCENCE AND ADULTHOOD ON COGNITION AND PLASTICITY European Brain and Behaviour Society (EBBS) [Details]
(2017)Neuroscience Ireland
Gerard M. Moloney1, Olivia O’ Leary1, Eloisa Salvo-Romero2, Lieve Desbonnet1, Fergus Shanahan3, Timothy G Dinan, Gerard Clarke4, John F Cryan1. (2017) Microbial regulation of hippocampal mirna expression: implications for transcription of kynurenine pathway enzymes Neuroscience Ireland NUI Galway, , 28-AUG-17 - 29-AUG-17 [Details]
(2017)Neuroscience Ireland
Danka A. Kozareva, Olivia F. O'Leary, John F. Cryan, Yvonne M. Nolan. (2017) Deletion of tlx and social isolation impairs exercise-induced neurogenesis in the adolescent hippocampus Neuroscience Ireland NUI Galway, , 28-AUG-17 - 29-AUG-17 [Details]
(2017)Neuroscience Ireland
SM O’Donovan, EK Crowley, J Browne, O O’Sullivan, OF O’Leary, S Timmons, YM Nolan, PW O’Toole, DJ Clarke, NP Hyland, SA Joyce, AM Sullivan, C O’Neill (2017) Investigation of the brain ↔ gut axis in the raav2/6-alpha-synuclein pd model: alterations in enteric nervous system pathology and the gut microbiome Neuroscience Ireland NUI Galway, , 28-AUG-17 - 29-AUG-17 [Details]
(2017)Neuroscience Ireland
Levone BR, Cryan JF, O'Leary OF (2017) The antidepressant effect of fluoxetine is mediated by specific sub-regions of the longitudinal axis of the hippocampus Neuroscience Ireland NUI Galway, , 28-AUG-17 - 29-AUG-17 [Details]
(2017)AD/PDTM 2017, the 13th​ International Conference on Alzheimer's and Parkinson's Diseases and Related Neurological Disorders
O’Donovan SM, Crowley E, Browne J, O’Sullivan O, O’Leary OF, Timmons S, Nolan YM, O’Toole PW, Clarke DJ, Hyland NP, Joyce SA, Sullivan AM, O’Neill C (2017) The brain ↔gut axis in Parkinson’s disease: defining gut pathology and the impact of exercise in the rAAV-­α-­synuclein rat model of PD AD/PDTM 2017, the 13th​ International Conference on Alzheimer's and Parkinson's Diseases and Related Neurological Disorders , 29-MAR-17 - 02-APR-17 [Details]
(2017)ECNP workshop for Junior Scientists in Europe
Levone BR, Nolan YM, Cryan JF, O'Leary OF (2017) Region-specific effects of corticosterone on neural progenitors along the dorso-ventral axis of the hippocampus ECNP workshop for Junior Scientists in Europe , 09-MAR-17 - 12-MAR-17 [Details]
(2016)New Horizons in Medical Research, December 8th 2016, University College Cork
Brunno R. Levone, John F. Cryan, Olivia F. O’Leary (2016) Regulation of anxiety behaviour by the ventral but not intermediate or dorsal areas of the hippocampus New Horizons in Medical Research, December 8th 2016, University College Cork [Details]
(2016)New Horizons in Medical Research, December 8th 2016, University College Cork
James D. O'Leary, Cynthia Brouwers, Niek Brosens, Olivia F. O'Leary, John F. Cryan, Aideen Sullivan and Yvonne M. Nolan (2016) Impact of voluntary exercise during adolescence on cognitive performance in a touchscreen operant chamber during adulthood New Horizons in Medical Research, December 8th 2016, University College Cork [Details]
(2016)New Horizons in Medical Research, December 8th 2016, University College Cork
SM O’Donovan, E Dolan, OF O’Leary, S Timmons, PW O’Toole, DJ Clarke, NP Hyland, SA Joyce, AM Sullivan, C O’Neill (2016) The brain ↔ gut axis in Parkinson’s disease (PD): Central nervous system administration of rAAV-α-synuclein altered gut pathophysiology and increased gut inflammation in the rAAV-α-synuclein rat model of PD New Horizons in Medical Research, December 8th 2016, University College Cork [Details]
(2016)Society for Neuroscience
James D. O'Leary, Cynthia Brouwers, Niek Brosens, Olivia F. O'Leary, John F. Cryan, Aideen M. Sullivan and Yvonne M. Nolan (2016) Impact of voluntary exercise during adolescence on cognitive performance in a touchscreen operant chamber during adulthood Society for Neuroscience [Details]
(2016)2016 Biochemical Society Meeting: Inflammatory diseases - mechanisms and clinical perspectives, 3—4 November 2016, Maynooth University, Ireland
SM O’Donovan, E Dolan, OF O’Leary, S Timmons, PW O’Toole, DJ Clarke, NP Hyland, SA Joyce, AM Sullivan, C O’Neill (2016) The brain ↔ gut axis in Parkinson’s disease (PD): Central nervous system administration of rAAV-α-synuclein altered gut pathophysiology and increased gut inflammation in the rAAV-α-synuclein rat model of PD 2016 Biochemical Society Meeting: Inflammatory diseases - mechanisms and clinical perspectives, 3—4 November 2016, Maynooth University, Ireland [Details]
(2016)APC Microbiome Institute Symposium
SM O’Donovan, E Dolan, OF O’Leary, S Timmons, PW O’Toole, DJ Clarke, NP Hyland, SA Joyce, AM Sullivan, C O’Neill (2016) The brain ↔ gut axis in Parkinson’s disease: defining gut pathophysiology in the rAAV-α-synuclein rat model of PD APC Microbiome Institute Symposium [Details]
(2016)Eurogenesis
Brunno R. Levone1, Yvonne M. Nolan, John F. Cryan, Olivia F. O’Leary (2016) Neural progenitor cells (NPCs) from the ventral hippocampus are more sensitive to long-term exposure to corticosterone than NPCs from the dorsal or intermediate hippocampus Eurogenesis Bordeaux, France, , 11-JUL-16 - 13-JUL-16 [Details]
(2016)Eurogenesis
James D. O'Leary, Danka A. Kozareva, Cara M. Hueston, Olivia F. O'Leary, John F. Cryan and Yvonne M. Nolan (2016) The nuclear receptor TLX regulates motor, cognitive and anxiety-related behaviours during adolescence and adulthood Eurogenesis Bordeaux, France, , 11-JUL-16 - 13-JUL-16 [Details]
(2016)Young Neuroscientists Symposium
