iEd Hub - Head
CancerResearch@UCC - Principal Investigator
APC Microbiome Ireland - Senior Investigator
- Connecting Industry & Academia: Together with leading industries in the Health & Life Sciences sector, we co-design and deliver novel postgraduate programmes that develop the future leaders of this sector. Programmes focus on operations and management, coupled with relevant technical skills. http://iedhub.ie
- Research interests include associations between bacteria and cancer, development of microbes as therapeutics, in silico protein design and microbiome. Worked for a number of years at various international institutions (Los Angeles, Boston, Copenhagen) and published extensively in the fields of bacterial engineering, microbiome and cancer.
See https://marktangney.wixsite.com/website
The iEd Hub is funded by €8.7 million awarded under the Government’s Human Capital Initiative Programme (HCI), designed to meet priority skills needs across Ireland’s economy. http://iedhub.ie
- Research-led Teaching; e.g. iGEM http://2017.igem.org/Team:UCC_Ireland#
Biography
Prof Mark Tangney BSc, PhD, MBAiEd Hub - Head
CancerResearch@UCC - Principal Investigator
APC Microbiome Ireland - Senior Investigator
- Connecting Industry & Academia: Together with leading industries in the Health & Life Sciences sector, we co-design and deliver novel postgraduate programmes that develop the future leaders of this sector. Programmes focus on operations and management, coupled with relevant technical skills. http://iedhub.ie
- Research interests include associations between bacteria and cancer, development of microbes as therapeutics, in silico protein design and microbiome. Worked for a number of years at various international institutions (Los Angeles, Boston, Copenhagen) and published extensively in the fields of bacterial engineering, microbiome and cancer.
Research Interests
'BioEngineering next generation biomedical products': Primary focus is the development of novel technologies (therapeutic and diagnostic) for use in cancer medicine. Research is translational and commercially focused, and developed by our team of international scientists and clinicians skilled in cancer research, synthetic biology and bioinformatics.See https://marktangney.wixsite.com/website
Research Grants
| Project | Funding Body | Start Date | End Date | Award | |
|---|---|---|---|---|---|
| Vaccines and Imaging Partnership. | European Union | 01-OCT-14 | 30-SEP-18 | €787,013.00 | |
| EU H2020 MSCA CoFund 101034270 INSPIRE Shukla Arpit | Horizon 2020 | 01-OCT-24 | 31-DEC-26 | €98,268.00 | |
| SFI 18/SP/3522 'Precision Oncology Ireland' IND Mark Tangney [X] | SFI Industry | 01-SEP-19 | 28-FEB-26 | €323,604.00 | |
| Effect of Bacterial Membrane Vesicles Released by Human Gut Microbiota on Cancer | Irish Funded Research Non Exchequer | 06-JAN-20 | 05-NOV-22 | €63,333.00 | |
| Science Foundation of Ireland | 01-SEP-19 | 28-FEB-26 | €420,015.00 | ||
| Edible Probiotics as Cancer Theranostics. | Science Foundation of Ireland | 01-OCT-16 | 30-SEP-20 | €605,767.00 | |
| LITE: Live Imaging with Targeting Enzymes. | Science Foundation of Ireland | 01-JAN-17 | 30-APR-18 | €125,458.00 | |
| Bacteria in Human Tumours. | Health Research Board | 01-NOV-16 | 31-OCT-19 | €125,950.00 | |
| Development of Novel Bacterial Imaging Probes. | Science Foundation of Ireland | 01-JAN-13 | 31-MAR-14 | €108,313.00 | |
| Market Analysis for Novel Biological Cancer Theraeutic. | Enterprise Irl | 12-AUG-13 | 13-DEC-13 | €15,041.00 | |
| Bactria in Patient Tumours - What, Where and How? | Irish Research Council | 01-OCT-16 | 30-SEP-19 | €72,000.00 | |
| Adeno-Associated Virus as a vector for immune gene therapy of solid tumours | Science Foundation Ireland | 01-OCT-06 | 30-SEP-09 | €127,000.00 | |
| SFI-Listeria monocytogenes as a vector for cancer gene therapy | Science Foundation of Ireland | 16-JUL-07 | 15-AUG-08 | €86,650.00 | |
| Clinical development of a tumour diagnostic/therapeutic system utilising non-pathogenic bacteria. | Health Research Board | 01-JAN-11 | 31-AUG-14 | €251,140.00 | |
| Combined biotherapeutics for the treatment of metastatic cancer. | Irish Funded Research Non Exchequer | 01-OCT-11 | 30-MAR-15 | €190,824.00 | |
| HRB 'Bifidobacteria Mediated Cancer Gene Therapy' | Health Research Board | 01-OCT-07 | 30-JUN-11 | €289,944.00 | |
| Development of a Novel Vector for Cancer Gene Therapy for Clinical Application | European Framework Programme Seven (FP7) | 01-MAY-10 | 31-OCT-12 | €283,465.00 | |
| CRI "Anti-angiogenic Gene Therapy for Breast Cancer" | Miscellaneous Non Exchequer | 30-APR-08 | 01-MAY-11 | €195,332.00 | |
| SFI"Public Awareness on Genetic Modification" Supplement Teacher Cian O'Mahony | Science Foundation of Ireland | 20-JUN-08 | 15-AUG-08 | €11,639.00 | |
| Anamate: A Web Based Tool For The Easy Creation Of Flash Animations | Enterprise Ireland | 01-JAN-08 | 31-DEC-08 | €90,000.00 | |
| Long-term, systemic antitumour immunity via local, non-viral gene therapy of malignant tumours | Health Research Board | 01-OCT-05 | 30-SEP-08 | €275,000.00 | |
| Online Software For Generating Scientific Research Multimedia Animations | Enterprise Ireland | 01-JAN-07 | 31-DEC-07 | €82,015.00 | |
| Travel Support. | Enterprise Irl | 29-MAY-12 | 23-OCT-12 | €2,354.00 | |
| Bacterial-mediated Therapy of Prostatic Tumours. | Irish Funded Research Non Exchequer | 01-DEC-12 | 30-SEP-16 | €211,664.00 | |
| consumable budget only from R12305 | Health Research Board | 01-OCT-12 | 31-DEC-15 | €51,000.00 | |
