Research Profile

Liam Fanning

Biography

Research Interests

Currently our research is focused on three virus Hepatitis C, Human Immunodeficiency Virus, Hepatitis B and Human Papilloma virus. Together these viruses infect more than 500 million persons. The activation of the host immune system following host penetration and invasion by a virus initiates a conflict that results in either viral clearance or viral persistence. The correlates associated with viral clearance or persistence are not fully determined. Our research in Cork is aimed at advancing our understanding of the molecular diversity of these viruses and how this impacts on disease outcome. Quasispecies diversity is undoubtly responsible, in part, for the failure of isolate specific vaccines for RNA viruses such as HCV and HIV. Our investigation of humoural escape and cytotoxic T cell escape through the molecular signatures present in viral genomes has provides insights in to the breadth of genomic plasticity. Our research has highlighted the likely fitness costs to the virus as evidence by nucleotide reversion in the absence of selection and has provided some insights into correlates necessary for possible development of a vaccine(s) for HCV. Research in to the temporal mapping of quasispecies diversity has for first time demonstrated that even in chronically infected individuals that there is ongoing evolution of envelope glycoproteins, that there is continuous change of potential antigenic epitopes in response to immune selection. We have shown that humoral immune mediated selection of variants can drive movement of the genome sequence spectrum within a quasispecies swarm. Our research with Dr. Mary Horgan, Consultant Infectious Disease, Cork University Hospital has established the breadth of hepatitis B virus and Human Papilloma virus genotype diversity in Ireland. In particular the research into the prevalence of the varying human papilloma genotypes has provided insights into likely vaccine efficacy in women less than 35 years of age.

Exploration of the paediatric virome offers the potential for identifying putative aetiological agents that contribute to illness in children. In conjunction with Dr. Deirdre Murray, Department of Paediatrics, UCC we are using sequence independent technologies to identify known and potentially new viruses present in infants in health and disease states.