Brunno R. Levone, John F. Cryan, Olivia F. O’Leary (2016) The hippocampus is functionally segregated along its longitudinal axis: A role for the ventral but not dorsal hippocampus in anxiety behaviour Young Neuroscientists Symposium [Details]
(2016)Young Neuroscientists Symposium
Conroy L, Levone BR, O’Leary OF (2016) ANTIDEPRESSANT-INDUCED REGULATION OF NEUROGENESISIS ALONG THE LONGITUDINAL AXIS OF THE HIPPOCAMPUS Young Neuroscientists Symposium [Details]
(2015)ICVS Neuroconferences workshop, Braga
Brunno Rocha Levone, Ciaran O’Leime, Yvonne M. Nolan, John F. Cryan, Olivia F. O’Leary (2015) THE EFFECTS OF CORTICOSTERONE ON NEUROPROGENITOR CELLS DERVIVED FROM SPECIFIC REGIONS OF THE LONGITUDINAL AXIS OF THE HIPPOCAMPUS ICVS Neuroconferences workshop, Braga [Details]
(2015)New Horizons – Translational Research Conference
Cussotto S, Cryan JF, O’Leary OF (2015) ELUCIDATION OF THE NEURONAL CIRCUITRY UNDERLYING THE ANTIDEPRESSANT EFFECTS OF A MEDICATION USE New Horizons – Translational Research Conference [Details]
(2015)New Horizons – Translational Research Conference
James D. O'Leary, Danka A. Kozareva, Cara M. Hueston, Olivia F. O'Leary, John F. Cryan, Yvonne M. Nolan (2015) The nuclear receptor TLX regulates motor, cognitive and anxiety-related behaviours during adolescence and adulthood New Horizons – Translational Research Conference [Details]
(2015)European Behavioural Pharmacology Society
James D. O'Leary, Danka A. Kozareva, Cara M. Hueston, Olivia F. O'Leary, John F. Cryan and Yvonne M. Nolan (2015) THE NUCLEAR RECEPTOR TLX REGULATES MOTOR, COGNITIVE AND ANXIETY-RELATED BEHAVIOURS DURING ADOLESCENCE AND ADULTHOOD European Behavioural Pharmacology Society Verona, Italy, , 12-SEP-15 - 15-SEP-15 [Details]
(2015)Society for Neuroscience
Ramos Costa AP, Levone BR, Lino-de-Oliveira C, Dinan TG, O’Leary OF, Monteiro de Lima TC, Cryan JF. (2015) Hippocampal neuronal activation and neurogenesis in a pharmacological model of anxiety Society for Neuroscience [Details]
(2014)Careers in Neuroscience Symposium, Arts Millennium Building, NUI Galway
Crowley T, Cryan JF, Downer EJ, O'Leary OF (2014) Investigation of the GABAB receptor as a modulator of central and peripheral inflammation Careers in Neuroscience Symposium, Arts Millennium Building, NUI Galway [Details]
(2014)Frontiers in Neurology, 4th Annual meeting, Science Gallery, Trinity College Dublin
Crowley T, Fitzpatrick JM, O’Toole O, Cryan JF, O'Leary OF and Downer EJ (2014) An investiagtion into baclofen as a modulator of central TLR3/TLR4 signalling Frontiers in Neurology, 4th Annual meeting, Science Gallery, Trinity College Dublin [Details]
(2014)Society for Neuroscience
G. MOLONEY, O. O' LEARY, L. DESBONNET, F. SHANAHAN, T. G. DINAN, G. CLARKE, J. F. CRYAN (2014) Microbiota regulates microRNA expression in the hippocampus in a sex dependent manner Society for Neuroscience [Details]
(2014)27th ECNP Congress of Applied and Translational Neuroscience, Berlin, Germany
O'Leary OF (Invited Talk) (2014) 'GABAB1 receptor subunit isoforms differentially modulate resilience to stress 27th ECNP Congress of Applied and Translational Neuroscience, Berlin, Germany [Details]
(2014)27th ECNP Congress of Applied and Translational Neuroscience, Berlin, Germany
Ogbonnaya E.S, Lyons M, Clarke G, Shanahan F, Dinan, T.G., Cryan J.F., O’Leary O.F (2014) The microbiota-gut-brain axis regulates adult hippocampal neurogenesis 27th ECNP Congress of Applied and Translational Neuroscience, Berlin, Germany [Details]
(2014)Neuroscience Ireland Young Neuroscientists Symposium 2014
James D. O’Leary, Cara M. Hueston, Danka Kozareva, Olivia F. O’Leary John F. Cryan, and Yvonne M. Nolan (2014) Role of the nuclear receptor TLX in cognition during adolescence and adulthood Neuroscience Ireland Young Neuroscientists Symposium 2014 Trinity Biomedical Sciences Institute, Trinity College Dublin, , 20-SEP-14 [Details]
(2013)Neuroscience Ireland Conference 2013
Bonetti M., O’Connor R.M., Riva M., Cryan J.F., O’Leary O.F. (2013) Do antidepressants affect hippocampal GABAB receptor expression? Neuroscience Ireland Conference 2013 [Details]
(2013)Neuroscience Ireland Conference 2013
Ogbonnaya E.S., Felice D., Cryan J.F., O’Leary O.F. (2013) The vagus nerve tonically regulates the proliferation and survival of newly-born cells in the adult hippocampus Neuroscience Ireland Conference 2013 [Details]
(2013)International Behavioural Neuroscience Society Annual Meeting, Dublin, 25th -30th June 2013
Ogbonnaya S., Clarke G., Shanahan, F., Dinan T.G., Cryan, J. F., O’Leary, O.F. (2013) The microbiome-gut-brain axis regulates the survival of newly-born cells in the adult hippocampus International Behavioural Neuroscience Society Annual Meeting, Dublin, 25th -30th June 2013 [Details]
(2013)International Behavioural Neuroscience Society Annual Meeting, Dublin, 25th -30th June 2
O'Leary OF (Invited Talk) (2013) GABAB1 receptor subunit isoforms modulate susceptibility and resilience to stress-induced changes in behaviour: Implications for gene x environment interactions in depression and anxiety disorders International Behavioural Neuroscience Society Annual Meeting, Dublin, 25th -30th June 2 [Details]
(2013)Royal Academy of Medicine in Ireland, Section of Biomedical Sciences, University College Cork, June 20th
Ogbonnaya S., Clarke G., Shanahan F., Cryan J. F., O’Leary, O.F. (2013) Establishment of the gut microbiome during early-life influences the survival of newly-born cells in the adult hippocampus Royal Academy of Medicine in Ireland, Section of Biomedical Sciences, University College Cork, June 20th [Details]
