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Research Profile

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Biography

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Research Interests

Research Grants

 ProjectFunding
Body		Start DateEnd DateAward
SFI "Structural determinants of thermal sensitivity in the cold & menthol receptor TRPM8"Science Foundation of Ireland01-JUL-0631-DEC-09€153,000.00
HRB "Molecular mechanisms of cold-induced pain"Health Research Board01-OCT-0630-SEP-10€207,246.00
HRB - Structural determinants of thermal sensitivity in the cold and menthol receptor TRPM8Health Research Board08-JUN-0907-AUG-09€2,000.00
The investigation of Electrotactile, Vibro tactile and Audio/Human Machine Interfaces (HMI's) to Transmit Visual Information to the Visually Impaired.Health Research Board06-JUN-1131-JUL-11€2,000.00
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Publications

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Peer Reviewed Journals

 YearPublication
(2010)'Electrophysiological and neurochemical techniques to investigate sensory neurons in analgesia research'
Babes A, Fischer MJ, Reid G, Sauer SK, Zimmermann K, Reeh PW. (2010) 'Electrophysiological and neurochemical techniques to investigate sensory neurons in analgesia research'. Methods In Molecular Biology, 617 :237-259 [Details]
(2009)'Acute and chronic effects of neurotrophic factors BDNF and GDNF on responses mediated by thermo-sensitive TRP channels in cultured rat dorsal root ganglion neurons'
Ciobanu, C,Reid, G,Babes, A; (2009) 'Acute and chronic effects of neurotrophic factors BDNF and GDNF on responses mediated by thermo-sensitive TRP channels in cultured rat dorsal root ganglion neurons'. Brain Research, 1284 :54-67 [DOI] [Details]
(2007)'Desensitization of cold- and menthol-sensitive rat dorsal root ganglion neurones by inflammatory mediators'
Linte, Ramona Madalina and Ciobanu, Cristian and Reid, Gordon and Babes, Alexandru; (2007) 'Desensitization of cold- and menthol-sensitive rat dorsal root ganglion neurones by inflammatory mediators'. EXPERIMENTAL BRAIN RESEARCH, 178 (1):89-98 [DOI] [Details]
(2006)'A novel type of cold-sensitive neuron in rat dorsal root ganglia with rapid adaptation to cooling stimuli'
Babes, Alexandru and Zorzon, Daniel and Reid, Gordon; (2006) 'A novel type of cold-sensitive neuron in rat dorsal root ganglia with rapid adaptation to cooling stimuli'. EUROPEAN JOURNAL OF NEUROSCIENCE, 24 (3):691-698 [DOI] [Details]
(2005)'ThermoTRP channels and cold sensing: what are they really up to?'
Reid, G. (2005) 'ThermoTRP channels and cold sensing: what are they really up to?'. Pflugers Archiv-European Journal Of Physiology, 451 :250-263 [Details]
(2004)'Two populations of cold-sensitive neurons in rat dorsal root ganglia and their modulation by nerve growth factor'
Babes, A and Zorzon, D and Reid, G; (2004) 'Two populations of cold-sensitive neurons in rat dorsal root ganglia and their modulation by nerve growth factor'. EUROPEAN JOURNAL OF NEUROSCIENCE, 20 (9):2276-2282 [DOI] [Details]
(2002)'A cold- and menthol-activated current in rat dorsal root ganglion neurones: properties and role in cold transduction'