Publications

Peer Reviewed Journals

 YearPublication
(2014)'Analysis of the evolution and structure of a complex intrahost viral population in chronic hepatitis C virus mapped by ultradeep pyrosequencing'
Palmer BA, Dimitrova Z, Skums P, Crosbie O, Kenny-Walsh E, Fanning LJ (2014) 'Analysis of the evolution and structure of a complex intrahost viral population in chronic hepatitis C virus mapped by ultradeep pyrosequencing'. Journal of virology, 88 (23):13709-13721 [DOI] [Details]
(2014)'Additive effects of HLA alleles and innate immune genes determine viral outcome in HCV infection'
Karen Fitzmaurice,1 Jacob Hurst,1,2 Megan Dring,3 Andri Rauch,4 Paul J McLaren,5 Huldrych F Günthard,6 Clair Gardiner,3 Paul Klenerman,1,7 Irish HCV Research Consortium and the Swiss HIV Cohort Study (2014) 'Additive effects of HLA alleles and innate immune genes determine viral outcome in HCV infection'. Gut, 0 (0):1-7   [DOI] [Details]
(2014)'p38d MAPK phenotype: an indicator of chemotherapeutic response in oesophageal squamous cell carcinoma'
O'Callaghan C, Fanning LJ, Barry OP (2014) 'p38d MAPK phenotype: an indicator of chemotherapeutic response in oesophageal squamous cell carcinoma'. Anti-cancer drugs, [DOI] [Details]
(2014)'p38�� MAPK: Emerging Roles of a Neglected Isoform. International Journal of Cell Biology'
O' Callaghan C, Fanning LJ, Barry OP (2014) 'p38�� MAPK: Emerging Roles of a Neglected Isoform. International Journal of Cell Biology'. International Journal of Cell Biology, [Details]
(2014)'p38δ MAPK phenotype: an indicator of chemotherapeutic response in oesophageal squamous cell carcinoma'
O' Callaghan C, Fanning LJ, Barry OP (2014) 'p38δ MAPK phenotype: an indicator of chemotherapeutic response in oesophageal squamous cell carcinoma'. Anti Cancer Drugs, [Details]
(2013)'Targeting P38 delta MAPK in Oesophageal Cancer: a Possible Future Therapeutic Goal?'
O'Callaghan, C,Fanning, L,Houston, A,Barry, OP (2013) 'Targeting P38 delta MAPK in Oesophageal Cancer: a Possible Future Therapeutic Goal?'. International Journal of Oncology, [Details]
(2013)'Clinical Relevance of Detectable Hepatitis C Virus RNA in the Context of Direct-Acting Antivirals'
O'Sullivan, K,Levis, J,Hegarty, K,Crosbie, O,Kenny-Walsh, E,Fanning, LJ (2013) 'Clinical Relevance of Detectable Hepatitis C Virus RNA in the Context of Direct-Acting Antivirals'. Hepatology, 57 :855-856 [DOI] [Details]
(2013)'Loss of p38δ mitogen-activated protein kinase expression promotes oesophageal squamous cell carcinoma proliferation, migration and anchorage-independent growth'
O'Callagahan C, Fanning LJ, Houston A and Barry OP. (2013) 'Loss of p38δ mitogen-activated protein kinase expression promotes oesophageal squamous cell carcinoma proliferation, migration and anchorage-independent growth'. International Journal of Oncology, [Details]
(2013)'Hepatitis C Virus targets the Interferon-α JAK/STAT pathway by promoting proteosomal degradation in immune cells and hepatocytes'
Nigel J. Stevenson,1,*,+ Nollaig M. Bourke,1,+ Elizabeth J. Ryan,1 Marco Binder,2 Liam Fanning,3 James A. Johnston,4 John E. Hegarty,5 Aideen Long,6,7 and Cliona O’Farrelly1,7. (2013) 'Hepatitis C Virus targets the Interferon-α JAK/STAT pathway by promoting proteosomal degradation in immune cells and hepatocytes'. Febs Letters, [Details]
(2013)'Clinical relevance of detectable hepatitis C virus RNA in the context of direct-acting antivirals'
Kathleen O'sullivan, John Levis, Kevin Hegarty, Orla Crosbie, Elizabeth Kenny-Walsh, Liam J. Fanning. (2013) 'Clinical relevance of detectable hepatitis C virus RNA in the context of direct-acting antivirals'. Hepatology, 57 (2) [DOI] [Details]
(2013)'Hepatitis C virus targets the interferon-alpha JAK/STAT pathway by promoting proteasomal degradation in immune cells and hepatocytes'
Stevenson, NJ,Bourke, NM,Ryan, EJ,Binder, M,Fanning, L,Johnston, JA,Hegarty, JE,Long, A,O'Farrelly, C (2013) 'Hepatitis C virus targets the interferon-alpha JAK/STAT pathway by promoting proteasomal degradation in immune cells and hepatocytes'. Febs Letters, 587 :1571-1578 [DOI] [Details]
(2013)'New paradigms for the modulatory actions of p38 MAPK restorative expression in esophageal squamous cancer cell growth, migration and response to chemotherapy: A possible future therapeutic target?'
O’Callaghan G, Fanning L, Houston A and Barry OP. (2013) 'New paradigms for the modulatory actions of p38 MAPK restorative expression in esophageal squamous cancer cell growth, migration and response to chemotherapy: A possible future therapeutic target?'. [Details]
(2013)'Loss of p38 delta mitogen-activated protein kinase expression promotes oesophageal squamous cell carcinoma proliferation, migration and anchorage-independent growth'
O'Callaghan, C,Fanning, LJ,Houston, A,Barry, OP (2013) 'Loss of p38 delta mitogen-activated protein kinase expression promotes oesophageal squamous cell carcinoma proliferation, migration and anchorage-independent growth'. International Journal of Oncology, 43 :405-415 [DOI] [Details]
(2012)'Insertion and recombination events at hypervariable region 1 over 9.6 years of hepatitis C virus chronic infection'
Palmer BA, Moreau I, Levis J, Harty C, Crosbie O, Kenny-Walsh E, Fanning LJ (2012) 'Insertion and recombination events at hypervariable region 1 over 9.6 years of hepatitis C virus chronic infection'. The Journal of General Virology, 93 (Pt 12):2614-2624 [DOI] [Details]
(2012)'Hepatitis C quasispecies adaptation in the setting of a variable fidelity polymerase'
Schmidt-Martin D, Crosbie O, Kenny-Walsh E, Fanning LJ (2012) 'Hepatitis C quasispecies adaptation in the setting of a variable fidelity polymerase'. Journal of Virus Adaptation and Treatment, 4 (1):43-50 [DOI] [CORA Link] [Details]
(2012)'The prevalence and genotype of human papillomavirus on cervical samples from an Irish female population with external genital warts'
Cremin, S,Menton, JF,Canier, L,Horgan, M,Fanning, LJ (2012) 'The prevalence and genotype of human papillomavirus on cervical samples from an Irish female population with external genital warts'. Human Vaccines & Immunotherapeutics, 8 :916-920 [DOI] [Details]
(2012)'The pan-genotype specificity of the hepatitis C virus anti-core monoclonal antibody C7-50 is contingent on the quasispecies profile of a population'
Palmer, BA,Menton, J,Levis, J,Kenny-Walsh, E,Crosbie, O,Fanning, LJ (2012) 'The pan-genotype specificity of the hepatitis C virus anti-core monoclonal antibody C7-50 is contingent on the quasispecies profile of a population'. Archives of Virology, 157 :2235-2239 [DOI] [Details]
(2012)'Constraints on Viral Evolution during Chronic Hepatitis C Virus Infection Arising from a Common-Source Exposure'
Bailey, JR,Laskey, S,Wasilewski, LN,Munshaw, S,Fanning, LJ,Kenny-Walsh, E,Ray, SC (2012) 'Constraints on Viral Evolution during Chronic Hepatitis C Virus Infection Arising from a Common-Source Exposure'. Journal of Virology, 86 :12582-12590 [DOI] [Details]
(2012)'Insertion and recombination events at hypervariable region 1 over 9.6 years of hepatitis C virus chronic infection'
Palmer, BA,Moreau, I,Levis, J,Harty, C,Crosbie, O,Kenny-Walsh, E,Fanning, LJ (2012) 'Insertion and recombination events at hypervariable region 1 over 9.6 years of hepatitis C virus chronic infection'. The Journal of General Virology, 93 :2614-2624 [DOI] [Details]
(2011)'Retroviruses: Molecular Biology, Genomics and Pathogenesis'
Liam J. Fanning; (2011) 'Retroviruses: Molecular Biology, Genomics and Pathogenesis'. Clinical Infectious Diseases, 52 (2) [DOI] [Details]