(2012)25th European Collge of Neuropsychopharmacology congress, Vienna, Austria
Felice D., O'Leary O.F., Bettler B., Cryan J.F. (2012) GABAB(1) receptor subunit isoforms differentially mediate susceptibility to early-life stress-induced depression related behaviour 25th European Collge of Neuropsychopharmacology congress, Vienna, Austria [Details]
(2012)All Ireland Pharmacy Schools Conference, Cork, Ireland
Felice D., O'Leary O.F., Bettler B., Cryan J.F. (2012) GABAB receptor subunit isoforms differentially mediate susceptibility to early-life stress-induced depression related behaviour All Ireland Pharmacy Schools Conference, Cork, Ireland [Details]
(2012)ECNP Workshop on Neuropsychopharmacology, March 15-18 2012, Nice, France
Felice D, O’Leary O.F, Bettler B, Cryan JF (2012) GABAB(1) Receptor Subunit Isoforms Differentially Mediate Susceptibility to Depression-Related Behaviour Following Early-Life Stress ECNP Workshop on Neuropsychopharmacology, March 15-18 2012, Nice, France [Details]
(2011)Wiring the brain: Making connections, Wicklow, Ireland
O'Leary OF, Zandy S, Dinan TG, and Cryan JF; (2011) Increased hippocampal cell proliferation as a molecular mechanism for the therapeutic efficacy of adjunctive lithium therapy in treatment-resistant depression Wiring the brain: Making connections, Wicklow, Ireland [Details]
(2011)Anxiety and Depression, 21st Neuropharmacology Conference, Virginia, USA
Felice D, O'Leary OF, Bettler B, Cryan JF; (2011) The role of GABAB(1) receptor subunits in the modulation of early life stress on anxiety and depression-related behaviour in adulthood Anxiety and Depression, 21st Neuropharmacology Conference, Virginia, USA [Details]
(2011)Neuropharmacology Conference, Virginia, USA, November 10-11
Felice D, O'Leary OF, Pizzo RC, Cryan JF; (2011) Adult hippocampal neurogenesis is increased by a GABAB receptor antagonist : Relevance to antidepressant action Neuropharmacology Conference, Virginia, USA, November 10-11 [Details]
(2011)Anxiety and Depression, 21st Neuropharmacology Conference, Virginia, USA
O'Leary OF, Savignac HM, Felice D., Bettler B., Cryan JF; (2011) GABAB(1) receptor isoforms confer differential susceptibility to the effects of social defeat stress Anxiety and Depression, 21st Neuropharmacology Conference, Virginia, USA [Details]
(2011)European Behavioural Pharmacology society, Amsterdam
O'Leary OF, Zandy S, Dinan TG, and Cryan JF ; (2011) Adjunctive lithium treatment has antidepressant-like behavioural effects and increases hippocampal neurogenesis in a model of treatment-resistant depression European Behavioural Pharmacology society, Amsterdam [Details]
(2011)Health Research Board Watts Medal Competition
O'Mahony E, O'Leary OF, McKernan DP, O¿Malley D, Dinan TG and Cryan JF ; (2011) Investigation of glycogen synthase kinase-3 as a biomarker of schizophrenia and early-life stress Health Research Board Watts Medal Competition [Details]
(2011)Anxiety and Depression, 21st Neuropharmacology Conference, Virginia, USA
O'Leary OF, Zandy S, Dinan TG, Cryan JF; (2011) Adjunctive lithium treatment has antidepressant-like behavioural effects and increases adult hippocampal neurogenesis in a mouse model of treatment resistance Anxiety and Depression, 21st Neuropharmacology Conference, Virginia, USA [Details]
(2011)The International College of Neuropsychopharmacology (CINP) thematic meeting: Polypharmacy: The Good, The Bad and The Ugly, Salzburg, Austria
O'Leary OF, Zandy S, Dinan TG and Cryan JF; (2011) Increased hippocampal cell proliferation as a molecular mechanism for the therapeutic efficacy of adjunctive lithium therapy in treatment-resistant depression The International College of Neuropsychopharmacology (CINP) thematic meeting: Polypharmacy: The Good, The Bad and The Ugly, Salzburg, Austria [Details]
(2011)Neuroscience Ireland
Felice D., O'Leary O.F., Bettler B., Cryan J.F. (2011) The role of GABAB(1) receptor subunits in the modulation of the effects of early life stress on anxiety and depression-related behaviour in adult mice Neuroscience Ireland [Details]
(2011)Neuroscience Ireland
Felice D., O'Leary O.F., Pizzo R.C., Cryan J.F. (2011) Adult hippocampal neurogenesis is increased by a GABAB receptor antagonist in BALB/c mice: Relevance to antidepressant action Neuroscience Ireland [Details]
(2010)European College of Neuropsychopharmacology (ECNP) congress, Amsterdam, The Netherlands
O'Leary OF, O¿Connor RM, and Cryan JF; (2010) Lithium preferentially increases neurogenesis in the ventral but not dorsal hippocampus of stressed BALB/c mice European College of Neuropsychopharmacology (ECNP) congress, Amsterdam, The Netherlands [Details]
(2010)7th World Congress on Stress Leiden, The Netherlands
O'Leary OF, O¿Connor RM and Cryan JF; (2010) Desipramine differentially regulates antidepressant-like behaviour and the HPA axis in stressed BALB/c mice 7th World Congress on Stress Leiden, The Netherlands [Details]
(2010)European Behavioural Pharmacology Society, Workshop on drugs, psychiatric disorders and neurogenesis, Tours, France
O'Leary OF, O¿Connor RM, McGrath B and Cryan JF; (2010) Lithium-induced increases in cell proliferation are restricted to the ventral hippocampus in stressed BALB/c mice: Relationship to cell survival European Behavioural Pharmacology Society, Workshop on drugs, psychiatric disorders and neurogenesis, Tours, France [Details]