| Probiotic Bacterial Trafficking to Tumours in Cancer Patients. | Health Research Board | 01-OCT-12 | 30-SEP-15 | €273,093.00 | |
| Commercialisation of Bacterial Imaging Technology. | Science Foundation of Ireland | 01-MAY-14 | 31-AUG-14 | €31,842.00 | |
| Immune Reactivity To Foregut Cancers; Investigation Into Mechanism Of Oral Tolerance | Irish Cancer Society | 01-OCT-06 | 30-SEP-09 | €176,000.00 | |
| Probiotic Bacteria in Cancer Medicine | Health Research Board | 06-JUN-16 | 27-JUL-16 | €2,000.00 | |
| A software tool for visualisation & co-ordination of research data | Enterprise Irl | 01-OCT-08 | 30-SEP-09 | €96,535.00 | |
| SFI "Public Awareness on Genetic Modification" Supplement Teacher Dan O'Sullivan | Science Foundation of Ireland | 20-JUN-08 | 15-AUG-08 | €14,744.00 | |
| Bacteria, Tumours and Imaging. | Science Foundation of Ireland | 01-JUN-15 | 31-AUG-15 | €35,195.00 |
Publications
Peer Reviewed Journals
| Year | Publication | |
|---|---|---|
| (2024) | 'Synthetic protein protease sensor platform' Devoy C;Flores Bueso Y;Buckley S;Walker S;Tangney M; (2024) 'Synthetic protein protease sensor platform'. Frontiers In Bioengineering And Biotechnology, 12 [DOI] [Details] | |
| (2023) | 'Fluorescence Lifetime Macro Imager for Biomedical Applications' Sen R;Zhdanov AV;Devoy C;Tangney M;Hirvonen LM;Nomerotski A;Papkovsky DB; (2023) 'Fluorescence Lifetime Macro Imager for Biomedical Applications'. Journal of visualized experiments : JoVE, (194) [DOI] [Details] | |
| (2023) | 'Analysis of tumour oxygenation in model animals on a phosphorescence lifetime based macro-imager' Zhdanov AV;Sen R;Devoy C;Li L;Tangney M;Papkovsky DB; (2023) 'Analysis of tumour oxygenation in model animals on a phosphorescence lifetime based macro-imager'. Scientific Reports, 13 (1) [DOI] [Details] | |
| (2023) | 'Fusobacterium nucleatum: a novel immune modulator in breast cancer?' Little A;Tangney M;Tunney MM;Buckley NE; (2023) 'Fusobacterium nucleatum: a novel immune modulator in breast cancer?'. Expert Reviews in Molecular Medicine, 25 [DOI] [Details] | |
| (2022) | 'An Overview of Alphafold's Breakthrough' Marcu SB;Tabîrca S;Tangney M; (2022) 'An Overview of Alphafold's Breakthrough'. Frontiers In Artificial Intelligence, 5 [DOI] [Details] | |
| (2022) | 'Understanding and harnessing triple-negative breast cancer-related microbiota in oncology' Devoy, C;Bueso, YF;Tangney, M (2022) 'Understanding and harnessing triple-negative breast cancer-related microbiota in oncology'. Frontiers In Oncology, 12 [DOI] [Details] | |
| (2022) | 'Identification of the Antigens Recognised by Colorectal Cancer Patients Using Sera from Patients Who Exhibit a Crohn's-like Lymphoid Reaction' Boncheva, VB;Linnebacher, M;Kdimati, S;Draper, H;Orchard, L;Mills, KI;O'Sullivan, G;Tangney, M;Guinn, BA (2022) 'Identification of the Antigens Recognised by Colorectal Cancer Patients Using Sera from Patients Who Exhibit a Crohn's-like Lymphoid Reaction'. Biomolecules, 12 [DOI] [Details] | |
| (2021) | 'Arming Yourself for The In Silico Protein Design Revolution' Walker, SP;Yallapragada, VVB;Tangney, M (2021) 'Arming Yourself for The In Silico Protein Design Revolution'. Trends In Biotechnology, 39 :651-664 [DOI] [Details] | |
| (2021) | 'Biopsy bacterial signature can predict patient tissue malignancy' Hogan G;Eckenberger J;Narayanen N;Walker SP;Claesson MJ;Corrigan M;O'Hanlon D;Tangney M; (2021) 'Biopsy bacterial signature can predict patient tissue malignancy'. Scientific Reports, 11 (1) [DOI] [Details] | |
| (2021) | 'Pepblock Builder VR - An Open-Source Tool for Gaming-Based Bio-Edutainment in Interactive Protein Design' Yallapragada VVB;Xu T;Walker SP;Tabirca S;Tangney M; (2021) 'Pepblock Builder VR - An Open-Source Tool for Gaming-Based Bio-Edutainment in Interactive Protein Design'. Frontiers In Bioengineering And Biotechnology, 9 [DOI] [Details] | |
| (2020) | 'Seeding sustainable education in developing countries: Teaching biotech in low-income areas' Flores Bueso Y.;Tangney M. (2020) 'Seeding sustainable education in developing countries: Teaching biotech in low-income areas'. Embo Reports, [DOI] [Details] | |
| (2020) | 'Protoblock - A biological standard for formalin fixed samples' Flores Bueso Y.;Walker S.P.;Hogan G.;Claesson M.J.;Tangney M. (2020) 'Protoblock - A biological standard for formalin fixed samples'. Microbiome, 8 (1) [DOI] [Details] | |
| (2020) | 'A novel cell permeability assay for macromolecules' Flores Bueso Y;Walker S;Quinn J;Tangney M; (2020) 'A novel cell permeability assay for macromolecules'. Bmc Molecular And Cell Biology, 21 (1) [DOI] [Details] | |
| (2020) | 'Function2Form Bridge – Towards synthetic protein holistic performance-prediction' Yallapragada, V. V. B.; Walker, Sidney P.; Devoy, Ciaran; Buckley, Stephen; Flores, Yensi; Tangney, Mark (2020) 'Function2Form Bridge – Towards synthetic protein holistic performance-prediction'. Proteins-Structure Function and Bioinformatics, 88 (3):462-475 [DOI] [Full Text] [Details] | |
| (2020) | 'Characterization of FFPE-induced bacterial DNA damage and development of a repair method' Flores Bueso Y;Walker SP;Tangney M; (2020) 'Characterization of FFPE-induced bacterial DNA damage and development of a repair method'. Biology Methods & Protocols, 5 (1) [DOI] [Details] | |