(2010)'World Health Organization collaborative study to calibrate the 3rd International Standard for Hepatitis C virus RNA nucleic acid amplification technology (NAT)-based assays'
S. A. Baylis1, A. B. Heath2, the Collaborative Study Group† (2010) 'World Health Organization collaborative study to calibrate the 3rd International Standard for Hepatitis C virus RNA nucleic acid amplification technology (NAT)-based assays'. Vox Sanguinis, 100 (4):409-417   [DOI] [Details]
(2009)'Molecular epidemiology of sexually transmitted human papillomavirus in a self referred group of women in Ireland'
Menton JF, Cremin SM, Canier L, Horgan M, Fanning LJ (2009) 'Molecular epidemiology of sexually transmitted human papillomavirus in a self referred group of women in Ireland'. Virology Journal, 23 (6)   [DOI] [Details]
(2009)'Histological Changes in Hepatitis C Virus Antibody-Positive, Hepatitis C Virus RNA-Negative Subjects Suggest Persistent Virus Infection'
Moreau, Isabelle and Kenny-Walsh, Elizabeth and Crosbie, Orla and Fanning, Liam J.; (2009) 'Histological Changes in Hepatitis C Virus Antibody-Positive, Hepatitis C Virus RNA-Negative Subjects Suggest Persistent Virus Infection'. Hepatology, 49 (4) [DOI] [Details]
(2009)'Molecular epidemiology of sexually transmitted human papillomavirus in a self referred group of women in Ireland'
Menton, JF,Cremin, SM,Canier, L,Horgan, M,Fanning, LJ; (2009) 'Molecular epidemiology of sexually transmitted human papillomavirus in a self referred group of women in Ireland'. Virology Journal, 6 [DOI] [Details]
(2009)'Quasispecies: Future proofing RNA viruses'
Fanning, Liam J.; (2009) 'Quasispecies: Future proofing RNA viruses'. International Journal of Molecular Medicine, 24 (Suppl. 1) [Details]
(2008)'Separation of Hepatitis C genotype 4a into IgG-depleted and IgG-enriched fractions reveals a unique quasispecies profile'
Moreau, I,O'Sullivan, H,Murray, C,Levis, J,Crosbie, O,Kenny-Walsh, E,Fanning, LJ (2008) 'Separation of Hepatitis C genotype 4a into IgG-depleted and IgG-enriched fractions reveals a unique quasispecies profile'. Virology Journal, 5 [DOI] [CORA Link] [Details]
(2008)'Retrospective analysis of chronic hepatitis C in untreated patients with nonlinear mixed effects model'
Jian Huang, Kathleen O’Sullivan, John Levis, Elizabeth Kenny-Walsh, Orla Crosbie, Liam Fanning (2008) 'Retrospective analysis of chronic hepatitis C in untreated patients with nonlinear mixed effects model'. J. Biomedical Science and Engineering, (1):85-90 [DOI] [Details]
(2008)'Correlation between pre-treatment quasispecies complexity and treatment outcome in chronic HCV genotype 3a'
Moreau, I,Levis, J,Crosbie, O,Kenny-Walsh, E,Fanning, LJ (2008) 'Correlation between pre-treatment quasispecies complexity and treatment outcome in chronic HCV genotype 3a'. Virology Journal, 5 [DOI] [Details]
(2008)'Practical consequences of hepatitis C virus quasispecies for target-specific antivirals'
Fanning, LJ; (2008) 'Practical consequences of hepatitis C virus quasispecies for target-specific antivirals'. Journal of Infectious Diseases, 198 :797-799 [DOI] [Details]
(2008)'Molecular Epidemiology and Interferon Susceptibility of the Natural Recombinant Hepatitis C Virus Strain RF1\_2k/1b'
Kurbanov, Fuat and Tanaka, Yasuhito and Chub, Elena and Maruyama, Isao and Azlarova, Aziza and Kamitsukasa, Hiroshi and Ohno, Tomoyoshi and Bonetto, Stefania and Moreau, Isabelle and Fanning, Liam J. and Legrand-Abravanel, Florence and Izopet, Jaques and Naoumov, Nikolai and Shimada, Takashi and Netesov, Sergei and Mizokami, Masashi; (2008) 'Molecular Epidemiology and Interferon Susceptibility of the Natural Recombinant Hepatitis C Virus Strain RF1\_2k/1b'. JOURNAL OF INFECTIOUS DISEASES, 198 (10):1448-1456 [DOI] [Details]
(2007)'In vitro replication models for the hepatitis C virus'
Sheehy, P. and Mullan, B. and Moreau, I. and Kenny-Walsh, E. and Shanahan, F. and Scallan, M. and Fanning, L. J.; (2007) 'In vitro replication models for the hepatitis C virus'. JOURNAL OF VIRAL HEPATITIS, 14 (1):2-10 [DOI] [Details]
(2007)'Baseline genotypic resistance testing in untreated hepatitis B virus infection'
Feeney, Foin and Fanning, Liam J. and Horgan, Mary; (2007) 'Baseline genotypic resistance testing in untreated hepatitis B virus infection'. GASTROENTEROLOGY, 132 (4, Suppl. 2) [Details]
(2007)'In vitro replication models for the hepatitis C virus'
Sheehy, P.,Mullan, B.,Moreau, I.,Kenny-Walsh, E.,Shanahan, F.,Scallan, M.,Fanning, L. J. (2007) 'In vitro replication models for the hepatitis C virus'. J Viral Hepat, 14 (11):2-102   [Details]
(2006)'Hepatitis B genotype and YMDD profiles in an untreated Irish population'
Horgan M, Brannigan E, Crowley B, Levis J, Fanning LJ (2006) 'Hepatitis B genotype and YMDD profiles in an untreated Irish population'. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 35 (2):203-204 [DOI] [Details]
(2006)'Serendipitous identification of natural Intergenotypic recombinants of hepatitis C in Ireland'
Moreau, I,Hegarty, S,Levis, J,Sheehy, P,Crosbie, O,Kenny-Walsh, E,Fanning, LJ (2006) 'Serendipitous identification of natural Intergenotypic recombinants of hepatitis C in Ireland'. Virology Journal, 3 [DOI] [CORA Link] [Details]
(2005)'Viral load change and sequential evolution of entire hepatitis C virus genome in Irish recipients of single source-contaminated anti-D immunoglobulin*'
Itakura J, Nagayama K, Enomoto N, Hamano K, Sakamoto N, Fanning LJ, Kenny-Walsh E, Shanahan F, Watanabe M.; (2005) 'Viral load change and sequential evolution of entire hepatitis C virus genome in Irish recipients of single source-contaminated anti-D immunoglobulin*'. Journal of Viral Hepatitis, 12 (6):594-603 [Details]
(2005)'A strategy for obtaining near full-length HCV clones (assemblicons) by assembly PCR'
Sheehy,P., Scallan,M., Kenny-Walsh,E., Shanahan,F., Fanning,L.J.; (2005) 'A strategy for obtaining near full-length HCV clones (assemblicons) by assembly PCR'. Journal of Virological Methods, 123 (2):115-124 [Details]
(2005)'Anti-viral therapies for hepatitis C virus infection: Current options and evolving candidate drugs'
Fanning, LJ; (2005) 'Anti-viral therapies for hepatitis C virus infection: Current options and evolving candidate drugs'. LETTERS IN DRUG DESIGN \& DISCOVERY, 2 (2):150-161 [Details]
(2005)'Divergent and convergent evolution after a common-source outbreak of hepatitis C virus'
Ray SC, Fanning L, Wang XH, Netski DM, Kenny-Walsh E, Thomas DL (2005) 'Divergent and convergent evolution after a common-source outbreak of hepatitis C virus'. The Journal of Experimental Medicine, 201 (11):1753-1759 [DOI] [CORA Link] [Details]
(2005)'Viral load change and sequential evolution of entire hepatitis C virus genome in Irish recipients of single source-contaminated anti-D immunoglobulin'
Itakura, J.,Nagayama, K.,Enomoto, N.,Hamano, K.,Sakamoto, N.,Fanning, L. J.,Kenny-Walsh, E.,Shanahan, F.,Watanabe, M. (2005) 'Viral load change and sequential evolution of entire hepatitis C virus genome in Irish recipients of single source-contaminated anti-D immunoglobulin'. J Viral Hepat, 12 (66):594-603594   [Details]
(2005)'Divergent and convergent evolution after a common-source outbreak of hepatitis C virus'
Ray, SC,Fanning, L,Wang, XH,Netski, DM,Walsh-Kenny, E,Thomas, DL (2005) 'Divergent and convergent evolution after a common-source outbreak of hepatitis C virus'. The Journal of Experimental Medicine, 201 :1753-1759 [DOI] [Details]
(2004)'Do Taq-generated RT-PCR products from RNA viruses accurately reflect viral genetic heterogeneity?'
Mullan B, Sheehy P, Shanahan F, Fanning L.; (2004) 'Do Taq-generated RT-PCR products from RNA viruses accurately reflect viral genetic heterogeneity?'. Journal of Viral Hepatitis, 11 (2):108-114 [Details]