(2010)Society for Neuroscience annual meeting, San Diego, CA, USA
O'Leary OF, O¿Connor RM, McGrath B and Cryan JF; (2010) Distinguishing the roles of the ventral versus dorsal hippocampus in stress and lithium-induced changes in cell turnover Society for Neuroscience annual meeting, San Diego, CA, USA [Details]
(2010)6th Euron Workshop Drugs and the Brain: an update in Psychopharmacology, Braga, Portugal
O'Connor RM, O'Leary OF, Dinan A, Gokul A, Grenham S, Dinan TG and Cryan JF; (2010) Stress-induced Alterations in Hippocampal and Amygdalar microRNAs: Effects of Lithium 6th Euron Workshop Drugs and the Brain: an update in Psychopharmacology, Braga, Portugal [Details]
(2010)European Behavioural Pharmacology Society, Workshop on drugs, psychiatric disorders and neurogenesis, Tours, France
Felice D, O'Leary OF, Sweeney F, Pizzo R and Cryan J; (2010) GABAB receptor blockade induces antidepressant-like behavioural effects: Relationship with neurogenesis European Behavioural Pharmacology Society, Workshop on drugs, psychiatric disorders and neurogenesis, Tours, France [Details]
(2010)Neuroscience Ireland Annual Conference, University College Dublin
Pizzo RC, O'Leary OF and Cryan JF; (2010) The medial prefrontal cortex contributes to the anxiolytic effects of the GABAB receptor positive modulator GS39783 Neuroscience Ireland Annual Conference, University College Dublin [Details]
(2010)ECNP workshop on psychopharmacolgy for young scientists, Nice, France
O'Connor RM, O'Leary OF, Dinan A, Gokul A, Grenham S, Dinan TG and Cryan JF; (2010) Stress-induced alterations in hippocampal microRNAs: effects of lithium ECNP workshop on psychopharmacolgy for young scientists, Nice, France [Details]
(2009)Society for Neuroscience, Chicago
Bravo JA, O'Leary OF, Dinan TG and Cryan JF; (2009) Altered stress-related gene expression in the amygdala of a genetic model of anxiety and depression Society for Neuroscience, Chicago [Details]
(2009)European Behavioural Pharmacology Society, Rome, Italy
Sweeney F, O'Leary OF and Cryan J; (2009) GABAB receptor activation during early adolescence affects adult anxiety behaviour European Behavioural Pharmacology Society, Rome, Italy [Details]
(2009)Neuroscience Ireland Annual Conference, Dublin
Sweeney F, O'Leary OF and Cryan JF ; (2009) GABAB receptor activation during early adolescence affects adult anxiety behaviour Neuroscience Ireland Annual Conference, Dublin [Details]
(2009)Neuroscience Ireland Annual Conference, Dublin
O'Leary OF, Wu X and Castren, E; (2009) The antidepressant fluoxetine increases expression of synaptic proteins in the hippocampus of a model of reduced hippocampal synapse density Neuroscience Ireland Annual Conference, Dublin [Details]
(2009)European Behavioural Pharmacology Society, Rome, Italy
O'Leary OF, O'Connor R and Cryan JF; (2009) Lithium increases hippocampal cell proliferation and alters behaviour in a high anxiety mouse strain: Effects of chronic immobilization stress European Behavioural Pharmacology Society, Rome, Italy [Details]
(2009)Neuroscience Ireland Annual Conference, Dublin
O'Leary OF, O'Connor R and Cryan JF; (2009) Lithium increases hippocampal cell proliferation and alters behaviour in a high anxiety mouse strain: Effects of chronic immobilisation stress Neuroscience Ireland Annual Conference, Dublin [Details]
(2008)Society for Neuroscience, Washington D.C., USA
O'Leary OF, Wu X and Castren E; (2008) Chronic fluoxetine treatment increases expression of synaptic proteins in the hippocampus of a model of reduced hippocampal synapse density Society for Neuroscience, Washington D.C., USA [Details]
(2008)Federation of European Neuroscience Societies (FENS)
Maya Vetencourt JF, Sale A, Viegi A, De Pasquale R, Baroncelli L, O'Leary O, Castrén E and Maffei L; (2008) Chronic fluoxetine administration restores plasticity in the adult visual cortex Federation of European Neuroscience Societies (FENS) [Details]
(2006)Federation of European Neuroscience Societies (FENS), Vienna, Austria
O'Leary OF, Sairanen M and Castren E; (2006) Chronic antidepressant treatment increases expression of plasticity-associated proteins in the hippocampus and prefrontal cortex Federation of European Neuroscience Societies (FENS), Vienna, Austria [Details]
(2006)Society for Neuroscience, Atlanta, Georgia, USA
Castren E, Rantamaki TR, Sairanen M and O'Leary OF.; (2006) Antidepressants rapidly activate TrkB neurotrophin signaling and gradually increase the expression of plasticity-associated proteins in the rodent anterior cingulate cortex and hippocampus Society for Neuroscience, Atlanta, Georgia, USA [Details]
(2003)Society for Neuroscience, New Orlean, Louisiana, USA
O'Leary OF and Lucki I.; (2003) The Role of alpha1-adrenoceptors in the mechanism of action of antidepressants Society for Neuroscience, New Orlean, Louisiana, USA [Details]
(2002)Society for Neuroscience, Orlando, Florida, USA
O'Leary OF, Cryan JF, Page ME, Hirsch BR, Thomas SA and Lucki I; (2002) Reduced sensitivity to the behavioral and neurochemical effects of SSRIs in norepinephrine-deficient mice Society for Neuroscience, Orlando, Florida, USA [Details]
(2001)Society for Neuroscience, San Diego, California, USA
O'Leary OF, Page ME, Hirsch BR, Thomas SA, Cryan JF and Lucki I. ; (2001) Role of serotonin in the antidepressant-like effects of SSRIs in the tail suspension test Society for Neuroscience, San Diego, California, USA [Details]

