Fergus Shanahan

Director
Alimentary Pharmabotic Centre (Apc)
BioSciences Building
University College Cork

T: +353 21 490 1226
E: f.shanahan@ucc.ie
Professor
Medicine Department
University College Cork
Ireland

T: 353-21-490-1226
F: 353-21-434 5300
E: f.shanahan@ucc.ie

Fergus Shanahan is Professor and Chairman of the Department of Medicine at University College Cork (UCC), National University of Ireland.  Born and educated in Dublin, he attended medical school at University College Dublin where he graduated with honours in 1977.  After internship and residency in internal medicine in Dublin, he did a two-year fellowship in clinical immunology at McMaster University in Ontario, Canada, followed by a two-year fellowship in gastroenterology at the University of California, Los Angeles (UCLA).  After completion of his fellowship at UCLA, he was appointed to the faculty there, rising to the rank of Associate Professor before making the decision, in 1993, to return to his native Ireland. 

Together with colleagues from several departments and different faculties within University College Cork and Teagasc (a research agency of the Irish Ministry of Food and Agriculture), Dr. Shanahan led a team of clinicians, clinician-scientists, and basic scientists to successfully compete for seed funding from Science Foundation Ireland to create a multi-disciplinary research center, the Alimentary Pharmabiotic Centre, which investigates host-microbe interactions in the gut in health and disease.  Under Dr. Shanahan’s directorship, the center now has a membership of 168 staff, scientists, and students and has expanded its funding and research base by securing research alliances with indigenous and multinational companies within the food and pharmaceutical sectors. 

Dr. Shanahan has published more than 450 scientific papers and several on the medical humanities and has co-edited several books.  He is a Fellow of the Royal College of Physicians in Ireland, Canada, and the United Kingdom as well as of the American College of Physicians.  He served as President of the Irish Society of Gastroenterology from 2007-2009.  He was recently named to the “Irish Life Science 50” a list of the top 50 Irish and Irish Americans in the life science industry. In 2013, Science Foundation Ireland named him as its Researcher of the Year.  

His interests are in mucosal immunology, gut microbiota, inflammatory bowel disease, and most things that affect the human experience.

PUBLICATIONS: for an accurate list, please log onto PubMed and enter Shanahan F (orhttp://www.ncbi.nlm.nih.gov/pubmed/?term=Shanahan+F)