(2004)'Persistence of hepatitis C virus in a white population: associations with human leukocyte antigen class 1'
Fanning, L. J.,Kenny-Walsh, E.,Shanahan, F. (2004) 'Persistence of hepatitis C virus in a white population: associations with human leukocyte antigen class 1'. Hum Immunol, 65 (77):745-51 [Details]
(2004)'Persistence of hepatitis C virus in a white population: Associations with human leukocyte antigen class 1'
Fanning, L. J. and Kenny-Walsh, E. and Shanahan, F. (2004) 'Persistence of hepatitis C virus in a white population: Associations with human leukocyte antigen class 1'. Human Immunology, 65 (7):745-751 [Details]
(2002)'RT-PCR for the assessment of genetically heterogenous populations of the hepatitis C virus'
Mullan, B.,Fanning, L. J.,Shanahan, F.,Sullivan, D. G. (2002) 'RT-PCR for the assessment of genetically heterogenous populations of the hepatitis C virus'. Methods Mol Biol, 193 :171-88 [Details]
(2002)'The Irish paradigm on the natural progression of hepatitis C virus infection: An investigation in a homogeneous patient population infected with HCV 1b (Review)'
Fanning, LJ; (2002) 'The Irish paradigm on the natural progression of hepatitis C virus infection: An investigation in a homogeneous patient population infected with HCV 1b (Review)'. International Journal of Molecular Medicine, 9 :179-184 [Details]
(2001)'Inferred hepatitis C virus quasispecies diversity is influenced by choice of DNA polymerase in reverse transcriptase-polymerase chain reactions'
Mullan, B.,Kenny-Walsh, E.,Collins, J. K.,Shanahan, F.,Fanning, L. J. (2001) 'Inferred hepatitis C virus quasispecies diversity is influenced by choice of DNA polymerase in reverse transcriptase-polymerase chain reactions'. Anal Biochem, 289 (22):137-146137   [Details]
(2001)'Tissue viral load variability in chronic hepatitis C'
Fanning, L,Loane, J,Kenny-Walsh, E,Sheehan, M,Whelton, M,Kirwan, W,Collins, JK,Shanahan, F; (2001) 'Tissue viral load variability in chronic hepatitis C'. American Journal of Gastroenterology, 96 :3384-3389   [Details]
(2001)'Inferred hepatitis C virus quasispecies diversity is influenced by choice of DNA polymerase in reverse transcriptase-polymerase chain reactions'
Mullan, B,Kenny-Walsh, E,Collins, JK,Shanahan, F,Fanning, LJ (2001) 'Inferred hepatitis C virus quasispecies diversity is influenced by choice of DNA polymerase in reverse transcriptase-polymerase chain reactions'. Analytical Biochemistry, 289 :137-146 [DOI] [Details]
(2001)'Purification and some characteristics of a recombinant dimeric rhizobium meliloti beta-galactosidase expressed in escherichia coli'
Leahy M, Vaughan P, Fanning L, Fanning S, Sheehan D; (2001) 'Purification and some characteristics of a recombinant dimeric rhizobium meliloti beta-galactosidase expressed in escherichia coli'. Enzyme and Microbial Technology, 28 (7-8):682-688 [Details]
(2001)'Strategy for the maximization of clinically relevant information from hepatitis C virus, RT-PCR quantification'
Levis, J,Kenny-Walsh, E,O'Sullivan, K,Horgan, M,Whelton, M,Shanahan, F,Fanning, L; (2001) 'Strategy for the maximization of clinically relevant information from hepatitis C virus, RT-PCR quantification'. Rna-A Publication of The Rna Society, 20 :163-171   [Details]
(2001)'HLA class II genes determine the natural variance of hepatitis C viral load'
Fanning, L. J. and Levis, J. and Kenny-Walsh, E. and Whelton, M. and O'Sullivan, K. and Shanahan, F. (2001) 'HLA class II genes determine the natural variance of hepatitis C viral load'. Hepatology, 33 (1):224-230 [Details]
(2000)'Natural fluctuations of hepatitis C viral load in a homogeneous patient population: A prospective study'
Fanning, L,Kenny-Walsh, E,Levis, J,Choudhury, KR,Cannon, B,Sheehan, M,Whelton, M,Shanahan, F; (2000) 'Natural fluctuations of hepatitis C viral load in a homogeneous patient population: A prospective study'. Hepatology, 31 :225-229 [Details]
(2000)'Pregnancy and pregnancy outcome in hepatitis C type 1b'
Jabeen, T.,Cannon, B.,Hogan, J.,Crowley, M.,Devereux, C.,Fanning, L.,Kenny-Walsh, E.,Shanahan, F.,Whelton, M. J. (2000) 'Pregnancy and pregnancy outcome in hepatitis C type 1b'. Qjm-an International Journal of Medicine, 93 (99):597-601597   [Details]
(2000)'Natural fluctuations of hepatitis C viral load in a homogeneous patient population: A prospective study'
Fanning, L. and Kenny-Walsh, E. and Levis, J. and Choudhury, K. R. and Cannon, B. and Sheehan, M. and Whelton, M. and Shanahan, F. (2000) 'Natural fluctuations of hepatitis C viral load in a homogeneous patient population: A prospective study'. Hepatology, 31 (1):225-229 [Details]
(2000)'Pregnancy and pregnancy outcome in hepatitis C type 1b'
Jabeen, T,Cannon, B,Hogan, J,Crowley, M,Devereux, C,Fanning, L,Kenny-Walsh, E,Shanahan, F,Whelton, MJ; (2000) 'Pregnancy and pregnancy outcome in hepatitis C type 1b'. QJM: Monthly Journal of The Association of Physicians, 93 :597-601   [Details]
(2000)'Viral clearance in hepatitis C (1b) infection: Relationship with human leukocyte antigen class II in a homogeneous population'
Fanning, L. J. and Levis, J. and Kenny-Walsh, E. and Wynne, F. and Whelton, M. and Shanahan, F. (2000) 'Viral clearance in hepatitis C (1b) infection: Relationship with human leukocyte antigen class II in a homogeneous population'. Hepatology, 31 (6):1334-1337 [Details]
(2000)'The hepatitis C virus: master of diversity and challenging adversity'
Fanning LJ and Shanahan F (2000) 'The hepatitis C virus: master of diversity and challenging adversity'. Medscape Journal of Medicine,   [Details]
(2000)'Viral clearance in hepatitis C (1b) infection: relationship with human leukocyte antigen class II in a homogeneous population'
Fanning, L. J.,Levis, J.,Kenny-Walsh, E.,Wynne, F.,Whelton, M.,Shanahan, F. (2000) 'Viral clearance in hepatitis C (1b) infection: relationship with human leukocyte antigen class II in a homogeneous population'. Hepatology, 31 (66):1334-7 [Details]
(2000)'Natural fluctuations of hepatitis C viral load in a homogeneous patient population: a prospective study'
Fanning, L.,Kenny-Walsh, E.,Levis, J.,Choudhury, K. R.,Cannon, B.,Sheehan, M.,Whelton, M.,Shanahan, F. (2000) 'Natural fluctuations of hepatitis C viral load in a homogeneous patient population: a prospective study'. Hepatology, 31 (11):225-9225   [Details]
(1999)'Detection of anti-interferon antibodies during in terferon-alpha anti-viral therapy in individuals with chronic hepatitis'
Fanning, LJ and Levis, J and Kenny-Walsh, E and Shanahan, FLJ; (1999) 'Detection of anti-interferon antibodies during in terferon-alpha anti-viral therapy in individuals with chronic hepatitis'. GASTROENTEROLOGY, 116 (4, Part 2) [Details]
(1999)'Hepatitis C virus HVR and ISDR quasispecies diversities are profoundly influenced by choice of DNA polymerase'
Mullan, B. M.,Kenny-Walsh, E.,Collins, J. K.,Shanahan, F. L.,Fanning, L. J. (1999) 'Hepatitis C virus HVR and ISDR quasispecies diversities are profoundly influenced by choice of DNA polymerase'. Hepatology, 30 (44)   [Details]
(1999)'Detection of anti-interferon antibodies during in terferon-alpha anti-viral therapy in individuals with chronic hepatitis'
Fanning, L. J.,Levis, J.,Kenny-Walsh, E.,Shanahan, F. L. J. (1999) 'Detection of anti-interferon antibodies during in terferon-alpha anti-viral therapy in individuals with chronic hepatitis'. Gastroenterology, 116 (44)   [Details]
(1999)'Natural fluctuations in viral load in hepatitis C infection in a homogeneous patient population: A prospective study'