Reid, G and Babes, A and Pluteanu, F; (2002) 'A cold- and menthol-activated current in rat dorsal root ganglion neurones: properties and role in cold transduction'. JOURNAL OF PHYSIOLOGY-LONDON, 545 (2):595-614 [DOI] [Details]
(2002)'Ion channels activated by cold and menthol in cultured rat dorsal root ganglion neurones'
Reid, G and Flonta, ML; (2002) 'Ion channels activated by cold and menthol in cultured rat dorsal root ganglion neurones'. NEUROSCIENCE LETTERS, 324 (2):164-168 [Details]
(2002)'Cooling inhibits capsaicin-induced currents in cultured rat dorsal root ganglion neurones'
Babes, A and Amuzescu, B and Krause, U and Scholz, A and Flonta, ML and Reid, G; (2002) 'Cooling inhibits capsaicin-induced currents in cultured rat dorsal root ganglion neurones'. NEUROSCIENCE LETTERS, 317 (3):131-134 [Details]
(2001)'Slowed inactivation at positive potentials in a rat axonal K+ channel is not due to preferential closed-state inactivation'
Babes, A and Lorinczi, E and Ristoiu, V and Flonta, ML and Reid, G; (2001) 'Slowed inactivation at positive potentials in a rat axonal K+ channel is not due to preferential closed-state inactivation'. PHYSIOLOGICAL RESEARCH, 50 (6):557-565 [Details]
(2001)'A system for applying rapid warming or cooling stimuli to cells during patch clamp recording or ion imaging'
Reid, G and Amuzescu, B and Zech, E and Flonta, ML; (2001) 'A system for applying rapid warming or cooling stimuli to cells during patch clamp recording or ion imaging'. JOURNAL OF NEUROSCIENCE METHODS, 111 (1):1-8 [Details]
(2001)'Cold transduction by inhibition of a background potassium conductance in rat primary sensory neurones'
Reid, G and Flonta, ML; (2001) 'Cold transduction by inhibition of a background potassium conductance in rat primary sensory neurones'. NEUROSCIENCE LETTERS, 297 (3):171-174 [Details]
(2001)'Physiology - Cold current in thermoreceptive neurons'
Reid, G and Flonta, ML; (2001) 'Physiology - Cold current in thermoreceptive neurons'. NATURE, 413 (6855) [Details]
(1999)'A functional role of the erg-like inward-rectifying K+ current in prolactin secretion from rat lactotrophs'
Bauer, CK and Schafer, R and Schiemann, D and Reid, G and Hanganu, I and Schwarz, JR; (1999) 'A functional role of the erg-like inward-rectifying K+ current in prolactin secretion from rat lactotrophs'. MOLECULAR AND CELLULAR ENDOCRINOLOGY, 148 (1-2):37-45 [Details]
(1999)'Human axons contain at least five types of voltage-dependent potassium channel'
Reid, G and Scholz, A and Bostock, H and Vogel, W; (1999) 'Human axons contain at least five types of voltage-dependent potassium channel'. JOURNAL OF PHYSIOLOGY-LONDON, 518 (3):681-696 [Details]
(1996)'Most lactotrophs from lactating rats are able to respond to both thyrotropin-releasing hormone and dopamine'
Reid, G and Bauer, CK and Bunting, R and Mason, WT and Schwarz, JR; (1996) 'Most lactotrophs from lactating rats are able to respond to both thyrotropin-releasing hormone and dopamine'. MOLECULAR AND CELLULAR ENDOCRINOLOGY, 124 (1-2):121-129 [Details]
(1995)'ACTION-POTENTIALS AND MEMBRANE CURRENTS IN THE HUMAN NODE OF RANVIER'
SCHWARZ, JR and REID, G and BOSTOCK, H; (1995) 'ACTION-POTENTIALS AND MEMBRANE CURRENTS IN THE HUMAN NODE OF RANVIER'. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 430 (2):283-292 [Details]