Research Interests

Gastrointestinal immunology Host-bacterial interactions within the gut

Peer Reviewed Journals

YearPublication
(2014)'Cognitive performance in irritable bowel syndrome: evidence of a stress-related impairment in visuospatial memory'
Kennedy, P. J.,Clarke, G.,O'Neill, A.,Groeger, J. A.,Quigley, E. M.,Shanahan, F.,Cryan, J. F.,Dinan, T. G. (2014) 'Cognitive performance in irritable bowel syndrome: evidence of a stress-related impairment in visuospatial memory'. Psychol Med, 44 (77):1553-66 Globe icon [Details]
(2014)'A Functional Approach Reveals a Genetic and Physical Interaction between Ribonucleotide Reductase and CHK1 in Mammalian Cells'
Taricani, L.,Shanahan, F.,Malinao, M. C.,Beaumont, M.,Parry, D. (2014) 'A Functional Approach Reveals a Genetic and Physical Interaction between Ribonucleotide Reductase and CHK1 in Mammalian Cells'. PLoS One, 9 (1111) [Details]
(2014)'Selective influence of host microbiota on cAMP-mediated ion transport in mouse colon'
Lomasney, K. W.,Houston, A.,Shanahan, F.,Dinan, T. G.,Cryan, J. F.,Hyland, N. P. (2014) 'Selective influence of host microbiota on cAMP-mediated ion transport in mouse colon'. Neurogastroenterol Motil, 26 (66):887-90 Globe icon [Details]
(2014)'The utilisation and diagnostic yield of radiological imaging in a specialist functional GI disorder clinic: an 11-year retrospective study'
Breen, M.,Murphy, K. P.,O'Neill, S. B.,O'Donovan, J. P.,McWilliams, S.,Desmond, A. N.,Shanahan, F.,Quigley, E. M.,Maher, M. M. (2014) 'The utilisation and diagnostic yield of radiological imaging in a specialist functional GI disorder clinic: an 11-year retrospective study'. Eur Radiol, 24 (1212):3097-104 [Details]
(2014)'Exercise and associated dietary extremes impact on gut microbial diversity'
Clarke, S. F.,Murphy, E. F.,O'Sullivan, O.,Lucey, A. J.,Humphreys, M.,Hogan, A.,Hayes, P.,O'Reilly, M.,Jeffery, I. B.,Wood-Martin, R.,Kerins, D. M.,Quigley, E.,Ross, R. P.,O'Toole, P. W.,Molloy, M. G.,Falvey, E.,Shanahan, F.,Cotter, P. D. (2014) 'Exercise and associated dietary extremes impact on gut microbial diversity'. Gut, 63 (1212):1913-20 [Details]
(2014)'Detection of Mycobacterium avium subspecies paratuberculosis in patients with Crohn's disease is unrelated to the presence of single nucleotide polymorphisms rs2241880 (ATG16L1) and rs10045431 (IL12B)'
Dalton, J. P.,Desmond, A.,Shanahan, F.,Hill, C. (2014) 'Detection of Mycobacterium avium subspecies paratuberculosis in patients with Crohn's disease is unrelated to the presence of single nucleotide polymorphisms rs2241880 (ATG16L1) and rs10045431 (IL12B)'. Med Microbiol Immunol, 203 (33):195-205 [Details]
(2014)'Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut'
Joyce, S. A.,MacSharry, J.,Casey, P. G.,Kinsella, M.,Murphy, E. F.,Shanahan, F.,Hill, C.,Gahan, C. G. (2014) 'Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut'. Proc Natl Acad Sci U S A, 111 (2020):7421-6 [Details]
(2014)'The identification of novel 5'-amino gemcitabine analogs as potent RRM1 inhibitors'
Labroli, M. A.,Dwyer, M. P.,Shen, R.,Popovici-Muller, J.,Pu, Q.,Wyss, D.,McCoy, M.,Barrett, D.,Davis, N.,Seghezzi, W.,Shanahan, F.,Taricani, L.,Beaumont, M.,Malinao, M. C.,Parry, D.,Guzi, T. J. (2014) 'The identification of novel 5'-amino gemcitabine analogs as potent RRM1 inhibitors'. Bioorg Med Chem, 22 (77):2303-10 [Details]
(2014)'Probiotics in obese pregnancy do not reduce maternal fasting glucose: a double-blind, placebo-controlled, randomized trial (Probiotics in Pregnancy Study)'
Lindsay, K. L.,Kennelly, M.,Culliton, M.,Smith, T.,Maguire, O. C.,Shanahan, F.,Brennan, L.,McAuliffe, F. M. (2014) 'Probiotics in obese pregnancy do not reduce maternal fasting glucose: a double-blind, placebo-controlled, randomized trial (Probiotics in Pregnancy Study)'. Am J Clin Nutr, 99 (66):1432-1439 [Details]
(2014)'Exopolysaccharide-Producing Probiotic Lactobacilli Reduce Serum Cholesterol and Modify Enteric Microbiota in ApoE-Deficient Mice'
London, L. E.,Kumar, A. H.,Wall, R.,Casey, P. G.,O'Sullivan, O.,Shanahan, F.,Hill, C.,Cotter, P. D.,Fitzgerald, G. F.,Ross, R. P.,Caplice, N. M.,Stanton, C. (2014) 'Exopolysaccharide-Producing Probiotic Lactobacilli Reduce Serum Cholesterol and Modify Enteric Microbiota in ApoE-Deficient Mice'. J Nutr, 144 (1212):1956-62 [Details]
(2014)'Concomitant exposure to ovalbumin and endotoxin augments airway inflammation but not airway hyperresponsiveness in a murine model of asthma'
Mac Sharry, J.,Shalaby, K. H.,Marchica, C.,Farahnak, S.,Chieh-Li, T.,Lapthorne, S.,Qureshi, S. T.,Shanahan, F.,Martin, J. G. (2014) 'Concomitant exposure to ovalbumin and endotoxin augments airway inflammation but not airway hyperresponsiveness in a murine model of asthma'. PLoS One, 9 (66) [Details]
(2014)'Editorial: probiotics and IBS - where are we now?'
Moran, C.,Shanahan, F. (2014) 'Editorial: probiotics and IBS - where are we now?'. Aliment Pharmacol Ther, 40 (33) [Details]
(2014)'Gut microbiota and obesity: role in aetiology and potential therapeutic target'
Moran, C. P.,Shanahan, F. (2014) 'Gut microbiota and obesity: role in aetiology and potential therapeutic target'. Best Pract Res Clin Gastroenterol, 28 (44):585-97 [Details]
(2014)'The role of pure iterative reconstruction in conventional dose CT enterography'
Murphy, K. P.,Crush, L.,McLaughlin, P. D.,O'Sullivan, H. S.,Twomey, M.,Lynch, S.,Bye, J.,McSweeney, S. E.,O'Connor, O. J.,Shanahan, F.,Maher, M. M. (2014) 'The role of pure iterative reconstruction in conventional dose CT enterography'. Abdom Imaging, [Details]
(2014)'Identification of a unique hybrid macrophage-polarization state following recovery from lipopolysaccharide tolerance'
O'Carroll, C.,Fagan, A.,Shanahan, F.,Carmody, R. J. (2014) 'Identification of a unique hybrid macrophage-polarization state following recovery from lipopolysaccharide tolerance'. J Immunol, 192 (11):427-36 [Details]
(2014)'Effect of phylloquinone (vitamin K1) supplementation for 12 months on the indices of vitamin K status and bone health in adult patients with Crohn's disease'
O'Connor, E. M.,Grealy, G.,McCarthy, J.,Desmond, A.,Craig, O.,Shanahan, F.,Cashman, K. D. (2014) 'Effect of phylloquinone (vitamin K1) supplementation for 12 months on the indices of vitamin K status and bone health in adult patients with Crohn's disease'. Br J Nutr, 112 (77):1163-74 [Details]
(2014)'Ethereal and material gain: unanticipated opportunity with illness or disability'
O'Mahony, S.,Shanahan, F. (2014) 'Ethereal and material gain: unanticipated opportunity with illness or disability'. Clin Med, 14 (11):44-6 [Details]
(2014)'Disturbance of the gut microbiota in early-life selectively affects visceral pain in adulthood without impacting cognitive or anxiety-related behaviors in male rats'
O'Mahony, S. M.,Felice, V. D.,Nally, K.,Savignac, H. M.,Claesson, M. J.,Scully, P.,Woznicki, J.,Hyland, N. P.,Shanahan, F.,Quigley, E. M.,Marchesi, J. R.,O'Toole, P. W.,Dinan, T. G.,Cryan, J. F. (2014) 'Disturbance of the gut microbiota in early-life selectively affects visceral pain in adulthood without impacting cognitive or anxiety-related behaviors in male rats'. Neuroscience, 277 :885-901 [Details]
(2014)'The future of probiotics for disorders of the brain-gut axis'
Quigley, E. M.,Shanahan, F. (2014) 'The future of probiotics for disorders of the brain-gut axis'. Adv Exp Med Biol, 817 :417-32 [Details]
(2014)'Bioavailability of the anti-clostridial bacteriocin thuricin CD in gastrointestinal tract'
Rea, M. C.,Alemayehu, D.,Casey, P. G.,O'Connor, P. M.,Lawlor, P. G.,Walsh, M.,Shanahan, F.,Kiely, B.,Ross, R. P.,Hill, C. (2014) 'Bioavailability of the anti-clostridial bacteriocin thuricin CD in gastrointestinal tract'. Microbiology, 160 (Pt 2Pt 2):439-45 [Details]
(2014)'The sustained trajectory of small bowel research'
Shanahan, F. (2014) 'The sustained trajectory of small bowel research'. Curr Opin Gastroenterol, 30 (22):117-9 [Details]
(2014)'Author response: linking lifestyle and microbes'
Shanahan, F.,Clarke, S. F.,Murphy, E. F.,O'Sullivan, O.,Cotter, P. (2014) 'Author response: linking lifestyle and microbes'. Gut, [Details]
(2014)'Host-microbe interactions and spatial variation of cancer in the gut'
Shanahan, F.,O'Toole, P. W. (2014) 'Host-microbe interactions and spatial variation of cancer in the gut'. Nat Rev Cancer, 14 (88):511-2 [Details]
(2014)'Manipulation of the microbiota for treatment of IBS and IBD-challenges and controversies'
Shanahan, F.,Quigley, E. M. (2014) 'Manipulation of the microbiota for treatment of IBS and IBD-challenges and controversies'. Gastroenterology, 146 (66):1554-63 [Details]
(2014)'Gastric digestion of alpha-lactalbumin in adult human subjects using capsule endoscopy and nasogastric tube sampling'
Sullivan, L. M.,Kehoe, J. J.,Barry, L.,Buckley, M. J.,Shanahan, F.,Mok, K. H.,Brodkorb, A. (2014) 'Gastric digestion of alpha-lactalbumin in adult human subjects using capsule endoscopy and nasogastric tube sampling'. Br J Nutr, 112 (44):638-46 [Details]
(2014)'Microbiota is essential for social development in the mouse'
Desbonnet, L.,Clarke, G.,Shanahan, F.,Dinan, T. G.,Cryan, J. F. (2014) 'Microbiota is essential for social development in the mouse'. Mol Psychiatry, 19 (22):146-8 Globe icon [Details]
(2013)'A prospective feasibility study of sub-millisievert abdominopelvic CT using iterative reconstruction in Crohn's disease'
O'Neill, S. B.,Mc Laughlin, P. D.,Crush, L.,O'Connor, O. J.,Mc Williams, S. R.,Craig, O.,Mc Garrigle, A. M.,O'Neill, F.,Bye, J.,Ryan, M. F.,Shanahan, F.,Maher, M. M. (2013) 'A prospective feasibility study of sub-millisievert abdominopelvic CT using iterative reconstruction in Crohn's disease'. Eur Radiol, 23 (99):2503-25122503 Globe icon [Details]
(2013)'Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis'
Yang, S.,Wang, B.,Humphries, F.,Jackson, R.,Healy, M. E.,Bergin, R.,Aviello, G.,Hall, B.,McNamara, D.,Darby, T.,Quinlan, A.,Shanahan, F.,Melgar, S.,Fallon, P. G.,Moynagh, P. N. (2013) 'Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis'. Nat Immunol, 14 (99):927-36 [Details]
(2013)'Targeting the EP1 receptor reduces Fas ligand expression and increases the antitumor immune response in an in vivo model of colon cancer'
O'Callaghan, G.,Ryan, A.,Neary, P.,O'Mahony, C.,Shanahan, F.,Houston, A. (2013) 'Targeting the EP1 receptor reduces Fas ligand expression and increases the antitumor immune response in an in vivo model of colon cancer'. 133 (44):825-834825 Globe icon [Details]
(2013)'The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner'
Clarke, G.,Grenham, S.,Scully, P.,Fitzgerald, P.,Moloney, R. D.,Shanahan, F.,Dinan, T. G.,Cryan, J. F. (2013) 'The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner'. Mol Psychiatry, 18 (66):666-673666 Globe icon [Details]
(2013)'Gene silencing of TNF-alpha in a murine model of acute colitis using a modified cyclodextrin delivery system'
McCarthy, J.,O'Neill, M. J.,Bourre, L.,Walsh, D.,Quinlan, A.,Hurley, G.,Ogier, J.,Shanahan, F.,Melgar, S.,Darcy, R.,O'Driscoll, C. M. (2013) 'Gene silencing of TNF-alpha in a murine model of acute colitis using a modified cyclodextrin delivery system'. 168 (11):28-3428 Globe icon [Details]
(2013)'The colonic microbiota in health and disease'
Shanahan, F. (2013) 'The colonic microbiota in health and disease'. Curr Opin Gastroenterol, 29 (11):49-5449 Globe icon [Details]
(2013)'Targeting the microbiota to address diet-induced obesity: a time dependent challenge'
Clarke, S. F.,Murphy, E. F.,O'Sullivan, O.,Ross, R. P.,O'Toole, P. W.,Shanahan, F.,Cotter, P. D. (2013) 'Targeting the microbiota to address diet-induced obesity: a time dependent challenge'. PLoS One, 8 (66) [Details]
(2013)'Challenges and implications for biomedical research and intervention studies in older populations: insights from the ELDERMET study'
Cusack, S.,O'Toole, P. W. (2013) 'Challenges and implications for biomedical research and intervention studies in older populations: insights from the ELDERMET study'. Gerontology, 59 (22):114-21 [Details]
(2013)'Risk factors for hand injury in hurling: a cross-sectional study'
Falvey, E.,McCrory, P.,Crowley, B.,Kelleher, A.,Eustace, J.,Shanahan, F.,Molloy, M. G. (2013) 'Risk factors for hand injury in hurling: a cross-sectional study'. BMJ Open, 3 (55) [Details]
(2013)'Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut'
Groeger, D.,O'Mahony, L.,Murphy, E. F.,Bourke, J. F.,Dinan, T. G.,Kiely, B.,Shanahan, F.,Quigley, E. M. (2013) 'Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut'. Gut Microbes, 4 (44):325-39 [Details]
(2013)'Natural killer cells protect against mucosal and systemic infection with the enteric pathogen Citrobacter rodentium'
Hall, L. J.,Murphy, C. T.,Hurley, G.,Quinlan, A.,Shanahan, F.,Nally, K.,Melgar, S. (2013) 'Natural killer cells protect against mucosal and systemic infection with the enteric pathogen Citrobacter rodentium'. Infect Immun, 81 (22):460-9 [Details]
(2013)'TL1A/TNFSF15 directly induces proinflammatory cytokines, including TNFalpha, from CD3+CD161+ T cells to exacerbate gut inflammation'
Jin, S.,Chin, J.,Seeber, S.,Niewoehner, J.,Weiser, B.,Beaucamp, N.,Woods, J.,Murphy, C.,Fanning, A.,Shanahan, F.,Nally, K.,Kajekar, R.,Salas, A.,Planell, N.,Lozano, J.,Panes, J.,Parmar, H.,DeMartino, J.,Narula, S.,Thomas-Karyat, D. A. (2013) 'TL1A/TNFSF15 directly induces proinflammatory cytokines, including TNFalpha, from CD3+CD161+ T cells to exacerbate gut inflammation'. Mucosal Immunol, 6 (55):886-99 [Details]
(2013)'Prevalence and characterization of Clostridium perfringens from the faecal microbiota of elderly Irish subjects'
Lakshminarayanan, B.,Harris, H. M.,Coakley, M.,O'Sullivan, O.,Stanton, C.,Pruteanu, M.,Shanahan, F.,O'Toole, P. W.,Ross, R. P. (2013) 'Prevalence and characterization of Clostridium perfringens from the faecal microbiota of elderly Irish subjects'. J Med Microbiol, 62 (Pt 3Pt 3):457-66 [Details]
(2013)'Depth-dependent differences in community structure of the human colonic microbiota in health'
Lavelle, A.,Lennon, G.,Docherty, N.,Balfe, A.,Mulcahy, H. E.,Doherty, G.,O. Donoghue D,Hyland, J. M.,Shanahan, F.,Sheahan, K.,Coffey, J. C.,Winter, D. C.,O. Connell PR (2013) 'Depth-dependent differences in community structure of the human colonic microbiota in health'. PLoS One, 8 (1111) [Details]
(2013)'Movers and shakers: influence of bacteriophages in shaping the mammalian gut microbiota'
Mills, S.,Shanahan, F.,Stanton, C.,Hill, C.,Coffey, A.,Ross, R. P. (2013) 'Movers and shakers: influence of bacteriophages in shaping the mammalian gut microbiota'. Gut Microbes, 4 (11):4-16 [Details]
(2013)'Antimicrobials: Strategies for targeting obesity and metabolic health?'
Murphy, E. F.,Clarke, S. F.,Marques, T. M.,Hill, C.,Stanton, C.,Ross, R. P.,O'Doherty, R. M.,Shanahan, F.,Cotter, P. D. (2013) 'Antimicrobials: Strategies for targeting obesity and metabolic health?'. Gut Microbes, 4 (11):48-53 [Details]
(2013)'Divergent metabolic outcomes arising from targeted manipulation of the gut microbiota in diet-induced obesity'
Murphy, E. F.,Cotter, P. D.,Hogan, A.,O'Sullivan, O.,Joyce, A.,Fouhy, F.,Clarke, S. F.,Marques, T. M.,O'Toole, P. W.,Stanton, C.,Quigley, E. M.,Daly, C.,Ross, P. R.,O'Doherty, R. M.,Shanahan, F. (2013) 'Divergent metabolic outcomes arising from targeted manipulation of the gut microbiota in diet-induced obesity'. Gut, 62 (22):220-6 [Details]
(2013)'Bcl-3 deficiency protects against dextran-sodium sulphate-induced colitis in the mouse'
O'Carroll, C.,Moloney, G.,Hurley, G.,Melgar, S.,Brint, E.,Nally, K.,Nibbs, R. J.,Shanahan, F.,Carmody, R. J. (2013) 'Bcl-3 deficiency protects against dextran-sodium sulphate-induced colitis in the mouse'. Clin Exp Immunol, 173 (22):332-42 [Details]
(2013)'Digestion of epithelial tight junction proteins by the commensal Clostridium perfringens'
Pruteanu, M.,Shanahan, F. (2013) 'Digestion of epithelial tight junction proteins by the commensal Clostridium perfringens'. Am J Physiol Gastrointest Liver Physiol, 305 (1010) [Details]
(2013)'Phylogenetic analysis of dysbiosis in ulcerative colitis during remission'
Rajilic-Stojanovic, M.,Shanahan, F.,Guarner, F.,de Vos, W. M. (2013) 'Phylogenetic analysis of dysbiosis in ulcerative colitis during remission'. Inflamm Bowel Dis, 19 (33):481-8 [Details]
(2013)'Identification of TLR10 as a key mediator of the inflammatory response to Listeria monocytogenes in intestinal epithelial cells and macrophages'
Regan, T.,Nally, K.,Carmody, R.,Houston, A.,Shanahan, F.,Macsharry, J.,Brint, E. (2013) 'Identification of TLR10 as a key mediator of the inflammatory response to Listeria monocytogenes in intestinal epithelial cells and macrophages'. J Immunol, 191 (1212):6084-92 [Details]
(2013)'Bifidobacterium infantis suppression of Peyer's patch MIP-1alpha and MIP-1beta secretion during Salmonella infection correlates with increased local CD4+CD25+ T cell numbers'
Scully, P.,Macsharry, J.,O'Mahony, D.,Lyons, A.,O'Brien, F.,Murphy, S.,Shanahan, F.,O'Mahony, L. (2013) 'Bifidobacterium infantis suppression of Peyer's patch MIP-1alpha and MIP-1beta secretion during Salmonella infection correlates with increased local CD4+CD25+ T cell numbers'. Cell Immunol, 281 (22):134-40 [Details]
(2013)'The neglected spectrum of diverticular-related disorders'
Shanahan, F. (2013) 'The neglected spectrum of diverticular-related disorders'. Clin Gastroenterol Hepatol, 11 (1212):1620-1 [Details]
(2013)'In praise of the literary eponym--Henry V sign'
Shanahan, F.,Houlihan, C.,Marks, J. C. (2013) 'In praise of the literary eponym--Henry V sign'. Qjm, 106 (11):93-4 [Details]
(2013)'A randomized controlled study of mesalamine after acute diverticulitis: results of the DIVA trial'
Stollman, N.,Magowan, S.,Shanahan, F.,Quigley, E. M. (2013) 'A randomized controlled study of mesalamine after acute diverticulitis: results of the DIVA trial'. J Clin Gastroenterol, 47 (77):621-9 [Details]
(2013)'Natural killer cells protect mice from DSS-induced colitis by regulating neutrophil function via the NKG2A receptor'
Hall, L. J.,Murphy, C. T.,Quinlan, A.,Hurley, G.,Shanahan, F.,Nally, K.,Melgar, S. (2013) 'Natural killer cells protect mice from DSS-induced colitis by regulating neutrophil function via the NKG2A receptor'. Mucosal Immunol, 6 (55):1016-10261016 Globe icon [Details]
(2012)'Bifidobacterial surface-exopolysaccharide facilitates commensal-host interaction through immune modulation and pathogen protection'
Fanning, S.,Hall, L. J.,Cronin, M.,Zomer, A.,MacSharry, J.,Goulding, D.,Motherway, M. O.,Shanahan, F.,Nally, K.,Dougan, G.,van Sinderen, D. (2012) 'Bifidobacterial surface-exopolysaccharide facilitates commensal-host interaction through immune modulation and pathogen protection'. Proc Natl Acad Sci U S A, 109 (66):2108-132108 Globe icon [Details]
(2012)'Contrasting effects of Bifidobacterium breve NCIMB 702258 and Bifidobacterium breve DPC 6330 on the composition of murine brain fatty acids and gut microbiota'
Wall, R.,Marques, T. M.,O'Sullivan, O.,Ross, R. P.,Shanahan, F.,Quigley, E. M.,Dinan, T. G.,Kiely, B.,Fitzgerald, G. F.,Cotter, P. D.,Fouhy, F.,Stanton, C. (2012) 'Contrasting effects of Bifidobacterium breve NCIMB 702258 and Bifidobacterium breve DPC 6330 on the composition of murine brain fatty acids and gut microbiota'. Am J Clin Nutr, 95 (55):1278-87 [Details]
(2012)'Microbes and metabolic health'
Shanahan, F. (2012) 'Microbes and metabolic health'. Gut, 61 (1212):1655-16561655 Globe icon [Details]
(2012)'The gut microbiota-a clinical perspective on lessons learned'
Shanahan, F. (2012) 'The gut microbiota-a clinical perspective on lessons learned'. Nature Reviews Gastroenterology & Hepatology, 9 (1010):609-614609 Globe icon [Details]
(2012)'Categorization of the gut microbiota: enterotypes or gradients?'
Jeffery, I. B.,Claesson, M. J.,O'Toole, P. W.,Shanahan, F. (2012) 'Categorization of the gut microbiota: enterotypes or gradients?'. Nature Reviews. Microbiology, 10 (99):591-592591 Globe icon [Details]
(2012)'Immunomodulatory effects of feeding with Bifidobacterium longum on allergen-induced lung inflammation in the mouse'
MacSharry, J.,O'Mahony, C.,Shalaby, K. H.,Sheil, B.,Karmouty-Quintana, H.,Shanahan, F.,Martin, J. G. (2012) 'Immunomodulatory effects of feeding with Bifidobacterium longum on allergen-induced lung inflammation in the mouse'. Pulm Pharmacol Ther, 25 (44):325-334325 Globe icon [Details]
(2012)'The microbiota in inflammatory bowel disease: friend, bystander, and sometime-villain'
Shanahan, F. (2012) 'The microbiota in inflammatory bowel disease: friend, bystander, and sometime-villain'. Nutr Rev, 70 Globe icon [Details]
(2012)'Managing chronic disease in Ireland: hospital admission rates and clinical outcomes in a large ulcerative colitis population'
Desmond, A. N.,Shanahan, F. (2012) 'Managing chronic disease in Ireland: hospital admission rates and clinical outcomes in a large ulcerative colitis population'. Ir J Med Sci, 181 (11):65-7165 Globe icon [Details]
(2012)'Bacteriophages phiMR299-2 and phiNH-4 can eliminate Pseudomonas aeruginosa in the murine lung and on cystic fibrosis lung airway cells'
Alemayehu, D.,Casey, P. G.,McAuliffe, O.,Guinane, C. M.,Martin, J. G.,Shanahan, F.,Coffey, A.,Ross, R. P.,Hill, C. (2012) 'Bacteriophages phiMR299-2 and phiNH-4 can eliminate Pseudomonas aeruginosa in the murine lung and on cystic fibrosis lung airway cells'. MBio, 3 (22) [Details]
(2012)'Bifidobacterium breve with alpha-linolenic acid and linoleic acid alters fatty acid metabolism in the maternal separation model of irritable bowel syndrome'
Barrett, E.,Fitzgerald, P.,Dinan, T. G.,Cryan, J. F.,Ross, R. P.,Quigley, E. M.,Shanahan, F.,Kiely, B.,Fitzgerald, G. F.,O'Toole, P. W.,Stanton, C. (2012) 'Bifidobacterium breve with alpha-linolenic acid and linoleic acid alters fatty acid metabolism in the maternal separation model of irritable bowel syndrome'. PLoS One, 7 (1111) [Details]
(2012)'Gut microbiota composition correlates with diet and health in the elderly'
Claesson, M. J.,Jeffery, I. B.,Conde, S.,Power, S. E.,O'Connor, E. M.,Cusack, S.,Harris, H. M.,Coakley, M.,Lakshminarayanan, B.,O'Sullivan, O.,Fitzgerald, G. F.,Deane, J.,O'Connor, M.,Harnedy, N.,O'Connor, K.,O'Mahony, D.,van Sinderen, D.,Wallace, M.,Brennan, L.,Stanton, C.,Marchesi, J. R.,Fitzgerald, A. P.,Shanahan, F.,Hill, C.,Ross, R. P.,O'Toole, P. W. (2012) 'Gut microbiota composition correlates with diet and health in the elderly'. Nature, 488 (74107410):178-84 [Details]
(2012)'The gut microbiota and its relationship to diet and obesity: new insights'
Clarke, S. F.,Murphy, E. F.,Nilaweera, K.,Ross, P. R.,Shanahan, F.,O'Toole, P. W.,Cotter, P. D. (2012) 'The gut microbiota and its relationship to diet and obesity: new insights'. Gut Microbes, 3 (33):186-202 [Details]
(2012)'Carriage of Clostridium difficile in outpatients with irritable bowel syndrome'
Clayton, E. M.,Rea, M. C.,Shanahan, F.,Quigley, E. M.,Kiely, B.,Ross, R. P.,Hill, C. (2012) 'Carriage of Clostridium difficile in outpatients with irritable bowel syndrome'. J Med Microbiol, 61 (Pt 9Pt 9):1290-4 [Details]
(2012)'Diagnostic accuracy of computed tomography using lower doses of radiation for patients with Crohn's disease'
Craig, O.,O'Neill, S.,O'Neill, F.,McLaughlin, P.,McGarrigle, A.,McWilliams, S.,O'Connor, O.,Desmond, A.,Walsh, E. K.,Ryan, M.,Maher, M.,Shanahan, F. (2012) 'Diagnostic accuracy of computed tomography using lower doses of radiation for patients with Crohn's disease'. Clin Gastroenterol Hepatol, 10 (88):886-92 [Details]
(2012)'Radiation exposure from diagnostic imaging among patients with gastrointestinal disorders'
Desmond, A. N.,McWilliams, S.,Maher, M. M.,Shanahan, F.,Quigley, E. M. (2012) 'Radiation exposure from diagnostic imaging among patients with gastrointestinal disorders'. Clin Gastroenterol Hepatol, 10 (33):259-65 [Details]
(2012)'Selection of symptomatic patients with Crohn's disease for abdominopelvic computed tomography: role of serum C-reactive protein'
Desmond, A. N.,O'Regan, K.,Malik, N.,McWilliams, S.,O'Neill, S.,Quigley, E. M.,Shanahan, F.,Maher, M. M. (2012) 'Selection of symptomatic patients with Crohn's disease for abdominopelvic computed tomography: role of serum C-reactive protein'. Can Assoc Radiol J, 63 (44):267-74 [Details]
(2012)'World Gastroenterology Organisation Global Guidelines: probiotics and prebiotics October 2011'
Guarner, F.,Khan, A. G.,Garisch, J.,Eliakim, R.,Gangl, A.,Thomson, A.,Krabshuis, J.,Lemair, T.,Kaufmann, P.,de Paula, J. A.,Fedorak, R.,Shanahan, F.,Sanders, M. E.,Szajewska, H.,Ramakrishna, B. S.,Karakan, T.,Kim, N. (2012) 'World Gastroenterology Organisation Global Guidelines: probiotics and prebiotics October 2011'. J Clin Gastroenterol, 46 (66):468-81 [Details]
(2012)'Increased risk of miscarriage and ectopic pregnancy among women with irritable bowel syndrome'
Khashan, A. S.,Quigley, E. M.,McNamee, R.,McCarthy, F. P.,Shanahan, F.,Kenny, L. C. (2012) 'Increased risk of miscarriage and ectopic pregnancy among women with irritable bowel syndrome'. Clin Gastroenterol Hepatol, 10 (88):902-9 [Details]
(2012)'Portrait of an immunoregulatory Bifidobacterium'
Konieczna, P.,Akdis, C. A.,Quigley, E. M.,Shanahan, F.,O'Mahony, L. (2012) 'Portrait of an immunoregulatory Bifidobacterium'. Gut Microbes, 3 (33):261-6 [Details]
(2012)'Bifidobacterium infantis 35624 administration induces Foxp3 T regulatory cells in human peripheral blood: potential role for myeloid and plasmacytoid dendritic cells'
Konieczna, P.,Groeger, D.,Ziegler, M.,Frei, R.,Ferstl, R.,Shanahan, F.,Quigley, E. M.,Kiely, B.,Akdis, C. A.,O'Mahony, L. (2012) 'Bifidobacterium infantis 35624 administration induces Foxp3 T regulatory cells in human peripheral blood: potential role for myeloid and plasmacytoid dendritic cells'. Gut, 61 (33):354-66 [Details]
(2012)'Differential intestinal M-cell gene expression response to gut commensals'
Lapthorne, S.,Macsharry, J.,Scully, P.,Nally, K.,Shanahan, F. (2012) 'Differential intestinal M-cell gene expression response to gut commensals'. Immunology, 136 (33):312-24 [Details]
(2012)'Minimization of Radiation Exposure due to Computed Tomography in Inflammatory Bowel Disease'
Mc Laughlin, P. D.,O'Connor, O. J.,O'Neill, S. B.,Shanahan, F.,Maher, M. M. (2012) 'Minimization of Radiation Exposure due to Computed Tomography in Inflammatory Bowel Disease'. ISRN Gastroenterol, 2012 [Details]
(2012)'Computed tomography assessment of intestinal gas volumes in functional gastrointestinal disorders'
Mc Williams, S. R.,Mc Laughlin, P. D.,O'Connor, O. J.,Desmond, A. N.,Ni Laoire, A.,Shanahan, F.,Quigley, E. M.,Maher, M. M. (2012) 'Computed tomography assessment of intestinal gas volumes in functional gastrointestinal disorders'. J Neurogastroenterol Motil, 18 (44):419-25 [Details]
(2012)'CT-based estimation of intracavitary gas volumes using threshold-based segmentation: in vitro study to determine the optimal threshold range'
McWilliams, S. R.,O'Connor, O. J.,McGarrigle, A. M.,O'Neill, S. B.,Quigley, E. M.,Shanahan, F.,Maher, M. M. (2012) 'CT-based estimation of intracavitary gas volumes using threshold-based segmentation: in vitro study to determine the optimal threshold range'. J Med Imaging Radiat Oncol, 56 (33):289-94 [Details]
(2012)'The sphingosine-1-phosphate analogue FTY720 impairs mucosal immunity and clearance of the enteric pathogen Citrobacter rodentium'
Murphy, C. T.,Hall, L. J.,Hurley, G.,Quinlan, A.,MacSharry, J.,Shanahan, F.,Nally, K.,Melgar, S. (2012) 'The sphingosine-1-phosphate analogue FTY720 impairs mucosal immunity and clearance of the enteric pathogen Citrobacter rodentium'. Infect Immun, 80 (88):2712-23 [Details]
(2012)'Shining a light on intestinal traffic'
Murphy, C. T.,Nally, K.,Shanahan, F.,Melgar, S. (2012) 'Shining a light on intestinal traffic'. Clin Dev Immunol, 2012 [Details]
(2012)'Radiologic imaging in cystic fibrosis: cumulative effective dose and changing trends over 2 decades'
O'Connell, O. J.,McWilliams, S.,McGarrigle, A.,O'Connor, O. J.,Shanahan, F.,Mullane, D.,Eustace, J.,Maher, M. M.,Plant, B. J. (2012) 'Radiologic imaging in cystic fibrosis: cumulative effective dose and changing trends over 2 decades'. Chest, 141 (66):1575-83 [Details]
(2012)'Role of radiologic imaging in irritable bowel syndrome: evidence-based review'
O'Connor, O. J.,McSweeney, S. E.,McWilliams, S.,O'Neill, S.,Shanahan, F.,Quigley, E. M.,Maher, M. M. (2012) 'Role of radiologic imaging in irritable bowel syndrome: evidence-based review'. Radiology, 262 (22):485-94 [Details]
(2012)'Plain abdominal radiographs in patients with Crohn's disease: radiological findings and diagnostic value'
O'Regan, K.,O'Connor, O. J.,O'Neill, S. B.,Mc Laughlin, P. D.,Desmond, A.,McWilliams, S. R.,Quigley, E. M.,Shanahan, F.,Maher, M. M. (2012) 'Plain abdominal radiographs in patients with Crohn's disease: radiological findings and diagnostic value'. Clin Radiol, 67 (88):774-81 [Details]
(2012)'Clostridium difficile carriage in elderly subjects and associated changes in the intestinal microbiota'
Rea, M. C.,O'Sullivan, O.,Shanahan, F.,O'Toole, P. W.,Stanton, C.,Ross, R. P.,Hill, C. (2012) 'Clostridium difficile carriage in elderly subjects and associated changes in the intestinal microbiota'. J Clin Microbiol, 50 (33):867-75 [Details]
(2012)'A commentary on the safety of probiotics'
Shanahan, F. (2012) 'A commentary on the safety of probiotics'. Gastroenterol Clin North Am, 41 (44):869-76 [Details]
(2012)'The colonic microbiota and colonic disease'
Shanahan, F. (2012) 'The colonic microbiota and colonic disease'. Curr Gastroenterol Rep, 14 (55):446-52 [Details]
(2012)'Darwinian dyspepsia: an extraordinary scientist, an ordinary illness, great dignity'
Shanahan, F. (2012) 'Darwinian dyspepsia: an extraordinary scientist, an ordinary illness, great dignity'. Am J Gastroenterol, 107 (22):161-4 [Details]
(2012)'The gut microbiota in 2011: Translating the microbiota to medicine'
Shanahan, F. (2012) 'The gut microbiota in 2011: Translating the microbiota to medicine'. Nat Rev Gastroenterol Hepatol, 9 (22):72-4 [Details]
(2012)'Probiotics in transition'
Shanahan, F.,Dinan, T. G.,Ross, P.,Hill, C. (2012) 'Probiotics in transition'. Clin Gastroenterol Hepatol, 10 (1111):1220-4 [Details]
(2012)'In search of lost opportunities: Marcel Proyce and James Joust discuss doctors, diseases, life and death (a hypothetical conversation between Marcel Proust and James Joyce)'
Shanahan, F.,Quigley, E. M. (2012) 'In search of lost opportunities: Marcel Proyce and James Joust discuss doctors, diseases, life and death (a hypothetical conversation between Marcel Proust and James Joyce)'. Perspect Biol Med, 55 (11):155-61 [Details]
(2012)'Bifidobacterium infantis 35624 protects against salmonella-induced reductions in digestive enzyme activity in mice by attenuation of the host inflammatory response'
Symonds, E. L.,O'Mahony, C.,Lapthorne, S.,O'Mahony, D.,Sharry, J. M.,O'Mahony, L.,Shanahan, F. (2012) 'Bifidobacterium infantis 35624 protects against salmonella-induced reductions in digestive enzyme activity in mice by attenuation of the host inflammatory response'. Clin Transl Gastroenterol, 3 [Details]
(2012)'Mechanism of protection of transepithelial barrier function by Lactobacillus salivarius: strain dependence and attenuation by bacteriocin production'
Miyauchi, E.,O'Callaghan, J.,Butto, L. F.,Hurley, G.,Melgar, S.,Tanabe, S.,Shanahan, F.,Nally, K.,O'Toole, P. W. (2012) 'Mechanism of protection of transepithelial barrier function by Lactobacillus salivarius: strain dependence and attenuation by bacteriocin production'. American Journal of Physiology-Gastrointestinal and Liver Physiology, 303 (99) Globe icon [Details]
(2011)'Who needs doctors? Staying fresh in changing times'
Shanahan, F. (2011) 'Who needs doctors? Staying fresh in changing times'. Clin Med, 11 (66):587-588587 Globe icon [Details]
(2011)'Increased health burden associated with Clostridium difficile diarrhoea in inflammatory bowel disease'
Rampton, D. S.,Shanahan, F. (2011) 'Increased health burden associated with Clostridium difficile diarrhoea in inflammatory bowel disease'. Aliment Pharmacol Ther, 34 (33):394-395394 Globe icon [Details]
(2011)'The hybrid science of diet, microbes, and metabolic health'
Shanahan, F.,Murphy, E. (2011) 'The hybrid science of diet, microbes, and metabolic health'. 94 (11):1-21 Globe icon [Details]
(2011)'Biochemical and metabolomic phenotyping in the identification of a vitamin D responsive metabotype for markers of the metabolic syndrome'
O'Sullivan, A.,Gibney, M. J.,Connor, A. O.,Mion, B.,Kaluskar, S.,Cashman, K. D.,Flynn, A.,Shanahan, F.,Brennan, L. (2011) 'Biochemical and metabolomic phenotyping in the identification of a vitamin D responsive metabotype for markers of the metabolic syndrome'. Mol Nutr Food Res, 55 (55):679-690679 Globe icon [Details]
(2011)'Composition, variability, and temporal stability of the intestinal microbiota of the elderly'
Claesson, M. J.,Cusack, S.,O'Sullivan, O.,Greene-Diniz, R.,de Weerd, H.,Flannery, E.,Marchesi, J. R.,Falush, D.,Dinan, T.,Fitzgerald, G.,Stanton, C.,van Sinderen, D.,O'Connor, M.,Harnedy, N.,O'Connor, K.,Henry, C.,O'Mahony, D.,Fitzgerald, A. P.,Shanahan, F.,Twomey, C.,Hill, C.,Ross, R. P.,O'Toole, P. W. (2011) 'Composition, variability, and temporal stability of the intestinal microbiota of the elderly'. Proc Natl Acad Sci U S A, 108 :4586-45914586 Globe icon [Details]
(2011)'Effect of broad- and narrow-spectrum antimicrobials on Clostridium difficile and microbial diversity in a model of the distal colon'
Rea, M. C.,Dobson, A.,O'Sullivan, O.,Crispie, F.,Fouhy, F.,Cotter, P. D.,Shanahan, F.,Kiely, B.,Hill, C.,Ross, R. P. (2011) 'Effect of broad- and narrow-spectrum antimicrobials on Clostridium difficile and microbial diversity in a model of the distal colon'. Proc Natl Acad Sci U S A, 108 :4639-46444639 Globe icon [Details]
(2011)'Minimization of radiation exposure due to computed tomography in inflammatory bowel disease'
O'Neill, S. B.,O'Connor, O. J.,McWilliams, S. R.,Shanahan, F.,Maher, M. M. (2011) 'Minimization of radiation exposure due to computed tomography in inflammatory bowel disease'. Clin Res Hepatol Gastroenterol, 35 (22):105-110105 Globe icon [Details]
(2011)'An unusual phenotype in Muckle-Wells syndrome associated with NLRP3 E311K'
Murphy, G.,Daly, M.,O'Sullivan, M.,Stack, J.,Rowczenio, D.,Lachmann, H.,Shanahan, F.,Harney, S.,Hawkins, P.,Molloy, M. (2011) 'An unusual phenotype in Muckle-Wells syndrome associated with NLRP3 E311K'. Rheumatology (Oxford), 50 (22):419-420419 Globe icon [Details]
(2011)'The colonic microflora and probiotic therapy in health and disease'
Shanahan, F. (2011) 'The colonic microflora and probiotic therapy in health and disease'. Curr Opin Gastroenterol, 27 (11):61-6561 Globe icon [Details]
(2011)'Differential expression of toll-like receptors in patients with irritable bowel syndrome'
Brint, E. K.,MacSharry, J.,Fanning, A.,Shanahan, F.,Quigley, E. M. (2011) 'Differential expression of toll-like receptors in patients with irritable bowel syndrome'. Am J Gastroenterol, 106 (22):329-36 [Details]
(2011)'Perplexing plain abdominal x-ray. Radiographic opacities were due to the lanthanum'
Crush, L.,O'Connor, O. J.,Plant, W.,Clarkson, M. R.,Shanahan, F.,Maher, M. M. (2011) 'Perplexing plain abdominal x-ray. Radiographic opacities were due to the lanthanum'. Gut, 60 (22) [Details]
(2011)'Targeting the replication checkpoint using SCH 900776, a potent and functionally selective CHK1 inhibitor identified via high content screening'
Guzi, T. J.,Paruch, K.,Dwyer, M. P.,Labroli, M.,Shanahan, F.,Davis, N.,Taricani, L.,Wiswell, D.,Seghezzi, W.,Penaflor, E.,Bhagwat, B.,Wang, W.,Gu, D.,Hsieh, Y.,Lee, S.,Liu, M.,Parry, D. (2011) 'Targeting the replication checkpoint using SCH 900776, a potent and functionally selective CHK1 inhibitor identified via high content screening'. Mol Cancer Ther, 10 (44):591-602 [Details]
(2011)'Induction and activation of adaptive immune populations during acute and chronic phases of a murine model of experimental colitis'
Hall, L. J.,Faivre, E.,Quinlan, A.,Shanahan, F.,Nally, K.,Melgar, S. (2011) 'Induction and activation of adaptive immune populations during acute and chronic phases of a murine model of experimental colitis'. Dig Dis Sci, 56 (11):79-89 [Details]
(2011)'Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor'
O'Connell Motherway, M.,Zomer, A.,Leahy, S. C.,Reunanen, J.,Bottacini, F.,Claesson, M. J.,O'Brien, F.,Flynn, K.,Casey, P. G.,Munoz, J. A.,Kearney, B.,Houston, A. M.,O'Mahony, C.,Higgins, D. G.,Shanahan, F.,Palva, A.,de Vos, W. M.,Fitzgerald, G. F.,Ventura, M.,O'Toole, P. W.,van Sinderen, D. (2011) 'Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor'. Proc Natl Acad Sci U S A, 108 (2727):11217-22 [Details]
(2011)'Degradation of the extracellular matrix components by bacterial-derived metalloproteases: implications for inflammatory bowel diseases'
Pruteanu, M.,Hyland, N. P.,Clarke, D. J.,Kiely, B.,Shanahan, F. (2011) 'Degradation of the extracellular matrix components by bacterial-derived metalloproteases: implications for inflammatory bowel diseases'. Inflamm Bowel Dis, 17 (55):1189-200 [Details]
(2011)'Recombinant lactobacilli expressing linoleic acid isomerase can modulate the fatty acid composition of host adipose tissue in mice'
Rosberg-Cody, E.,Stanton, C.,O'Mahony, L.,Wall, R.,Shanahan, F.,Quigley, E. M.,Fitzgerald, G. F.,Ross, R. P. (2011) 'Recombinant lactobacilli expressing linoleic acid isomerase can modulate the fatty acid composition of host adipose tissue in mice'. Microbiology, 157 (Pt 2Pt 2):609-15 [Details]
(2011)'Small intestinal bacterial overgrowth in nonalcoholic steatohepatitis: association with toll-like receptor 4 expression and plasma levels of interleukin 8'