Fanning, L. J.,Kenny-Walsh, E.,Levis, S. J.,Sheehan, M.,Cannon, B.,Whelton, M. J.,Shanahan, F. L. (1999) 'Natural fluctuations in viral load in hepatitis C infection in a homogeneous patient population: A prospective study'. Hepatology, 30 (44)   [Details]
(1999)'Viral load and clinicopathological features of chronic hepatitis C (1b) in a homogeneous patient population'
Fanning, L,Kenny, E,Sheehan, M,Cannon, B,Whelton, M,O'Connell, J,Collins, JK,Shanahan, F; (1999) 'Viral load and clinicopathological features of chronic hepatitis C (1b) in a homogeneous patient population'. Hepatology, 29 :904-907 [DOI] [Details]
(1999)'Hepatitis C virus HVR and ISDR quasispecies diversities are profoundly influenced by choice of DNA polymerase'
Mullan, BM and Kenny-Walsh, E and Collins, JK and Shanahan, FL and Fanning, LJ; (1999) 'Hepatitis C virus HVR and ISDR quasispecies diversities are profoundly influenced by choice of DNA polymerase'. HEPATOLOGY, 30 (4, Part 2 Suppl. S) [Details]
(1999)'Hepatic biopsy sampling variability in chronic hepatitis C'
Fanning, L. J.,Loane, J.,Kenny-Walsh, E.,Sheehan, M.,Crowley, M.,Whelton, M. J.,Kirwan, W. O.,Collins, J. K.,Shanahan, F. L. (1999) 'Hepatic biopsy sampling variability in chronic hepatitis C'. Gastroenterology, 116 (44)   [Details]
(1999)'Hepatic biopsy sampling variability in chronic hepatitis C'
Fanning, L. J.,Loane, J.,Kenny-Walsh, E.,Sheehan, M.,Crowley, M. J.,Whelton, M. J.,Kirwan, W. O.,Shanahan, F. L. (1999) 'Hepatic biopsy sampling variability in chronic hepatitis C'. Hepatology, 30 (44)   [Details]
(1999)'Hepatic biopsy sampling variability in chronic hepatitis C'
Fanning, LJ and Loane, J and Kenny-Walsh, E and Sheehan, M and Crowley, MJ and Whelton, MJ and Kirwan, WO and Shanahan, FL; (1999) 'Hepatic biopsy sampling variability in chronic hepatitis C'. HEPATOLOGY, 30 (4, Part 2 Suppl. S) [Details]
(1998)'Molecular mechanisms involved in receptor editing at the Ig heavy chain locus'
Fanning L, Bertrand FE, Steinberg C, Wu GE. (1998) 'Molecular mechanisms involved in receptor editing at the Ig heavy chain locus'. International immunology, 10 (2):241-246 [Details]
(1998)'Serum viral load and clincopathologic progression of hepatitis C (1b): A study in a homogenous patient population'
Fanning, L.,Kenny, E.,Collins, J. K.,Sheehan, M.,Shanahan, F. (1998) 'Serum viral load and clincopathologic progression of hepatitis C (1b): A study in a homogenous patient population'. Gastroenterology, 114 (44)   [Details]
(1998)'Hepatitis C viral load variability in hepatitis C virus infected patients'
Fanning, L and Loane, J and Kenny-Walsh, E and Sheehan, M and Whelton, M and Kirwan, WO and Collins, JK and Shanahan, F; (1998) 'Hepatitis C viral load variability in hepatitis C virus infected patients'. HEPATOLOGY, 28 (4, Part 2 Suppl. S) [Details]
(1998)'Viral persistence or clearance in Hepatitis C (1b) infection: Relationship with HLA class II type'
Fanning, L and Levis, J and Kenny-Walsh, E and Collins, JK and Shanahan, F; (1998) 'Viral persistence or clearance in Hepatitis C (1b) infection: Relationship with HLA class II type'. HEPATOLOGY, 28 (4, Part 2 Suppl. S) [Details]
(1998)'Minimal progression of hepatitis C type 1b in non immune compromised Irish women'
Cannon, BG and Loane, J and Corbett, S and Fanning, L and Kenny, E and Buckley, J and McFeely, L and Hogan, J and Devereux, C and Crowley, MJ and Whelton, MJ and Shanahan, F; (1998) 'Minimal progression of hepatitis C type 1b in non immune compromised Irish women'. HEPATOLOGY, 28 (4, Part 2 Suppl. S) [Details]
(1998)'Serum viral load and clincopathologic progression of hepatitis C (1b): A study in a homogenous patient population'
Fanning, L and Kenny, E and Collins, JK and Sheehan, M and Shanahan, F; (1998) 'Serum viral load and clincopathologic progression of hepatitis C (1b): A study in a homogenous patient population'. GASTROENTEROLOGY, 114 (4, Part 2 Suppl. S) [Details]
(1998)'Sensitivity of PCR-based assays for hepatitis c virus can be influenced by choice of DNA polymerase'
Mullan, BM and Kenny-Walsh, E and Collins, JK and Shanahan, F and Fanning, LJ; (1998) 'Sensitivity of PCR-based assays for hepatitis c virus can be influenced by choice of DNA polymerase'. HEPATOLOGY, 28 (4, Part 2 Suppl. S) [Details]
(1998)'Minimal progression of hepatitis C type 1b in non immune compromised Irish women'
Cannon, B. G.,Loane, J.,Corbett, S.,Fanning, L.,Kenny, E.,Buckley, J.,McFeely, L.,Hogan, J.,Devereux, C.,Crowley, M. J.,Whelton, M. J.,Shanahan, F. (1998) 'Minimal progression of hepatitis C type 1b in non immune compromised Irish women'. Hepatology, 28 (44)   [Details]
(1998)'Hepatitis C viral load variability in hepatitis C virus infected patients'
Fanning, L.,Loane, J.,Kenny-Walsh, E.,Sheehan, M.,Whelton, M.,Kirwan, W. O.,Collins, J. K.,Shanahan, F. (1998) 'Hepatitis C viral load variability in hepatitis C virus infected patients'. Hepatology, 28 (44)   [Details]
(1998)'Viral persistence or clearance in Hepatitis C (1b) infection: Relationship with HLA class II type'
Fanning, L.,Levis, J.,Kenny-Walsh, E.,Collins, J. K.,Shanahan, F. (1998) 'Viral persistence or clearance in Hepatitis C (1b) infection: Relationship with HLA class II type'. Hepatology, 28 (44)   [Details]
(1998)'Sensitivity of PCR-based assays for hepatitis c virus can be influenced by choice of DNA polymerase'
Mullan, B. M.,Kenny-Walsh, E.,Collins, J. K.,Shanahan, F.,Fanning, L. J. (1998) 'Sensitivity of PCR-based assays for hepatitis c virus can be influenced by choice of DNA polymerase'. Hepatology, 28 (44)   [Details]
(1997)'The relationship of serum quantitative PCR, aminotransferases and liver histology in monitoring the progression of chronic hepatitis C'
Fanning, L and Kenny, E and Cannon, B and Crowley, M and Shanahan, F; (1997) 'The relationship of serum quantitative PCR, aminotransferases and liver histology in monitoring the progression of chronic hepatitis C'. HEPATOLOGY, 26 (4, Part 2 Suppl. S) [Details]
(1996)'Development of the immunoglobulin repertoire'
Fanning, LJ and Connor, AM and Wu, GE; (1996) 'Development of the immunoglobulin repertoire'. CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY, 79 (1):1-14 [Details]
(1996)'Mouse RSS spacer sequences affect the rate of V(D)J recombination'
Fanning L, Connor A, Baetz K, Ramsden D, Wu GE. (1996) 'Mouse RSS spacer sequences affect the rate of V(D)J recombination'. Immunogenetics, 44 (2):146-150 [Details]
(1995)'MOUSE V(H)7183 RECOMBINATION SIGNAL SEQUENCES MEDIATE RECOMBINATION MORE FREQUENTLY THAN THOSE OF VHJ558'
CONNOR, AM and FANNING, LJ and CELLER, JW and HICKS, LK and RAMSDEN, DA and WU, GE; (1995) 'MOUSE V(H)7183 RECOMBINATION SIGNAL SEQUENCES MEDIATE RECOMBINATION MORE FREQUENTLY THAN THOSE OF VHJ558'. JOURNAL OF IMMUNOLOGY, 155 (11):5268-5272 [Details]
(1994)'The Eurogem Map of Human Chromosome 15 [B3096]'
Joyce, C.; Fanning, L.; Malcolm, S.; Richard, L.; Broux, O.; Beckman, J. S.; Flint, T.; Kruse, T. A.; Vergnaud, G.; Cox, S. A.; Sandro, O.; Contu, L.; McCarthy, T. V.; (1994) 'The Eurogem Map of Human Chromosome 15 [B3096]'. European Journal of Human Genetics, 2 :232-233 [Details]
(1993)'A shuttle vector system for the rapid detection of recombination in murine cells'
Fanning LJ, McCarthy TV; (1993) 'A shuttle vector system for the rapid detection of recombination in murine cells'. Nucleic Acids Research, 21 (23):5530-5531 [Details]
(1990)'Class-switch recombination in extrachromosomal DNA substrates in murine pre-B-cells'
Fanning LJ, O'Regan E, McCarthy S, McCarthy TV; (1990) 'Class-switch recombination in extrachromosomal DNA substrates in murine pre-B-cells'. Biochemical Society Transactions, 18 (2):356-357 [Details]

