Biography
Dara Fitzpatrick is an award winning lecturer in Analytical Chemistry in UCC. He undertook research for a Ph.D. at Trinity College Dublin under the supervision of Prof. John Corish in the area of transdermal drug delivery. This was followed by a European Framework V postdoctoral fellowship in the area of transdermal drug delivery modelling with training in HSE Sheffield and Amsterdam. He also obtained a H.Dip in statistics during this time from Trinity College Dublin.
His current research interest is the development of a pioneering new acoustic spectroscopic instrument called BARDS (Broadband Acoustic Resonance Dissolution Spectroscopy). This new platform technology is creating a paradigm shift in the analysis of powders, blends, tablets and rapid dissolution formulations. It has multiple applications including the ability to differentiate polymorphs and infer particle size distributions. The research has lead to the creation of a spin-out company with sales of instruments to global companies such as GSK. http://www.bards.ie/
The Analytical Scientist has awarded BARDS one of the top 10 innovations of 2014 among the top global instrumentation companies. BARDS received a Pfizer Awards for 'Innovation through Teamwork' in 2013 and also a commendation at the APS conference in Edinburgh 2013. Dara has been nominated twice by Enterprise Ireland for the 'One to Watch Award'.
Dr. Fitzpatrick has published and been cited widely in high impact international journals such as Analytical Chemistry, International Journal of Pharmaceutics, Chemosphere and also a front cover of Analyst in 2014 with a 'hot article' called Rapid profiling of enteric coated drug delivery spheres via Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS). He has also authored two book chapters and presented over 25 papers at international conferences. He also acts as a reviewer for many of these publications.
He has been awarded over €1.2 million in competitive research funding in the last five years through Enterprise Ireland, Science Foundation Ireland and The Irish Research Council. Collaborations with the Food and Pharma sectors have also brought in significant research funding with break through outputs. He is currently contacting potential partners for a EU Cost action on Dissolution Science.
Dr. Fitzpatrick also led the Instrumentation theme in the SFI funded Irish Separation Science Cluster http://www.separationscience.ie/
Dr. Fitzpatrick has given many invited lectures at symposia and chaired and organised the Conference of Analytical Science in Ireland 2013, with 120 delegates with both national and international speakers. http://www.ucc.ie/en/casi/ Dara is also on the local organising committee for the International Chromatographic Society Conference in 2016. http://www.isc2016.ie/
He has served, and is serving on many departmental committees including research, safety and outreach which he chaired with JJ.Keating such were the number of activities. He has helped to organise and run the Salters Festival for over a decade. He is also on the UCC Green Campus Committee to help sustain UCC’s position in the top three green campuses in the world.
Dara is a member of several professional societies including the Institute of Chemistry in Ireland and the Royal Society of Chemistry. He’s also a member of the Joint Pharmaceutical and Analytical Group which is a joint committee between the RSC and the Royal Pharmaceutical Society.
Dr. Fitzpatrick has acted as an external examiner for DIT, DCU and UCD.
On the teaching front, Dara has been awarded the President’s Award for Innovative Forms of Teaching and continues to deliver high quality teaching as measured by centralised module feedback from the University. He has supervised over 20 Masters thesis and has, or currently, supervises 7 Ph.D., 5 postdocs and a Senior Research Associate. Dara contributes to teaching from 1st year to masters level in Chemistry, Forensics, Pharmacy, Engineering and Environmental. He also contributes to further education through night courses in Environmental management.
Research Interests
Audible Sound Waves as a new form of Spectroscopy
Environmental monitoring of habitats under conservation.
In-vitro and in-vivo bio-analysis of pharmaceutical compounds with a special interest in transdermal drug delivery.
Risk assessment and predictive modelling of exogenous compounds via the dermal route. (Framework V project Edetox http://www.ncl.ac.uk/edetox/
Evaluation and applications of Partition and distribution Co-efficients in PBPK, Environmental and Bio-modelling.