Shanab, A. A.,Scully, P.,Crosbie, O.,Buckley, M.,O'Mahony, L.,Shanahan, F.,Gazareen, S.,Murphy, E.,Quigley, E. M. (2011) 'Small intestinal bacterial overgrowth in nonalcoholic steatohepatitis: association with toll-like receptor 4 expression and plasma levels of interleukin 8'. Dig Dis Sci, 56 (55):1524-34 [Details]
(2011)'Molecular mechanisms of probiotic action: it's all in the strains!'
Shanahan, F. (2011) 'Molecular mechanisms of probiotic action: it's all in the strains!'. Gut, 60 (88):1026-7 [Details]
(2011)'Enterococcus faecalis metalloprotease compromises epithelial barrier and contributes to intestinal inflammation'
Steck, N.,Hoffmann, M.,Sava, I. G.,Kim, S. C.,Hahne, H.,Tonkonogy, S. L.,Mair, K.,Krueger, D.,Pruteanu, M.,Shanahan, F.,Vogelmann, R.,Schemann, M.,Kuster, B.,Sartor, R. B.,Haller, D. (2011) 'Enterococcus faecalis metalloprotease compromises epithelial barrier and contributes to intestinal inflammation'. Gastroenterology, 141 (33):959-71 [Details]
(2010)'Mycobacterium avium subsp. Paratuberculosis (MAP) as a modifying factor in Crohn's disease'
Sibartie, S.,Scully, P.,Keohane, J.,O'Neill, S.,O'Mahony, J.,O'Hanlon, D.,Kirwan, W. O.,O'Mahony, L.,Shanahan, F. (2010) 'Mycobacterium avium subsp. Paratuberculosis (MAP) as a modifying factor in Crohn's disease'. Inflamm Bowel Dis, 16 (22):296-304 [Details]
(2010)'Exercise-induced bronchoconstriction and exercise testing in an international rugby union team'
Falvey, E. C.,McCarthy, C.,O'Connor, T. M.,Shanahan, F.,Molloy, M. G.,Plant, B. J. (2010) 'Exercise-induced bronchoconstriction and exercise testing in an international rugby union team'. Thorax, 65 (99):843-844843 Globe icon [Details]
(2010)'Esophageal intramural pseudodiverticulosis characterized by barium esophagography: a case report'
O'Connor, O. J.,Brady, A.,Shanahan, F.,Quigley, E.,O'Riordain, M.,Maher, M. M. (2010) 'Esophageal intramural pseudodiverticulosis characterized by barium esophagography: a case report'. J Med Case Rep, 4 [Details]
(2010)'Bifidobacterium animalis AHC7 protects against pathogen-induced NF-kappaB activation in vivo'
O'Mahony, D.,Murphy, S.,Boileau, T.,Park, J.,O'Brien, F.,Groeger, D.,Konieczna, P.,Ziegler, M.,Scully, P.,Shanahan, F.,Kiely, B.,O'Mahony, L. (2010) 'Bifidobacterium animalis AHC7 protects against pathogen-induced NF-kappaB activation in vivo'. BMC Immunol, 11 [Details]
(2010)'Dinaciclib (SCH 727965), a novel and potent cyclin-dependent kinase inhibitor'
Parry, D.,Guzi, T.,Shanahan, F.,Davis, N.,Prabhavalkar, D.,Wiswell, D.,Seghezzi, W.,Paruch, K.,Dwyer, M. P.,Doll, R.,Nomeir, A.,Windsor, W.,Fischmann, T.,Wang, Y.,Oft, M.,Chen, T.,Kirschmeier, P.,Lees, E. M. (2010) 'Dinaciclib (SCH 727965), a novel and potent cyclin-dependent kinase inhibitor'. Mol Cancer Ther, 9 (88):2344-53 [Details]
(2010)'Discovery of Dinaciclib (SCH 727965): A Potent and Selective Inhibitor of Cyclin-Dependent Kinases'
Paruch, K.,Dwyer, M. P.,Alvarez, C.,Brown, C.,Chan, T. Y.,Doll, R. J.,Keertikar, K.,Knutson, C.,McKittrick, B.,Rivera, J.,Rossman, R.,Tucker, G.,Fischmann, T.,Hruza, A.,Madison, V.,Nomeir, A. A.,Wang, Y.,Kirschmeier, P.,Lees, E.,Parry, D.,Sgambellone, N.,Seghezzi, W.,Schultz, L.,Shanahan, F.,Wiswell, D.,Xu, X.,Zhou, Q.,James, R. A.,Paradkar, V. M.,Park, H.,Rokosz, L. R.,Stauffer, T. M.,Guzi, T. J. (2010) 'Discovery of Dinaciclib (SCH 727965): A Potent and Selective Inhibitor of Cyclin-Dependent Kinases'. ACS Med Chem Lett, 1 (55):204-8 [Details]
(2010)'Asymptomatic carriage of Clostridium difficile in an Irish continuing care institution for the elderly: prevalence and characteristics'
Ryan, J.,Murphy, C.,Twomey, C.,Paul Ross, R.,Rea, M. C.,MacSharry, J.,Sheil, B.,Shanahan, F. (2010) 'Asymptomatic carriage of Clostridium difficile in an Irish continuing care institution for the elderly: prevalence and characteristics'. Ir J Med Sci, 179 (22):245-50 [Details]
(2010)'Plasma cytokine profiles in females with irritable bowel syndrome and extra-intestinal co-morbidity'
Scully, P.,McKernan, D. P.,Keohane, J.,Groeger, D.,Shanahan, F.,Dinan, T. G.,Quigley, E. M. (2010) 'Plasma cytokine profiles in females with irritable bowel syndrome and extra-intestinal co-morbidity'. Am J Gastroenterol, 105 (1010):2235-43 [Details]
(2010)'Probiotics in perspective'
Shanahan, F. (2010) 'Probiotics in perspective'. Gastroenterology, 139 (66):1808-12 [Details]
(2010)'99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: host-microbe interactions in the gut: target for drug therapy, opportunity for drug discovery'
Shanahan, F. (2010) '99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: host-microbe interactions in the gut: target for drug therapy, opportunity for drug discovery'. Clin Exp Immunol, 160 (11):92-7 [Details]
(2010)'Gut microbes: from bugs to drugs'
Shanahan, F. (2010) 'Gut microbes: from bugs to drugs'. Am J Gastroenterol, 105 (22):275-9 [Details]
(2010)'Pharmabiotic manipulation of the microbiota in gastrointestinal disorders, from rationale to reality'
Shanahan, F.,Collins, S. M. (2010) 'Pharmabiotic manipulation of the microbiota in gastrointestinal disorders, from rationale to reality'. Gastroenterol Clin North Am, 39 (33):721-6 [Details]
(2010)'Probiotic colonization of the adherent mucus layer of HT29MTXE12 cells attenuates Campylobacter jejuni virulence properties'
Alemka, A.,Clyne, M.,Shanahan, F.,Tompkins, T.,Corcionivoschi, N.,Bourke, B. (2010) 'Probiotic colonization of the adherent mucus layer of HT29MTXE12 cells attenuates Campylobacter jejuni virulence properties'. Infect Immun, 78 (66):2812-22 [Details]
(2010)'A molecular analysis of fecal and mucosal bacterial communities in irritable bowel syndrome'
Codling, C.,O'Mahony, L.,Shanahan, F.,Quigley, E. M.,Marchesi, J. R. (2010) 'A molecular analysis of fecal and mucosal bacterial communities in irritable bowel syndrome'. Dig Dis Sci, 55 (22):392-7 [Details]
(2010)'Differential regulation of Toll-like receptor signalling in spleen and Peyer's patch dendritic cells'
Davies, J. M.,MacSharry, J.,Shanahan, F. (2010) 'Differential regulation of Toll-like receptor signalling in spleen and Peyer's patch dendritic cells'. Immunology, 131 (33):438-48 [Details]
(2010)'IBS: An epigenetic perspective'
Dinan, T. G.,Cryan, J.,Shanahan, F.,Keeling, P. W.,Quigley, E. M. (2010) 'IBS: An epigenetic perspective'. Nat Rev Gastroenterol Hepatol, 7 (88):465-71 [Details]
(2010)'Bacterial strain-specific induction of Foxp3+ T regulatory cells is protective in murine allergy models'
Lyons, A.,O'Mahony, D.,O'Brien, F.,MacSharry, J.,Sheil, B.,Ceddia, M.,Russell, W. M.,Forsythe, P.,Bienenstock, J.,Kiely, B.,Shanahan, F.,O'Mahony, L. (2010) 'Bacterial strain-specific induction of Foxp3+ T regulatory cells is protective in murine allergy models'. Clin Exp Allergy, 40 (55):811-9 [Details]
(2010)'Inflammatory bowel disease-from mechanisms to treatment strategies'
Melgar, S.,Shanahan, F. (2010) 'Inflammatory bowel disease-from mechanisms to treatment strategies'. Autoimmunity, 43 (77):463-77 [Details]
(2010)'Technical Advance: Function and efficacy of an {alpha}4-integrin antagonist using bioluminescence imaging to detect leukocyte trafficking in murine experimental colitis'
Murphy, C. T.,Moloney, G.,Macsharry, J.,Haynes, A.,Faivre, E.,Quinlan, A.,McLean, P. G.,Lee, K.,O'Mahony, L.,Shanahan, F.,Melgar, S.,Nally, K. (2010) 'Technical Advance: Function and efficacy of an {alpha}4-integrin antagonist using bioluminescence imaging to detect leukocyte trafficking in murine experimental colitis'. J Leukoc Biol, 88 (66):1271-8 [Details]
(2010)'Down-regulation of p38 mitogen-activated protein kinase activation and proinflammatory cytokine production by mitogen-activated protein kinase inhibitors in inflammatory bowel disease'
Docena, G.,Rovedatti, L.,Kruidenier, L.,Fanning, A.,Leakey, N. A.,Knowles, C. H.,Lee, K.,Shanahan, F.,Nally, K.,McLean, P. G.,Di Sabatino, A.,MacDonald, T. T. (2010) 'Down-regulation of p38 mitogen-activated protein kinase activation and proinflammatory cytokine production by mitogen-activated protein kinase inhibitors in inflammatory bowel disease'. Clin Exp Immunol, 162 (11):108-15108 Globe icon [Details]
(2010)'Phenotypic enhancement of thymidylate synthetase pathway inhibitors following ablation of Neil1 DNA glycosylase/lyase'
Taricani, L.,Shanahan, F.,Pierce, R. H.,Guzi, T. J.,Parry, D. (2010) 'Phenotypic enhancement of thymidylate synthetase pathway inhibitors following ablation of Neil1 DNA glycosylase/lyase'. Cell Cycle, 9 (2424):4876-48834876 Globe icon [Details]
(2010)'Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models'
Murphy, E. F.,Cotter, P. D.,Healy, S.,Marques, T. M.,O'Sullivan, O.,Fouhy, F.,Clarke, S. F.,O'Toole, P. W.,Quigley, E. M.,Stanton, C.,Ross, P. R.,O'Doherty, R. M.,Shanahan, F. (2010) 'Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models'. Gut, 59 (1212):1635-16421635 Globe icon [Details]
(2010)'Use of bioluminescence imaging to track neutrophil migration and its inhibition in experimental colitis'
Murphy, C. T.,Moloney, G.,Hall, L. J.,Quinlan, A.,Faivre, E.,Casey, P.,Shanahan, F.,Melgar, S.,Nally, K. (2010) 'Use of bioluminescence imaging to track neutrophil migration and its inhibition in experimental colitis'. Clin Exp Immunol, 162 (11):188-196188 Globe icon [Details]
(2010)'Impact of administered bifidobacterium on murine host fatty acid composition'
Wall, R.,Ross, R. P.,Shanahan, F.,O'Mahony, L.,Kiely, B.,Quigley, E.,Dinan, T. G.,Fitzgerald, G.,Stanton, C. (2010) 'Impact of administered bifidobacterium on murine host fatty acid composition'. Lipids, 45 (55):429-36 [Details]
(2009)'The vexed relationship between Clostridium difficile and inflammatory bowel disease: an assessment of carriage in an outpatient setting among patients in remission'
Clayton, E. M.,Rea, M. C.,Shanahan, F.,Quigley, E. M.,Kiely, B.,Hill, C.,Ross, R. P. (2009) 'The vexed relationship between Clostridium difficile and inflammatory bowel disease: an assessment of carriage in an outpatient setting among patients in remission'. Am J Gastroenterol, 104 (55):1162-9 [Details]
(2009)'Therapeutic implications of manipulating and mining the microbiota'
Shanahan, F. (2009) 'Therapeutic implications of manipulating and mining the microbiota'. J Physiol, 587 (Pt 17Pt 17):4175-9 [Details]
(2009)'Coeliac disease. Don't forget increased risk of fetal growth restriction'
McCarthy, F. P.,Khashan, A. S.,Quigley, E.,Shanahan, F.,Kenny, L. (2009) 'Coeliac disease. Don't forget increased risk of fetal growth restriction'. Bmj, 338 [Details]
(2009)'Undiagnosed maternal celiac disease in pregnancy and an increased risk of fetal growth restriction'
McCarthy, F. P.,Khashan, A. S.,Quigley, E.,Shanahan, F.,O'Regan, P.,Cronin, C.,Kenny, L. (2009) 'Undiagnosed maternal celiac disease in pregnancy and an increased risk of fetal growth restriction'. J Clin Gastroenterol, 43 (88):792-3 [Details]
(2009)'Metabolic activity of probiotics-oxalate degradation'
Murphy, C.,Murphy, S.,O'Brien, F.,O'Donoghue, M.,Boileau, T.,Sunvold, G.,Reinhart, G.,Kiely, B.,Shanahan, F.,O'Mahony, L. (2009) 'Metabolic activity of probiotics-oxalate degradation'. Vet Microbiol, 136 (1-21-2):100-7 [Details]
(2009)'Modulation of pathogen-induced CCL20 secretion from HT-29 human intestinal epithelial cells by commensal bacteria'
Sibartie, S.,O'Hara, A. M.,Ryan, J.,Fanning, A.,O'Mahony, J.,O'Neill, S.,Sheil, B.,O'Mahony, L.,Shanahan, F. (2009) 'Modulation of pathogen-induced CCL20 secretion from HT-29 human intestinal epithelial cells by commensal bacteria'. BMC Immunol, 10 Globe icon [Details]
(2009)'Loss of vagal anti-inflammatory effect: in vivo visualization and adoptive transfer'
O'Mahony, C.,van der Kleij, H.,Bienenstock, J.,Shanahan, F.,O'Mahony, L. (2009) 'Loss of vagal anti-inflammatory effect: in vivo visualization and adoptive transfer'. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 297 (44) Globe icon [Details]
(2009)'Bacterial signalling overrides cytokine signalling and modifies dendritic cell differentiation'
Davies, J. M.,Sheil, B.,Shanahan, F. (2009) 'Bacterial signalling overrides cytokine signalling and modifies dendritic cell differentiation'. Immunology, 128 (11) Globe icon [Details]
(2009)'Cogan's syndrome: present and future directions'
Murphy, G.,Sullivan, M. O.,Shanahan, F.,Harney, S.,Molloy, M. (2009) 'Cogan's syndrome: present and future directions'. Rheumatol Int, 29 (1010):1117-11211117 Globe icon [Details]
(2009)'Sport and recreation-related injuries and fracture occurrence among emergency department attendees: implications for exercise prescription and injury prevention'
Falvey, E. C.,Eustace, J.,Whelan, B.,Molloy, M. S.,Cusack, S. P.,Shanahan, F.,Molloy, M. G. (2009) 'Sport and recreation-related injuries and fracture occurrence among emergency department attendees: implications for exercise prescription and injury prevention'. 26 (88):590-595590 Globe icon [Details]
(2009)'Culture-independent analysis of desulfovibrios in the human distal colon of healthy, colorectal cancer and polypectomized individuals'
Scanlan, P. D.,Shanahan, F.,Marchesi, J. R. (2009) 'Culture-independent analysis of desulfovibrios in the human distal colon of healthy, colorectal cancer and polypectomized individuals'. FEMS Microbiol Ecol, 69 (22):213-221213 Globe icon [Details]
(2009)'Involvement of T helper type 17 and regulatory T cell activity in Citrobacter rodentium invasion and inflammatory damage'
Symonds, E. L.,Riedel, C. U.,O'Mahony, D.,Lapthorne, S.,O'Mahony, L.,Shanahan, F. (2009) 'Involvement of T helper type 17 and regulatory T cell activity in Citrobacter rodentium invasion and inflammatory damage'. Clin Exp Immunol, 157 (11):148-154148 Globe icon [Details]
(2009)'The evolving epidemiology of inflammatory bowel disease'
Shanahan, F.,Bernstein, C. N. (2009) 'The evolving epidemiology of inflammatory bowel disease'. Curr Opin Gastroenterol, 25 (44):301-305301 Globe icon [Details]
(2009)'Microbiomic analysis of the bifidobacterial population in the human distal gut'
Turroni, F.,Marchesi, J. R.,Foroni, E.,Gueimonde, M.,Shanahan, F.,Margolles, A.,van Sinderen, D.,Ventura, M. (2009) 'Microbiomic analysis of the bifidobacterial population in the human distal gut'. 3 (66):745-751745 Globe icon [Details]
(2009)'Metabolic activity of the enteric microbiota influences the fatty acid composition of murine and porcine liver and adipose tissues'
Wall, R.,Ross, R. P.,Shanahan, F.,O'Mahony, L.,O'Mahony, C.,Coakley, M.,Hart, O.,Lawlor, P.,Quigley, E. M.,Kiely, B.,Fitzgerald, G. F.,Stanton, C. (2009) 'Metabolic activity of the enteric microbiota influences the fatty acid composition of murine and porcine liver and adipose tissues'. 89 (55):1393-14011393 Globe icon [Details]
(2009)'Replication stress activates DNA polymerase alpha-associated Chk1'
Taricani, L.,Shanahan, F.,Parry, D. (2009) 'Replication stress activates DNA polymerase alpha-associated Chk1'. Cell Cycle, 8 (33):482-489482 Globe icon [Details]
(2009)'Exploring the diversity of the bifidobacterial population in the human intestinal tract'
Turroni, F.,Foroni, E.,Pizzetti, P.,Giubellini, V.,Ribbera, A.,Merusi, P.,Cagnasso, P.,Bizzarri, B.,de'Angelis, G. L.,Shanahan, F.,van Sinderen, D.,Ventura, M. (2009) 'Exploring the diversity of the bifidobacterial population in the human intestinal tract'. Appl Environ Microbiol, 75 (66):1534-45 [Details]
(2009)'Portrait of a canine probiotic Bifidobacterium--from gut to gut'
O'Mahony, D.,Murphy, K. B.,MacSharry, J.,Boileau, T.,Sunvold, G.,Reinhart, G.,Kiely, B.,Shanahan, F.,O'Mahony, L. (2009) 'Portrait of a canine probiotic Bifidobacterium--from gut to gut'. Vet Microbiol, 139 (1-21-2):106-12 [Details]
(2009)'The language of medicine: words as servants and scoundrels'
Quigley, E. M.,Shanahan, F. (2009) 'The language of medicine: words as servants and scoundrels'. Clin Med, 9 (22):131-5 [Details]
(2009)'Evaluation of colostrum-derived human mammary-associated serum amyloid A3 (M-SAA3) protein and peptide derivatives for the prevention of enteric infection: in vitro and in murine models of intestinal disease'
Gardiner, G. E.,O'Flaherty, S.,Casey, P. G.,Weber, A.,McDonald, T. L.,Cronin, M.,Hill, C.,Ross, R. P.,Gahan, C. G.,Shanahan, F. (2009) 'Evaluation of colostrum-derived human mammary-associated serum amyloid A3 (M-SAA3) protein and peptide derivatives for the prevention of enteric infection: in vitro and in murine models of intestinal disease'. FEMS Immunol Med Microbiol, 55 (33):404-13 [Details]
(2008)'Disorders of a modern lifestyle: reconciling the epidemiology of inflammatory bowel diseases'
Bernstein, C. N.,Shanahan, F. (2008) 'Disorders of a modern lifestyle: reconciling the epidemiology of inflammatory bowel diseases'. Gut, 57 (99):1185-91 [Details]
(2008)'James Joyce and gastroenterology'
Shanahan, F.,Quigley, E. M. (2008) 'James Joyce and gastroenterology'. Clin Med, 8 (66):632-3 [Details]
(2008)'Enhanced cholinergic-mediated increase in the pro-inflammatory cytokine IL-6 in irritable bowel syndrome: role of muscarinic receptors'
Dinan, T. G.,Clarke, G.,Quigley, E. M.,Scott, L. V.,Shanahan, F.,Cryan, J.,Cooney, J.,Keeling, P. W. (2008) 'Enhanced cholinergic-mediated increase in the pro-inflammatory cytokine IL-6 in irritable bowel syndrome: role of muscarinic receptors'. Am J Gastroenterol, 103 (1010):2570-6 [Details]
(2008)'Tryptophan catabolism in females with irritable bowel syndrome: relationship to interferon-gamma, severity of symptoms and psychiatric co-morbidity'
Fitzgerald, P.,Cassidy Eugene, M.,Clarke, G.,Scully, P.,Barry, S.,Quigley Eamonn, M. M.,Shanahan, F.,Cryan, J.,Dinan Timothy, G. (2008) 'Tryptophan catabolism in females with irritable bowel syndrome: relationship to interferon-gamma, severity of symptoms and psychiatric co-morbidity'. Neurogastroenterol Motil, 20 (1212):1291-7 [Details]
(2008)'Are patients with IBD knowledgeable about the risks of their medications?'
Keohane, J.,Shanahan, F. (2008) 'Are patients with IBD knowledgeable about the risks of their medications?'. Inflamm Bowel Dis, 14 Suppl 2 [Details]
(2008)'Mucosal cytokine imbalance in irritable bowel syndrome'
Macsharry, J.,O'Mahony, L.,Fanning, A.,Bairead, E.,Sherlock, G.,Tiesman, J.,Fulmer, A.,Kiely, B.,Dinan, T. G.,Shanahan, F.,Quigley, E. M. (2008) 'Mucosal cytokine imbalance in irritable bowel syndrome'. Scand J Gastroenterol, 43 (1212):1467-76 [Details]
(2008)'High levels of Lymphotoxin-Beta (LT-Beta) gene expression in rheumatoid arthritis synovium: clinical and cytokine correlations'
O'Rourke, K. P.,O'Donoghue, G.,Adams, C.,Mulcahy, H.,Molloy, C.,Silke, C.,Molloy, M.,Shanahan, F.,O'Gara, F. (2008) 'High levels of Lymphotoxin-Beta (LT-Beta) gene expression in rheumatoid arthritis synovium: clinical and cytokine correlations'. Rheumatol Int, 28 (1010):979-986979 Globe icon [Details]
(2008)'Human methanogen diversity and incidence in healthy and diseased colonic groups using mcrA gene analysis'
Scanlan, P. D.,Shanahan, F.,Marchesi, J. R. (2008) 'Human methanogen diversity and incidence in healthy and diseased colonic groups using mcrA gene analysis'. BMC Microbiol, 8 Globe icon [Details]
(2008)'Drug interactions in inflammatory bowel disease'
Irving, P. M.,Shanahan, F.,Rampton, D. S. (2008) 'Drug interactions in inflammatory bowel disease'. 103 (11):207-219207 Globe icon [Details]
(2008)'Bad language in gastroenterology'
Shanahan, F.,Quigley, E. M. (2008) 'Bad language in gastroenterology'. Curr Gastroenterol Rep, 10 (22):91-3 [Details]
(2008)'Protective effects of Lactobacillus rhamnosus [corrected] and Bifidobacterium infantis in murine models for colitis do not involve the vagus nerve'
van der Kleij, H.,O'Mahony, C.,Shanahan, F.,O'Mahony, L.,Bienenstock, J. (2008) 'Protective effects of Lactobacillus rhamnosus [corrected] and Bifidobacterium infantis in murine models for colitis do not involve the vagus nerve'. Am J Physiol Regul Integr Comp Physiol, 295 (44) [Details]
(2008)'Prostaglandin E2 stimulates Fas ligand expression via the EP1 receptor in colon cancer cells'
O'Callaghan, G.,Kelly, J.,Shanahan, F.,Houston, A. (2008) 'Prostaglandin E2 stimulates Fas ligand expression via the EP1 receptor in colon cancer cells'. Br J Cancer, 99 (33):502-12 [Details]
(2008)'Commensal-induced regulatory T cells mediate protection against pathogen-stimulated NF-kappaB activation'
O'Mahony, C.,Scully, P.,O'Mahony, D.,Murphy, S.,O'Brien, F.,Lyons, A.,Sherlock, G.,MacSharry, J.,Kiely, B.,Shanahan, F.,O'Mahony, L. (2008) 'Commensal-induced regulatory T cells mediate protection against pathogen-stimulated NF-kappaB activation'. PLoS Pathog, 4 (88) [Details]
(2008)'Evidence of an enhanced central 5HT response in irritable bowel syndrome and in the rat maternal separation model'
O'Mahony, S.,Chua, A. S.,Quigley, E. M.,Clarke, G.,Shanahan, F.,Keeling, P. W.,Dinan, T. G. (2008) 'Evidence of an enhanced central 5HT response in irritable bowel syndrome and in the rat maternal separation model'. Neurogastroenterol Motil, 20 (66):680-8 [Details]
(2008)'Culture-independent analysis of the gut microbiota in colorectal cancer and polyposis'
Scanlan, P. D.,Shanahan, F.,Clune, Y.,Collins, J. K.,O'Sullivan, G. C.,O'Riordan, M.,Holmes, E.,Wang, Y.,Marchesi, J. R. (2008) 'Culture-independent analysis of the gut microbiota in colorectal cancer and polyposis'. Environ Microbiol, 10 (33):789-98 [Details]
(2008)'From bugs to drugs--mining the gut microbiota'
Shanahan, F. (2008) 'From bugs to drugs--mining the gut microbiota'. Curr Gastroenterol Rep, 10 (66):515-6 [Details]
(2008)'Crohn's disease: factors associated with exposure to high levels of diagnostic radiation'
Desmond, A. N.,O'Regan, K.,Curran, C.,McWilliams, S.,Fitzgerald, T.,Maher, M. M.,Shanahan, F. (2008) 'Crohn's disease: factors associated with exposure to high levels of diagnostic radiation'. Gut, 57 (1111):1524-9 [Details]
(2007)'Rapid and noninvasive metabonomic characterization of inflammatory bowel disease'
Marchesi, J. R.,Holmes, E.,Khan, F.,Kochhar, S.,Scanlan, P.,Shanahan, F.,Wilson, I. D.,Wang, Y. (2007) 'Rapid and noninvasive metabonomic characterization of inflammatory bowel disease'. J Proteome Res, 6 (22):546-51 [Details]
(2007)'Colitis-associated cancer and dysplasia surveillance: an opposing perspective'
Shanahan, F. (2007) 'Colitis-associated cancer and dysplasia surveillance: an opposing perspective'. Curr Gastroenterol Rep, 9 (33):175-6 [Details]
(2007)'Steroid allergy in patients with inflammatory bowel disease'
Malik, M.,Tobin, A. M.,Shanahan, F.,O'Morain, C.,Kirby, B.,Bourke, J. (2007) 'Steroid allergy in patients with inflammatory bowel disease'. British Journal of Dermatology, 157 (55):967-969967 Globe icon [Details]
(2007)'The normal intestinal microbiota'
Marchesi, J.,Shanahan, F. (2007) 'The normal intestinal microbiota'. Curr Opin Infect Dis, 20 (55):508-513508 Globe icon [Details]
(2007)'Salmonella typhimurium stimulation combined with tumour-derived heat shock proteins induces potent dendritic cell anti-tumour responses in a murine model'
Shilling, D. A.,Smith, M. J.,Tyther, R.,Sheehan, D.,England, K.,Kavanagh, E. G.,Redmond, H. P.,Shanahan, F.,O'Mahony, L. (2007) 'Salmonella typhimurium stimulation combined with tumour-derived heat shock proteins induces potent dendritic cell anti-tumour responses in a murine model'. Clin Exp Immunol, 149 (11):109-116109 Globe icon [Details]
(2007)'Intestinal tuberculosis mimicking Crohn's disease: lessons relearned in a new era'
Sibartie, V.,Kirwan, W. O.,O'Mahony, S.,Stack, W.,Shanahan, F. (2007) 'Intestinal tuberculosis mimicking Crohn's disease: lessons relearned in a new era'. Eur J Gastroenterol Hepatol, 19 (44):347-349347 Globe icon [Details]
(2007)'Probiotic effects on inflammatory bowel disease'
Sheil, B.,Shanahan, F.,O'Mahony, L. (2007) 'Probiotic effects on inflammatory bowel disease'. 137 (33) Globe icon [Details]
(2007)'Mechanisms of action of probiotics in intestinal diseases'
O'Hara, A. M.,Shanahan, F. (2007) 'Mechanisms of action of probiotics in intestinal diseases'. ScientificWorldJournal, 7 :31-4631 Globe icon [Details]
(2007)'In vitro replication models for the hepatitis C virus'
Sheehy, P.,Mullan, B.,Moreau, I.,Kenny-Walsh, E.,Shanahan, F.,Scallan, M.,Fanning, L. J. (2007) 'In vitro replication models for the hepatitis C virus'. J Viral Hepat, 14 (11):2-102 Globe icon [Details]
(2007)'Gut microbiota: mining for therapeutic potential'
O'Hara, A. M.,Shanahan, F. (2007) 'Gut microbiota: mining for therapeutic potential'. Clin Gastroenterol Hepatol, 5 (33):274-84 [Details]
(2007)'Pyrazolo[1,5-a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2'
Paruch, K.,Dwyer, M. P.,Alvarez, C.,Brown, C.,Chan, T. Y.,Doll, R. J.,Keertikar, K.,Knutson, C.,McKittrick, B.,Rivera, J.,Rossman, R.,Tucker, G.,Fischmann, T. O.,Hruza, A.,Madison, V.,Nomeir, A. A.,Wang, Y.,Lees, E.,Parry, D.,Sgambellone, N.,Seghezzi, W.,Schultz, L.,Shanahan, F.,Wiswell, D.,Xu, X.,Zhou, Q.,James, R. A.,Paradkar, V. M.,Park, H.,Rokosz, L. R.,Stauffer, T. M.,Guzi, T. J. (2007) 'Pyrazolo[1,5-a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2'. Bioorg Med Chem Lett, 17 (2222):6220-3 [Details]
(2007)'Antimicrobial activity of lacticin 3,147 against clinical Clostridium difficile strains'
Rea, M. C.,Clayton, E.,O'Connor, P. M.,Shanahan, F.,Kiely, B.,Ross, R. P.,Hill, C. (2007) 'Antimicrobial activity of lacticin 3,147 against clinical Clostridium difficile strains'. J Med Microbiol, 56 (Pt 7Pt 7):940-6 [Details]
(2007)'Chronic gastroenterologic and hepatic disorders'
Shanahan, F. (2007) 'Chronic gastroenterologic and hepatic disorders'. Best Pract Res Clin Gastroenterol, 21 (55):753-4 [Details]
(2007)'Irritable bowel syndrome: shifting the focus toward the gut microbiota'
Shanahan, F. (2007) 'Irritable bowel syndrome: shifting the focus toward the gut microbiota'. Gastroenterology, 133 (11):340-2 [Details]
(2007)'Versatile templates for the development of novel kinase inhibitors: Discovery of novel CDK inhibitors'
Dwyer, M. P.,Paruch, K.,Alvarez, C.,Doll, R. J.,Keertikar, K.,Duca, J.,Fischmann, T. O.,Hruza, A.,Madison, V.,Lees, E.,Parry, D.,Seghezzi, W.,Sgambellone, N.,Shanahan, F.,Wiswell, D.,Guzi, T. J. (2007) 'Versatile templates for the development of novel kinase inhibitors: Discovery of novel CDK inhibitors'. Bioorg Med Chem Lett, 17 (2222):6216-62196216 Globe icon [Details]
(2006)'Hypothalamic-pituitary-gut axis dysregulation in irritable bowel syndrome: plasma cytokines as a potential biomarker?'
Dinan, T. G.,Quigley, E. M.,Ahmed, S. M.,Scully, P.,O'Brien, S.,O'Mahony, L.,O'Mahony, S.,Shanahan, F.,Keeling, P. W. (2006) 'Hypothalamic-pituitary-gut axis dysregulation in irritable bowel syndrome: plasma cytokines as a potential biomarker?'. Gastroenterology, 130 (22):304-11 [Details]
(2006)'Medicine in the age of Ulysses : James Joyce's portrait of life, medicine, and disease on a Dublin day a century ago'
Shanahan, F.,Quigley, E. M. (2006) 'Medicine in the age of Ulysses : James Joyce's portrait of life, medicine, and disease on a Dublin day a century ago'. Perspect Biol Med, 49 (22):276-85 [Details]
(2006)'Culture-independent analyses of temporal variation of the dominant fecal microbiota and targeted bacterial subgroups in Crohn's disease'
Scanlan, P. D.,Shanahan, F.,O'Mahony, C.,Marchesi, J. R. (2006) 'Culture-independent analyses of temporal variation of the dominant fecal microbiota and targeted bacterial subgroups in Crohn's disease'. J Clin Microbiol, 44 (1111):3980-39883980 Globe icon [Details]
(2006)'Bcl-x(L) expression in vivo in rheumatoid synovium'
Busteed, S.,Bennett, M. W.,Molloy, C.,Houston, A.,Stone, M. A.,Shanahan, F.,Molloy, M. G.,O'Connell, J. (2006) 'Bcl-x(L) expression in vivo in rheumatoid synovium'. Clin Rheumatol, 25 (66):789-793789 Globe icon [Details]
(2006)'The gut flora as a forgotten organ'
O'Hara, A. M.,Shanahan, F. (2006) 'The gut flora as a forgotten organ'. EMBO Rep, 7 (77):688-693688 Globe icon [Details]
(2006)'Determinants of vitamin D status in adult Crohn's disease patients, with particular emphasis on supplemental vitamin D use'
Gilman, J.,Shanahan, F.,Cashman, K. D. (2006) 'Determinants of vitamin D status in adult Crohn's disease patients, with particular emphasis on supplemental vitamin D use'. Eur J Clin Nutr, 60 (77):889-896889 Globe icon [Details]
(2006)'Role of interleukin (IL-10) in probiotic-mediated immune modulation: an assessment in wild-type and IL-10 knock-out mice'
Sheil, B.,MacSharry, J.,O'Callaghan, L.,O'Riordan, A.,Waters, A.,Morgan, J.,Collins, J. K.,O'Mahony, L.,Shanahan, F. (2006) 'Role of interleukin (IL-10) in probiotic-mediated immune modulation: an assessment in wild-type and IL-10 knock-out mice'. Clin Exp Immunol, 144 (22):273-280273 Globe icon [Details]
(2006)'Multireplicon genome architecture of Lactobacillus salivarius'
Claesson, M. J.,Li, Y.,Leahy, S.,Canchaya, C.,van Pijkeren, J. P.,Cerdeno-Tarraga, A. M.,Parkhill, J.,Flynn, S.,O'Sullivan, G. C.,Collins, J. K.,Higgins, D.,Shanahan, F.,Fitzgerald, G. F.,van Sinderen, D.,O'Toole, P. W. (2006) 'Multireplicon genome architecture of Lactobacillus salivarius'. Proc Natl Acad Sci U S A, 103 (1717):6718-67236718 Globe icon [Details]
(2006)'Altered levels of biochemical indices of bone turnover and bone-related vitamins in patients with Crohn's disease and ulcerative colitis'
Gilman, J.,Shanahan, F.,Cashman, K. D. (2006) 'Altered levels of biochemical indices of bone turnover and bone-related vitamins in patients with Crohn's disease and ulcerative colitis'. Aliment Pharmacol Ther, 23 (77):1007-10161007 Globe icon [Details]
(2006)'CD38 is associated with premenopausal and postmenopausal bone mineral density and postmenopausal bone loss'
Drummond, F. J.,Mackrill, J. J.,O'Sullivan, K.,Daly, M.,Shanahan, F.,Molloy, M. G. (2006) 'CD38 is associated with premenopausal and postmenopausal bone mineral density and postmenopausal bone loss'. J Bone Miner Metab, 24 (11):28-3528 Globe icon [Details]
(2006)'Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome'
Whorwell, P. J.,Altringer, L.,Morel, J.,Bond, Y.,Charbonneau, D.,O'Mahony, L.,Kiely, B.,Shanahan, F.,Quigley, E. M. (2006) 'Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome'. Am J Gastroenterol, 101 (77):1581-90 [Details]
(2006)'Functional modulation of human intestinal epithelial cell responses by Bifidobacterium infantis and Lactobacillus salivarius'
O'Hara, A. M.,O'Regan, P.,Fanning, A.,O'Mahony, C.,Macsharry, J.,Lyons, A.,Bienenstock, J.,O'Mahony, L.,Shanahan, F. (2006) 'Functional modulation of human intestinal epithelial cell responses by Bifidobacterium infantis and Lactobacillus salivarius'. Immunology, 118 (22):202-15 [Details]
(2006)'Fas ligand expression in human and mouse cancer cell lines; a caveat on over-reliance on mRNA data'
Ryan, A. E.,Lane, S.,Shanahan, F.,O'Connell, J.,Houston, A. M. (2006) 'Fas ligand expression in human and mouse cancer cell lines; a caveat on over-reliance on mRNA data'. J Carcinog, 5 [Details]
(2006)'Fas ligand promotes tumor immune evasion of colon cancer in vivo'
Ryan, A. E.,Shanahan, F.,O'Connell, J.,Houston, A. M. (2006) 'Fas ligand promotes tumor immune evasion of colon cancer in vivo'. Cell Cycle, 5 (33):246-9 [Details]
(2006)'Differential cytokine response from dendritic cells to commensal and pathogenic bacteria in different lymphoid compartments in humans'
O'Mahony, L.,O'Callaghan, L.,McCarthy, J.,Shilling, D.,Scully, P.,Sibartie, S.,Kavanagh, E.,Kirwan, W. O.,Redmond, H. P.,Collins, J. K.,Shanahan, F.; (2006) 'Differential cytokine response from dendritic cells to commensal and pathogenic bacteria in different lymphoid compartments in humans'. American Journal of Physiology-Gastrointestinal and Liver Physiology, 290 (44) Globe icon [Details]
(2005)'The mycobacteria story in Crohn's disease'
Shanahan, F.,O'Mahony, J. (2005) 'The mycobacteria story in Crohn's disease'. 100 (77):1537-15381537 Globe icon [Details]
(2005)'Seasonality of vitamin D status and bone turnover in patients with Crohn's disease'
McCarthy, D.,Duggan, P.,O'Brien, M.,Kiely, M.,McCarthy, J.,Shanahan, F.,Cashman, K. D. (2005) 'Seasonality of vitamin D status and bone turnover in patients with Crohn's disease'. Aliment Pharmacol Ther, 21 (99):1073-10831073 Globe icon [Details]
(2005)'A strategy for obtaining near full-length HCV cDNA clones (assemblicons) by assembly PCR'
Sheehy, P.,Scallan, M.,Kenny-Walsh, E.,Shanahan, F.,Fanning, L. J. (2005) 'A strategy for obtaining near full-length HCV cDNA clones (assemblicons) by assembly PCR'. J Virol Methods, 123 (22):115-124115 Globe icon [Details]
(2005)'Viral load change and sequential evolution of entire hepatitis C virus genome in Irish recipients of single source-contaminated anti-D immunoglobulin*'
Itakura, J.,Nagayama, K.,Enomoto, N.,Hamano, K.,Sakamoto, N.,Fanning, L. J.,Kenny-Walsh, E.,Shanahan, F.,Watanabe, M. (2005) 'Viral load change and sequential evolution of entire hepatitis C virus genome in Irish recipients of single source-contaminated anti-D immunoglobulin*'. J Viral Hepat, 12 (66):594-603 [Details]
(2005)'Correlation of probiotic Lactobacillus salivarius growth phase with its cell wall-associated proteome'
Kelly, P.,Maguire, P. B.,Bennett, M.,Fitzgerald, D. J.,Edwards, R. J.,Thiede, B.,Treumann, A.,Collins, J. K.,O'Sullivan, G. C.,Shanahan, F.,Dunne, C. (2005) 'Correlation of probiotic Lactobacillus salivarius growth phase with its cell wall-associated proteome'. FEMS Microbiol Lett, 252 (11):153-9 [Details]
(2005)'Physiological basis for novel drug therapies used to treat the inflammatory bowel diseases I. Pathophysiological basis and prospects for probiotic therapy in inflammatory bowel disease'
Shanahan, F. (2005) 'Physiological basis for novel drug therapies used to treat the inflammatory bowel diseases I. Pathophysiological basis and prospects for probiotic therapy in inflammatory bowel disease'. Am J Physiol Gastrointest Liver Physiol, 288 (33) [Details]
(2005)'IgG-mediated food intolerance in irritable bowel syndrome: a real phenomenon or an epiphenomenom?'
Shanahan, F.,Whorwell, P. J. (2005) 'IgG-mediated food intolerance in irritable bowel syndrome: a real phenomenon or an epiphenomenom?'. Am J Gastroenterol, 100 (77):1558-9 [Details]
(2005)'Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles'
O'Mahony, L.,McCarthy, J.,Kelly, P.,Hurley, G.,Luo, F.,Chen, K.,O'Sullivan, G. C.,Kiely, B.,Collins, J. K.,Shanahan, F.,Quigley, E. M. (2005) 'Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles'. Gastroenterology, 128 (33):541-51 [Details]
(2005)'Probiotics: an emerging therapy'
O'Sullivan, G. C.,Kelly, P.,O'Halloran, S.,Collins, C.,Collins, J. K.,Dunne, C.,Shanahan, F. (2005) 'Probiotics: an emerging therapy'. Curr Pharm Des, 11 (11):3-10 [Details]
(2005)'Addressing the Fas counterattack controversy: blocking fas ligand expression suppresses tumor immune evasion of colon cancer in vivo'
Ryan, A. E.,Shanahan, F.,O'Connell, J.,Houston, A. M. (2005) 'Addressing the Fas counterattack controversy: blocking fas ligand expression suppresses tumor immune evasion of colon cancer in vivo'. Cancer Res, 65 (2121):9817-23 [Details]
(2005)'Targeting the Fas/Fas ligand pathway in cancer'
O'Brien, D. I.,Nally, K.,Kelly, R. G.,O'Connor, T. M.,Shanahan, F.,O'Connell, J. (2005) 'Targeting the Fas/Fas ligand pathway in cancer'. Expert Opin Ther Targets, 9 (55):1031-10441031 Globe icon [Details]
(2004)'The role of substance P in inflammatory disease'
O'Connor, T. M.,O'Connell, J.,O'Brien, D. I.,Goode, T.,Bredin, C. P.,Shanahan, F. (2004) 'The role of substance P in inflammatory disease'. J Cell Physiol, 201 (22):167-180167 Globe icon [Details]
(2004)'Role for BRG1 in cell cycle control and tumor suppression'
Hendricks, K. B.,Shanahan, F.,Lees, E. (2004) 'Role for BRG1 in cell cycle control and tumor suppression'. Mol Cell Biol, 24 (11):362-376362 Globe icon [Details]
(2004)'Is the mucosal route of administration essential for probiotic function? Subcutaneous administration is associated with attenuation of murine colitis and arthritis'
Sheil, B.,McCarthy, J.,O'Mahony, L.,Bennett, M. W.,Ryan, P.,Fitzgibbon, J. J.,Kiely, B.,Collins, J. K.,Shanahan, F. (2004) 'Is the mucosal route of administration essential for probiotic function? Subcutaneous administration is associated with attenuation of murine colitis and arthritis'. Gut, 53 (55):694-700694 Globe icon [Details]
(2004)'Persistence of hepatitis C virus in a white population: associations with human leukocyte antigen class 1'
Fanning, L. J.,Kenny-Walsh, E.,Shanahan, F. (2004) 'Persistence of hepatitis C virus in a white population: associations with human leukocyte antigen class 1'. Hum Immunol, 65 (77):745-51 [Details]
(2004)'Clinical examination of the gastrointestinal system in the 21st century--is the emphasis right?'
Sibartie, V.,Shanahan, F. (2004) 'Clinical examination of the gastrointestinal system in the 21st century--is the emphasis right?'. Am J Gastroenterol, 99 (1010):1874-5 [Details]
(2004)'Celiac disease and the transition from childhood to adulthood: a 28-year follow-up'
O'Leary, C.,Wieneke, P.,Healy, M.,Cronin, C.,O'Regan, P.,Shanahan, F. (2004) 'Celiac disease and the transition from childhood to adulthood: a 28-year follow-up'. Am J Gastroenterol, 99 (1212):2437-41 [Details]
(2004)'Thromboembolism--an important manifestation of inflammatory bowel disease'
Quera, R.,Shanahan, F. (2004) 'Thromboembolism--an important manifestation of inflammatory bowel disease'. Am J Gastroenterol, 99 (1010):1971-3 [Details]
(2004)'Bacterial DNA within granulomas of patients with Crohn's disease--detection by laser capture microdissection and PCR'
Ryan, P.,Kelly, R. G.,Lee, G.,Collins, J. K.,O'Sullivan, G. C.,O'Connell, J.,Shanahan, F. (2004) 'Bacterial DNA within granulomas of patients with Crohn's disease--detection by laser capture microdissection and PCR'. Am J Gastroenterol, 99 (88):1539-43 [Details]