| (2020) | 'Non-specific amplification of human DNA is a major challenge for 16S rRNA gene sequence analysis' Walker, SP;Barrett, M;Hogan, G;Bueso, YF;Claesson, MJ;Tangney, M (2020) 'Non-specific amplification of human DNA is a major challenge for 16S rRNA gene sequence analysis'. Scientific Reports, 10 [DOI] [Details] | |
| (2020) | 'Sequence-Based Characterization of Intratumoral Bacteria—A Guide to Best Practice' Walker S.P.;Tangney M.;Claesson M.J. (2020) 'Sequence-Based Characterization of Intratumoral Bacteria—A Guide to Best Practice'. Frontiers in Oncology, 10 [DOI] [Details] | |
| (2019) | 'Microbiome analysis as a platform R&D tool for parasitic nematode disease management' Hogan G.;Walker S.;Turnbull F.;Curiao T.;Morrison A.;Flores Y.;Andrews L.;Claesson M.;Tangney M.;Bartley D. (2019) 'Microbiome analysis as a platform R&D tool for parasitic nematode disease management'. ISME Journal, [DOI] [Details] | |
| (2019) | 'ODX: A Fitness Tracker-Based Device for Continuous Bacterial Growth Monitoring' Yallapragada, V. V. B.,Gowda, U.,Wong, D.,O'Faolain, L.,Tangney, M.,Devarapu, G. C. R. (2019) 'ODX: A Fitness Tracker-Based Device for Continuous Bacterial Growth Monitoring'. Anal Chem, [DOI] [Details] | |
| (2018) | 'The Who, What, and Why of Drug Discovery and Development' Hogan G;Tangney M; (2018) 'The Who, What, and Why of Drug Discovery and Development'. Trends In Pharmacological Sciences, [DOI] [Details] | |
| (2018) | 'In situ biomolecule production by bacteria; A synthetic biology approach to medicine' Flores Bueso, Y.,Lehouritis, P.,Tangney, M. (2018) 'In situ biomolecule production by bacteria; A synthetic biology approach to medicine'. J Control Release, [Details] | |
| (2018) | 'Resident Bacteria in Breast Cancer Tissue: Pathogenic Agents or Harmless Commensals?' O'Connor, H;MacSharry, J;Bueso, YF;Lindsay, S;Kavanagh, EL;Tangney, M;Clyne, M;Saldova, R;McCann, A (2018) 'Resident Bacteria in Breast Cancer Tissue: Pathogenic Agents or Harmless Commensals?'. Discovery Medicine, 26 :93-102 [Details] | |
| (2018) | 'Ascending Vaginal Infection Using Bioluminescent Bacteria Evokes Intrauterine Inflammation, Preterm Birth, and Neonatal Brain Injury in Pregnant Mice' Suff N;Karda R;Antinao Diaz J;Ng J;Baruteau J;Perocheau D;Tangney M;Taylor PW;Peebles D;Buckley SMK;Waddington SN; (2018) 'Ascending Vaginal Infection Using Bioluminescent Bacteria Evokes Intrauterine Inflammation, Preterm Birth, and Neonatal Brain Injury in Pregnant Mice'. The American journal of pathology, [DOI] [Details] | |
| (2017) | 'Designer Bacteria As Intratumoural Enzyme Biofactories' Lehouritis, Panos; Hogan, Glenn; Tangney, Mark (2017) 'Designer Bacteria As Intratumoural Enzyme Biofactories'. Advanced Drug Delivery Reviews, [DOI] [Full Text] [Details] | |
| (2017) | 'Development of a click beetle luciferase reporter system for enhanced bioluminescence imaging of Listeria monocytogenes: analysis in cell culture and murine infection models' Ur Rahman S, Stanton M, Casey PG, Spagnuolo A, Bensi G, Hill C, Francis KP, Tangney M, Gahan CGM. (2017) 'Development of a click beetle luciferase reporter system for enhanced bioluminescence imaging of Listeria monocytogenes: analysis in cell culture and murine infection models'. Frontiers In Microbiology, [Full Text] [Details] | |
| (2017) | 'Intratumoural production of TNFα by bacteria mediates cancer therapy' Murphy C, Rettedal E, Lehouritis P, Devoy C, Tangney M (2017) 'Intratumoural production of TNFα by bacteria mediates cancer therapy'. Plos One, [DOI] [Details] | |
| (2017) | 'Synthetic Biology in the Driving Seat of the Bioeconomy' Flores Bueso, Y.,Tangney, M. (2017) 'Synthetic Biology in the Driving Seat of the Bioeconomy'. Trends Biotechnol, 35 (5):373-378 [DOI] [Details] | |
| (2016) | 'Activation of multiple chemotherapeutic prodrugs by the natural enzymolome of tumour-localised probiotic bacteria' Lehouritis, P. Stanton, M. McCarthy, F. O. Jeavons, M. Tangney, M. (2016) 'Activation of multiple chemotherapeutic prodrugs by the natural enzymolome of tumour-localised probiotic bacteria'. Journal of controlled release : official journal of the Controlled Release Society, 222 :9-17 [DOI] [Details] | |
| (2016) | 'The Microbiota of Breast Tissue and Its Association with Breast Cancer' Urbaniak C;Gloor GB;Brackstone M;Scott L;Tangney M;Reid G; (2016) 'The Microbiota of Breast Tissue and Its Association with Breast Cancer'. Applied and Environmental Microbiology, 82 (16) [DOI] [Details] | |
| (2015) | 'Local bacteria affect the efficacy of chemotherapeutic drugs' Panos Lehouritis, Joanne Cummins, Michael Stanton, Carola T. Murphy, Florence O. McCarthy, Gregor Reid, Camilla Urbaniak, William L. Byrne & Mark Tangney (2015) 'Local bacteria affect the efficacy of chemotherapeutic drugs'. Scientific Reports, 5 [DOI] [Details] | |
| (2015) | 'In vivo bacterial imaging without engineering; A novel probe-based strategy facilitated by endogenous nitroreductase enzymes' Stanton, M.,Cronin, M.,Lehouritis, P.,Tangney, M. (2015) 'In vivo bacterial imaging without engineering; A novel probe-based strategy facilitated by endogenous nitroreductase enzymes'. Current Gene Therapy, [Details] | |
| (2015) | 'Development of a Bioluminescent Nitroreductase Probe for Preclinical Imaging' Vorobyeva, A. G., M. Stanton, A. Godinat, K. B. Lund, G. G. Karateev, K. P. Francis, E. Allen, J. G. Gelovani, E. McCormack, M. Tangney and E. A. Dubikovskaya (2015) 'Development of a Bioluminescent Nitroreductase Probe for Preclinical Imaging'. Plos One, 10 (6) [Details] | |