Conference Publications

 YearPublication
(2014)6th International Conference on Education and New Learning Technologies
John O’Mullane and Kathleen O’Sullivan and David O’Sullivan and Liam Fanning (2014) A FEEDBACK SYSTEM TO SUPPORT SELF-REGULATED LEARNING . In: INTED eds. 6th International Conference on Education and New Learning Technologies Barcelona, Spain, , 06-JUL-14 - 09-JUL-14 , pp.3500-3509 [Details]
(2008)2nd International Conference on Bioinformatics and Biomedical Engineering (iCBBE)
Huang J., O'Sullivan, K., Kenny-Wlash, E., Crosbie, O., Lewis, J., Fanning, L.J. (2008) Nonlinear Mixed Effects Modelling Viral Load in Untreated Patients with Chronic Hepatitis C 2nd International Conference on Bioinformatics and Biomedical Engineering (iCBBE) China, [Details]
(2010)Conference on Applied Statistics in Ireland
Doherty, C., O’Sullivan, K., O’Mullane, J., McCarthy, C., Fanning, L.J. (2010) Identification of Subgroups of Chronic Hepatitis C Individuals Conference on Applied Statistics in Ireland Portrush, Northern Ireland, , 16-MAY-10 - 18-MAY-10 [Details]
(2009)Translational Health Research Conference
Doherty C, McCarthy C, Vargyas E, O’Sullivan K, Levis J, Crosbie O, Kenny-Walsh E, and Fanning LJ (2009) Viral clustering in chronic hepatitis C Translational Health Research Conference University College Cork, Ireland, , 24-JUN-09 - 24-JUN-09 [Details]

Book Chapters

 YearPublication
(2002)'Detection and quantification of the hepatitis C viral genome'
Fanning LJ. (2002) 'Detection and quantification of the hepatitis C viral genome' In: RT-PCR Protocols. London: Humana Press. [DOI] [Details]
(2002)'RT-PCR for the assessment of genetically heterogenous populations of the hepatitis C virus'
Mullan, Brian and Fanning, Liam J. and Shanahan, Fergus and Sullivan, Daniel G. (2002) 'RT-PCR for the assessment of genetically heterogenous populations of the hepatitis C virus' In: Methods In Molecular Biology. London: Humana Press. [DOI] [Details]