Professional Activities

Honours and Awards

 YearTitleAwarding Body
2020ECNP Citation Award European College of Neuropsychopharmacology (ECNP)
2015Most Outstanding Junior Faculty Travel Award International Behavioural and Neural Genetics Society (IBANGS)
20112011 Rafaelsen Young Investigator Award International College of Neuropsychopharmacology
20102010 ECNP Fellowship Award European College of Neuropsychopharmacology
2008HRB Career development Award Health Research Board Ireland
2009Oral presentation prize Neuroscience ireland
2010Poster prize Euron Workshop
1995University Scholarship Department of Education

Professional Associations

 AssociationFunctionFrom / To
European Behavioural Pharmacology Society (EBPS) member/
Society for Neuroscience (SFN) Member/
Neuroscience Ireland Member/
Biolink USA-Ireland Member/

Conference Contributions

 YearPublication
(2015)Trinity College Dublin, Neuroscience Society,
Olivia F. O'Leary (2015) Role of adult hippocampal neurogenesis and the GABAB receptor in stress resilience. [Invited Seminars/Guest Lectures], Trinity College Dublin, Neuroscience Society, Trinity College Dublin, . [Details]
(2015)New Horizons – Translational Research Conference,
Levone BR, O’Leime C, Nolan YM, Cryan JF, O’Leary, OF (2015) Corticosterone differentially affects neural progenitor cells derived from specific areas of the longitudinal axis of the hippocampus. [Invited Lectures (Conference)], New Horizons – Translational Research Conference, Ireland . [Details]
(2014)Neuroscience Ireland Young Neuroscientists Symposium,
O’Leary JD, Hueston CM, Kozareva D, O’Leary OF, Cryan JF, Nolan YM (2014) Role of the nuclear receptor TLX in cognition during adolescence and adulthood. [Invited Lectures (Conference)], Neuroscience Ireland Young Neuroscientists Symposium, Trinity College Dublin . [Details]
(2015)Colston Research Symposium New developments in PTSD research and treatment,
O'Leary OF (Invited Talk) (2015) Role of GABA in stress resilience. [Invited Lectures (Conference)], Colston Research Symposium New developments in PTSD research and treatment, Bristol, United Kingdom , 16-NOV-15 - 17-NOV-15. [Details]
(2015)17th Annual Genes, Brain & Behaviour Meeting (IBANGS),
O'Leary OF (2015) GABAB(1) receptor subunit isoforms differentially regulate stress resilience. [Invited Lectures (Conference)], 17th Annual Genes, Brain & Behaviour Meeting (IBANGS), Uppsala, Sweden , 19-MAY-15 - 22-JUL-15. [Details]
(2014)Updates in Psychiatry Meeting,
Olivia F. O'Leary (2014) Towards New Antidepressant Therapeutic Strategies. [Invited Seminars/Guest Lectures], Updates in Psychiatry Meeting, University College Cork, Ireland , 24-APR-14 - 24-APR-14. [Details]
(2014)27th ECNP Congress,
Olivia F. O'Leary (2014) GABAB1 receptor subunit isoforms differentially modulate resilience to stress. [Invited Lectures (Conference)], 27th ECNP Congress, Berlin, Germany , 21-OCT-14. [Details]
(2013)International Behavioural Neuroscience Society Annual Meeting,
O'Leary O.F. (2013) GABAB1 receptor subunit isoforms modulate susceptibility and resilience to stress-induced changes in behaviour: Implications for gene x environment interactions in depression and anxiety disorders. [Invited Lectures (Conference)], International Behavioural Neuroscience Society Annual Meeting, Dublin , 25-JUN-13 - 30-JUL-13. [Details]
(2009)Neuroscience Ireland Annual meeting,
O'Leary OF (2009) The antidepressant fluoxetine increases expression of synaptic proteins in the hippocampus of a model of reduced hippocampal synapse density. [Invited Oral Presentation], Neuroscience Ireland Annual meeting, Science Gallery, Dublin, Ireland . [Details]