| (2014) | 'Bacterial-Mediated Knockdown of Tumor Resistance to an Oncolytic Virus Enhances Therapy' Cronin, M;Le Boeuf, F;Murphy, C;Roy, DG;Falls, T;Bell, JC;Tangney, M (2014) 'Bacterial-Mediated Knockdown of Tumor Resistance to an Oncolytic Virus Enhances Therapy'. Molecular Therapy, 22 :1188-1197 [DOI] [Details] | |
| (2014) | 'Bacterial-mediated DNA delivery to tumour associated phagocytic cells' Byrne WL, Murphy CT, Cronin M, Wirth T, Tangney M (2014) 'Bacterial-mediated DNA delivery to tumour associated phagocytic cells'. Journal of controlled release : official journal of the Controlled Release Society, [DOI] [Details] | |
| (2014) | 'Microbiota of Human Breast Tissue' Urbaniak, C,Cummins, J,Brackstone, M,Macklaim, JM,Gloor, GB,Baban, CK,Scott, L,O'Hanlon, DM,Burton, JP,Francis, KP,Tangney, M,Reid, G (2014) 'Microbiota of Human Breast Tissue'. Applied and Environmental Microbiology, 80 :3007-3014 [DOI] [Details] | |
| (2014) | 'Bacterial systems for gene delivery to systemic tumors' Cummins J, Cronin M, van Pijkeren JP, Gahan CG, Tangney M (2014) 'Bacterial systems for gene delivery to systemic tumors'. Methods in molecular biology (Clifton, N.J.), 1141 :201-209 [DOI] [Details] | |
| (2014) | 'Oral Tolerance to Cancer Can Be Abrogated by T Regulatory Cell Inhibition' Whelan, MC,Casey, G,Larkin, JO,Guinn, BA,O'Sullivan, GC,Tangney, M (2014) 'Oral Tolerance to Cancer Can Be Abrogated by T Regulatory Cell Inhibition'. Plos One, 9 [DOI] [Details] | |
| (2013) | 'Use of optical imaging to progress novel therapeutics to the clinic' Byrne, WL,DeLille, A,Kuo, C,de Jong, JS,van Dam, GM,Francis, KP,Tangney, M (2013) 'Use of optical imaging to progress novel therapeutics to the clinic'. Journal of controlled release : official journal of the Controlled Release Society, 172 :523-534 [DOI] [Details] | |
| (2013) | 'New targets for the immunotherapy of colon cancer-does reactive disease hold the answer?' Boncheva, V.,Bonney, S. A.,Brooks, S. E.,Tangney, M.,O'Sullivan, G.,Mirnezami, A.,Guinn, B. A. (2013) 'New targets for the immunotherapy of colon cancer-does reactive disease hold the answer?'. Cancer Gene Ther, [Details] | |
| (2013) | 'Bacteria and tumours: causative agents or opportunistic inhabitants?' Cummins, J.,Tangney, M. (2013) 'Bacteria and tumours: causative agents or opportunistic inhabitants?'. Infectious Agents and Cancer, [Details] | |
| (2013) | 'Use of optical imaging to progress novel therapeutics to the clinic' Byrne WL, Delille A, Kuo C, de Jong JS, van Dam GM, Francis KP, Tangney M (2013) 'Use of optical imaging to progress novel therapeutics to the clinic'. Journal of controlled release : official journal of the Controlled Release Society, [DOI] [Details] | |
| (2013) | 'Bacterial-directed enzyme prodrug therapy' Lehouritis P, Springer C, Tangney M (2013) 'Bacterial-directed enzyme prodrug therapy'. Journal of controlled release : official journal of the Controlled Release Society, [DOI] [Details] | |
| (2013) | 'New targets for the immunotherapy of colon cancer-does reactive disease hold the answer?' Boncheva V, Bonney SA, Brooks SE, Tangney M, O'Sullivan G, Mirnezami A, Guinn BA (2013) 'New targets for the immunotherapy of colon cancer-does reactive disease hold the answer?'. Cancer Gene Therapy, [DOI] [Details] | |
| (2013) | 'Adenovirus-Mediated Transcriptional Targeting of Colorectal Cancer and Effects on Treatment-Resistant Hypoxic Cells' Rajendran S, O'Sullivan GC, O'Hanlon D, Tangney M (2013) 'Adenovirus-Mediated Transcriptional Targeting of Colorectal Cancer and Effects on Treatment-Resistant Hypoxic Cells'. Clinical colorectal cancer, [DOI] [Details] | |
| (2012) | 'Polymer coatings for delivery of nucleic acid therapeutics' Laga R, Carlisle R, Tangney M, Ulbrich K, Seymour LW (2012) 'Polymer coatings for delivery of nucleic acid therapeutics'. Journal of controlled release : official journal of the Controlled Release Society, [DOI] [Details] | |
| (2012) | 'In vivo Imaging & Gene Therapy' Tangney M (2012) 'In vivo Imaging & Gene Therapy'. Current Gene Therapy, [Details] | |
| (2012) | 'High resolution in vivo bioluminescent imaging for the study of bacterial tumour targeting' Cronin, M.,Akin, A. R.,Collins, S. A.,Meganck, J.,Kim, J. B.,Baban, C. K.,Joyce, S. A.,van Dam, G. M.,Zhang, N.,van Sinderen, D.,O'Sullivan, G. C.,Kasahara, N.,Gahan, C. G.,Francis, K. P.,Tangney, M. (2012) 'High resolution in vivo bioluminescent imaging for the study of bacterial tumour targeting'. Plos One, 7 (11) [Details] | |
| (2012) | 'PET Imaging For Gene & Cell Therapy' Collins, S. A.,Hiraoka, K.,Inagaki, A.,Kasahara, N.,Tangney, M. (2012) 'PET Imaging For Gene & Cell Therapy'. Curr Gene Ther, [Details] | |
| (2012) | 'In vivo Optical Imaging in Gene & Cell Therapy' Tangney, M.,Francis, K. P. (2012) 'In vivo Optical Imaging in Gene & Cell Therapy'. Curr Gene Ther, [Details] | |
| (2012) | 'Pre-treatment with Bifidobacterium breve UCC2003 modulates Citrobacter rodentium-induced colonic inflammation and organ specificity of infection' Collins, J. W.,Akin, A. R.,Kosta, A.,Zhang, N.,Tangney, M.,Francis, K. P.,Frankel, G. (2012) 'Pre-treatment with Bifidobacterium breve UCC2003 modulates Citrobacter rodentium-induced colonic inflammation and organ specificity of infection'. Microbiology, [Details] | |
| (2012) | 'Bioluminescent bacterial imaging in vivo' Baban CK, Cronin M, Akin AR, O'Brien A, Gao X, Tabirca S, Francis KP, Tangney M (2012) 'Bioluminescent bacterial imaging in vivo'. Journal of visualized experiments : JoVE, (69) [DOI] [Details] | |