(2004)'Making microbes work for mankind--clever trick or a glimpse of the future for IBD treatment?'
Shanahan, F. (2004) 'Making microbes work for mankind--clever trick or a glimpse of the future for IBD treatment?'. Gastroenterology, 127 (22):667-8 [Details]
(2004)'Probiotics and the immune response: how much can we expect?'
Shanahan, F. (2004) 'Probiotics and the immune response: how much can we expect?'. J Pediatr Gastroenterol Nutr, 39 Suppl 3 [Details]
(2004)'Probiotics in inflammatory bowel disease--therapeutic rationale and role'
Shanahan, F. (2004) 'Probiotics in inflammatory bowel disease--therapeutic rationale and role'. Adv Drug Deliv Rev, 56 (66):809-18 [Details]
(2004)'Antibiotics as a first-line therapy for Crohn's disease: is there any consensus?'
Shanahan, F.,Bernstein, C. N. (2004) 'Antibiotics as a first-line therapy for Crohn's disease: is there any consensus?'. Inflamm Bowel Dis, 10 (33):324-6 [Details]
(2004)'CON: surveillance for ulcerative colitis-associated cancer: time to change the endoscopy and the microscopy'
Shanahan, F.,Quera, R. (2004) 'CON: surveillance for ulcerative colitis-associated cancer: time to change the endoscopy and the microscopy'. Am J Gastroenterol, 99 (99):1633-6 [Details]
(2004)'Substance P and other neuropeptides do not induce mediator release in isolated human intestinal mast cells'
Bischoff, S. C.,Schwengberg, S.,Lorentz, A.,Manns, M. P.,Bektas, H.,Sann, H.,Levi-Schaffer, F.,Shanahan, F.,Schemann, M. (2004) 'Substance P and other neuropeptides do not induce mediator release in isolated human intestinal mast cells'. Neurogastroenterology and Motility, 16 (22):185-193185 Globe icon [Details]
(2004)'Do Taq-generated RT-PCR products from RNA viruses accurately reflect viral genetic heterogeneity?'
Mullan, B.,Sheehy, P.,Shanahan, F.,Fanning, L. (2004) 'Do Taq-generated RT-PCR products from RNA viruses accurately reflect viral genetic heterogeneity?'. J Viral Hepat, 11 (22):108-114108 Globe icon [Details]
(2004)'Prevalence of bone marrow micrometastases in esophagogastric cancer patients with and without neoadjuvant chemoradiotherapy'
Ryan, P.,McCarthy, S.,Kelly, J.,Collins, J. K.,Dunne, C.,Grogan, L.,Breathnach, O.,Shanahan, F.,Carey, P. D.,Walsh, T. N.,O'Sullivan, G. C. (2004) 'Prevalence of bone marrow micrometastases in esophagogastric cancer patients with and without neoadjuvant chemoradiotherapy'. 117 (11):121-126121 Globe icon [Details]
(2004)'Host-flora interactions in inflammatory bowel disease'
Shanahan, F. (2004) 'Host-flora interactions in inflammatory bowel disease'. Inflamm Bowel Dis, 10 Globe icon [Details]
(2004)'Vitamin K status in patients with Crohn's disease and relationship to bone turnover'
Duggan, P.,O'Brien, M.,Kiely, M.,McCarthy, J.,Shanahan, F.,Cashman, K. D. (2004) 'Vitamin K status in patients with Crohn's disease and relationship to bone turnover'. 99 (1111):2178-21852178 Globe icon [Details]
(2003)'Effective therapy for advanced gastrointestinal stromal tumors'
Collins, C. G.,O'Sullivan, G. C.,Shanahan, F. (2003) 'Effective therapy for advanced gastrointestinal stromal tumors'. Gastroenterology, 124 (44):1151-3 [Details]
(2003)'Oral immune tolerance to tumor specific antigens may confer growth advantage to esophageal and gastric cancers'
O'Brien, M. G.,Collins, C. G.,Collins, J. K.,Shanahan, F.,O'Sullivan, G. C. (2003) 'Oral immune tolerance to tumor specific antigens may confer growth advantage to esophageal and gastric cancers'. 16 (33):218-223218 Globe icon [Details]
(2003)'Manipulation of the bacterial flora in inflammatory bowel disease'
Marteau, P.,Seksik, P.,Shanahan, F. (2003) 'Manipulation of the bacterial flora in inflammatory bowel disease'. Best Pract Res Clin Gastroenterol, 17 (11):47-61 [Details]
(2003)'Basic aspects and pharmacology of probiotics: an overview of pharmacokinetics, mechanisms of action and side-effects'
Marteau, P.,Shanahan, F. (2003) 'Basic aspects and pharmacology of probiotics: an overview of pharmacokinetics, mechanisms of action and side-effects'. Best Pract Res Clin Gastroenterol, 17 (55):725-40 [Details]
(2003)'Double blind, placebo controlled trial of two probiotic strains in interleukin 10 knockout mice and mechanistic link with cytokine balance'
McCarthy, J.,O'Mahony, L.,O'Callaghan, L.,Sheil, B.,Vaughan, E. E.,Fitzsimons, N.,Fitzgibbon, J.,O'Sullivan, G. C.,Kiely, B.,Collins, J. K.,Shanahan, F. (2003) 'Double blind, placebo controlled trial of two probiotic strains in interleukin 10 knockout mice and mechanistic link with cytokine balance'. Gut, 52 (77):975-80 [Details]
(2003)'Acromegaly and colorectal cancer: a comprehensive review of epidemiology, biological mechanisms, and clinical implications'
Renehan, A. G.,O'Connell, J.,O'Halloran, D.,Shanahan, F.,Potten, C. S.,O'Dwyer, S. T.,Shalet, S. M. (2003) 'Acromegaly and colorectal cancer: a comprehensive review of epidemiology, biological mechanisms, and clinical implications'. Horm Metab Res, 35 (11-1211-12):712-25 [Details]
(2003)'Review article: colitis-associated cancer -- time for new strategies'
Shanahan, F. (2003) 'Review article: colitis-associated cancer -- time for new strategies'. Aliment Pharmacol Ther, 18 Suppl 2 :6-9 [Details]
(2003)'Probiotics: a perspective on problems and pitfalls'
Shanahan, F. (2003) 'Probiotics: a perspective on problems and pitfalls'. Scand J Gastroenterol Suppl, (237237):34-6 [Details]
(2003)'Screening for asymptomatic celiac disease among patients referred for bone densitometry measurement'
Drummond, F. J.,Annis, P.,O'Sullivan, K.,Wynne, F.,Daly, M.,Shanahan, F.,Quane, K. A.,Molloy, M. G. (2003) 'Screening for asymptomatic celiac disease among patients referred for bone densitometry measurement'. Bone, 33 (66):970-974970 Globe icon [Details]
(2003)'Fas ligand expressed in colon cancer is not associated with increased apoptosis of tumor cells in vivo'
Houston, A.,Waldron-Lynch, F. D.,Bennett, M. W.,Roche, D.,O'Sullivan, G. C.,Shanahan, F.,O'Connell, J. (2003) 'Fas ligand expressed in colon cancer is not associated with increased apoptosis of tumor cells in vivo'. 107 (22):209-214209 Globe icon [Details]
(2003)'Fas ligand mediates immune privilege and not inflammation in human colon cancer, irrespective of TGF-beta expression'
Houston, A.,Bennett, M. W.,O'Sullivan, G. C.,Shanahan, F.,O'Connell, J. (2003) 'Fas ligand mediates immune privilege and not inflammation in human colon cancer, irrespective of TGF-beta expression'. Br J Cancer, 89 (77):1345-13511345 Globe icon [Details]
(2003)'Neurokinin-1 receptor (NK-1R) expression is induced in human colonic epithelial cells by proinflammatory cytokines and mediates proliferation in response to substance P'
Goode, T.,O'Connor, T.,Hopkins, A.,Moriarty, D.,O'Sullivan, G. C.,Collins, J. K.,O'Donoghue, D.,Baird, A. W.,O'Connell, J.,Shanahan, F. (2003) 'Neurokinin-1 receptor (NK-1R) expression is induced in human colonic epithelial cells by proinflammatory cytokines and mediates proliferation in response to substance P'. J Cell Physiol, 197 (11):30-4130 Globe icon [Details]
(2003)'Upregulation of neurokinin-1 receptor expression in the lungs of patients with sarcoidosis'
O'Connor, T. M.,O'Connell, J.,O'Brien, D. I.,Bennett, M. W.,Goode, T.,Burke, L.,Bredin, C. P.,Shanahan, F. (2003) 'Upregulation of neurokinin-1 receptor expression in the lungs of patients with sarcoidosis'. J Clin Immunol, 23 (55):425-435425 Globe icon [Details]
(2003)'Is nutrition an aetiological factor for inflammatory bowel disease?'
Cashman, K. D.,Shanahan, F. (2003) 'Is nutrition an aetiological factor for inflammatory bowel disease?'. Eur J Gastroenterol Hepatol, 15 (66):607-613607 Globe icon [Details]
(2003)'Suggestive linkage of 2p22-25 and 11q12-13 with low bone mineral density at the lumbar spine in the Irish population'
Wynne, F.,Drummond, F. J.,Daly, M.,Brown, M.,Shanahan, F.,Molloy, M. G.,Quane, K. A. (2003) 'Suggestive linkage of 2p22-25 and 11q12-13 with low bone mineral density at the lumbar spine in the Irish population'. Calcif Tissue Int, 72 (66):651-658651 Globe icon [Details]
(2003)'The prophylactic use of a proton pump inhibitor before food and alcohol'
O'Leary, C.,McCarthy, J.,Humphries, M.,Shanahan, F.,Quigley, E. (2003) 'The prophylactic use of a proton pump inhibitor before food and alcohol'. Aliment Pharmacol Ther, 17 (55):683-686683 Globe icon [Details]
(2003)'Association of NOD2 with Crohn's disease in a homogenous Irish population'
Bairead, E.,Harmon, D. L.,Curtis, A. M.,Kelly, Y.,O'Leary, C.,Gardner, M.,Leahy, D. T.,Vaughan, P.,Keegan, D.,O'Morain, C.,O'Donoghue, D.,Shanahan, F.,Parfrey, N. A.,Quane, K. A. (2003) 'Association of NOD2 with Crohn's disease in a homogenous Irish population'. 11 (33):237-244237 Globe icon [Details]
(2003)'Exploring the iceberg--the spectrum of celiac disease'
Cronin, C. C.,Shanahan, F. (2003) 'Exploring the iceberg--the spectrum of celiac disease'. Am J Gastroenterol, 98 (33):518-20 [Details]
(2002)'The prevalence of coeliac disease among female subjects having bone densitometry'
O'Leary, C.,Feighery, C.,Feighery, A.,Quane, K.,Shanahan, F.,Molloy, M.,Cronin, C. C. (2002) 'The prevalence of coeliac disease among female subjects having bone densitometry'. Ir J Med Sci, 171 (33):145-147145 Globe icon [Details]
(2002)'Genotoxicity of fecal water in a free-living Irish population'
Woods, J. A.,Dunne, C.,Collins, J. K.,Shanahan, F.,O'Brien, N. M. (2002) 'Genotoxicity of fecal water in a free-living Irish population'. 42 (11):62-6962 Globe icon [Details]
(2002)'Activation of the p38 MAPK and ERK1/2 pathways is required for Fas-induced IL-8 production in colonic epithelial cells'
O'Brien, D.,O'Connor, T.,Shanahan, F.,O'Connell, J. (2002) 'Activation of the p38 MAPK and ERK1/2 pathways is required for Fas-induced IL-8 production in colonic epithelial cells'. Cell Signaling, Transcription, and Translation as Therapeutic Targets, 973 :161-165161 Globe icon [Details]
(2002)'Role of probiotics in the treatment of intestinal infections and inflammation'
Dunne, C.,Shanahan, F. (2002) 'Role of probiotics in the treatment of intestinal infections and inflammation'. Curr Opin Gastroenterol, 18 (11):40-4540 Globe icon [Details]
(2002)'Gut flora in gastrointestinal disease'
Shanahan, F. (2002) 'Gut flora in gastrointestinal disease'. European Journal of Surgery, 168 :47-5247 Globe icon [Details]
(2002)'Nested RT-PCR. Sensitivity controls are essential to determine the biological significance of detected mRNA'
Goode, T.,Ho, W. Z.,O'Connor, T.,Busteed, S.,Douglas, S. D.,Shanahan, F.,O'Connell, J. (2002) 'Nested RT-PCR. Sensitivity controls are essential to determine the biological significance of detected mRNA'. Methods Mol Biol, 193 :65-79 [Details]
(2002)'Type I insulin-like growth factor receptor expression on colorectal adenocarcinoma cell lines is decreased in response to the chemopreventive agent N-acetyl-l-cysteine'
Kelly, R. G.,Nally, K.,Shanahan, F.,O'Connell, J. (2002) 'Type I insulin-like growth factor receptor expression on colorectal adenocarcinoma cell lines is decreased in response to the chemopreventive agent N-acetyl-l-cysteine'. Ann N Y Acad Sci, 973 :555-8 [Details]
(2002)'RT-PCR for the assessment of genetically heterogenous populations of the hepatitis C virus'
Mullan, B.,Fanning, L. J.,Shanahan, F.,Sullivan, D. G. (2002) 'RT-PCR for the assessment of genetically heterogenous populations of the hepatitis C virus'. Methods Mol Biol, 193 :171-88 [Details]
(2002)'Sulfate-reducing bacteria colonize pouches formed for ulcerative colitis but not for familial adenomatous polyposis'
Duffy, M.,O'Mahony, L.,Coffey, J. C.,Collins, J. K.,Shanahan, F.,Redmond, H. P.,Kirwan, W. O.; (2002) 'Sulfate-reducing bacteria colonize pouches formed for ulcerative colitis but not for familial adenomatous polyposis'. Diseases of the Colon & Rectum, 45 (33):384-388384 Globe icon [Details]
(2002)'Crohn's disease'
Shanahan, F. (2002) 'Crohn's disease'. Lancet, 359 (9300):62-69 [Details]
(2002)'The host-microbe interface within the gut'
Shanahan, F. (2002) 'The host-microbe interface within the gut'. Best Practice & Research in Clinical Gastroenterology, 16 (6):915-931 [Details]
(2002)'Coeliac disease and autoimmune Addison's disease: a clinical pitfall'
O'Leary, C.,Walsh, C. H.,Wieneke, P.,O'Regan, P.,Buckley, B.,O'Halloran, D. J.,Ferriss, J. B.,Quigley, E. M.,Annis, P.,Shanahan, F.,Cronin, C. C. (2002) 'Coeliac disease and autoimmune Addison's disease: a clinical pitfall'. Qjm, 95 (22):79-82 [Details]
(2002)'Celiac disease and irritable bowel-type symptoms'
O'Leary, C.,Wieneke, P.,Buckley, S.,O'Regan, P.,Cronin, C. C.,Quigley, E. M.,Shanahan, F. (2002) 'Celiac disease and irritable bowel-type symptoms'. Am J Gastroenterol, 97 (66):1463-7 [Details]
(2002)'Food allergies'
O'Leary, P. F.,Shanahan, F. (2002) 'Food allergies'. Curr Gastroenterol Rep, 4 (55):373-82 [Details]
(2002)'Mycobacterium paratuberculosis detected by nested PCR in intestinal granulomas isolated by LCM in cases of Crohn's disease'
Ryan, P.,Aarons, S.,Bennett, M. W.,Lee, G.,O'Sullivan, G. C.,O'Connell, J.,Shanahan, F. (2002) 'Mycobacterium paratuberculosis detected by nested PCR in intestinal granulomas isolated by LCM in cases of Crohn's disease'. Methods Mol Biol, 193 :205-11 [Details]
(2002)'Viral discrimination and subversion of host defense at the epithelial gateway'
Shanahan, F. (2002) 'Viral discrimination and subversion of host defense at the epithelial gateway'. Gastroenterology, 123 (33):947-8 [Details]
(2002)'PCR detection of Mycobacterium paratuberculosis in Crohn's disease granulomas isolated by laser capture microdissection'
Ryan, P.,Bennett, M. W.,Aarons, S.,Lee, G.,Collins, J. K.,O'Sullivan, G. C.,O'Connell, J.,Shanahan, F. (2002) 'PCR detection of Mycobacterium paratuberculosis in Crohn's disease granulomas isolated by laser capture microdissection'. Gut, 51 (55):665-670665 Globe icon [Details]
(2002)'Probiotics and inflammatory bowel disease: from fads and fantasy to facts and future'
Shanahan, F. (2002) 'Probiotics and inflammatory bowel disease: from fads and fantasy to facts and future'. British Journal of Nutrition, 88 Globe icon [Details]
(2002)'Soluble interleukin 2 receptor levels in families of people with schizophrenia'
Gaughran, F.,O'Neill, E.,Sham, P.,Daly, R. J.,Shanahan, F. (2002) 'Soluble interleukin 2 receptor levels in families of people with schizophrenia'. Schizophr Res, 56 (33):235-239235 Globe icon [Details]
(2002)'Investigation of the genetic influence of the OPG, VDR (Fok1), and COLIA1 Sp1 polymorphisms on BMD in the Irish population'
Wynne, F.,Drummond, F.,O'Sullivan, K.,Daly, M.,Shanahan, F.,Molloy, M. G.,Quane, K. A. (2002) 'Investigation of the genetic influence of the OPG, VDR (Fok1), and COLIA1 Sp1 polymorphisms on BMD in the Irish population'. Calcif Tissue Int, 71 (11):26-3526 Globe icon [Details]
(2001)'Tumour necrosis factor 5' promoter single nucleotide polymorphisms influence susceptibility to rheumatoid arthritis (RA) in immunogenetically defined multiplex RA families'
Waldron-Lynch, F.,Adams, C.,Amos, C.,Zhu, D. K.,McDermott, M. F.,Shanahan, F.,Molloy, M. G.,O'Gara, F. (2001) 'Tumour necrosis factor 5' promoter single nucleotide polymorphisms influence susceptibility to rheumatoid arthritis (RA) in immunogenetically defined multiplex RA families'. Genes Immun, 2 (22):82-7 [Details]
(2001)'Immune privilege or inflammation? Insights into the Fas ligand enigma'
O'Connell, J.,Houston, A.,Bennett, M. W.,O'Sullivan, G. C.,Shanahan, F. (2001) 'Immune privilege or inflammation? Insights into the Fas ligand enigma'. Nat Med, 7 (33):271-4 [Details]
(2001)'p53 at the crossroads of colitis and cancer'
O'Riordan, A.,Shanahan, F. (2001) 'p53 at the crossroads of colitis and cancer'. Gastroenterology, 120 (77):1877-8 [Details]
(2001)'Mutant salmonella as vectors for gene therapy'
O'Sullivan, G. C.,Aarons, S. J.,Shanahan, F. (2001) 'Mutant salmonella as vectors for gene therapy'. Gastroenterology, 121 (11):224-6 [Details]
(2001)'Turbo probiotics for IBD'
Shanahan, F. (2001) 'Turbo probiotics for IBD'. Gastroenterology, 120 (55):1297-8 [Details]
(2001)'Inflammatory bowel disease: immunodiagnostics, immunotherapeutics, and ecotherapeutics'
Shanahan, F. (2001) 'Inflammatory bowel disease: immunodiagnostics, immunotherapeutics, and ecotherapeutics'. Gastroenterology, 120 (33):622-35 [Details]
(2001)'Tissue viral load variability in chronic hepatitis C'
Fanning, L.,Loane, J.,Kenny-Walsh, E.,Sheehan, M.,Whelton, M.,Kirwan, W.,Collins, J. K.,Shanahan, F. (2001) 'Tissue viral load variability in chronic hepatitis C'. 96 (1212):3384-33893384 Globe icon [Details]
(2001)'Soluble interleukin 2 receptor levels in acute and stable schizophrenia'
Gaughran, F.,O'Neill, E.,Sham, P.,Daly, R. J.,Shanahan, F. (2001) 'Soluble interleukin 2 receptor levels in acute and stable schizophrenia'. Schizophr Res, 52 (1-21-2):143-144143 Globe icon [Details]
(2001)'Anemia in patients with chronic inflammatory bowel disease'
Cronin, C. C.,Shanahan, F. (2001) 'Anemia in patients with chronic inflammatory bowel disease'. 96 (88):2296-22982296 Globe icon [Details]
(2001)'Fas ligand upregulation is an early event in colonic carcinogenesis'
Bennett, M. W.,O'Connell, J.,Houston, A.,Kelly, J.,O'Sullivan, G. C.,Collins, J. K.,Shanahan, F. (2001) 'Fas ligand upregulation is an early event in colonic carcinogenesis'. J Clin Pathol, 54 (88):598-604598 Globe icon [Details]
(2001)'Probiotic impact on microbial flora, inflammation and tumour development in IL-10 knockout mice'
O'Mahony, L.,Feeney, M.,O'Halloran, S.,Murphy, L.,Kiely, B.,Fitzgibbon, J.,Lee, G.,O'Sullivan, G.,Shanahan, F.,Collins, J. K. (2001) 'Probiotic impact on microbial flora, inflammation and tumour development in IL-10 knockout mice'. Aliment Pharmacol Ther, 15 (88):1219-12251219 Globe icon [Details]
(2001)'Upregulation of Fas-Fas-L (CD95/CD95L)-mediated epithelial apoptosis--a putative role in pouchitis?'
Coffey, J. C.,Bennett, M. W.,Wang, J. H.,O'Connell, J.,Neary, P.,Shanahan, F.,Redmond, H. P.,Kirwan, W. O. (2001) 'Upregulation of Fas-Fas-L (CD95/CD95L)-mediated epithelial apoptosis--a putative role in pouchitis?'. J Surg Res, 98 (11):27-32 [Details]
(2001)'HLA class II genes determine the natural variance of hepatitis C viral load'
Fanning, L. J.,Levis, J.,Kenny-Walsh, E.,Whelton, M.,O'Sullivan, K.,Shanahan, F. (2001) 'HLA class II genes determine the natural variance of hepatitis C viral load'. Hepatology, 33 (11):224-30 [Details]
(2001)'Why is celiac disease so common in Ireland?'
Cronin, C. C.,Shanahan, F. (2001) 'Why is celiac disease so common in Ireland?'. Perspect Biol Med, 44 (33):342-352342 Globe icon [Details]
(2001)'Constitutive ERK1/2 activation in esophagogastric rib bone marrow micrometastatic cells is MEK-independent'
Barry, O. P.,Mullan, B.,Sheehan, D.,Kazanietz, M. G.,Shanahan, F.,Collins, J. K.,O'Sullivan, G. C. (2001) 'Constitutive ERK1/2 activation in esophagogastric rib bone marrow micrometastatic cells is MEK-independent'. 276 (1818):15537-1554615537 Globe icon [Details]
(2001)'Probiotics in inflamatory bowel disease'
Shanahan, F. (2001) 'Probiotics in inflamatory bowel disease'. Gut, 48 (55):609-609609 Globe icon [Details]
(2001)'Inferred hepatitis C virus quasispecies diversity is influenced by choice of DNA polymerase in reverse transcriptase-polymerase chain reactions'
Mullan, B.,Kenny-Walsh, E.,Collins, J. K.,Shanahan, F.,Fanning, L. J. (2001) 'Inferred hepatitis C virus quasispecies diversity is influenced by choice of DNA polymerase in reverse transcriptase-polymerase chain reactions'. Anal Biochem, 289 (22):137-146137 Globe icon [Details]
(2001)'In vitro selection criteria for probiotic bacteria of human origin: correlation with in vivo findings'
Dunne, C.,O'Mahony, L.,Murphy, L.,Thornton, G.,Morrissey, D.,O'Halloran, S.,Feeney, M.,Flynn, S.,Fitzgerald, G.,Daly, C.,Kiely, B.,O 'Sullivan, G. C.,Shanahan, F.,Collins, J. K. (2001) 'In vitro selection criteria for probiotic bacteria of human origin: correlation with in vivo findings'. 73 (22) Globe icon [Details]
(2001)'Strategy for the maximization of clinically relevant information from hepatitis C virus, RT-PCR quantification'
Levis, J.,Kenny-Walsh, E.,O'Sullivan, K.,Horgan, M.,Whelton, M.,Shanahan, F.,Fanning, L. (2001) 'Strategy for the maximization of clinically relevant information from hepatitis C virus, RT-PCR quantification'. 20 (33):163-171163 Globe icon [Details]
(2001)'Relation between colitis and colon cancer'
Shanahan, F. (2001) 'Relation between colitis and colon cancer'. Lancet, 357 (92529252):246-247246 Globe icon [Details]
(2000)'Helicobacter pylori modulates lymphoepithelial cell interactions leading to epithelial cell damage through Fas/Fas ligand interactions'
Wang, J.,Fan, X.,Lindholm, C.,Bennett, M.,O'Connoll, J.,Shanahan, F.,Brooks, E. G.,Reyes, V. E.,Ernst, P. B. (2000) 'Helicobacter pylori modulates lymphoepithelial cell interactions leading to epithelial cell damage through Fas/Fas ligand interactions'. Infect Immun, 68 (77):4303-11 [Details]
(2000)'Immunological and genetic links in Crohn's disease'
Shanahan, F. (2000) 'Immunological and genetic links in Crohn's disease'. Gut, 46 (11):6-76 Globe icon [Details]
(2000)'The inflammatory response within Dukes' B colorectal cancers: implications for progression of micrometastases and patient survival'
Murphy, J.,O'Sullivan, G. C.,Lee, G.,Madden, M.,Shanahan, F.,Collins, J. K.,Talbot, I. C. (2000) 'The inflammatory response within Dukes' B colorectal cancers: implications for progression of micrometastases and patient survival'. Am J Gastroenterol, 95 (1212):3607-14 [Details]
(2000)'Esophagogastric cancer--time to change the paradigm'
O'Sullivan, G. C.,Shanahan, F. (2000) 'Esophagogastric cancer--time to change the paradigm'. Am J Gastroenterol, 95 (99):2153-4 [Details]
(2000)'Immunology. Therapeutic manipulation of gut flora'
Shanahan, F. (2000) 'Immunology. Therapeutic manipulation of gut flora'. Science, 289 (54835483):1311-2 [Details]
(2000)'Anti-TNF therapy for Crohn's disease: a perspective (infliximab is not the drug we have been waiting for)'
Shanahan, F. (2000) 'Anti-TNF therapy for Crohn's disease: a perspective (infliximab is not the drug we have been waiting for)'. Inflamm Bowel Dis, 6 (22):137-9 [Details]
(2000)'Probiotics and inflammatory bowel disease: is there a scientific rationale?'
Shanahan, F. (2000) 'Probiotics and inflammatory bowel disease: is there a scientific rationale?'. Inflamm Bowel Dis, 6 (22):107-15 [Details]
(2000)'Nutrient tasting and signaling mechanisms in the gut V. Mechanisms of immunologic sensation of intestinal contents'
Shanahan, F. (2000) 'Nutrient tasting and signaling mechanisms in the gut V. Mechanisms of immunologic sensation of intestinal contents'. Am J Physiol Gastrointest Liver Physiol, 278 (22) [Details]
(2000)'Functional foods and probiotics: time for gastroenterologists to embrace the concept'
Shanahan, F.,McCarthy, J. (2000) 'Functional foods and probiotics: time for gastroenterologists to embrace the concept'. Curr Gastroenterol Rep, 2 (55):345-6 [Details]
(2000)'Turning on T-cell death and turning off Crohn's disease'
Shanahan, F.,Nally, K.,O'Sullivan, G. C. (2000) 'Turning on T-cell death and turning off Crohn's disease'. Gastroenterology, 119 (44):1166-8 [Details]
(2000)'Gene therapy for food allergy'
Shanahan, F.,O'Sullivan, G. C. (2000) 'Gene therapy for food allergy'. Gastroenterology, 119 (11):269-70 [Details]
(2000)'How do intestinal T cells sense the dietary and microbial environment?'
Shanahan, F.,O'Sullivan, G. C. (2000) 'How do intestinal T cells sense the dietary and microbial environment?'. Gastroenterology, 118 (22):444-6 [Details]
(2000)'Natural fluctuations of hepatitis C viral load in a homogeneous patient population: a prospective study'
Fanning, L.,Kenny-Walsh, E.,Levis, J.,Choudhury, K. R.,Cannon, B.,Sheehan, M.,Whelton, M.,Shanahan, F. (2000) 'Natural fluctuations of hepatitis C viral load in a homogeneous patient population: a prospective study'. Hepatology, 31 (11):225-9225 Globe icon [Details]
(2000)'Viral clearance in hepatitis C (1b) infection: relationship with human leukocyte antigen class II in a homogeneous population'
Fanning, L. J.,Levis, J.,Kenny-Walsh, E.,Wynne, F.,Whelton, M.,Shanahan, F. (2000) 'Viral clearance in hepatitis C (1b) infection: relationship with human leukocyte antigen class II in a homogeneous population'. Hepatology, 31 (66):1334-7 [Details]
(2000)'Biological behaviour and clinical implications of micrometastases'
Kell, M. R.,Winter, D. C.,O'Sullivan, G. C.,Shanahan, F.,Redmond, H. P.; (2000) 'Biological behaviour and clinical implications of micrometastases'. British Journal of Surgery, 87 (1212):1629-16391629 Globe icon [Details]
(2000)'Interferon-gamma sensitizes colonic epithelial cell lines to physiological and therapeutic inducers of colonocyte apoptosis'
O'Connell, J.,Bennett, M. W.,Nally, K.,O'Sullivan, G. C.,Collins, J. K.,Shanahan, F. (2000) 'Interferon-gamma sensitizes colonic epithelial cell lines to physiological and therapeutic inducers of colonocyte apoptosis'. J Cell Physiol, 185 (33):331-338331 Globe icon [Details]
(2000)'Bone-marrow micrometastases in patients with brain metastases from epithelial cell tumours'
Maguire, D.,O'Sullivan, G. C.,McNamara, B.,Collins, J. K.,Shanahan, F. (2000) 'Bone-marrow micrometastases in patients with brain metastases from epithelial cell tumours'. Qjm-Monthly Journal of the Association of Physicians, 93 (99):611-615611 Globe icon [Details]
(2000)'Pregnancy and pregnancy outcome in hepatitis C type 1b'
Jabeen, T.,Cannon, B.,Hogan, J.,Crowley, M.,Devereux, C.,Fanning, L.,Kenny-Walsh, E.,Shanahan, F.,Whelton, M. J. (2000) 'Pregnancy and pregnancy outcome in hepatitis C type 1b'. Qjm-an International Journal of Medicine, 93 (99):597-601597 Globe icon [Details]
(2000)'Neurokinin-1 receptor expression in inflammatory bowel disease: molecular quantitation and localisation'
Goode, T.,O'Connell, J.,Anton, P.,Wong, H.,Reeve, J.,O'Sullivan, G. C.,Collins, J. K.,Shanahan, F. (2000) 'Neurokinin-1 receptor expression in inflammatory bowel disease: molecular quantitation and localisation'. Gut, 47 (33):387-396387 Globe icon [Details]
(2000)'Bone marrow micrometastases and gastrointestinal cancer detection and significance'
Maguire, D.,O'Sullivan, G. C.,Collins, J. K.,Morgan, J.,Shanahan, F. (2000) 'Bone marrow micrometastases and gastrointestinal cancer detection and significance'. 95 (77):1644-16511644 Globe icon [Details]
(2000)'The stress response and the hypothalamic-pituitary-adrenal axis: from molecule to melancholia'
O'Connor, T. M.,O'Halloran, D. J.,Shanahan, F. (2000) 'The stress response and the hypothalamic-pituitary-adrenal axis: from molecule to melancholia'. Qjm-Monthly Journal of the Association of Physicians, 93 (66):323-333323 Globe icon [Details]
(2000)'Differential expression of neurokinin-1 receptor by human mucosal and peripheral lymphoid cells'
Goode, T.,O'Connell, J.,Ho, W. Z.,O'Sullivan, G. C.,Collins, J. K.,Douglas, S. D.,Shanahan, F. (2000) 'Differential expression of neurokinin-1 receptor by human mucosal and peripheral lymphoid cells'. Clin Diagn Lab Immunol, 7 (33):371-376371 Globe icon [Details]
(2000)'Colorectal cancer: still a major killer despite progress on many fronts'
Shanahan, F.,O'Sullivan, G. C.,O'Leary, C. (2000) 'Colorectal cancer: still a major killer despite progress on many fronts'. Qjm-Monthly Journal of the Association of Physicians, 93 (33):131-134131 Globe icon [Details]
(2000)'Altered mechanisms of apoptosis in colon cancer: Fas resistance and counterattack in the tumor-immune conflict'
O'Connell, J.,Bennett, M. W.,Nally, K.,Houston, A.,O'Sullivan, G. C.,Shanahan, F. (2000) 'Altered mechanisms of apoptosis in colon cancer: Fas resistance and counterattack in the tumor-immune conflict'. 910 :178-195178 Globe icon [Details]
(2000)'BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines'
Wong, A. K.,Shanahan, F.,Chen, Y.,Lian, L.,Ha, P.,Hendricks, K.,Ghaffari, S.,Iliev, D.,Penn, B.,Woodland, A. M.,Smith, R.,Salada, G.,Carillo, A.,Laity, K.,Gupte, J.,Swedlund, B.,Tavtigian, S. V.,Teng, D. H.,Lees, E. (2000) 'BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines'. Cancer Res, 60 (2121):6171-7 [Details]
(1999)'Fas counter-attack--the best form of tumor defense?'
O'Connell, J.,Bennett, M. W.,O'Sullivan, G. C.,Collins, J. K.,Shanahan, F. (1999) 'Fas counter-attack--the best form of tumor defense?'. Nat Med, 5 (33):267-8 [Details]
(1999)'Fas ligand and Fas receptor are coexpressed in normal human esophageal epithelium: a potential mechanism of apoptotic epithelial turnover'
Bennett, M. W.,O'Connell, J.,O'Sullivan, G. C.,Roche, D.,Brady, C.,Collins, J. K.,Shanahan, F. (1999) 'Fas ligand and Fas receptor are coexpressed in normal human esophageal epithelium: a potential mechanism of apoptotic epithelial turnover'. 12 (22):90-9890 Globe icon [Details]
(1999)'Micrometastases in esophagogastric cancer: high detection rate in resected rib segments'
O'Sullivan G, C.,Sheehan, D.,Clarke, A.,Stuart, R.,Kelly, J.,Kiely, M. D.,Walsh, T.,Collins, J. K.,Shanahan, F. (1999) 'Micrometastases in esophagogastric cancer: high detection rate in resected rib segments'. Gastroenterology, 116 (33):543-8 [Details]
(1999)'Escape from the Smad world by colon cancer'
O'Sullivan, G. C.,Shanahan, F. (1999) 'Escape from the Smad world by colon cancer'. Gastroenterology, 116 (66):1496-7 [Details]
(1999)'Setback for systemic therapy of esophageal cancer: right concept, disappointing result'
O'Sullivan, G. C.,Shanahan, F.,Talwalkar, J.,Van Dam, J. (1999) 'Setback for systemic therapy of esophageal cancer: right concept, disappointing result'. Gastroenterology, 117 (44):1020-2 [Details]
(1999)'Brain-gut axis and mucosal immunity: a perspective on mucosal psychoneuroimmunology'
Shanahan, F. (1999) 'Brain-gut axis and mucosal immunity: a perspective on mucosal psychoneuroimmunology'. Semin Gastrointest Dis, 10 (11):8-13 [Details]
(1999)'Neurokinin antagonism and chemotherapy-induced emesis'
Shanahan, F.,O'Sullivan, G. C. (1999) 'Neurokinin antagonism and chemotherapy-induced emesis'. Am J Gastroenterol, 94 (1111):3368-9 [Details]
(1999)'Glial cells, mucosal integrity, and inflammatory bowel disease'
Shanahan, F.,Sullivan, G. C. (1999) 'Glial cells, mucosal integrity, and inflammatory bowel disease'. Gastroenterology, 116 (22):493-4 [Details]
(1999)'Genetic analysis of the 3' untranslated region of the tumour necrosis factor shows a highly conserved region in rheumatoid arthritis affected and unaffected subjects'
Waldron-Lynch, F.,Adams, C.,Shanahan, F.,Molloy, M. G.,O'Gara, F. (1999) 'Genetic analysis of the 3' untranslated region of the tumour necrosis factor shows a highly conserved region in rheumatoid arthritis affected and unaffected subjects'. J Med Genet, 36 (33):214-6 [Details]
(1999)'Expression of Fas ligand by human gastric adenocarcinomas: a potential mechanism of immune escape in stomach cancer'
Bennett, M. W.,O'Connell, J.,O'Sullivan G, C.,Roche, D.,Brady, C.,Kelly, J.,Collins, J. K.,Shanahan, F. (1999) 'Expression of Fas ligand by human gastric adenocarcinomas: a potential mechanism of immune escape in stomach cancer'. Gut, 44 (22):156-62 [Details]
(1999)'Probiotics: from myth to reality. Demonstration of functionality in animal models of disease and in human clinical trials'
Dunne, C.,Murphy, L.,Flynn, S.,O'Mahony, L.,O'Halloran, S.,Feeney, M.,Morrissey, D.,Thornton, G.,Fitzgerald, G.,Daly, C.,Kiely, B.,Quigley, E. M.,O'Sullivan, G. C.,Shanahan, F.,Collins, J. K. (1999) 'Probiotics: from myth to reality. Demonstration of functionality in animal models of disease and in human clinical trials'. Antonie Van Leeuwenhoek, 76 (1-41-4):279-92 [Details]
(1999)'Viral load and clinicopathological features of chronic hepatitis C (1b) in a homogeneous patient population'
Fanning, L.,Kenny, E.,Sheehan, M.,Cannon, B.,Whelton, M.,O'Connell, J.,Collins, J. K.,Shanahan, F. (1999) 'Viral load and clinicopathological features of chronic hepatitis C (1b) in a homogeneous patient population'. Hepatology, 29 (33):904-7 [Details]
(1999)'Regulation of G1/S transition in mammalian cells'
Guevara, C.,Korver, W.,Mahony, D.,Parry, D.,Seghezzi, W.,Shanahan, F.,Lees, E. (1999) 'Regulation of G1/S transition in mammalian cells'. Kidney Int, 56 (44):1181-92 [Details]
(1999)'Type 1 diabetes mellitus, coeliac disease, and lymphoma: a report of four cases'
O'Connor, T. M.,Cronin, C. C.,Loane, J. F.,O'Meara, N. M.,Firth, R. G.,Shanahan, F.,O'Halloran, D. J. (1999) 'Type 1 diabetes mellitus, coeliac disease, and lymphoma: a report of four cases'. Diabetic Medicine, 16 (77):614-617614 Globe icon [Details]
(1999)'An international survey of the use and attitudes regarding alternative medicine by patients with inflammatory bowel disease'
Rawsthorne, P.,Shanahan, F.,Cronin, N. C.,Anton, P. A.,Lofberg, R.,Bohman, L.,Bernstein, C. N. (1999) 'An international survey of the use and attitudes regarding alternative medicine by patients with inflammatory bowel disease'. 94 (55):1298-13031298 Globe icon [Details]
(1999)'Thrombosis, factor V Leiden, and inflammatory bowel disease'
Shanahan, F. (1999) 'Thrombosis, factor V Leiden, and inflammatory bowel disease'. Gastroenterology, 116 (33):778-779778 Globe icon [Details]
(1999)'Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrest'
Shanahan, F.,Seghezzi, W.,Parry, D.,Mahony, D.,Lees, E. (1999) 'Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrest'. Mol Cell Biol, 19 (22):1460-14691460 Globe icon [Details]
(1999)'Invasion by esophageal cancer cells: functional contribution of the urokinase plasminogen activation system, and inhibition by antisense oligonucleotides to urokinase or urokinase receptor'
Morrissey, D.,O'Connell, J.,Lynch, D.,O'Sullivan, G. C.,Shanahan, F.,Collins, J. K. (1999) 'Invasion by esophageal cancer cells: functional contribution of the urokinase plasminogen activation system, and inhibition by antisense oligonucleotides to urokinase or urokinase receptor'. Clin Exp Metastasis, 17 (11):77-8577 Globe icon [Details]
(1999)'Intestinal lymphoepithelial communication'
Shanahan, F. (1999) 'Intestinal lymphoepithelial communication'. 473 :1-91 Globe icon [Details]
(1999)'The Fas counterattack: cancer as a site of immune privilege'
O'Connell, J.,Bennett, M. W.,O'Sullivan, G. C.,Collins, J. K.,Shanahan, F. (1999) 'The Fas counterattack: cancer as a site of immune privilege'. Immunol Today, 20 (11):46-5246 Globe icon [Details]
(1999)'Resistance to Fas (APO-1/CD95)-mediated apoptosis and expression of Fas ligand in esophageal cancer: the Fas counterattack'
O'Connell, J.,Bennett, M. W.,O'Sullivan, G. C.,Collins, J. K.,Shanahan, F. (1999) 'Resistance to Fas (APO-1/CD95)-mediated apoptosis and expression of Fas ligand in esophageal cancer: the Fas counterattack'. 12 (22):83-8983 Globe icon [Details]
(1999)'Expression of Fas (CD95/APO-1) ligand by human breast cancers: significance for tumor immune privilege'
O'Connell, J.,Bennett, M. W.,O'Sullivan, G. C.,O'Callaghan, J.,Collins, J. K.,Shanahan, F. (1999) 'Expression of Fas (CD95/APO-1) ligand by human breast cancers: significance for tumor immune privilege'. Clin Diagn Lab Immunol, 6 (44):457-63 [Details]
(1998)'Fas ligand expression in primary colon adenocarcinomas: evidence that the Fas counterattack is a prevalent mechanism of immune evasion in human colon cancer'
O'Connell, J.,Bennett, M. W.,O'Sullivan, G. C.,Roche, D.,Kelly, J.,Collins, J. K.,Shanahan, F. (1998) 'Fas ligand expression in primary colon adenocarcinomas: evidence that the Fas counterattack is a prevalent mechanism of immune evasion in human colon cancer'. J Pathol, 186 (33):240-6 [Details]
(1998)'Modelling the major histocompatibility complex susceptibility to RA using the MASC method'
Genin, E.,Babron, M. C.,McDermott, M. F.,Mulcahy, B.,Waldron-Lynch, F.,Adams, C.,Clegg, D. O.,Ward, R. H.,Shanahan, F.,Molloy, M. G.,O'Gara, F.,Clerget-Darpoux, F. (1998) 'Modelling the major histocompatibility complex susceptibility to RA using the MASC method'. Genet Epidemiol, 15 (44):419-430419 Globe icon [Details]
(1998)'Enteropathogenic E. coli: intimacy redefined'
Shanahan, F.,O'Sullivan, G. C. (1998) 'Enteropathogenic E. coli: intimacy redefined'. Gastroenterology, 115 (11):233-4 [Details]
(1998)'Genes, bacteria, and T cells: ingredients for inflammatory bowel disease'
Shanahan, F.,O'Sullivan, G. C.,Collins, J. K. (1998) 'Genes, bacteria, and T cells: ingredients for inflammatory bowel disease'. Gastroenterology, 115 (66):1595-6 [Details]
(1998)'Immuno-epithelial interactions: cytokine modulation of normal rabbit colonocyte function'
Vidrich, A.,Anton, P. A.,Shanahan, F. (1998) 'Immuno-epithelial interactions: cytokine modulation of normal rabbit colonocyte function'. In Vitro Cell Dev Biol Anim, 34 (1010):743-6 [Details]
(1998)'Neuroimmunomodulation in inflammatory bowel disease. How far from bench to bedside?'
Anton, P. A.,Shanahan, F. (1998) 'Neuroimmunomodulation in inflammatory bowel disease. How far from bench to bedside?'. Ann N Y Acad Sci, 840 :723-34 [Details]
(1998)'The Fas counterattack in vivo: apoptotic depletion of tumor-infiltrating lymphocytes associated with Fas ligand expression by human esophageal carcinoma'
Bennett, M. W.,O'Connell, J.,O'Sullivan, G. C.,Brady, C.,Roche, D.,Collins, J. K.,Shanahan, F. (1998) 'The Fas counterattack in vivo: apoptotic depletion of tumor-infiltrating lymphocytes associated with Fas ligand expression by human esophageal carcinoma'. J Immunol, 160 (1111):5669-75 [Details]
(1998)'A significant step in the celiac puzzle'
Cronin, C.,Shanahan, F. (1998) 'A significant step in the celiac puzzle'. Gastroenterology, 114 (66):1339-41 [Details]