Abstract

 YearPublication
(2013)New paradigms for the modulatory actions of p38 delta MAPK restorative expression in esophageal squamous cancer cell growth, migration and response to chemotherapy: A possible future therapeutic target.
O'Callaghan, C,Fanning, L,Houston, A,Barry, OP (2013) New paradigms for the modulatory actions of p38 delta MAPK restorative expression in esophageal squamous cancer cell growth, migration and response to chemotherapy: A possible future therapeutic target. Abstract [DOI] [Details]
(2013)Intensive mapping of HCV quasispecies change provides novel insights into the natural history of chronic infection at a molecular level.
Schmidt-Martin, D,Fanning, LJ,Kenny-Walshe, E,Crosbie, OM (2013) Intensive mapping of HCV quasispecies change provides novel insights into the natural history of chronic infection at a molecular level. Abstract [Details]
(2013)Association of IL-28B polymorphisms with the natural history of Hepatitis C in an Irish cohort.
Moran, C,Corbett, S,Kenny-Walsh, E,Fanning, LJ,Crosbie, OM (2013) Association of IL-28B polymorphisms with the natural history of Hepatitis C in an Irish cohort. Abstract [Details]
(2012)ASSOCIATION BETWEEN A POLYMORPHISM IN THE FRACTALKINE RECEPTOR, CX3CR1, AND RHEUMATOID ARTHRITIS.
Stack, J,Hegarty, K,Murphy, G,O'Sullivan, M,Fanning, L,Healy, L,Daly, M,Harney, S,Shanahan, F,Molloy, M (2012) ASSOCIATION BETWEEN A POLYMORPHISM IN THE FRACTALKINE RECEPTOR, CX3CR1, AND RHEUMATOID ARTHRITIS. Abstract [Details]
(2009)Quasispecies: Future proofing RNA viruses.
Fanning, LJ (2009) Quasispecies: Future proofing RNA viruses. Abstract [Details]
(1999)Hepatitis C virus HVR and ISDR quasispecies diversities are profoundly influenced by choice of DNA polymerase.
Mullan, BM,Kenny-Walsh, E,Collins, JK,Shanahan, FL,Fanning, LJ (1999) Hepatitis C virus HVR and ISDR quasispecies diversities are profoundly influenced by choice of DNA polymerase. Abstract [Details]
(1999)Natural fluctuations in viral load in hepatitis C infection in a homogeneous patient population: A prospective study.
Fanning, LJ,Kenny-Walsh, E,Levis, SJ,Sheehan, M,Cannon, B,Whelton, MJ,Shanahan, FL (1999) Natural fluctuations in viral load in hepatitis C infection in a homogeneous patient population: A prospective study. Abstract [Details]
(1999)Hepatic biopsy sampling variability in chronic hepatitis C.
Fanning, LJ,Loane, J,Kenny-Walsh, E,Sheehan, M,Crowley, M,Whelton, MJ,Kirwan, WO,Collins, JK,Shanahan, FL (1999) Hepatic biopsy sampling variability in chronic hepatitis C. Abstract [Details]
(1999)Detection of anti-interferon antibodies during in terferon-alpha anti-viral therapy in individuals with chronic hepatitis.
Fanning, LJ,Levis, J,Kenny-Walsh, E,Shanahan, FLJ (1999) Detection of anti-interferon antibodies during in terferon-alpha anti-viral therapy in individuals with chronic hepatitis. Abstract [Details]
(1998)Hepatitis C viral load variability in hepatitis C virus infected patients.
Fanning, L,Loane, J,Kenny-Walsh, E,Sheehan, M,Whelton, M,Kirwan, WO,Collins, JK,Shanahan, F (1998) Hepatitis C viral load variability in hepatitis C virus infected patients. Abstract [Details]
(1998)Minimal progression of hepatitis C type 1b in non immune compromised Irish women.
Cannon, BG,Loane, J,Corbett, S,Fanning, L,Kenny, E,Buckley, J,McFeely, L,Hogan, J,Devereux, C,Crowley, MJ,Whelton, MJ,Shanahan, F (1998) Minimal progression of hepatitis C type 1b in non immune compromised Irish women. Abstract [Details]
(1998)Sensitivity of PCR-based assays for hepatitis c virus can be influenced by choice of DNA polymerase.
Mullan, BM,Kenny-Walsh, E,Collins, JK,Shanahan, F,Fanning, LJ (1998) Sensitivity of PCR-based assays for hepatitis c virus can be influenced by choice of DNA polymerase. Abstract [Details]
(1998)Viral persistence or clearance in Hepatitis C (1b) infection: Relationship with HLA class II type.
Fanning, L,Levis, J,Kenny-Walsh, E,Collins, JK,Shanahan, F (1998) Viral persistence or clearance in Hepatitis C (1b) infection: Relationship with HLA class II type. Abstract [Details]
(1998)Serum viral load and clincopathologic progression of hepatitis C (1b): A study in a homogenous patient population.
Fanning, L,Kenny, E,Collins, JK,Sheehan, M,Shanahan, F (1998) Serum viral load and clincopathologic progression of hepatitis C (1b): A study in a homogenous patient population. Abstract [Details]
(1997)The relationship of serum quantitative PCR, aminotransferases and liver histology in monitoring the progression of chronic hepatitis C.
Fanning, L,Kenny, E,Cannon, B,Crowley, M,Shanahan, F (1997) The relationship of serum quantitative PCR, aminotransferases and liver histology in monitoring the progression of chronic hepatitis C. Abstract [Details]
(1996)Does qualitative PCR understage viraemic status in hepatitis C?.
Fanning, L,KennyWalsh, E,Collins, K,Whelton, MJ (1996) Does qualitative PCR understage viraemic status in hepatitis C?. Abstract [Details]
(1990)CLASS-SWITCH RECOMBINATION IN EXTRACHROMOSOMAL DNA SUBSTRATES IN MURINE PRE-B-CELLS.
FANNING, LJ,OREGAN, E,MCCARTHY, S,MCCARTHY, TV (1990) CLASS-SWITCH RECOMBINATION IN EXTRACHROMOSOMAL DNA SUBSTRATES IN MURINE PRE-B-CELLS. Abstract [Details]

Book Reviews

 YearPublication
(2005)Anti-viral therapies for hepatitis C virus infection: Current options and evolving candidate drugs.
Fanning, LJ (2005) Anti-viral therapies for hepatitis C virus infection: Current options and evolving candidate drugs. Book Reviews [Details]
(2007)In vitro replication models for the hepatitis C virus.
Sheehy, P,Mullan, B,Moreau, I,Kenny-Walsh, E,Shanahan, F,Scallan, M,Fanning, LJ (2007) In vitro replication models for the hepatitis C virus. Book Reviews [DOI] [Details]

Other

 YearPublication
(2009)Histological Changes in Hepatitis C Virus Antibody-Positive, Hepatitis C Virus RNA-Negative Subjects Suggest Persistent Virus Infection.
Moreau, I,Kenny-Walsh, E,Crosbie, O,Fanning, LJ (2009) Histological Changes in Hepatitis C Virus Antibody-Positive, Hepatitis C Virus RNA-Negative Subjects Suggest Persistent Virus Infection. Other [DOI] [Details]
(2006)Hepatitis B genotype and YMDD profiles in an untreated Irish population.
Horgan, M,Brannigan, E,Crowley, B,Levis, J,Fanning, LJ (2006) Hepatitis B genotype and YMDD profiles in an untreated Irish population. Other [DOI] [Details]
(2008)Molecular Epidemiology and Interferon Susceptibility of the Natural Recombinant Hepatitis C Virus Strain RF1_2k/1b.
Kurbanov, F,Tanaka, Y,Chub, E,Maruyama, I,Azlarova, A,Kamitsukasa, H,Ohno, T,Bonetto, S,Moreau, I,Fanning, LJ,Legrand-Abravanel, F,Izopet, J,Naoumov, N,Shimada, T,Netesov, S,Mizokami, M (2008) Molecular Epidemiology and Interferon Susceptibility of the Natural Recombinant Hepatitis C Virus Strain RF1_2k/1b. Other [DOI] [Details]

Published abstracts

 YearPublication
(2013)New paradigms for the modulatory actions of p38 delta MAPK restorative expression in esophageal squamous cancer cell growth, migration and response to chemotherapy: A possible future therapeutic target?.
O’Callaghan G, Fanning L, Houston A and Barry OP (2013) New paradigms for the modulatory actions of p38 delta MAPK restorative expression in esophageal squamous cancer cell growth, migration and response to chemotherapy: A possible future therapeutic target?. Published abstracts [Details]
(2012)Targeting p38 delta MAPK in Oesophageal Cancer: A Possible Future Therapeutic Goal?.
O’Callaghan G, Fanning L, Houston A and Barry OP (2012) Targeting p38 delta MAPK in Oesophageal Cancer: A Possible Future Therapeutic Goal?. Published abstracts [Details]

Professional Activities

Honours and Awards

 YearTitleAwarding Body
2013President's Award for Research into Innovative forms of Teaching and Learning Ionad Bairre, University College Cork, Ireland.