| (2012) | 'DNA vaccination for prostate cancer, from preclinical to clinical trials - where we stand?' Ahmad S, Sweeney P, Sullivan GC, Tangney M (2012) 'DNA vaccination for prostate cancer, from preclinical to clinical trials - where we stand?'. Genetic vaccines and therapy, 10 (1) [DOI] [Details] | |
| (2012) | 'Bacterial Vectors for Imaging and Cancer Gene Therapy: A Review' Cronin, M.,Stanton, M.,Francis, K. P.,Tangney, M. (2012) 'Bacterial Vectors for Imaging and Cancer Gene Therapy: A Review'. Cancer Gene Ther, [Details] | |
| (2012) | 'Control and augmentation of long-term plasmid transgene expression in vivo in murine muscle tissue and ex vivo in patient mesenchymal tissue' Morrissey, D.,van Pijkeren, J.P. ,Rajendran, S.,Collins, S.,Casey, G.,O’Sullivan, G.C. ,Tangney, M. (2012) 'Control and augmentation of long-term plasmid transgene expression in vivo in murine muscle tissue and ex vivo in patient mesenchymal tissue'. J Biomed Biotechnol, [Details] | |
| (2011) | 'The emerging role of viruses in the treatment of solid tumours' Bourke, M. G.,Salwa, S.,Harrington, K. J.,Kucharczyk, M. J.,Forde, P. F.,de Kruijf, M.,Soden, D.,Tangney, M.,Collins, J. K.,O'Sullivan, G. C.; (2011) 'The emerging role of viruses in the treatment of solid tumours'. Cancer Treat Rev, [Details] | |
| (2011) | 'Targeting of Breast Metastases Using a Viral Gene Vector with Tumour-selective Transcription' Rajendran, S.,Collins, S.,V. A. N. Pijkeren JP,O'Hanlon, D.,O'Sullivan, G. C.,Tangney, M.; (2011) 'Targeting of Breast Metastases Using a Viral Gene Vector with Tumour-selective Transcription'. Anticancer Res, 31 (55):1627-351627 [Details] | |
| (2011) | 'Preclinical Evaluation Of Gene Delivery Methods For The Treatment Of Loco-Regional Disease In Breast Cancer' Rajendran, S.,O'Hanlon, D.,Morrissey, D.,O'Donovan, D.,O'Sullivan, G.C.,Tangney, M.; (2011) 'Preclinical Evaluation Of Gene Delivery Methods For The Treatment Of Loco-Regional Disease In Breast Cancer'. Exp Biol Med, 236 (4):423-434 [Details] | |
| (2011) | 'Induction of Effective Antitumor Response After Mucosal Bacterial Vector Mediated DNA Vaccination With Endogenous Prostate Cancer Specific Antigen' Ahmad, S.,Casey, G.,Cronin, M.,Rajendran, S.,Sweeney, P.,Tangney, M.,O'Sullivan, G. C.; (2011) 'Induction of Effective Antitumor Response After Mucosal Bacterial Vector Mediated DNA Vaccination With Endogenous Prostate Cancer Specific Antigen'. J Urol, [Details] | |
| (2010) | 'Gene therapy for prostate cancer' Tangney, M.,Ahmad, S.,Collins, S. A.,O'Sullivan, G. C.; (2010) 'Gene therapy for prostate cancer'. Postgrad Med, 122 (33):166-80166 [Details] | |
| (2010) | 'Gene therapy for cancer: dairy bacteria as delivery vectors' Tangney, M.; (2010) 'Gene therapy for cancer: dairy bacteria as delivery vectors'. Discov Med, 10 (5252):195-200195 [Details] | |
| (2010) | 'Ex Vivo Culture of Patient Tissue & Examination of Gene Delivery' Rajendran, S.,Salwa, S.,Gao, X.,Tabirca, S.,O'Hanlon, D.,O'Sullivan, G. C.,Tangney, M.; (2010) 'Ex Vivo Culture of Patient Tissue & Examination of Gene Delivery'. J Vis Exp, (46) [Details] | |
| (2010) | 'Murine bioluminescent hepatic tumour model' Rajendran, S.,Salwa, S.,Gao, X.,Tabirca, S.,O'Hanlon, D.,O'Sullivan, G. C.,Tangney, M.; (2010) 'Murine bioluminescent hepatic tumour model'. J Vis Exp, (4141) [Details] | |
| (2010) | 'Tumour targeting with systemically administered bacteria' Morrissey, D.,O'Sullivan, G. C.,Tangney, M.; (2010) 'Tumour targeting with systemically administered bacteria'. Curr Gene Ther, 10 (11):3-143 [Details] | |
| (2010) | 'International Society for Cell and Gene Therapy of Cancer 2009 Annual Meeting held in Cork, Ireland' Guinn, B.,Casey, G.,Moller, M. G.,Kasahara, N.,O'Sullivan, G. C.,Peng, K. W.,Tangney, M.; (2010) 'International Society for Cell and Gene Therapy of Cancer 2009 Annual Meeting held in Cork, Ireland'. Hum Gene Ther, 21 (11):9-269 [Details] | |
| (2010) | 'Orally administered bifidobacteria as vehicles for delivery of agents to systemic tumors' Cronin, M.,Morrissey, D.,Rajendran, S.,El Mashad, S. M.,van Sinderen, D.,O'Sullivan, G. C.,Tangney, M.; (2010) 'Orally administered bifidobacteria as vehicles for delivery of agents to systemic tumors'. Mol Ther, 18 (77):1397-4071397 [Details] | |
| (2010) | 'AAV2-mediated in vivo immune gene therapy of solid tumours' Collins, S. A.,Buhles, A.,Scallan, M. F.,Harrison, P. T.,O'Hanlon, D. M.,O'Sullivan, G. C.,Tangney, M.; (2010) 'AAV2-mediated in vivo immune gene therapy of solid tumours'. Genetic vaccines and therapy, 8 [Details] | |
| (2010) | 'Sonoporation mediated immunogene therapy of solid tumors' Casey, G.,Cashman, J. P.,Morrissey, D.,Whelan, M. C.,Larkin, J. O.,Soden, D. M.,Tangney, M.,O'Sullivan, G. C.; (2010) 'Sonoporation mediated immunogene therapy of solid tumors'. Ultrasound Med Biol, 36 (33):430-40430 [Details] | |
| (2010) | 'Bacteria as vectors for gene therapy of cancer' Baban, C.K. ,Cronin, M.C.,Oâ¿¿Hanlon, D.M.,Oâ¿¿Sullivan, G.C.,Tangney, M.; (2010) 'Bacteria as vectors for gene therapy of cancer'. BioEngineered Bugs, 1 (6):385-394 [Details] | |
| (2010) | 'Optimised electroporation mediated DNA vaccination for treatment of prostate cancer' Ahmad, S.,Casey, G.,Sweeney, P.,Tangney, M.,O'Sullivan, G. C.; (2010) 'Optimised electroporation mediated DNA vaccination for treatment of prostate cancer'. Genet Vaccines Ther, 8 (11) [Details] | |
| (2010) | 'Listeria monocytogenes as a vector for anti-cancer therapies' Tangney, M.,Gahan, C. G.; (2010) 'Listeria monocytogenes as a vector for anti-cancer therapies'. Curr Gene Ther, 10 (11):46-5546 [Details] | |