(1995)'Axonal ion channel dysfunction in amyotrophic lateral sclerosis'
Bostock, H., Sharief, M.K., Reid, G., Murray, N.M.F (1995) 'Axonal ion channel dysfunction in amyotrophic lateral sclerosis'. Brain, 118 :217-225 [Details]
(1995)'The effects of vasoactive intestinal polypeptide and substance P on methacholine-induced sweating and vascular flare in diabetic neuropathy'
Berg, T.J., Levy, D.M., Reid, G., Abraham, R.R. (1995) 'The effects of vasoactive intestinal polypeptide and substance P on methacholine-induced sweating and vascular flare in diabetic neuropathy'. Clinical Autonomic Research, 5 :159-164 [Details]
(1994)'Activating effect of the flavonoid phloretin on Ca2+-activated K+ channels in myelinated nerve fibres of Xenopus laevis'
Koh, D.-S., Reid G., Vogel, W. (1994) 'Activating effect of the flavonoid phloretin on Ca2+-activated K+ channels in myelinated nerve fibres of Xenopus laevis'. Neuroscience Letters, 165 :167-170 [Details]
(1993)'Ion channels in human axons'
Scholz, A., Reid, G., Vogel, W., Bostock, H. (1993) 'Ion channels in human axons'. Journal of Neurophysiology, 70 :1274-1279 [Details]
(1992)'Quantitative measures of sympathetic skin response in diabetes: relation to sudomotor and neurological function'
Levy, D.M., Reid, G., Rowley, D.A., Abraham, R.R. (1992) 'Quantitative measures of sympathetic skin response in diabetes: relation to sudomotor and neurological function'. Journal of Neurology, Neurosurgery and Psychiatry, 55 :902-908 [Details]
(1991)'CHANGES IN EXCITABILITY AND ACCOMMODATION OF HUMAN MOTOR AXONS FOLLOWING BRIEF PERIODS OF ISCHEMIA'
BOSTOCK, H and BAKER, M and GRAFE, P and REID, G; (1991) 'CHANGES IN EXCITABILITY AND ACCOMMODATION OF HUMAN MOTOR AXONS FOLLOWING BRIEF PERIODS OF ISCHEMIA'. JOURNAL OF PHYSIOLOGY-LONDON, 441 :513-535 [Details]
(1991)'CHANGES IN EXCITABILITY OF HUMAN MOTOR AXONS UNDERLYING POSTISCHEMIC FASCICULATIONS - EVIDENCE FOR 2 STABLE STATES'
BOSTOCK, H and BAKER, M and REID, G; (1991) 'CHANGES IN EXCITABILITY OF HUMAN MOTOR AXONS UNDERLYING POSTISCHEMIC FASCICULATIONS - EVIDENCE FOR 2 STABLE STATES'. JOURNAL OF PHYSIOLOGY-LONDON, 441 :537-557 [Details]
(1991)'Assessment of basal and stimulated sweating in diabetes using a direct-reading computerised sudorometer'
Levy, D.M., Reid, G., Abraham, R.R., Rowley, D.A. (1991) 'Assessment of basal and stimulated sweating in diabetes using a direct-reading computerised sudorometer'. Diabetic Medicine, 8 :78S-81S [Details]
(1989)'A COMPARISON OF 2 METHODS FOR MEASURING THERMAL THRESHOLDS IN DIABETIC NEUROPATHY'
LEVY, D and ABRAHAM, R and REID, G; (1989) 'A COMPARISON OF 2 METHODS FOR MEASURING THERMAL THRESHOLDS IN DIABETIC NEUROPATHY'. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 52 (9):1072-1077 [Details]
(2013)'Camphor Activates and Sensitizes Transient Receptor Potential Melastatin 8 (TRPM8) to Cooling and Icilin'
Selescu, T,Ciobanu, AC,Dobre, C,Reid, G,Babes, A (2013) 'Camphor Activates and Sensitizes Transient Receptor Potential Melastatin 8 (TRPM8) to Cooling and Icilin'. Chemical Senses, 38 :563-575 [DOI] [Details]
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Book Chapters