Research Grants
| Project | Funding Body | Start Date | End Date | Award | |
|---|---|---|---|---|---|
| Forensic impurity profiling and synthesis of Hallucinogenic Amphetamine-type drugs of abuse. | Irish Research Council for Science, Engineering & Technology (IRCSET) | 01-OCT-09 | 30-SEP-13 | €72,009.00 | |
| Broadbank Acoustic Resonance Dissolution Spectroscopy - Applications Development and Market Expansion. | Enterprise Irl | 01-OCT-11 | 30-SEP-14 | €397,471.00 | |
| IRC"EPSPG/2014/84 M Riz"Dr D Fitzpatrick | Irish Research Council | 01-OCT-14 | 30-SEP-18 | €95,800.00 | |
| Irish Separation Science Cluster | Science Foundation Ireland | 01-JAN-10 | 31-DEC-14 | €140,000.00 | |
| EI "Acoustic Resonance Spectroscopy" | Enterprise Irl | 01-APR-05 | 31-OCT-06 | €50,507.00 | |
| Investigation and characterisaition of enantiomeric ratios of mixtures of isomers using BARDS. | Irish Research Council for Science, Engineering & Technology (IRCSET) | 03-OCT-11 | 31-MAY-15 | €72,000.00 | |
| The Development and Validation of ICP-MS Metholds for the Speciation of Potential Toxins in Food and Beverages. | Irish Research Council for Science, Engineering & Technology (IRCSET) | 01-FEB-12 | 14-DEC-12 | €91,790.00 | |
| Broadbane Acourstic Resonance Dissolution Spectroscopy. | Irish Research Council for Science, Engineering & Technology (IRCSET) | 01-SEP-11 | 31-AUG-13 | €79,280.00 | |
| Broadband Acoustic Resonance Dissolution Specteroscopy - A Universal Comparator for Compound Characterisation. | Enterprise Irl | 01-JAN-10 | 30-JUN-12 | €312,291.00 |
Publications
Peer Reviewed Journals
| Year | Publication | |
|---|---|---|
| (2010) | 'Micellar electrokinetic chromatography with amperometric detection and off-line solid-phase extraction for analysis of carbamate insecticides' Santalad, A,Zhou, L,Shang, FJ,Fitzpatrick, D,Burakham, R,Srijaranai, S,Glennon, JD,Luong, JHT (2010) 'Micellar electrokinetic chromatography with amperometric detection and off-line solid-phase extraction for analysis of carbamate insecticides'. Journal of chromatography. A, 1217 :5288-5297 [DOI] [Details] | |
| (2008) | 'Release Characteristics of Anionic Drug Compounds from Liquid Crystalline Gels IV: Chemical and Iontophoretic Enhancement of Delivery across Human Stratum Corneum' D.Fitzpatrick and J.Corish; (2008) 'Release Characteristics of Anionic Drug Compounds from Liquid Crystalline Gels IV: Chemical and Iontophoretic Enhancement of Delivery across Human Stratum Corneum'. International Journal of Pharmaceutics, [Details] | |
| (2007) | 'Combined Effects of Iontophoretic and Chemical Enhancement On Drug Delivery - II. Transport Across Human and Murine Skin' Nolan, LMA, Corish, J, Corrigan, OI, Fitzpatrick, D; (2007) 'Combined Effects of Iontophoretic and Chemical Enhancement On Drug Delivery - II. Transport Across Human and Murine Skin'. International Journal of Pharmaceutics, 341 (1-2):114-124 [DOI] [Details] | |
| (2006) | 'Release Characteristics of Anionic Drug Compounds From Liquid Crystalline Gels - III. Chemical and Iontophoretic Enhancement of Delivery Across Non-Rate-Limiting Membranes' Fitzpatrick, D, Corish, J; (2006) 'Release Characteristics of Anionic Drug Compounds From Liquid Crystalline Gels - III. Chemical and Iontophoretic Enhancement of Delivery Across Non-Rate-Limiting Membranes'. International Journal of Pharmaceutics, 325 (1-2):90-98 [DOI] [Details] | |