| (2010) | 'A novel Listeria monocytogenes-based DNA delivery system for cancer gene therapy' van Pijkeren, J. P.,Morrissey, D.,Monk, I. R.,Cronin, M.,Rajendran, S.,O'Sullivan, G. C.,Gahan, C. G.,Tangney, M.; (2010) 'A novel Listeria monocytogenes-based DNA delivery system for cancer gene therapy'. Hum Gene Ther, 21 (44):405-16405 [Details] | |
| (2010) | 'Editorial [Hot Topic: Bacterial Vectors for Gene & Cell Therapy]' Tangney, M.,Gahan, C. G.; (2010) 'Editorial [Hot Topic: Bacterial Vectors for Gene & Cell Therapy]'. Curr Gene Ther, 10 (11):1-21 [Details] | |
| (2010) | 'Effective immunotherapy of weakly immunogenic solid tumours using a combined immunogene therapy and regulatory T-cell inactivation' Whelan, M. C.,Casey, G.,MacConmara, M.,Lederer, J. A.,Soden, D.,Collins, J. K.,Tangney, M.,O'Sullivan, G. C.; (2010) 'Effective immunotherapy of weakly immunogenic solid tumours using a combined immunogene therapy and regulatory T-cell inactivation'. Cancer Gene Ther, 17 (77):501-11501 [Details] | |
| (2010) | 'The use of Listeria monocytogenes as a DNA delivery vector for cancer gene therapy' Tangney, M.,van Pijkeren, J. P.,Gahan, C. G.; (2010) 'The use of Listeria monocytogenes as a DNA delivery vector for cancer gene therapy'. Bioeng Bugs, 1 (44):284-7284 [Details] | |
| (2009) | 'Prostate stem cell antigen DNA vaccination breaks tolerance to self-antigen and inhibits prostate cancer growth' Ahmad, S.,Casey, G.,Sweeney, P.,Tangney, M.,O'Sullivan, G. C.; (2009) 'Prostate stem cell antigen DNA vaccination breaks tolerance to self-antigen and inhibits prostate cancer growth'. Mol Ther, 17 (66):1101-81101 [Details] | |
| (2009) | 'Anti-metastatic effects of viral and non-viral mediated Nk4 delivery to tumours' Buhles, A.,Collins, S. A.,van Pijkeren, J. P.,Rajendran, S.,Miles, M.,O'Sullivan, G. C.,O'Hanlon, D. M.,Tangney, M.; (2009) 'Anti-metastatic effects of viral and non-viral mediated Nk4 delivery to tumours'. Genet Vaccines Ther, 7 [Details] | |
| (2008) | 'Immune gene therapy as a neoadjuvant to surgical excision to control metastatic cancers' Cashman, J. P.,Larkin, J. O.,Casey, G.,Whelan, M. C.,Collins, C.,Aarons, S.,Tangney, M.,O'Sullivan, G. C.; (2008) 'Immune gene therapy as a neoadjuvant to surgical excision to control metastatic cancers'. Cancer Lett, 262 (11):94-10294 [Details] | |
| (2008) | 'Viral vectors in cancer immunotherapy: which vector for which strategy?' Collins, S. A.,Guinn, B. A.,Harrison, P. T.,Scallan, M. F.,O'Sullivan, G. C.,Tangney, M.; (2008) 'Viral vectors in cancer immunotherapy: which vector for which strategy?'. Curr Gene Ther, 8 (22):66-7866 [Details] | |
| (2008) | 'Tripartite meeting in gene and cell therapy, 2008: Irish Society for Gene and Cell Therapy, British Society for Gene Therapy, and International Society for Cell and Gene Therapy of Cancer' Guinn, B.,Casey, G.,Collins, S.,O'Brien, T.,Alexander, M. Y.,Tangney, M.; (2008) 'Tripartite meeting in gene and cell therapy, 2008: Irish Society for Gene and Cell Therapy, British Society for Gene Therapy, and International Society for Cell and Gene Therapy of Cancer'. Hum Gene Ther, 19 (1010):967-78967 [Details] | |
| (2008) | 'Effective tumor treatment using optimized ultrasound-mediated delivery of bleomycin' Larkin, J. O.,Casey, G. D.,Tangney, M.,Cashman, J.,Collins, C. G.,Soden, D. M.,O'Sullivan, G. C.; (2008) 'Effective tumor treatment using optimized ultrasound-mediated delivery of bleomycin'. Ultrasound Med Biol, 34 (33):406-13406 [Details] | |
| (2008) | 'Multimedia visualisation for Breast Cancer' Chen, YJ,Rajendran, S,Tangney, M,Tabirca, S; (2008) 'Multimedia visualisation for Breast Cancer'. International Journal of Computers Communications & Control, 3 :206-211 [Details] | |
| (2007) | 'Modulation of p21-activated kinase 1 alters the behavior of renal cell carcinoma' O'Sullivan, G. C.,Tangney, M.,Casey, G.,Ambrose, M.,Houston, A.,Barry, O. P.; (2007) 'Modulation of p21-activated kinase 1 alters the behavior of renal cell carcinoma'. Int J Cancer, 121 (99):1930-401930 [Details] | |
| (2007) | 'Improved luciferase tagging system for Listeria monocytogenes allows real-time monitoring in vivo and in vitro' Riedel, C. U.,Monk, I. R.,Casey, P. G.,Morrissey, D.,O'Sullivan, G. C.,Tangney, M.,Hill, C.,Gahan, C. G.; (2007) 'Improved luciferase tagging system for Listeria monocytogenes allows real-time monitoring in vivo and in vitro'. Applied and Environmental Microbiology, 73 (99):3091-43091 [Details] | |
| (2007) | 'Electrochemotherapy: aspects of preclinical development and early clinical experience' Larkin, J. O.,Collins, C. G.,Aarons, S.,Tangney, M.,Whelan, M.,O'Reily, S.,Breathnach, O.,Soden, D. M.,O'Sullivan, G. C.; (2007) 'Electrochemotherapy: aspects of preclinical development and early clinical experience'. Ann Surg, 245 (33):469-79469 [Details] | |
| (2006) | 'Oral immune tolerance mediated by suppressor T cells may be responsible for the poorer prognosis of foregut cancers' Larkin, J.,Tangney, M.,Collins, C.,Casey, G.,O'Brien, M. G.,Soden, D.,O'Sullivan, G. C.; (2006) 'Oral immune tolerance mediated by suppressor T cells may be responsible for the poorer prognosis of foregut cancers'. Med Hypotheses, 66 (33):541-4541 [Details] | |