Professional Associations

 AssociationFunctionFrom / To
Americian Association for Microbiology Bacterial and Viral Pathogens01-DEC-09 / 31-DEC-12
American Association for the Study of the Liver Research matters relating to liver disease and infection01-APR-07 /

Conference Contributions

 YearPublication
(2014)Irish Society of Immunology,
Lyons C, Moran R, Fanning L, Houston A and Brint E (2014) Double-stranded RNA-induced inflammatory responses in macrophages are modified by Fas Signalling. [Poster Presentation], Irish Society of Immunology, Dublin . [Details]
(2013)CASI,
O'Sullivan K., Fanning L., O'Mullane J., ST4050 Students (2013) Analysis of Lower Limits of Detection of Hepatitis C Virus. [Poster Presentation], CASI, Clane Co. Kildare , 15-MAY-13 - 17-MAY-13. [Details]
(2010)Conference on Applied Statistics in Ireland,
Doherty, C., O’Sullivan, K., O’Mullane, J., McCarthy, C., Fanning, L.J. (2010) Identification of Subgroups of Chronic Hepatitis C Individuals. [Poster Presentation], Conference on Applied Statistics in Ireland, Portrush, Northern Ireland , 16-MAY-10 - 18-MAY-10. [Details]
(2010)1st World Congress of Viruses and Infections,
Liam Fanning; (2010) Viruses. [Invited Oral Presentation], 1st World Congress of Viruses and Infections, Busan, South Korea , 31-JUL-10 - 03-AUG-10. [Details]
(2010)Viruses and Innate Immunity,
Liam Fanning; (2010) Hepatitis C. [Invited Oral Presentation], Viruses and Innate Immunity, Dublin, Ireland , 01-MAY-10 - 05-MAY-10. [Details]
(2009)Translational Health Research Conference,
Doherty C, McCarthy C, Vargyas E, O’Sullivan K, Levis J, Crosbie O, Kenny-Walsh E, and Fanning LJ (2009) Viral clustering in chronic hepatitis C. [Poster Presentation], Translational Health Research Conference, University College Cork, Ireland , 24-JUN-09 - 24-JUN-09. [Details]
(2008)Molecular Symposium,
Fanning, L; (2008) Conference Organisation. [Conference Organising Committee Chairperson], Molecular Symposium, England , 10-JUN-08 - 11-JUN-08. [Details]
(2008)Irish Disease Society of Ireland,
Fanning, L; (2008) Conference Organisation. [Conference Organising Committee Chairperson], Irish Disease Society of Ireland, Dublin , 11-JUN-08 - 13-JUN-08. [Details]
(2008)2nd International Conference on Bioinformatics and Biomedical Engineering (iCBBE),
Huang J., O'Sullivan, K., Kenny-Wlash, E., Crosbie, O., Lewis, J., Fanning, L.J. (2008) Nonlinear Mixed Effects Modelling Viral Load in Untreated Patients with Chronic Hepatitis C. [Oral Presentation], 2nd International Conference on Bioinformatics and Biomedical Engineering (iCBBE), China , 01-MAY-08 - 01-MAY-08. [Details]
(2007)Molecular Symposium,
Fanning, L; (2007) Conference Organisation. [Conference Organising Committee Chairperson], Molecular Symposium, England , 12-JUN-07 - 13-JUN-07. [Details]
(2006)Molecular Symposium,
Fanning, L; (2006) Conference Organisation. [Conference Organising Committee Chairperson], Molecular Symposium, England , 13-JUN-06 - 14-JUN-06. [Details]
(2005)Molecular Symposium,
Fanning, L; (2005) Conference Organisation. [Conference Organising Committee Chairperson], Molecular Symposium, England , 14-JUN-05 - 15-JUN-05. [Details]

Committees

 CommitteeFunctionFrom / To
MMI structured PhD co-ordination committee UCC /
Clinical Sciences Building Users Committee Chair/
Research, College Medicine /
Research, School Medicine - undergraduate 2009 /
Graduate Studies Committee, Department Medicine Chair/
Biological Safety The registration of work under the Regulations and associated notification to the EPA and other bodies as necessary.2010 / 2014

Employment

 EmployerPositionFrom / To
Department Medicine, UCC Lecturer, Hepatitis C Laboratory/
Department Medicine, UCC Senior Lecturer/
Department Medicine, UCC Director, Molecular Virology Diagnostic & Research Laboratory/

Education

 YearInstitutionQualificationSubject
1992UCC PHDMedicine
1987UCC BSC (HONS)Medicine

Journal Activities

 JournalRoleTo / From
Journal Of Infectious Diseases Referee-
American Journal Of Gastroenterology Referee-
Tissue Antigens Referee-
The Open Virology Journal Referee-
Pharmacogenetics And Genomics Referee-
Lancet Referee-
Clinical Infectious Diseases : An Official Publication Of The Infectious Diseases Society Of America Referee-
Journal Of Clinical Virology Referee-
Immnogenetics Referee-
Genes And Immunity Referee-
Gastroenterology Referee-
European Journal Of Gastroenterology And Hepatology Referee-
Journal Of Hepatology Referee-

Teaching Activities

Current Postgraduate Students

 StudentDegree Type
O Callaghan Carol Doctoral Degree
Harty Ciara Doctoral Degree (Structured)
Naik Amruta Doctoral Degree (Structured)

Modules Taught

 Term (ID))TitleLinkSubject
2015Gastrointestinal Health: Mouth to Anus SH7004Gastrointestinal Health: Mouth to Anus
2015Skills and Professional Development (NUIG) SH7020Skills and Professional Development (NUIG)
2015Biological Imaging SH7011Biological Imaging
2015Case Studies in Research Ethics (UCD) SH7019Case Studies in Research Ethics (UCD)
2015Biostatistics SH7018Biostatistics
2015Integrated Pharmacology SH7012Integrated Pharmacology
2015Molecular Medicine: Human Disease SH7010Molecular Medicine: Human Disease
2015Molecular Mechanisms of Disease Pathogenesis SH7009Molecular Mechanisms of Disease Pathogenesis
2015Case Studies in Drug Discovery & Development (UCD) SH7021Case Studies in Drug Discovery & Development (UCD)
2015Communication, Teamwork and Research Ethics SH7017Communication, Teamwork and Research Ethics

Contact details


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Department of Medicine

Roinn na Sláinte

Clinical Sciences Building, Cork University Hospital , T12 EC8P

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