(1998)'Immunological tests to monitor inflammatory bowel disease--have they delivered yet?'
Cronin, C. C.,Shanahan, F. (1998) 'Immunological tests to monitor inflammatory bowel disease--have they delivered yet?'. Am J Gastroenterol, 93 (33):295-7 [Details]
(1998)'Increased soluble interleukin 2 receptor levels in schizophrenia'
Gaughran, F.,O'Neill, E.,Cole, M.,Collins, K.,Daly, R. J.,Shanahan, F. (1998) 'Increased soluble interleukin 2 receptor levels in schizophrenia'. Schizophr Res, 29 (33):263-7 [Details]
(1998)'Substance P (neurokinin-1) receptor is a marker of human mucosal but not peripheral mononuclear cells: molecular quantitation and localization'
Goode, T.,O'Connell, J.,Sternini, C.,Anton, P.,Wong, H.,O'Sullivan, G. C.,Collins, J. K.,Shanahan, F. (1998) 'Substance P (neurokinin-1) receptor is a marker of human mucosal but not peripheral mononuclear cells: molecular quantitation and localization'. J Immunol, 161 (55):2232-40 [Details]
(1998)'Cyclin E associates with components of the pre-mRNA splicing machinery in mammalian cells'
Seghezzi, W.,Chua, K.,Shanahan, F.,Gozani, O.,Reed, R.,Lees, E. (1998) 'Cyclin E associates with components of the pre-mRNA splicing machinery in mammalian cells'. Mol Cell Biol, 18 (88):4526-45364526 Globe icon [Details]
(1998)'Intestinal graft-versus-host disease'
Shanahan, F. (1998) 'Intestinal graft-versus-host disease'. Gastroenterology, 115 (11):220-222220 Globe icon [Details]
(1998)'Enteric neuropathophysiology and inflammatory bowel disease'
Shanahan, F. (1998) 'Enteric neuropathophysiology and inflammatory bowel disease'. Neurogastroenterology and Motility, 10 (33):185-187185 Globe icon [Details]
(1998)'Coeliac disease and epilepsy'
Cronin, C. C.,Jackson, L. M.,Feighery, C.,Shanahan, F.,Abuzakouk, M.,Ryder, D. Q.,Whelton, M.,Callaghan, N. (1998) 'Coeliac disease and epilepsy'. Qjm-an International Journal of Medicine, 91 (44):303-308303 Globe icon [Details]
(1998)'Mucosal subepithelial binding sites for the bacterial chemotactic peptide, formyl-methionyl-leucyl-phenylalanine (FMLP)'
Anton, P.,O'Connell, J.,O'Connell, D.,Whitaker, L.,O'Sullivan, G. C.,Collins, J. K.,Shanahan, F. (1998) 'Mucosal subepithelial binding sites for the bacterial chemotactic peptide, formyl-methionyl-leucyl-phenylalanine (FMLP)'. Gut, 42 (33):374-379374 Globe icon [Details]
(1998)'Quantitative measurement of mRNA expression by competitive RT-PCR'
O'Connell, J.,Goode, T.,Shanahan, F. (1998) 'Quantitative measurement of mRNA expression by competitive RT-PCR'. Methods Mol Biol, 92 :183-93 [Details]
(1997)'Mucosal substance P receptor expression in HIV infection and inflammatory bowel disease'
McGowan, I. M.,Fairhurst, R. M.,Shanahan, F.,Anton, P. A. (1997) 'Mucosal substance P receptor expression in HIV infection and inflammatory bowel disease'. Neuroimmunomodulation, 4 (22):70-6 [Details]
(1997)'Addison disease in patients treated with glucocorticoid therapy'
Cronin, C. C.,Callaghan, N.,Kearney, P. J.,Murnaghan, D. J.,Shanahan, F. (1997) 'Addison disease in patients treated with glucocorticoid therapy'. Arch Intern Med, 157 (44):456-458456 Globe icon [Details]
(1997)'Micrometastases: marker of metastatic potential or evidence of residual disease?'
O'Sullivan, G. C.,Collins, J. K.,Kelly, J.,Morgan, J.,Madden, M.,Shanahan, F. (1997) 'Micrometastases: marker of metastatic potential or evidence of residual disease?'. Gut, 40 (44):512-5 [Details]
(1997)'Designer drugs for inflammatory bowel disease'
Shanahan, F. (1997) 'Designer drugs for inflammatory bowel disease'. Gastroenterology, 112 (66):2153-4 [Details]
(1997)'Antibody 'markers' in Crohn's disease: opportunity or overstatement?'
Shanahan, F. (1997) 'Antibody 'markers' in Crohn's disease: opportunity or overstatement?'. Gut, 40 (44):557-8 [Details]
(1997)'A gut reaction: lymphoepithelial communication in the intestine'
Shanahan, F. (1997) 'A gut reaction: lymphoepithelial communication in the intestine'. Science, 275 (53085308):1897-8 [Details]
(1997)'Confirmation of the Fas counterattack in host-tumor relations'
Shanahan, F.,O'Connell, J.,O'Sullivan, G. C. (1997) 'Confirmation of the Fas counterattack in host-tumor relations'. Gastroenterology, 113 (55):1804-6 [Details]
(1997)'Appendectomy, mucosal immunity, and colitis'
Shanahan, F.,O'Sullivan, G. C. (1997) 'Appendectomy, mucosal immunity, and colitis'. Gastroenterology, 112 (55):1766-7 [Details]
(1997)'Progress in treating esophageal adenocarcinoma'
Shanahan, F.,O'Sullivan, G. C. (1997) 'Progress in treating esophageal adenocarcinoma'. Gastroenterology, 112 (44):1417-8 [Details]
(1997)'Histological patchiness and sparing of the rectum in ulcerative colitis: refuting the dogma'
Bernstein, C. N.,Shanahan, F.,Weinstein, W. M. (1997) 'Histological patchiness and sparing of the rectum in ulcerative colitis: refuting the dogma'. J Clin Pathol, 50 (44):354-5 [Details]
(1997)'High prevalence of celiac disease among patients with insulin-dependent (type I) diabetes mellitus'
Cronin, C. C.,Feighery, A.,Ferriss, J. B.,Liddy, C.,Shanahan, F.,Feighery, C. (1997) 'High prevalence of celiac disease among patients with insulin-dependent (type I) diabetes mellitus'. Am J Gastroenterol, 92 (1212):2210-2 [Details]
(1997)'Innate resistance to Listeria monocytogenes in tumor-bearing mice'
Gahan, C. G.,Barrett, J. R.,O'Brien, M. G.,O'Sullivan, G. C.,Shanahan, F.,Collins, J. K. (1997) 'Innate resistance to Listeria monocytogenes in tumor-bearing mice'. J Leukoc Biol, 62 (66):726-32 [Details]
(1997)'Quantification of the placebo response in ulcerative colitis'
Ilnyckyj, A.,Shanahan, F.,Anton, P. A.,Cheang, M.,Bernstein, C. N. (1997) 'Quantification of the placebo response in ulcerative colitis'. Gastroenterology, 112 (66):1854-8 [Details]
(1997)'Thrombosis in inflammatory bowel disease: clinical setting, procoagulant profile and factor V Leiden'
Jackson, L. M.,O'Gorman, P. J.,O'Connell, J.,Cronin, C. C.,Cotter, K. P.,Shanahan, F. (1997) 'Thrombosis in inflammatory bowel disease: clinical setting, procoagulant profile and factor V Leiden'. Qjm, 90 (33):183-8 [Details]
(1997)'Insulin-dependent diabetes mellitus and coeliac disease'
Cronin, C. C.,Shanahan, F. (1997) 'Insulin-dependent diabetes mellitus and coeliac disease'. Lancet, 349 (90589058):1096-10971096 Globe icon [Details]
(1997)'The Fas counterattack: a molecular mechanism of tumor immune privilege'
O'Connell, J.,Bennett, M. W.,O'Sullivan, G. C.,Collins, J. K.,Shanahan, F. (1997) 'The Fas counterattack: a molecular mechanism of tumor immune privilege'. Mol Med, 3 (55):294-300 [Details]
(1996)'Genetic variability in the tumor necrosis factor-lymphotoxin region influences susceptibility to rheumatoid arthritis'
Mulcahy, B.,Waldron-Lynch, F.,McDermott, M. F.,Adams, C.,Amos, C. I.,Zhu, D. K.,Ward, R. H.,Clegg, D. O.,Shanahan, F.,Molloy, M. G.,O'Gara, F. (1996) 'Genetic variability in the tumor necrosis factor-lymphotoxin region influences susceptibility to rheumatoid arthritis'. Am J Hum Genet, 59 (33):676-83 [Details]
(1996)'The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand'
O'Connell, J.,O'Sullivan, G. C.,Collins, J. K.,Shanahan, F. (1996) 'The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand'. J Exp Med, 184 (33):1075-82 [Details]
(1996)'MALTectomy (appendectomy/tonsillectomy) does not influence the occurrence or mode of presentation of adult celiac disease'
O'Gorman, P.,Bennett, D.,Kavanagh, E.,Twohig, L. B.,O'Sullivan, G. C.,O'Regan, P.,Shanahan, F. (1996) 'MALTectomy (appendectomy/tonsillectomy) does not influence the occurrence or mode of presentation of adult celiac disease'. Am J Gastroenterol, 91 (44):723-5 [Details]
(1996)'Regional immunosuppression in esophageal squamous cancer: evidence from functional studies with matched lymph nodes'
O'Sullivan, G. C.,Corbett, A. R.,Shanahan, F.,Collins, J. K. (1996) 'Regional immunosuppression in esophageal squamous cancer: evidence from functional studies with matched lymph nodes'. J Immunol, 157 (1010):4717-20 [Details]
(1996)'Closing in on the genetics of Crohn's disease'
Shanahan, F. (1996) 'Closing in on the genetics of Crohn's disease'. Gastroenterology, 111 (55):1390-1 [Details]
(1996)'Cyclin C/CDK8 is a novel CTD kinase associated with RNA polymerase II'
Rickert, P.,Seghezzi, W.,Shanahan, F.,Cho, H.,Lees, E. (1996) 'Cyclin C/CDK8 is a novel CTD kinase associated with RNA polymerase II'. Oncogene, 12 (1212):2631-26402631 Globe icon [Details]
(1996)'A randomized, placebo-controlled trial of calcium supplementation for decreased bone density in corticosteroid-using patients with inflammatory bowel disease: a pilot study'
Bernstein, C. N.,Seeger, L. L.,Anton, P. A.,Artinian, L.,Geffrey, S.,Goodman, W.,Belin, T. R.,Shanahan, F. (1996) 'A randomized, placebo-controlled trial of calcium supplementation for decreased bone density in corticosteroid-using patients with inflammatory bowel disease: a pilot study'. Aliment Pharmacol Ther, 10 (55):777-86 [Details]
(1996)'Purine analogues and Crohn's disease: learning more about the long-term'
Bernstein, C. N.,Shanahan, F. (1996) 'Purine analogues and Crohn's disease: learning more about the long-term'. Gastroenterology, 111 (66):1774-6 [Details]
(1996)'Appropriateness of laboratory tests: requests for atypical pneumonia serology in a teaching hospital'
Jackson, L. M.,Shanahan, F.,Cryan, B.,Bredin, C. P.,Cronin, C. C. (1996) 'Appropriateness of laboratory tests: requests for atypical pneumonia serology in a teaching hospital'. Ir J Med Sci, 165 (22):93-4 [Details]
(1996)'Critical appraisal of enteral nutrition as primary therapy in adults with Crohn's disease'
Bernstein, C. N.,Shanahan, F. (1996) 'Critical appraisal of enteral nutrition as primary therapy in adults with Crohn's disease'. 91 (1010):2075-20792075 Globe icon [Details]
(1996)'Cadherins, inflammatory bowel disease, and neoplasia'
Shanahan, F. (1996) 'Cadherins, inflammatory bowel disease, and neoplasia'. Gastroenterology, 111 (11):261-2 [Details]
(1995)'Psychoneuroimmunology and suicidal behaviour'
Kelleher, M.,Shanahan, F. (1995) 'Psychoneuroimmunology and suicidal behaviour'. Ir Med J, 88 (11) [Details]
(1995)'Non-linkage of a T-cell receptor gamma chain microsatellite (D7S485) to rheumatoid arthritis in multiplex families'
McDermott, M.,Hsu, C.,Molloy, M. G.,Mulcahy, B.,Phelan, M.,Shanahan, F.,O'Gara, F.,Adams, C.,Rubin, L. A.,Clegg, D. O.,et al., (1995) 'Non-linkage of a T-cell receptor gamma chain microsatellite (D7S485) to rheumatoid arthritis in multiplex families'. J Autoimmun, 8 (11):131-8 [Details]
(1995)'A prospective comparison of laparoscopy and imaging in the staging of esophagogastric cancer before surgery'
O'Brien, M. G.,Fitzgerald, E. F.,Lee, G.,Crowley, M.,Shanahan, F.,O'Sullivan, G. C. (1995) 'A prospective comparison of laparoscopy and imaging in the staging of esophagogastric cancer before surgery'. Am J Gastroenterol, 90 (1212):2191-4 [Details]
(1995)'Micrometastases in bone marrow of patients undergoing curative surgery for gastrointestinal cancer'
O'Sullivan, G. C.,Collins, J. K.,O'Brien, F.,Crowley, B.,Murphy, K.,Lee, G.,Shanahan, F. (1995) 'Micrometastases in bone marrow of patients undergoing curative surgery for gastrointestinal cancer'. Gastroenterology, 109 (55):1535-40 [Details]
(1995)'Crohn's disease: to lump or to split?'
Shanahan, F. (1995) 'Crohn's disease: to lump or to split?'. Gastroenterology, 109 (66):2045-6 [Details]
(1995)'From basic advances to therapeutic strategies in ulcerative colitis'
Shanahan, F. (1995) 'From basic advances to therapeutic strategies in ulcerative colitis'. Qjm, 88 (99):599-602 [Details]
(1995)'Sarcoidosis, the pancreas, and diabetes mellitus'
Cronin, C. C.,Dinneen, S. F.,Mitchell, T. H.,Shanahan, F. L. (1995) 'Sarcoidosis, the pancreas, and diabetes mellitus'. Am J Gastroenterol, 90 (1111) [Details]
(1995)'Stem cell factor and intestinal lymphoepithelial communication'
Shanahan, F.,O'Sullivan, G. C. (1995) 'Stem cell factor and intestinal lymphoepithelial communication'. Gastroenterology, 109 (44):1397-8 [Details]
(1995)'Angiostatin: candidate for molecule of the year!'
Shanahan, F.,O'Sullivan, G. C. (1995) 'Angiostatin: candidate for molecule of the year!'. Gastroenterology, 108 (66):1946-8 [Details]
(1995)'Decreased bone density in inflammatory bowel disease is related to corticosteroid use and not disease diagnosis'
Bernstein, C. N.,Seeger, L. L.,Sayre, J. W.,Anton, P. A.,Artinian, L.,Shanahan, F. (1995) 'Decreased bone density in inflammatory bowel disease is related to corticosteroid use and not disease diagnosis'. J Bone Miner Res, 10 (22):250-6 [Details]
(1995)'Cyclosporine and inflammatory bowel disease: still more questions'
Bernstein, C. N.,Shanahan, F. (1995) 'Cyclosporine and inflammatory bowel disease: still more questions'. Gastroenterology, 108 (33):943-5 [Details]
(1995)'Patchiness of mucosal inflammation in treated ulcerative colitis: a prospective study'
Bernstein, C. N.,Shanahan, F.,Anton, P. A.,Weinstein, W. M. (1995) 'Patchiness of mucosal inflammation in treated ulcerative colitis: a prospective study'. Gastrointest Endosc, 42 (33):232-7 [Details]
(1995)'Physicians' perceptions of dysplasia and approaches to surveillance colonoscopy in ulcerative colitis'
Bernstein, C. N.,Weinstein, W. M.,Levine, D. S.,Shanahan, F. (1995) 'Physicians' perceptions of dysplasia and approaches to surveillance colonoscopy in ulcerative colitis'. Am J Gastroenterol, 90 (1212):2106-14 [Details]
(1995)'Discontent with dysplasia surveillance in ulcerative colitis'
Shanahan, F. (1995) 'Discontent with dysplasia surveillance in ulcerative colitis'. Inflamm Bowel Dis, 1 (11):80-3 [Details]
(1994)'Current concepts of the pathogenesis of inflammatory bowel disease'
Shanahan, F. (1994) 'Current concepts of the pathogenesis of inflammatory bowel disease'. Ir J Med Sci, 163 (1212):544-9 [Details]
(1994)'Neutrophil autoantibodies in inflammatory bowel disease: are they important?'
Shanahan, F. (1994) 'Neutrophil autoantibodies in inflammatory bowel disease: are they important?'. Gastroenterology, 107 (22):586-9 [Details]
(1994)'Safety of low-dose purine analogues in inflammatory bowel disease'
Shanahan, F.,Bernstein, C. N. (1994) 'Safety of low-dose purine analogues in inflammatory bowel disease'. Gastroenterology, 107 (66):1905-6 [Details]
(1994)'Reduced signal transduction through glucocorticoid receptor in Burkitt's lymphoma cell lines'
Sinclair, A. J.,Jacquemin, M. G.,Brooks, L.,Shanahan, F.,Brimmell, M.,Rowe, M.,Farrell, P. J. (1994) 'Reduced signal transduction through glucocorticoid receptor in Burkitt's lymphoma cell lines'. Virology, 199 (22):339-53 [Details]
(1994)'A mechanism for esophageal tumor-derived immunosuppression'
Shanahan, F. (1994) 'A mechanism for esophageal tumor-derived immunosuppression'. Gastroenterology, 106 (66):1717-8 [Details]
(1994)'Low-dose 6-mercaptopurine in inflammatory bowel disease is associated with minimal hematologic toxicity'
Bernstein, C. N.,Artinian, L.,Anton, P. A.,Shanahan, F. (1994) 'Low-dose 6-mercaptopurine in inflammatory bowel disease is associated with minimal hematologic toxicity'. Dig Dis Sci, 39 (88):1638-41 [Details]
(1994)'Epstein-Barr virus SM protein'
Cook, I. D.,Shanahan, F.,Farrell, P. J. (1994) 'Epstein-Barr virus SM protein'. Virology, 205 (11):217-27 [Details]
(1994)'Are we telling patients the truth about surveillance colonoscopy in ulcerative colitis?'
Bernstein, C. N.,Shanahan, F.,Weinstein, W. M. (1994) 'Are we telling patients the truth about surveillance colonoscopy in ulcerative colitis?'. Lancet, 343 (88898889):71-4 [Details]
(1994)'Neurotransmitters and cytokines in CNS pathology'
Mitrovic, B.,Martin, F. C.,Charles, A. C.,Ignarro, L. J.,Anton, P. A.,Shanahan, F.,Merrill, J. E. (1994) 'Neurotransmitters and cytokines in CNS pathology'. Prog Brain Res, 103 :319-30 [Details]
(1994)'Milk tolerance in adults with ulcerative colitis'
Bernstein, C. N.,Ament, M.,Artinian, L.,Ridgeway, J.,Shanahan, F. (1994) 'Milk tolerance in adults with ulcerative colitis'. Am J Gastroenterol, 89 (66):872-7 [Details]
(1993)'Distinct associations of HLA class II genes with inflammatory bowel disease'
Toyoda, H.,Wang, S. J.,Yang, H. Y.,Redford, A.,Magalong, D.,Tyan, D.,McElree, C. K.,Pressman, S. R.,Shanahan, F.,Targan, S. R.,et al., (1993) 'Distinct associations of HLA class II genes with inflammatory bowel disease'. Gastroenterology, 104 (33):741-8 [Details]
(1993)'Familial empirical risks for inflammatory bowel disease: differences between Jews and non-Jews'
Yang, H.,McElree, C.,Roth, M. P.,Shanahan, F.,Targan, S. R.,Rotter, J. I. (1993) 'Familial empirical risks for inflammatory bowel disease: differences between Jews and non-Jews'. Gut, 34 (44):517-24 [Details]
(1993)'VIP modulates intracellular calcium oscillations in human lymphoblasts'
Anton, P. A.,Shanahan, F.,Sun, X. P.,Diehl, D.,Kodner, A.,Mayer, E. A. (1993) 'VIP modulates intracellular calcium oscillations in human lymphoblasts'. Immunopharmacol Immunotoxicol, 15 (44):429-46 [Details]
(1993)'Pneumocystis carinii pneumonia in patients with ulcerative colitis treated with corticosteroids'
Bernstein, C. N.,Kolodny, M.,Block, E.,Shanahan, F. (1993) 'Pneumocystis carinii pneumonia in patients with ulcerative colitis treated with corticosteroids'. Am J Gastroenterol, 88 (44):574-7 [Details]
(1993)'Factor XIII: is it a factor in Crohn's disease?'
Bernstein, C. N.,Shanahan, F. (1993) 'Factor XIII: is it a factor in Crohn's disease?'. Gastroenterology, 105 (22):605-7 [Details]
(1993)'Purine analogues and ulcerative colitis'
Bernstein, C. N.,Shanahan, F. (1993) 'Purine analogues and ulcerative colitis'. Gastroenterology, 104 (11):325-6 [Details]
(1993)'Successful combined liver and small intestine transplantation for short-gut syndrome and liver failure'
Busuttil, R. W.,Farmer, D. G.,Shaked, A.,Rolandelli, R.,Colonna, J. O., 2nd,Jurim, O.,Colquhoun, S. D.,Bernstein, C.,Shanahan, F.,Robert, M.,et al., (1993) 'Successful combined liver and small intestine transplantation for short-gut syndrome and liver failure'. West J Med, 158 (22):184-8 [Details]
(1993)'Production of interleukin-1 by microglia in response to substance P: role for a non-classical NK-1 receptor'
Martin, F. C.,Anton, P. A.,Gornbein, J. A.,Shanahan, F.,Merrill, J. E. (1993) 'Production of interleukin-1 by microglia in response to substance P: role for a non-classical NK-1 receptor'. J Neuroimmunol, 42 (11):53-60 [Details]
(1993)'Pathogenesis of ulcerative colitis'
Shanahan, F. (1993) 'Pathogenesis of ulcerative colitis'. Lancet, 342 (88688868):407-11 [Details]
(1993)'Food allergy: fact, fiction, and fatality'
Shanahan, F. (1993) 'Food allergy: fact, fiction, and fatality'. Gastroenterology, 104 (44):1229-31 [Details]
(1993)'A potential role for the immune system in gastric acid secretion and peptic ulcer disease'
Shanahan, F.,Anton, P. A. (1993) 'A potential role for the immune system in gastric acid secretion and peptic ulcer disease'. Gastroenterology, 104 (66):1874-6 [Details]
(1993)'ANCAs aweigh in colitis'
Shanahan, F.,Bernstein, C. N. (1993) 'ANCAs aweigh in colitis'. Gastroenterology, 105 (33):946-7 [Details]
(1993)'Odd forms of inflammatory bowel disease: what can they tell us?'
Shanahan, F.,Bernstein, C. N. (1993) 'Odd forms of inflammatory bowel disease: what can they tell us?'. Gastroenterology, 104 (11):327-9 [Details]
(1992)'Metronidazole in Crohn's disease: what's the score?'
Bernstein, C. N.,Shanahan, F. (1992) 'Metronidazole in Crohn's disease: what's the score?'. Gastroenterology, 102 (4 Pt 14 Pt 1):1435-6 [Details]
(1992)'Interleukin 8, neutrophils, and acute inflammation'
Shanahan, F.,Bernstein, C. N. (1992) 'Interleukin 8, neutrophils, and acute inflammation'. Gastroenterology, 103 (11):341-3 [Details]
(1992)'Neutrophil autoantibodies in ulcerative colitis: familial aggregation and genetic heterogeneity'
Shanahan, F.,Duerr, R. H.,Rotter, J. I.,Yang, H.,Sutherland, L. R.,McElree, C.,Landers, C. J.,Targan, S. R. (1992) 'Neutrophil autoantibodies in ulcerative colitis: familial aggregation and genetic heterogeneity'. Gastroenterology, 103 (22):456-61 [Details]
(1992)'Braving the elementals in Crohn's disease'
Bernstein, C. N.,Shanahan, F. (1992) 'Braving the elementals in Crohn's disease'. Gastroenterology, 103 (44):1363-4 [Details]
(1992)'Ulcerative colitis-linked antineutrophil cytoplasmic antibody in the cotton-top tamarin model of colitis'
Targan, S. R.,Landers, C. J.,King, N. W.,Podolsky, D. J.,Shanahan, F. (1992) 'Ulcerative colitis-linked antineutrophil cytoplasmic antibody in the cotton-top tamarin model of colitis'. Gastroenterology, 102 (55):1493-8 [Details]
(1992)'Medical treatment of inflammatory bowel disease'
Shanahan, F.,Targan, S. (1992) 'Medical treatment of inflammatory bowel disease'. Annu Rev Med, 43 :125-33 [Details]
(1991)'Development of a biotinylated analog of substance P for use as a receptor probe'
Anton, P. A.,Reeve, J. R., Jr.,Vidrich, A.,Mayer, E.,Shanahan, F. (1991) 'Development of a biotinylated analog of substance P for use as a receptor probe'. Lab Invest, 64 (55):703-8 [Details]
(1991)'Biotinylation of a bombesin/gastrin-releasing peptide analogue for use as a receptor probe'
Anton, P. A.,Reeve, J. R., Jr.,Rivier, J. E.,Vidrich, A.,Schepp, W.,Shanahan, F. (1991) 'Biotinylation of a bombesin/gastrin-releasing peptide analogue for use as a receptor probe'. Peptides, 12 (22):375-81 [Details]
(1991)'Differentiation-associated expression of the Epstein-Barr virus BZLF1 transactivator protein in oral hairy leukoplakia'
Young, L. S.,Lau, R.,Rowe, M.,Niedobitek, G.,Packham, G.,Shanahan, F.,Rowe, D. T.,Greenspan, D.,Greenspan, J. S.,Rickinson, A. B.,et al., (1991) 'Differentiation-associated expression of the Epstein-Barr virus BZLF1 transactivator protein in oral hairy leukoplakia'. J Virol, 65 (66):2868-74 [Details]
(1991)'Role of mucosal T-cell-generated cytokines in epithelial cell injury'
Targan, S. R.,Deem, R. L.,Shanahan, F. (1991) 'Role of mucosal T-cell-generated cytokines in epithelial cell injury'. Immunol Res, 10 (3-43-4):472-8 [Details]
(1991)'Oral mesalamine (Asacol) for mildly to moderately active ulcerative colitis. A multicenter study'
Sninsky, C. A.,Cort, D. H.,Shanahan, F.,Powers, B. J.,Sessions, J. T.,Pruitt, R. E.,Jacobs, W. H.,Lo, S. K.,Targan, S. R.,Cerda, J. J.,et al., (1991) 'Oral mesalamine (Asacol) for mildly to moderately active ulcerative colitis. A multicenter study'. Ann Intern Med, 115 (55):350-5 [Details]
(1991)'Pathways of activation of the Epstein-Barr virus productive cycle'
Sinclair, A. J.,Brimmell, M.,Shanahan, F.,Farrell, P. J. (1991) 'Pathways of activation of the Epstein-Barr virus productive cycle'. J Virol, 65 (55):2237-44 [Details]
(1991)'Colonoscopy during an attack of severe ulcerative colitis'
Shanahan, F.,Targan, S.,Anton, P.,Duerr, R. (1991) 'Colonoscopy during an attack of severe ulcerative colitis'. Am J Gastroenterol, 86 (99) [Details]
(1991)'Neutrophil autoantibodies as disease markers for ulcerative colitis'
Shanahan, F.,Landers, C.,Duerr, R.,Targan, S. R. (1991) 'Neutrophil autoantibodies as disease markers for ulcerative colitis'. Immunol Res, 10 (3-43-4):479-84 [Details]
(1991)'Prevalence and severity of periodontal disease in patients with inflammatory bowel disease'
Flemmig, T. F.,Shanahan, F.,Miyasaki, K. T. (1991) 'Prevalence and severity of periodontal disease in patients with inflammatory bowel disease'. J Clin Periodontol, 18 (99):690-7 [Details]
(1991)'p53 is frequently mutated in Burkitt's lymphoma cell lines'
Farrell, P. J.,Allan, G. J.,Shanahan, F.,Vousden, K. H.,Crook, T. (1991) 'p53 is frequently mutated in Burkitt's lymphoma cell lines'. Embo j, 10 (1010):2879-87 [Details]
(1991)'Anti-neutrophil cytoplasmic antibodies in ulcerative colitis. Comparison with other colitides/diarrheal illnesses'
Duerr, R. H.,Targan, S. R.,Landers, C. J.,Sutherland, L. R.,Shanahan, F. (1991) 'Anti-neutrophil cytoplasmic antibodies in ulcerative colitis. Comparison with other colitides/diarrheal illnesses'. Gastroenterology, 100 (66):1590-6 [Details]
(1991)'Triggered human mucosal T cells release tumour necrosis factor-alpha and interferon-gamma which kill human colonic epithelial cells'
Deem, R. L.,Shanahan, F.,Targan, S. R. (1991) 'Triggered human mucosal T cells release tumour necrosis factor-alpha and interferon-gamma which kill human colonic epithelial cells'. Clin Exp Immunol, 83 (11):79-84 [Details]
(1991)'Isolation and characterization of a cDNA clone corresponding to the mouse t-complex gene Tcp-1x'
Dudley, K.,Shanahan, F.,Burtenshaw, M.,Evans, E. P.,Ruddy, S.,Lyon, M. F. (1991) 'Isolation and characterization of a cDNA clone corresponding to the mouse t-complex gene Tcp-1x'. Genet Res, 57 (22):147-52 [Details]
(1991)'Neutrophil cytoplasmic antibodies: a link between primary sclerosing cholangitis and ulcerative colitis'
Duerr, R. H.,Targan, S. R.,Landers, C. J.,LaRusso, N. F.,Lindsay, K. L.,Wiesner, R. H.,Shanahan, F. (1991) 'Neutrophil cytoplasmic antibodies: a link between primary sclerosing cholangitis and ulcerative colitis'. Gastroenterology, 100 (5 Pt 15 Pt 1):1385-91 [Details]
(1990)'The CD8+ Leu-7+ subset of T cells in Crohn's disease: distinction between cytotoxic and covert suppressor functions'
Deem, R. L.,Targan, S. R.,Niederlehner, A.,Shanahan, F. (1990) 'The CD8+ Leu-7+ subset of T cells in Crohn's disease: distinction between cytotoxic and covert suppressor functions'. Clin Exp Immunol, 80 (33):387-94 [Details]
(1990)'A distinct subset of antineutrophil cytoplasmic antibodies is associated with inflammatory bowel disease'
Saxon, A.,Shanahan, F.,Landers, C.,Ganz, T.,Targan, S. (1990) 'A distinct subset of antineutrophil cytoplasmic antibodies is associated with inflammatory bowel disease'. J Allergy Clin Immunol, 86 (22):202-10 [Details]
(1990)'Sulfasalazine inhibits the binding of TNF alpha to its receptor'
Shanahan, F.,Niederlehner, A.,Carramanzana, N.,Anton, P. (1990) 'Sulfasalazine inhibits the binding of TNF alpha to its receptor'. Immunopharmacology, 20 (33):217-24 [Details]
(1990)'Albinism and Hermansky-Pudlak syndrome in Puerto Rico'
Witkop, C. J.,Nunez Babcock, M.,Rao, G. H.,Gaudier, F.,Summers, C. G.,Shanahan, F.,Harmon, K. R.,Townsend, D.,Sedano, H. O.,King, R. A.,et al., (1990) 'Albinism and Hermansky-Pudlak syndrome in Puerto Rico'. Bol Asoc Med P R, 82 (88):333-9 [Details]
(1989)'Enhanced peripheral blood T-cell cytotoxicity in inflammatory bowel disease'
Shanahan, F.,Leman, B.,Deem, R.,Niederlehner, A.,Brogan, M.,Targan, S. (1989) 'Enhanced peripheral blood T-cell cytotoxicity in inflammatory bowel disease'. J Clin Immunol, 9 (11):55-64 [Details]
(1989)'Temporal expression and location of colony-stimulating factor 1 (CSF-1) and its receptor in the female reproductive tract are consistent with CSF-1-regulated placental development'
Arceci, R. J.,Shanahan, F.,Stanley, E. R.,Pollard, J. W. (1989) 'Temporal expression and location of colony-stimulating factor 1 (CSF-1) and its receptor in the female reproductive tract are consistent with CSF-1-regulated placental development'. Proc Natl Acad Sci U S A, 86 (2222):8818-22 [Details]
(1989)'Increased neutrophil receptors for and response to the proinflammatory bacterial peptide formyl-methionyl-leucyl-phenylalanine in Crohn's disease'
Anton, P. A.,Targan, S. R.,Shanahan, F. (1989) 'Increased neutrophil receptors for and response to the proinflammatory bacterial peptide formyl-methionyl-leucyl-phenylalanine in Crohn's disease'. Gastroenterology, 97 (11):20-8 [Details]
(1989)'Lack of an association between polymorphisms of the T-cell receptor alpha-chain and ulcerative colitis'
Randolph, L. M.,Toyoda, H.,McElree, C. K.,Shanahan, F.,Targan, S. R.,Rotter, J. I. (1989) 'Lack of an association between polymorphisms of the T-cell receptor alpha-chain and ulcerative colitis'. Gastroenterology, 97 (55):1115-20 [Details]
(1988)'Human mucosal T-cell cytotoxicity'
Shanahan, F.,Deem, R.,Nayersina, R.,Leman, B.,Targan, S. (1988) 'Human mucosal T-cell cytotoxicity'. Gastroenterology, 94 (44):960-7 [Details]
(1988)'Extending the scope in celiac disease'
Shanahan, F.,Weinstein, W. M. (1988) 'Extending the scope in celiac disease'. N Engl J Med, 319 (1212):782-3 [Details]
(1988)'Neuroendocrine modulation of the immune system. Possible implications for inflammatory bowel disease'
Shanahan, F.,Anton, P. (1988) 'Neuroendocrine modulation of the immune system. Possible implications for inflammatory bowel disease'. Dig Dis Sci, 33 (3 Suppl3 Suppl) [Details]
(1988)'Hidradenitis suppurativa. Glucose tolerance, clinical, microbiologic, and immunologic features and HLA frequencies in 27 patients'
O'Loughlin, S.,Woods, R.,Kirke, P. N.,Shanahan, F.,Byrne, A.,Drury, M. I. (1988) 'Hidradenitis suppurativa. Glucose tolerance, clinical, microbiologic, and immunologic features and HLA frequencies in 27 patients'. Arch Dermatol, 124 (77):1043-6 [Details]
(1988)'Role of the CD45 (T-200) molecule in anti-CD3-triggered T cell-mediated cytotoxicity'
Deem, R. L.,Shanahan, F.,Niederlehner, A.,Targan, S. R. (1988) 'Role of the CD45 (T-200) molecule in anti-CD3-triggered T cell-mediated cytotoxicity'. Cell Immunol, 117 (11):99-110 [Details]
(1988)'Enhanced neutrophil chemiluminescence in familial Mediterranean fever'
Anton, P. A.,Targan, S. R.,Vigna, S. R.,Durham, M.,Schwabe, A. D.,Shanahan, F. (1988) 'Enhanced neutrophil chemiluminescence in familial Mediterranean fever'. J Clin Immunol, 8 (22):148-56 [Details]
(1988)'Modulation of histamine release from canine fundic mucosal mast cells'
Soll, A. H.,Toomey, M.,Culp, D.,Shanahan, F.,Beaven, M. A. (1988) 'Modulation of histamine release from canine fundic mucosal mast cells'. Am J Physiol, 254 (1 Pt 11 Pt 1) [Details]
(1988)'Hermansky-Pudlak syndrome: an immunologic assessment of 15 cases'
Shanahan, F.,Randolph, L.,King, R.,Oseas, R.,Brogan, M.,Witkop, C.,Rotter, J.,Targan, S. (1988) 'Hermansky-Pudlak syndrome: an immunologic assessment of 15 cases'. Am J Med, 85 (66):823-8 [Details]
(1987)'Cytotoxic lymphocytes in human intestinal mucosa'
Shanahan, F.,Brogan, M.,Nayersina, R.,Targan, S. (1987) 'Cytotoxic lymphocytes in human intestinal mucosa'. Adv Exp Med Biol, 216a :457-63 [Details]
(1987)'Defective memory B cell formation in patients with inflammatory bowel disease following tetanus toxoid booster immunization'
Brogan, M. D.,Shanahan, F.,Oliver, M.,Stevens, R. H.,Targan, S. R. (1987) 'Defective memory B cell formation in patients with inflammatory bowel disease following tetanus toxoid booster immunization'. J Clin Lab Immunol, 24 (22):69-74 [Details]
(1987)'Human mucosal cytotoxic effector cells'
Shanahan, F.,Brogan, M.,Targan, S. (1987) 'Human mucosal cytotoxic effector cells'. Gastroenterology, 92 (66):1951-7 [Details]
(1987)'Modulation of ongoing human immunoglobulin synthesis by natural killer cells'
Kimata, H.,Shanahan, F.,Brogan, M.,Targan, S.,Saxon, A. (1987) 'Modulation of ongoing human immunoglobulin synthesis by natural killer cells'. Cell Immunol, 107 (11):74-88 [Details]
(1987)'Immunologic mechanisms in intestinal diseases'
Targan, S. R.,Kagnoff, M. F.,Brogan, M. D.,Shanahan, F. (1987) 'Immunologic mechanisms in intestinal diseases'. Ann Intern Med, 106 (66):853-70 [Details]
(1987)'Sulfasalazine and salicylate-induced exacerbation of ulcerative colitis'
Shanahan, F.,Targan, S. (1987) 'Sulfasalazine and salicylate-induced exacerbation of ulcerative colitis'. N Engl J Med, 317 (77) [Details]
(1987)'Human lung mast cells: distribution and abundance of histochemically distinct subpopulations'
Shanahan, F.,MacNiven, I.,Dyck, N.,Denburg, J. A.,Bienenstock, J.,Befus, A. D. (1987) 'Human lung mast cells: distribution and abundance of histochemically distinct subpopulations'. Int Arch Allergy Appl Immunol, 83 (33):329-31 [Details]
(1986)'Mast cell heterogeneity: effect of anti-allergic compounds on neuropeptide-induced histamine release'
Shanahan, F.,Lee, T. D.,Bienenstock, J.,Befus, A. D. (1986) 'Mast cell heterogeneity: effect of anti-allergic compounds on neuropeptide-induced histamine release'. Int Arch Allergy Appl Immunol, 80 (44):424-6 [Details]
(1986)'Inhibition of cytotoxicity by sulfasalazine. II. Sulfasalazine and sulfapyridine inhibit different stages of the NK and NKCF lytic processes'
Shanahan, F.,Niederlehner, A.,MacDermott, R. P.,Stenson, W. F.,Kane, M. G.,Targan, S. (1986) 'Inhibition of cytotoxicity by sulfasalazine. II. Sulfasalazine and sulfapyridine inhibit different stages of the NK and NKCF lytic processes'. Immunopharmacology, 11 (22):111-8 [Details]
(1986)'Functional characterization of mast cells generated in vitro from the mesenteric lymph node of rats infected with Nippostrongylus brasiliensis'
Shanahan, F.,Lee, T. D.,Denburg, J. A.,Bienenstock, J.,Befus, A. D. (1986) 'Functional characterization of mast cells generated in vitro from the mesenteric lymph node of rats infected with Nippostrongylus brasiliensis'. Immunology, 57 (33):455-9 [Details]
(1986)'K562 killing by K, IL 2-responsive NK, and T cells involves different effector cell post-binding trigger mechanisms'
Shanahan, F.,Brogan, M. D.,Newman, W.,Targan, S. R. (1986) 'K562 killing by K, IL 2-responsive NK, and T cells involves different effector cell post-binding trigger mechanisms'. J Immunol, 137 (22):723-6 [Details]
(1985)'Mast cell heterogeneity: effects of neuroenteric peptides on histamine release'
Shanahan, F.,Denburg, J. A.,Fox, J.,Bienenstock, J.,Befus, D. (1985) 'Mast cell heterogeneity: effects of neuroenteric peptides on histamine release'. J Immunol, 135 (22):1331-7 [Details]
(1985)'The pancreas, primary biliary cirrhosis and the dry gland syndrome'
Shanahan, F.,Stack, J.,Maguire, S.,Crowe, J. (1985) 'The pancreas, primary biliary cirrhosis and the dry gland syndrome'. Ir J Med Sci, 154 (1010):387-9 [Details]
(1985)'Intestinal mucosal mast cells: isolation from rat lamina propria and purification using unit gravity velocity sedimentation'
Lee, T. D.,Shanahan, F.,Miller, H. R.,Bienenstock, J.,Befus, A. D. (1985) 'Intestinal mucosal mast cells: isolation from rat lamina propria and purification using unit gravity velocity sedimentation'. Immunology, 55 (44):721-8 [Details]
(1985)'Comparative aspects of mast cell heterogeneity in different species and sites'
Bienenstock, J.,Befus, D.,Denburg, J.,Goto, T.,Lee, T.,Otsuka, H.,Shanahan, F. (1985) 'Comparative aspects of mast cell heterogeneity in different species and sites'. Int Arch Allergy Appl Immunol, 77 (1-21-2):126-9 [Details]
(1985)'Indium-111 leukocyte imaging in colitis induced by Clostridium difficile'
Asbill, M. C.,Shanahan, F.,Van Deventer, G. M. (1985) 'Indium-111 leukocyte imaging in colitis induced by Clostridium difficile'. J Nucl Med, 26 (33):315-6 [Details]
(1984)'The influence of endorphins on peritoneal and mucosal mast cell secretion'
Shanahan, F.,Lee, T. D.,Bienenstock, J.,Befus, A. D. (1984) 'The influence of endorphins on peritoneal and mucosal mast cell secretion'. J Allergy Clin Immunol, 74 (4 Pt 14 Pt 1):499-504 [Details]
(1984)'Mast cell heterogeneity'
Shanahan, F.,Denburg, J. A.,Bienenstock, J.,Befus, A. D. (1984) 'Mast cell heterogeneity'. Can J Physiol Pharmacol, 62 (66):734-7 [Details]
(1983)'Factor V deficiency and its reversal with gluten restriction. In a patient with celiac disease'
Shanahan, F.,Aburajab, A.,Goodacre, R.,Blajchman, M. A. (1983) 'Factor V deficiency and its reversal with gluten restriction. In a patient with celiac disease'. Arch Intern Med, 143 (1010):2009-10 [Details]
(1983)'Primary Biliary Cirrhosis associated with Coeliac Disease'
Shanahan, F.,O'Regan, P. F.,Crowe, J. P. (1983) 'Primary Biliary Cirrhosis associated with Coeliac Disease'. Ir Med J, 76 (66) [Details]
(1983)'Endoscopic sphincterotomy'
O'Regan, P. F.,Shanahan, F.,Gallagher, C.,Crowe, J. P.,Lennon, J. R. (1983) 'Endoscopic sphincterotomy'. Ir J Med Sci, 152 (1010):373-6 [Details]
(1983)'Mast cell heterogeneity'
Bienenstock, J.,Befus, A. D.,Denburg, J.,Goodacre, R.,Pearce, F.,Shanahan, F. (1983) 'Mast cell heterogeneity'. Monogr Allergy, 18 :124-8 [Details]
(1982)'Successful endoscopic removal of a common bile duct foreign body'
O'Regan, P. F.,Shanahan, F.,Lennon, J. R.,Crowe, J. (1982) 'Successful endoscopic removal of a common bile duct foreign body'. Endoscopy, 14 (11):26-7 [Details]
(1982)'Coeliac disease and diabetes mellitus: a study of 24 patients with HLA typing'
Shanahan, F.,McKenna, R.,McCarthy, C. F.,Drury, M. I. (1982) 'Coeliac disease and diabetes mellitus: a study of 24 patients with HLA typing'. Q J Med, 51 (203203):329-35 [Details]
(1981)'Cerebral intravascular coagulation complicating diabetic ketoacidosis'
Shanahan, F.,Mortimer, G.,Drury, M. I. (1981) 'Cerebral intravascular coagulation complicating diabetic ketoacidosis'. Ir J Med Sci, 150 (55):156-7 [Details]
(1981)'Hereditary angioedema--a cause of abdominal pain, often missed?'
O'Regan, P. F.,Shanahan, F.,Barnes, L.,Lennon, J. R. (1981) 'Hereditary angioedema--a cause of abdominal pain, often missed?'. Ir J Med Sci, 150 (1111):335-7 [Details]
(1981)'Cimetidine and the control of pain in chronic relapsing pancreatitis'
Shanahan, F.,Crowe, J. (1981) 'Cimetidine and the control of pain in chronic relapsing pancreatitis'. N Engl J Med, 305 (1111) [Details]
(1981)'Sonolucent biliary cast preventing endoscopic sphincterotomy'
Shanahan, F.,Lennon, J.,Corrigan, T. (1981) 'Sonolucent biliary cast preventing endoscopic sphincterotomy'. Endoscopy, 13 (55) [Details]
(1978)'Atenolol self-poisoning'
Shanahan, F. L.,Counihan, T. B. (1978) 'Atenolol self-poisoning'. Br Med J, 2 (61396139) [Details]
(1977)'Mechanisms in autoimmune diseases'
Shanahan, F.,McLaughlin, H. (1977) 'Mechanisms in autoimmune diseases'. Ir Med J, 70 (1616):472-9 [Details]