| (2006) | 'Successful application of targeted electrochemotherapy using novel flexible electrodes and low dose bleomycin to solid tumours' Soden, D. M.,Larkin, J. O.,Collins, C. G.,Tangney, M.,Aarons, S.,Piggott, J.,Morrissey, A.,Dunne, C.,O'Sullivan, G. C.; (2006) 'Successful application of targeted electrochemotherapy using novel flexible electrodes and low dose bleomycin to solid tumours'. Cancer Lett, 232 (22):300-10300 [Details] | |
| (2006) | 'Non-viral in vivo immune gene therapy of cancer: combined strategies for treatment of systemic disease' Tangney, M.,Casey, G.,Larkin, J. O.,Collins, C. G.,Soden, D.,Cashman, J.,Whelan, M. C.,O'Sullivan, G. C.; (2006) 'Non-viral in vivo immune gene therapy of cancer: combined strategies for treatment of systemic disease'. Cancer Immunol Immunother, 55 (1111):1443-501443 [Details] | |
| (2006) | 'Local gene therapy of solid tumors with GM-CSF and B7-1 eradicates both treated and distal tumors' Tangney, M.*,Collins, C. G.*,Larkin, J. O.,Casey, G.,Whelan, M. C.,Cashman, J.,Murphy, J.,Soden, D.,Vejda, S.,McKenna, S.,Kiely, B.,Collins, J. K.,Barrett, J.,Aarons, S.,O'Sullivan, G. C.; (2006) 'Local gene therapy of solid tumors with GM-CSF and B7-1 eradicates both treated and distal tumors'. Cancer Gene Ther, 13 (1212):1061-711061 [Details] | |
| (2006) | 'Evaluation of cellular uptake and gene transfer efficiency of pegylated poly-L-lysine compacted DNA: implications for cancer gene therapy' Walsh, M.,Tangney, M.,O'Neill, M. J.,Larkin, J. O.,Soden, D. M.,McKenna, S. L.,Darcy, R.,O'Sullivan, G. C.,O'Driscoll, C. M.; (2006) 'Evaluation of cellular uptake and gene transfer efficiency of pegylated poly-L-lysine compacted DNA: implications for cancer gene therapy'. Mol Pharm, 3 (66):644-53644 [Details] | |
| (2005) | 'Combined electric field and ultrasound therapy as a novel anti-tumour treatment' Larkin, J.,Soden, D.,Collins, C.,Tangney, M.,Preston, J. M.,Russell, L. J.,McHale, A. P.,Dunne, C.,O'Sullivan, G. C.; (2005) 'Combined electric field and ultrasound therapy as a novel anti-tumour treatment'. Eur J Cancer, 41 (99):1339-481339 [Details] | |
| (2004) | 'Salmonella carriage in an Irish pig herd: correlation between serological and bacteriological detection methods' Casey, P. G.,Butler, D.,Gardiner, G. E.,Tangney, M.,Simpson, P.,Lawlor, P. G.,Stanton, C.,Ross, R. P.,Hill, C.,Fitzgerald, G. F.; (2004) 'Salmonella carriage in an Irish pig herd: correlation between serological and bacteriological detection methods'. Journal of Food Protection, 67 (1212):2797-8002797 [Details] | |
| (2004) | 'Isolation and characterization of anti-Salmonella lactic acid bacteria from the porcine gastrointestinal tract' Casey, P. G.,Casey, G. D.,Gardiner, G. E.,Tangney, M.,Stanton, C.,Ross, R. P.,Hill, C.,Fitzgerald, G. F.; (2004) 'Isolation and characterization of anti-Salmonella lactic acid bacteria from the porcine gastrointestinal tract'. Letters of Applied Microbiology, 39 (55):431-8431 [Details] | |
| (2002) | 'Effectiveness of the lactococcal abortive infection systems AbiA, AbiE, AbiF and AbiG against P335 type phages' Tangney, M.,Fitzgerald, G. F.; (2002) 'Effectiveness of the lactococcal abortive infection systems AbiA, AbiE, AbiF and AbiG against P335 type phages'. FEMS Microbiol Lett, 210 (11):67-7267 [Details] | |
| (2002) | 'AbiA, a lactococcal abortive infection mechanism functioning in Streptococcus thermophilus' Tangney, M.,Fitzgerald, G. F.; (2002) 'AbiA, a lactococcal abortive infection mechanism functioning in Streptococcus thermophilus'. Appl Environ Microbiol, 68 (1212):6388-916388 [Details] | |
| (2000) | 'Identification of a DNA region from lactococcal phage sk1 protecting phage 712 from the abortive infection mechanism AbiF' Rince, A.,Tangney, M.,Fitzgerald, G. F.; (2000) 'Identification of a DNA region from lactococcal phage sk1 protecting phage 712 from the abortive infection mechanism AbiF'. FEMS Microbiol Lett, 182 (11):185-91185 [Details] | |
| (1999) | 'Expression, regulation, and mode of action of the AbiG abortive infection system of lactococcus lactis subsp. cremoris UC653' O'Connor, L.,Tangney, M.,Fitzgerald, G. F.; (1999) 'Expression, regulation, and mode of action of the AbiG abortive infection system of lactococcus lactis subsp. cremoris UC653'. Appl Environ Microbiol, 65 (11):330-5330 [Details] |
Book Chapters
| Year | Publication | |
|---|---|---|
| (2016) | 'In Vivo Bioluminescence Imaging Of Intra-Tumoural Bacteria' Michelle Cronin, Ali Akin, Kevin Francis and Mark Tangney (2016) 'In Vivo Bioluminescence Imaging Of Intra-Tumoural Bacteria' In: Bacterial Therapy of Cancer: Methods and Protocols. New York: Springer. [DOI] [Details] | |
| (2015) | 'Bacteria as Gene Therapy Vectors for Cancer' Byrne, W. L.,Tangney, M. (2015) 'Bacteria as Gene Therapy Vectors for Cancer' In: Smyth Templeton, N (eds). Gene and Cell Therapy: Therapeutic Mechanisms and Strategies. Florida, USA: CRC Press. [Details] | |
| (2013) | 'Plasmid Transgene Expression In vivo; Promoter and Tissue Variables' Morrissey, D.,Collins, S. A.,Rajendran, S.,Casey, G.,O'Sullivan, G. C.,Tangney, M. (2013) 'Plasmid Transgene Expression In vivo; Promoter and Tissue Variables' In: Gene Therapy. Croatia: In Tech. [Details] | |
| (2011) | 'Comparison of DNA Delivery and Expression Using Frequently Used Delivery Methods' Collins SA, Morrissey D, Rajendran S, Casey G, Scallan MF, Harrison PT, O'Sullivan GC, Tangney M. ; (2011) 'Comparison of DNA Delivery and Expression Using Frequently Used Delivery Methods' In: Gene Therapy - developments and future perspectives. Croatia: InTech. [Details] |
Professional Activities
Honours and Awards
| Year | Title | Awarding Body | |
|---|---|---|---|
| 2012 | UCC Teaching Fellow | UCC | |