| (2014) | 'Rapid profiling of enteric coated drug delivery spheres via Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS)' Fitzpatrick, D,Evans-Hurson, R,Fu, Y,Burke, T,Kruse, J,Vos, B,McSweeney, SG,Casaubieilh, P,Keating, JJ (2014) 'Rapid profiling of enteric coated drug delivery spheres via Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS)'. Analyst, 139 :1000-1006 [DOI] [Details] | |
| (2014) | 'Aspirated bile: a major host trigger modulating respiratory pathogen colonisation in cystic fibrosis patients' Reen, FJ,Woods, DF,Mooij, MJ,Chroinin, MN,Mullane, D,Zhou, L,Quille, J,Fitzpatrick, D,Glennon, JD,McGlacken, GP,Adams, C,O'Gara, F (2014) 'Aspirated bile: a major host trigger modulating respiratory pathogen colonisation in cystic fibrosis patients'. European Journal of Clinical Microbiology & Infectious Diseases, 33 :1763-1771 [DOI] [Details] | |
| (2005) | 'Release characteristics of anionic drug compounds from liquid crystalline gels - I: Passive release across non-rate-limiting membranes. International Journal of Pharmaceutics' Fitzpatrick, D.,Corish, J.; (2005) 'Release characteristics of anionic drug compounds from liquid crystalline gels - I: Passive release across non-rate-limiting membranes. International Journal of Pharmaceutics'. International Journal of Pharmaceutics, 301 (1-2):226-236 [Details] | |
| (2003) | 'Iontophoretic and chemical enhancement of drug delivery - Part 1: Across artificial membranes. International Journal of Pharmaceutics' Nolan, L. M. A.,Corish, J.,Corrigan, O. I.,Fitzpatrick, D.; (2003) 'Iontophoretic and chemical enhancement of drug delivery - Part 1: Across artificial membranes. International Journal of Pharmaceutics'. International Journal of Pharmaceutics, 257 (1-2):41-55 [Details] | |
| (2006) | 'Release characteristics of anionic drug compounds from liquid crystalline gels Part II. The effects of ion pairing and buffering on the passive delivery of anionic drugs across non-rate-limiting membranes' Fitzpatrick, D,Corish, J; (2006) 'Release characteristics of anionic drug compounds from liquid crystalline gels Part II. The effects of ion pairing and buffering on the passive delivery of anionic drugs across non-rate-limiting membranes'. International Journal of Pharmaceutics, 311 :139-146 [DOI] [Details] | |
| (2004) | 'Modelling skin permeability in risk assessment - the future' Fitzpatrick, D,Corish, J,Hayes, B; (2004) 'Modelling skin permeability in risk assessment - the future'. Chemosphere, 55 :1309-1314 [DOI] [Details] | |
| (2012) | 'Blend uniformity analysis of pharmaceutical products by Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS)' Fitzpatrick, D,Scanlon, E,Kruse, J,Vos, B,Evans-Hurson, R,Fitzpatrick, E,McSweeney, S (2012) 'Blend uniformity analysis of pharmaceutical products by Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS)'. International Journal of Pharmaceutics, 438 :134-139 [DOI] [Details] | |
| (2013) | 'The relationship between dissolution, gas oversaturation and outgassing of solutions determined by Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS)' Fitzpatrick, D,Evans-Hurson, R,Kruse, J,Vos, B,McSweeney, S,Casaubieilh, P,O'Gorman, E (2013) 'The relationship between dissolution, gas oversaturation and outgassing of solutions determined by Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS)'. Analyst, 138 :5005-5010 [DOI] [Details] | |