Books

YearPublication
(2011)Clinical Dilemmas in Inflammatory Bowel Disease: New Challenges, 2nd Edition.
Irving P, Siegel C, Rampton D, Shanahan F. (2011) Clinical Dilemmas in Inflammatory Bowel Disease: New Challenges, 2nd Edition. London: Blackwell Publishing Ltd. [Details]
(2010)Inflammatory Bowel Disease. Translating basic science into clinical practice.
Targan S, Shanahan F, Karp LC. (2010) Inflammatory Bowel Disease. Translating basic science into clinical practice. London: Wiley-Blackwell. [Details]
(2008)Mycobacterium avium subspecies paratuberculosis and Crohn’s disease.
Shanahan F (2008) Mycobacterium avium subspecies paratuberculosis and Crohn’s disease. London: Remedica. [Details]
(2008)3rd edition Inflammatory bowel disease: Fast Facts.
Rampton D, Shanahan F. (2008) 3rd edition Inflammatory bowel disease: Fast Facts. London: Healthcare Press. [Details]
(2007)Pregnancy-related gastrointestinal & hepatological diseases and complications - Preface.
Shanahan, Fergus (2007) Pregnancy-related gastrointestinal & hepatological diseases and complications - Preface. [Details]
(2006)Clinical dilemmas in IBD.
Irving P, Rampton D, Shanahan F. (2006) Clinical dilemmas in IBD. London: Blackwell Scientific. [Details]
(2006)2nd Inflammatory bowel disease: Fast Facts.
Rampton D, Shanahan F. (2006) 2nd Inflammatory bowel disease: Fast Facts. London: Healthcare Press. [Details]
(2003)Inflammatory Bowel Disease: From Bench to Bedside (2nd edition).
Targan S, Shanahan F, Karp L. (2003) Inflammatory Bowel Disease: From Bench to Bedside (2nd edition). Dordrecht: Kluwer Academic. [Details]
(2001)Inflammatory bowel disease: Fast Facts.
Rampton D, Shanahan F. (2001) Inflammatory bowel disease: Fast Facts. London: Healthcare Press. [Details]
(1994)Inflammatory Bowel Disease: From Bench to Bedside.
Targan S and Shanahan F. (editors) (1994) Inflammatory Bowel Disease: From Bench to Bedside. Baltimore: Williams & Wilkins. [Details]
(1990)Immunology and Immunopathology of the Liver and Gastrointestinal Tract.
Targan S and Shanahan F. (editors) (1990) Immunology and Immunopathology of the Liver and Gastrointestinal Tract. New York and Tokyo: Igaku-Shoin. [Details]

Book Chapters

YearPublication
(2014)'What is the role of probiotics in my patients with inflammatory bowel disease?'
Shanahan F (2014) 'What is the role of probiotics in my patients with inflammatory bowel disease?' In: Curbside Consultation in IBD: 49 Clinical Questions. USA: SLACK Inc. [Details]
(2011)'How do we minimise radiation exposure in IBD?'
O’Connor OJ, Desmond A, Shanahan F, Maher MM. (2011) 'How do we minimise radiation exposure in IBD?' In: Clinical Dilemmas in Inflammatory Bowel Disease: New Challenges, Editors: Irving D, Shanahan F, Siegel C. USA: Blackwell Publishing. [Details]
(2011)'The luminal contents in IBD: what clinicians should know about the microbiota and its manipulation'
Shanahan F (2011) 'The luminal contents in IBD: what clinicians should know about the microbiota and its manipulation' In: Advanced Therapy of inflammatory bowel disease. USA: People’s medical Publishing house. [Details]
(2011)'The intestinal microbiota in health and disease'
Shanahan F (2011) 'The intestinal microbiota in health and disease' In: Integrative Gastroenterology. UK: Oxford University Press. [Details]
(2010)'Probiotics in Irritable Bowel Syndrome'
Quigley EMM, Shanahan F; (2010) 'Probiotics in Irritable Bowel Syndrome' In: Nutritional Management of Digestive Disorders. Philadelphia: Taylor and Francis Group. [Details]
(2010)'50 Clinical Dilemmas in IBD'
Quigley, EMM; Rampton, D; Irving, P; Shanahan, F; (2010) '50 Clinical Dilemmas in IBD' In: 50 Clinical Dilemmas in IBD. Blackwell Publishing: Blackwell Publishing. [Details]
(2010)'Thereapeutic manipulation of the microbiota in inflammatory bowel disease: antibiotics and probiotics'
Keohane J, Shanahan F (2010) 'Thereapeutic manipulation of the microbiota in inflammatory bowel disease: antibiotics and probiotics' In: Inflammatory Bowel Disease. Translating basic science into clinical practice. UK: Wiley-Blackwell. [Details]
(2010)'The present and future of research and treatment in inflammatory bowel disease'
Targan SR, Karp LC, Shanahan F (2010) 'The present and future of research and treatment in inflammatory bowel disease' In: Inflammatory Bowel Disease. Translating basic science into clinical practice. UK: Wiley-Blackwell. [Details]
(2009)'Gut microbiota and abnormal mucosal neuroendocrine immune activation'
Spiller R, Shanahan F (2009) 'Gut microbiota and abnormal mucosal neuroendocrine immune activation' In: Functional Pain Syndromes: Presentation and Pathophysiology. Seattle: IASP Press. [Details]
(2009)'Lactobacillus in the gastrointestinal tract'
Keohane J, Ryan K, Shanahan F (2009) 'Lactobacillus in the gastrointestinal tract' In: Lactobacillus molecular biology. From genomics to probiotics. UK: Caister Academic Press. [Details]
(2009)'Linking lifestyle with microbiota and risk of chronic inflammatory disorders'
Shanahan F (2009) 'Linking lifestyle with microbiota and risk of chronic inflammatory disorders' In: The Hygiene Hypothesis and Darwinian Medicine. Basel/Switzerland: Birkhauser Verlag. [Details]
(2006)'The enteric bacterial flora and small bowel overgrowth'
O'Mahony S, Shanahan F.; (2006) 'The enteric bacterial flora and small bowel overgrowth' In: Scleisenger & Fordtran. Textbook of Gastroenterology. [Details]
(2004)'Synbiotics in colon cancer'
Bennett MF, Clune YE, Shanahan F, O'Sullivan G, Collins JK.; (2004) 'Synbiotics in colon cancer' In: Functional Foods: ageing and degenerative disease. [Details]
(2004)'Probiotics in inflammatory bowel disease'
McCarthy J, Sheil B, O’Mahony L, Anwar MM, Shanahan F.; (2004) 'Probiotics in inflammatory bowel disease' In: Functional foods: ageing and degenerative disease. [Details]
(2002)'Mycobacterium paratuberculosis detected by nested PCR in intestinal granulomas isolated by LCM in cases of Crohn's disease'
Ryan, Paul and Aarons, Simon and Bennett, Michael W. and Lee, Gary and O'Sullivan, Gerald C. and O'Connell, Joe and Shanahan, Fergus (2002) 'Mycobacterium paratuberculosis detected by nested PCR in intestinal granulomas isolated by LCM in cases of Crohn's disease' In: Methods in molecular biology (Clifton, N.J.). [Details]
(2002)'RT-PCR for the assessment of genetically heterogenous populations of the hepatitis C virus'
Mullan, Brian and Fanning, Liam J. and Shanahan, Fergus and Sullivan, Daniel G. (2002) 'RT-PCR for the assessment of genetically heterogenous populations of the hepatitis C virus' In: Methods In Molecular Biology. London: Humana Press. [DOI] [Details]
(2000)'Probiotic bacteria and the human immune system'
O'Mahony L, Feeny M, Dunne C, O'Halloran S, Murphy L, Kiely B, O'Sullivan GC, Shanahan F and Collins JK. ; (2000) 'Probiotic bacteria and the human immune system' In: Functional foods claims and evidence. London: British Nutrition Foundation / J. Royal Society of Chemistry. [Details]
(1998)'Adenocarcinoma of the oesophago gastric function. What is the role of suppression of T-lymphocyte function?'
O'Sullivan GC, O'Brien MG, O'Connell J, Collins JK, and Shanahan F. ; (1998) 'Adenocarcinoma of the oesophago gastric function. What is the role of suppression of T-lymphocyte function?' In: The Esophagogastric Junction. Paris: John Libbey Eurotext. [Details]
(1994)'Immunosuppressive agents in inflammatory bowel disease'
Shanahan F, O'Sullivan GC and Collins JK. ; (1994) 'Immunosuppressive agents in inflammatory bowel disease' In: Inflammatory bowel disease: basic research clinical implications. Dordrecht, Netherlands: Kluwer academic publishers. [Details]
(1992)'Inflammatory Bowel Disease'
Shanahan F, Targan S. (1992) 'Inflammatory Bowel Disease' In: Textbook of Internal Medicine. Philadelphia: J.B. Lippincott Co. [Details]
(1991)'Steroids and Inflammatory Bowel Disease'
Kuritzkes R, Shanahan F. (1991) 'Steroids and Inflammatory Bowel Disease' In: Inflammatory Bowel Disease: Diagnosis and Treatment. New York &Tokyo: Igaku-Shoin. [Details]
(1991)'Immunology of Inflammatory Bowel Disease'
Targan S, Karp L, Shanahan F. (1991) 'Immunology of Inflammatory Bowel Disease' In: Inflammatory Bowel Disease: Diagnosis and Treatment. New York & Tokyo: Igaku-Shoin. [Details]
(1991)'Immunologic Diseases: Gastrointestinal manifestations of immunodeficiency, hypersensitivity, and graft versus host disease'
Shanahan F, Targan S. (1991) 'Immunologic Diseases: Gastrointestinal manifestations of immunodeficiency, hypersensitivity, and graft versus host disease' In: Textbook of Gastroenterology. Philadelphia: JB Lippincott Company. [Details]
(1990)'Food Allergy'
Duerr R, Shanahan F. (1990) 'Food Allergy' In: Immunology and Immunopathology of the Liver and Gastrointestinal Tract. New York & Tokyo: Igaku-Shoin. [Details]
(1990)'Immunology of the liver and gastrointestinal tract: a perspective'
Shanahan F., Targan S. (1990) 'Immunology of the liver and gastrointestinal tract: a perspective' In: Immunology and Immunopathology of the Liver and Gastrointestinal Tract. New York & Tokyo: Igaku-Shoin. [Details]
(1990)'Food allergy, eosinophilic gastroenteritis and systemic mastocytosis'
Shanahan F. (1990) 'Food allergy, eosinophilic gastroenteritis and systemic mastocytosis' In: Current Therapy in Gastroenterology and Liver Disease. Hamilton, Ontario: B.C. Decker Inc. [Details]
(1989)'Role of natural effector cells in human gastrointestinal disease'
Shanahan F, Targan S. (1989) 'Role of natural effector cells in human gastrointestinal disease' In: Functions of the Natural Immune System. New York: Plenum Publishing Corporation. [Details]
(1989)'Inflammatory Bowel Disease'
Shanahan F, Targan S. (1989) 'Inflammatory Bowel Disease' In: Textbook of Internal Medicine. Philadelphia: J.B. Lippincott Co. [Details]
(1989)'The immunology of inflammatory bowel disease'
Shanahan F, Targan S. (1989) 'The immunology of inflammatory bowel disease' In: Modern Concepts in Gastroenterology Volume 2. New York: Plenum Publishing Corporation. [Details]
(1988)'Ulcerative colitis and Crohn's Disease edited by'
Shanahan F, Targan S. (1988) 'Ulcerative colitis and Crohn's Disease edited by' In: Current Therapy in Allergy, Immunology, and Rheumatology. Hamilton, Ontario: B.C. Decker Inc. [Details]
(1988)'Immunological mechanisms of liver injury'
Shanahan F, Targan SR. (1988) 'Immunological mechanisms of liver injury' In: Principles and Practice of Gastroenterology and Hepatology. New York: Elsevier Science Publishing Co., Inc. [Details]
(1986)'Food allergy and adverse reactions: current status'
Shanahan F, Targan SR. (1986) 'Food allergy and adverse reactions: current status' In: Modern Concepts in Gastroenterology. Volume 1. New York: Plenum Publishing Corporation. [Details]