Committees

 CommitteeFunctionFrom / To
Academic Council Graduate Studies Committee (ACGSC) Member2023 /
University Animal Ethics Experimentation Committee Member2015 / 2020
College of SEFS Board of Studies for BSc Biological and Chemical Sciences Member2023 /
College of Medicine and Health (COMH) Graduate studies Committee Member2023 /
College of SEFS Teaching Learning Student Engagement (TLSE) Committee Member2023 /
College of SEFS Academic Programmes and Curriculum Development (APCD) Committee Member2023 /
College Council of SEFS Department of Anatomy & Neuroscience Representative2023 /
School of Medicine Research & Postgraduate affairs Committee Member2017 / 2023
BSc Neuroscience Programme Board Chair2023 /
BSc Paramedic Studies Programme Board Member2017 /
BEd Physical Education, Sports Studies & Arts Programme Board Member2012 / 2023
MSc Molecular Cell Biology with Bioinnovation Programme Board Member2016 / 2021
BSc Neuroscience Programme Board Member2012 /
Prehospital care working group Member2014 / 2016
Departmental Graduate Studies Committee Chair2013 / 2023
Departmental Graduate Studies Committee Member2012 /
Departmental Research & Innovation Committee Member2023 / 2024
Departmental Teaching & Learning Committee Member2023 /
Departmental Representative for Disability Awareness Departmental Representative2013 /
Health & Safety Committee, School of Pharmacy, University College Cork Member2011 / 2012

Employment

 EmployerPositionFrom / To
School of Pharmacy, Dept. of Pharmacology and Therapeutics, University College Cork Lecturer01-AUG-11 /
University College Cork HRB Career development Award/Senior Postdoctoral Fellow01-OCT-08 / 31-AUG-11
Neuroscience Centre, University of Helsinki, Finland Postdoctoral Fellow31-AUG-05 / 31-JUL-08
University of Pennsylvania, USA Visiting Scholar08-JAN-01 / 15-JUL-05

Education

 YearInstitutionQualificationSubject
2015University College Cork Certificate in Teaching and Learning in Higher EduTeaching
2005National University of Ireland, Galway PhDPharmacology
2001National University of Ireland, Galway MScNeuropharmacology
1999National University of Ireland, Galway BSc HonsBiotechnology
1997National University of Ireland, Galway DIPLOMAGaeilge