 YearPublication
(2004)'Excitability of human nerve: basic mechanisms and effects of hyperglycaemia, hypoxia and ischaemia'
Reid. G.; (2004) 'Excitability of human nerve: basic mechanisms and effects of hyperglycaemia, hypoxia and ischaemia' In: Vascular Involvement in Diabetes: Clinical and Experimental Data. Romanian Academy: Romanian Academy. [Details]
(2002)'Properties and localisation of ionic channels in myelinated and unmyelinated nerve fibres'
Scholz, A., Reid, G. ; (2002) 'Properties and localisation of ionic channels in myelinated and unmyelinated nerve fibres' In: Ion Channels and Physiopathologies of Nerve Conduction and Cell Proliferation. Research Signpost Publications: Research Signpost Publications. [Details]
(1996)'Ion channels in human axons'
Reid, G. ; (1996) 'Ion channels in human axons' In: Neurobiology of Disease - Contributions from Neuroscience to Clinical Neurology. Cambridge: Cambridge University Press. [Details]
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Conference Publications

 YearPublication
(2008)Proc Physiol Soc 11 PC114
Doran C & Reid G. ; (2008) Direct modulatory effect of inflammatory mediators on cold- and menthol-sensitive neurons from rat dorsal root ganglia¿ Proc Physiol Soc 11 PC114 [Details]
(2005)J. Physiol. 567P:D12
Reid, G., Zorzon, D. ; (2005) A rapid system for applying thermal stimuli during patch clamp and [Ca2+]i imaging experiments J. Physiol. 567P:D12 [Details]
(2005)J. Physiol. 567P:PC74
Linte, R., Babes, A., Reid, G. ; (2005) The increase in cold sensitivity in rat dorsal root ganglion (DRG) neurones induced by nerve growth factor (NGF) is mediated by the high affinity NGF receptor J. Physiol. 567P:PC74 [Details]
(2005)J. Physiol. 567P:C42
Reid, G.; (2005) Innocuous warm transduction in chick primary sensory neurones depends on TRPV3 J. Physiol. 567P:C42 [Details]
(2005)J. Physiol. 567P:C43
Babes, A., Zorzon, D., Reid, G. ; (2005) A novel type of cold-sensitive neurone in rat dorsal root ganglia (DRG) with rapid adaptation to cooling J. Physiol. 567P:C43 [Details]
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Abstract

 YearPublication
(2011)THE EFFECTS OF VARIATIONS IN THE N-TERMINUS ON THE SENSITIVITY OF CHICK TRPM8 TO MENTHOL AND COLD.
Morshed, N,Reid, G (2011) THE EFFECTS OF VARIATIONS IN THE N-TERMINUS ON THE SENSITIVITY OF CHICK TRPM8 TO MENTHOL AND COLD. Abstract [Details]
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Professional Activities

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Honours and Awards

 YearTitleAwarding Body
2003Niculae Simionescu Prize (for most outstanding piece of research in the biological sciences in Romania) Romanian Academy
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Conference Contributions

 YearPublication
(2005)Presentation to Physiological Society meeting, Bristol,
G.Reid; (2005) Innocuous warm transduction in chick primary sensory neurones depends on TRPV3. [Oral Presentation], Presentation to Physiological Society meeting, Bristol, Bristol , 01-JAN-05 - 01-JAN-05. [Details]
(2006)Invited talk, ¿Mechanisms Underlying Emerging Themes in Neurobiology¿ meeting, Cork,
G.Reid; (2006) Mechanisms of cold transduction and cold-induced pain. [Oral Presentation], Invited talk, ¿Mechanisms Underlying Emerging Themes in Neurobiology¿ meeting, Cork, Cork , 01-JAN-06 - 01-JAN-06. [Details]
(2007)Invited talk, Royal Academy of Medicine in Ireland, Cork,
G.Reid; (2007) Transduction of painful cold. [Oral Presentation], Invited talk, Royal Academy of Medicine in Ireland, Cork, Cork , 01-JAN-07 - 01-JAN-07. [Details]
(2008)Invited talk, Physiological Society meeting, Cambridge,
G.Reid; (2008) Transduction of painful cold: an open question?. [Oral Presentation], Invited talk, Physiological Society meeting, Cambridge, Cambridge , 01-JAN-08 - 01-JAN-08. [Details]
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Committees

 CommitteeFunctionFrom / To
Mechanisms of sensory transduction in the skin Dublin (Physiological Society meeting) Symposium co-organiser/
Royal Academy of Medicine in Ireland meeting Cork Member of local organising committee/
Long, strange TRPs: properties and functions of TRPM and related channels Glasgow, Scotland (Physiological Society meeting) Symposium co-organiser/
Membrane mechanisms of cold sensing Prague, Czech Republic (IBRO meeting) Symposium co-organiser/
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Employment

 EmployerPositionFrom / To
Institute of Neurology, London Research assistant/
University of Hamburg, Germany Research associate/
University of Bucharest, Romania Professor/
Department/Research Centre Physiology College Lecturer/
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Education

 YearInstitutionQualificationSubject
1997University College, London PHDphysiology
1984University of Glasgow BSCPhysiology
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Languages

 LanguageReadingWritingSpeaking
Ulster-Scots FluentFluentFluent
Romanian FluentBasicFluent
German FluentFluentFluent
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Outreach Activities

 Description

2010: Scientific advisor to "Bang Goes the Theory" (BBC television, UK)
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Journal Activities