| 2011 | Cork Person of the Month | Cork Person of the Year Body | |
| 2010 | The Outstanding Young Person award (Junior Chamber International- Europe) | Junior Chamber International | |
| 2007 | UCC Quality Promotion Unit Award for Research on Innovative Forms of Teaching and Learning | UCC | |
| 2007 | UCC President's Strategic Fund for initiatives in the area of generic training for postgraduate students | UCC |
Professional Associations
| Association | Function | From / To | |
|---|---|---|---|
| International Society of Cell & Gene Therapy for Cancer (ISCGT) | Vice Secretary | 16-NOV-16 / | |
| Irish Association for Cancer Research (IACR) | Council member | 01-MAR-13 / | |
| Irish Society for Gene & Cell Therapy | Vice President | 10-JUN-09 / | |
| European Society for Gene & Cell Therapy (ESGCT) | Scientific Committee member (Non-Viral Vectors committee) | 01-FEB-12 / 01-FEB-15 | |
| Current Gene Therapy | Associate Editor | 06-JAN-11 / |
Education
| Year | Institution | Qualification | Subject | |
|---|---|---|---|---|
| 2001 | UCC | PHD | Molecular Biology | |
| 2014 | UCC | MBA | MBA |
Outreach Activities
| Description | |
|---|---|
Empowering all with scientific literacy: - Developing Country Initiatives: Erasmus+ funded initiatives with Latin American universities; Equipment donation to Latin American laboratories. - Schools: Development of 2nd level school modules; BT Young Scientist Competition entries; Hosting of Public Engagement events (Science & Society); Science Foundation Ireland STAR projects from 2007-2009 - General Public: Charity fundraising for research; Frequent TV, Radio and press appearances. Regular guest speaker to community groups. |
Journal Activities
| Journal | Role | To / From | |
|---|---|---|---|
| Current Gene Therapy | Editor | 01-JAN-11 - | |
| Scientific Reportsscientific Reports | Member of Editorial Board | 01-JAN-17 - | |
| Molecular Therapy | Member of Editorial Board | 01-JUL-15 - | |
| Human Gene Therapy | Member of Editorial Board | 01-JAN-09 - | |
| Bioengineered | Member of Editorial Board | 12-JUN-13 - | |
| Member of Editorial Board | 06-FEB-10 - |
Other Activities
| Description | |
|---|---|
- Regular journal reviewer for Nature Medicine; Nature Nanotechnology; PLoS One; Molecular Therapy; Cancer Gene Therapy; Oncogene; Cancer Immunology Immunotherapy; Clinical Medicine & Research; Journal of Gene Medicine; Leukemia and Lymphoma; Gene Therapy; BioEnginered; Biomarker Insights; Cancer Therapy; J. Medical Hypotheses; J. Angiogenesis; A CS Chemical Biology; Journal of Controlled Release; Integrative Biology; Human Gene Therapy; Technology in Cancer Research & Treatment; Journal of Healthcare Engineering; International Journal of Cancer; Expert Reviews in Molecular Medicine; Current Microbiology; Theranostics - Ad hoc grant reviewer for EU; Medical Research Council UK; Association for International Cancer Research; Breast Cancer Campaign UK; The French National Research Agency; Genesis Oncology Trust, New Zealand; Research Grants Council Hong Kong; Swiss National Science Foundation; Genome British Columbia |
Teaching Activities
Teaching Interests
- iEd Hub: The iEd Hub is an educational consortium featuring the Cork region’s universities, enterprise stakeholders and leading industries in the Health & Life Sciences sector. Together, the partners co-designing and deliver novel postgraduate programmes that develop the future leaders of this sector. Programmes focus on operations and management, coupled with relevant technical skills.The iEd Hub is funded by €8.7 million awarded under the Government’s Human Capital Initiative Programme (HCI), designed to meet priority skills needs across Ireland’s economy. http://iedhub.ie
- Research-led Teaching; e.g. iGEM http://2017.igem.org/Team:UCC_Ireland#
Recent Postgraduates
| Graduation Year | Student Name | Institution | Degree Type | Thesis Title | |
|---|---|---|---|---|---|
| 2020 | Venkata Vamsi Bharadwaj Yallapragada | NUI (UCC) | PHD | In silico-aided design, build and test of synthetic proteins | |
| 2020 | Sidney Walker | NUI (UCC) | PHD | Bacterial inhabitants of tumours: Methods for exploration and exploitation | |
| 2020 | Yensi Flores Bueso | NUI (UCC) | PHD | Development of methods for the microbiome analysis of formalin fixed paraffin embedded tissue specimens | |
| 2021 | Glenn Hogan | NUI (UCC) | PHD | Investigation of orally administrable bacteria for cancer therapy | |
| 2016 | Michael Stanton | University College Cork | PhD | Development of tumour imaging and therapy strategies utilising unengineered bacteria | |
| 2014 | Chwanrow Baban | NUI (UCC) | PhD | Exploring the relationship between bacteria and tumors | |
| 2014 | Simon Rajendran | NUI (UCC) | PhD | Ex vivo culture of patient tissue and examination of gene delivery | |
| 2013 | William Byrne | NUI (UCC) | PhD | Immune Gene Therapy for Cancer | |
| 2011 | Sara Collins | NUI (UCC) | PhD | AAV-mediated cancer gene therapy | |
| 2010 | David Morrissey | NUI (UCC) | PhD | Bacterial cancer therapy | |
| 2012 | Ryan Guo | NUI (UCC) | PhD | Cancer 3D Modelling | |
| 2010 | Yin Jen Chi | NUI (UCC) | PhD | Visualisation Frameworks for Tumour Growth | |
| 2009 | Sarfraz Ahmad | NUI (UCC) | PhD | DNA vaccination for prostate cancer |
Contact details
- John Mark Tangney
Professor in Education for Enterprise - Head of iEd Hub - m.tangney@ucc.ie
- CancerResearch@UCC
Western Gateway Building
University College Cork
Ireland - +353214205709