| (2012) | 'Principles and Applications of Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS): A Sound Approach for the Analysis of Compounds' Dara Fitzpatrick, Jacob Krüse, Bastiaan Vos, Owen Foley, Donncha Gleeson, Eadaoin O’Gorman, (2012) 'Principles and Applications of Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS): A Sound Approach for the Analysis of Compounds'. Analytical Chemistry, [DOI] [Details] | |
| (2010) | '2,4,6-Trichlorophenol mediated increases in extracellular peroxidase activity in three species of Lemnaceae' Biswas, DK,Scannell, G,Akhmetov, N,Fitzpatrick, D,Jansen, MAK; (2010) '2,4,6-Trichlorophenol mediated increases in extracellular peroxidase activity in three species of Lemnaceae'. Aquatic Toxicology, 100 :289-294 [DOI] [Details] |
Book Chapters
| Year | Publication | |
|---|---|---|
| (2011) | 'Atomic Spectrometric Techniques' C. M. M. Smith, D. Fitzpatrick, and J. D. Glennon; (2011) 'Atomic Spectrometric Techniques' In: Encyclopedia of Dairy Sciences. United States: Academic Press. [Details] | |
| (2007) | 'Modelling Skin Permeability in Risk Assessment' Dermal Absorption and Toxicity Assessment' D.Fitzpatrick and J.Corish; (2007) 'Modelling Skin Permeability in Risk Assessment' Dermal Absorption and Toxicity Assessment' In: Dermal Absorption and Toxicity Assessment. Madison Avenue, New York: Taylor and Francis. [Details] |
Professional Activities
Honours and Awards
| Year | Title | Awarding Body | |
|---|---|---|---|
| 2005 | Presidents Award for research into Innovative forms of Teaching (integrating teaching with research) | UCC | |
| 2012 | One to Watch Nominee | Enterprise Ireland | |
| 2010 | One to Watch Nominee | Enterprise Ireland | |
| 2013 | Commendation | Academy of Pharmaceutical Sciences | |
| 2013 | Pfizer Innovation Through Teamwork Award | Pfizer / UCC | |
| 2014 | The Analytical Scientist Innovation Award | The Analytical Scientist Publication |
Professional Associations
| Association | Function | From / To | |
|---|---|---|---|
| Institute of Chemistry in Ireland | Member | 01-JAN-95 / 13-JAN-15 | |
| The Royal Society of Chemistry | Member | 01-JAN-00 / 13-JAN-15 |
Patents
| Patent Number | Title | Granted | |
|---|---|---|---|
| WO2009130214 A | Broadband Acoustic Resonance Dissolution Spectroscopy | 21-APR-13 |
Conference Contributions
| Year | Publication | |
|---|---|---|
| (2008) | Seminar Series, D> Fitzpatrick; (2008) Broadband Acoustic Resonance Dissolution Spectroscopy. [Oral Presentation], Seminar Series, IT Tallaght , 01-MAY-08 - 01-MAY-08. [Details] | |
| (2006) | Perspectives in Percutaneous Penetration, D.Fitzpatrick; (2006) Combined effects of iontophoretic and chemical enhancement on drug delivery. [Oral Presentation], Perspectives in Percutaneous Penetration, La Grande Motte, France , 01-APR-06 - 07-APR-06. [Details] | |
| (2004) | Perspectives in Percutaneous Penetration, D.Fitzpatrick; (2004) Determination of Partition and Distribution Coefficients using HPLC for use in Transdermal Modelling. [Invited Lectures (Conference)], Perspectives in Percutaneous Penetration, La Grande Motte, France , 01-APR-04 - 01-APR-04. [Details] | |
| (2004) | Perspectives in Percutaneous Penetration 2004, D.Fitzpatrick; (2004) Determination of Partition and Distribution Coefficients using HPLC for use in Transdermal Modelling. [Oral Presentation], Perspectives in Percutaneous Penetration 2004, La Grande Motte, France , 01-APR-04 - 03-APR-04. [Details] | |