Journal Activities

 JournalRoleTo / From
Acta Neuropsychiatrica Member of Editorial Board01-JAN-17 -
Archives Of Microbiology Referee-
Behavioural Pharmacology Member of Editorial Board01-APR-22 -
Brain Organoid And System Neuroscience Member of Editorial Board01-JAN-23 -
Neurobiology Of Stress Member of Editorial Board01-APR-23 -
Neuropharmacology Member of Editorial Board01-APR-16 -
Pharmacological Research – Reports Member of Editorial Board01-JAN-23 -
Neuronal Signaling Guest Editor01-AUG-21 -
Acs Chemical Neuroscience Referee-
Advances In Medical Sciences Referee-
Animal Behaviour Referee-
Archives Of Women'S Mental Health Referee-
Behavioural Brain Research Referee-
Behavioural Pharmacology Referee-
Biochemical Pharmacology Referee-
Biological Psychiatry Referee-
Biologia Referee-
Biological Psychology Referee-
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie Referee-
British Journal Of Pharmacology Referee-
Brain Behav Immun Referee-
Brain Research Referee-
Brain Research Bulletin Referee-
Brain Structure And Function Referee-
Cell Reports Referee-
Cns Spectrums Referee-
Computers In Human Behavior Referee-
Current Medicinal Chemistry Referee-
Current Opinion In Physiology Referee-
Developmental Psychobiology Referee-
Digestive Diseases And Sciences Referee-
Drug And Chemical Toxicology Referee-
Drug Discovery Today Referee-
Elife Referee-
European Journal Of Neurology Referee-
European Journal Of Pharmacology Referee-
European Neuropsychopharmacology Referee-
European Archives Of Psychiatry And Clinical Neuroscience Referee-
European Journal Of Neuroscience Referee-
Evidence-Based Complementary And Alternative Medicine Referee-
Experimental And Clinical Psychopharmacology Referee-
Expert Opinion On Drug Discovery Referee-
Expert Opinion On Drug Metabolism & Toxicology Referee-
Expert Opinion On Therapeutic Patents Referee-
Frontiers In Behavioral Neuroscience Referee-
Frontiers In Neuroendocrinology Referee-
Frontiers In Neurology Referee-
Fundamental & Clinical Pharmacology Referee-
Genes, Brain And Behavior Referee-
Gut Microbes Referee-
Gut Microbes Reports Referee-
Hippocampus Referee-
Ibro Reports Referee-
Immunology Letters Referee-
International Journal Of Developmental Neuroscience Referee-
International Journal Of Neuropsychopharmacology Referee-
The International Journal Of Neuroscience Referee-
Journal Of Affective Disorders Referee-
Journal Of Neurochemistry Referee-
Journal Of Neuroimmunology Referee-
Journal Of Neuroscience Research Referee-
Journal Of Pharmacy And Pharmacology Referee-
Journal Of Chemical Neuroanatomy Referee-
Journal Of Neuroinflammation Referee-
Journal Of Neuroscience Referee-
Journal Of Psychiatric Research Referee-
Journal Of Psychopharmacology Referee-
Journal Of Visualized Experiments : Jove Referee-
Molecular And Cellular Neuroscience Referee-
Molecular Neurobiology Referee-
Molecular Psychiatry Referee-
Naunyn-Schmiedeberg'S Archives Of Pharmacology Referee-
Neural Plasticity Referee-
Neural Regeneration Research Referee-
Neurobiology Of Learning And Memory Referee-
Neurobiology Of Stress Referee-
Neurochemistry International Referee-
Neurological Research Referee-
Neuronal Signaling Referee-
Neuropharmacology Referee-
Neuropsychopharmacology Referee-
Neuroscience Referee-
Neuroscience And Biobehavioral Reviews Referee-
Nutritional Neuroscience Referee-
Pharmacology, Biochemistry, And Behavior Referee-
Physiology And Behaviour Referee-
Plos One Referee-
Proceedings Of The National Academy Of Sciences Of The United States Of America Referee-
Progress In Neuro-Psychopharmacology & Biological Psychiatry Referee02-APR-13 -
Psychiatry Research Referee-
Psychoneuroendocrinology Referee01-MAR-14 -
Psychopharmacology Referee-
Research Referee-
Scientific Reports Referee-
Synapse (New York, N.Y.) Referee-
Theranostics Referee-
Therapeutic Advances In Psychopharmacology Referee-
Translational Psychiatry Referee-
World Journal Of Neurology Referee-

Consultancy

 ClientDescription
Janssen
invited presentation

Other Activities

 Description

External Examiner

Undergraduate taught programmes:
BSc Applied Biology & Biopharmaceutical Science (2014-2020) ATU, Galway

PhD thesis examiner: 
  • Tata Institute of Fundamental Research (TIFR), India (2023)
  • Kings College London (2017, 2020) 
  • Dept of Psychiatry, University College Cork (2015, 2020)
  • Dept of Physiology, University College Cork (2019, 2022)
  • Dept of Anatomy & Neuroscience (2013, 2017, 2019, 2024)
  • NUI Maynooth (2015) 
  • Aarhus University, Denmark (2016) 
  • Trinity College Dublin (2015, 2018, 2018) 
  • School of Pharmacy University College Cork (2012, 2013, 2019)
  • Dept of Paediatrics, University College Cork (2019)

MSc by research thesis examiner:
  • Dept of Anatomy and Neuroscience (2019, 2023)
  • School of Pharmacy (2022) 


Reviewer of grant applications submitted to International Funding Agencies:
  • AIFA Italian Medicines agency (2019)
  • L'Agence Nationale del Recherche (ANR) France (2011, 2013)
  • Canada Foundation for Innovation (2021)
  • ERC consolidator Grants (2019)
  • ETH Zurich Research Grants (2023)
  • Fondation pour la recherche medicale (FRM) France (2015, 2019, 2020)
  • Health Research Council of New Zealand (2020)
  • Human Frontier Science Program Organisation (2024)
  • US-Israel Binational Science Foundation (2014)
  • KU Leuven, Belgium (2016, 2017)
  • Motor Neurone Disease association, UK (2020) 
  • Medical Research Council, UK (2015) 
  • National Science Centre Poland (2023, 2024, 2024) 
  • Expert review panel member for National Science Centre Poland (July – October 2023; lead reviewer for 16 applications; a total of 150 application assessed in the call) Preludium - NZ7)
  • Rosetrees trust, UK (2024) 
  • Netherlands organisation for Scientific research (2013)
  • Wellbeing of Women, UK (2014)
  • The Research Council of Norway (RCN) peer reviewer panel (2024-2027) 
  • UK Research and Innovation (2024)

Selection/Interview Panel Member:
  1. Senior Executive assistant, Biological Services Unit (2022) 
  2. Technical Assistant, Biological Services Unit (2019) 
  3. Lecturer in Anatomy (Physiotherapy) (2019) 
  4. Lectureship in Pharmaceutics, School of Pharmacy (2018)
  5. Technical Assistant, Biological Services Unit ( 2016) 
  6. Lectureship in Pharmaceutics, School of Pharmacy (2016) 
I have taken selection committee training (2015), training for Chairing UCC Selection Committees (2016) and Unconscious bias in recruitment selection (2023).