 JournalRoleTo / From
Neuroscience Letters Referee-
Experimental Brain Research Referee-
Experimental Cell Research Referee-
Journal Of Cellular And Molecular Medicine Referee-
Investigative Ophthamology And Visual Science Referee-
Cell Calcium Referee-
Molecular Pain Referee-
European Journal Of Neuroscience Referee-
Journal Of Neurophysiology Referee-
Journal Of Physiology Referee-
Nature Referee-
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Other Activities

 Description

List of Expert Assignments:

Abstract and poster reviewing Physiological Society meetings (several) 2001-2008
PhD examining (internal examiner, 2 candidates) University of Bucharest, Romania 2002
Investigated and reported on claim by Prof. Gheorghe Benga for a share of 2003 Nobel Prize in Chemistry, for Romanian Government Bucharest, Romania 2003
Drafted guidelines for Biology Commission of CNCSIS, the Romanian national research council, on criteria for awarding research grants in cell & molecular biology Bucharest, Romania 2005
 


Scholarly Activities

2007-2008

Sponsor of a Physiological Society Junior Fellow, Cristian Ciobanu (PhD student, Bucharest, Romania); this sponsorship involved framing a programme of joint research to be carried out by Mr. Ciobanu in Bucharest and also in my lab in Cork during research visits. 


Research Talks:

Potassium channels in human axons Pfizer UK, Sandwich Kent, UK 1990
Mechanisms of excitability in human axons University of Hamburg, Germany 1991
Ion channels in human axons University of Bucharest, Romania 1997
Cold-activated currents in thermoreceptive neurones Institute of Biochemistry, Bucharest, Romania 2002
Potassium channels in cold transduction Simionescu Institute, Bucharest, Romania 2002
Mechanisms of cold transduction: TRP channels Glaxo Smith Kline, Harlow, Essex, UK 2002
Mechanisms of cold transduction and cold pain University of Bristol, UK 2002
Mechanisms of cold transduction and cold pain University of Aberdeen, UK 2003
Mechanisms of cold transduction and cold pain University of Glasgow, UK 2003
Transduction of painful cold - an open question IBRO summer school, Bucharest, Romania 2004
Transduction of painful cold - an open question? PENS summer school, Bucharest, Romania 2007
Construction of chimeric ion channels Wellcome Trust/Physiological Society Molecular Techniques Workshop, Cork 2007
 


Visits Abroad:

University of Giessen, Germany (Prof. W. Vogel) Collaborative research Several visits, Nov 1989-Sept 1992, total 2 months
University of Hamburg, Germany (Prof. J.R. Schwarz) Collaborative research 3 visits, Jan-April 1993, total 3 weeks
AFRC Institute of Animal Physiology, Babraham, Cambridge, UK (Prof. W.T. Mason) Collaborative research 1 week, July 1995
University of Bucharest, Romania (Prof. M.L. Flonta) Teaching research methods, guiding the construction of a patch clamp setup 2 weeks, May 1997
University College, London (Prof. H. Bostock) Collaborative research, collection of literature 3 weeks, July 1998
University of Giessen, Germany (Dr. A. Scholz) Collaborative research Feb 2000, 2 weeks
University of Marburg, Germany (Dr. H.A. Braun) Collaborative research June 2000, 2 weeks
University of Bristol (Dept. of Physiology and Prof. Sally Lawson) Visiting professorship, collaborative research Nov 2002 - Feb 2003, June-Aug 2003 (total 3 months)
Prague, Czech Republic Symposium organisation and presentation June 2003, 5 days
Göttingen, Germany Invited talk June 2003, 2 days
London, UK Physiological Society meeting July 2003, 4 days
Verona, Italy Invited talk September 2003, 5 days
Glasgow, UK Symposium organisation and presentation April 2004, 5 days
Bristol, UK Physiological Society meeting July 2005, 4 days
Glasgow, UK Physiological Society meeting July 2007, 4 days
Cambridge, UK Physiological Society meeting, invited talk July 2008, 4 days
Glasgow & Edinburgh, UK World Pain Congress and satellite symposium August 2008, 5 days
 

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Teaching Activities

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Teaching Interests

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Modules Taught

 Term (ID))TitleLinkSubject
2015Fundamentals of Physiology PL1025Fundamentals of Physiology
2015Neurophysiology PL3020Neurophysiology
2015Basic Science for Dental Hygiene PL1011Basic Science for Dental Hygiene

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