Conference Publications

YearPublication
(2014)DDW, Chicago 2014
O’Mahony C, Clarke SF, Hurley G, O'Sullivan O, Gavin A, Quinlan A, Houston A, Mahmoud A, Bennett MW, Cotter PD, Shanahan F and Melgar S. (2014) High fat feeding alters gut microbiota and protects mice from colitis and colitis-associated colorectal cancer DDW, Chicago 2014 [Details]
(2013)British and Irish Gastroenterology (BIG) Spring Meeting, Belfast, April 2013
Kennedy PJ, Clarke G, Allen AP, Ann O’Neill A, Groeger JA, Quigley EM, Shanahan F , Cryan JF, Dinan TG. (2013) A Prospective Study of Cognitive Performance in Irritable Bowel Syndrome: Visuospatial Memory Deficits as a Stable Feature British and Irish Gastroenterology (BIG) Spring Meeting, Belfast, April 2013 [Details]
(2013)Royal Academy of Medicine in Ireland, Section of Biomedical Sciences, University College Cork, June 20th
Ogbonnaya S., Clarke G., Shanahan F., Cryan J. F., O’Leary, O.F. (2013) Establishment of the gut microbiome during early-life influences the survival of newly-born cells in the adult hippocampus Royal Academy of Medicine in Ireland, Section of Biomedical Sciences, University College Cork, June 20th [Details]
(2013)Digestive Disease Week, Florida, USA, May 2013
Kennedy PJ, Clarke G, Allen AP, Ann O’Neill A, Groeger JA, Quigley EM, Shanahan F , Cryan JF, Dinan TG (2013) A Prospective Assessment of Cognitive Performance in Irritable Bowel Syndrome Reveals Persistent Visuospatial Memory Deficits Digestive Disease Week, Florida, USA, May 2013 [Details]
(2013)International Behavioural Neuroscience Society Annual Meeting, Dublin, 25th -30th June 2013
Ogbonnaya S., Clarke G., Shanahan, F., Dinan T.G., Cryan, J. F., O’Leary, O.F. (2013) The microbiome-gut-brain axis regulates the survival of newly-born cells in the adult hippocampus International Behavioural Neuroscience Society Annual Meeting, Dublin, 25th -30th June 2013 [Details]
(2012)DDW 2012; Gastroenterology
Hall, L. J.,Murphy, C.,Quinlan, A.,Hurley, G.,Shanahan, F.,Nally, K.,Melgar, S. (2012) NK Cells Protect Mice During Acute Experimental Colitis by Regulating Neutrophil Function via NKG2A-dependent Mechanisms DDW 2012; Gastroenterology Globe icon [Details]
(2012)Digestive Disease Week
Ambrose M, Moloney G, Heuston S, Rahman A, Davies JM, Murphy C, Hurley G, Quinlan A, Karras J, Hessel EM, Prinjha R, Lee K, Hyland NP, Shanahan F, Hammarstrom M-L, Melgar S, Nally K (2012) MiR-375 is a Key Regulator of Intestinal Homeostasis in Response to Inflammatory Stress Digestive Disease Week Globe icon [Details]
(2012)Neurogastroenterology and Motility, Bologna, Italy, September 2012
Kennedy PJ, Clarke G, O’Neill A, Groeger JA, Quigley EM, Shanahan F , Cryan JF, Dinan TG (2012) An evaluation of neuropsychological performance in Irritable Bowel Syndrome (IBS): Relationship between altered visuo-spatial memory function, salivary cortisol levels and tryptophan metabolism along the kynurenine pathway Neurogastroenterology and Motility, Bologna, Italy, September 2012 [Details]
(2012)DDW 2012; Gastroenterology
Moloney, G.,Fanning, A.,Mac Sharry, J.,Hall, L. J.,Shanahan, F.,Quigley, E. M.,Melgar, S.,Nally, K. (2012) Altered Expression and Activation of the CXCR3/CXCL10 Chemokine System in Irritable Bowel Syndrome (IBS) Mucosal Biopsy Tissue DDW 2012; Gastroenterology Globe icon [Details]
(2012)DDW 2012; Gastroenterology
Fanning, A.,Moloney, G.,MacSharry, J.,Ambrose, M.,Quigley, E. M.,Shanahan, F.,Melgar, S.,Nally, K. (2012) Elevated Expression of the Cytosolic DNA Sensors AIM2 and ZBP1/DAI in Active Ulcerative Colitis but Not Crohn's Disease Colonic Tissue DDW 2012; Gastroenterology Globe icon [Details]
(2012)DDW 2012; Gastroenterology
Fanning, A.,Moloney, G.,MacSharry, J.,Ambrose, M.,Prinjha, R.,Lee, K.,Quigley, E. M.,Shanahan, F.,Melgar, S.,Nally, K. (2012) Differential Expression of Epigenetic Modifier Genes in Inflammatory Bowel Disease Colonic Tissue-PRDM1 and PRDM8 are up-Regulated in Active Ulcerative Colitis DDW 2012; Gastroenterology Globe icon [Details]
(2012)Neurogastroenterology and Motility, Bologna, Italy, September 2012
Clarke G, Grenham S, Scully P, Fitzgerald P, Shanahan F, Dinan TG, Cryan JF (2012) The Microbiome-Gut-Brain Axis as a Regulator of Serotonergic Neurotransmission and Behaviour Neurogastroenterology and Motility, Bologna, Italy, September 2012 [Details]
(2012)DDW 2012; Gastroenterology
Darby, T.,Clarke, D.,Nally, K.,Shanahan, F.,Melgar, S. (2012) Deficiency in ATG16L1 Increases the Ability of the Adherent-Invasive Escherichia coli (HM605) to Replicate in and Reduce Barrier Integrity of Intestinal Epithelial Cells DDW 2012; Gastroenterology Globe icon [Details]
(2012)National Conference 2012
Kennedy, B.,Kennedy, M. P.,Plant, B. J.,Henry, M. T.,O'Driscoll, M.,Maher, M.,Nally, K.,Shanahan, F.,Curran, D. R.,O'Connor, T. M. (2012) Bone Marrow and Peripheral Blood Derived CD14(+) Cells as Agents of Tissue Remodelling in Idiopathic Pulmonary Fibrosis National Conference 2012 Globe icon [Details]
(2012)Digestive Disease Week (San Diego, USA, May 2012)
Kennedy PJ, Clarke G, O’Neill A, Groeger JA, Quigley EM, Shanahan F , Cryan JF, Dinan TG (2012) An assessment of cognitive function in irritable bowel syndrome (IBS): Are deficits in episodic memory stress-related and mediated by tryptophan metabolism along the kynurenine pathway? Digestive Disease Week (San Diego, USA, May 2012) [Details]
(2012)Digestive Disease Week (San Diego, USA, May 2012)
Clarke G, Grenham S, Scully P, Fitzgerald P, Shanahan F, Dinan TG, Cryan JF (2012) Regulation of Serotonergic Neurotransmission and Behaviour by the Brain-Gut-Microbiome Axis Digestive Disease Week (San Diego, USA, May 2012) [Details]
(2012)DDW 2012; Gastroenterology
Ambrose, M.,Moloney, G.,Heuston, S.,Rahman, A.,Davies, J. M.,Murphy, C.,Hurley, G.,Quinlan, A.,Karras, J.,Hessel, E. M.,Prinjha, R.,Lee, K.,Hyland, N. P.,Shanahan, F.,Hammarstrom, M. L.,Melgar, S.,Nally, K. (2012) MiR-375 is a Key Regulator of Intestinal Homeostasis in Response to Inflammatory Stress DDW 2012; Gastroenterology Globe icon [Details]
(2011)DDW 2011; Gastroenterology
Lapthorne, S.,MacSharry, J.,Scully, P.,Nally, K.,Shanahan, F. (2011) The Discriminatory Intelligence of M Cells - Beyond a Simple Translocation Portal DDW 2011; Gastroenterology Globe icon [Details]
(2011)DDW 2011; Gastroenterology
Ambrose, M.,O'Keeffe, A.,Fanning, A.,Murphy, C.,Hurley, G.,Quinlan, A.,Mac Sharry, J.,Hammarstrom, M. L.,Hessel, E. M.,Lee, K.,Shanahan, F.,Melgar, S.,Nally, K. (2011) MiR-146a Negatively Regulates IL-17A Inflammatory Response and is Elevated in Intestinal Epithelial Cells From Inflammatory Bowel Disease (IBD) Patients DDW 2011; Gastroenterology Globe icon [Details]
(2011)DDW 2011; Gastroenterology
Woznicki, J.,Shanahan, F.,Melgar, S.,Nally, K. (2011) IFN-gamma and TNF-alpha Synergise to Induce Expression of the Novel PRO-Apoptotic Gene BCL-G and Apoptosis in Intestinal Epithelial Cells and BCL-G Expression is Reduced in Inflammatory Bowel Disease (IBD) and Colon Cancer DDW 2011; Gastroenterology Globe icon [Details]
(2011)DDW 2011; Gastroenterology
Moloney, G.,Fanning, A.,O'Malley, D.,Scanlan, N.,Cryan, J. F.,Dinan, T. G.,Shanahan, F.,Quigley, E. M.,Melgar, S.,Nally, K. (2011) Stimulation of T-Cells in Irritable Bowel Syndrome (IBS) Mucosal Biopsy Tissue Releases Cytokines Which Selectively Activate Submucosal Neurons DDW 2011; Gastroenterology Globe icon [Details]
(2011)DDW 2011; Gastroenterology
Murphy, C.,Hall, L. J.,Hurley, G.,Quinlan, A.,Shanahan, F.,Nally, K.,Melgar, S. (2011) The Immunomodulatory Drug FTY720 Prevents Clearance of Citrobacter rodentium Infection in Mice DDW 2011; Gastroenterology Globe icon [Details]
(2010)Psychoneuroimmunology Research Society (Trinity College, Dublin, June 2010)
Scully P, Clarke G, Grenham S, Fitzgerald P, O’Mahony CM, ,McKernan DP,Tramullas M,Shanahan F, Dinan TG, & Cryan JF (2010) Gender-Dependent Influence of the Gut Microbiome on the Hippocampal 5-HT System Psychoneuroimmunology Research Society (Trinity College, Dublin, June 2010) [Details]
(2010)Health and Medicine Research Day (Brookfield, Cork, June 2010)
9. Scully P, Clarke G, Grenham S, Fitzgerald P, O’Mahony CM, ,McKernan DP,Tramullas M,Shanahan F, Dinan TG, & Cryan JF (2010) Gender-Dependent Influence of the Gut Microbiome on the Hippocampal 5-HT System Health and Medicine Research Day (Brookfield, Cork, June 2010) [Details]
(2010)Microbes and Health Sackler Colloquium
Claesson, MJ; Cusack, S; O'Sullivan, O; Greene-Diniz, R; de Weerd, H; Flannery, E; Marchesi, JR; Falush, D; Dinan, T; Fitzgerald, G; Stanton, C; van Sinderen, D; O'Connor, M; Harnedy, N; O'Connor, K; Henry, C; O'Mahony, D; Fitzgerald, AP; Shanahan, F; Twomey, C;Hill, C; Ross, RP; O'Toole, PW; (2010) Composition, variability, and temporal stability of the intestinal microbiota of the elderly Microbes and Health Sackler Colloquium [DOI] [Details]
(2010)European Congress of Radiology
McSweeney SM, O’Connor OJ, O’Regan K, Desmond A, Shanahan F, Quigley E, Maher MM. (2010) The use of diagnostic imaging in irritable bowel syndrome patients European Congress of Radiology [Details]
(2010)Society for Neuroscience (San Diego, USA, November 2010)
Tramullas M, Clarke G, Shanahan F, Dinan TG, Cryan JF (2010) The gut microbiome alters toll-like receptor and cytokine expression levels in the spinal cord: Role of gender Society for Neuroscience (San Diego, USA, November 2010) [Details]
(2010)Gastroenterology 138:5 (Suppl1)
Brint, EK., O'Callaghan, G., Regan, T., Shanahan, F., Houston, A.; (2010) Synergy between Fas and TLR4 in promoting pro-inflammatory cytokine synthesis in macrophages and intestinal epithelial cells ¿ relevance to IBD Gastroenterology 138:5 (Suppl1) Digestive Diseases Week, New Orleans, [Details]
(2010)Society for Neuroscience (San Diego, USA, November 2010)
Cryan JF, Clarke G, Grenham S, Scully P, Shanahan F, Dinan TG (2010) The gut microbiome markedly influences hippocampal neurotransmission in the mouse: Role of gender Society for Neuroscience (San Diego, USA, November 2010) [Details]
(2010)Digestive Disease Week
Pruteanu, M; Hyland, NP; Clarke, D; Kiely, B; Shanahan, F; (2010) Bacterial proteolytic profile in inflammatory bowel diseases Digestive Disease Week [Details]
(2010)European Society of Gastrointestinal Radiology
O’Connor OJ, McSweeney SM, Mc Williams S, O’Regan K, Desmond A, Shanahan F, Quigley E, Maher MM. (2010) The use of diagnostic imaging in irritable bowel syndrome patients European Society of Gastrointestinal Radiology [Details]
(2009)Irish Society of Gastroenterology (ISG) Conference
Abu Shanab, A; Ahmeda, A; Murphy, E; OMahony, L; Bennett, M; Shanahan, F; Quigley, EMM (2009) Impact of small intestinal bacterial overgrowth (SIBO) on bacterial translocation and liver histology Irish Society of Gastroenterology (ISG) Conference Killarney- Ireland, Irish Society of Gastroenterology (ISG) Conference, [Details]
(2009)*
O'Connor, Aine and O'Sullivan, Aifric and Kaluskar, Soniya and Mion, Brian and Shanahan, Fergus and Marchesi, Julian and Gibney, Micheal and Cashman, Kevin and Flynn, Albert and Brennan, Lorraine; (2009) INVESTIGATING THE ABILITY OF LACTOBACILLUS SALIVARIUS UCC 118 TO MODULATE THE GUT MICROFLORA IN HEALTHY HUMANS * [Details]
(2009)INVESTIGATING THE EFFECTS OF VITMAIN D SUPPLEMENTATION ON METABOLIC HEALTH PARAMETERS IN HEALTHY ADULTS
OSullivan, AM,Brennan, L,Cashman, K,Flynn, A,Shanahan, F,Kaluskar, S,OConnor, A,Mion, B,Gibney, MJ (2009) ANNALS OF NUTRITION AND METABOLISM INVESTIGATING THE EFFECTS OF VITMAIN D SUPPLEMENTATION ON METABOLIC HEALTH PARAMETERS IN HEALTHY ADULTS , pp.439-440 [Details]
(2009)INVESTIGATING THE ABILITY OF LACTOBACILLUS SALIVARIUS UCC 118 TO MODULATE THE GUT MICROFLORA IN HEALTHY HUMANS
O'Connor, A,O'Sullivan, A,Kaluskar, S,Mion, B,Shanahan, F,Marchesi, J,Gibney, M,Cashman, K,Flynn, A,Brennan, L (2009) ANNALS OF NUTRITION AND METABOLISM INVESTIGATING THE ABILITY OF LACTOBACILLUS SALIVARIUS UCC 118 TO MODULATE THE GUT MICROFLORA IN HEALTHY HUMANS , pp.391-391 [Details]
(2009)Investigating the Effects of Vitmain D Supplementation on Metabolic Health Parameters in Healthy Adults
OSullivan, A. M.,Brennan, L.,Cashman, K.,Flynn, A.,Shanahan, F.,Kaluskar, S.,OConnor, A.,Mion, B.,Gibney, M. J. (2009) Investigating the Effects of Vitmain D Supplementation on Metabolic Health Parameters in Healthy Adults , pp.439-440439 Globe icon [Details]
(2009)Investigating the Ability of Lactobacillus Salivarius Ucc 118 to Modulate the Gut Microflora in Healthy Humans
O'Connor, A.,O'Sullivan, A.,Kaluskar, S.,Mion, B.,Shanahan, F.,Marchesi, J.,Gibney, M.,Cashman, K.,Flynn, A.,Brennan, L. (2009) Investigating the Ability of Lactobacillus Salivarius Ucc 118 to Modulate the Gut Microflora in Healthy Humans , pp.391-391391 Globe icon [Details]
(2009)DDW 2009; Gastroenterology
Hall, L. J.,Quinlan, A.,Shanahan, F.,Nally, K.,Melgar, S. (2009) Natural Killer Cell Responses in Both Acute and Chronic Phases of a Murine Model of Experimental Colitis DDW 2009; Gastroenterology Globe icon [Details]
(2009)DDW 2009; Gastroenterology
Moloney, G.,Corr, S.,Hall, L. J.,Murphy, C.,Quinlan, A.,Kruidenier, L.,Calver, A. R.,Mclean, P. G.,Lee, K.,Shanahan, F.,Nally, K.,Melgar, S. (2009) The Effect of the Farnesoid X Receptor (FXR) and It's Agonist-GSK488062B-On Experimental Models of Colitis and Cytokine Production from IBD Tissue DDW 2009; Gastroenterology Globe icon [Details]
(2008)BMC Gastroenterology
Murphy, C.,Moloney, G.,Casey, P.,Haynes, A. C.,Kruidenier, L.,Calver, A.,McLean, P.,Lee, K.,Hill, C.,O'Mahony, L.,Shanahan, F.,Nally, K. (2008) Modification of lymphocyte trafficking in an in vivo model of IBD following administration of a novel alpha 4 integrin antagonist BMC Gastroenterology Globe icon [Details]
(2008)DDW 2008; Gastroenterology
Docena, G. H.,Fanning, A.,Rovedatti, L.,Di Sabatino, A.,Leakey, N. A.,Knowles, C. H.,Lee, K.,Shanahan, F.,Nally, K.,McLean, P.,MacDonald, T. T.,Kruidenier, L. (2008) Activation and modulation of the MAP kinase pathway in IBD DDW 2008; Gastroenterology Globe icon [Details]
(2008)DDW 2008; Gastroenterology
Corr, S. C.,O'Hara, A.,O'Mahony, L.,Nally, K.,Shanahan, F.,Hill, C.,Gahan, C. G. (2008) Mechanism of epithelial CCL20 response to listeria DDW 2008; Gastroenterology Globe icon [Details]
(2008)Digestive Disease Week (San Diego, USA, May 2008)
Fitzgerald P, Clarke G, Scully P, Cryan JF, Shanahan F, Quigley EMM, Cassidy EM, Dinan TG (2008) Tryptophan catabolism in irritable bowel syndrome: Relationship to cytokines, severity and psychiatric comorbidity Digestive Disease Week (San Diego, USA, May 2008) [Details]
(2008)Gastroenterology 134:4 (Suppl 1)
Houston, A., O'Callaghan, G., Shanahan, F.; (2008) COX-derived PGE2 modulates FasL expression via the EP1 receptor in colon cancer cells Gastroenterology 134:4 (Suppl 1) [Details]
(2007)The Joint Meeting of the Society for Social Medicine & the International Epidemiological Association (European Federation)
Mc Carthy, Vera; Bairead, E.; Fitzgerald, A.P.; Shanahan, F.; Perry, Ivan J. ; (2007) Appendectomy, smoking and inflammatory bowel disease; a case control study The Joint Meeting of the Society for Social Medicine & the International Epidemiological Association (European Federation) University College Cork, , 12-SEP-07 - 14-SEP-07 [Details]
(2006)2nd Interdisciplinary Conference UCC
Mc Carthy, V., Bairead, E., Fitzgerald, A.P., Shanahan, F., and Perry, I.P.; (2006) Appendectomy, smoking and inflammatory bowel disease; a case control study 2nd Interdisciplinary Conference UCC University College Cork, [Details]
(2006)Appendectomy, smoking and inflammatory bowel disease; a case control study
Mc Carthy, V., Bairead, E., Fitzgerald, A.P., Shanahan, F., and Perry, I.P. ; (2006) 14th Annual Medical Faculty Research Day Appendectomy, smoking and inflammatory bowel disease; a case control study Cork, [Details]
(2006)DDW 2006; Gastroenterology
Nally, K.,O'Brien, D.,MacSharry, J.,Bairead, E.,O'Sullivan, G. C.,O'Connell, J.,Shanahan, F. (2006) IFN gamma and TNF alpha synergize to induce maximal NF-kappa B activation, NF-kappa B mediated trail expression and apoptosis of colonic epithelial cells DDW 2006; Gastroenterology Globe icon [Details]
(2006)14th Annual Medical Faculty Research Day, 2006
Mc Carthy, V., Bairead, E., Fitzgerald, A.P., Shanahan, F., and Perry, I.P. ; (2006) Appendectomy, smoking and inflammatory bowel disease; a case control study 14th Annual Medical Faculty Research Day, 2006 Cork, , 02-JAN-06 - 03-JAN-06 [Details]
(2004)DDW 2004; Gastroenterology
Nally, K.,O'Brien, D.,O'Connell, J.,Shanahan, F. (2004) Interferon gamma(IFN-gamma) selectively suppresses TNF-alpha-induced COX-1 and COX-2 expression in intestinal epithelial cells by inhibiting NF-kappa B function DDW 2004; Gastroenterology Globe icon [Details]
(2004)DDW 2004; Gastroenterology
Rosberg-Cody, E.,Ross, P.,Nally, K.,Anwar, M.,O'Mahony, L.,Ryan, A.,Hussey, S.,Murphy, B.,Fitzgerald, G.,Shanahan, F.,Stanton, C. (2004) Metabolic basis of host-flora interactions in the gut - Role of CLA DDW 2004; Gastroenterology Globe icon [Details]
(2003)Proceedings of the Nutrition Society Irish Section Annual Meeting 2003
McCarthy D, O¿Brien M, Kiely M, Shanahan F and Cashman KD.; (2003) Comparison of vitamin D intake and status and serum parathyroid hormone in patients with Crohn¿s disease and healthy sex-and age-matched control subjects . In: Cambridge University Press eds. Proceedings of the Nutrition Society Irish Section Annual Meeting 2003 [Details]
(2003)EULAR 2003 Annual European Congress of Rheumatology
O'Rourke, K.P.,O'Donoghue, G.,Adams, C.,Mulcahy, H.,Molloy, C.,Silke, C.,Shanahan, F.,Molloy, M.,O'Gara, F. ; (2003) The identification and significance of a polymorphism in the LT-Beta promoter in RA patients. Ann. Rheum. Dis. 62: Suppl. 1 EULAR 2003 Annual European Congress of Rheumatology Lisbon, Portugal, , pp.134-135 [Details]
(2003)American College of Rheumatology 67th Annual Scientific Meeting
O'Rourke, K.P., O'Donoghue, G., Adams, C., Mulcahy, H., Molloy, C., Silke, C., Molloy, M., Shanahan, F., and O'Gara, F.; (2003) Investigation of the role of Lymphotoxin-Beta and related molecules in the immunogenetics of rheumatoid arthritis. Arthritis Rheum. 48(9): Suppl. S American College of Rheumatology 67th Annual Scientific Meeting Orlando, Florida, USA, , 23-OCT-03 - 28-OCT-03 , pp.S58-S58 [Details]
(2003)EULAR 2003 Annual European Congress of Rheumatology
Molloy, C., Adams, C., O'Donoghue, G., Mulcahy, H., Busteed, S., O'Rourke, K., Silke, C., McDermott, M., Shanahan, F., Molloy, M.G., and O'Gara, F.; (2003) Polymorphisms at the lymphotoxin alpha promoter in rheumatoid arthritis. Ann. Rheum. Dis. 62: Suppl. 1 EULAR 2003 Annual European Congress of Rheumatology Lisbon, Portugal, , 18-JUN-03 - 21-JUN-03 , pp.366-366 [Details]
(2003)European League Against Rheumatism (EULAR) 2003 Annual European Congress of Rheumatology
O'Rourke, K.P., O'Donoghue, G., Adams, C., Mulcahy, H., Molloy, C., Silke, C., Shanahan, F., Molloy, M., and O'Gara, F. ; (2003) High levels of Lymphotoxin-Beta (LT-Beta) expression in rheumatoid arthritis patients synovium. Ann. Rheum. Dis. 62: Suppl. 1 European League Against Rheumatism (EULAR) 2003 Annual European Congress of Rheumatology Lisbon, Portugal, , 18-JUN-03 - 21-JUN-03 , pp.106-106 [Details]
(2001)DDW 2001; Gastroenterology
Nally, K.,O'Connell, J.,Morgan, J.,Collins, J. K.,O'Sullivan, G. C.,Shanahan, F. (2001) IGF-1 protects colonic epithelial cells from cytokine induced apoptosis by maintaining cellular phospho-tyrosine content and preventing cytochrome C release DDW 2001; Gastroenterology Globe icon [Details]
(2001)DDW 2001; Gastroenterology
Nally, K.,Kelly, R.,Ryan, P.,O'Connell, J.,O'Sullivan, G. C.,Morgan, J.,Shanahan, F. (2001) The chemopreventative agent N-acetyl-L-cysteine (NAC) decreases epidermal growth factor receptor (EGFR) levels on colonic carcinoma cell lines DDW 2001; Gastroenterology Globe icon [Details]
(2001)DDW 2001; Gastroenterology
Nally, K.,Mullan, B.,O'Connell, J.,Morgan, J.,Collins, J. K.,O'Sullivan, G. C.,Shanahan, F. (2001) Pro inflammatory cytokines suppress p53 function in colonic epithelial cells - A link between inflammation and tumorigenesis DDW 2001; Gastroenterology Globe icon [Details]
(2000)DDW 2000; Gastroenterology
Nally, K.,O'Connell, J.,Morgan, J.,O'Sullivan, G. C.,Collins, J. K.,Shanahan, F. L. (2000) Maximal activation of epithelial NFKB - An additional molecular mechanism underlying synergy between IFN-Gamma and TNF-Alpha DDW 2000; Gastroenterology Globe icon [Details]
(1999)DDW 1999; Gastroenterology
Nally, K.,O'Connell, J.,Morgan, J.,O'Sullivan, G. C.,Collins, J. K.,Shanahan, F. L. J. (1999) The commitment to die: Role of c-myc in lowering epithelial cell threshold for apoptosis by IFN-gamma and TNF-alpha DDW 1999; Gastroenterology Globe icon [Details]
(1999)Irish Journal of Medical Science
Bennett MW, Houston A, O'Connell J, O'Sullivan GC, Collins JK, Shanahan F (1999) Neutrophilic infiltration does not occur in FasL-expressing colonic carcinomas, irrespective of TGF-B1 expression Irish Journal of Medical Science [Details]
(1998)DDW 1998; Gastroenterology
Nally, K.,Newton, F.,O'Connell, J.,Morgan, J.,O'Sullivan, G. C.,Collins, J. K.,Shanahan, F. (1998) Epithelial cytoprotection is part of the therapeutic effect of interleukin-10 in mucosal inflammation DDW 1998; Gastroenterology Globe icon [Details]
(1997)DDW 1997; Gastroenterology
Winter, D. C.,Nally, K.,OCallaghan, J.,Matthews, J. B.,Harvey, B. J.,OSullivan, G. C.,Shanahan, F. (1997) Cytoskeletal disruption by jasplakinolide inhibits colon cancer growth in vitro DDW 1997; Gastroenterology Globe icon [Details]

Honours and Awards

 YearTitleAwarding Body
2011WIRM (World Immune Regulation Meeting V) Special Lecture: Death of a celebrity scientist. Davos, March 25, 2011 World Immune Regulation Meeting V, Davos, Switzerland.
201123rd Morton I. Grossman distinguished lectureship, American Gastroenterological Association DDW, McCormick Place, Chicago, May 8th, 2011 Mining Microbes for Mankind – from science to society. American Gastroenterology Association
2010DDW/AGA Presidential (Gail Hecht) Plenary Lecture: New Orleans, Monday May 3rd 2010 Microbiota in Digestive Health: promise, prospects and pragmatism. American Gastroenterology Association
2010Named in top 50 Irish and Irish Americans in Bioscience, Irish Voice Thursday, May 20, 2010 www.irishcentral.com/business/lists/life_science_50 www.irishcentral.com/business/lists/life_science_50
2010St. Luke’s Day Keynote Lecture, How doctors think: staying fresh in changing times. Royal College of Physicians of Ireland, to be delivered Nov 5th, 2010 Royal College of Physicians of Ireland
2009David Sun Lecture at the American College of Gastroenterology, San Diego, October 24th, 2009 Gut Microbes – from bugs to drugs American College of Gastroenterology
2008Schwabe-Walsh Lecture April 30th, 2008. University of California, Los Angeles. “Bioprospecting in the gut – from bugs to drugs”. University of California at Los Angeles
200825th Daniel Perey Public Lecture, McMaster University, Ontario, Canada, June 18th, 2008 Bioprospecting in the gut. McMaster University, Ontario, Canada.
2007President of the Irish Society of Gastroenterology, April 2007-2009 Irish Society of Gastroenterology
2006First prize (gastroenterology) BMA book awards 2006 for Fast Facts in IBD by Rampton D & Shanahan F. British Medical Association
2006Keynote speaker Broad Foundation annual scientific meeting, Los Angeles, March 2006 Broad Foundation
200536th annual Kushlan Lecture and visiting professorship Yale school of medicine, New Haven, Feb 2nd, 2005 "Making Microbes work for Mankind". Yale School of Medicine
2003Melrose Lecture at Royal College of Physicians & Surgeons, Glasgow 2003 Role of Bacteria in IBD Royal College of Physicians & Surgeons, Glasgow
2002State-of-the-Art Lecture, American Gastroenterological Association, DDW, San Francisco May 2002. “Cellular and Molecular Basis of Probiotic Effects in Intestinal Disorders” American Gastroenterological Association
2001State-of-the-Art Lecture, American Gastroenterological Association, DDW Atlanta May 2001. “Non-endoscopic diagnosis of inflammatory bowel disease” American Gastroenterological Association
2000Sidney Truelove Lecture. “Probiotics – treatment of the future”. Oxford Sept 11, 2000. ? Oxford University
2000UCLA Schwabe lecture ‘IBD – an internet of genes, bacteria and T cells.’ and Arthur D. Schwabe visiting lectureship, University of California at Los Angeles (UCLA), US, June 28th, 2000. University of California at Los Angeles (UCLA)
1999State-of-the-Art Lecture, American Gastroenterological Association, DDW Orlando May 1999. “Pathogenetic insights and new therapies in inflammatory bowel disease” American Gastroenterological Association
1998First De Pazzi lecture, Mercy Hospital, Cork April 6, 1998. The clinical investigator: an endangered species, alive and well in Cork. National University of Ireland Cork/Mercy University Hospital, Cork, Ireland.
1995The 35th Graves Lecture & Medal. Lecture title: Inflammatory bowel disease: from molecular mechanisms to new therapeutic strategies, Dublin. The Royal Academy of Medicine in Ireland and Health Research Board of Ireland
1993State-of-the-art Lecture & Medal, the Irish Society of Gastroenterology: Lecture title: 'Inflammatory bowel disease: modern concepts of pathogenesis & treatment', November 1993. Irish Society of Gastroenterology
1985AGA Research Training Award. (June/85-July/86) American Gastroenterological Association
1982Canadian Foundation for Ileitis/Colitis 'Promising Young Investigator' Award. 1982 Canadian Foundation for Ileitis/Colitis
1982Travelling Studentship in Medicine of National University of Ireland (1982-1984) National University of Ireland
1977Gold Medal in Medicine, Mater Misericordiae Hospital, Dublin, Ireland. Mater Misericordiae Hospital, Dublin, Ireland
1976Leonard Prize (Medicine), Mater Misericordiae Hospital, Dublin, Ireland Mater Misericordiae Hospital Dublin Ireland
1975First Place, Irish Inter-University Clinico-Pathology Competition (team member). National University of Ireland
1975Dillon Memorial Prize for Pharmacology & Therapeutics NUI, University College Dublin

Professional Associations

 AssociationFunctionFrom / To
Royal College of Physicians of the United Kingdom Fellow/
Royal College of Physicians of Ireland Fellow/
Western Society for Clinical Investigation Member/
American Federation for Clinical Research Member/
Royal Academy of Medicine in Ireland Fellow/
Society of Mucosal Immunology Fellow/
The Corrigan Club of Ireland Member/
Association of Physicians of Great Britain and Ireland Member/
Royal College of Physicians and Surgeons of Canada Fellow/
American College of Physicians Fellow/
Irish Society for Gastroenterology Member/
American Gastroenterology Association Fellow/
American Association for the Advancement of Science Member/
Clinical Immunology Society Member/
American Association of Immunologists Member/

Patents

 Patent NumberTitleInventorGranted
ALIM26/C/WO-PCTA product (Bifidobacterium). Collins JK, O’Sullivan GC, O’Mahony L, Shanahan F, Kiely B.01-JAN-11
ALIM25/C/WO-PCTA product (Lactobacillus paracasei). Collins JK, O’Sullivan GC, O’Mahony L, Shanahan F, Kiely B.01-JAN-11
ALIM24/C/WO-PCTA product (Lactobacillus salivarius). Collins JK, O’Sullivan GC, O’Mahony L, Shanahan F, Kiely B, Dunne C.01-JAN-11
ALIM01/C/WO-PCTA probiotic product. Collins JK, O’Sullivan GC, O’Mahony L, Shanahan F, Kiely B, Dunne C.01-JAN-11
ENT002/C/WO-PCTBifidobacterium in the treatment of inflammatory disease. Collins JK, O’Sullivan GC, O’Mahony L, Shanahan F.01-JAN-11
ENT001/C/WO-PCTUse of Lactobacillus salivarius. Collins JK, O’Sullivan GC, O’Mahony L, Shanahan F.01-JAN-11