Teaching Activities

Teaching Interests

CURRENT POSTGRADUATE STUDENTS:
Amiee Cronin (2023-2026, PhD student)
Almas Khan (2022-2026, PhD student)
Ketki Mulay (2022-2026, PhD student)
Antonios Prosilis (2022-2026, PhD student)
Maria Caruso (2021-2025, PhD Student)

PROGRAMME DIRECTOR (2023-present):
BSc Neuroscience
Intercalated BSc  (Hons) Degree (Anatomy or Neuroscience) 

UNDERGRADUATE:
Module Coordinator & Lecturer:
AN1063 Anatomy of Exercise (Academic Years 2012-2023)
AN3004 Human regional neuroanatomy
AN4012 Medical imaging and biomedical devices in the neurosciences
AN4011 Research Project
AN4015 Work Placement
MD1205 Principles of Human Structure for Practitioner Paramedics
MD1206 Topographical Anatomy for Practitioner Paramedics
MD3012 Principles of Human Structure for Practitioner Paramedics
MD3015 Topographic Anatomy for Practitioner Paramedics   
MD2005 Principles of Human Structure for Practitioner Paramedics 
MD2006 Topographic Anatomy for Practitioner Paramedics   

Co-ordinator & Lecturer of Neuroanatomy component of:
AN2006 Neuroanatomy and embryology for dental students  
AN2060 Developmental neuroanatomy for occupational therapy
AN2061 Neuroanatomy and embryology for speech and language therapy

Lecturer:
AN4014 Cellular and Molecular Neuroscience
AN4013 Advanced Topics in Neuroscience
AN3011 Library Project (2023- )
AN3013 Neurobiololgy of Disease
AN2020 Introduction to Neuroscience, the Brain and Behaviour

Supervisor:
AN3011 Library project (2012 - 2021)
AN4011 Research Project (2012 - present)
MX5091 Research Project and Elective Practice

POSTGRADUATE:
MSc thesis Supervisor:
AN6010 Research Dissertation (MSc in Human Anatomy)
MB6303 Dissertation ( MSc Bioinformatics and Computational Biology)
ML6001 Molecular Cell Biology Research Dissertation (2015-2018)

Previous Teaching Contributions:
ML6002 Biological and Clinical Perspectives of Human Disease.

Prior to my appointment to my current position, I was a lecturer in pharmacology in the School of Pharmacy (UCC) and an ad-hoc lecturer in the Dept. of Pharmacology and Therapeutics (UCC) during which time I taught various aspects of pharmacology to Medical students (direct entry and graduate entry), Pharmacy students, Science students and Dental Hygiene students, and I supervised 4th Yr Pharmacy undergraduate research projects (PF4004 Pharmacy Project). I was module co-ordinator for two modules [PT4005 (Neuropharmacology), PT3445 (Systems Pharmacology)] and contributed to four other modules [FM3003 (Foundations of Medicine: Fundamentals of Therapy); PT3001 (Introduction to Pharmacology), PT4005 (Neuropharmacology), PT3445 (Systems Pharmacology)].

Recent Postgraduates

 Graduation YearStudent NameInstitutionDegree TypeThesis Title
2024Minke Nota University College CorkPHDPeripheral alterations underlying the negative effects of a cafeteria diet on brain and behaviour: exercise as a mitigating strategy
2022Katherine Guzzetta University College CorkPHDInvestigations on the Role of the Gut Microbiota in Hippocampal Neuroplasticity and Behaviour Throughout the Lifespan
2021Andrew McGovern University College CorkMscThe effects of stressors during early life on hippocampal neurogenesis and microglial activation in the male and female brain
2019Lauren Pawley University College CorkMscThe impact of Chronic Neuroinflammation on Adult and Adolescent Hippocampal Neurogenesis and on the Stressed Brain
2018Brunno R. Levone University College CorkPHDDifferential Roles of Specific Sub-Regions of the Longitudinal Axis of the Hippocampus in the Behavioural and Neurogenesis Responses to Stress and Antidepressant Drugs
2018James O'Leary UCCPHDAdolescence as a Vulnerable Period for the Effects of Intrinsic & Extrinsic Regulators of Neurogenesis on Cognitive Behaviour
2015Tadhg Crowley University College CorkMScTargeting the GABAB receptor in Neuroinflammation
2014Ebere Sunny Ogbonnaya University College CorkDoctor of MedicineAdult hippocampal neurogenesis and the gut-brain axis
2013Daniela Felice University College CorkPhDNovel Insights into the Role of the GABAB Receptor in Depression and Anxiety

Research Information

Internal Collaborators

 NameInstituteCountry
Prof Yvonne Nolan University College CorkIRELAND
Prof. John F. Cryan University College CorkIRELAND
Prof Ella Arensman
Dr Jane English
Prof Aonghus Lavelle
Prof Gerard Clarke
Prof Aideen Sullivan
Prof Cora O'Neill
Dr. Eric Downer University College CorkIRELAND
Prof. Ted Dinan University College CorkIRELAND

External Collaborators

 NameOrganisation / InstituteCountry
Dr. Malika El-Yacoubi University of LyonFRANCE
Prof. Bernhard Bettler University of BaselSWITZERLAND
Prof. Jean-Marie Vaugeois University of RouenFRANCE

Contact details

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Department of Anatomy and Neuroscience

Anatamaíocht agus Néareolaíocht

Room 2.33, 2nd Floor, Western Gateway Building, University College, Cork, Ireland

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