| (2002) | Perspectives in Percutaneous Penetration 2002, D.Fitzpatrick; (2002) Passive and enhanced transdermal transport of anionic drug molecules. [Oral Presentation], Perspectives in Percutaneous Penetration 2002, Antibes Juan les Pins, France , 01-APR-02 - 01-APR-02. [Details] | |
| (2010) | HPLC 2010, Dara Fitzpatrick, Bastiaan Vos, Jacob Krüse, Eadaoin O’Gorman, Damien Browne (2010) Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS): A novel technique for compound analysis. [Poster Presentation], HPLC 2010, Boston, Massachusetts, USA , 19-JUN-10 - 24-JUN-10. [Details] | |
| (2011) | Chirality 2011, Dara Fitzpatrick, Bastiaan Vos, Jacob Krüse, Donnacha Gleeson (2011) Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS): A novel technique for chiral analysis. [Poster Presentation], Chirality 2011, Liverpool, England , 10-JUL-11 - 13-JUL-11. [Details] | |
| (2011) | ISIC 18 International Symposium on Industrial Crystallisation, Dara Fitzpatrick, Bastiaan Vos, Jacob Krüse, Owen Foley, Donnacha Gleeson (2011) Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS): A sound approach to morphological analysis. [Poster Presentation], ISIC 18 International Symposium on Industrial Crystallisation, Zurich, Switzerland , 13-SEP-11 - 16-SEP-11. [Details] | |
| (2011) | CHAINS (Chemistry as Innovating Science), Dara Fitzpatrick, Jacob Kruse and Bastiaan Vos (2011) Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS):A Sound Approach to Morphological Analysis. [Poster Presentation], CHAINS (Chemistry as Innovating Science), Utrecht, The Nederlands , 28-NOV-11 - 30-NOV-11. [Details] | |
| (2011) | Institute of Chemistry in Ireland Annual Congress 2011, Dara Fitzpatrick (2011) Reducing Risk and Increasing Potential in Commercialisation. [Invited Lectures (Conference)], Institute of Chemistry in Ireland Annual Congress 2011, DIT, Dublin, Ireland , 27-MAY-11 - 27-MAY-11. [Details] | |
| (2011) | 6th Conference on Analytical Sciences Ireland (CASi 2011), Fengjun Shang, Apichai Santalad, Lin Zhou, Dara Fitzpatrick, Rodjana Burakham, Supalax Srijaranai, Jeremy D. Glennon; (2011) Micelar electrokinetic chromatograpghy with amperometric detection for analysis of carbanmate onsecticides. [Poster Presentation], 6th Conference on Analytical Sciences Ireland (CASi 2011), Dublin, Ireland , 21-FEB-11 - 22-FEB-11. [Details] | |
| (2011) | Conference on Analytical Sciences in Ireland 2011, 6th CASI, Dara Fitzpatrick (2011) The Principles and Applications of Broadband Acoustic Resonance Dissolution Spectroscopy. [Invited Oral Presentation], Conference on Analytical Sciences in Ireland 2011, 6th CASI, DCU, Dublin, Ireland , 21-FEB-11 - 22-FEB-11. [Details] |
Employment
| Employer | Position | From / To | |
|---|---|---|---|
| UCC Dept of Chemistry | College Lecturer | 01-SEP-02 / | |
| Trinity College Dublin | Postdoctoral Research Fellow (Framework V) | / | |
| IT-Tallaght | Part Time Lecturer | / |
Education
| Year | Institution | Qualification | Subject | |
|---|---|---|---|---|
| 1995 | IT Tallaght | DIPLOMA | ||
| 1996 | IT Athlone | B.Sc. | ||
| 2000 | Trinity College Dublin | Ph.D. | ||
| 1999 | Trinity College Dublin | HDip | Statistics |
Teaching Activities
Teaching Interests
On-Line Lecture Notes:
CM1001
CM2007
CM2009
CM3024
CM3107
CM4024
CM4110
CM4111
CM4100
MSc/H.Ddip (Analytical+Biotech)
PF2102
Contact details
- Dara Fitzpatrick
Lecturer - d.fitzpatrick@ucc.ie
- Chemistry
CHEMISTRY
University College Cork
Cork
Ireland - +353-21-490-3299
- +353-21-427-4097
- Lecturer
- d.fitzpatrick@ucc.ie
- Chemistry
University College Cork
Cork
Ireland - +353-21-490-3000