Conference Contributions

YearPublication
(2014)37th European Cystic Fibrosis Conference,
O'Callaghan G, Ronan N, Houston A, Shanahan F and Plant B (2014) Modulation of Cystic Fibrosis gut inflammation - A pivotal role of the lung gut axis?. [Poster Presentation], 37th European Cystic Fibrosis Conference, Stockholm, Sweden . [Details]
(2014)37th European Cystic Fibrosis Conference,
O'Callaghan G, Ronan N, Houston A, Shanahan F and Plant B (2014) Modulation of Cystic Fibrosis gut inflammation - A pivotal role of the lung gut axis?. [Poster Presentation], 37th European Cystic Fibrosis Conference, Stockholm, Sweden . [Details]
(2014)National Cystic Fibrosis Conference,
O’Callaghan G, Houston A, Ronan N, Foley N, Shanahan F and Plant BJ (2014) Investigation of the interplay of the Cystic Fibrosis lung-gut axis in the regulation of inflammation of intestinal epithelial cells. [Poster Presentation], National Cystic Fibrosis Conference, Killarney . [Details]
(2014)National Cystic Fibrosis Conference,
O’Callaghan G, Houston A, Ronan N, Foley N, Shanahan F and Plant BJ (2014) Investigation of the interplay of the Cystic Fibrosis lung-gut axis in the regulation of inflammation of intestinal epithelial cells. [Poster Presentation], National Cystic Fibrosis Conference, Killarney . [Details]
(2013)Irish Association for Cancer Research,
O'Callaghan, GP., Reagan, M., Flores, L., Zhang, Y., Roccaro, A., Shanahan, F., Ghobrial, I., Houston, AM. (2013) Suppression of the Prostaglandin EP1 Receptor reduces Colon Cancer Cell Invasion and Metastasis. [Oral Presentation], Irish Association for Cancer Research, Dublin , 27-FEB-13 - 01-MAR-13. [Details]
(2013)Irish Association for Cancer Research,
O'Callaghan, GP., Reagan, M., Flores, L., Zhang, Y., Roccaro, A., Shanahan, F., Ghobrial, I., Houston, AM. (2013) Suppression of the Prostaglandin EP1 Receptor reduces Colon Cancer Cell Invasion and Metastasis. [Oral Presentation], Irish Association for Cancer Research, Dublin , 27-FEB-13 - 01-MAR-13. [Details]
(2013)Digestive Disease Week, Florida, USA, May 2013,
Kennedy PJ, Clarke G, Allen AP, Ann O’Neill A, Groeger JA, Quigley EM, Shanahan F , Cryan JF, Dinan TG (2013) A Prospective Assessment of Cognitive Performance in Irritable Bowel Syndrome Reveals Persistent Visuospatial Memory Deficits. [Poster Presentation], Digestive Disease Week, Florida, USA, May 2013, Florida, USA , 18-MAY-13 - 22-MAY-13. [Details]
(2013)British and Irish Gastroenterology (BIG) Spring Meeting, Belfast, April 2013,
Kennedy PJ, Clarke G, Allen AP, Ann O’Neill A, Groeger JA, Quigley EM, Shanahan F , Cryan JF, Dinan TG (2013) A Prospective Study of Cognitive Performance in Irritable Bowel Syndrome: Visuospatial Memory Deficits as a Stable Feature. [Poster Presentation], British and Irish Gastroenterology (BIG) Spring Meeting, Belfast, April 2013, Belfast , 11-APR-13 - 13-APR-13. [Details]
(2013)Digestive Disease Week, Florida, USA, May 2013,
Kennedy PJ, Clarke G, Allen AP, Ann O’Neill A, Groeger JA, Quigley EM, Shanahan F , Cryan JF, Dinan TG (2013) A Prospective Assessment of Cognitive Performance in Irritable Bowel Syndrome Reveals Persistent Visuospatial Memory Deficits. [Poster Presentation], Digestive Disease Week, Florida, USA, May 2013, Florida, USA , 18-MAY-13 - 22-MAY-13. [Details]
(2013)BioPIC 2013,
O' Callaghan G, Reagan M, Flores L, Azab K, Zhang Y, Roccaro A, Shanahan F, Ghobrial I and Houston A (2013) Investigation of the role of the EP1 receptor in colon cancer cell homing by in vivo confocal microscopy. [Poster Presentation], BioPIC 2013, Dublin , 25-MAR-13 - 27-MAR-13. [Details]
(2013)British and Irish Gastroenterology (BIG) Spring Meeting, Belfast, April 2013,
Kennedy PJ, Clarke G, Allen AP, Ann O’Neill A, Groeger JA, Quigley EM, Shanahan F , Cryan JF, Dinan TG (2013) A Prospective Study of Cognitive Performance in Irritable Bowel Syndrome: Visuospatial Memory Deficits as a Stable Feature. [Poster Presentation], British and Irish Gastroenterology (BIG) Spring Meeting, Belfast, April 2013, Belfast , 11-APR-13 - 13-APR-13. [Details]
(2013)HRB Clinical Research Facility Conference,
O'Callaghan G, Ryan A, Reagan M, Flores L, Azab K, Zhang Y, Neary P, Roccaro A, Shanahan F, Ghobrial I and Houston A (2013) The EP1 Receptor – a new therapeutic target in the fight against colon cancer?. [Poster Presentation], HRB Clinical Research Facility Conference, Cork , 13-JUN-13 - 13-JUN-13. [Details]
(2012)Digestive Disease Week, San Diego, USA, May 2012,
Clarke G, Grenham S, Scully P, Fitzgerald P, Moloney, RD, Shanahan F, Dinan TG, Cryan JF (2012) Regulation of Serotonergic Neurotransmission and Behaviour by the Brain-Gut-Microbiome Axis. [Poster Presentation], Digestive Disease Week, San Diego, USA, May 2012, San Diego , 19-MAY-12 - 22-MAY-12. [Details]
(2012)Digestive Disease Week, San Diego, USA, May 2012,
Kennedy PJ, Clarke G, O’Neill A, Groeger JA, Quigley EM, Shanahan F , Cryan JF, Dinan TG (2012) Are deficits in episodic memory stress-related and mediated by tryptophan metabolism along the kynurenine pathway?. [Poster Presentation], Digestive Disease Week, San Diego, USA, May 2012, San Diego , 19-MAY-12 - 22-MAY-12. [Details]
(2013)BioPIC 2013,
O' Callaghan G, Reagan M, Flores L, Azab K, Zhang Y, Roccaro A, Shanahan F, Ghobrial I and Houston A (2013) Investigation of the role of the EP1 receptor in colon cancer cell homing by in vivo confocal microscopy. [Poster Presentation], BioPIC 2013, Dublin , 25-MAR-13 - 27-MAR-13. [Details]
(2011)RSNA 2011 Chicago USA..Education Exhibits (Poster),
Siobhan O' Neill MBBCh, Micheal Breen MBBCh MRCPI, Sara Anne Hayes MBBCh, Kevin Murphy MBBCh MRCS, Jackie Bye BA, Fergus Shanahan, Michael Maher (2011) Pictorial Review of the Use of Ultra Low-Dose CT of Abdomen and Pelvis in Patients with Crohns Disease: How Low Can We Go?. [Conference Organising Committee Chairperson], RSNA 2011 Chicago USA..Education Exhibits (Poster), Chicago, USA , 26-NOV-11 - 02-DEC-11. [Details]
(2011)RSNA 2011 Chicago USA..Education Exhibits (Poster),
Siobhan O' Neill MBBCh, Sebastian McWilliams BSc, Micheal Breen MBBCh, MRCPI , Fiona O'Neill, Jackie Bye BA, Anne Marie McGarrigle FRCR, BEng , Fergus Shanahan, Michael Maher (2011) The Effect of Statistical Iterative Image Reconstruction on Diagnostic Quality and Noise Indices for Low-dose CT: Establishing the Optimum Level of Iterative Reconstruction to Apply. [Conference Organising Committee Chairperson], RSNA 2011 Chicago USA..Education Exhibits (Poster), Chicago, USA , 26-NOV-11 - 02-DEC-11. [Details]
(2013)HRB Clinical Research Facility Conference,
O'Callaghan G, Ryan A, Reagan M, Flores L, Azab K, Zhang Y, Neary P, Roccaro A, Shanahan F, Ghobrial I and Houston A (2013) The EP1 Receptor – a new therapeutic target in the fight against colon cancer?. [Poster Presentation], HRB Clinical Research Facility Conference, Cork , 13-JUN-13 - 13-JUN-13. [Details]
(2010)Keystone Symposium: Innate Immunity: Mechanisms Linking with Adaptive Immunity,
Houston, A., Regan, T., O'Callaghan, G., Shanahan, F., Brint, EK.; (2010) Interplay between Fas and TLR signalling- regulation of inflammation in the gastrointestinal tract ?. [Poster Presentation], Keystone Symposium: Innate Immunity: Mechanisms Linking with Adaptive Immunity, Dublin , 07-JUN-10 - 12-JUN-10. [Details]
(2012)Digestive Disease Week, San Diego, USA, May 2012,
Clarke G, Grenham S, Scully P, Fitzgerald P, Moloney, RD, Shanahan F, Dinan TG, Cryan JF (2012) Regulation of Serotonergic Neurotransmission and Behaviour by the Brain-Gut-Microbiome Axis. [Poster Presentation], Digestive Disease Week, San Diego, USA, May 2012, San Diego , 19-MAY-12 - 22-MAY-12. [Details]
(2010)Digestive Diseases Week, 2010,
Brint E., O'Callaghan GP., Regan T., Shanahan F., Houston A.; (2010) Synergy between Fas and TLR4 in promoting pro-inflammatory cytokine synthesis in macrophages and intestinal epithelial cells - relevance to IBD. [Poster Presentation], Digestive Diseases Week, 2010, New Orleans , 02-MAY-10 - 05-MAY-10. [Details]
(2010)Microbes and Health Sackler Colloquium,
Claesson MJ; Cusack S; O'Sullivan O; Greene-Diniz R; de Weerd H; Flannery E; Marchesi JR; Falush D; Dinan T; Fitzgerald G; Stanton C; van Sinderen D; O'Connor M; Harnedy N; O'Connor K; Henry C; O'Mahony D; Fitzgerald AP; Shanahan F; Twomey C; Hill C; Ross RP; O'Toole PW (2010) Composition, variability, and temporal stability of the intestinal microbiota of the elderly. [Oral Presentation], Microbes and Health Sackler Colloquium, USA , 01-SEP-10 - 01-SEP-10. [Details]
(2012)Digestive Disease Week, San Diego, USA, May 2012,
Kennedy PJ, Clarke G, O’Neill A, Groeger JA, Quigley EM, Shanahan F , Cryan JF, Dinan TG (2012) Are deficits in episodic memory stress-related and mediated by tryptophan metabolism along the kynurenine pathway?. [Poster Presentation], Digestive Disease Week, San Diego, USA, May 2012, San Diego , 19-MAY-12 - 22-MAY-12. [Details]
(2010)European Society of Gastrointestinal Radiology,
O ‘Connor OJ, McWilliams S, O’Regan K, Desmond, Ni Laoire A, McLaughlin P, Shanahan F, Quigley E, Maher MM. (2010) Quantification of intra-abdominal gas volume in patients with functional gastro-intestinal disorder using CT. [Poster Presentation], European Society of Gastrointestinal Radiology, Dresden , 02-JUN-10 - 05-JUN-10. [Details]
(2011)RSNA 2011 Chicago USA..Education Exhibits (Poster),
Siobhan O' Neill MBBCh, Micheal Breen MBBCh MRCPI, Sara Anne Hayes MBBCh, Kevin Murphy MBBCh MRCS, Jackie Bye BA, Fergus Shanahan, Michael Maher (2011) Pictorial Review of the Use of Ultra Low-Dose CT of Abdomen and Pelvis in Patients with Crohns Disease: How Low Can We Go?. [Conference Organising Committee Chairperson], RSNA 2011 Chicago USA..Education Exhibits (Poster), Chicago, USA , 26-NOV-11 - 02-DEC-11. [Details]
(2010)European Congress of Radiology,
O’Connor OJ, McSweeney SM, O’Regan K, Desmond A, Shanahan F, Quigley E, Maher MM. (2010) The use of diagnostic imaging in irritable bowel syndrome patients. [Oral Presentation], European Congress of Radiology, Vienna , 04-MAR-10 - 08-MAR-10. [Details]
(2010)European Society of Gastrointestinal Radiology,
O’Connor OJ, McSweeney SM, O’Regan K, Desmond A, Shanahan F, Quigley E, Maher MM. (2010) The use of diagnostic imaging in irritable bowel syndrome patients. [Oral Presentation], European Society of Gastrointestinal Radiology, Dresden , 02-JUN-10 - 05-JUN-10. [Details]
(2011)RSNA 2011 Chicago USA..Education Exhibits (Poster),
Siobhan O' Neill MBBCh, Sebastian McWilliams BSc, Micheal Breen MBBCh, MRCPI , Fiona O'Neill, Jackie Bye BA, Anne Marie McGarrigle FRCR, BEng , Fergus Shanahan, Michael Maher (2011) The Effect of Statistical Iterative Image Reconstruction on Diagnostic Quality and Noise Indices for Low-dose CT: Establishing the Optimum Level of Iterative Reconstruction to Apply. [Conference Organising Committee Chairperson], RSNA 2011 Chicago USA..Education Exhibits (Poster), Chicago, USA , 26-NOV-11 - 02-DEC-11. [Details]
(2010)Health and Medicine Research Day, Brookfield, Cork, June 2010,
Scully P, Clarke G, Grenham S, Fitzgerald P, O’Mahony CM,McKernan DP,Tramullas M,Shanahan F, Dinan TG, & Cryan JF (2010) Gender-Dependent Influence of the Gut Microbiome on the Hippocampal 5-HT System. [Poster Presentation], Health and Medicine Research Day, Brookfield, Cork, June 2010, Cork , 16-JUN-10 - 16-JUN-10. [Details]
(2010)Keystone Symposium: Innate Immunity: Mechanisms Linking with Adaptive Immunity,
Houston, A., Regan, T., O'Callaghan, G., Shanahan, F., Brint, EK.; (2010) Interplay between Fas and TLR signalling- regulation of inflammation in the gastrointestinal tract ?. [Poster Presentation], Keystone Symposium: Innate Immunity: Mechanisms Linking with Adaptive Immunity, Dublin , 07-JUN-10 - 12-JUN-10. [Details]
(2010)Psychoneuroimmunology Research Society, Trinity College, Dublin, June 2010,
Scully P, Clarke G, Grenham S, Fitzgerald P, O’Mahony CM, ,McKernan DP,Tramullas M,Shanahan F, Dinan TG, & Cryan JF (2010) Gender-Dependent Influence of the Gut Microbiome on the Hippocampal 5-HT System. [Poster Presentation], Psychoneuroimmunology Research Society, Trinity College, Dublin, June 2010, Dublin , 02-JUN-10 - 05-JUN-10. [Details]
(2010)Digestive Diseases Week, 2010,
Brint E., O'Callaghan GP., Regan T., Shanahan F., Houston A.; (2010) Synergy between Fas and TLR4 in promoting pro-inflammatory cytokine synthesis in macrophages and intestinal epithelial cells - relevance to IBD. [Poster Presentation], Digestive Diseases Week, 2010, New Orleans , 02-MAY-10 - 05-MAY-10. [Details]
(2010)Society for Neuroscience, San Diego, USA, November 2010,
Cryan JF, Clarke G, Grenham S, Scully P, Shanahan F, Dinan TG (2010) The gut microbiome markedly influences hippocampal neurotransmission in the mouse: Role of gender. [Poster Presentation], Society for Neuroscience, San Diego, USA, November 2010, San Diego , 13-NOV-10 - 17-NOV-10. [Details]
(2010)Society for Neuroscience, San Diego, USA, November 2010,
Tramullas M, Clarke G, Shanahan F, Dinan TG, Cryan JF (2010) The gut microbiome alters toll-like receptor and cytokine expression levels in the spinal cord: Role of gender. [Poster Presentation], Society for Neuroscience, San Diego, USA, November 2010, San Diego , 13-NOV-10 - 17-NOV-10. [Details]
(2010)Microbes and Health Sackler Colloquium,
Claesson MJ; Cusack S; O'Sullivan O; Greene-Diniz R; de Weerd H; Flannery E; Marchesi JR; Falush D; Dinan T; Fitzgerald G; Stanton C; van Sinderen D; O'Connor M; Harnedy N; O'Connor K; Henry C; O'Mahony D; Fitzgerald AP; Shanahan F; Twomey C; Hill C; Ross RP; O'Toole PW (2010) Composition, variability, and temporal stability of the intestinal microbiota of the elderly. [Oral Presentation], Microbes and Health Sackler Colloquium, USA , 01-SEP-10 - 01-SEP-10. [Details]
(2008)International Society for the Study of Behavioural Development,
Veale, A., & Shanahan, F. (2008) Inversing the lens: the challenge to communities of the reintegration of formerly abducted girl mothers. [Oral Presentation], International Society for the Study of Behavioural Development, Würzburg, Germany , 01-JAN-08 - 01-JAN-08. [Details]
(2008)ECR Vienna,
O¿Regan K, Desmond A, Ni Churrain C, McWilliams S, McSweeney S, Shanahan F, Maher M.; (2008) Radiation exposure in patients with inflammatory bowel disease. Current status and future directions. [Oral Presentation], ECR Vienna, ECR Vienna , 01-MAR-08 - 01-MAR-08. [Details]
(2010)European Society of Gastrointestinal Radiology,
O ‘Connor OJ, McWilliams S, O’Regan K, Desmond, Ni Laoire A, McLaughlin P, Shanahan F, Quigley E, Maher MM. (2010) Quantification of intra-abdominal gas volume in patients with functional gastro-intestinal disorder using CT. [Poster Presentation], European Society of Gastrointestinal Radiology, Dresden , 02-JUN-10 - 05-JUN-10. [Details]
(2008)Digestive Disease Week, San Diego, USA, May 2008,
Fitzgerald P, Clarke G, Scully P, Cryan JF, Shanahan F, Quigley EMM, Cassidy EM, Dinan TG (2008) Tryptophan catabolism in irritable bowel syndrome: Relationship to cytokines, severity and psychiatric comorbidity. [Poster Presentation], Digestive Disease Week, San Diego, USA, May 2008, San Diego , 17-MAY-08 - 22-MAY-08. [Details]
(2010)European Congress of Radiology,
O’Connor OJ, McSweeney SM, O’Regan K, Desmond A, Shanahan F, Quigley E, Maher MM. (2010) The use of diagnostic imaging in irritable bowel syndrome patients. [Oral Presentation], European Congress of Radiology, Vienna , 04-MAR-10 - 08-MAR-10. [Details]
(2008)COX-derived PGE2 modulates FasL expression via the EP1 receptor in colon cancer cells,
Houston A., O'Callaghan G., Shanahan F.; (2008) COX-derived PGE2 modulates FasL expression via the EP1 receptor in colon cancer cells, . [Details]
(2008)Digestive Disease Week, 2008,
Houston, A., O'Callaghan, G., Shanahan, F.; (2008) COX-derived PGE2 modulates FasL expression via the EP1 receptor in colon cancer cells. [Poster Presentation], Digestive Disease Week, 2008, San Diego , 17-MAY-08 - 22-MAY-08. [Details]
(2010)European Society of Gastrointestinal Radiology,
O’Connor OJ, McSweeney SM, O’Regan K, Desmond A, Shanahan F, Quigley E, Maher MM. (2010) The use of diagnostic imaging in irritable bowel syndrome patients. [Oral Presentation], European Society of Gastrointestinal Radiology, Dresden , 02-JUN-10 - 05-JUN-10. [Details]
(2007)Tumor-expressed Fas ligand and its role in the pathogenesis of colon cancer,
Ryan A., O'Connell J., Shanahan F., Houston A.; (2007) Tumor-expressed Fas ligand and its role in the pathogenesis of colon cancer, . [Details]
(2007)Regulation of Fas ligand expression in colon cancer by the cyclooxygenase signaling pathway,
Houston A., Shanahan F.; (2007) Regulation of Fas ligand expression in colon cancer by the cyclooxygenase signaling pathway, . [Details]
(2010)Health and Medicine Research Day, Brookfield, Cork, June 2010,
Scully P, Clarke G, Grenham S, Fitzgerald P, O’Mahony CM,McKernan DP,Tramullas M,Shanahan F, Dinan TG, & Cryan JF (2010) Gender-Dependent Influence of the Gut Microbiome on the Hippocampal 5-HT System. [Poster Presentation], Health and Medicine Research Day, Brookfield, Cork, June 2010, Cork , 16-JUN-10 - 16-JUN-10. [Details]
(2007)Irish Society of Gastroenterology Winter Meeting,
Houston, A., O'Callaghan, G., O'Connell, J., Shanahan, F.; (2007) Involvement of COX and PGE2 in Fas ligand (FasL) expression by colon tumor cells. [Poster Presentation], Irish Society of Gastroenterology Winter Meeting, Dublin , 29-NOV-07 - 30-NOV-07. [Details]
(2010)Psychoneuroimmunology Research Society, Trinity College, Dublin, June 2010,
Scully P, Clarke G, Grenham S, Fitzgerald P, O’Mahony CM, ,McKernan DP,Tramullas M,Shanahan F, Dinan TG, & Cryan JF (2010) Gender-Dependent Influence of the Gut Microbiome on the Hippocampal 5-HT System. [Poster Presentation], Psychoneuroimmunology Research Society, Trinity College, Dublin, June 2010, Dublin , 02-JUN-10 - 05-JUN-10. [Details]
(2006)2nd Interdisciplinary Conference UCC, 2006, University College Cork,
Mc Carthy, V., Bairead, E., Fitzgerald, A.P., Shanahan, F., and Perry, I.P. (2006) Appendectomy, smoking and inflammatory bowel disease; a case control study. [Oral Presentation], 2nd Interdisciplinary Conference UCC, 2006, University College Cork, University College Cork , 17-NOV-06 - 17-NOV-06. [Details]
(2006)Irish Association for Cancer research,
Ryan, A., Shanahan, F., O'Connell, J., Houston, A.; (2006) Addressing the Fas Counterattack Controversy: Fas Ligand Promotes Tumor Immune Evasion Of Colon Cancer in vivo. [Poster Presentation], Irish Association for Cancer research, Galway , 03-MAR-06 - 04-MAR-06. [Details]
(2010)Society for Neuroscience, San Diego, USA, November 2010,
Cryan JF, Clarke G, Grenham S, Scully P, Shanahan F, Dinan TG (2010) The gut microbiome markedly influences hippocampal neurotransmission in the mouse: Role of gender. [Poster Presentation], Society for Neuroscience, San Diego, USA, November 2010, San Diego , 13-NOV-10 - 17-NOV-10. [Details]
(2006)Annual Scientific Meeting, Faculty of Radiologists, RCSI,
O’Connor OJ, O’Flynn S, Lynch S, SpenceL, Ryan M, Kelly M, Barry J, Fitzgerald E, MacEneaney P, O’Donovan N, Kenny B, O' Brien P, O’Leary P, Quigley E, Shanahan F, Maher MM. (2006) Assessing competence in interpretation of Imaging studies during Final Medical Examination: Experience from University College Cork (UCC). [Oral Presentation], Annual Scientific Meeting, Faculty of Radiologists, RCSI, Dublin , 30-SEP-06 - 28-SEP-06. [Details]
(2010)Society for Neuroscience, San Diego, USA, November 2010,
Tramullas M, Clarke G, Shanahan F, Dinan TG, Cryan JF (2010) The gut microbiome alters toll-like receptor and cytokine expression levels in the spinal cord: Role of gender. [Poster Presentation], Society for Neuroscience, San Diego, USA, November 2010, San Diego , 13-NOV-10 - 17-NOV-10. [Details]
(2005)Resolving the 'Fas counterattack' controversy: Fas ligand promotes tumor immune evasion of colon cancer in vivo,
Ryan AE., Shanahan F., O'Connell J., Houston AM.; (2005) Resolving the 'Fas counterattack' controversy: Fas ligand promotes tumor immune evasion of colon cancer in vivo, . [Details]
(2005)Irish Society of Gastroenterology,
Ryan, A., Shanahan, F., O'Connell, J., Houston, A.; (2005) Resolving the Fas Counterattack Controversy: Fas ligand promotes tumour immune evasion of colon cancer in vivo. [Oral Presentation], Irish Society of Gastroenterology, Limerick , 10-JUN-05 - 10-JUN-05. [Details]
(2008)International Society for the Study of Behavioural Development,
Veale, A., & Shanahan, F. (2008) Inversing the lens: the challenge to communities of the reintegration of formerly abducted girl mothers. [Oral Presentation], International Society for the Study of Behavioural Development, Würzburg, Germany , 01-JAN-08 - 01-JAN-08. [Details]
(2003)*,
O'Riordan, A., Shanahan, F., Morgan, JG; (2003) Analysis of the Expression of Inflammatory Cytokines over time in IL 10 knockout mice. [Oral Presentation], *, Trinity College Dublin , 01-OCT-03 - 01-OCT-03. [Details]
(2001)Fas Ligand expressed in colon cancer is associated with suppression of activation and IL-2 production in tumor-infiltrating T-cells,
Houston, A and Bennett, MW and O'Sullivan, GC and Shanahan, F and O'Connell, J; (2001) Fas Ligand expressed in colon cancer is associated with suppression of activation and IL-2 production in tumor-infiltrating T-cells. Fas Ligand expressed in colon cancer is associated with suppression of activation and IL-2 production in tumor-infiltrating T-cells, * , 01-DEC-02 - 01-DEC-01. [Details]
(2008)ECR Vienna,
O¿Regan K, Desmond A, Ni Churrain C, McWilliams S, McSweeney S, Shanahan F, Maher M.; (2008) Radiation exposure in patients with inflammatory bowel disease. Current status and future directions. [Oral Presentation], ECR Vienna, ECR Vienna , 01-MAR-08 - 01-MAR-08. [Details]
(2001)Interferon-gamma decreases interleukin-8 production in the alveolar epithelium by decreasing neurokinin-1 receptor expression,
O'Connor, TM and O'Connell, J and Houston, AM and Goode, T and Shanahan, F and Bredin, CP; (2001) Interferon-gamma decreases interleukin-8 production in the alveolar epithelium by decreasing neurokinin-1 receptor expression, . [Details]
(2000)Fas ligand mediates immune privilege and not neutrophil recruitment in colon cancer in vivo,
Houston A., Waldron-Lynch F., Bennett MW., Roche D., O'Sullivan GC., Collins JK., Shanahan F., O'Connell J.; (2000) Fas ligand mediates immune privilege and not neutrophil recruitment in colon cancer in vivo, . [Details]
(2008)Digestive Disease Week, San Diego, USA, May 2008,
Fitzgerald P, Clarke G, Scully P, Cryan JF, Shanahan F, Quigley EMM, Cassidy EM, Dinan TG (2008) Tryptophan catabolism in irritable bowel syndrome: Relationship to cytokines, severity and psychiatric comorbidity. [Poster Presentation], Digestive Disease Week, San Diego, USA, May 2008, San Diego , 17-MAY-08 - 22-MAY-08. [Details]
(2000)Neutrophilic infiltration does not occur in FasL-expressing human colonic carcinomas, irrespective of TGF-B1 expression,
Bennett MW., Houston A., O'Connell J., O'Sullivan GC., Collins JK., Shanahan F.; (2000) Neutrophilic infiltration does not occur in FasL-expressing human colonic carcinomas, irrespective of TGF-B1 expression, . [Details]
(2008)COX-derived PGE2 modulates FasL expression via the EP1 receptor in colon cancer cells,
Houston A., O'Callaghan G., Shanahan F.; (2008) COX-derived PGE2 modulates FasL expression via the EP1 receptor in colon cancer cells, . [Details]
(1997)Annual Medical Research Day, Cork University Hospital,
Waldron-Lynch, F., Adams, C., Shanahan, F., Molloy, M.G., and O'Gara, F.; (1997) Immunogenetics of Rheumatoid Arthritis (RA): Molecular characterisation of Tumour Necrosis Factor regulatory domains in RA patients. [Oral Presentation], Annual Medical Research Day, Cork University Hospital, Cork (IE) , 04-JUN-97 - 04-JUN-97. [Details]
(1996)6th International Tumour Necrosis Factor (TNF) Congress,
Waldron-Lynch, F., Adams, C., Mulcahy, B., McDermott, M.F., Amos, C.I., Shanahan, F., Molloy, M.G., and O'Gara, F.; (1996) Genetic analysis of the tumour necrosis factor - lymphotoxin (TNF-LT) region influencing susceptibility to rheumatoid arthritis. [Poster Presentation], 6th International Tumour Necrosis Factor (TNF) Congress, Rhodes (GR) , 08-MAY-96 - 12-MAY-96. [Details]
(2008)Digestive Disease Week, 2008,
Houston, A., O'Callaghan, G., Shanahan, F.; (2008) COX-derived PGE2 modulates FasL expression via the EP1 receptor in colon cancer cells. [Poster Presentation], Digestive Disease Week, 2008, San Diego , 17-MAY-08 - 22-MAY-08. [Details]
(1996)New Frontiers in Rheumatoid Arthritis (RA) Meeting, University of Manchester,
Waldron-Lynch, F., Adams, C., Mulcahy, B., McDermott, M.F., Amos, C.I., Shanahan, F., Molloy, M.G., and O'Gara, F.; (1996) Genetic analysis of the tumour necrosis factor - lymphotoxin (TNF-LT) region influencing susceptibility to rheumatoid arthritis. [Poster Presentation], New Frontiers in Rheumatoid Arthritis (RA) Meeting, University of Manchester, Manchester (UK) , 13-MAR-96 - 15-MAR-96. [Details]
(2007)Tumor-expressed Fas ligand and its role in the pathogenesis of colon cancer,
Ryan A., O'Connell J., Shanahan F., Houston A.; (2007) Tumor-expressed Fas ligand and its role in the pathogenesis of colon cancer, . [Details]
(1995)Irish Society of Rheumatology Spring Meeting,
Mulcahy, B., Adams, C., Waldron-Lynch, F., Stone, M., Phelan, M., Shanahan, F., Molloy, M., and O'Gara, F.; (1995) Irish multiplex RA families - TNF microsatellite analysis. [Oral Presentation], Irish Society of Rheumatology Spring Meeting, South Infirmary Hospital, Cork (IE) , 24-MAR-95 - 24-MAR-95. [Details]
(1995)Annual Research Day, Cork University Hospital,
Waldron-Lynch, F., Mulcahy, B., McDermott, M., Adams, C., Stone, M., Shanahan, F., Phelan, M., Molloy, M., and O'Gara, F.; (1995) Molecular genetics of Rheumatoid Arthritis (RA): microsatellite analysis of the TNF-LT locus in multiplex RA families. [Oral Presentation], Annual Research Day, Cork University Hospital, Cork (IE) , 07-JUN-95 - 07-JUN-95. [Details]
(1995)6th ISDE World Congress,
O'Sullivan, G.; Shanahan, F.; O'Mahony, A.; Collins, D.; Collins, J. K.; (1995) *. [N/A], 6th ISDE World Congress, Local Immune Suppression As a Growth and Metastatic Advantage for Human Oesophageal Squamous Cancers , 01-JAN-95 - 30-DEC-99. [Details]
(2007)Regulation of Fas ligand expression in colon cancer by the cyclooxygenase signaling pathway,
Houston A., Shanahan F.; (2007) Regulation of Fas ligand expression in colon cancer by the cyclooxygenase signaling pathway, . [Details]
(2007)Irish Society of Gastroenterology Winter Meeting,
Houston, A., O'Callaghan, G., O'Connell, J., Shanahan, F.; (2007) Involvement of COX and PGE2 in Fas ligand (FasL) expression by colon tumor cells. [Poster Presentation], Irish Society of Gastroenterology Winter Meeting, Dublin , 29-NOV-07 - 30-NOV-07. [Details]
(2006)2nd Interdisciplinary Conference UCC, 2006, University College Cork,
Mc Carthy, V., Bairead, E., Fitzgerald, A.P., Shanahan, F., and Perry, I.P. (2006) Appendectomy, smoking and inflammatory bowel disease; a case control study. [Oral Presentation], 2nd Interdisciplinary Conference UCC, 2006, University College Cork, University College Cork , 17-NOV-06 - 17-NOV-06. [Details]
(2006)Irish Association for Cancer research,
Ryan, A., Shanahan, F., O'Connell, J., Houston, A.; (2006) Addressing the Fas Counterattack Controversy: Fas Ligand Promotes Tumor Immune Evasion Of Colon Cancer in vivo. [Poster Presentation], Irish Association for Cancer research, Galway , 03-MAR-06 - 04-MAR-06. [Details]
(2006)Annual Scientific Meeting, Faculty of Radiologists, RCSI,
O’Connor OJ, O’Flynn S, Lynch S, SpenceL, Ryan M, Kelly M, Barry J, Fitzgerald E, MacEneaney P, O’Donovan N, Kenny B, O' Brien P, O’Leary P, Quigley E, Shanahan F, Maher MM. (2006) Assessing competence in interpretation of Imaging studies during Final Medical Examination: Experience from University College Cork (UCC). [Oral Presentation], Annual Scientific Meeting, Faculty of Radiologists, RCSI, Dublin , 30-SEP-06 - 28-SEP-06. [Details]
(2005)Resolving the 'Fas counterattack' controversy: Fas ligand promotes tumor immune evasion of colon cancer in vivo,
Ryan AE., Shanahan F., O'Connell J., Houston AM.; (2005) Resolving the 'Fas counterattack' controversy: Fas ligand promotes tumor immune evasion of colon cancer in vivo, . [Details]
(2005)Irish Society of Gastroenterology,
Ryan, A., Shanahan, F., O'Connell, J., Houston, A.; (2005) Resolving the Fas Counterattack Controversy: Fas ligand promotes tumour immune evasion of colon cancer in vivo. [Oral Presentation], Irish Society of Gastroenterology, Limerick , 10-JUN-05 - 10-JUN-05. [Details]
(2003)*,
O'Riordan, A., Shanahan, F., Morgan, JG; (2003) Analysis of the Expression of Inflammatory Cytokines over time in IL 10 knockout mice. [Oral Presentation], *, Trinity College Dublin , 01-OCT-03 - 01-OCT-03. [Details]
(2001)Fas Ligand expressed in colon cancer is associated with suppression of activation and IL-2 production in tumor-infiltrating T-cells,
Houston, A and Bennett, MW and O'Sullivan, GC and Shanahan, F and O'Connell, J; (2001) Fas Ligand expressed in colon cancer is associated with suppression of activation and IL-2 production in tumor-infiltrating T-cells. Fas Ligand expressed in colon cancer is associated with suppression of activation and IL-2 production in tumor-infiltrating T-cells, * , 01-DEC-02 - 01-DEC-01. [Details]
(2001)Interferon-gamma decreases interleukin-8 production in the alveolar epithelium by decreasing neurokinin-1 receptor expression,
O'Connor, TM and O'Connell, J and Houston, AM and Goode, T and Shanahan, F and Bredin, CP; (2001) Interferon-gamma decreases interleukin-8 production in the alveolar epithelium by decreasing neurokinin-1 receptor expression, . [Details]
(2000)Fas ligand mediates immune privilege and not neutrophil recruitment in colon cancer in vivo,
Houston A., Waldron-Lynch F., Bennett MW., Roche D., O'Sullivan GC., Collins JK., Shanahan F., O'Connell J.; (2000) Fas ligand mediates immune privilege and not neutrophil recruitment in colon cancer in vivo, . [Details]
(2000)Neutrophilic infiltration does not occur in FasL-expressing human colonic carcinomas, irrespective of TGF-B1 expression,
Bennett MW., Houston A., O'Connell J., O'Sullivan GC., Collins JK., Shanahan F.; (2000) Neutrophilic infiltration does not occur in FasL-expressing human colonic carcinomas, irrespective of TGF-B1 expression, . [Details]
(1997)Annual Medical Research Day, Cork University Hospital,
Waldron-Lynch, F., Adams, C., Shanahan, F., Molloy, M.G., and O'Gara, F.; (1997) Immunogenetics of Rheumatoid Arthritis (RA): Molecular characterisation of Tumour Necrosis Factor regulatory domains in RA patients. [Oral Presentation], Annual Medical Research Day, Cork University Hospital, Cork (IE) , 04-JUN-97 - 04-JUN-97. [Details]
(1996)6th International Tumour Necrosis Factor (TNF) Congress,
Waldron-Lynch, F., Adams, C., Mulcahy, B., McDermott, M.F., Amos, C.I., Shanahan, F., Molloy, M.G., and O'Gara, F.; (1996) Genetic analysis of the tumour necrosis factor - lymphotoxin (TNF-LT) region influencing susceptibility to rheumatoid arthritis. [Poster Presentation], 6th International Tumour Necrosis Factor (TNF) Congress, Rhodes (GR) , 08-MAY-96 - 12-MAY-96. [Details]
(1996)New Frontiers in Rheumatoid Arthritis (RA) Meeting, University of Manchester,
Waldron-Lynch, F., Adams, C., Mulcahy, B., McDermott, M.F., Amos, C.I., Shanahan, F., Molloy, M.G., and O'Gara, F.; (1996) Genetic analysis of the tumour necrosis factor - lymphotoxin (TNF-LT) region influencing susceptibility to rheumatoid arthritis. [Poster Presentation], New Frontiers in Rheumatoid Arthritis (RA) Meeting, University of Manchester, Manchester (UK) , 13-MAR-96 - 15-MAR-96. [Details]
(1995)Irish Society of Rheumatology Spring Meeting,
Mulcahy, B., Adams, C., Waldron-Lynch, F., Stone, M., Phelan, M., Shanahan, F., Molloy, M., and O'Gara, F.; (1995) Irish multiplex RA families - TNF microsatellite analysis. [Oral Presentation], Irish Society of Rheumatology Spring Meeting, South Infirmary Hospital, Cork (IE) , 24-MAR-95 - 24-MAR-95. [Details]
(1995)Annual Research Day, Cork University Hospital,
Waldron-Lynch, F., Mulcahy, B., McDermott, M., Adams, C., Stone, M., Shanahan, F., Phelan, M., Molloy, M., and O'Gara, F.; (1995) Molecular genetics of Rheumatoid Arthritis (RA): microsatellite analysis of the TNF-LT locus in multiplex RA families. [Oral Presentation], Annual Research Day, Cork University Hospital, Cork (IE) , 07-JUN-95 - 07-JUN-95. [Details]
(1995)6th ISDE World Congress,
O'Sullivan, G.; Shanahan, F.; O'Mahony, A.; Collins, D.; Collins, J. K.; (1995) *. [N/A], 6th ISDE World Congress, Local Immune Suppression As a Growth and Metastatic Advantage for Human Oesophageal Squamous Cancers , 01-JAN-95 - 30-DEC-99. [Details]

Languages

 LanguageReadingWritingSpeaking
English FluentFluentFluent

Journal Activities

 JournalRoleTo / From
American Journal Of Clinical Nutrition Editor01-OCT-10 -
Gut Member of Editorial Board01-JAN-02 - 31-DEC-05
American Journal Of Gastroenterology Member of Editorial Board01-JAN-97 - 31-DEC-06

Teaching Interests

I place emphasis on learning over teaching and endeavour to make up for the inadequacies of this university by creating an environment conducive to the promotion of learning, research and innovation and to the stimulation of critical thinking by our students rather than traditional rote teaching.                       

Current Postgraduate Students

 StudentDegree TypePrimary
O Brien Morgan Anthony Doctoral DegreeNo
Kennedy Barry Doctoral DegreeYes
Moran Carthage Patrick Doctoral DegreeYes
Cronin Owen Corneilius Doctoral DegreeNo
Clooney Adam George Doctoral DegreeNo